Abstract: The invention refers to an engine for an auto-injector for administering a dose of a liquid medicament, the engine comprising a case having a distal end and a proximal end arranged to be attached to a packaged syringe containing a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, wherein the syringe is slidably arranged with respect to the case, the case containing: drive means capable of, upon activation: pushing the needle from a covered position into an exposed position, and operating the syringe to supply the dose of medicament, and activating means arranged to lock the drive means in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that the drive means is arranged as a gas spring comprising a cylinder and a piston with a plunger for transmitting the spring force, wherein a compressed gas is provided in a high pressure cavity defined between the piston and a dista

Abstract: Embodiments of the present invention include a self-powered infuser with a medicament containing vessel coupled to the infuser capable of exerting sufficient pressure to cause a medicament to flow from the containing vessel, through intravenous tubing, and into a patient's circulatory system. The infuser and vessel may be contained within a sealable kit which may have a separate container for perishable medications such that the medications may be inspected and changed without exposing the remainder of the kit's contents. The infuser may be recyclable or disposable.

Abstract: A dispensing device for dispensing medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways. Because the stand-alone fluid delivery and control assembly is initially totally separate from the fluid reservoir assembly of the apparatus, the fluid flow passageways of the fluid delivery and control assembly can be effectively sterilized using conventional gamma ray sterilization techniques without adversely affecting the medicament contained within the fluid reservoir of the apparatus.

Abstract: A fluid collection system includes a disposable collection container and a disposable collection container receiving housing, the housing having a cavity and a suction source. The fluid collection container may include a flexible liner and a shelf for diverting fluid from the suction and to assist with a collapse of the liner during evacuation of the fluid from the liner. The collection container receiving housing may include a piston assembly having a main piston body and a scraper ring. The collection container receiving housing may include a piston stop feature. The system may include a partially hydrophobic filter and a flat surface suction tool.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to undergo incremental advancement. The device may also be provided with manual control for delivering a bolus dose of drug when necessary.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to undergo incremental advancement. The device may also be provided with manually control for delivering a bolus dose of drug when necessary.

Abstract: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary.

Abstract: Remote controls, including a communication device, a button or other communication device actuator and a movable structure that allows actuation of the actuator in one position and prevents actuation of the actuator in another position to prevent inadvertent signal transmission.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible drug container that can be filled in the field with the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: Embodiments of the present invention include a self-powered infuser with a medicament containing vessel coupled to the infuser capable of exerting sufficient pressure to cause a medicament to flow from the containing vessel, through intravenous tubing, and into a patient's circulatory system. The infuser and vessel may be contained within a sealable kit which may have a separate container for perishable medications such that the medications may be inspected and changed without exposing the remainder of the kit's contents. The infuser may be recyclable or disposable.

Abstract: The technical field of the invention is that of needleless pre-filled disposable syringes, operating with a gas generator, and used for intradermal, subcutaneous and intramuscular injections, of a liquid active principle for therapeutic use in human and veterinary medicine. The inventive needleless syringes use a reservoir (5) consisting of a tube (6) closed by an upstream plug-piston (7) and a downstream plug-piston (8) between which is contained the liquid active principle. Said needleless syringes are characterized in that they are capable of injecting a variable amount of liquid active principle (9) by adapting, through displacement of the downstream plug-piston (8) in the tube (6) the volume included between the two plug-pistons (7,8) to the amount of active principle (9) to be injected.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose Of drug when necessary.

Abstract: An apparatus includes a medicament container and an actuator assembly coupled to a proximal end portion of the medicament container. A distal end portion of the medicament container is configured to be coupled to a needle. A piston is movably disposed within the medicament container such that the medicament container is divided into a first internal portion and a second internal portion, the first internal portion containing a medicament. The actuator assembly has a pressurized fluid container, a regulator and a bias member. The pressurized fluid container is configured to move relative to the medicament container between a first position and a second position. The regulator is configured to fluidically couple the pressurized fluid container and the second internal portion of the medicament container when the pressurized fluid container is in the second position. The bias member is configured to bias the pressurized fluid container in the first position.

Abstract: A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary.

Abstract: A device has at least one chamber for accommodating a medicament or a sample volume, and has a plunger element which is displaceable in the device. The device includes a syringe or carpule, a multi- or dual-chamber system, an autoinjector, or a pen. Pressure forces resulting from a chemical reaction may be introduced into the plunger element, thereby causing displacement of the plunger element.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible drug container that can be filled in the field with the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.

Abstract: A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.

Abstract: A catheter having a drug delivery unit at the distal end thereof. The drug delivery unit includes an actuator capable of assuming an activated and an inactivated configuration. The drug delivery unit also includes a receptacle capable of accepting a therapeutic agent. The actuator and receptacle are in communication with each other such that the actuator transmits force to the receptacle and the receptacle accepts force from the actuator in an activated configuration of the actuator. Also provided is a method of delivering a therapeutic agent to a target site using the catheter of the present invention.

Abstract: Tissue sensors house one or more sensor elements. Each element has a housing mounted substrate and a superstrate with a planar antenna between. A transitional periphery (TP) of a superstrate outer surface interconnects a base to a plateau. At least some of the TP has a generally smooth transition. Plural elements are spaced by the housing. Alternately, the superstrate TP is flat, the housing extends to the outer superstrate surface and a shield surrounds the element. The housing is flush with or recessed below the superstrate and defines a TP between the housing and superstrate. A method converts a reference signal to complex form; plots it in a complex plane as a reference point (RP); converts a measurement signal to complex form; plots it in the complex plane as a measurement point (MP); determine a complex distance between the MP and the RP; and compares complex distance to a threshold.

Abstract: An apparatus includes a tubular member and a spherical piston disposed within a lumen defined by the tubular member. The tubular member includes a distal end portion and a central portion. The distal end portion is configured to be coupled to a needle. At least the central portion of the tubular member is curved. The spherical piston is movably disposed with the lumen such that the lumen is divided into a first portion and a second portion. The first portion of the lumen configured to contain a medicament.

Abstract: The invention concerns the field of pre-filled and disposable needleless syringes, operating with a gas generator and used for intradermal, subcutaneous and intramuscular injections of a liquid active principle for therapeutic purposes in human and veterinary medicine. Said injection device (1) is mainly characterized in that it has a free pressuring space (26) around the reservoir (20) of the active principle (17) so that the gases produced by the gas generator (4) instantly penetrate said pressurizing space (26), compressing said reservoir (20) just before causing the plunger to move (18) to expel the liquid active principle (17). During said displacement, the reservoir (20) is subjected to a state of equal pressure.

Abstract: The invention relates to a micropump comprising at least one gas releasing material which drives a piston towards a second material containing a drug material which is released through a semi permeable membrane and/or flow restrictor

Abstract: An apparatus includes a medicament container and an actuator assembly coupled to a proximal end portion of the medicament container. A distal end portion of the medicament container is configured to be coupled to a needle. A piston is movably disposed within the medicament container such that the medicament container is divided into a first internal portion and a second internal portion, the first internal portion containing a medicament. The actuator assembly has a pressurized fluid container, a regulator and a bias member. The pressurized fluid container is configured to move relative to the medicament container between a first position and a second position. The regulator is configured to fluidically couple the pressurized fluid container and the second internal portion of the medicament container when the pressurized fluid container is in the second position. The bias member is configured to bias the pressurized fluid container in the first position.

Abstract: An ophthalmic injection system is disclosed. The system has a dispensing member, a plunger, an actuation chamber, a lock mechanism, a lock stop, a port, a source of pressurized gas, and a shaft. The lock mechanism travels in the actuation chamber in an axial direction toward and away from a distal end of the dispensing member. The lock stop is located on the inner surface of the actuation chamber. The lock stop is engageable with the lock mechanism such that when the lock mechanism travels in the axial direction toward the distal end of the dispensing member to a first position located on a distal side of the lock stop, the lock mechanism cannot travel in a reverse direction away from the distal end of the dispensing member to a location on a proximal side of the lock stop.

Abstract: A method is disclosed for delivering a quantity of a substance into an eye. By applying compressed gas into an actuation chamber, a separating member connected to a lock mechanism and a plunger is displaced. The plunger displaces the quantity of the substance from a dispensing member and into an eye. The plunger is retained in an extended position so that the quantity of the substance is not retracted back into the dispensing member when the dispensing member is removed from the eye.

Abstract: A high-speed pneumatic cutting system having a cutter and an actuator. The cutter is a guillotine-type, pneumatic cutter that receives a train of pressure pulses from the actuator. The actuator is designed to capture pressure pulses it receives from a pneumatic energy source in a surgical machine, such as a vitrectomy machine, or to generate its own pneumatic energy. The actuator has an accumulator coupled to the outlet of the pneumatic energy and a pressure transducer that senses the pressure level inside the accumulator. A control and display unit with a plurality of input mechanisms receives inputs from a user who selects a desired cutting rate or frequency for the cutter. The control and display unit produces an output signal based on the inputs received. The outputs from the control and display unit and the pressure transducer are sent to a waveform shaping circuit. The waveform shaping circuit produces a command signal based on the inputs that it receives.

Abstract: The invention provides a continuous liquid infusion device in which liquid syringe and a negative pressure cylinder are separable to use a liquid infused syringe. This continuous liquid infusion device includes: a negative pressure cylinder having a barrel part including an open/close valve at its tip and leg parts extending from a base end thereof; a piston air-tightly fitted in the barrel part and connected to a base end of an outer case covering an outer surface of the barrel part, through slots between the leg parts; a liquid syringe having a liquid infusion/discharge port at its tip, and a base end screwed with the outer case so that the liquid syringe is positioned back to back with the negative pressure cylinder; and a movable unit liquid-tightly fitted to an inner circumference of the tip of the liquid syringe and abutting against a base end of the leg parts.

Abstract: A syringe comprises a barrel containing an internal cylindrical body containing a liquid and communicating with a delivery needle. The needle is covered before use by a removable sheath, and after the sheath is removed, the needle is concealed by a displaceable sleeve. In use the sleeve is pressed against the skin by applying pressure while holding the barrel. The sleeve is thereby retracted into the barrel allowing the needle to penetrate the skin. The movement of the sleeve also activates a gas generator which expels the liquid from the needle. When delivery is complete and the syringe is taken from the skin, a coil spring moves the sleeve back to the starting position again concealing the needle. The coil spring is torsionally biased before use and causes a rotational movement of the sleeve relative to the barrel when the sleeve moves into and out of the barrel. This rotational movement engages a locking mechanism which prevents further movement of the sleeve and thereby permanently conceals the needle.

Abstract: A drug delivery device having a base member defining a skin-contacting surface, a syringe serving as a reservoir for the drug, and means for expelling drug from the syringe. The syringe is connected to the base member such that the longitudinal axis of the syringe is substantially parallel to the skin surface. A delivery needle is in communication with the syringe. The needle has an angled bend which directs the tip of the needle substantially perpendicular to the skin-contacting surface. In use, the tip of the needle is adapted to penetrate the skin of the subject.

Abstract: A portable medication delivery system enables a patient to elect slow continuous auto-administration or rapid bolus self-administration of a fluid medication. The medication delivery system has an infusion pump, which includes a fluid storage chamber and a spring-driven piston positioned in the fluid storage chamber. The fluid storage chamber is initially charged with the medication and the infusion pump automatically delivers a continuous dosage of the medication at a first flow rate over a long time from the fluid storage chamber to a treatment site in the patient. A bolus injector is positioned in series or in parallel with the infusion pump and is charged with a bolus dosage of the treatment fluid from the fluid storage chamber for alternate manual self-injection of the medication into the treatment site at a higher second flow rate for a short time.

Abstract: A needleless injector system including: a first injector assembly; a gas capsule disposed within the first injector assembly and containing pressurized gas, with a pierceable surface at the forward end thereof to provide an injection source; a gas capsule piercing member disposed within the first injector assembly, where the piercing member and the gas capsule are movable relative to each other; a second injector assembly containing a medical treatment fluid and having a forward facing injection orifice for injecting the medical treatment fluid into a patient; and a resilient seal mounted between the gas capsule and the first injector assembly to contain all pressurized gas within a forward end of the first injector assembly after pressurized gas is released from the gas capsule following piercing of the gas capsule, in order to cause an immediate increase in pressure in the medical treatment fluid contained within the second injector assembly.

Abstract: The invention concerns the field of pre-filled and disposable needleless syringes, operating with a gas generator and used for intradermal, subcutaneous and intramuscular injections of a liquid active principle for therapeutic purposes in human and veterinary medicine. Said injection device (1) is mainly characterized in that it has a free pressuring space (26) around the reservoir (20) of the active principle (17) so that the gases produced by the gas generator (4) instantly penetrate said pressurizing space (26), compressing said reservoir (20) just before causing the plunger to move (18) to expel the liquid active principle (17). During said displacement, the reservoir (20) is subjected to a state of equal pressure.

Abstract: A gas-powered, single-use, needle-less hypodermic jet injection device (10, 210, 410) includes a hand-held injector (12, 212, 412), and a drug injection cartridge (14, 114, 414) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (82, 182, 482) which remains sealed until the moment of injection and powers the jet injection after opening of this cartridge.

Abstract: The invention relates to a continuous liquid infusion device which can be easily prepared for operation with small force, and can infuse liquid at constant infusion rate and amount over a long time. It comprises a liquid syringe section and a driving pump section mounted on the liquid syringe section, wherein sliding the pressing arm of the driving pump section upward leads to axially slides the piston in the negative pressure chamber to produce a negative pressure therein; and using returning force of the piston under the negative pressure, the liquid pushout plunger barrel is biased toward the upper edge of a pressing member through a locking member engaged with the piston so as to push out liquid in the liquid syringe from the liquid infusion port. Further, only the liquid syringe is disposable while the vacuum pump barrel on the driving side is good for repeated use (reusable).

Abstract: One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being aligned with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a portion of dried drug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.

Abstract: A gas-powered, single-use, needle-less jet injection device (10, 210, 410) includes a hand-held injector (12, 212, 412), and a drug injection cartridge (14, 114, 414) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (82, 182, 382) which remains sealed until the moment of injection and powers the jet injection after opening of this cartridge.

Abstract: One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being coaxial with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a drug plug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.

Abstract: A device for actively releasing material(s) (e.g. intra ruminally) having a plurality of dispensing reservoirs. Each electrolytic cell is capable upon energization under the control of a microprocessor after initiation of generating a gas which will cause (e.g. through action on a piston) by displacement of the material(s) of its respective reservoir sufficient displacement of or change to closure means of that reservoir thereby to allow release of the material(s).

Abstract: The present disclosure describes a system wherein a drug or other fluid to be delivered to a specific desired location within the body is stored in a reservoir that is directly displaced by a force to infuse the drug from the device into the patient. Several specific methods are used to displace the reservoir, including, generally, hydraulic displacement, mechanical screw-type displacement, and spring force displacement of the fluid reservoir.

Abstract: A propulsion system suitable for a single-use or a multi-use needleless injection device comprises a container and a source of potential energy for propelling a fluid (2) with sufficient pressure through an orifice to create a jet enabling subcutaneous or intracutaneous delivery of the fluid, the source of potential energy primarily in the form of a compressible substance (7) under pressure within the container. The compressible substance is preferably a polysiloxane or vulcanized silicon rubber.

Abstract: A gas-powered, single-use, needle-less hypodermic jet injection device includes a hand-held injector, and a drug injection cartridge which provides a cylinder of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston in the cylinder causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure capsule which remains sealed until the moment of injection and powers the jet injection after opening of this cartridge.