Abstract: A safety coupling for a fluid infusion device is provided. The device includes a first coupling device coupled to a drive system of the fluid infusion device, and a second coupling device coupled to a stopper of a fluid reservoir associated with the fluid infusion device. The first coupling device and the second coupling device cooperate to resist the movement of the stopper relative to the drive system.

Abstract: A penis erection stimulation system comprises one or more infusion needles, the tip ends of which are disposed within and implanted along with at least one first housing adjacent the patient's left and right corpora cavernosa. The respective other end or ends of the infusion needles are disposed and implanted along with at least one second housing remote from the first housing. A reservoir and a pump are also implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the infusion needle such that its tip end penetrates the at least one first housing's outer wall at least in two different penetration areas either simultaneously or in immediate time succession, thereby injecting drugs into the patient's body for stimulating penis erection.

Abstract: A method for calculating a meal bolus in an insulin pump and an insulin pump are disclosed. The insulin pump includes a pump mechanism and a memory configured to store a plurality of food entries in a food database. The insulin pump also includes a programmable circuit arranged to control the pump mechanism and operatively connected to the memory. The programmable circuit is programmed to accept entry of one or more food entries into the food database. The programmable circuit is also programmed to associate each of the one or more food entries with a carbohydrate value. The programmable circuit is programmed to prompt selection of one or more food entries. The programmable circuit is further programmed to calculate a meal bolus based on the one or more food entries.

Abstract: A programmable implantable pump is disclosed. The pump includes an implantable pump and a hermetically sealed module. The module provides for varying flow rates of fluid being dispensed from the pump or may provide for a constant flow rate of such fluid. In the case of varying flow rate capabilities, the module preferably includes one or more sensors to determine information relating to the pressure of the fluid, electronics for analyzing the pressure information and determining the flow rate of the fluid, and a mechanism for physically altering the flow rate. Methods of dispensing a medicament to a patient utilizing such a system are also disclosed, as are variations of the pump system.

Abstract: A catheter for use in medical applications is disclosed. The catheter comprises tubing with a tip hole at one end and an end portion at the other end. Fluid exits the catheter at the tip hole thereof. One or more alternative fluid pathway(s) are provided on the sidewall of the catheter to permit outflow of fluid medication from the catheter to ensure proper delivery of the medication to the intended target area, particularly when the tip opening is occluded or restricted for any reason.

Abstract: Embodiments relate to systems, methods and devices for delivering a drug or other therapy to a patient with an ambulatory infusion pump configured to provide a series of tolerance-building steps leading up to a plateau delivery rate. The plateau delivery rate is maintained until the prescribed amount of drug or therapy fluid is delivered to the patient. Embodiments of the invention include providing the patient or other user with a mechanism to decrease, or step down, the therapy delivery rate if a tolerance was not achieved at a lower rate, and providing notifications prior to a step up in a dosage delivery rate.

Abstract: A fluid infusion system that is configured to infuse fluid from a source to a patient. The fluid flows through tubing formed of one or more tube segments that define a fluid lumen. At least a portion of the tubing has a multi-layered configuration including an outer layer and an inner layer. The outer layer has one or more characteristics that are particularly suited for an outer layer such as to resist the environmental conditions that the tubing may experience.

Abstract: An orthopaedic implant system includes an external fixation device implantable at a selected location within a corporeal body and configured for delivering at least one therapeutic agent to the corporeal body. The external fixation device includes an implantable pin, a sheath coupled with the pin, a reservoir coupled with the sheath and a plurality of channels. The pin defines the plurality of channels. The reservoir is configured for receiving the at least one therapeutic agent. The plurality of channels are configured for conveying the at least one therapeutic agent from the reservoir to a treatment site relative to the corporeal body.

Abstract: The present invention provides a selectively activatable patch-pump assembly, said patch-pump assembly comprising: •a sealed prefilled drug-reservoir containing a drug to be delivered; •an associated conduit in connection therewith; •a selectively activatable penetrator which penetrates said sealed prefilled drug-reservoir and facilitates drug access to said conduit; and •a selectively activatable, associated, cannula-containing assembly for delivering a drug subcutaneously to a subject, in fluid connection with said conduit; wherein a selective activation-step initiates penetration of said sealed prefilled drug-reservoir, drug access from said drug-reservoir to said conduit, drug access from said conduit to said cannula-containing assembly and delivery from said cannula-containing assembly, thereby being a selectively activatable patch-pump assembly.

Abstract: The invention relates to a pump unit (2), replaceably attachable to a reusable backend (3) of an injection arrangement (1) for delivering a liquid medicament, the pump unit (2) comprising a medicament inlet (2.1), a medicament outlet (2.2) and a peristaltic pump for delivering the liquid medicament from the inlet (2.1) to the outlet (2.2), the peristaltic pump comprising a pump rotor (2.3) and a pump hose (2.4), the pump hose (2.4) partially arranged around the pump rotor (2.3), the pump rotor (2.3) having protrusions (2.5) for engaging the pump hose (2.4), wherein a fixing side (2.6) of the pump unit (2) facing a reusable backend (3) when attached has a recess (2.7) in the shape of a circular arc for allowing a correspondingly shaped stop (3.1) protruding from the reusable backend (3) to enter into the pump unit (2) so as to support the pump hose (2.4) from an outer side opposite the pump rotor (2.3) thus allowing the protrusions (2.5) to locally squeeze the pump hose (2.4) against the stop (3.

Abstract: Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.

Abstract: An arrangement for extracorporeal life support is further developed in such a way that a pump actuating signal produces a wave-like surging and subsiding pump output for a pulsatile flow. The pump is preferably a non-occlusive blood pump, such as a diagonal pump, for example. In a preferred variant of embodiment the control signal is provided by an ECG. This allows the diastolic pressure to be increased in order to improve the oxygen balance of the heart muscle.

Abstract: Titration schemes are carried out by medical infusion devices, such as ambulatory or implantable infusion devices. The titration schemes carried out by infusion systems and devices may take into account patient side effects in controlling the rate at which a medicament is delivered from the devices of systems.

Abstract: An electronic medical system is described. The system comprises an external RF power transmitter configured to emit a first power signal via an electromagnetic coupling, said RF power transmitter being configured to emit said first energy signal with a power no greater than 1W. The system further comprises an implantable medical device comprising: at least one receiver antenna configured to receive said first energy signal via an electromagnetic coupling; an RF power receiver module configured to extract a second energy signal having a power of at least 1 mW and to be powered by said second energy signal; a power actuator module, operatively connected to the RF power receiver module, powered by said second energy signal. The power actuator module is configured to deliver a medical treatment to at least a target tissue of a patient on the basis of a control signal generated by the RF power receiver module.

Abstract: The accuracy of drug delivery with drug pump devices may be improved by a combination of pump operation at high flow resistances and pump pressures, pressure-relief mechanisms, and sensor-based feedback for pump control.

Abstract: Some embodiments of an infusion pump system may include an occlusion sensor that can be used to detect when an occlusion exists in the fluid path between the medicine reservoir and the infusion site on the user's skin. Such an occlusion may occur, for example, when the fluid flow line (e.g., a cannula, infusion set tubing, or the like) is kinked. If the medicine dispensation path to the user is occluded, the user may receive no dosage or a lower dosage of the medicine. As such, the occlusion sensor can be used to indicate when the fluid is flowing or not flowing, thereby permitting the infusion pump system to communicate an alarm to the user if an occlusion exists.

Abstract: A patient care system is configured for infusing fluid to a patient. The system includes at least one fluid infusion pump connected to a respective fluid supply for pumping the contents of a fluid supply to a patient via fluid supply lines. The system includes a programming module that determines the efficiency of the fluid infusion pumps and dynamically adapt the infusion pumps based on one or more system parameters.

Abstract: Valves, valved fluid transfer devices and ambulatory infusion devices including the same.

Abstract: Some embodiments of an infusion pump system may be configured to wirelessly communicate with other devices using near field communication (NFC). In particular embodiments, by incorporating near field communication capabilities into the infusion pump system, user communications with the infusion pump system can be enhanced and simplified.

Abstract: The invention relates to a method for delivering at least one fluid medicament from a medical device. The invention also relates to a medical device. The technical problem of improving the dose accuracy is solved by a method for delivering at least one fluid medicament from a medical device comprising a first reservoir containing a first fluid medicament, a second reservoir containing a fluid, and a fluid element connected to said first reservoir and said second reservoir. The method comprises receiving information about a desired dose of the first fluid medicament to be ejected, adjusting said dose to be ejected from said first reservoir based at least in part on information about a content of said fluid element, and ejecting said adjusted dose from said first reservoir through said fluid element. The technical problem is further solved by a medical device configured to work according to the method.

Abstract: A system for the precise metering and delivery of discrete volumes is described. The system is composed of inexpensive components that can be easily assembled, allowing for cost-effective manufacturing of the system. The system can precisely meter and deliver fluids, solids in particulate or powder form, or alternatively it could mix discrete amounts of fluid and solid. Potential applications for the system and microfluidic device include subcutaneous, long-term, automated drug delivery, such as insulin for diabetics.

Abstract: Some embodiments of an infusion pump system can include a controller in electrical communication with a pump device so as to provide selected dosages of a medicine to a user over a period of time. The infusion pump system can employ a number of power management techniques to reduce the likelihood current drain of a rechargeable battery of the infusion pump system.

Abstract: A drug infusion system includes a first infusion pump including a processor and a user interface in operable communication with the processor, and a second infusion pump, wherein the processor of the first infusion pump (i) enables an operator to make a selection using the user interface, the selection specifying a combination of a plurality of drugs to be delivered to a patient using the first and second infusion pumps, and (ii) commands the first infusion pump to deliver one or more drug of the combination to the patient and the second infusion pump to deliver one or more drug of the combination to the patient.

Abstract: An infusion pump for delivering medicament to a user. The pump comprises a pump mechanism and a bolus program module. The bolus program module is programmed to control the pump mechanism to deliver a bolus. An alarm program module is in data communication with the alarm, the timer, and the bolus program module. The alarm module is programmed to generate an alarm signal when the bolus program module does not control the pump mechanism to deliver a bolus within a predetermined period of time.

Abstract: A cassette has an interface element having a first position and a second position. The interface element is configured to be driven from the first position to the second position and back to the first position by unidirectional rotary motion of a driving element. The cassette also has a first and a second pumping chamber each having a volume and each coupled to the interface element such that the volume of the first pumping chamber is increasing while the volume of the second pumping chamber is decreasing as the interface element moves from the first position to the second position and the volume of the first pumping chamber is decreasing while the volume of the second pumping chamber is increasing as the interface element moves from the second position to the first position.

Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump.

Abstract: An infusion pump comprises a tube attachment section configured such that an infusion tube is detachably attachable to the tube attachment section, an access cover configured to close the tube attachment section in an openable manner, and a tube clamp mechanism located within the tube attachment section and configured to clamp and block a portion of the infusion tube. The tube clamp mechanism comprises a base member, a clip clamp member rotatably mounted on the base member, a tube clamp release lever rotatably mounted on the base member, and a tube clamp member rotatably mounted on the base member.

Abstract: A drug delivery system provides for controlled mixing of drugs, using flow controllers to guide drugs into single or multiple catheters, enabling a single lumen catheter to dispense multiple drugs, diluting a concentrated drug to provide varying drug concentration, using a buffer fluid to deliver precise amounts of drug or to separate drugs within a catheter, and using a patient's bodily fluid as a diluent or buffer fluid. A drug testing/filler apparatus may be used prior to system use to facilitate filling of multiple reservoirs and may also be used for refilling. The system can provide bolus or continuous delivery and enable the measured delivery of drug to selected distal locations at independent rates. New types of catheter systems, catheter hub assemblies, and uses therefore are also described. New methods for promotion of healthy pregnancy and treatment of a developing fetus are disclosed.

Abstract: An anti-free-flow mechanism includes an occluder mechanism which is disposed along a segment of tubing and a mounting structure. The occluder mechanism is normally in a biased closed position, but may be moved into an open position by placement in the mounting structure. However, unless force is applied to keep the occluder mechanism in the mounting structure, the occluder will move relative to the mounting structure and return to the first, closed position.

Abstract: The present invention provides a kit for the delivery a therapeutic agent to an organ blood flow and the removal of the excess of said therapeutic agent from said organ blood flow, said kit comprises: (a) the therapeutic agent, (b) a first retrievable medical device (26), for delivering said therapeutic agent into the organ inflow, (c) a second retrievable medical device for isolating the organ outflow vessel and (d) a separation device (25) comprising at least one filter able to separate the therapeutic agent excess from the organ outflow, having an inlet (38) for the organ outflow having a therapeutic agent excess and an outlet (39) for filtered organ outflow.

Abstract: Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.

Abstract: The invention relates to a liquid storage and delivery system including a reusable control and drive unit (8), a container (2), a pump module (4) fluidically connected to the container (2), and a coupling system (6) configured for removably coupling the pump module (4) to the control and drive unit (6). The pump module comprises a pump engine (20), a pump outlet (22), and a transmission input coupling (18) coupled to the pump engine (20). The control and drive unit (8) comprises a pump drive (34) configured to engage the transmission input coupling (18) of the pump module (4) when the pump module (4) is coupled to the control and drive unit (8). The container (2) is in the form of a flexible pouch and the pump module (4) is permanently integrated with the flexible pouch and forms therewith a disposable unit.

Abstract: A neurosurgical apparatus includes a guide device and a neurosurgical instrument is disclosed. The guide device includes a tube for insertion into the brain and a head attached to the proximal end of the tube for affixing the guide device to a hole formed in the skull. The head has a passageway therethrough in communication with the bore of the tube such that the bore of the tube and the passageway through the head define an internal channel through which a neurosurgical instrument can be passed into the brain of the subject. The neurosurgical instrument is for insertion to a desired brain target through the internal channel of the guide device. The apparatus includes one or more sealing elements for providing a fluid tight seal between the internal channel of the guide device and the exterior of the neurosurgical instrument to prevent fluid leakage from guide tube.

Abstract: A medical device system. The system includes a first medical device, a first remote interface, and a second remote interface in communication with the first remote interface and the first medical device, wherein the first medical device sends a command to the first medical device through the second remote interface, and wherein when the second remote interface receives the command, the command must be confirmed by the second remote interface before the command is send by the second remote interface to the first medical device.

Abstract: A syringe holder includes a body with a syringe retainer, an elongated finger and a stop member connected to the body. The finger inserts longitudinally into a socket on a pump without the aid of tools and permits the holder to move in multiple planes. The stop member limits such movement. The stop member can include a clip for releasably clamping onto a portion of a pump. The syringe retainer can include a hole in the body and may optionally include an adaptor mounted in or extending into the hole for detachably attaching a syringe. The syringe holder can be incorporated into a tube set assembly or an infusion system.

Abstract: The systems, methods and articles described herein are directed to at least one pressure sensor along a downstream fluid line which senses fluid pressure and assists an occlusion detection feature in determining the presence of occlusions in the downstream fluid line. In addition, the system can dynamically adapt the occlusion detection feature based on a delivery of fluid, such as a bolus, in order to prevent the system from creating a false alarm regarding an occlusion of the downstream fluid line.

Abstract: A puncture device includes a puncture needle having a double structure including an outer needle and an inner tube located in the outer needle; a housing unit accommodating the puncture needle; and a puncture mechanism provided within the housing unit. The puncture mechanism includes a push-in unit configured to be pushed in with respect to the housing unit, an outer needle slide unit attached to the outer needle and configured to slide within the housing unit, a stopper providing releasable fixation between the push-in unit and the outer needle slide unit and releasable fixation between the inner tube inserted into the outer needle and the outer needle slide unit, an elastic member, a first end of which is fixed to the housing unit and a second end of which is fixed to the outer needle slide unit, and a fixation release unit configured to release the fixation between the push-in unit and the outer needle slide unit and the fixation between the outer needle slide unit and the inner tube.

Abstract: A removable material is deposited or otherwise applied to a flat substrate surface in a pattern corresponding to desired corrugations in a membrane, e.g., a deflection diaphragm. The applied material serves as a scaffold for a polymeric material, which is applied thereover, and following cure or hardening, the polymeric material is removed to form a finished corrugated membrane.

Abstract: A one-way valve (1) comprises a seat (5) and a membrane (4) having an inner portion (4a) that is stretched over the seat, wherein, in use, the inner membrane portion is selectively deflected from the seat such that a fluid path is created from one side of the membrane to the other so as to open the valve, and wherein an outer peripheral portion (4b) of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion. The one-way valve may be used in a pump for an infusion system.

Abstract: An infusion system comprises an infusion set (30) with one or more advanced features including tube set strain relief (10), infusion pumps having heat exchange abilities and two-direction pumping abilities (100), Piezo pump devices (200), reservoirs (220, 240) made from expanded tubing, and oil impregnated pump plungers (302). An exemplary strain relief (10) includes an adhesive layer (12) such as pressure sensitive adhesive (PSA) secured to a base (14). The base (14) rotatably receives a pin (18) of a tube holder (16). The pin (18) is captured within an opening (22) of the base (14) to allow 360 degree rotation of the tube holder (16).

Abstract: Methods and devices for drug infusion and for storing a drug container. The methods and devices can include ambulatory infusion systems and dosing units. The dosing units can have and an inlet port for attachment to an external liquid drug container, an outlet port, a pump kernel, and a control valve.

Abstract: The present invention includes systems, devices and methods for mechanically interfacing between a pump and an infusion kit or conduit, and methods and materials for producing same. According to some embodiments of the present invention, there may be provided a mechanical pump-tube interface unit adapted to detachably connect to a pump. The mechanical pump-tube interface unit may be adapted to hold a fluid conduit/tube positioned such that when the interface is attached to a pump the pumping mechanism of the pump acts upon the fluid in the tube. A mechanical pump-tube interface unit may include physical adaptations designed to prevent longitudinal and/or rotational movement, in relation to the unit, of a fluid conduit/tube held by or attached to the interface unit. According to further embodiments, a segment of conduit/tube may be attached/connected to a mechanical tube-interface during the assembly of the interface unit, to form one integral unit including the conduit/tube segment secured/trapped within.

Abstract: Methods and systems of catheterization include a flexible catheter adapted for insertion into a heart of a living subject. The catheter has a lumen for passing an electrically conductive fluid therethrough with the fluid exiting the catheter at the distal portion. The lumen is connectable to an irrigation pump to form a fluid communication therewith. A fluid reservoir connected to the lumen supplies the fluid to the catheter. Electrocardiogram circuitry is connectable to the subject for monitoring electrical activity in the heart. An electrically conductive cable diverts induced charges in the fluid from the catheter electrodes, for example by connection to an isolated ground of the electrocardiogram.

Abstract: An infusion device for delivering discrete boluses of medication to a patient, using a mechanically actuated piston. The infusion pump employs a near-field communication system to convey the occurrence of an actuation, the amount of medicament remaining in the pump, and other information to a nearby near-field receiver device. The disclosed drive system and nearer-field communications system provides an infusion device capable of accurately delivering medication and providing a means for tracking and logging data while eliminating the need for a power source within the device, thereby minimizing weight and size.

Abstract: The invention relates to a injection device, comprising a housing being adapted to receive in its proximal housing portion a container with an injection fluid and to receive in its distal housing portion a dose setting and injection mechanism, wherein the mechanism includes a piston rod being axially displaceable with respect to the housing for dispensing injection fluid from the container, wherein the piston rod has an outer thread and is arranged torque proof with respect to the housing, dose setting means comprising a threaded element, which threaded element has an inner thread being in engagement with the outer thread of the piston rod, is designed so that its axial position relative to the housing is changeable and is rotatable relative to the piston rod and relative to the housing during setting of an injection dose, wherein the dose setting means are designed such that the threaded element is held in torque proof manner relative to the piston rod and to the housing during the injection of the beforehan

Abstract: Connectors are attached to a pump housing. The pump squeezes tubing of a particular outer diameter creating a peristaltic contraction of the tubing to push the fluid in the tubing in a particular direction. The connectors hold the tubing in slots having walls that are narrower than the outer diameter of the tubing. To aid in pushing the tubing into the slots, a door is attached to the connectors that pushes the tubing into the slots while closing thereby covering the slots, which helps assure that the tubing is properly attached to the connector. Alternatively, the connector may be permanently attached to the tubing, but may be detached from the pump housing, so that as long as the connectors are connected properly, the tubing is connected properly.

Abstract: A medical syringe pump has a first processor (21) responsible for controlling infusion and a second processor (22) that functions as a watchdog to monitor operation of the first processor. A data communication connector (27) is located in the pump battery compartment (25) so that the batteries (24) have to be removed before external access can be made using an external connector (4). Removing the batteries (24) disables the infusion function of the first processor and ensures that the pump is prevented from infusing medication. When the external connector (4) is connected the first processor (21) can reprogram the second processor (22) or information about historical operation of the pump can be downloaded.

Abstract: Multicomponent infusion device assemblies include locking and unlocking mechanisms that allow for locking and unlocking of components via actions capable of being carried out by at least some patients suffering from movement disorders. Tools or disengagement components may be used to unlock or disengage the components.

Abstract: One embodiment of the present patent application is a syringe infusion pump that includes a syringe, a syringe barrel holder, and a force sensor. The syringe includes a barrel and a plunger. The plunger has a plunger axis and the barrel has a barrel axis and a barrel diameter. The syringe is one of a plurality of syringes, each having a different barrel diameter. The force sensor is positioned for detecting a force along the barrel axis. The syringe holder provides the barrel axis automatically aligned with the force sensor for each syringe of the plurality of syringes.

Abstract: A medical remote controller device is disclosed. The device includes a display and at least one input switch dedicated to bolus delivery wherein a bolus delivery is programmed when the input switch receives an input and wherein the number of inputs received by the input switch determines the amount of bolus to be delivered.