Deformable Resilient Chamber Type Patents (Class 604/153)
  • Patent number: 12017038
    Abstract: Described is a large volume parenteral (LVP) infusion device system including a cassette and a pump. The system can include means for sensing pressure in a pump having a symmetric or matched, parallel dual chamber pumping mechanism and an attached cassette. The system can include a cassette having dual pumping chambers and a distal fitment, the distal fitment having an outlet port configured for attachment to tubing for infusion administration and being disposed on a distal end of the cassette, the distal fitment further including opposing cutouts. The system can also an air in line sensor, the AIL sensor configured to bracket the distal fitment at the position of the cutout when the cassette is loaded on the pump. The cassette can be mechanically coupled to the pump. The cassette can include a user actionable flow stop. The system can be configured for cassette misload protection.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: June 25, 2024
    Assignee: Altra, Inc.
    Inventors: Matthew G. Morris, Jr., Marco A. Schilling
  • Patent number: 12016986
    Abstract: A blood purification apparatus includes: a peristaltic pump that includes a stator to which a pump tube including a first portion and a second portion is detachably attached, and a rotor including a roller and a guide portion, the roller delivering liquid by squeezing the pump tube, the guide portion retaining the pump tube so that the pump tube is squeezable with the roller about a predetermined axis; an anchor member that anchors an attaching member to which the pump tube is attached; and a displacing portion that displaces the attaching member between a set position and an unset position by moving the anchor member with the attaching member being anchored by the anchor member.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: June 25, 2024
    Assignee: Nikkiso Company Limited
    Inventors: Yuki Eda, Masaaki Ohta
  • Patent number: 11992862
    Abstract: A cleaning device and a cleaner are provided. The cleaner includes the cleaning device and at least one liquid storage device. The cleaning device includes an outer housing, at least one first connecting component, a liquid spraying structure, and a liquid driving structure. The outer housing includes a liquid inlet and a liquid outlet. First connecting components having different structures and liquid storage devices having different structures are provided, one of the first connecting components is matched with a corresponding one of the liquid storage devices, and the one of the first connecting components matched with the corresponding one of the liquid storage devices is connected to the outer housing. The outer housing is connected to the first connecting components having different structures to connect to the liquid storage devices having different structures.
    Type: Grant
    Filed: December 5, 2023
    Date of Patent: May 28, 2024
    Assignee: DONGGUAN AISI HEALTH PRODUCTS CO., LTD.
    Inventor: Biao Zhou
  • Patent number: 11951084
    Abstract: The present application discloses a composition for the treatment of Painful Damaged Disc Syndrome (PDDS), disc bulge, protrusion and herniation, and a delivery method and recommended treatment protocol for delivering thereto to a subject with an effective dosage of the composition. The composition has anti-inflammatory, antioxidant and vasodilating and antispasmodic properties. The compound is being administered via intravenous drip over a specified period for pain relief.
    Type: Grant
    Filed: April 28, 2023
    Date of Patent: April 9, 2024
    Assignee: Progressive Health Partners
    Inventors: Mark James Bartiss, Daniel Bies, Dianne Dalton
  • Patent number: 11892108
    Abstract: A lever including a far end to engage an infusion tubing is provided. The lever includes a pivot end configured to fit into a shaft and to allow the lever to rotate about a shaft axis, the pivot end including a pocket to capture a spring having a leg protruding outside. The spring is configured to apply a bias from the lever against a door assembly. The lever includes a tab disposed on an outer side of the far end and configured to interface with the door assembly, and a pusher protruding into an inner side of the far end and configured to contact the infusion tubing when the far end engages the infusion tubing. The pusher applies a downward pressure to the infusion tubing when the door assembly is closed until the infusion tubing is properly aligned with an air-in-line sensor disposed on both sides of the tubing.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: February 6, 2024
    Assignee: CAREFUSION, 303, INC.
    Inventor: Steve Roberts
  • Patent number: 11839741
    Abstract: An apparatus, system and method for regulating fluid flow are disclosed. An apparatus for infusing fluid into a patient infusion apparatus includes a drip-chamber seat configured to receive a drip chamber; a tube seat configured to receive a tube fluidly coupled to the drip chamber, the tube including a plurality of conduits for fluid flow therethrough; a plunger configured to engage with the tube; and a user actuator configured to actuate the plunger.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: December 12, 2023
    Inventors: Christopher C. Langenfeld, Daniel B. Finnegan, Dean Kamen, James M. Scott
  • Patent number: 11828280
    Abstract: A pump for use with a tube, having a rotor having an axis of rotation and a plurality of rollers configured to define an orbital path about the axis of rotation, the orbital path defined by a radius, and a roller bed having a surface adapted to support the tube for peristaltic compression by one or more rollers, wherein the surface has a predetermined profile comprising a circular arc segment and at least one side segment, the arc segment having a first curvature defined by the radius, and the at least one side segment having a second curvature lesser than the first curvature.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: November 28, 2023
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Itzhak Fang, Andrei Szilagyi, Alexander Lifshitz, Jack Walker, Sean Yasuo Sullivan
  • Patent number: 11780752
    Abstract: An ion-exchange resin regeneration system includes: salt water flowing means that flows an aqueous sodium chloride solution or an aqueous potassium chloride solution into a container storing ion-exchange resin; and hard water component crystallizing means that crystallizes and removes hard water components containing metal ions from drained water arising from the ion-exchange resin through which the aqueous sodium chloride solution or the aqueous potassium chloride solution has flowed.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: October 10, 2023
    Assignee: Panasonic Intellectual Property Management Co., Ltd.
    Inventors: Yasunari Maeda, Tomohiro Akita, Ayane Takehisa
  • Patent number: 11759565
    Abstract: A drug delivery device includes a housing defining a shell, a container, a drive mechanism, a needle assembly having first and second ends, a fluid flow connection, and a flow adapter, each of which is at least partially disposed within the housing. The container has first and second ends and an inner volume to contain a medicament to be administered to a user. The drive mechanism is adapted to exert a force to urge the medicament out the second end of the container. The fluid flow connection is coupled to the second end of the container and the first end of the needle assembly and is adapted to allow the medicament to flow from the container to the needle assembly. The flow adapter includes at least one protrusion for generating a minor head loss to the medicament flowing within the fluid flow connection and helps to reduce variations of injection rates due to variations in drug product viscosities.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: September 19, 2023
    Assignee: AMGEN INC.
    Inventors: Carl Conrath, Ali Nekouzadeh, Basel Hasan Taha
  • Patent number: 11712512
    Abstract: A low-cost medical pump for ambulatory use provides an improved IV line cartridge attachment allowing for single handed, low force release while preventing inadvertent IV line cartridge release. A rotatable side lever minimizes the force required to move the locking elements against a spring biased force urging the locking elements to a locking position.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: August 1, 2023
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Zhenhua Mao, Frederick Lee, Mei Zhang
  • Patent number: 11701464
    Abstract: A substance delivery device engages with a reservoir, and includes a pump that draws therapeutic substance from the reservoir into a pump chamber of the delivery device without changing the internal dimensions of the reservoir. The volume of the therapeutic substance within the pump chamber varies in response to changes in the internal dimensions of the pump chamber. An orientation sensor generates an output indicating an orientation of the delivery device with respect to gravity. Control circuitry drives the pump to: calculate a volume of the substance within the reservoir, draw the substance into the pump chamber in response to (i) the calculated volume, in combination with (ii) an output from the orientation sensor that the delivery device is in an orientation that allows the substance to be drawn from the reservoir, and deliver the substance from the pump chamber to the subject. Other applications are also described.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: July 18, 2023
    Assignee: EITAN MEDICAL LTD.
    Inventors: Andrei Yosef, Shaul Eitan, Boaz Eitan, Ori Ben-David
  • Patent number: 11635073
    Abstract: An improved linear peristaltic pump that is able to be manufactured using fewer parts while also improving the performance and the reliability of the pump. The linear peristaltic pump utilizes a leaf spring in direct contact with a tube and is therefore able to provide smooth transitions in the forces exerted on the tube.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: April 25, 2023
    Inventor: John Patrick Miller
  • Patent number: 11617832
    Abstract: Embodiments include methods and systems for maintaining glucose homeostasis. Systems can include a pump, a first reservoir including a homeostasis agent, an umbilical catheter capable of being advanced in the umbilical vein or in the falciform ligament, and a sensor. Systems can also include a biocompatible coating, a microprocessor in communication with the pump and the sensor, and a power supply. Methods can include implanting a pump and reservoir subcutaneously in a patient, advancing a catheter in the umbilical vein or in the falciform ligament, measuring a blood glucose level, pumping a homeostasis agent, and administering the homeostasis agent to the portal venous system.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: April 4, 2023
    Assignee: International Business Machines Corporation
    Inventor: Amos Cahan
  • Patent number: 11464904
    Abstract: Systems and methods for controlling fluid delivery via a manually administrable medication container to a patient through a fluid delivery pathway are provided. The systems and methods described herein incorporate rules-based clinical decision support logic to drive a flow control valve within a flow pathway based on a determination of whether or not an IV fluid connected to an input port on the pathway is appropriate for patient administration by considering such factors as patient-specific clinical circumstances, current medical orders, and accepted delivery protocols. Related apparatus, systems, methods and articles are also described.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: October 11, 2022
    Assignee: CRISI Medical Systems, Inc.
    Inventors: Stephen M. Prince, Walter J. Bochenko, Winthrop De Childers
  • Patent number: 11371498
    Abstract: A fluid-handling cassette comprising a plurality of diaphragm valves and pumps is configured to have its actuation ports located along a thin or narrow edge of the cassette. Actuation channels within the cassette lead from the actuation ports to actuation chambers of the valves and pumps in a space between plates that comprise the cassette. The individual plates have a nominal thickness that is sufficient to provide a rigid ceiling for the actuation channels, but sufficiently thin to minimize the overall thickness of the cassette. The cassette can be plugged into or unplugged from an actuation receptacle or a manifold by its narrow edge. A plurality of such cassettes can be stacked together or spaced apart from each other to form a cassette assembly, providing for a convenient way to install and remove the cassette assembly from its actuation receptacle.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: June 28, 2022
    Assignee: DEKA Products Limited Partnership
    Inventors: Kevin L. Grant, Benjamin E. Colburn, Joseph M. Rauseo, Benjamin J. Doucette, Marc J. Gorayeb
  • Patent number: 11331002
    Abstract: A system and method for collecting operation data associated with a medical apparatus including an internal device implanted in a subject and an external device that is magnetically-coupled to and drives the internal device. The medical apparatus may be monitored to obtain raw data associated with the operation of the medical apparatus and one or more calculations may be performed on the raw data, wherein the raw data and/or calculated values may be associated with voiding frequency and voiding volume of the subject. A report may be generated from the raw data and/or calculated values. In addition, one or more signals may be sent to the external device and/or a docking station, or communicated by other means, to indicate to the subject that the operation of the medical apparatus should be altered.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: May 17, 2022
    Assignee: Vesiflo, Inc.
    Inventors: Kevin M. Connolly, Terence M. Moore, Jean-Marc Gery
  • Patent number: 11331248
    Abstract: A bioprocess vessel includes a flexible bag or substantially rigid container that defines an interior volume and having a bottom surface, the bottom surface being open or containing an aperture therein for the passage of fluid. A pump is secured to the bottom surface of the flexible bag or substantially rigid container. In some embodiments is secured directly to the flexible bag or substantially rigid container. In other embodiments, the pump is secured indirectly the flexible bag or substantially rigid container using, for example, a port that extends through the aperture on the bottom surface. The port or flanged surface may also be integrated into the pump, which is secured to the vessel. An optional mixing adaptor may be provided inside the interior volume of the flexible bag or substantially rigid container and at least partially covers the inlet that leads to the pump.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: May 17, 2022
    Assignee: ALPHINITY USA, INC.
    Inventor: Michael C. Gagne
  • Patent number: 11278680
    Abstract: A medical fluid infusion system includes a pump system configured to deliver a fluid drug to a patient. The system includes a pump, such as a piston pump, for driving fluid to a patient. One or more pressure sensors are configured to measure and detect changes in fluid pressure in a fluid flow line of the infusion system. The changes in fluid pressure, when detected, can be an indication of proper or improper functioning of a valve system of the pump system of the fluid infusion system.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: March 22, 2022
    Assignee: CareFusion 303, Inc.
    Inventors: Daniel Kimm, Lee Good, Alexander Ellington
  • Patent number: 11260170
    Abstract: The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising: a disposable injector (60) comprising an injection needle (65), a flexible tube (64) and an injector fluid coupling (68), wherein the injection needle (65) is in fluid communication with the fluid coupling (68) via the flexible tube (64), a disposable cartridge (70) comprising a reservoir (80) at least partially filled with the liquid medicament and comprising a cartridge fluid coupling (90) in fluid communication with the reservoir (80), wherein the injector (60) and the cartridge (70) are mechanically interconnected in an undeployed configuration (4), in which the injector fluid coupling (68) and the cartridge fluid coupling (90) are disconnected, and—wherein the cartridge (70) is displaceable relative to the injector (60) into a deployed configuration (6), in which the injector fluid coupling (68) and the cartridge fluid coupling (90) are in fluid com
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: March 1, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Olaf Zeckai, Meinolf Werner
  • Patent number: 11160928
    Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: November 2, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 11141528
    Abstract: An external medical device includes a first cartridge bay with a first cartridge port, a second cartridge bay with a second cartridge port, a fluid outlet in fluid communication with the first cartridge port, a fluid pump configured to deliver a therapeutic fluid from a fluid cartridge engaged with the first cartridge port through the fluid outlet in response to fluid outlet control signals, a fluid inlet in fluid communication with the second cartridge port, and a fluid control structure in fluid communication with the fluid inlet to control fluid flow through the fluid inlet.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: October 12, 2021
    Inventors: Thomas Leroy Schmitz, Jesse James Corry
  • Patent number: 11097069
    Abstract: A pump cassette body for detecting air bubbles in a fluid pathway, comprises an upstanding flow director vane, a fitment integrally molded into the pump cassette body, wherein the fitment comprises a base integrally molded into the pump cassette body, an elastomeric member attached to the base, and a housing at least partially surrounding the elastomeric member, wherein the elastomeric member is co-molded to the housing.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: August 24, 2021
    Assignee: CAREFUSION 2200, INC.
    Inventor: Daniel Abal
  • Patent number: 11077249
    Abstract: The systems, methods and articles described herein are directed to at least one pressure sensor along a downstream fluid line which senses fluid pressure and assists an occlusion detection feature in determining the presence of occlusions in the downstream fluid line. In addition, the system can dynamically adapt the occlusion detection feature based on a delivery of fluid, such as a bolus, in order to prevent the system from creating a false alarm regarding an occlusion of the downstream fluid line.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: August 3, 2021
    Assignee: Carefusion 303, Inc.
    Inventors: Donald Halbert, Jesse Guerra, Stephen Bollish
  • Patent number: 11065153
    Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: July 20, 2021
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: John I. Muri, Craig Edwards
  • Patent number: 10967122
    Abstract: Abstract of the Disclosure Implantable drug delivery devices and methods of making and using the same are provided. The implantable drug delivery devices permit selective activation and deactivation of drug delivery while subcutaneously implanted in a patient without the use of electronic equipment or power. The devices include a bistable member that has two stable states. In a first stable state, the bistable member does not close off a fluidic pathway between a drug reservoir and a drug release aperture, thereby allowing drug release from the device. In a second stable state, the bistable member closes off or narrows the fluidic pathway, thereby reducing or preventing drug release from the device. A patient or another person can reversibly change the bistable member between the first and second stable states by applying pressure on the patient's skin over the site of implantation and/or manipulating the device through the patient's skin at the site of implantation.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: April 6, 2021
    Assignee: Massachusetts Institute of Technology
    Inventor: Michael J. Cima
  • Patent number: 10959881
    Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: March 30, 2021
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: John I. Muri, Craig Edwards
  • Patent number: 10894123
    Abstract: The invention generally provides a fluid delivery system comprising: a reservoir (7); a pumping chamber (8) having a volume, an inlet valve (48), an outlet valve (49) and a membrane (47); an actuator (20); and a drive member (21). The inlet valve and the outlet valve each comprise a passive normally closed one-way check valve. The inlet valve provides selective fluid communication between the pumping chamber volume and the reservoir. Fluid in the reservoir is at substantially ambient pressure. The drive member is operatively coupled to the pumping chamber membrane. Energising the actuator moves the drive member in reciprocating motion and thereby displaces the membrane to change the pumping chamber volume between a minimum volume and a maximum volume. The pumping chamber volume is held at a pressure above the ambient pressure in the reservoir when the actuator is at rest.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: January 19, 2021
    Assignee: VICENTRA B.V.
    Inventors: Timothy William Oakes, Joseph Cefai
  • Patent number: 10894132
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: January 19, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 10821231
    Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: November 3, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 10716584
    Abstract: A fluid management system for use in a tissue resection procedure includes a controller. An inflow pump is operated by the controller and configured to provide fluid inflow through a flow path to a site in patient's body. An outflow pump is operated by the controller and configured to provide fluid outflow through a flow path from the site in patient's body. A motor driven resecting device may be provided for resecting tissue at the site. The controller is configured to actuate an inflow pump and an outflow pump in response to various signals and various algorithms are provided to provide malfunction warnings and assure safe operation.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: July 21, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Aaron Germain, Kyle Klein, Michael D. Walker, Robin Bek
  • Patent number: 10682461
    Abstract: A pumping chamber (8) for a micro-pump (2), the pumping chamber having a volume of 100 micro litres or less bounded by an interior wall and having an inlet (87) and an outlet (88), wherein the interior wall has at least one inwardly projecting rib (70) having a first end adjacent the inlet and a second end adjacent the outlet.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: June 16, 2020
    Assignee: VICENTRA B. V.
    Inventor: Timothy William Oakes
  • Patent number: 10606059
    Abstract: In some instances, an apparatus can include a light sensitive imaging sensor having a surface to receive a fluid sample, a body to be moved relative to the light sensitive imaging sensor and having a surface to touch a portion of the fluid sample, and a carrier to move the body toward the surface of the light sensitive imaging sensor to cause the surface of the body to touch the portion of the fluid sample, so that as the surface of the body touches the portion of the fluid, the surface of the body (i) is parallel to the surface of the light sensitive imaging sensor, and (ii) settles on top of the fluid sample independently of motion of the carrier.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: March 31, 2020
    Assignee: Alentic Microscience Inc.
    Inventor: Alan Marc Fine
  • Patent number: 10578474
    Abstract: Various systems and methods for detecting air in a chamber of an infusion system are disclosed. In one embodiment, a determination is made that air is contained in the chamber on the basis of a change in the average force exerted against the plunger utilizing a derivative spike for event detection and a systematic reduction in the average force to confirm the nature of the change. In another embodiment, a determination is made that the chamber contains air when a difference between the current force profile and a baseline force profile crosses a threshold. In an additional embodiment, a force profile is classified as being an air force profile or a liquid force profile based on extracted features of the force profile.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: March 3, 2020
    Assignee: ICU Medical, Inc.
    Inventors: Timothy L. Ruchti, Brian G. Markey, Anatoly S. Belkin, Paul T. Kotnik, Mohammad M. Khair
  • Patent number: 10420890
    Abstract: An assembly for a drug delivery device includes a first member and an attenuation member. The first member includes a main body and an elastically displaceable feature connected to the main body. The attenuation member mechanically cooperates with the elastically displaceable feature to influence the force which has to be exerted on the elastically displaceable feature to displace the elastically displaceable feature elastically with respect to the main body. An attenuation member can be used in a drug delivery device to tune the force required to elastically displace an elastically displaceable feature of a first member of the drug delivery device by bringing the attenuation member into mechanical cooperation with the elastically displaceable feature.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: September 24, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Jugl, Axel Teucher
  • Patent number: 10406292
    Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove and a helical spline. The inner housing helical spline guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: September 10, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: David Plumptre
  • Patent number: 10349968
    Abstract: A cartridge includes an electrical connection assembly, a first port, a second port, a pumping mechanism, a valve, and a fluid flow sensor. The electrical connection assembly is configured to electrically couple to an electrosurgical unit. The first port is configured to fluidly couple to a fluid source. The second port is configured to fluidly and electrically couple to a surgical instrument. The pumping mechanism is disposed between the first and second ports and is configured to draw fluid from the fluid source and pump the fluid to the surgical instrument. The valve is disposed between the first and second ports and is configured to selectively obstruct the flow of the fluid therethrough. The fluid flow sensor is disposed between the first and second ports and is configured to sense fluid flow therethrough. The fluid flow sensor is configured to electrically communicate with the electrosurgical unit.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: July 16, 2019
    Assignee: COVIDIEN LP
    Inventor: Daniel A. Friedrichs
  • Patent number: 10219814
    Abstract: An aspiration system including a housing containing an aspiration pump, a chamber, a collection bag in fluid communication with the chamber, and a tubing assembly including a first tube portion connected to the chamber. The tubing assembly has a connector to split the first tube portion into a second and third tube portion, the second tube portion in fluid communication with a first catheter to aspirate particles through the first catheter and the third tube portion in fluid communication with a second catheter to aspirate particles through the second catheter.
    Type: Grant
    Filed: November 22, 2014
    Date of Patent: March 5, 2019
    Assignee: Rex Medical, L.P.
    Inventors: Daniel Stephen Feltyberger, Marc-Alan Levine
  • Patent number: 10219938
    Abstract: Eliminating leaks of molded fluid channels by providing a front housing, rear housing, and a gasket, wherein the front housing has one or more molded fluid channels and one or more seal channels, and wherein at least a portion of the gasket is located between the front and rear housing; molding the gasket onto the rear housing to create a single unit, wherein the gasket has one or more seal lips configured and dimensioned to couple with the one or more seal channels; and assembling the front housing to the rear housing having the gasket, wherein the one or more seal lips couple with the seal channels. A surgical cassette manifold having a front and rear housing, and a gasket therebetween. The front housing having molded fluid channels that mate with the gasket and the gasket having multiple valves and a sensor/diaphragm accessible through the rear housing.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: March 5, 2019
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: Mark W. Ross, James B. Gerg
  • Patent number: 10201661
    Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set a delivery dose. An injector may include a housing, a cartridge containing a medicinal product, the cartridge being retained within the housing, a dose setting mechanism to select a dose of the medicinal product to be expelled, and a dose delivery mechanism to expel the selected dose of the medicinal product. The housing may be a unitary housing within which the dose setting mechanism and the dose delivery mechanism are moveably retained.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: February 12, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
  • Patent number: 10124095
    Abstract: A fluid delivery system, method, and apparatus for providing instillation therapy with a negative-pressure source is described. The apparatus includes a housing having an ambient chamber and a negative-pressure chamber fluidly isolated from each other. The apparatus also includes a moveable barrier disposed in the housing between the ambient chamber and the negative-pressure chamber. The moveable barrier is operable to move between a charge position and a discharge position in response to negative pressure. A fluid source is disposed in the negative-pressure chamber and is collapsible in response to movement of the moveable barrier to the discharge position. The apparatus also includes a fluid outlet in fluid communication with the fluid source, a negative-pressure port in fluid communication with the negative-pressure chamber and configured to be coupled to a negative-pressure source, and a vent formed in the housing and fluidly coupled to the ambient chamber.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: November 13, 2018
    Assignee: KCI Licensing, Inc.
    Inventors: Christopher Brian Locke, James A. Luckemeyer, Timothy Mark Robinson
  • Patent number: 10058659
    Abstract: A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: August 28, 2018
    Assignees: Terumo Corporation, Sanofi-Aventis Deutschland GMBH
    Inventor: Masaru Saiki
  • Patent number: 9968739
    Abstract: A pump cassette includes fluid lumen adapted for passage of an infusion fluid toward a patient. A rotary valve assembly can be actuated to regulate fluid flow through the fluid lumen and a frame is coupled to the fluid lumen and the valve assembly. The frame is adapted to be inserted into a seat of a pump device, wherein the frame provides a platen relative to the fluid lumen. The frame is configured to be inserted into the seat only when aligned in a predetermined orientation relative to the seat.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 15, 2018
    Assignee: CareFusion 303, Inc.
    Inventors: Chris Zollinger, Daniel Abal
  • Patent number: 9937290
    Abstract: A wearable, self-contained drug infusion device is disclosed that is capable of achieving the precise flow rate control needed for dose-critical drugs such as insulin. In preferred embodiments of the device, at least two flow channels are utilized in conjunction with a series of valves for providing a user with selectable, constant flow rate control. The device can be made with small dimensions so that it can be worn by the user with a minimum of discomfort and inconvenience. In addition, the simple mechanical nature of the device provides the user with close control over the flow rate, which is required for safe and effective delivery of insulin and other drugs. Also, the absence of electronic components allows the device to be manufactured inexpensively. The device is provided with a first channel that is long and narrow, functioning as a flow restrictor. The first channel is preferably provided in a serpentine pattern.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: April 10, 2018
    Assignee: Becton, Dickinson and Company
    Inventors: Robert I. Connelly, Kenneth G. Powell
  • Patent number: 9867928
    Abstract: The invention relates to a device (1) for use in eye surgery, comprising a container (9) with fluid (5) which is connected via an irrigation line (12) to a surgical handpiece for delivering the fluid (5) for rinsing an eye (3) on which surgery has been performed, wherein a pillar (8), which in particular is electrically adjustable in its height, is provided for supporting the container (9) and for adjusting the height (H) between the container (9) and the surgical handpiece, and wherein a control for adjusting the height of the pillar (8) is provided in order to deliver the fluid (5) from the surgical handpiece into the eye (3) at an irrigation pressure predetermined by the surgeon, wherein pressurizing means (10) are provided which are designed for charging the fluid (5) to be delivered from the container (9) to the irrigation line (12) with an atmospheric overpressure (PATÜ) and wherein the control for adjusting the desired irrigation pressure is designed both for adjusting the height (H) of the pillar (8)
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: January 16, 2018
    Assignee: EOS GMBH
    Inventor: Manfred Klomp
  • Patent number: 9839373
    Abstract: A system and method for collecting operation data associated with a medical apparatus including an internal device implanted in a subject and an external device that is magnetically-coupled to and drives the internal device. The medical apparatus may be monitored to obtain raw data associated with the operation of the medical apparatus and one or more calculations may be performed on the raw data, wherein the raw data and/or calculated values may be associated with voiding frequency and voiding volume of the subject. A report may be generated from the raw data and/or calculated values. In addition, one or more signals may be sent to the external device and/or a docking station, or communicated by other means, to indicate to the subject that the operation of the medical apparatus should be altered.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: December 12, 2017
    Assignee: Vesiflo
    Inventors: Kevin M. Connolly, Terence M. Moore, Jean-Marc Gery
  • Patent number: 9789255
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case arranged to be held by a user, a tubular chassis telescoped in the case and biased against the case so as to protrude from the case. The injector also includes a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe. A trigger button is distally arranged in or on the case, wherein the trigger button is initially coupled to the case in a manner to protrude distally from the case and interlocked to the chassis in a manner preventing the trigger button from disengaging the case.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: October 17, 2017
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 9750900
    Abstract: A metered liquid droplet inhaling device includes a chassis; a holder releasably connected to the chassis; a container in the holder having a chamber for a composition, an opening for expelling the composition, and a piston; a dose knob accessible outside the chassis for setting a dose to be expelled by accumulating a rotational force; a power supply mechanism for converting the rotational force into an axial force applied to the piston; an activation device connected to the power supply mechanism; a mouth piece connected to the container holder and having a mouth engaging area and an air opening; a droplet generator arranged in the mouth piece and having a plurality of through passing orifices in fluid communication with the opening of the container and with the mouth piece; and a rotation damping member connected to the power supply mechanism for damping an initial pressure peak inside the container.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: September 5, 2017
    Assignee: SHL Group AB
    Inventors: Lennart Brunnberg, Martin Karlsson, Nils Ronquist
  • Patent number: 9636280
    Abstract: The programmable nursing bottle includes a first housing member configured to hold a liquid therein, a second housing member removably attached to the first housing member and a tube member extending from the first housing portion through the second housing portion. The second housing member includes a pump assembly, a programmable control assembly including an interface, a controller operatively connected to the pump assembly, and a sliding door member provided about the second housing member. The door is configured to slide from a first position in which the interface is exposed to a second position in which the interface is covered.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: May 2, 2017
    Inventor: Fatemah Salem Althallab
  • Patent number: 9623182
    Abstract: A medicament delivery device includes a generally elongated tubular housing having opposite proximal and distal parts; a needle shield sleeve slidably and coaxially arranged inside the housing with a proximal part of the sleeve protruding a distance outside the proximal part of the housing; a syringe carrier mechanism having a syringe carrier slidably and coaxially arranged within the needle shield sleeve, a syringe having a stopper, a medicament, and a needle, the syringe being coaxially arranged within the syringe carrier; and a holding member connected to the syringe carrier; a first activator member an a second activator member; a drive mechanism adapted to accumulate a drive force for moving the syringe carrier mechanism in a first step and a second step. The second activator member is arranged within an information device for producing audible, visual, and/or tactile feedback to a user about a completed injection.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: April 18, 2017
    Assignee: SHL Group AB
    Inventor: Oscar Alexandersson
  • Patent number: 9597460
    Abstract: A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: March 21, 2017
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: Masaru Saiki