Abstract: The systems, methods and articles described herein are directed to at least one pressure sensor along a downstream fluid line which senses fluid pressure and assists an occlusion detection feature in determining the presence of occlusions in the downstream fluid line. In addition, the system can dynamically adapt the occlusion detection feature based on a delivery of fluid, such as a bolus, in order to prevent the system from creating a false alarm regarding an occlusion of the downstream fluid line.

Abstract: A peristaltic pump squeezes a hose between squeezing rollers and a counter bearing to move fluid through the hose. To compensate for production tolerances and non-uniformities in hose thickness, and to also keep the mechanical loading of the hose as low as possible during the operation of the pump, the spacing between the squeezing rollers and the active surface of the counter bearing can be varied. The counter bearing has a conical or cone-shaped adjusting surface which is supported against a complementarily shaped support surface on the pump housing. The spacing between the squeezing elements and the active surface of the counter bearing can be adjusted by moving the counter bearing relative to the support surface.

Abstract: An apparatus for brewing a beverage has a base arranged to sit on a support surface with the water and ingredients in an upper urn portion until brewed following which the liquid is discharged from the urn through a filter and into a tube passing through the base into a receptacle. A valve in the form of pinch member acting on the tube closes the tube and is released to discharge the beverage by a movable plate mounted on the base and actuated by placing the base on a receptacle. The urn is formed as a separately molded piece from glass so that it is more hygienic than the plastic material of the base. The bottom of the urn fits into a receptacle in the base with a disk shaped seal connecting to the tube.

Abstract: Apparatus for the treatment of the blood, comprising at least one pump (25, 26, 27), matchable with a corresponding portion of tube (35, 36, 37) supported by a cartridge or module (3) which is associated to the apparatus (1), characterized in that it comprises a pump capable of reducing the pressure inside the chamber defined by the association of the cartridge (3) to the apparatus (1).

Abstract: An infusion system includes a double action infusion pump. The pump includes a cylinder and a reciprocating piston received within the cylinder, the reciprocating piston separating a first pump chamber from a second pump chamber of the cylinder. A reciprocating motor is coupled with the reciprocating piston, and the first and second pump chambers alternate between filling and evacuating conditions with reciprocation of the reciprocating piston through operation of the reciprocating motor, and the speed of reciprocation is varied to provide a continuous output of fluid between the first and second pump chambers. A fluid source and a catheter are optionally coupled with the double action infusion pump. The catheter includes one or more infusion ports near a catheter distal portion, and the one or more infusion ports receive and expel the continuous output of fluid from the double action infusion pump.

Abstract: Apparatus for gas delivery (10), particularly at low pressure and volume. The apparatus has a gas reservoir, a delivery line between the gas reservoir (14) and a gas outlet (68) and a first supply line between a first inlet connect able to a first gas supply and the gas reservoir. A pressure control line is provided with an inlet connect able to a second gas supply. The pressure control line is coupled to the gas reservoir to thereby control the pressure in the gas reservoir.

Abstract: An improved elastomeric pump for an infusion assembly. The pump includes a generally cylindrical mandrel body with first end, an opposed second end, a length, an outer diameter corresponding to a first radius (Rmandrel), a central bore extending through the length, a first port extending from the outer diameter to the bore to provide a fluid passageway, a fill port and an exit port in fluid communication with the bore. The pump includes an inflatable elastomeric tube disposed concentrically about the mandrel, the tube being sealingly secured on the mandrel near the respective ends of the tube and having an original inner diameter that corresponds to a second radius (r) so that it approximately matches the outer diameter of the mandrel (Rmandrel), a length (L) less than the length of the mandrel, a wall thickness (t) such that: (0.4225×r)<t?(0.660×r).

Abstract: The present invention involves, in some embodiments, systems and methods involving fluid handling apparatus for pumping fluid to and from a patient, which may include a reusable component and a disposable pumping cartridge. The reusable component may comprise a control chamber and a pressure transducer configured to measure a gas pressure associated with the control chamber, as well as a processor. The processor may be configured to supply the control chamber with a gas at a predetermined pressure, monitor the gas pressure associated within the control chamber with the pressure transducer over a predetermined period of time, and determine if the change in gas pressure associated within the control chamber exceeds a maximum allowable predetermined limit.

Abstract: An improved elastomeric pump for an infusion assembly. The pump includes a generally cylindrical mandrel body with first end, an opposed second end, a length, an outer diameter corresponding to a first radius (Rmandrel), a central bore extending through the length, a first port extending from the outer diameter to the bore to provide a fluid passageway, a fill port and an exit port in fluid communication with the bore. The pump includes an inflatable elastomeric tube disposed concentrically about the mandrel, the tube being sealingly secured on the mandrel near the respective ends of the tube and having an original inner diameter that corresponds to a second radius (r) so that it approximately matches the outer diameter of the mandrel (Rmandrel), a length (L) less than the length of the mandrel, a wall thickness (t) such that: (0.4225×r)<t?(0.660×r).

Abstract: An apparatus and method are disclosed for providing a continuous and controlled flow of a fluid and/or gas or combination of them when using an irrigation system; said system comprises: a reservoir system comprising a plurality of containers of fluid; said containers in said reservoir system are disposed in a predetermined configuration; a fluid transfer system in fluid connection with said reservoir system, said fluid transfer system comprising: at least one fluid transfer head, adapted to transfer fluid from one of said plurality of containers to an external tubing system; wherein each of said fluid transfer heads is characterized by a mechanism adapted to radially or linearly move each of said fluid transfer heads.

Abstract: A fluid delivery system that includes an infusion pump and a cassette (1) with tubing (75) that is configured for engaging the pump mechanism of the infusion pump to accurately and repeatably deliver a fluid to a subject. The cassette has a housing with first and second ends for holding flexible tubing through which the fluid is directed, and the tubing engages a pumping mechanism to provide movement of the fluid through the tubing. When engaged with the pumping mechanism, the length of tubing is accurately and repeatably positioned in contact with and between the curved wall and the pumping mechanism.

Abstract: A device for regulating cerebrospinal fluid in a cerebrospinal fluid space includes a cerebrospinal conduit having a distal end for insertion into the cerebrospinal fluid space in fluid communication with the cerebrospinal fluid. An actively oscillatably changeable sealed fluid volume can be in fluid communication with the cerebrospinal conduit. The changeable sealed fluid volume can be in a sealed fluid path extending to the distal end of the cerebrospinal conduit and is capable of actively oscillating in a changing fluid volume size for oscillating the cerebrospinal fluid in and out of the distal end of the cerebrospinal conduit and cerebrospinal fluid space.

Abstract: In a fluid transport apparatus, there are cases where a set fluid discharge amount cannot be accurately discharged, due to wear and tear on an elastic tube. Therefore, in a fluid transport apparatus including a fluid transport cartridge and a fluid transport driving unit that are separable from each other, the fluid transport cartridge comprises an elastic tube that transports fluid, a pressing portion that moves between a first position in which a transport path of the fluid is constricted by pressing on the elastic tube from outside and a second position in which the transport path of the fluid is not constricted, and a housing portion that houses a drive mechanism for moving the pressing portion.

Abstract: A medical fluid delivery cassette configured for use with a medical fluid pumping system. The cassette includes a base, a membrane attached to the base, and an adhesive disposed on a portion of the membrane overlying a fluid pump chamber of the cassette. The portion of the membrane overlying the fluid pump chamber is moveable such that the volume of the fluid pump chamber can be changed.

Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a pressure source engageable with the reservoir. The pressure source is movable between a first configuration and a second configuration wherein the pressure source exerts a pressure on the reservoir to urge the drug therefrom. An output conduit is provided for transmitting the drug into the individual. An actuation mechanism is operatively connected to the pressure source and the output conduit. The actuation mechanism is movable between a non-actuated position and an actuated position wherein pressure source moves from the first configuration to the second configuration and wherein the input of the output conduit communicates with the drug and the output end of the output conduit is receivable in the individual.

Abstract: An electronic injector including an electronic on-body injector for use with a patient to deliver a fluid through an injection device. The electronic on-body injector includes a fluid reservoir; a MEMS pump; a bolus injection needle, the bolus injection needle having a bolus injection needle tip aligned with the injection port, the bolus injection needle being slideably biased away from the injection port to define a gap; and a bolus needle button operably connected to the bolus injection needle to slide the bolus injection needle along the injection axis. The bolus needle button is operable to advance the bolus injection needle tip to close the gap and advance the bolus injection needle tip into the injection port to form a bolus injection flow path. The bolus needle button is further operable to activate the MEMS pump to deliver a predetermined bolus volume.

Abstract: A disposable cassette intended for a metering pump for infusion consisting of just two components, namely, a hollow first component (1) forming a pump body, and a second component (5) collaborating with the hollow first component (1) to form a pumping zone (6) and comprising a flexible part (10) characterized in that the second component (5) further comprises a rigid part (9) secured to the flexible part (10) and able to be assembled with the hollow first component (1). The invention also relates to a method for manufacturing such a disposable cassette.

Abstract: An improved elastomeric pump for an infusion assembly. The pump includes a generally cylindrical mandrel body with first end, an opposed second end, a length, an outer diameter corresponding to a first radius (Rmandrel), a central bore extending through the length, a first port extending from the outer diameter to the bore to provide a fluid passageway, a fill port and an exit port in fluid communication with the bore. The pump includes an inflatable elastomeric tube disposed concentrically about the mandrel, the tube being sealingly secured on the mandrel near the respective ends of the tube and having an original inner diameter that corresponds to a second radius (r) so that it approximately matches the outer diameter of the mandrel (Rmandrel), a length (L) less than the length of the mandrel, a wall thickness (t) such that: (0.4225×r)<t?(0.660×r).

Abstract: Disclosed herein is a microfluidic pumping device having a piezoelectric member positioned above a displaceable membrane. A voltage is applied across the piezoelectric member causing the piezoelectric member to displace the membrane. Displacement of the membrane increases and decreases pressure in a cavity that is below the membrane. The increases and decreases in pressure actuate cantilevered check valve members to facilitate unidirectional liquid flow through the pumping device.

Abstract: The present invention provides a selectively activatable patch-pump assembly, said patch-pump assembly comprising: •a sealed prefilled drug-reservoir containing a drug to be delivered; •an associated conduit in connection therewith; •a selectively activatable penetrator which penetrates said sealed prefilled drug-reservoir and facilitates drug access to said conduit; and •a selectively activatable, associated, cannula-containing assembly for delivering a drug subcutaneously to a subject, in fluid connection with said conduit; wherein a selective activation-step initiates penetration of said sealed prefilled drug-reservoir, drug access from said drug-reservoir to said conduit, drug access from said conduit to said cannula-containing assembly and delivery from said cannula-containing assembly, thereby being a selectively activatable patch-pump assembly.

Abstract: Sensor for dynamically detecting the residual fluid volume Vres of a collapsible reservoir (1,3) characterized by the fact that it is adapted to detect a threshold pressure Pth which corresponds to a phase within said reservoir (1,3) when only said residual fluid volume Vres remains, said residual volume Vres corresponding to a safety volume sufficient to ensure a safety margin to alert the user before the reservoir (1,3) is empty.

Abstract: An implantable infusion pump system is disclosed. The pump system preferably includes an implantable pump and a programmable module. The module may provide for varying flow rates of fluid being dispensed from the pump or may provide for a constant flow rate of such fluid. In the case of varying flow rate capabilities, the module preferably includes one or more sensors to determine information relating to the flow rate, electronics for analyzing the flow rate information, and a mechanism for physically altering the flow rate. In certain embodiments, the module includes a hermetically sealed housing. Methods of dispensing a medicament to a patient utilizing such a system are also disclosed, as are variations of the pump system.

Abstract: Linear peristaltic pump for pumping a fluid through a flexible tube (13) comprises a rotatable central member (34) with a plurality of radially disposed planetary gears (51-53). An offset roller (61-63) is disposed on each of the planetary gears (51-53). The flexible tube (13) is inserted between a generally flat compression surface (40) and at least one of the plurality of rollers (61-63). Rotation of the central member (34) enables the plurality of rollers (61-63) to serially collapse the flexible tube (13) and to move in a substantially linear motion along the generally flat compression surface (40) for pumping the fluid through the flexible tube (13).

Abstract: A drug delivery device for delivery of medicament having a delivery pump system and a cartridge system, the delivery pump system operating electromagnetically by driving two disk magnets that are housed within pump body inserts of the cartridge system. The displacement of the magnets and an elastomer membrane placed between the magnets of the cartridge system results in a volumetric change within two reservoirs and the flow of medicaments. The medicament flows from the reservoirs to the inlet/outlet members via the pump body inserts and discharged to a patient user's body through an infusion set.

Abstract: The present invention relates to a medicament delivery device comprising a housing (12); a medicament container (14) arranged within said housing; medicament delivery drive means (22, 24); manually operable release means (38); and a movement speed control mechanism (44, 46, 48) comprising at least one fixed, flexible and elongated compartment (48) containing a liquid, and at least one flexible speed control member (44, 46) connected to the medicament delivery drive means; wherein said at least speed control member is arranged to be pressing on said at least one compartment for forcing said liquid past said member and thereby creating a movement speed control of said medicament delivery drive means when moved.

Abstract: An improved technique for manufacturing a propellant pillow for use in filling a propellant chamber of an implantable pump is disclosed. The method preferably results in the creation of an already filled propellant pillow, which therefore negates the need for the separate filling of the pillow.

Abstract: In accordance with another embodiment, a controller in a fluid delivery system initiates drawing fluid into a chamber of a diaphragm pump. During a delivery phase of pumping the fluid in the chamber to a target recipient, the controller applies pressure to the chamber. At multiple different times during the delivery phase, the controller temporarily discontinues application of the pressure to the chamber to calculate how much of the fluid in the chamber has been pumped to the target recipient.

Abstract: In various embodiments, a device for delivering pressurized irrigation may include a squeeze plate and a pressure sensor module. The squeeze plate may move relative to the pressure sensor module to apply pressure to a flexible container (e.g., a bag of irrigation fluid) between the squeeze plate and the pressure sensor module. The pressure sensor module may include a pressure sensor to measure a force exerted on the pressure sensor module by the flexible container as pressure is applied to the flexible container from the squeeze plate. In some embodiments, the pressure sensor module may include a bag contact plate and the pressure sensor may measure a force exerted on the bag contact plate by the flexible container located between the bag contact plate and the squeeze plate. In some embodiments, the pressure sensor may sense a pressure associated with the flexible container without an intervening bag contact plate.

Abstract: An infusion system and method for controlling the fluid flow from a pump includes a pump system that has a controller that utilizes an algorithm to control the flow rate of fluid through tubing. A plurality of electrodes operatively contacts an electrically conductive portion of the tubing that is also acted upon by the pump system. The electrodes monitor electrical properties of the tubing and provide an electric signal indicative thereof to the controller, which varies the flow rate of the fluid through the tubing as a result of the electric signal.

Abstract: Novel fluid delivery systems are disclosed to improve the delivery of bio-compatible fluids to a patient. The systems can include a housing having a bladder pressurized by a pressurization unit so that fluid flow rate can be controlled, changed and/or monitored. The systems can also include a scale and/or a flow control unit.

Abstract: A pumping device is disclosed, as for use with an enteral feeding assembly. In one form the pumping device is a diaphragm pump including a first dome portion, a second dome portion, and a flexible membrane located between the first and second dome portions. A pressure differential is created between the two chambers thus created by membrane, so as to meter fluid (to be delivered) to a patient. The fluid to be delivered may be located in one of the chambers. A portable fluid pump is also provided including a syringe and spring pump drive mechanism mounted in a casing. The spring pump drive mechanism has two piston devices in fluid communication with each other. As one piston device moves in one direction within its associated driving barrel, it serves to drive the other piston device.

Abstract: The present invention involves, in some embodiments apparatus, such as dialysis apparatus, and methods for pumping fluid. Certain embodiments comprise a housing enclosing a pump drive assembly for actuating at least one pump on a removable fluid pumping cassette. The housing may comprise a door connected to the housing for enclosing an installed cassette in the housing upon closure of the door. The pump drive assembly may comprise a mating block configured for operative association with an installed cassette and to may be configured to permit a sealing engagement with an installed cassette upon closure of the door. To facilitate sealing, certain embodiments of the door include a movable compression plate configured to exert a compressive force on an installed cassette against the mating block when the door is in a closed position.

Abstract: A cartridge system for delivery of medicament includes as membrane placed between two disk magnets that are housed within pump body inserts. The pump body inserts having flow channels and fluid openings are between two inlet/outlet members. The inlet/outlet members each having a fluid outlet component and fluid openings are securely engaged to two reservoirs containing fluid medicaments.

Abstract: Embodiments of the present invention provide drug-delivery devices comprising a drug reservoir chamber containing a substance to be delivered, in fluid connection with a drug administration means, and at least one displacement-generating battery cell coupled to said drug reservoir chamber by a coupling means, the at least one displacement-generating battery cell comprising an element that changes shape as a result of discharge of the battery cell so as to cause a displacement within the battery unit, the arrangement being such that the displacement derived from said battery unit is conveyed by said coupling means to cause displacement of at least a portion of a wall of said drug reservoir chamber reducing the volume of said drug reservoir chamber such that said substance is expelled from said drug reservoir chamber towards said drug administration means upon discharge, thereby being a self-powered drug delivery device.

Abstract: A device for dispensing fluid to a patient enabling either or both of a continuous flow, as well as successive, large-volume boluses. A first reservoir provides a source of fluid under pressure. A bolus flow path provides for the delivery of a bolus dose of fluid and an optional continuous flow path provides a continuous flow rate of fluid. Both flow paths are in fluid communication with the source of fluid. A bolus delivery system in fluid communication with the bolus flow path receives fluid from the first reservoir, expands to pressurize fluid, stores the pressurized fluid, and dispenses the pressurized fluid while avoiding bolus refill until enabled to expand in a subsequent delivery cycle. An actuator releases fluid from the bolus delivery system such that when actuated by the patient, fluid is permitted to flow out of the bolus reservoir to the patient without further action by the patient.

Abstract: An infusion device having a housing with a reusable control portion and an expendable reservoir portion includes a precise drive for an infusion pump. The drive includes a piezoelectric bender assembly, a limiter and at least one contact stop. The piezoelectric bender assembly includes a cantilevered piezoelectric bender having an member of predetermined thickness fixed to move with the second end. A limiter of dimensionally stable material including a gap and at least a first mounting hole extending to the gap. The member of predetermined thickness extends into the gap. A first contact stop is positioned in the gap to define a critical gap distance limiting movement of the member of predetermined thickness in the gap. A base has a mounting surface, a port through the base and extending to the mounting surface. The port includes a first length having a smaller diameter at the mounting surface and a second length displaced from the mounting surface and having a larger diameter.

Abstract: A reservoir for use in a wearable infusion device includes a substantially rigid base having a perimeter, a substantially rigid top having a perimeter, and a flexible rolling diaphragm between the base and the top. The diaphragm has an outer perimeter sealed along the perimeter of the base and an inner perimeter sealed along the perimeter of the top. The diaphragm is arranged to dispose the top and the base immediately adjacent each other when the reservoir is empty and to dispose the top and the base in spaced apart relation when the reservoir is full.

Abstract: A micropump, which in particular is a pump for a medicinal active substance and which may be an insulin pump or an analgesic pump, has at least one valve, which has a valve chamber, and has a pump chamber. At least one immobile structural element, which reduces the valve chamber volume, is provided in the valve chamber.

Abstract: Methods, systems, and apparatuses for delivering therapeutic fluid to a user are disclosed. The apparatus includes a pump mechanism for pumping therapeutic fluid to the user having a reusable part which includes a housing and a disposable part configured to be inserted into the housing of the reusable part and to be connected with the reusable part. The connection of the reusable part and the disposable part enables operation of the pump mechanism and disconnection of the reusable part and the disposable part disables operation of the pump mechanism.

Abstract: The invention provides a finger-type peristaltic pump (2) having a body (4) and a housing (6). The body contains two or more finger-type valves (16) and a processor (22) configured to operate the valves according to a predetermined temporo-spatial pattern. The housing has a passageway (18) configured to receive a conduit. The housing has a first position in which a conduit in the passageway is positioned adjacent to the valve fingers, and a second position in which a conduit in the passageway is not adjacent to the valve fingers. The invention also provides a housing for use in the pump of the invention.

Abstract: A roller pump conduit defining a pump chamber is provided. The roller pump conduit includes a roller contact portion having a fill region and a delivery region. The fill region has a first taper configured to determine volume delivery per revolution of a roller head. The delivery region has a pressure region having a second taper and a discharge region having a third taper. The third taper has a lesser degree of taper than the second taper. The delivery region is configured to produce a pulsatile flow out of the conduit. Furthermore, a roller pump having a roller pump conduit is provided. The roller pump conduit of the roller pump has a fill region and a delivery region, the fill region having a first taper, and the delivery region having a second and third taper, wherein the third taper has lesser degree of taper than the second taper.

Abstract: An infusion pump comprises at least three operating layers. A first layer includes epicyclic gear means comprising a rotatable central gear, a stationary outer ring gear, and movable planet gears arranged between the central gear and the ring gear in movable engagement with the central and ring gears. A second layer includes roller bearing means comprising a stationary outer ring and a movable inner roller arrangement in movable arrangement with the outer ring and coupled with the epicyclic gear means to provide a rotational bearing for the central and planet gears. A third layer includes rotary peristaltic pump means comprising stationary flexible tubing which includes a bent portion having an essentially part-cycle form and a rotor having engagement elements to squeeze the bent portion during rotation for a pump action, wherein the rotor is coupled with the central gear to transfer torque from the central gear to the rotor.

Abstract: Medicament devices include a sealed medicament dose container comprising a cell based medicament that is stored at a temperature less than about ?40 degrees Celsius, then thawed into a liquid prior to administration and a medicament dose cartridge configured and sized to snugly hold the dose container therein during extraction of the liquid medicament. Related dose containers, retainers and extraction/dispensing systems are also described.

Abstract: An external infusion device that infuses a fluid into an individual's body includes a housing, a reservoir, a drive system, a power supply, electrical elements, and a tab. The reservoir contains the fluid, and the drive system forces the fluid from the reservoir. The electrical elements control the power to the drive system to regulate the rate that fluid is forced from the reservoir. The tab mates with the housing, and contains at least one electrical element. The tab is removable, and may be replaced with a different tab. The different tab may change the rate fluid is forced from the reservoir. A tab may be removed from one external infusion device and installed in a different external infusion device. The tab may be limited to use in a predetermined number of external infusion devices and may include a power supply.

Abstract: An environmentally sensitive hydrogel material swells or collapses in response to a parameter such as pH level associated with consumption of food by a patient. This swelling or collapsing is harnessed to treat morbid obesity or some other condition of the patient. The swelling or collapsing of the hydrogel may be used to tighten a gastric band or gastric valve when the patient starts eating; then loosen the band or valve when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to increase the size of a space occupying device in the patient's stomach when the patient starts eating; then decrease the size of the space occupying device when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to selectively restrict the absorption of nutrients within a patient's gastrointestinal tract, such as in the duodenum.

Abstract: A variable hydraulic resistor for use with implantable pumps is disclosed. The variable hydraulic resistor according to the present invention is particularly useful in varying the flow rate of a medication fluid from an otherwise constant flow implantable pump. An implantable pump is also disclosed, which does not require a complicated clinching system or the like, and which may include an undulating membrane and chamber design to reduce the height of the pump.

Abstract: A tubular pumping element for pumping a liquid is disclosed. The tubular pumping element includes an outer shell that has a bore with an inlet and an outlet at opposite ends of the bore. There is a flow path for the liquid from the inlet through the bore to the outlet. A support element is located within the bore of the outer shell. An elastic sleeve is located over the support element and has a plurality of expandable portions. The support element includes a plurality of fluid passages each coupled to a respective port on the surface of the support element under one of the plurality of expandable portions of the elastic sleeve. Introduction of a driving fluid into one of the fluid passages causes the expandable portion of the elastic sleeve that is proximate to the respective port to expand.

Abstract: The invention concerns a system and a method of use of said system for performing fluid administration on a patient, the system comprising a liquid pump, a liquid distribution system, a liquid supply means, and patient conduit. The liquid distribution system comprises two distinct hub chambers. The first hub chamber includes at least one liquid supply port with a dedicated valve means, one patient port with dedicated valve means, and one pump inlet. The second hub chamber includes at least one patient port or warmer port with dedicated valve means and one pump outlet. The system further comprises control means arranged to close the patient port of the first hub chamber when the liquid supply port is open, and vice versa.

Abstract: A wearable infusion pump assembly includes a reservoir for receiving an infusible fluid, and an external infusion set configured to deliver the infusible fluid to a user. A fluid delivery system is configured to deliver the infusible fluid from the reservoir to the external infusion set. The fluid delivery system includes a volume sensor assembly, and a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the volume sensor assembly. The volume sensor assembly is configured to determine the volume of at least a portion of the quantity of fluid. The fluid delivery system further includes at least one optical sensor assembly configured to sense the movement of the pump assembly, a first valve assembly configured to selectively isolate the pump assembly from the reservoir, and a second valve assembly configured to selectively isolate the volume sensor assembly from the external infusion set.

Abstract: A pinch clamp assembly for engaging a tube with an enteral feeding or infusion pump adapted to feed nutritionals or to infuse medical solutions to a patient, is provided comprising a base (1) comprising holding means (3) for holding a pumping section (10) of the tube in operative engagement with the base (1) and supporting means (5) for supporting a connector (6), a clamping element (7) having clamping surfaces engageable with the pumping section (10) and moveable between an open position allowing flow of fluid through the pumping section (10) and a closed position wherein the pumping section (10) is occluded by the clamping element (7), and locking means adapted to engage with each other in the closed position and adapted to interact with releasing means external to the pinch clamp assembly so as to bring the clamping element (7) from the closed to the open position, a connector (6) for connecting the tube with a port on a patient, the connector (6) being removable from the pinch clamp assembly, the clamping