Abstract: A system for bone cement includes a vial holder configured for receiving a vial and including a holding structure for maintaining the vial in the vial holder. The vial includes a monomer component for bone cement. A holder chamber is configured to receive and secure the vial holder. The vial holder is advanced toward a vial-breaking device for breaking the vial and releasing its contents into the holder chamber past the elastomeric seal. Once the vial holder is advanced further the elastomeric seal is deformed to form a seal and prevent fumes produced from escaping from the device.

Abstract: The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support comprises a projecting portion, which projects from the syringe support in a distal direction and a flexible portion which axially adjoins the projecting portion. The flexible portion is adapted to axially bias the syringe in the distal direction within the housing. The disclosure further relates to an autoinjector.

Abstract: An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier may include two identical parts that are discrete from one another and interlock with one another. Carrier includes a cushion to support the syringe. Protrusions may be provided on cushion to further support syringe. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Abstract: A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member. The plunger member includes a rotatable member configured to insert the stopper member distally in the syringe interior relative to the syringe body with rotation of the rotatable member. The plunger member further includes a proximal portion proximal of the rotatable member configured to be moved distally to also insert the stopper member distally in the syringe interior relative to the syringe body to eject about microliters of fluid from the syringe interior.

Abstract: An autoinjector for dispensing a liquid product includes a housing; a product container arranged in the housing, particularly, a syringe comprising a displaceable piston; a drive member; a first spring which acts on the drive member and the piston to dispense the product from the container; signal element releasably axially coupled with the drive member so that the signal element is transported in the dispensing direction as the drive member is displaced; and a second spring, which exerts a spring force on the signal element against the dispensing direction and is tensioned as the signal element is transported in the dispensing direction. When the signal element is released or detached from the axial coupling, the second spring causes the signal element to accelerate opposite the dispensing direction and strike against a signal stop and generate an acoustic and/or tactile signal.

Abstract: A plastic flange for a medical container, the plastic flange defining an opening, the opening being surrounded by a peripheral collar, the collar providing a support to a user's fingers, wherein the flange comprises connecting means for connecting the flange to an external surface of a tubular barrel of the medical container, and wherein the flange further comprises a remotely readable electronic component for remote identification of the medical container, the remotely readable electronic component being embedded into the plastic flange.

Abstract: A system for bone cement includes a vial holder configured for receiving a vial and including a holding structure for maintaining the vial in the vial holder. The vial includes a monomer component for bone cement. A holder chamber is configured to receive and secure the vial holder. The vial holder is advanced toward a vial-breaking device for breaking the vial and releasing its contents into the holder chamber past the elastomeric seal. Once the vial holder is advanced further the elastomeric seal is deformed to form a seal and prevent fumes produced from escaping from the device.

Abstract: A pump device includes a rotary motor, a compartment for insertion of a disposable pump part, and one or more pulsation-reduction elements. The disposable pump part includes an input port, an output port, and a dual-action reciprocating assembly. The input port is configured for intaking fluid. The output port is configured for outputting the fluid. The dual-action reciprocating assembly is configured for pumping the fluid. The assembly includes a single piston and a rod configured to be coupled to the rotary motor, so as to drive the piston. The one or more pulsation-reduction elements are configured to reduce a pulsation in the outputted fluid, caused by the single-piston dual-action reciprocating assembly.

Abstract: The present invention provides a medical device containing a cake composition comprising aripiprazole as an active ingredient and capable of suppressing agglomeration of aripiprazole in a suspension obtained by resuspending a freeze-dried substance; and a cake composition comprising aripiprazole as an active ingredient. The present invention relates to a medical device containing, in a storage container whose inner wall is treated with silicone, a freeze-dried cake composition comprising separately prepared aripiprazole as an active ingredient, wherein there is a space between the inner wall and the cake composition; and a cake composition comprising aripiprazole as an active ingredient and having a strength of 5 to 100 N.

Abstract: A controlled delivery syringe device includes a syringe barrel having a proximal end and distal end which defines a chamber for containing an injectable material. A plunger rod is associated with the syringe barrel and a plunger is secured thereto which is axially movable within the syringe barrel. A plurality of equally and sequentially spaced periodic features are associated with the plunger rod and a counter member is engageable with the periodic features. Application of a distally directed force to the plunger rod results in disengagement and reengagement of the counter member with the sequentially spaced periodic features on the plunger rod, enabling advancement of the plunger rod and plunger in the syringe barrel while providing tactile feedback of dose progression of the injectable material. A method of retrofitting a syringe with a device for injecting a metered dose of injectable material is also provided.

Abstract: A fat suction and graft syringe includes a negative pressure adjustment mechanism. The negative pressure state in a barrel can be maintained during a procedure only by pulling and releasing a plunger, and only by slightly rotating the plunger. The plunger can be pushed inside the barrel without being constrained by a multi-level holding plate and a single-surface rotation clip, whereby the syringe has enhanced convenience in the use and production thereof so that many practitioners accustomed to using a normal syringe can easily use the syringe without separately learning how to manipulate the syringe.

Abstract: The present disclosure relates to systems and methods for mixing and injecting fluid treatment, such as cement to treat bone or hard tissue. In some embodiments, a mixing apparatus may facilitate mixing within a syringe. Additionally, the syringe may be configured to extract bone cement from a cement mixer. A syringe for mixing and injecting cement may include a detachable handle that may be detached after extracting bone cement from a mixer to facilitate coupling to a high-pressure syringe for injection.

Abstract: The invention provides a syringe for use in an ophthalmic injection. The syringe comprises a body, a stopper and a plunger. The body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet. The plunger comprises a plunger contact surface at a first end and a rod extends between the plunger contact surface and a rear portion. The plunger contact surface is arranged to contact the stopper but not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, reducing the volume of the variable volume chamber, but not to move the stopper away from the outlet end.

Abstract: A piston assembly including a piston for a cartridge discharging device for discharging a pasty compound out of a cartridge which has an inner wall, having a piston and a rear face which can be acted upon by a pressure plate secured to a push rod, a front face opposite the rear face, and a retaining element which secures the pressure plate against the rear face by a retaining protrusion which covers an edge of the pressure plate in a retaining position. The retaining protrusion is secured to the piston in a movable manner into a release position in a direction away from the push rod.

Abstract: The invention relates to an arrangement for detecting a position of a plunger (4) relative to a bung (3) in a drug cartridge (1), comprising a proximity sensor (5) located close to a distal end (6) of the plunger (4) facing the bung (3) and aligned to receive light reflected by the bung (3).

Abstract: A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member. The plunger member includes a rotatable member configured to insert the stopper member distally in the syringe interior relative to the syringe body with rotation of the rotatable member. The plunger member further includes a proximal portion proximal of the rotatable member configured to be moved distally to also insert the stopper member distally in the syringe interior relative to the syringe body to eject about microliters of fluid from the syringe interior.

Abstract: The present disclosure provides a metered dosing assembly configured to dispense a volume of fluid into a container that is selectively sealed by a closure valve having a closure valve member that is movable between sealed and unsealed positions with respect to the container. The metered dosing assembly includes a housing having an interior cavity. A valve is locatable at an end of the housing. The valve includes a valve member, a pin extending from the valve member, and at least one spring leg attachable to the valve member. The pin extends from the valve member and is configured to engage the closure valve member of the closure valve to move the closure valve member to the unsealed position and move the valve member to an open position with respect to the housing. When the valve member is moved to the open position and the closure valve member is moved to the unsealed position, fluid communication is made between the metered dosing assembly and the container.

Abstract: The invention discloses a device for filling an electric cigarette, more specifically for filling a consumable-material tank of an electric cigarette wherein the device has a first tank for accommodating a consumable material and a second tank for accommodating air, wherein the device is designed such that the volumes of the tanks can be altered inversely by means of an actuating device, and therefore a pressing action and an intake action can be established at connections of the tanks. By virtue of the device being connected to a consumable-material tank of an electric cigarette, it is thus possible, while the consumable-material tank is being filled with consumable material, for the air displaced by the consumable material to be simultaneously extracted from the electric cigarette.

Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and assembling them into syringes, e.g., pre-filled syringes.

Abstract: The present invention relates to a drive mechanism for use with a medicament delivery device, comprising a plunger rod (68), a drive spring (72) operably arranged to the plunger rod, an actuator (52) comprising a holding member (60) releasably engaged to the plunger rod (68) for holding said plunger rod (68) with said drive spring (72) in a tensioned state, a rotator (38) operably connected and movable relative to said actuator (52) and configured to interact with said holding member for holding said holding member in engagement with the plunger rod, an activator (30) operably connected to said rotator (38). The invention is characterized in that the activator (30) is configured to rotate and subsequently linearly displace the rotator (38) in relation to the actuator (52) such that said holding member (60) is released from the plunger rod (68).

Abstract: A system comprising a drug delivery device and a cartridge provided with a bung and and a method of identifying the cartridge The present invention relates to a bung (20), to a drug containing cartridge (10) and to a drug delivery device, wherein the bung (20) comprises a coding feature (28) for carrying information regarding at least one of the cartridge (10) and the content of the cartridge (10). Furthermore, it relates to a method for identifying a cartridge (10) containing a medicinal product.

Abstract: Apparatus for attaching a suture to an object, the apparatus comprising: an anchor comprising a body having a distal end and a proximal end, and a vertical bore extending through the body substantially perpendicular to the longitudinal axis of the body; wherein the anchor further comprises a recess formed on one side of the body and a U-shaped slot formed on the opposing side of the body, whereby to form a flexible finger extending distally within the body, and further wherein the distal end of the finger is spaced from an opposing portion of the body; and wherein at least one of the flexible finger and the body comprises a cutout extending therethrough, with the cutout cooperating with the U-shaped slot and the recess so as to together form a suture loading hole extending through the body, with the suture loading hole being sized to receive a suture therein.

Abstract: A drug delivery device, in the form of an injector, may include one of a number of systems for limiting the delivery of a medical fluid or drug product in case of movement of (e.g., removal of) the injector relative to the patient as determined by a proximity sensor. The drug delivery system may in the alternative or in addition include systems for indicating the amount of medical fluid or drug product delivered (or not delivered) in case of movement of (e.g., removal of) the injector relative to the patient as determined by the proximity sensor. The injector may be, for example, an on-body injector or an hand-held autoinjector.

Abstract: A convertible plunger is provided comprising an internal portion and a generally cylindrical exterior surface. At least a portion of the exterior surface is maintained in an initial expanded state by a property of the internal portion. The expanded state is reducible to a constricted state by an operation that is applied to the internal portion of the plunger to alter the property. A film coating may also be applied to a sidewall of the sleeve to reduce a sliding friction between the sleeve and barrel. A film coating may also be applied to a nose cone of the plunger to provide a barrier between the plunger and product in the barrel.

Abstract: In the present invention, a dripless syringe is provided that includes a barrel having fluid therein, the barrel defining an open end and a nozzle opposite the open end, a plunger disposed at least partially within the open end and including a body and a push pin extending from one end of the body, a seal plate slidably mounted to the push pin and a bung disposed over the seal plate and the push pin and sealingly engaged between the seal plate and the barrel the seal plate enables the bung to remain in sealing engagement with the interior of the barrel while the plunger is moved within the barrel. Further, when pressure is removed to cease dispensing of the fluid, the pin allows the bung to retract and provide a negative pressure on the fluid to prevent drips of fluid from leaking out of the nozzle.

Abstract: The invention relates to a driving device for an injection device for administration of a liquid drug. The driving device has inter alia a rotary member, rotation of which relative to the housing causes a pretensioned spring to move a propulsion member in the dispensing direction, and a coupling which is closed and is opened by pressing of an actuating member, the opened coupling enabling the rotation of the rotary member in a first direction of rotation, and the actuating member being coupled to the rotary member such that pressing of the actuating member causes the rotary member to rotate already when the coupling is still closed.

Abstract: A limiter for a dispensing device is provided. The limiter includes a body (20) arranged to mount with at least a portion of a dispensing device (300), and a stop extending from the body. The stop (40) is configured to permit movement a plunger of the dispensing device a predetermined distance in a dispensing direction correlated to a desired volume of medium to be delivered from the dispensing device. The stop is configured to prevent further movement of the plunger in the dispensing direction, thereby limiting the amount of medium delivered from the dispensing device. The dispensing device may be a syringe.

Abstract: A syringe having a finger flange and a finger support is provided. The finger flange includes a radially projecting support surface for a finger and is joined to the syringe body of the syringe at its proximal end. In this case, the finger flange is further designed in one piece and includes at least two finger flange elements, which are movably joined with one another.

Abstract: Sample processing methods and systems to collect a biological sample. A device may be configured collect a predetermined volume of a sample in sample chamber, and seal the chamber upon activation. The device may be further configured to mix the mix the sample with a predetermined volume of a reagent and/or mix the sample and the reagent in a pre-determined ration.

Abstract: The invention refers to a dispensing speed control mechanism for use in an injection device having a release button, which is displaceable to initiate dispensing of a set dose, a first component part, which is driven by a power reservoir during dose dispensing, and a second component part, which is stationary during dose dispensing. The speed control mechanism includes friction means for retarding the first component part during dose dispensing depending on the position of the release button. Further, the invention refers to a handheld injection device with such a speed control mechanism.

Abstract: A tri-ring syringe which includes a barrel (1) having a distal end and a proximal end. The proximal end of the barrel (1) is provided with a double ring handle. The syringe also includes a plunger (2) including a distal end and a proximal end, the proximal end of the plunger (2) being provided with a single ring handle (5), the distal end of the plunger (2) connecting with a rubber stopper (6) and being inserted into the interior of the barrel (1); and an insertion part (3) connected to the barrel (1) and rotating synchronously with the barrel. The invention allows the torque of the rotation of the barrel (1) to be transmitted outward.

Abstract: A fluid collection assembly (10) and method for use thereof is provided including a fluid collection cartridge (20) having a tubular member (21) with a plunger assembly slidably inserted. The plunger assembly includes a stopper (32) and a plunger rod (31). The stopper and plunger rod are removably interlocked together which enables the plunger rod to exert a force in a distal direction on the stopper and to be removed from the stopper upon the application of a proximal force thereto. The fluid collection assembly is particular useful in the collection of arterial blood. In use, the assembly is primed with a liquid anticoagulant, the plunger rod is removed, and a blood sample is collected with the arterial pressure causing the stopper to travel in a proximal direction along the cartridge.

Abstract: The embodiments disclosed herein relate to lockable syringe assemblies and related devices and methods. The syringe assembly may include a barrel, a plunger, and a locking mechanism. In some arrangements, the locking mechanism is an elastomeric locking ring or a rigid partial ring. The plunger may include a plurality of ribs and is longitudinally moveable within the barrel. Once the plunger is disposed at a desired longitudinal location, the plunger can be axially rotated and locked in such a way that further longitudinal movement is restricted.

Abstract: A controlled pressure inflation-deflation device inflates a balloon to occlude a blood vessel by moving a large plunger to provide incremental pressure increases within a syringe. A releasable latch moves a second plunger, positioned within a syringe formed by an inner columnar opening in the large plunger, between an occlusion position and a perfusion position. A three-position switch has a release position to allow the large plunger to move freely, an adjust position to provide the incremental pressure increases, and a lock position to lock the location of the plunger. Pressures at which various balloons (e.g., folded balloons) achieve or nearly achieve a substantially circular cross-section may be extrapolated by inflating balloons with pressures equal and/or greater than the first occlusion pressure. Balloons may be pre-inflated up to or below the first occlusion pressure to achieve a substantially circular cross-section, prior to increasing the balloon to an occlusion pressure.

Abstract: A medical syringe, having a syringe barrel, a piston, a plunger rod, and a plunger rod holder, wherein a barrel main body of the syringe barrel is formed to have a small inner diameter part and a large inner diameter part, the piston is formed such that the circular part is comprised of an elastic material and has an outer diameter larger than the inner diameter of the small inner diameter part of the barrel main body so that the outer periphery of the circular part can be brought into contact with the inner peripheral surface of the small inner diameter part by pressurizing, and the piston can be held in the large inner diameter part of the barrel main body in a state of being freely fitted thereto.

Abstract: An auto-injector comprises a chassis to contain a syringe with a, needle and a stopper, a needle shroud slideable within the chassis and adapted to rest on the skin of a patient, a plunger adapted to translate the stopper to expel medicament, a coupling shroud slideable within the chassis and releasably coupled to the plunger and a drive means, the drive means driving the coupling shroud proximally from a first position Proximal movement of the coupling shroud translates the syringe exposing the needle, depresses the plunger to expel medicament and advances the needle shroud to a safe position to surround the needle. The needle shroud arranged to prevent decoupling of plunger and coupling shroud when the needle shroud is in a retracted position, whereas the needle shroud is arranged to allow decoupling of plunger and coupling shroud when the needle shroud is moved towards the safe position.

Abstract: A biopsy system with a grid plate used as either a lateral or medial compression plate of a localization fixture used with a breast coil includes a rotatable guide cube that may be inserted into a desired rectangular recess in the grid plate after rotating to position a selected guide hole in the desired spatial orientation. Versions of a guide cube include those rotatable in two axes to provide additional hole positions, angled holes, enlarged circular holes that function with a rotating guide to support a noncircular biopsy instrument cannula (e.g., trocar/sleeve combination, core biopsy probe of a biopsy device) for rotation. A rotating guide may have an unlocked state for easily sliding to a selected longitudinal position thereon. Thereafter, the rotating guide is locked to serve as a positive depth stop (e.g., quarter turn locking elastomeric rings, triangular and scissor clips, and shutter depth stops).

Abstract: The present invention relates to a finger-grip device designed to be placed on the flange of a cylindrical barrel of a medical syringe or cartridge, increasing the contact surface with the fingers of the operator during the injection or withdrawal of fluids to or from a patient, characterised in that it does not stop or hinder the run of the plunger within the cylindrical barrel.

Abstract: A new syringe design is provided with a safety feature that prevents inadvertent or otherwise unintended release of any contents within the syringe. This safety feature is accomplished by way of an automatic (passive) plunger locking mechanism. The new syringe design also providing for automatic (passive) disengagement of the automatic plunger locking mechanism so as to not inhibit the operating use and function of a syringe.

Abstract: A syringe-assist device including a housing portion, an actuator portion, and a syringe-supporting member. The housing portion includes body defining an axial passage. The actuator portion is connected to and is partially disposed within the axial passage of the body. The syringe-supporting member is movably-disposed within the axial passage. The syringe-supporting member fluidly separates the axial passage into a first, proximal passage portion and a second, distal passage portion. The actuator portion is movably-disposed within the second, distal passage portion of the axial passage. The syringe-supporting member defines a fluid-flow passage that fluidly-connects the first, proximal passage portion of the axial passage to the second, distal passage portion of the axial passage. A method is also disclosed.

Abstract: An apparatus comprises a plunger able to fit in a cartridge or syringe. The plunger includes an outer portion and a deflection portion. The outer portion is able to engage the body of the cartridge or syringe. The outer portion is operable to apply a first radial force to the cartridge or syringe. The deflection portion is positioned within the outer portion and is movable between a locked position and an unlocked position. The deflection portion in the unlocked position causes the outer portion to apply a second radial force to the cartridge or syringe.

Abstract: The invention relates to a transmission arrangement for controlling a force of a translation, the transmission arrangement comprising a drive collar (13) connectable to a translative drive means (11) and prevented from rotating with respect to a ground (12) of the drive means (11), a flange face of the drive collar (13) bearing against a mating flange face of a friction collar (20), the friction collar (20) slidable in longitudinal direction and rotationally constrained by engagement in a cam track (12.3), another flange face of the friction collar (20) bearing against a mating flange face of a plunger (8), the plunger (8) slidable in longitudinal direction and prevented from rotating.

Abstract: An injection device including a barrel, a hollow plunger having a portion structured and arranged to move within the barrel, a needle unit, and a safety system that one of automatically causes the needle unit to retract into the plunger when the plunger reaches a substantially fully depressed position and utilizes a frangible or breakable seal arranged within the plunger. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

Abstract: A medicated module comprising a connecting body configured for attachment to a drug delivery device. A first needle is fixed within the connecting body and an outer body operatively coupled to the connecting body. A needle guard operatively coupled to the outer body and a biasing member positioned between the outer body and needle guard. A second needle fixed within the outer body and a recess within the connecting body defines a reservoir. The reservoir contains at least one dose of a medicament and is configured for fluid communication with the first and second needle.

Abstract: An intradermal injection device comprises a housing, a foot with an opening for passage of a needle; a reservoir movably mounted in the housing, and having a hollow space for holding a fluid; a hollow needle movably mounted in the housing and having a first end for penetrating the subject's skin and a second end for penetrating the reservoir, a plunger movably mounted in the housing for moving the needle through the opening for penetrating the subject's skin, and for pressing the fluid out of the reservoir. The reservoir is frictionally mounted inside the housing by first friction means, and the plunger is frictionally mounted to the reservoir by second friction means. The force to overcome the second friction is larger than the force to overcome the first friction.

Abstract: The syringe includes first and second outer cylinders having a flowing port at a distal end through which liquid is flowable, and a plunger inserted from the proximal side of the outer cylinder. The syringe includes a tooth portion provided along the direction of movement of the plunger, and a hook configured to lock the tooth portion at a predetermined locking position and prevent the movement of the plunger in the direction toward the proximal end. The hook retracts from the locking position in association with the unlocking operation and restores automatically to the locking position after the unlocking operation.

Abstract: A resettable drive mechanism for a medication delivery device comprising a housing and a drive member rotatable in a second direction for delivering a dose. A piston rod driven distally when a drive member rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery and reset position. When the clutch member is in the delivery position, the stop member and the drive member engage and the drive member is prevented from rotating in the first direction. When the clutch member is in the reset position, the drive member and the stop member disengage. The drive member is rotatable in the first direction.

Abstract: A syringe is disclosed.

Abstract: Provided are a syringe and a mounting fixture by which it can be facilitated to perform delivery of a target amount of a liquid selectively only when necessary. A syringe is provided with: an external cylinder which is fillable with a liquid; a plunger which is translatable within the external cylinder along the longitudinal direction of the external cylinder and which is formed with a plurality of concave portions and convex portions aligned in the longitudinal direction; and an annular mounting fixture which is mountable to the external cylinder. The mounting fixture is provided with: protruding portions which contact at least the convex portions sequentially in a slidable manner as the plunger is translated; and a rotation limiting member which contacts the plunger to limit a rotation of the plunger relative to the external cylinder.

Abstract: Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration.