Means For Preventing Accidental Displacement Of Piston Patents (Class 604/220)
  • Publication number: 20140180218
    Abstract: A refill module for use with a plunger assembly and having a housing (30), a syringe subassembly (70), a carrier (120) and at least one latching element (170). The syringe subassembly is shiftable within the housing from a retracted position to an injecting position at which its injection tip projects beyond the housing end. The carrier has a passageway in which a plunger of a plunger assembly is insertable for advancement of a piston (80) of the syringe subassembly. The syringe subassembly is engagable by the carrier to be moved from its injecting position to a point at which the injection tip is retracted within the housing when the carrier shifts from a first axial position to a second axial position. The at least one latching element is shiftable relative to the carrier from a retracted arrangement to a latching arrangement such that a latch surface of the latching element restricts a size of the passageway to prevent plunger withdrawal.
    Type: Application
    Filed: August 21, 2012
    Publication date: June 26, 2014
    Applicant: ELI LILLY AND COMPANY
    Inventors: Jesse Arnold Fourt, Jennifer Ellen Davis-Wilson, James R. Yurchenco
  • Patent number: 8740855
    Abstract: A braking mechanism for a retractable safety syringe is disclosed herein. In a first embodiment, the braking mechanism is disposed about the distal end of a piston. The braking mechanism may comprise a friction material about a post attached to a piston. The friction material is displaced from a seat to a landing when the piston is traversed to a fully extended position to disengage the braking mechanism. In a second embodiment, the braking mechanism is disposed at a proximal end of a syringe body. The braking mechanism has a friction member which engages an outer surface of a rigid shaft of a plunger. The friction member is selectively pivotable to disengage the braking mechanism.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: June 3, 2014
    Assignee: Credence Medsystems, Inc.
    Inventor: Richard B. Oliver
  • Patent number: 8740854
    Abstract: A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: June 3, 2014
    Assignee: Becton, Dickinson and Company
    Inventors: Eric Schiller, Michael V. Quinn, Johanna Torres, E Guan, Anthony Economou, Gang Ju
  • Publication number: 20140142516
    Abstract: A drive mechanism of a drug delivery device is presented comprising of a piston rod extending in an axial direction to be operably engaged with a piston of a cartridge, the piston rod being adapted to exert distally directed pressure to the piston for expelling a liquid medicament from the cartridge. A housing component to accommodates the piston rod and has a guiding member extending in a lateral plane and being engaged with piston rod for guiding the same in axial direction relative to the housing component. At least one actuation lock is used to engage with the piston rod to inhibit a proximally directed movement of the piston rod relative to the housing component.
    Type: Application
    Filed: July 12, 2012
    Publication date: May 22, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Michael Jugl, Gunther Sendatzki
  • Publication number: 20140128841
    Abstract: Medical devices are described herein. More particularly, the disclosure relates to controlled injection devices, systems, and methods used for the introduction of treatment material into a cavity. An exemplary controlled injection system comprises an injection device and a jig. The jig is adapted to receive the injection device and has a jig head, jig shaft, and a jig housing.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 8, 2014
    Applicant: Cook Medical Technologies LLC
    Inventors: Darin Schaeffer, Daniel Dalenberg
  • Publication number: 20140094769
    Abstract: The present invention relates to medical devices and particularly to a medication delivery device for self-injection of a medication, or for healthcare professionals to administer a medication. In one embodiment, a medication delivery device utilizes a source of gas pressure to deploy a needle, deliver a desired amount of medication through the needle, and retract the needle for disposal. Fluid flow paths from the source of gas pressure communicate the gas pressure to the needle and to the medication in order to accomplish these steps. In one embodiment, a valve is positioned to open and close the flow of the pressurized gas to the needle and the flow of the medication to the needle, so that the valve can be operated to deploy the needle and deliver the medication through the needle when the user is ready for the injection. The valve can also be operated to retract the needle when the dose is complete.
    Type: Application
    Filed: September 23, 2013
    Publication date: April 3, 2014
    Inventors: CHORNG-FURE ROBIN HWANG, David Moore, John Zeis
  • Publication number: 20140074042
    Abstract: A drive assembly for a drug delivery device is disclosed. The drive assembly is connectable with a cartridge holder and comprises a housing, a piston rod, the piston rod being movable in a distal direction for drug delivery, and a guide nut, the guide nut being rotatable relative to the housing around an axis of the assembly and provided for guiding the piston rod. A locking means is provided which is enabled to take an engaged state in which the locking means is engaged with the guide nut in order to prevent rotation of the guide nut and to take a disengaged state in which the locking means is disengaged from the guide nut in order to allow rotation of the guide nut. Moreover, a coupling means is provided, the coupling means being rotatable relative to the housing around the axis of the assembly for interaction with the locking means in order to change between the engaged state and the disengaged state of the locking means.
    Type: Application
    Filed: May 4, 2012
    Publication date: March 13, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Christiane Schneider, Tobias Stever, Michael Harms, Ulrik Jakobi, Ngoo-Jane Lam, Torsten Kraft
  • Patent number: 8636704
    Abstract: Exemplary embodiments provide a syringe plunger formed of a polymeric material. The syringe plunger includes a pressurizer disposed at a proximal end, and a distal end bifurcated into a first plunger arm having a first conical surface and a second conical surface, and a second plunger arm having a first conical surface and a second conical surface. The distal end includes a first contact surface defined by the first conical surface of the first plunger arm and the first conical surface of the second plunger arm, the first contact surface configured to initially contact a firing engagement mechanism, the first contact surface disposed at a first angle of between about 40° and about 80° relative to a longitudinal axis of the syringe plunger.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: January 28, 2014
    Assignee: AbbVie Biotechnology Ltd
    Inventors: Sherwin S. Shang, Esra Ozdaryal, Marc M. Plew, William P. Szechinski
  • Patent number: 8622974
    Abstract: A plunger-driven delivery device for use with a feeding tube for delivering an ingestible material to a user is provided. The delivery device includes a device body having a first chamber, a second chamber and an exit orifice through which the ingestible material is delivered to the feeding tube. A first plunger is disposed in the first chamber, and a second plunger is disposed in the second chamber. The delivery device can be provided with the ingestible material disposed in the first chamber and a flushing liquid disposed in the second chamber. The delivery device is operable to provide sequential delivery first of the ingestible material and then the flushing liquid into the feeding tube. In some embodiments, a mechanical interlock is disposed between the first and second plungers to prevent use of the second plunger until the first plunger has been depressed.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: January 7, 2014
    Assignee: Mead Johnson Nutrition Company
    Inventors: John D. Alvey, Marc S. Velmer
  • Patent number: 8622956
    Abstract: An injection device including a volume for accommodating a product for administration, a piston for acting upon the product within the volume, and a stopper which can be arranged between an end of the piston facing the product and the product within the volume, wherein the piston includes a piston head configured to be sealed in a gas-tight manner, the piston head being separate from the stopper such that a negative pressure or vacuum region can be developed between the piston head and the stopper.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: January 7, 2014
    Assignee: Roche Diagnostics International AG
    Inventor: Ivan Heutschi
  • Publication number: 20130345644
    Abstract: A locking hinge assembly for an injector is disclosed. The injector includes a forward handle member, a rear handle member and a hinge connecting the first and second members and defining an axis of rotation. The locking hinge assembly includes a hinge element slidable along the axis of rotation between a locked position and an unlocked position. The hinge element is coupled to the forward handle member and the rear handle member at the hinge, and the hinge element includes at least one groove. Additionally, a locking element is provided and positioned about the hinge. The locking element is configured to be received in the groove such that rotation of the forward handle member and rear handle member about the axis of rotation is prevented when the hinge element is in the locked configuration.
    Type: Application
    Filed: August 27, 2013
    Publication date: December 26, 2013
    Applicant: Mallinckrodt LLC
    Inventor: Shawn P. Fojtik
  • Patent number: 8608693
    Abstract: A medicine injection device comprises a cartridge having a cartridge barrel and a plunger having a plunger shaft slidable within the cartridge barrel. The cartridge may have, e.g., a pre-filled medicine. The medicine injection device farther comprises a body having a proximal end, a distal end, and a cavity in which the cartridge barrel is disposed. The proximal end of the body may optionally form a finger grip. The medicine injection device further comprises a plunger locking mechanism attached to the proximal end of the body. The plunger locking mechanism comprises a member with an aperture slidably engaged with the plunger shaft. The locking mechanism is configured for preventing the plunger from being removed from the cartridge barrel. For example, the plunger shaft may include a locking stop, e.g., a flange, that engages with the aperture in an interference arrangement.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: December 17, 2013
    Assignee: Safety Syringes, Inc.
    Inventor: Lars Tommy Westbye
  • Publication number: 20130296799
    Abstract: A method of securing an assembly of a drug delivery system, comprising: configuring at least a first component and a second component of the assembly in a closed configuration ready for placement into the drug delivery system; installing an assembly key including a locking element on the assembly to secure the assembly in said configuration; and, transporting the assembly with the assembly key installed
    Type: Application
    Filed: April 30, 2013
    Publication date: November 7, 2013
    Inventor: MEDIMOP Medical Projects Ltd.
  • Patent number: 8568359
    Abstract: The invention relates to an autoinjector (1) comprising: a housing (30, 30a, 30b), a container movable within said housing between an initial position and an insertion position, said movement being prevented when the container is in its passive state, and permitted when the container is in its active state, and a safety shield (40) movable with respect to said housing between a first position and a second position, said movement placing the container in its active state, first retaining means (61, 52) for maintaining said container in its passive state, characterized in that it comprises first deactivating means (50, 51), capable of rotating with respect to said first retaining means from a first position, in which said first retaining means maintain said container in its passive state, to a second position, in which said first retaining means allow the passage of said container in its active state, said rotation being caused by movement of said safety shield from its first position to its second position
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: October 29, 2013
    Assignee: Becton Dickinson France
    Inventors: Franck Carrel, Frederic Perot
  • Patent number: 8545512
    Abstract: An intraocular insertion device capable of safely performing discharge operation of a lens by a simpler construction. The intraocular lens insertion device has a body provided with a lens placement section where the lens is placed and a tube section for inserting the lens into an eye and has a plunger for discharging the lens placed on the lens placement section. The lens placement section has an upper holding member and a lower holding member. The upper holding member has a rib projecting on advancement axis A, to the lower side of the lens placement section. The lower holding member has a U-shaped cross-section and is constituted of a left and right pair of uprising sections and a pressing section uniting the uprising sections at their lower ends.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: October 1, 2013
    Assignee: Hoya Corporation
    Inventors: Takashi Ichinohe, Kazunori Kudoh
  • Patent number: 8535277
    Abstract: The present disclosure relates to devices for use in conjunction with a syringe in measuring a dose using the syringe. In certain embodiments, a clip is provided that includes an elongated portion for insertion into a barrel of a syringe and a locking portion that locks onto a feature of the syringe. Once inserted, the clip physically prevents retraction of a plunger of the syringe past a certain point corresponding to a desired dose.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: September 17, 2013
    Assignee: William Marsh Rice University
    Inventors: Maria Oden, Julia Ellen Davidson Lukomnik, Cindy M. Dinh, Amanda Michelle Guiterrez, Carlos Amaro, Rebecca R. Richards-Kortum
  • Patent number: 8535278
    Abstract: An extendible plunger rod for use with a syringe is provided. Example plunger rods may include an outer plunger rod with a proximal end and a distal end, the outer plunger rod having an inner cavity; an inner plunger rod, housed at least partially within the inner cavity of the outer plunger rod; a compression spring disposed within the inner cavity of the outer plunger rod and between the proximal end of the outer plunger rod, and the inner plunger rod, the compression spring configured to exert force tending to push the inner plunger rod in a direction distal to the outer plunger rod; and a locking mechanism, the locking mechanism configured to prevent movement of the inner plunger rod relative to the outer plunger rod while both the inner and outer plunger rods are depressed into a syringe body, until the outer plunger rod has been depressed at least a first predetermined distance into the syringe body.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: September 17, 2013
    Assignee: Allergan, Inc.
    Inventor: Christopher S. Mudd
  • Patent number: 8529503
    Abstract: The present invention relates to a medicament delivery device comprising a generally elongated housing comprising a proximal part (10) and a distal part (12); a medicament cartridge (18) comprising a proximal opening closed by a septum (30), an axially movable distal stopper (26), and a first enclosure (20) wherein a liquid and a gaseous fluid are enclosed; a medicament delivery member (36) attachable to said proximal part (10) and having a non-delivery end (34); a medicament cartridge holder (16) wherein the medicament cartridge is coaxially arranged, said cartridge holder being arranged coaxially movable inside said proximal part and comprising holding means (38, 40) capable of holding said medicament cartridge holder (16) in a non-activated position in which said cartridge holder is releasebly engaged to said proximal part and in which a predetermined distance is present between the septum and the non delivery end; a manual pressure mechanism arranged to be moved from a non-pressure position to a pressure
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: September 10, 2013
    Assignee: SHL Group AB
    Inventors: Gunnar Elmén, Sebastian Karlsson
  • Patent number: 8529517
    Abstract: A syringe includes a cartridge and a second chamber. The cartridge includes a first chamber, a first end having a conduit in liquid communication with the first chamber, a liquid disposed within the first chamber, a second end moveable within the first chamber, and a locking mechanism. The conduit is adapted and configured to rely on a property of the liquid to prevent movement of the liquid out of the first chamber. The locking mechanism is adapted to prevent movement of the second end within the first chamber while in the locked configuration. The cartridge is moveable within the second chamber.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: September 10, 2013
    Assignee: Shi Zi Technology, Ltd.
    Inventor: Martin N. Lee
  • Patent number: 8529510
    Abstract: The present invention relates to an injection device comprises a generally elongated tubular housing having opposite proximal and distal ends; a needle shield sleeve slidably and coaxially arranged inside the housing and protruding a distance outside the proximal end of the housing; a syringe carrier mechanism comprising a syringe carrier slidably and coaxially arranged to the needle shield sleeve, wherein said syringe carrier comprises a syringe having a medicament and a needle; a first activator member slidably and coaxially arranged to the housing and connected to said needle shield sleeve; an actuating member slidably and coaxially arranged to the first activator member; a drive mechanism slidably and coaxially arranged to the actuating member and to the syringe carrier mechanism, said drive mechanism being controlled by the actuating member; a second activator member slidably and coaxially arranged to the distal end of the housing and fixedly connected to the actuating member; wherein the first and the s
    Type: Grant
    Filed: July 5, 2010
    Date of Patent: September 10, 2013
    Assignee: SHL Group AB
    Inventors: Lucio Giambattista, Antonio Bendek
  • Publication number: 20130204195
    Abstract: The invention relates to a transmission arrangement for controlling a force of a translation, the transmission arrangement comprising a drive collar (13) connectable to a translative drive means (11) and prevented from rotating with respect to a ground (12) of the drive means (11), a flange face of the drive collar (13) bearing against a mating flange face of a friction collar (20), the friction collar (20) slidable in longitudinal direction and rotationally constrained by engagement in a cam track (12.3), another flange face of the friction collar (20) bearing against a mating flange face of a plunger (8), the plunger (8) slidable in longitudinal direction and prevented from rotating.
    Type: Application
    Filed: February 16, 2011
    Publication date: August 8, 2013
    Applicant: SanofiI-Aventis Deutschland GmbH
    Inventors: Matthew Ekman, Timothy Donald Barrow-Williams, Thomas Mark Kemp
  • Patent number: 8500693
    Abstract: The present invention relates to a device for automatic injection of a product, comprising: a body (3) housing a container, the container being movable relative to said body between an initial position, to an insertion position; a safety shield (26) movable with respect to said container and said body between an insertion position to a protection position, when the user removes the device from an injection site; an external socket (48) receiving the body and provided with selection means (53) which can be placed by a user: either in a first position, in which the body (3) and the external socket (48) are bound to each other, the safety shield extending beyond the distal end of both said body and said external socket in the protection position; or in a second position, in which the external socket (48) is able to move axially in the distal direction with respect to the body (3), both the safety shield and the external socket extending beyond the distal end of said body, in the protection position.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: August 6, 2013
    Assignee: Becton Dickinson France
    Inventor: Lionel Maritan
  • Patent number: 8491538
    Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: July 23, 2013
    Assignee: TecPharma Licensing AG
    Inventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
  • Patent number: 8475415
    Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: July 2, 2013
    Assignee: Becton, Dickinson and Company
    Inventors: Eric Schiller, Michael V. Quinn, Johanna Torres, E Guan, Anthony Economou, Gang Ju
  • Patent number: 8475414
    Abstract: A medication delivery device (1) comprises a housing (4) having a proximal end (P) and a distal end (D), a cartridge (3) for holding a medication (M), the cartridge (3) having an outlet (2), a moveable piston (5) being retained within the cartridge (3), a drive member (17) moveable in a proximal direction with respect to the housing (4) for setting a dose of medication (M) to be delivered and in the distal direction with respect to the housing (4) for delivering the dose and a piston rod (10) adapted to drive the piston (5) in a distal direction with respect to the cartridge (3) for delivering the dose. The drive member (17) is releasably coupled to the piston rod (10). The medication delivery device (1) further comprises a resilient member (21) which is arranged to move the drive member (17) in the proximal direction with respect to the housing (4) after dose delivery, thereby reducing pressure of the piston rod (10) on the piston (5).
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: July 2, 2013
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Malcolm Boyd, Robert Veasey, David Plumptre
  • Patent number: 8469233
    Abstract: The application relates to a dispensing device (1) containing at least one chamber (5, 5?) for receiving a fluid (B, B?), a plunger unit (6) including at least one piston (7, 7?), locking mechanism and counter-locking mechanism as well as a catching mechanism and counter-catching mechanism. The locking mechanism and the counter-locking mechanism can be brought into a locking position (L), in which a movement of the plunger unit (6) in one or both directions is substantially prevented. The catching mechanism and the counter-catching mechanism can be brought into an engagement position (E), in which the locking mechanism and the counter-locking mechanism cannot be brought into the locking position (L). Furthermore, the application relates to a kit (19) containing the dispensing device (1) and to a method of operating the device (1) or kit (19).
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: June 25, 2013
    Assignee: Kuros Biosurgery AG
    Inventors: Peter Lutz, Annemie Rehor
  • Publication number: 20130158486
    Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes at least one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has a first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.
    Type: Application
    Filed: March 4, 2013
    Publication date: June 20, 2013
    Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AG
    Inventor: ROCHE DIAGNOSTICS INTERNATIONAL AG
  • Patent number: 8460250
    Abstract: A medical container including a gasket. Before liquid is injected and discharged (first state), sufficient air-tightness and liquid-tightness are maintained by strong force of fitting of an elastic ring member, fitted on a large diameter part of a gasket body member, relative to a circular tube body. When liquid is injected and discharged (second state), which is a state in which the elastic ring member has been slid from the large diameter part of the gasket body member to a position where the elastic ring member is fitted on the small diameter part of the gasket body member, the fitting force of the elastic ring member, fitted on the small diameter part of the gasket body member, relative to the circular tube body is smaller than the fitting force before liquid is injected and discharged (first state). The construction reduces sliding resistance of the gasket against the circular tube body.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: June 11, 2013
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Masaomi Imai
  • Publication number: 20130123712
    Abstract: A plunger rod includes: an elongated body formed by a plurality of orthogonally spaced elongated ribs extending along a longitudinal axis; a first ledge adjacent a first end of the elongated body; a second ledge adjacent a second end of the elongated body; and an attachment portion extending from the second ledge. The second end of the elongated body opposes the first end of the elongated body. At least one elongated rib includes a retaining anchor positioned adjacent the second end adjacent the second ledge.
    Type: Application
    Filed: November 6, 2012
    Publication date: May 16, 2013
    Applicant: Becton, Dickinson and Company
    Inventor: Becton, Dickinson and Company
  • Publication number: 20130085454
    Abstract: Provided is a reversible disposable resin needle for blood vessels. The reversible disposable resin needle for blood vessels is decreased in the total length compared with conventional resin needles while preventing exposure to the outside of a cylinder tube which forms the outer container when a piston tube consisting of a metallic needle is pushed back, and thus can reduce manufacturing costs and improve the convenience of storage, distribution, and handling.
    Type: Application
    Filed: March 10, 2011
    Publication date: April 4, 2013
    Inventors: Gyeong-Jin Song, Yeong-Sik Song, Won-Gi Song, Heon Chae, Jung-Sik Song, In-Jeong Song, Je-Wan Chae, Won-Chan Song
  • Publication number: 20130082057
    Abstract: A syringe assembly including a syringe barrel having a first end, a second end, and a sidewall extending therebetween defining a chamber is disclosed. The syringe assembly includes a stopper disposed within the chamber of the syringe barrel and a plunger rod having an inner member engaged with the stopper and an outer member adapted for telescopic movement with respect to the inner member. The plunger rod is transitionable from a collapsed position, in which a portion of the inner member is nested within the outer member, to an extended position, in which the same portion of the inner member extends outside the outer member. The syringe assembly also includes a stop member configured for cooperation with a portion of the syringe barrel, upon relative movement of the outer member with respect to the inner member, to limit the outward travel of the plunger rod from the syringe barrel.
    Type: Application
    Filed: September 19, 2012
    Publication date: April 4, 2013
    Applicant: BECTON DICKINSON FRANCE, S.A.S.
    Inventor: Becton Dickinson France, S.A.S Depler Le Pont-de-Claix
  • Patent number: 8409150
    Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes at least one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has a first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: April 2, 2013
    Assignee: Roche Diagnostics International AG
    Inventors: Ruedi Zihlmann, Ronny-Patric Horisberger, Daniel Fehlmann
  • Patent number: 8409141
    Abstract: The present application relates to a disposable auto injector (10) that can be safely operated for automatic injection of a dose of medication and having a housing (12) for accommodation of a syringe (18) with a needle (20), the syringe being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing (22), a driver configured for applying a force to the syringe thereby moving the syringe from the first position to the second position, and wherein the driver is also configured for applying a force to the syringe thereby moving the syringe from the second position to a retracted position in which position the needle is accommodated inside the housing upon user operation of a release member (42).
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: April 2, 2013
    Assignee: Bang & Olufsen Medicom A/S
    Inventors: Esben Weldingh Johansen, Jørgen Rasmussen, Christian Maegaard, Jørn Winther Hald
  • Publication number: 20130066279
    Abstract: The present invention relates to a piston rod assembly for a drug delivery device, comprising: a piston rod adapted to be operably engaged with a piston of a cartridge containing a medicament, at least one adjusting member displaceably disposed at the piston rod with respect to the piston rod's long axis, and being interconnected with a distal end section of the piston rod, and at least one interlock means adapted to interact with the adjusting member and/or with the piston rod for mutually locking in position the adjusting member and the piston rod in an arbitrary relative position in order to compensate for tolerances of manufacture and/or of assembly.
    Type: Application
    Filed: March 31, 2011
    Publication date: March 14, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Michael Helmer, Christoph Eisengarthen, Winfried Huthmacher, Carsten Mosebach, Leo Zeimetz
  • Publication number: 20130060202
    Abstract: A replaceable needle assembly is provided for a retractable syringe comprising a barrel and a plunger, whereby the retractable needle can be replaced by a user without affecting the retraction mechanism. A mounting member is removably mountable to the barrel by way of a screw-thread connection and a needle mount is removably coupled to the mounting member. A needle is mounted to the needle mount. The barrel comprises a needle mount retainer that comprises a plurality of fingers that engage the retractable needle mount to prevent inadvertent retraction. The plunger comprises a collapsible seal which maximizes the efficiency of fluid delivery prior to the plunger engaging the retractable needle mount for retraction. An initially compressed spring decompresses to drive retraction of the plunger and the engaged needle mount. A lock formed between the plunger and barrel prevents further use of the plunger after retraction.
    Type: Application
    Filed: November 11, 2010
    Publication date: March 7, 2013
    Applicant: UNITRACT SYRINGE PTY LTD
    Inventors: Craig Stephen Thorley, Joseph Hermes Kaal, Ian Johnson, Andrew Reade, Eric Siu, Richard Sokolov, Christopher Dunn
  • Patent number: 8361035
    Abstract: A retractable syringe, plunger and releasable needle retaining assembly are provided. The retractable syringe typically has a glass barrel and is prefilled with fluid contents before use. The releasable needle retaining system comprises a retractable needle, a needle seal, a retaining member and an ejector member that is operable to release the retractable needle from the retaining member. The retaining member has a mating surface for mounting to a complementary mating surface of an interior wall of a syringe barrel. The plunger comprises a plunger outer, a plunger rod frangibly connected to a controlling member, a spring and a unitary plunger seal capable of engaging the retractable needle, wherein the plunger rod, plunger outer and the controlling member co-operate to releasably maintain the spring in an initially compressed state. After delivery of fluid contents of the syringe, the plunger forces the ejector member to release the retractable needle from the retaining member.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: January 29, 2013
    Assignee: Unitract Syringe Pty Ltd.
    Inventors: Craig Stephen Thorley, Joseph Hermes Kaal, Chris Rafferty, Richard Sokolov, Ernesto Hueso, Huw Wallis, Steve Chi Truong
  • Publication number: 20130018328
    Abstract: The present invention relates to a piston for a cartridge for a drug delivery device comprising: at least one annular sealing surface to radially abut against an inner side wall of a cartridge, a distal surface to confine a drug receiving volume of the cartridge, a thrust receiving surface adapted to receive a thrust exerting plunger of a drug delivery device for displacing the piston in a proximal direction relative to the side wall, wherein the thrust receiving surface comprises numerous centering elements protruding from the thrust receiving surface towards the plunger and wherein the centering elements comprise an outer shape and geometry that matches with a corresponding receptacle of the plunger, and wherein the centering elements are arranged and aligned on the circumference of an imaginary annular or circular structure.
    Type: Application
    Filed: December 16, 2010
    Publication date: January 17, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Michael Jugl, Martin Otten
  • Publication number: 20130012888
    Abstract: A gasket of a prefilled syringe is disclosed, which includes a gasket body and a plunger-mounting member. The gasket body has a plunger-mounting member removal prevention rib formed on an inner surface of the gasket body. The plunger-mounting member has an outer projected part, which engages the plunger-mounting member removal prevention rib of the gasket body, a plurality of elastically deformable inner projected parts which are extended obliquely from an inner portion of a proximal side of the plunger-mounting member toward a central and distal end of the plunger-mounting member, and plunger removal prevention locking parts formed at free ends of the inner projected parts. The plunger has a distal end part capable of entering the plunger-mounting member and an outer projection part which engages the plunger removal prevention locking parts of the plunger-mounting member.
    Type: Application
    Filed: September 15, 2012
    Publication date: January 10, 2013
    Applicant: Terumo Kabushiki Kaisha
    Inventor: Hitoshi Okihara
  • Patent number: 8317751
    Abstract: An injection device (110) is provided which includes a syringe (122) having a discharge nozzle (118). The syringe is movable between a retracted position in which the discharge nozzle is contained within the housing and an extended position in which the discharge nozzle extends from the housing. A trigger (114) is activatable to allow the contents of the syringe to be discharged through the discharge nozzle. There is also a releasable locking mechanism (116) which, when engaged, prevents the trigger from moving into an active position. The trigger includes a first portion (150) having a cut-out (152) which extends from a first end of the trigger in a direction substantially parallel to the first axis (101). The releasable locking mechanism includes a protrusion (154) along a second axis (181) for communicating with the first portion of the trigger when the releasable locking mechanism is engaged and for communicating with the cut-out when the releasable locking mechanism is disengaged.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: November 27, 2012
    Assignee: Cilag GmbH International
    Inventors: Rosemary Louise Habeshaw, Jonathan Hogwood
  • Patent number: 8308726
    Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: November 13, 2012
    Inventors: Atul Kumar, Alka Kumar
  • Patent number: 8287491
    Abstract: A single-use auto-disable syringe device of reduced size utilizes a locking element to prevent re-use of the syringe by locking the plunger rod with respect to the barrel upon completion of an injection stroke. The plunger rod includes a plurality of teeth comprising distally facing shoulders provided on a majority of the length of an elongate portion of the plunger rod and a breakable section configured to break upon the application of excessive axial or torsional force. The breakable section is preferably provided at a distal end of the plunger rod so that a proximal end of the locking element engages the syringe barrel and plunger rod at a position more proximal than the breakable section. In this way, the locking element resists some of the force that would otherwise be applied to the breakable section if the plunger rod were twisted.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: October 16, 2012
    Assignee: Becton, Dickinson and Company
    Inventors: Steven Burns, Russell Cole, Chee L. Lum, David Martinez Llanos, Michael Soltz, Ramon Arazo Urraca, Luis Saldana
  • Patent number: 8267903
    Abstract: A casing for an injection device of the type having a safety device which prevents operation of the device, incorporating an actuator means by which the safety means of the device can be actuated to allow operation of the device. Also a casing for a medicament container having an opening closed prior to use by a break-off tip, having relatively moveable first and second casing parts, which on relative movement apply a breaking force to the break-off tip. A preferred embodiment includes both such features.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: September 18, 2012
    Assignee: Zogenix, Inc.
    Inventors: Gregor John McLennan Anderson, John Mitchell
  • Patent number: 8267902
    Abstract: A syringe including a front end and a rear end. A front portion of the syringe having an axially extending hollow needle that projects from the front end. The rear end of the needle is in fluid communication with a space that extends substantially to the rear end of the syringe. A plunger extends axially and is movable to and fro in the space and is designed such that, when drawn out, it sucks liquid through the needle and, when pressed in, discharges liquid through the needle. A radially projecting flange element in the front portion of the syringe is designed in such a way that it can be gripped between the thumb and middle finger of a user's hand. The syringe is dimensioned so as to permit injection using the index finger of the same hand. A capsule device for at least partially accommodating a syringe. A syringe device.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: September 18, 2012
    Assignee: Insulution Svenska AB
    Inventor: Patrick Martinsson
  • Publication number: 20120232492
    Abstract: A risk of injection liquid contamination due to contact of injection liquid in an injection-liquid filled area in a barrel with the surface in an injection-liquid unfilled area in the barrel by causing a plunger of a prefilled syringe to be inadvertently withdrawn by mishandling which may leads to medical malpractice, is eliminated by the invention. Withdrawal of a plunger 14 is limited by engagement of a barrel 12 in which a withdrawal-limiting member 48 is provided and a the plunger 14 in which a withdrawal-limiting member 54 is provided. As a result of this, contact of the injection liquid L prefilled to a liquid-filled area 32 in the barrel 12 with the surface of a liquid-unfilled area 34 in the barrel by withdrawal of the plunger 14 is prevented.
    Type: Application
    Filed: May 1, 2012
    Publication date: September 13, 2012
    Applicants: KYOWA HAKKO KIRIN CO., LTD., BECTON, DICKINSON AND COMPANY
    Inventor: Seiichi Hato
  • Publication number: 20120220952
    Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes a one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has as first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.
    Type: Application
    Filed: May 9, 2012
    Publication date: August 30, 2012
    Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AG
    Inventors: Ruedi Zihlmann, Ronny-Patric Horisberger, Daniel Fehlmann
  • Publication number: 20120197213
    Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.
    Type: Application
    Filed: October 27, 2011
    Publication date: August 2, 2012
    Inventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
  • Patent number: 8197451
    Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes a one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has as first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: June 12, 2012
    Assignee: Roche Diagnostics International AG
    Inventors: Ruedi Zihlmann, Ronny-Patric Horisberger, Daniel Fehlmann
  • Patent number: 8167837
    Abstract: A retractable syringe (11) and plunger (20) therefore are provided, whereby the plunger comprises a controlling means (62) which facilitates control of the rate of retraction of the retractable needle. By controlling the rate of needle retraction, the likelihood of blood spattering is reduced, thereby improving the user-friendliness and appeal of the retractable syringe. Typically, the syringe is a prefilled syringe. Following plunger depression, a symmetrical ejector member (92) releases the retractable needle (40) from a retaining member (30) to thereby allow retraction of the retractable needle. Needle retraction is facilitated by a biasing means (70), such as a spring or other compressible and/or de-compressible device. The plunger comprises a plunger housing (21), in which is located the controlling means. The controlling means may be a pneumatic air space (324) inside the plunger housing which automatically acts against the retracting needle to thereby control or regulate the rate of retraction.
    Type: Grant
    Filed: April 18, 2006
    Date of Patent: May 1, 2012
    Assignee: Unitract Syringe Pty Ltd.
    Inventors: Damien Judd, Joseph Hermes Kaal, Craig Stephen Thorley
  • Patent number: 8137324
    Abstract: A syringe includes a syringe cylinder, a sealing plug movably disposed within the syringe cylinder, and with a plunger cooperating with the sealing plug. A safety device prevents a sliding back of the sealing plug within the syringe cylinder in any position the sealing plug assumes within the syringe cylinder. The safety device has a locking element which engages at the plunger in any position the plunger assumes within the syringe cylinder. The locking element is attached to a retaining fixture and protrudes from the retaining fixture same such that an attachment point of the locking element is closer to the sealing plug at the retaining fixture than the free end of the locking element opposite of the attachment point.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: March 20, 2012
    Assignee: Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg
    Inventor: Benjamin Bobst
  • Patent number: 8128613
    Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: March 6, 2012
    Assignee: Safety Syringes, Inc.
    Inventors: James M. Verespej, Philip Dowds