Seal Ring Mounted On Piston Patents (Class 604/222)
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Patent number: 11975176Abstract: The present disclosure relates to a syringe including a container, for containing a primary fluid, and at least one secondary fluid chamber configured to contain a secondary fluid. The container comprises a proximal end and a distal end and having a distal end opening at the distal end. The syringe further comprises a stopper, movably arranged within the container; and a plunger engageable with the stopper and configured to apply a force to the stopper to move the stopper within the container towards the distal end of the container, to expel primary fluid from the container through the distal end opening. The plunger is further configured to expel secondary fluid from the at least one secondary fluid chamber towards the distal end opening, to expel at least a portion of a residual volume of primary fluid through the distal end opening. A plunger system and assembly for a syringe and methods of expelling fluid from a syringe are also disclosed.Type: GrantFiled: September 30, 2022Date of Patent: May 7, 2024Assignee: Numedico Technologies (IP) Pty LtdInventors: Brett Hoe Slater, Gregory James Roger
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Patent number: 11945204Abstract: An elastomeric article for sealing a container includes an elastomeric body having an external sidewall surface and an external crown surface and a first fluoropolymer film layer having an internal surface and an external surface. The internal surface of the first fluoropolymer film layer is laminated to an entirety of the external sidewall and crown surfaces of the elastomeric body. The external crown surface of the first fluoropolymer film layer includes a drug contact surface configured to contact a drug contained in the container and the external sidewall surface including a sealing surface for contacting an interior surface of the container. The external surface of the first fluoropolymer film layer is substantially free of striations.Type: GrantFiled: April 5, 2022Date of Patent: April 2, 2024Assignee: West Pharmaceutical Services, Inc.Inventors: Jason Krizan, Douglas R. Duriez, Liang Fang, Kerry Drake
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Patent number: 11872379Abstract: A drug delivery device with a housing configured to connect to a dispensing unit including a compartment containing a fluid, a piston rod configured to move in a proximal direction for ejecting the fluid, and a dosing mechanism including an actuation member to be actuated by a user. The device includes a conversion mechanism configured to convert a movement of the actuation member to a movement of the piston rod. The conversion mechanism includes a dose selector member, which is rotationally fixed to the housing and axially movable with respect to the housing, and a dosing member, which is rotationally movable with respect to the dose selector member. The drug delivery device includes a friction reduction mechanism provided between the dose selector member and the dosing member to reduce friction between the dose selector member and the dosing member.Type: GrantFiled: September 10, 2021Date of Patent: January 16, 2024Assignee: MEDMIX SWITZERLAND AGInventors: Heiko Müller, Wouter Reubzaet, André Hild
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Patent number: 11730885Abstract: In one embodiment, an injector includes a sleeve, a drive assembly, and a drive assembly housing. The sleeve is configured to receive a reservoir having a plunger therein. The drive assembly is configured to pressurize the reservoir and includes a tip, an actuator, and mechanical segments. The tip is configured to be secured to the plunger. The actuator is configured to supply a motive force to the tip for moving it between retracted and extended positions. The mechanical segments are configured to transmit motive force from the actuator to the tip. The drive assembly housing has a housing length in a direction parallel to a central longitudinal axis of the tip. The reservoir has a reservoir length L. A package length is defined by the housing length and the reservoir length L. The package length is less than 2L.Type: GrantFiled: May 14, 2021Date of Patent: August 22, 2023Assignee: ACIST Medical Systems, Inc.Inventor: Judson A. Herrig
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Patent number: 11717610Abstract: An injection device for injecting medicament in a patient comprises a housing configured to house a fluid reservoir that has one of a plurality of volumes of medicament. An injection conduit fluidly coupled to the fluid reservoir defines a fluid pathway from the fluid reservoir to the patient. A firing mechanism is coupled to the fluid reservoir and is configured to expel the medicament from the fluid reservoir through the injection conduit. A volume setting mechanism is coupled to the firing mechanism and is configured to select the one of the plurality of volumes of medicament for the firing mechanism to expel. A dose setting mechanism is configured to select all or a fraction of the one of the plurality of volumes of medicament that is injected from the injection conduit when the firing mechanism is actuated.Type: GrantFiled: May 21, 2020Date of Patent: August 8, 2023Assignee: ANTARES PHARMA, INC.Inventors: Bryan James Sarkinen, Michael Travanty, Patrick Madsen, Andrew Charles Mork
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Patent number: 11707576Abstract: A plunger gasket with reduced surface contact area including a body, a first side defining a first side surface, a second side defining a second side surface, and at least one surface feature projecting outwardly from at least one of the first or second side surfaces. In example embodiments, at least one surface feature projects outwardly from both the first and second side surfaces. By reducing the surface areas of contact between gaskets during manufacture and processing, the incidence of unintentional cohesion may be reduced or eliminated.Type: GrantFiled: September 19, 2019Date of Patent: July 25, 2023Assignee: Avent, Inc.Inventors: Benjamin M. Davis, David A. Doornbos
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Patent number: 11589786Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.Type: GrantFiled: March 31, 2022Date of Patent: February 28, 2023Assignee: Magnolia Medical Technologies, Inc.Inventors: Gregory J. Bullington, Richard G. Patton, Shan E. Gaw
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Patent number: 11446442Abstract: A gasket suitable for a syringe stopping with vacuum is provided. The gasket is compatible with sliding property within the sleeve and water-tightness of the syringe barrel after exiting the sleeve. The gasket includes a gasket body made of a liquid-resistant hard plastic having a tip surface contacting medicinal solution and a concave groove formed on a side surface facing an inner peripheral surface of a syringe barrel and formed continuously to the tip surface contacting medicinal solution; and a sliding contact ring made of an elastic material fitted in the concave groove. Then, an outer diameter D1 of a peripheral end of a tip portion including the tip surface contacting medicinal solution of the gasket body is set to be larger than the outer diameter D4 of the sliding contact ring.Type: GrantFiled: August 29, 2017Date of Patent: September 20, 2022Assignee: COKI ENGINEERING INC.Inventor: Akira Yotsutsuji
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Patent number: 11413401Abstract: To prevent accidental needle stick injuries, a syringe has a plunger configured to pull the syringe needle into the syringe barrel after clinical use. The syringe has an additional safety feature that restricts subsequent movement of the plunger. After the needle is pulled entirely into the barrel, movement of the plunger is restricted by a notch on the barrel to prevent the needle tip from being pushed accidentally through the barrel wall.Type: GrantFiled: March 7, 2019Date of Patent: August 16, 2022Assignee: QATAR UNIVERSITYInventors: Faris Tarlochan, Sami Alkhatib
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Patent number: 11344304Abstract: A device for closing a tissue opening includes a proximal housing portion having a first portion, a second portion, a third portion, and a fourth portion. The first portion and the fourth portion extending transversely to a longitudinal axis of the proximal housing portion on opposite sides of the proximal housing portion. A distal portion extends from the proximal housing portion. At least the second portion and the third portion are configured to move toward the first portion.Type: GrantFiled: September 27, 2018Date of Patent: May 31, 2022Assignee: ABBOTT LABORATORIESInventors: Erik K. Walberg, Timothy C. Reynolds, Brian A. Ellingwood, Kai Yenkai Jair, Anthony J. Pantages
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Patent number: 11331434Abstract: The present invention relates a botulinum toxin prefilled syringe system with desirable injection force characteristics, in particular low gliding force and low break loose force, comprising a syringe barrel of glass containing a liquid botulinum toxin composition, a plunger stopper and a closure device such as a tip cap or a needle shield. In addition, the present invention relates to a kit comprising the botulinum toxin prefilled syringe system, and optionally instructions for use, and to the use of the botulinum toxin prefilled syringe system in therapeutic and cosmetic applications.Type: GrantFiled: June 20, 2017Date of Patent: May 17, 2022Assignee: MERZ PHARMA GMBH & CO. KGAAInventor: Markus Vogt
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Patent number: 11318256Abstract: Injection device comprising a housing having an insertion opening at its distal end, a syringe carrier arranged within said housing, an actuation sleeve that is slidably arranged in the housing, first and second energy accumulating members, a plunger holder that is operationally associated with the first energy accumulating member and the syringe carrier, and a plunger rod that is slidably arranged in relation to plunger holder and to the syringe carrier, the plunger rod being operationally associated with the second energy accumulating member.Type: GrantFiled: March 29, 2017Date of Patent: May 3, 2022Assignee: SHL MEDICAL AGInventor: Oscar Alexandersson
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Patent number: 11040144Abstract: A plunger assembly (200) for use in a syringe apparatus (100). The plunger assembly (200) includes a movable tip (280) that can be removably secured to a plunger rod (210). By positioning the movable tip (280) in a barrel (300) while air (70) can still pass through a hole (282) in the movable tip (280), a user (90) can use the plunger assembly (200) to easily remove air (70) from a syringe apparatus (100) that has been loaded with the desired liquid (80).Type: GrantFiled: September 13, 2017Date of Patent: June 22, 2021Inventor: Shao Ma
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Patent number: 11027070Abstract: Disclosed herein is a pharmaceutical syringe having a cylindrical bore with a proximal opening, the syringe comprising a distal wall of the bore defining an outlet biased from the central axis of the syringe, and toward a first area of the distal wall and biased from the central axis away from a second area distinct from the first area; the syringe comprising a plunger seal having a distal surface; wherein when the plunger seal is fitted into the bore with the distal surface facing an inner surface of the distal wall of the bore, the second area of the inner surface is axially closer to the distal surface of the plunger seal than the first area, in a direction parallel to the central axis of the cylindrical bore, such that fluid is expelled from the second area and towards the outlet.Type: GrantFiled: October 10, 2016Date of Patent: June 8, 2021Assignee: WEST PHARMA SERVICES IL, LTDInventor: Oz Cabiri
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Patent number: 10987469Abstract: Finger control handles for conventional syringes are disclosed. The finger control handles may be configured to be assembled with a hand-held syringe, to be secured in place on a proximal portion of the barrel of the syringe and, when secured in place, to rotate freely about a circumference of the proximal portion of the barrel of the syringe. Systems that include the finger control handles and a hand-held syringe that is configured to capture the finger control handles are also disclosed, as are various methods of use, including methods for assembling the finger control handles with the syringe and methods for connecting the syringe to an elongated medical instrument, such as a catheter.Type: GrantFiled: September 25, 2015Date of Patent: April 27, 2021Assignee: PMT Partners, LLCInventor: Shawn P. Fojtik
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Patent number: 10912897Abstract: A single-use medical syringe having a plunger with a sealing element arranged on a distal end of the plunger head to contact the medicament in the syringe body and one or more hollow piercing elements disposed in the interior of the syringe body between a distal surface of the interior and the sealing element of the plunger head, wherein the one or more hollow piercing elements are arranged axially with respect to the syringe and positioned to be driven though the sealing element when the sealing element is driven against the distal surface at the end of the injection operation, wherein, at the end of the injection operation, the one or more hollow piercing elements create a fluid passageway across the plunger head when the one or more hollow piercing elements pierce through the sealing element of the plunger head.Type: GrantFiled: May 2, 2018Date of Patent: February 9, 2021Inventor: Indumathi Prakash
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Patent number: 10850085Abstract: Embodiments of the invention are directed to flush syringe assemblies comprising an integrated contamination-prevention device integrated with device connector flushing positioned so that the practitioner cannot forget to apply disinfectant. The flush syringe assemblies comprise a barrel with an elongate plunger rod disposed therein and a cap comprising a passageway. The plunger rod includes a stopper of which at least a portion can be embedded in the passageway of the cap to form a plug in the cap.Type: GrantFiled: June 26, 2018Date of Patent: December 1, 2020Assignee: Becton, Dickinson and CompanyInventor: Girum Yemane Tekeste
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Patent number: 10821238Abstract: An intradermal injection needle is an intradermal injection needle assembly to be used by piercing the intradermal injection needle into the skin of a living body. The intradermal injection needle has a hollow needle having a blade edge pierceable into the skin and a discharge port of an administration product; and a hub holding the hollow needle. The hollow needle has an outer diameter of 0.15 to 0.20 mm. The discharge port has a length of 0.10 to 0.80 mm in an axial direction of the hollow needle. When the intradermal injection needle is pierced into the skin of the living body, the discharge port thereof is entirely subcutaneously pierceable within a range of 0.20 to 1.00 mm.Type: GrantFiled: January 12, 2018Date of Patent: November 3, 2020Assignee: TERUMO KABUSHIKI KAISHAInventors: Takehiro Ura, Kiyoshi Sakata, Sakiko Tsuneda, Kazunori Koiwai
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Patent number: 10786430Abstract: The disclosure relates to a medicament delivery device, comprising a medicament cartridge adapted to contain a medicament and a stopper slidably arranged within the cartridge. The stopper-comprises a rigid body that is enclosed partially by a soft sealing component.Type: GrantFiled: January 15, 2016Date of Patent: September 29, 2020Assignee: Sanofi-Aventis Deutschland GMBHInventors: Michael Schabbach, Daniel Auernhammer, Christoph Dette
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Patent number: 10751473Abstract: A gasket (10) is used for a medical syringe (30), and includes a main body (11) made of an elastic material and an inert resin film (12) provided on a surface of the main body (11). The gasket (10) has a cylindrical shape, and includes a plurality of annular ribs (13, 14, 15) provided on an outer circumferential surface (20) thereof and each having a sliding contact portion (16) to be kept in sliding contact with an inner peripheral surface of a syringe barrel. The plurality of annular ribs are axially arranged from a distal end to a rear end of the gasket (10). The sliding contact portion (16) of a distal annular rib (13) has a width that is 1 to 25% of axial length of the cylindrical gasket.Type: GrantFiled: March 16, 2017Date of Patent: August 25, 2020Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.Inventors: Yoshikazu Masuyama, Hiroaki Nakano
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Patent number: 10722432Abstract: A plunger for movably mounting within a cavity or barrel of a syringe. The plunger includes a contact face having a flange movably mounted thereto, wherein the flange is movable between an open configuration wherein an opening is formed between the flange and a portion of the plunger, the opening configured for engagement with an IV hook or other engagement member, and a closed configuration wherein the upper surfaces of the contact face and the flange are generally planar with one another.Type: GrantFiled: February 22, 2017Date of Patent: July 28, 2020Assignee: NeoMed, Inc.Inventor: Benjamin M. Davis
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Patent number: 10710007Abstract: A filtration container assembly generally includes an outer container having a first end and a second end and defining an inner cavity, and a plunging assembly configured to be received within the outer container inner cavity, wherein the plunging assembly includes an inner sleeve having a first end and a second end and an outer wall defining an inner bore, wherein the outer wall is continuous from the first end to the second end, and a filtration assembly coupled to the inner sleeve at the second end.Type: GrantFiled: June 25, 2013Date of Patent: July 14, 2020Assignee: Grayl Inc.Inventors: Nancie Weston, Travis Merrigan, Michael Bargiel
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Patent number: 10661011Abstract: A safety syringe (100; 700; 1200) comprising: a barrel (104; 704; 1204) having an opening at an end thereof; a syringe plunger (108; 708; 1208) configured to move within the barrel such that an inward stroke of the syringe plunger causes a substance within the barrel to be expelled from the opening; and a sheath (112; 712; 1212) configured to cover at least partially the opening in the barrel after use of the syringe, wherein the sheath is coupled to the syringe plunger and is configured to decouple from the syringe plunger at a point on the inward stroke such that the sheath is moveable independently of the syringe plunger and further movement of the sheath after decoupling at least partially covers the opening in the barrel.Type: GrantFiled: March 6, 2018Date of Patent: May 26, 2020Assignee: Owen Mumford LimitedInventor: Damian Alexander Holland
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Patent number: 10653831Abstract: A medicament delivery device including a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further includes a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.Type: GrantFiled: October 27, 2014Date of Patent: May 19, 2020Assignee: Consort Medical, PLCInventors: Alastair Willoughby, Brad Howarth, Ian Anderson, Rachel Koppelman
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Patent number: 10632263Abstract: An apparatus and method for improving medication dosing is provided. The apparatus preferably includes a template configured to fit over a barrel of a syringe, the template having a substantially opaque exterior and at least one substantially transparent section in the substantially opaque exterior permitting a view of the syringe barrel and a distal end of a plunger within the barrel of the syringe. A method includes the steps of positioning a dosing template on a syringe, operating a plunger within the syringe, and drawing a predetermined dose of medication into the syringe.Type: GrantFiled: December 6, 2012Date of Patent: April 28, 2020Assignee: Becton, Dickinson and CompanyInventors: Artis Lockhart, Lawrence Monahan
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Patent number: 10598283Abstract: One aspect of the present disclosure relates to devices for sealing gaps in an extrusion assembly to provide for a consistent extrusion. In one embodiment, a barrel-shaped sealing device with a resilient protruding edge is used to prevent extrusion material from entering gaps between the piston and the inner surface of the barrel. The sealing device includes a fastener to releasably attach the sealing device to the piston. Sealing rings are inserted into a bottom gap formed between the bottom edge of the barrel and the bottom surface of the die.Type: GrantFiled: March 24, 2016Date of Patent: March 24, 2020Inventor: Dorothy Feibleman
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Patent number: 10391258Abstract: A setting mechanism for a dosing device, in particular for a device for dosing pharmaceutical or therapeutic substances, the setting mechanism including: a controlling assembly for connecting the setting mechanism with a dose setting element of the dosing device; a driving assembly for connecting the setting mechanism with a driving element of the dosing device; a dosing assembly for connecting the setting mechanism with a dosing element of the dosing device. The controlling assembly is coupled with the dosing assembly by a spring element, which can deform from a coupled position to a decoupled position during rotation of the dose setting element. The spring element is configured to allow a displacement of the controlling assembly with respect to the dosing assembly. In the coupled position the spring element is configured to block a rotation of the controlling assembly with respect to the dosing assembly.Type: GrantFiled: April 13, 2018Date of Patent: August 27, 2019Assignee: COPERNICUS SP. Z O.O.Inventors: Adam Stefanski, Mateusz Wilczek, Alberto Lozano Platonoff
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Patent number: 10376194Abstract: A device for the extraction of blood or a blood compound is provided that includes a tube, a piston assembly, a handle assembly that can be clipped to the piston assembly, and a perforable sealing element that prevents the flow of fluid from a sealed interior space of the tube towards a longitudinal interior cavity of the handle assembly located adjacent to a separable area of the handle assembly. In use, the handle assembly is pushed to the bottom of the tube, causing the handle assembly to be clipped to the piston assembly, the handle assembly and the piston assembly are then moved rearwards forming a vacuum in the space, the piston assembly is clipped to an end cap of the tube and the gripping portion of the handle assembly is separated, obtaining a vacuum container with a perforable closure.Type: GrantFiled: June 2, 2016Date of Patent: August 13, 2019Assignee: BIOTECHNOLOGY INSTITUTE, I MAS D, S.L.Inventor: Eduardo Anitua Aldecoa
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Patent number: 10369292Abstract: A syringe for storing and delivering a fluid that includes (1) a stopper and (2) a plunger rod assembly is provided. The plunger rod assembly includes a plunger rod and a threaded member at a plunger-engaging end. The stopper may be formed of an elastomeric material. The stopper has an exterior surface and an inner cavity. The inner cavity of the stopper may have a generally frustoconical shape with at least one engagement surface. The threaded member contacts at least one engagement surface in the inner cavity of the stopper to support the plunger rod assembly in an integrated, non-threaded engagement with the stopper. In some embodiments, the threaded member is freely rotatable within the inner cavity.Type: GrantFiled: January 12, 2017Date of Patent: August 6, 2019Assignee: W. L. Gore & Associates, Inc.Inventor: Erik M. LaRose
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Patent number: 10272196Abstract: Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.Type: GrantFiled: December 22, 2014Date of Patent: April 30, 2019Assignee: perQflo, LLCInventors: Roger E. Smith, James Causey, Scott R. Gibson
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Patent number: 10039886Abstract: A syringe sealing assembly includes a stopper coupling and a plunger coupling. The stopper coupling is adaptable to attach to a syringe stopper. The plunger coupling is releasably attachable to the stopper coupling. The stopper coupling is further adaptable to fit within a syringe barrel and to seal the interior of the syringe barrel from the external environment in cooperation with the syringe stopper. The plunger coupling is adaptable to attach to a syringe plunger. The plunger coupling is further adaptable to be received within a syringe barrel when the plunger coupling is attached to the stopper coupling. The plunger coupling is further adaptable to be withdrawn from the syringe barrel while the stopper coupling remains in the syringe barrel when the plunger coupling is detached from the stopper coupling.Type: GrantFiled: May 13, 2016Date of Patent: August 7, 2018Assignee: Black Tie Medical Inc.Inventors: Mary L. Pilkington, Mariano C. Riego de Dios
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Patent number: 9981089Abstract: The present invention provides a gasket for prefilled syringes having both airtightness and operability. The present invention relates to a gasket for prefilled syringes, the gasket including a plurality of circular ribs that are to be in sliding contact with the inner wall of a syringe, the gasket being laminated with an inert film, the plurality of circular ribs including a front circular rib having a front corner with a radius of curvature R1 and a rear corner with a radius of curvature R2, a ratio of the radius of curvature R2 to the radius of curvature R1 being more than 1.Type: GrantFiled: September 12, 2014Date of Patent: May 29, 2018Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.Inventors: Naoyuki Ishida, Kazuhiro Fujisawa
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Patent number: 9958067Abstract: A syringe for dispensing liquid materials to a substrate. In one embodiment, the syringe includes a barrel having a first end, a second end, and an interior reservoir. A piston is slidably disposed within the reservoir and is movable to increase or decrease a volume of the interior reservoir near the first end of the barrel. A first end of the piston has a hemispherically-shaped surface profile, with an elongated apex extending therefrom, to dispense liquid from the first end of the barrel when the piston is moved in a direction toward the first end.Type: GrantFiled: June 12, 2007Date of Patent: May 1, 2018Assignee: Nordson CorporationInventors: Warren N. Strong, Michael A. Vidal, Terrence Woldorf
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Patent number: 9925338Abstract: An injection system includes a syringe, which preferably includes larger and smaller inner diameters, and a plunger. A wiper sidewall of the plunger defines a cavity, into which a plunger shaft of the system is inserted, for moving the plunger, within the syringe, for fluid injection. The plunger includes a feature for engaging the shaft, and the sidewall preferably includes an expandable-contractible portion, in which the feature is formed. When the plunger is initially mounted within the larger inner diameter of the syringe, the portion of the sidewall is expanded and the feature of the plunger does not operably engage the inserted shaft. When the shaft moves the plunger into the smaller inner diameter of the syringe, the portion of the sidewall contracts and the feature operably engages the shaft. A deformable end wall of the plunger may be spaced apart from a distal terminal end of the inserted shaft.Type: GrantFiled: April 29, 2016Date of Patent: March 27, 2018Assignee: ACIST MEDICAL SYSTEMS, INC.Inventors: Martin G. Hieb, David J. Hajicek, Sidney D. Nystrom
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Patent number: 9850445Abstract: Provided are a sliding elastic body capable of imparting excellent sliding properties and resistance to protein adsorption and, at the same time, maintaining sealing properties; and a syringe gasket, a catheter, and a tire which include the sliding elastic body. The present invention relates to a sliding elastic body including an elastic body whose surface is fully or partially laminated with a fluororesin film, the laminated elastic body being treated with a fluorinated oil.Type: GrantFiled: January 6, 2014Date of Patent: December 26, 2017Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Yasuhisa Minagawa
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Patent number: 9642969Abstract: A stopper includes a main body portion defining an open rearward end configured to receive the plunger rod, an engagement portion provided along an inner circumference of the main body portion configured to engage at least a top portion of the plunger rod, a closed front end forming a flexible roof, and a first perimetrical skirt extending around an outer circumference of the main body portion toward the closed front end of the main body portion. When fluid pressure is increased inside the syringe barrel during an injection, the flexible roof expands in a radial direction toward an inner wall of the syringe barrel, the first perimetrical skirt is forced against the inner wall of the syringe barrel, and an engagement between the plunger rod and the engagement portion forces the main body portion to expand in the radial direction toward the inner wall of the syringe barrel.Type: GrantFiled: March 28, 2012Date of Patent: May 9, 2017Assignee: Becton, Dickinson and CompanyInventors: Milan Ivosevic, Girum Yemane Tekeste, Andrew Wong, Michael Vincent Quinn, Andrzej Baranski
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Patent number: 9579463Abstract: A syringe barrel includes an barrel main body having a cylinder tip at a distal end of the barrel main body; and a cap detachably attached to the cylinder tip by threaded engagement to seal an opening of the cylinder tip. The cylinder tip comprises at least one projection that projects radially from an outer periphery of a proximal end part of the cylinder tip. The cap includes a cylindrical cover that covers an outer periphery of the cylinder tip. A proximal-side inner periphery of the cover comprises a reduced radius portion, and, when the cap is threadedly engaged with the cylinder tip, a distance from a rotation axis of the cap to the reduced radius portion is smaller than a distance from the rotation axis to an outer end of the at least one projection.Type: GrantFiled: March 4, 2016Date of Patent: February 28, 2017Assignee: TERUMO KABUSHIKI KAISHAInventor: Hitoshi Okihara
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Patent number: 9572939Abstract: The present invention relates to a piston for a cartridge to be filled with a medicament, the piston comprising: a first piston member comprising a first material and forming a distal end face of the piston, a second piston member comprising a second material of lower compressibility compared to the first material, wherein the second piston member is arranged in a cupped receptacle of the first piston member and provides a thrust receiving surface at a proximal end of the piston.Type: GrantFiled: November 1, 2012Date of Patent: February 21, 2017Assignee: Sanofi-Aventis Deutschland GmbHInventors: Ramatullah Qurishi, Martin Otten, Stefan Trinkle, Jörn Möckel, Sebastian Thiel
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Patent number: 9539200Abstract: An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The fluid channel is adapted for delivery of an active agent formulation from the reservoir of the osmotic delivery system.Type: GrantFiled: February 26, 2015Date of Patent: January 10, 2017Assignee: Intarcia Therapeutics Inc.Inventors: Scott C. Lautenbach, Pedro E. De La Serna, Pauline C. Zamora, Michael A. Desjardin
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Patent number: 9539394Abstract: A method of making a syringe assembly includes providing a first syringe component defining a first sliding surface that is substantially free of lubricant. The first sliding surface is contacted with water. The first sliding surface and the water in contact with the first sliding surface are heated at a temperature of at least 121° C. The first sliding surface is dried.Type: GrantFiled: April 13, 2012Date of Patent: January 10, 2017Assignee: W. L. Gore & Associates, Inc.Inventor: Michael P. Moritz
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Patent number: 9446199Abstract: Syringes and methods of using are described which protect the syringe barrel cavity from contaminants. A first syringe is formed with a corrugated sheath which encloses the plunger and space between the rearward end face surface of the syringe barrel handle member and the forward face of the plunger handle member. A second syringe is formed with a syringe barrel having a straight segment and a corrugated segment having the forward face of the plunger handle member molded to the rearward terminus of the corrugated segment of the syringe barrel. A third syringe is formed from mating syringe barrel and plunger member walls. The walls of the mating syringe barrel and plunger member are concentric and slide relative to each other while maintaining an enclosure around the plunger shaft. A fourth syringe is formed from inner and outer concentric syringe barrel walls mating with the walls of a plunger member.Type: GrantFiled: October 15, 2010Date of Patent: September 20, 2016Inventor: Robin Scott Gray
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Patent number: 9415169Abstract: A gasket configured so that a pusher having a male screw thread on the outer periphery of its tip is connected to the gasket through the male screw thread and so that the gasket slides within a syringe outer tube when the pusher is operated in the longitudinal direction. The gasket includes: a gasket body having a hollow section and a female screw thread in the inner peripheral section of the hollow section engaged by the male screw thread; and projections on the outer peripheral section of the gasket body extending circumferentially of the outer peripheral section and axially arranged in spaced relation to each other. When the gasket is not yet inserted into the syringe outer tube, a screw thread located in a portion on the inner side of and in direct proximity to the projection has a smaller height than a screw thread located in the remaining portion.Type: GrantFiled: February 23, 2010Date of Patent: August 16, 2016Assignee: TERUMO KABUSHIKI KAISHAInventors: Kouichi Tachikawa, Junichi Ogawa
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Patent number: 9352105Abstract: An injection system includes a syringe, which preferably includes larger and smaller inner diameters, and a plunger. A wiper sidewall of the plunger defines a cavity, into which a plunger shaft of the system is inserted, for moving the plunger, within the syringe, for fluid injection. The plunger includes a feature for engaging the shaft, and the sidewall preferably includes a expandable-contractible portion, in which the feature is formed. When the plunger is initially mounted within the larger inner diameter of the syringe, the portion of the sidewall is expanded and the feature of the plunger does not operably engage the inserted shaft. When the shaft moves the plunger into the smaller inner diameter of the syringe, the portion of the sidewall contracts and the feature operably engages the shaft. An optional deformable end wall of the plunger may be spaced apart from a distal terminal end of the inserted shaft.Type: GrantFiled: November 19, 2013Date of Patent: May 31, 2016Assignee: ACIST Medical Systems, Inc.Inventors: Martin G. Hieb, David J. Hajicek, Sidney D. Nystrom
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Patent number: 9333301Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end with a passageway therethrough in fluid communication with the chamber. An elongate plunger having a proximal end, a distal end and a stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for drawing fluid into and out of the chamber by movement of the stopper relative to the barrel. The plunger includes anti-reflux structure for minimizing stopper deflection when fluid has been delivered from the chamber and the stopper is being forced against the distal end of the chamber.Type: GrantFiled: October 13, 2014Date of Patent: May 10, 2016Assignee: Becton, Dickinson and CompanyInventors: Thomas A. Alheidt, Tracy Ray Hottovy, James J. Timko
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Patent number: 9302048Abstract: A cylinder-piston unit, of a needle-free injector, with at least one cylinder accommodating an injection solution, and with at least one piston. The piston is composed of a drive body and of a sealing body. The sealing body is at least one elastic disc, which bears under a radial clamping action against the inner wall of the cylinder. The drive body is a pot-shaped body with a peripheral elastic skirt. At least one area of the skirt bears under a radial clamping action against the inner wall of the cylinder. The cylinder chamber areas located in front of and behind the drive body communicate with each other via at least one recess. The drive body is arranged behind the sealing body in the cylinder, and the skirt faces towards the sealing body.Type: GrantFiled: May 13, 2014Date of Patent: April 5, 2016Assignee: LTS LOHMANN THERAPIE-SYSTEME AGInventor: Rudolf Matusch
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Publication number: 20150148753Abstract: A syringe having a syringe body defining an elongate cavity therein with a non-circular internal cross-sectional profile, and a syringe plunger operable to selectively travel within the hollow cavity with a non-circular external cross-sectional profile that substantially mirrors the syringe body's internal cross-sectional profile for mating engagement thereof. The enteral syringe may also have venting features and support features for hanging from a support structure.Type: ApplicationFiled: February 4, 2015Publication date: May 28, 2015Applicant: NEOMED, INC.Inventors: Aaron N. INGRAM, Benjamin Martin DAVIS, Anthony C. LAIR, Mark Martin COSTELLO, Tony DOHERTY
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Publication number: 20150141935Abstract: A dispenser assembly is provided that has a rigid plunger with a ring-shaped protrusion. The protrusion contacts the inner wall of a flexible barrel to form a liquid-tight seal. Advantageously, the dispenser assembly does not require additional components, such as o-rings, and can be fabricated by injection molding techniques.Type: ApplicationFiled: November 18, 2014Publication date: May 21, 2015Inventor: David Young
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Publication number: 20150133873Abstract: A gasket for use in a syringe so formed as to liquid-tightly and slidably contact an inner surface of an outer cylinder of the syringe, the gasket including a gasket body made of an elastic body and a coating layer formed in a portion thereof which contacts at least the syringe, wherein the coating layer includes a composition containing silicone resin which includes a condensate of reactive silicone resin having a terminal silanol group and which has a siloxane bond derived from the silanol group, and does not contain solid fine particles.Type: ApplicationFiled: January 20, 2015Publication date: May 14, 2015Applicant: Terumo Kabushiki KaishaInventors: Aiko HORIUCHI, Eiji WATANABE, Shigeru SUZUKI, Masami SHIMODA
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Publication number: 20150105736Abstract: A plunger cover for use with a syringe includes a sealing portion adapted to form a seal with the syringe and a central portion adapted to contact fluid within the syringe. The central portion can, for example, be more rigid than the sealing portion. The sealing portion and the central portion are connected in an overmolding process. The sealing portion can, for example, be formed from a thermoplastic elastomer or a thermoplastic polyurethane. The central portion can, for example, be formed from polypropylene, acrylonitrile butadiene styrene, polycarbonate or copolymers thereof.Type: ApplicationFiled: December 19, 2014Publication date: April 16, 2015Inventors: Joseph E. Bisegna, Jared E. Neff
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Patent number: 8992962Abstract: An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The fluid channel is adapted for delivery of an active agent formulation from the reservoir of the osmotic delivery system.Type: GrantFiled: May 20, 2013Date of Patent: March 31, 2015Assignee: Intarcia Therapeutics Inc.Inventors: Scott D. Lautenbach, Pedro E. de la Serna, Pauline C. Zamora, Michael A. DesJardin