Seal Ring Mounted On Piston Patents (Class 604/222)
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Publication number: 20150032064Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end with a passageway therethrough in fluid communication with the chamber. An elongate plunger having a proximal end, a distal end and a stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for drawing fluid into and out of the chamber by movement of the stopper relative to the barrel. The plunger includes anti-reflux structure for minimizing stopper deflection when fluid has been delivered from the chamber and the stopper is being forced against the distal end of the chamber.Type: ApplicationFiled: October 13, 2014Publication date: January 29, 2015Inventors: Thomas A. Alheidt, Tracy Ray Hottovy, James J. Timko
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Publication number: 20140350484Abstract: An injection device having a delivery element with an inner thread may be driven by rotation and includes a cylindrical outer wall region, which is substantially smooth. Such features provide a delivery element configured such that it is less intimidating to patients than known threaded rods, and may facilitate easy cleaning. The delivery element may be non-rotatably guided and axially spring-loaded, and may be inserted axially into the housing when the reservoir is replaced. The driving thread element for the delivery element may be mounted in the vicinity of the distal end of the housing.Type: ApplicationFiled: August 8, 2014Publication date: November 27, 2014Inventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
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Publication number: 20140288509Abstract: A syringe for a high-pressure injector, having a syringe cylinder with a tube connection for a tube line located at an end closer to the patient and having a plunger that is guided inside the syringe cylinder in an advancing direction and that has sealing surfaces for resting in a sealed fashion against an inner wall of the syringe cylinder. The plunger is embodied as a two-component injection-molded part based on thermoplastic plastic with a core piece composed of a harder plastic and a covering layer that is mounted on the core piece and is composed of a comparatively softer material. The covering layer constitutes or forms at least the sealing surfaces and the plunger surface of the plunger oriented toward the end of the syringe cylinder closer to the patient. The plunger is embodied with or has openings in the region of its plunger surface.Type: ApplicationFiled: October 16, 2012Publication date: September 25, 2014Inventors: Hanno Altmeyer, Gotthilt Mehner
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Publication number: 20140288507Abstract: A self-locking syringe assembly is disclosed. The syringe assembly includes a barrel having an interior surface. An elongate plunger shaft is axially moveable within the barrel. The plunger shaft includes at least two longitudinally extending splines. A stopper is attached to the distal tip of the plunger shaft which provides a fluid-tight seal with the barrel. Tabs are positioned at annularly spaced locations on the interior surface of the barrel. The tabs extend radially inwardly from the sidewall a predetermined distance and define recesses therebetween for receiving the plunger splines during axial movement of the plunger shaft within the barrel. The splines include recesses to enable rotational movement of the plunger shaft when the recesses are axially aligned with the tabs to dispose the splines against the tabs. In this manner, the plunger shaft may be locked in a predetermined longitudinal position relative to the barrel.Type: ApplicationFiled: May 17, 2013Publication date: September 25, 2014Inventor: Bensson Samuel
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Publication number: 20140288508Abstract: The present invention aims to provide a pre-filled syringe coated with a resin film capable of reducing sliding resistance and preventing liquid leakage by a simple method. The present invention relates to a gasket for a pre-filled syringe, which has a sliding side surface that is coated with an inactive resin film and further cut to form a cut. The cut region is preferably between ring-shaped ribs on the sliding side surface, or in a ring-shaped rib on the sliding side surface.Type: ApplicationFiled: March 3, 2014Publication date: September 25, 2014Applicant: Sumitomo Rubber Industries, Ltd.Inventors: Shinya IWANO, Katsushi MAEDA
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Patent number: 8821440Abstract: An injection device has a dispensing chamber housing, a plunger, and a temperature control device. The dispensing chamber housing has a first part and a second part. The first part is thermally coupled to a needle. The second part is thermally coupled to the first part. The second part has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with an inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering a temperature of the substance in the dispensing chamber. The second part has a greater thermal coefficient than the first part.Type: GrantFiled: July 13, 2007Date of Patent: September 2, 2014Assignee: Alcon Research, Ltd.Inventors: Robert Sanchez, James Foster, Cesario Dos Santos
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Publication number: 20140228774Abstract: The present invention aims to provide a gasket for a pre-filled syringe which has excellent air-tightness and liquid-tightness and a mold for forming the gasket. The present invention relate to a mold for a gasket laminated with an inactive film for a pre-filled syringe, wherein at least a surface of the mold which forms a seal sliding surface of an annular protrusion of the gasket is mirror finished to have an arithmetic mean roughness Ra of less than 0.03 ?m.Type: ApplicationFiled: April 3, 2014Publication date: August 14, 2014Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventors: Katsushi MAEDA, Junji TASHIRO, Hiroaki NAKANO, Eiji YAO
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Patent number: 8801700Abstract: An osmotic delivery system is disclosed for delivering an active agent formulation to a fluid environment. The osmotic delivery system typically comprises a reservoir having a lumen that contains the active agent formulation and an osmotic agent formulation and a piston assembly positioned in the lumen to isolate the active agent formulation from the osmotic agent formulation. The piston assembly typically comprises a body constructed and arranged for positioning in the lumen. The body is typically made of a polymeric material that is, for example, resistant to leaching in an organic solvent. In one embodiment, the body is a columnar body having a rim at a distal end thereof for engaging and sealing against a wall of the reservoir and the piston assembly further comprises a spring retained at the distal end of the columnar body for biasing the rim of the columnar body against the wall of the reservoir.Type: GrantFiled: January 19, 2011Date of Patent: August 12, 2014Assignee: Intarcia Therapeutics, Inc.Inventors: Thomas R. Alessi, Michael A. DesJardin, Stan Lam, Scott D. Lautenbach, Pauline C. Zamora
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Publication number: 20140207081Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.Type: ApplicationFiled: March 25, 2014Publication date: July 24, 2014Inventors: Michael Vincent Quinn, Eric Schiller, Gang Ju, E. Guan
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Patent number: 8740856Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.Type: GrantFiled: April 5, 2010Date of Patent: June 3, 2014Assignee: Becton, Dickinson and CompanyInventors: Michael Vincent Quinn, Eric Schiller, Gang Ju, E Guan
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Publication number: 20140135708Abstract: Medical articles with coatings are disclosed herein, as well as methods and systems for depositing these coatings onto medical articles. Surfaces of such articles may be coated. The coating(s) may serve as lubricants for reducing suction between such surfaces or between a coated surface and another surface.Type: ApplicationFiled: January 17, 2014Publication date: May 15, 2014Applicant: GVD CorporationInventors: Hilton G. Pryce Lewis, Neeta P. Bansal, Erik S. Handy
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Publication number: 20140081214Abstract: An injection system includes a syringe, which preferably includes larger and smaller inner diameters, and a plunger. A wiper sidewall of the plunger defines a cavity, into which a plunger shaft of the system is inserted, for moving the plunger, within the syringe, for fluid injection. The plunger includes a feature for engaging the shaft, and the sidewall preferably includes a expandable-contractible portion, in which the feature is formed. When the plunger is initially mounted within the larger inner diameter of the syringe, the portion of the sidewall is expanded and the feature of the plunger does not operably engage the inserted shaft. When the shaft moves the plunger into the smaller inner diameter of the syringe, the portion of the sidewall contracts and the feature operably engages the shaft. An optional deformable end wall of the plunger may be spaced apart from a distal terminal end of the inserted shaft.Type: ApplicationFiled: November 19, 2013Publication date: March 20, 2014Applicant: ACIST MEDICAL SYSTEMS, INC.Inventors: MARTIN G. HIEB, DAVID J. HAJICEK, SIDNEY D. NYSTROM
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Patent number: 8574201Abstract: A fluid syringe of the type used with fluid infusion devices is presented here. The fluid syringe generally includes a barrel, a piston, and a check valve seal. The barrel has an interior wall and a sealed main fluid chamber. The piston is slidably coupled within the barrel, and the piston has a piston seal forming an interference fluid seal against the interior wall. The check valve seal is coupled to the piston, and it is located between the piston seal and the main fluid chamber. The check valve seal forms an interference fluid seal against the interior wall when the piston is unloaded, and it disengages the interior wall to allow gas flow from the main fluid chamber toward the piston seal when the piston is loaded.Type: GrantFiled: December 17, 2010Date of Patent: November 5, 2013Assignee: Medtronic Minimed, Inc.Inventors: Sarnath Chattaraj, Poonam S. Gulati, Lance P. Hoffman, Kiem Dang
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Publication number: 20130274682Abstract: A locking syringe with an integrated bias member, for delivering medical fluids at high pressure, can include a housing, a shaft, a piston, a cap assembly, a bias member, and a locking member. A distal end of the housing can interface with a patient delivery apparatus. The housing includes an internal cavity into which a distal end of the shaft can be inserted. The piston can be connected to the distal end of the shaft and can include a peripheral sealing surface that can slidably engage the inside surface of the housing to form a movable seal. The cap assembly at the proximal end of the housing can engage the shaft. A base cap can secure the piston within the housing. The bias member can have a distal end coupled to the piston and a proximal end restrained, such as to help pressurize the internal cavity. The user-actuatable locking member can user-selectively engage and inhibit unwanted movement of the shaft.Type: ApplicationFiled: February 28, 2013Publication date: October 17, 2013Inventors: Yunxing Liu, Chun Li
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Publication number: 20130253436Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.Type: ApplicationFiled: May 8, 2013Publication date: September 26, 2013Inventors: Eric Schiller, Michael Vincent Quinn, Johanna Torres, E Guan, Anthony Economou, Gang Ju
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Patent number: 8535278Abstract: An extendible plunger rod for use with a syringe is provided. Example plunger rods may include an outer plunger rod with a proximal end and a distal end, the outer plunger rod having an inner cavity; an inner plunger rod, housed at least partially within the inner cavity of the outer plunger rod; a compression spring disposed within the inner cavity of the outer plunger rod and between the proximal end of the outer plunger rod, and the inner plunger rod, the compression spring configured to exert force tending to push the inner plunger rod in a direction distal to the outer plunger rod; and a locking mechanism, the locking mechanism configured to prevent movement of the inner plunger rod relative to the outer plunger rod while both the inner and outer plunger rods are depressed into a syringe body, until the outer plunger rod has been depressed at least a first predetermined distance into the syringe body.Type: GrantFiled: November 11, 2010Date of Patent: September 17, 2013Assignee: Allergan, Inc.Inventor: Christopher S. Mudd
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Patent number: 8474656Abstract: A syringe has a dripless feature by using an O-ring located between a conical disc and a flat plunger disc in an annular groove on a moving plunger. The flat plunger disc has a series of projections that offset the o-ring off the flat plunger disc surface when the plunger is not actuated. When the plunger is actuated, the o-ring distorts to rest on the projections and also on the surface of the flat plunger disc. When the plunger is released, the o-ring's resiliency pulls the o-ring back to its original shape which sucks back the fluid being dispensed so that no or less drips occur.Type: GrantFiled: June 25, 2007Date of Patent: July 2, 2013Assignees: Kuraray Noritake Dental Inc., Yoshino Kogyosho Co., Ltd.Inventors: Hideto Kunishi, Yasujiro Ohara, Katsuhito Kuwahara, Toru Toma, Satoshi Sakamoto
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Patent number: 8475415Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.Type: GrantFiled: June 4, 2008Date of Patent: July 2, 2013Assignee: Becton, Dickinson and CompanyInventors: Eric Schiller, Michael V. Quinn, Johanna Torres, E Guan, Anthony Economou, Gang Ju
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Patent number: 8470353Abstract: An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The fluid channel is adapted for delivery of an active agent formulation from the reservoir of the osmotic delivery system.Type: GrantFiled: January 12, 2013Date of Patent: June 25, 2013Assignee: Intarcia Therapeutics, Inc.Inventors: Scott D. Lautenbach, Pedro E. de la Serna, Pauline C. Zamora, Michael A. DesJardin
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Publication number: 20130158486Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes at least one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has a first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.Type: ApplicationFiled: March 4, 2013Publication date: June 20, 2013Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AGInventor: ROCHE DIAGNOSTICS INTERNATIONAL AG
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Publication number: 20130150800Abstract: The invention relates to an auto-injector with an interlock mechanism for defining an operation sequence of the auto-injector (1) in a manner to allow a lateral trigger button (16) to be operated only when a proximal end (P) of the auto-injector (1) is pressed against an injection site, wherein a detector means (18) is arranged inside an elongate housing (2) of the auto-injector (1) at the proximal end (P), the detector means (18) slidable in longitudinal direction and biased by a detector spring (19) into a position with the detector means (18) protruding beyond the proximal end (P), wherein a dog (16.2) is arranged at the trigger button (16) and wherein at least one longitudinal bar (18.1, 21) is provided, at least one of the bars (21) slidable in longitudinal direction and coupled to the detector means (18) for joint movement at least in distal direction (D), wherein a recess (21.1) for the dog (16.Type: ApplicationFiled: March 3, 2011Publication date: June 13, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Thomas Mark Kemp, Douglas Jennings, Peter Scudamore, Matthew Ekman
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Publication number: 20130082058Abstract: A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed.Type: ApplicationFiled: September 19, 2012Publication date: April 4, 2013Applicant: BECTON DICKINSON FRANCE, S.A.S.Inventor: Becton Dickinson France, S.A.S.
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Publication number: 20130079729Abstract: A needle does not come off even if a high back pressure occurs at the skin upper section. Thus, the drug leakage from the skin can be prevented. A drug administration device 1 includes a tubular section 2 having a fluid chamber 7 capable of accommodating a drug and a discharge section 22, a pusher member 3 moving within the tubular section 2, a grip section 4, and a connection section 5. The pusher member 3 includes a rod-shape plunger 31 and a gasket 32. The grip section 4 is disposed along the outer periphery of the tubular section 2 and kept away from the tubular section 2, and the connection section 5 is formed between the tubular section 2 and the grip section 4.Type: ApplicationFiled: March 2, 2011Publication date: March 28, 2013Applicant: TERUMO KABUSHIKI KAISHAInventors: Takayuki Yokota, Yoichiro Iwase, Naoki Sakaguchi, Kazunori Koiwai, Yoshinori Hishikawa
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Patent number: 8394069Abstract: A unidirectional injector having at least one cylinder-piston unit, the piston thereof being displaceable between two stroke end positions relative to the cylinder, wherein the cylinder-piston unit comprises at least one sealing system sealing a compensating space from the surroundings. To this end the piston is provided at its front surface with an axial annular groove for accommodating a seal ring or a permanently elastic seal material, that the cylinder is provided with a first seal element and a second seal element which are spaced by at least a piston stroke, or that the piston is provided with the first seal element and the second seal element which are spaced by at least a piston stroke, or the cylinder carries the first seal element and the piston carries the second seal element which is displaced with respect to the first by the piston stroke.Type: GrantFiled: June 3, 2011Date of Patent: March 12, 2013Assignee: LTS Lohmann Therapie-Systeme AGInventor: Rudolf Matusch
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Publication number: 20130060202Abstract: A replaceable needle assembly is provided for a retractable syringe comprising a barrel and a plunger, whereby the retractable needle can be replaced by a user without affecting the retraction mechanism. A mounting member is removably mountable to the barrel by way of a screw-thread connection and a needle mount is removably coupled to the mounting member. A needle is mounted to the needle mount. The barrel comprises a needle mount retainer that comprises a plurality of fingers that engage the retractable needle mount to prevent inadvertent retraction. The plunger comprises a collapsible seal which maximizes the efficiency of fluid delivery prior to the plunger engaging the retractable needle mount for retraction. An initially compressed spring decompresses to drive retraction of the plunger and the engaged needle mount. A lock formed between the plunger and barrel prevents further use of the plunger after retraction.Type: ApplicationFiled: November 11, 2010Publication date: March 7, 2013Applicant: UNITRACT SYRINGE PTY LTDInventors: Craig Stephen Thorley, Joseph Hermes Kaal, Ian Johnson, Andrew Reade, Eric Siu, Richard Sokolov, Christopher Dunn
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Publication number: 20130060203Abstract: A syringe includes a cylindrical container in which is arranged at least a first piston which delimits a storage volume. The syringe is provided with at least one yielding element having a first side that delimits the storage volume in a liquid tight fashion, and having a second side that is in communication with the surroundings of the syringe. This renders the syringe liquid tight even if the pressure of the substance in the storage volume increases. This may be used when sterilizing with heat or when freeze drying substance in the syringe. The syringe can include a first piston with a first piston rod and a second piston with a second piston rod. The two pistons then define two storage volumes which may be used for storage of freeze dried substance and a solvent for the freeze dried substance, respectively.Type: ApplicationFiled: May 2, 2011Publication date: March 7, 2013Inventor: Jan Svensson
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Patent number: 8367095Abstract: An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The fluid channel is adapted for delivery of an active agent formulation from the reservoir of the osmotic delivery system.Type: GrantFiled: August 31, 2012Date of Patent: February 5, 2013Assignee: Intarcia Therapeutics, Inc.Inventors: Scott D. Lautenbach, Pedro E. de la Serna, Pauline C. Zamora, Michael A. DesJardin
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Publication number: 20130006215Abstract: A fluid dispensing device (10) for delivering a dose of fluid into a surgical site includes a tube (12) with a lumen (22) for receiving the dose of fluid, a housing (14) coupled to the tube, and a flexible plunger (24) at least partially disposed in the housing (14). The fluid dispensing device (10) also includes an actuation device (66, 140) engaging the flexible plunger (24) and a trigger (26) operable to cause the actuation device (66, 140) to move the flexible plunger (24). The actuation device (66, 140) may be toggled between a first operational mode in which movement of the trigger (26) advances the flexible plunger (24) into the lumen (22) and a second operational mode in which movement of the trigger (26) retracts the flexible plunger (24) from the lumen (22).Type: ApplicationFiled: March 24, 2011Publication date: January 3, 2013Applicant: NORDSON CORPORATIONInventors: Todd William Sharratt, Troy Allen Pongratz
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Patent number: 8322577Abstract: A plunger for a syringe used to inject gas and liquid chromatography samples has an end portion surrounded by a flexible sleeve. The sleeve forms a seal in the bore of a barrel traversed by the plunger, the bore being in fluid communication with a cannula attached to the end of the barrel. The plunger has an end surface that is exposed and is flush with an annular end surface of the sleeve. The plunger end surface, and not the sleeve, contacts the cannula upon injection and avoids imposing cyclical hoop stresses on the barrel which tend to crack the barrel after a finite number of cycles. In a further embodiment, a thin layer of sleeve material covers the end surface of the plunger. The thin layer avoids inducing significant barrel stress.Type: GrantFiled: April 24, 2009Date of Patent: December 4, 2012Assignee: Agilent Technologies, Inc.Inventor: Ponna Pa
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Patent number: 8308726Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.Type: GrantFiled: September 1, 2005Date of Patent: November 13, 2012Inventors: Atul Kumar, Alka Kumar
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Publication number: 20120277686Abstract: The sliding property at the inner peripheral surface of a syringe body is improved by means of a simple configuration, and smooth and stable slidability can be ensured for a gasket. A syringe (1) is equipped with a synthetic resin syringe body (3) for injecting a liquid (L), a plunger (5) for pushing out the liquid (L) that was injected into the syringe body (3), and a gasket (9) which is attached to the tip (7) of the plunger (8), wherein the inner peripheral surface (14) of the syringe body (3) is coated with a silicone, and is subjected to corona discharge treatment after the syringe body (3) is coated with silicone.Type: ApplicationFiled: April 30, 2012Publication date: November 1, 2012Applicant: Ajinomoto Co., Inc.Inventor: Yasuhiro MURAMATSU
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Publication number: 20120253292Abstract: A stopper includes a main body portion defining an open rearward end configured to receive the plunger rod, an engagement portion provided along an inner circumference of the main body portion configured to engage at least a top portion of the plunger rod, a closed front end forming a flexible roof, and a first perimetrical skirt extending around an outer circumference of the main body portion toward the closed front end of the main body portion. When fluid pressure is increased inside the syringe barrel during an injection, the flexible roof expands in a radial direction toward an inner wall of the syringe barrel, the first perimetrical skirt is forced against the inner wall of the syringe barrel, and an engagement between the plunger rod and the engagement portion forces the main body portion to expand in the radial direction toward the inner wall of the syringe barrel.Type: ApplicationFiled: March 28, 2012Publication date: October 4, 2012Applicant: BECTON DICKINSON AND COMPANYInventors: Milan Ivosevic, Girum Yemane Tekeste, Andrew Wong, Michael Vincent Quinn, Andrzej Baranski
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Publication number: 20120253291Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel includes a main body portion defining an open rearward end configured to receive the plunger rod. The main body portion is manufactured from a rigid or semi-rigid polymeric material having an elastic modulus in the range of about 0.01 GPa to about 5 GPa. When fluid pressure is increased inside the syringe barrel during an injection, at least one of the following actions occurs: a) a flexible roof of the main body portion expands in a radial direction toward an inner wall of the syringe barrel; b) a first perimetrical skirt extending around an outer circumference of the main body portion is forced against an inner wall of the syringe barrel; and c) an engagement between the plunger rod and an engagement portion provided along an inner circumference of the main body portion.Type: ApplicationFiled: March 28, 2012Publication date: October 4, 2012Applicant: BECTON DICKINSON AND COMPANYInventors: Milan Ivosevic, Girum Yemane Tekeste, Michael Vincent Quinn, Andrzej Baranski
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Publication number: 20120220952Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes a one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has as first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.Type: ApplicationFiled: May 9, 2012Publication date: August 30, 2012Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AGInventors: Ruedi Zihlmann, Ronny-Patric Horisberger, Daniel Fehlmann
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Publication number: 20120184920Abstract: A prefilled syringe has a gasket composed of a gasket body and a plunger-mounting member mounted. The plunger-mounting member has a distal part, spiral ribs formed on an outer surface of the distal part, a flange part, and a plunger-mounting part formed on an inner surface of a hollow part. The gasket body has a spiral screwing part which screws the spiral ribs and an accommodation part for accommodating a portion where the spiral ribs are formed. A plunger has a mounting distal part. The plunger-mounting part has a spiral concave portion and an engaging rib disposed at a side distal from the spiral concave portion. The mounting distal part of the plunger has a spiral projected portion capable of screwing the spiral concave portion and an engaging portion which engages the engaging rib of the plunger-mounting member.Type: ApplicationFiled: March 30, 2012Publication date: July 19, 2012Applicant: TERUMO KABUSHIKI KAISHAInventors: Hitoshi Okihara, Hideo Watanabe
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Publication number: 20120165755Abstract: Syringe pistons for a fluid syringe, and related sealing elements, are presented here. A syringe piston includes a piston body having a fluid end, an actuator end, and an outer seal-retaining surface between the fluid end and the actuator end. The syringe piston may utilize a piston sealing sleeve or a piston sealing cover. The sleeve can be coupled to the piston body around the outer seal-retaining surface, the piston sealing sleeve having a fin-shaped fluid seal element to form an interference fluid seal with an interior wall of a syringe barrel. The sealing cover can be coupled overlying the tip of the piston body. The cover has a fin-shaped fluid seal element to form an interference fluid seal with an interior wall of a syringe barrel.Type: ApplicationFiled: March 8, 2012Publication date: June 28, 2012Applicant: MEDTRONIC MINIMED, INC.Inventors: Sarnath CHATTARAJ, Poonam S. GULATI, Kiem DANG, Jocelyn Anne MONTEBON
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Publication number: 20120165754Abstract: Syringe pistons for a fluid syringe, and related sealing elements, are presented here. A syringe piston includes a piston body having a fluid end, an actuator end, and an outer seal-retaining surface between the fluid end and the actuator end. The syringe piston may utilize a piston sealing sleeve or a piston sealing cover. The sleeve can be coupled to the piston body around the outer seal-retaining surface, the piston sealing sleeve having a fin-shaped fluid seal element to form an interference fluid seal with an interior wall of a syringe barrel. The sealing cover can be coupled overlying the tip of the piston body. The cover has a fin-shaped fluid seal element to form an interference fluid seal with an interior wall of a syringe barrel.Type: ApplicationFiled: March 8, 2012Publication date: June 28, 2012Applicant: MEDTRONIC MINIMED, INC.Inventors: Sarnath CHATTARAJ, Poonam S. GULATI, Kiem DANG, Jocelyn Anne MONTEBON
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Patent number: 8167850Abstract: A cylinder/piston unit is disclosed for pre-fill, storage and release when desired of an active substance, such as a medicament. The cylinder/piston unit is provided with a cylinder and with a piston which is guided therein and which is sealed off in a sterile manner by a rubber seal, the cylinder and the piston enclosing a chamber that can be filled at least temporarily with active substance, and the cylinder having at least one discharge element at its front end. For this purpose, the piston resting in a rear position is sealed off relative to the cylinder in a sterile manner by a static front sealing element and by a static rear sealing element. Arranged spatially behind each static sealing element, there is a parking area for receiving the respective sealing element.Type: GrantFiled: February 26, 2009Date of Patent: May 1, 2012Assignee: LTS Lohmann Therapie-Systeme AGInventors: Hans-Rainer Hoffmann, Rudolf Matusch
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Patent number: 8137324Abstract: A syringe includes a syringe cylinder, a sealing plug movably disposed within the syringe cylinder, and with a plunger cooperating with the sealing plug. A safety device prevents a sliding back of the sealing plug within the syringe cylinder in any position the sealing plug assumes within the syringe cylinder. The safety device has a locking element which engages at the plunger in any position the plunger assumes within the syringe cylinder. The locking element is attached to a retaining fixture and protrudes from the retaining fixture same such that an attachment point of the locking element is closer to the sealing plug at the retaining fixture than the free end of the locking element opposite of the attachment point.Type: GrantFiled: August 10, 2006Date of Patent: March 20, 2012Assignee: Arzneimittel GmbH Apotheker Vetter & Co. RavensburgInventor: Benjamin Bobst
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Publication number: 20120016314Abstract: A gasket configured so that a pusher having a male screw thread on the outer periphery of its tip is connected to the gasket through the male screw thread and so that the gasket slides within a syringe outer tube when the pusher is operated in the longitudinal direction. The gasket includes: a gasket body having a hollow section and a female screw thread in the inner peripheral section of the hollow section engaged by the male screw thread; and projections on the outer peripheral section of the gasket body extending circumferentially of the outer peripheral section and axially arranged in spaced relation to each other. When the gasket is not yet inserted into the syringe outer tube, a screw thread located in a portion on the inner side of and in direct proximity to the projection has a smaller height than a screw thread located in the remaining portion.Type: ApplicationFiled: February 23, 2010Publication date: January 19, 2012Applicant: TERUMO KABUSHIKI KAISHAInventors: Kouichi Tachikawa, Junichi Ogawa
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Patent number: 8083716Abstract: Various embodiments of the present invention are directed to limiting a presence of air bubbles in a fluidic medium expelled from a reservoir. In various embodiments, a plunger head within a reservoir is shaped so as to limit a presence of air bubbles in a fluidic medium expelled from the reservoir. Also, in various embodiments, a reservoir is shaped so as to limit a presence of air bubbles in a fluidic medium expelled from the reservoir. In some embodiments, both a reservoir and a plunger head within the reservoir are shaped so as to limit a presence of air bubbles in a fluidic medium expelled from the reservoir.Type: GrantFiled: December 26, 2007Date of Patent: December 27, 2011Assignee: Medtronic Minimed, Inc.Inventors: Julian D. Kavazov, Sheldon B. Moberg, Ian B. Hanson, Colin A. Chong, Eric M. Lorenzen, Rafael Bikovsky, Truong Gia Luan, Mike Lee, Christopher G. Griffin, Thomas Miller
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Patent number: 8075523Abstract: Various embodiments of syringe assemblies include a syringe barrel and a substantially conical tip or outlet disposed on the distal end of the barrel. The substantially conical tip includes a locking mechanism that engages an extension of a plunger assembly extending from a distal end of the plunger assembly so as to retain the extension within the substantially conical tip or outlet upon full injection of the contents of the syringe to a patient. According to one embodiment, a plunger head of the plunger assembly is slidably disposed on the extension. According to another embodiment, a separate hub, which holds a needle cannula, is disposed on an outlet at the distal end of the syringe barrel, which contains the locking mechanism. According to a further embodiment, the locking mechanism includes a locking clip disposed within the substantially conical tip of the syringe assembly.Type: GrantFiled: June 26, 2009Date of Patent: December 13, 2011Assignee: Becton, Dickinson and CompanyInventors: Brian H. Wayman, Robert Odell, Richard James Caizza
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Patent number: 8048036Abstract: A hypodermic needle assembly configured such that the movement of a needle shield into position to block the needle tip occurs as a direct consequence of a longitudinal force applied by insertion of a syringe plunger is provided. The hypodermic needle assembly according to the present invention comprises a needle, a needle hub, and a safety spring clip assembly, the safety spring clip assembly being configured to automatically launch from the needle hub and slide along the needle until the spring clip meets a needle stop at the needle tip, thus preventing the guard from being removed from the needle shaft. A method of using the hypodermic needle assembly according to the present invention is also provided, which includes the method of launching the spring clip with a syringe having multiple advancing mechanisms.Type: GrantFiled: July 31, 2006Date of Patent: November 1, 2011Assignee: B. Braun Melsungen AGInventors: Kevin Woehr, Helmut Freigang, Juergen Fuchs, Juergen Reuter, Klaus Siemon, Joerg Wende, Frank Hilberg
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Patent number: 8043267Abstract: The prefilled syringe filled with a drug in advance, leaking of liquid from the cap is prevented, gas barrier properties are given to the whole of the barrel filled with the drug and the shoulder section so that degradation of the drug is prevented, permeation of microbial contaminants is prevented to a high extent, and efficiency of packing as a compact container can be increased. The prefilled syringe includes a guard-shaped extension projecting from the outer periphery of a shoulder section of the syringe barrel on the nozzle side, and a range from a part where a gasket of the plunger is positioned on the outer surface of the syringe barrel filled with the drug to the guard-shaped extension is covered with barrier packaging.Type: GrantFiled: August 18, 2006Date of Patent: October 25, 2011Assignee: Nipro CorporationInventors: Ryohei Nanba, Masanobu Iwasa, Mitsuru Hasegawa, Yoshihisa Murai
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Publication number: 20110238015Abstract: A unidirectional injector having at least one cylinder-piston unit, the piston thereof being displaceable between two stroke end positions relative to the cylinder, wherein the cylinder-piston unit comprises at least one sealing system sealing a compensating space from the surroundings. To this end the piston is provided at its front surface with an axial annular groove for accommodating a seal ring or a permanently elastic seal material, that the cylinder is provided with a first seal element and a second seal element which are spaced by at least a piston stroke, or that the piston is provided with the first seal element and the second seal element which are spaced by at least a piston stroke, or the cylinder carries the first seal element and the piston carries the second seal element which is displaced with respect to the first by the piston stroke.Type: ApplicationFiled: June 3, 2011Publication date: September 29, 2011Inventor: Rudolf Matusch
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Publication number: 20110224643Abstract: A pre-fill syringe with a receiver tube (1, 12, 21) with a nozzle (4, 20) positioned at the nozzle-side end of the receiving tube (1, 12, 21), the piston (2, 18) is to be formed in such a manner that it for a transport state at the nozzle-side end of the receiver tube (1, 12, 21) can be connected with the receiving tube.Type: ApplicationFiled: March 8, 2011Publication date: September 15, 2011Inventors: Eric Schliemann, Karl-Heinz Fuchs
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Patent number: 8007475Abstract: A flush syringe assembly comprises a barrel including a cylindrical side wall having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including an elongate tip extending distally therefrom having a passageway in fluid communication with the chamber. A plunger including an elongate body portion has a stopper at its distal end. The stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for driving fluid out of the chamber. The distal end of the stopper is configured to collapse while fluid is being driven though the passageway through motion of a plunger and to continue to drive fluid through the passageway after motion of the plunger has stopped.Type: GrantFiled: January 7, 2005Date of Patent: August 30, 2011Assignee: Becton, Dickinson and CompanyInventor: Anthony J. Kosinski
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Publication number: 20110208158Abstract: A kit and a method for delivering an injectable solution to a tissue treatment site are provided. The kit includes a housing having a chamber, a proximal portion and a distal portion. An injectable solution having a viscosity greater than about 10,000 cP is provided in the chamber. A plunger is provided in the proximal portion of the housing. The kit also includes a pressure gauge operably connected to the housing. The kit may also include a handle connected to the housing and a plunger advancing member having a plunger handle connected thereto provided separate from the housing. The kit may also include an inner shaft provided separate from the housing and having a proximal end portion configured for operably connecting with the distal portion of the housing for receiving the injectable solution therethrough and a distal end of the shaft configured for insertion in to the tissue treatment site.Type: ApplicationFiled: February 17, 2011Publication date: August 25, 2011Applicant: Cook Medical Technologies LLCInventors: John C. Sigmon, JR., Vihar C. Surti, Michael L. Williams
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Publication number: 20110178475Abstract: A plunger for a syringe, in which a plunger rod can be prevented by a simple structure from unavoidably falling out of place. The plunger for a syringe includes the plunger rod and a gasket. The gasket is closed at its upper end and has an inner space, and an opening having a diameter smaller than the diameter of the inner space is provided in the lower end of the gasket. The plunger rod has a collar installed at the tip of the plunger rod. When the collar is positioned in the inner space of the gasket, the plunger rod and the gasket are freely movably fitted together without intimate contact between them.Type: ApplicationFiled: July 31, 2006Publication date: July 21, 2011Inventors: Shigeki Tanaka, Masanobu Iwasa, Ryohei Namba, Hidero Kato, Teruhisa Hirobe
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Patent number: 7972301Abstract: A braking mechanism for a retractable safety syringe is disclosed herein. In a first embodiment, the braking mechanism is disposed about the distal end of a piston. The braking mechanism may comprise a friction material about a post attached to a piston. The friction material is displaced from a seat to a landing when the piston is traversed to a fully extended position to disengage the braking mechanism. In a second embodiment, the braking mechanism is disposed at a proximal end of a syringe body. The braking mechanism has a friction member which engages an outer surface of a rigid shaft of a plunger. The friction member is selectively pivotable to disengage the braking mechanism.Type: GrantFiled: March 27, 2007Date of Patent: July 5, 2011Assignee: Safeshot Technologies, LLCInventor: Richard B. Oliver