Removable Plug Patents (Class 604/238)
  • Patent number: 11779519
    Abstract: The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: October 10, 2023
    Inventors: Lynn E. Jensen, Venugopal R. Ghatikar, DeLoy Lindley, Melvin D. Jensen
  • Patent number: 11533857
    Abstract: A system for administering a fluid to a tree. The fluid can be water, coloring agents, insecticides, fungicides, nutrients, plant growth regulators and herbicides. The system also includes a pressurizable container containing the fluid and a low pressure gas. The pressurizable container is attached to a manifold. Additionally, an infusion nozzle is attached to the manifold and configured to provide attachment of the system to a tree for an extended period of time ranging from weeks to months. The system also can, optionally, include an infusion control valve configured to regulate the flow of fluid from the container, through the manifold, through the infusion nozzle and into the tree. The infusion nozzle has threads that provide direct attachment to the tree.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: December 27, 2022
    Inventor: Jeffrey J Bird
  • Patent number: 11517675
    Abstract: Described is a catheter patency maintenance device comprising of a flush syringe, an elongate plunger rod with a stopper slidably positioned within the barrel, a cap, disinfectant and a valve movable between an open position and a closed position. The valve may include a valve stem and/or openings in the valve to permit fluid flow. Methods of using the flush syringe assemblies are also described.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: December 6, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Girum Yemane Tekeste
  • Patent number: 11305064
    Abstract: A mixing vial having a hollow interior chamber with a tubular portion having distal and proximal open ends and a stopper positioned in sealing relationship in the tubular portion, the stopper having a hollow interior chamber with an open end and a dislodgeable plug positioned in and sealing the open end.
    Type: Grant
    Filed: January 2, 2018
    Date of Patent: April 19, 2022
    Assignee: Balanced Pharma Incorporated
    Inventor: John Scott Keadle
  • Patent number: 10765463
    Abstract: One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder and for delivering the bone cement paste, the device having a cartridge with a cylindrical interior, the interior of the cartridge being closed at the front side apart from a delivery opening for discharging the bone cement paste from the interior. A delivery plunger is arranged in the interior of the cartridge and mounted so as to be pushable in the direction of the delivery opening. The cement powder is arranged in the interior of the cartridge between the delivery opening and the delivery plunger. A closure closes the delivery opening and is mounted so as to be movable relative to the delivery opening. A line element is arranged at the front side of the delivery opening and includes a closure receptacle for receiving at least part of the closure.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: September 8, 2020
    Assignee: Heraeus Medical GmbH
    Inventors: Sebastian Vogt, Thomas Kluge
  • Patent number: 9802002
    Abstract: The present invention provides test or training a cartridge for a drug delivery device as well as a method for resetting of such cartridge, wherein the cartridge comprises: a body of substantially cylindrical shape, a piston slidably disposed in the body in an axial direction, a closure means disposed at an axial end portion of the body, wherein the body, the piston and the closure means confine an interior volume coupled to the exterior via at least one fluid escape channel.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: October 31, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Christopher James Smith
  • Patent number: 9351806
    Abstract: A dispensing device for a dental substance which has a container for receiving the dental substance, a piston movable in the container, a catch for engagement by an applicator, and further a resilient resilient adapter. The device may be used in different types of applicators and is relatively inexpensive.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: May 31, 2016
    Inventors: Helmut Pauser, Marc Peuker, Michael Knee, Werner Fichtl, Andreas Maurer
  • Publication number: 20150148775
    Abstract: A drug delivery device is provided for delivering a drug to a target tissue site. The drug delivery device comprises a body comprising a proximal end and a distal end and a chamber disposed therebetween. An upper portion is disposed about the proximal end of the body. A retaining member is disposed within a wall of the body and engageable with the chamber and a plunger is configured for disposal within the upper portion and the chamber. The upper portion is movable about the proximal end of the body to open the chamber such that the plunger is disposed within a passageway defined within the chamber, and movement of the plunger in a distal direction pushes the retaining member such that the drug moves out of the body. Methods are also disclosed.
    Type: Application
    Filed: October 17, 2014
    Publication date: May 28, 2015
    Inventors: Danielle L. Clay, Jeffrey C. Marx
  • Patent number: 8900179
    Abstract: A thrombectomy system may include an elongate shaft that defines a high pressure lumen and a low pressure lumen. The high pressure lumen may terminate near an end of the low pressure lumen. An expandable capture basket may be disposed near the end of the low pressure lumen. A thrombectomy apparatus may include an elongate shaft, an evacuation lumen extending within the elongate shaft and a high pressure lumen extending within the elongate shaft. A capture apparatus may be disposed within a wire lumen that extends within the elongate shaft such that the capture apparatus extends distally from the wire lumen.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: December 2, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Mark L. Jenson, William J. Drasler, Joseph M. Thielen
  • Patent number: 8852155
    Abstract: A medicine reservoir (10) is provided for use with a drug delivery device (50). The medicine reservoir (10) is arranged for comprising a drug (13) and comprises a dispensing hole (15) for dispensing the drug (13) into an environment of the drug delivery device (50). The medicine reservoir (10) further comprises a deformable plug (14) which plug (14) is removable by pressure caused by a dispensing action of the drug delivery device (50).
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: October 7, 2014
    Assignee: Medimetrics Personalized Drug Delivery
    Inventors: Hans Zou, Jeff Shimizu, Lucian Remus Albu
  • Publication number: 20140243750
    Abstract: System comprising a sensor assembly (3, 4, 5, 6) adapted to measure a magnetic field, and a moveable element (1) adapted to be moved relative to the sensor assembly between two positions by a combined axial and rotational movement, the rotational movement having a pre-determined relationship to the axial movement. A magnet (3) is mounted to the moveable element and configured to generate a spatial magnetic field which relative to the sensor assembly varies corresponding to both the axial and rotational movement of the magnet and thus the moveable element. A processor is configured to determine on the basis of measured values for the magnetic field an axial position of the moveable element.
    Type: Application
    Filed: October 5, 2012
    Publication date: August 28, 2014
    Applicant: NOVO NORDISK A/S
    Inventors: Andre Larsen, Henrik Riehm Soerensen, Laurits Hoejgaard Olesen, Nikolaj Frogner Krusell, Jens Christian Andersen
  • Patent number: 7641620
    Abstract: A sampling apparatus for taking a sample from the body of a patient is easily rotatable while the sample is being taken. This allows the physician to aspirate or draw the sample, rotating the sampling apparatus while holding stationary a syringe or other container for receiving the sample.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: January 5, 2010
    Assignee: Vance Products Incorporated
    Inventor: Troy W. Wingler
  • Patent number: 7488308
    Abstract: An injector with a substance container defining a substance chamber configured for containing a substance to be injected, and an injection conduit configured for injecting the substance into a patient. A driver is associated with the substance chamber for driving the substance through the injection conduit. The injector also has a channel member defining a channel that has an open configuration in which the channel fluidly communicates the substance container to the injection conduit for the injection of the substance. The channel also has a closed configuration for blocking flow of any substance in the substance container therethrough to the injection conduit for inhibiting or preventing contact with the injection conduit prior to injection.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: February 10, 2009
    Assignee: Antares Pharma, Inc.
    Inventor: Paul R. Lesch, Jr.
  • Patent number: 6497684
    Abstract: A syringe with a barrel for holding a fluid medium includes a sealing cap that is put on the outlet end of the barrel. The barrel in the section that can be inserted into the cap has a first locking element on the outside. The sealing cap in the corresponding section has interactive second locking elements on the inside. The sealing cap can thus be put onto barrel with little force and thus less cracking occurs. To facilitate locking, the cap has a large number of second locking elements that are arranged peripherally. In each case, an expansion section is provided in the wall of cap between each pair of adjacent locking elements.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: December 24, 2002
    Assignee: Schering Aktiengesellschaft
    Inventor: Norbert Witowski
  • Patent number: 6394985
    Abstract: A backflow proof structure for a syringe comprising a central cylinder portion and two blocks positioned in a protruding end of the syringe, on the bottom of the cylinder portion is a flared portion and on the top thereof is a tip, the outer space of the tip is filled with a piece of crystallized syrup to separate a crown cap covering the top of the tip from the cylinder portion; when the cylinder portion is placed in the protruding end, and a silicone cube is placed there-beneath, an irregular-shaped stopper is placed to closely contact the bottom of the protruding end to push the crown cap on the top of the cylinder portion out of the protruding end.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: May 28, 2002
    Assignee: Future Top Medical Environment Technic Co., Ltd.
    Inventor: Bih-Chern Lin
  • Patent number: 6383168
    Abstract: In accordance with an embodiment of the invention, a needleless injection apparatus includes a cartridge having a plunger disposed at a rearward end. The cartridge includes an inner portion with a throat at a forward portion and a displaceable outlet valve initially disposed within the cartridge throat. The cartridge further includes a generally outwardly facing surface and a system for selectively providing driving force to drive the plunger in a forward direction. The apparatus also includes a nozzle for receiving the cartridge, the nozzle defining a rearward, cartridge-receiving portion, and having a forward portion terminating in and defining a valve abutment surface with a plurality of channels and an injection orifice.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: May 7, 2002
    Assignee: Bioject Medical Technologies Inc.
    Inventors: Sergio Landau, James M. Bonicatto
  • Patent number: 6132395
    Abstract: A cartridge and nozzle assembly for use in a needless injection system is provided.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: October 17, 2000
    Assignee: Bioject, Inc.
    Inventors: Sergio Landau, James M. Bonicatto
  • Patent number: 6080461
    Abstract: Solid disks of polyethylene oxide are radiation crosslinked to instill viscoelastic memory. The disks are then pierced with a needle, heated, cooled and the needle removed to form disks containing a flow orifice in each which upon contact with water will revert to solid disks. A disk with a flow orifice made as just described when used as a memory flow control valve in a conventional injection device will produce a syringe with a single-use, auto-destruct capability. When the disk is inserted in a retainer in the flow channel of the injection device, a drug/vaccine can be drawn into the syringe and then expelled for a preselected time less than six minutes before the water in the drug/vaccine causes the flow orifice in the disk to close, the disk then reverting to its solid shape due to its viscoelastic memory.
    Type: Grant
    Filed: March 10, 1994
    Date of Patent: June 27, 2000
    Assignee: The Johns Hopkins University
    Inventors: John J. Wozniak, Michael C. Robertson
  • Patent number: 6068614
    Abstract: A plastic pre-filled syringe which includes an open ended barrel sealed at one end by a moveable stopper and sealed at the other end by a closure frangibly connected to the syringe. The syringe also includes an overcap which can be moved so to engage with the closure whereby removal of the overcap will cause the closure to be separated from the rest of the syringe and reveal the contents for injection.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: May 30, 2000
    Assignee: Astra Pharmaceuticals PTY, Ltd.
    Inventors: Michael Browning Kimber, Frank Alexander Popovsky
  • Patent number: 5908409
    Abstract: A device for forming a leakproof closure on the terminus of a tubing having an elastic wall. The device consists of a plug insertion tool and a plug. The plug is a elongate member having a convex distal end and a proximal end. The plug insertion tool has a handle portion which is dimensioned to be grasped by a user for manipulation. The distal end of the insertion tool has a rod projecting axially therefrom which is adapted to releasably engage the proximal end of the plug. The plug is dimensioned to fit snugly within the elastically distended lumen of the tubing. In operation, the plug insertion tool is releasably attached to the proximal end of the plug by engagement means such as mating threads and the distal end of the plug inserted into the open end of the tubing and advanced by means of the insertion tool. The intralumenal portion of the plug forms a leakproof seal with the elastic wall of the tubing.
    Type: Grant
    Filed: August 26, 1997
    Date of Patent: June 1, 1999
    Assignee: McGhan Medical Corporation
    Inventors: Jason D. Rinehart, David J. Schuessler
  • Patent number: 5643224
    Abstract: The invention relates to a safety valve plug to be used in pre-filled syringes, of the kind comprising a cylindrical hollow body into which a coaxial plunger is displaced, projecting outwardly from one of the bases; while a conical portion is defined at the opposite base, the conical portion receiving the injection needle and being called "plugging cone", the valve plug being snug fit inside said "plugging cone" with its end head bearing on the mouth thereof, said valve plug comprising a substantially cylindrical solid body having a conical end portion and the other portion, defining its head, being cylindrical and of a cross section larger than the rest of the body; the cylindrical body having, following said conical end, two faceted faces extending adjacent the head.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: July 1, 1997
    Inventors: Jaime Luis Szapiro, Leonardo Szames, Saul Moreno
  • Patent number: 5637100
    Abstract: An improved syringe is provided which can be used in any step of preparation of a medicament by vacuum freeze-drying, etc., storage of a medicament, mixing of medicaments and dosing of a medicament in a sanitary and stable manner. The syringe comprises a cylinder having a front end part at one end and an opening part at another end and a bypass running in the longitudinal direction near the central position of the cylinder on the inner wall within the cylinder. A first sealing stopper is adapted, at a position toward the opening part of the cylinder from the bypass within the cylinder, to form a first compartment between the front end of the cylinder and the first sealing stopper. A second sealing is stopper adapted, at a position toward the opening part of the cylinder from the first sealing stopper within the cylinder, to form a second compartment between the first sealing stopper and second sealing stopper.
    Type: Grant
    Filed: October 3, 1995
    Date of Patent: June 10, 1997
    Assignee: Daikyo Seiko, Ltd.
    Inventor: Morihiro Sudo
  • Patent number: 5558664
    Abstract: The device consists of: (a) an application reservoir or cell (1) whose base has a filling hole (4) for the solution and an opening that is fitted with a stopper (5) which presents micro-recesses on its periphery for administration of the solution on the skin; (b) a balloon (2) to pressurize and stabilize flow of the solution within the reservoir; and (c) a lid (3) to hermetically seal the aforesaid reservoir. The device is used in the form of a bracelet, abdominal belt or patch for application of solutions like trinitrine, oestradiols, etc. onto the skin.
    Type: Grant
    Filed: January 4, 1994
    Date of Patent: September 24, 1996
    Inventors: F. X. Sarzaud, Jean Perego, A. Cabrera
  • Patent number: 5531720
    Abstract: A kit for starting an I.V. is disclosed, as is a coupling for preventing blood and fluids from spilling out of the kit's catheter. The kit is comprised of a catheter portion, a coupling portion and a flesh piercing portion. The cannula portion includes a cannula having a hub. The coupling portion is comprised of first and second tubular portions, and a septum bound integrally therebetween. The flesh piercing portion is comprised of a needle and a handle. The method disclosed includes the steps of lodging the first tubular portion of a resilient coupling into the hub of a catheter; driving a guide needle axially through the coupling and catheter; driving the coupling and catheter into a vein; and withdrawing the guide needle from the catheter and coupling. Although blood flows into the catheter, it is prevented from flowing beyond the self-sealing septum.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: July 2, 1996
    Inventor: Stephen L. Atkins
  • Patent number: 5531255
    Abstract: A process and apparatus used in manufacturing prefilled, sterile delivery devices such as syringe assemblies. The process includes sealing a syringe container portion at both ends and filling the same through a port provided in the container portion between the two ends. After filling, the port is closed and sealed and the syringe assembly is sterilized to provide a sterile delivery device with sterile contents. A suitable syringe container portion for producing prefilled, sterile delivery devices is also disclosed.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: July 2, 1996
    Assignee: Mallinckrodt Medical, Inc.
    Inventor: Rita D. Vacca
  • Patent number: 5531710
    Abstract: A closure is provided for a syringe of the type having a housing with a substantially tubular and cylindrical neck with a through bore through which the contents of the syringe are dispensed. The closure includes an elongated probe having a free end and a cross-sectional area substantially the same as the syringe through bore. The closure further includes a first and second tubular and cylindrical sealing ring. The first tubular and cylindrical ring has an inner diameter substantially the same as the outer diameter of the syringe neck while the second sealing ring is positioned concentrically around the first sealing ring. The sealing rings and probe are dimensioned so that, upon insertion of a free end of the probe into the syringe through bore, the probe and first sealing ring sealingly engage both the internal and external surfaces of the syringe neck. Simultaneously, the free ends of the first and second sealing ring sealingly engage the outer surface of the syringe housing.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: July 2, 1996
    Assignee: Courtaulds Aerospace, Inc.
    Inventors: Nguyen T. Dang, Lawrence B. Martin, Richard Jerrard
  • Patent number: 5529189
    Abstract: A disposable single-use kit for administering a precise dose of radioactive tracer to a subject with an accuracy of at least 99.9% by weight. The kit comprises a syringe, pre-filled with a known quantity of a radioactive tracer as injectate. The back of a small-bore needle is affixed to the syringe front. The front of a removable plastic needle cover incorporates airtight means for creating and maintaining an airlock in the needle front, thereby to prevent any contact between the tracer and the cover and so preclude any loss of tracer upon removal of the cover from the needle. A valve normally seals the syringe back, the valve including actuatable means for enabling a fluid flow into the syringe back, both for pre-filling of the syringe with injectate and for flushing of the injectate from the syringe into the subject.
    Type: Grant
    Filed: August 2, 1995
    Date of Patent: June 25, 1996
    Assignee: Daxor Corporation
    Inventor: Joseph Feldschuh
  • Patent number: 5273542
    Abstract: The present invention is a hypodermic syringe pre-filled with a volume of a desired solution. A plug member is positioned within the hypodermic syringe in between the pre-filled fluid and the lumen of the syringe's cannula. The presence of the plug member within the hypodermic syringe separates the cannula from the pre-filled fluid thereby leaving the cannula unaffected by the presence of the fluid within the syringe. As the plunger of the hypodermic syringe is engaged, the pressure of the pre-filled fluid is increased. The fluid pressure acts upon the plug member, displacing the plug member when a predetermined fluid pressure is achieved. Once the plug member is displaced, the occlusion between the pre-filled fluid and the cannula is removed and the pre-filled fluid is free to flow through the lumen of the cannula.
    Type: Grant
    Filed: September 14, 1992
    Date of Patent: December 28, 1993
    Assignee: The Medtech Group, Inc.
    Inventor: Joseph W. Blake, III
  • Patent number: 5098410
    Abstract: An infusion catheter adapter and cap assembly, the catheter adapter has a housing with an input, an output and a side port, normal to the housing axis, which has a cap. The cap is fixedly attached to the housing by a living hinge with a retaining knob. The retaining knob on the living hinge conjugates with a groove on the housing. The groove is formed as a transverse channel defined by two opposing locking fingers. The position of the retaining knob in the groove is further ensured by a recess on the knob which conjugates with a peak in the groove to center and lock the retaining knob in the groove.
    Type: Grant
    Filed: December 13, 1989
    Date of Patent: March 24, 1992
    Assignee: Becton, Dickinson and Company
    Inventors: Walter L. Kerby, Rocky A. Revels, Kevin P. Woehr
  • Patent number: 5000735
    Abstract: A hyperdermic syringe having a plunger which separates from a piston inside a barrel of the syringe after a downward stroke of the plunger preventing reuse of the syringe. The plunger breaks breakaway portions mounted inside the piston when pushed downward to unload the syringe effectively separating the plunger from the piston and destroying the syringe, preventing the piston from being withdrawn for the purpose of reloading the syringe. In another embodiment, a connector is used to releasably engage a plunger to a piston. Downward movement of the plunger causes upward extensions of the connector to move toward each other and lock together. The plunger disengages from the connector and piston after the extension lock together. A modified tip portion of a barrel containing a valve ball and valve flaps may be used to prevent the syringe from being used after a single use discharging medicinal fluid from the syringe. The valve ball blocks flow of medicinal fluid into the syringe after use of the syringe.
    Type: Grant
    Filed: January 5, 1989
    Date of Patent: March 19, 1991
    Assignee: The Regents of the Univ. of California
    Inventor: James P. Whelan
  • Patent number: 4986278
    Abstract: A biopsy syringe for removing a specimen from a subject includes a tubular housing having a long hollow needle and two pistons. The first piston carries a mandrel received in the hollow needle. The second piston defines a chamber between it and the first piston enabling the syringe to be pre-loaded with a vacuum which is manually controllable so as to permit the first piston to be actuated to a retracted position in a smooth and simple manner while holding the biopsy syringe.
    Type: Grant
    Filed: December 18, 1989
    Date of Patent: January 22, 1991
    Inventors: Mordechai Ravid, Dan Kedem, Uzi Kedem
  • Patent number: 4961728
    Abstract: A syringe assembly includes a barrel having an inside surface describing a chamber for retaining fluid, an open proximal end and a distal barrel end having a passageway therethrough in fluid communication with the chamber. A plunger rod includes an elongate body portion, a proximal end and a distal end with a stopper at the distal end. The stopper is slidably positioned in fluid-tight engagement in the barrel. A locking element is positioned in the barrel between the plunger rod and the inside surface of the barrel. The locking element includes at least two proximally and outwardly facing non-parallel locking barbs, a distally and inwardly facing resisting edge and an inwardly facing driving edge. The driving edge is adaped to interact with the plunger rod to move the locking element along the barrel as the stopper is advanced distally along the barrel.
    Type: Grant
    Filed: December 30, 1988
    Date of Patent: October 9, 1990
    Assignee: Becton, Dickinson and Company
    Inventor: Anthony J. Kosinski
  • Patent number: 4952206
    Abstract: A single use syringe wherein the essential concept is to create a valve within the orifice that leads from the drug chamber into the chamber leading to the needle. The valve consists of a conical washer supported within the chamber by inclined barbs formed on its outer perimeter. The barbs will only allow the washer to move in one direction; toward an orifice at the needle end of the chamber. Initially the washer is positioned so that it does not impede fluid flow in either direction. Engaging the washer but not attached to it is an expansion plug. The expansion plug can absorb fluid and expand to force the washer against the opening leading to the needle, to thereby occlude fluid flow. The process is slow, taking at least several minutes, thereby permitting the syringe to be used once for its intended purpose before occlusion occurs.
    Type: Grant
    Filed: May 19, 1989
    Date of Patent: August 28, 1990
    Assignee: Anco Engineers, Inc.
    Inventors: Paul Ibanez, Frederick J. Gray
  • Patent number: 4941876
    Abstract: The device comprises a cylindrical ampoule which is closed at one end and opened at the other end. The ampoule has a relatively large circular cylindrical zone adjacent the closed end and a relatively small cylindrical zone disposed between the relatively large cylindrical zone and the open end of the ampoule. A piston valve engages the open end of the ampoule to provide sealing engagement and dispensing of the liquid contents when desired. An intermediary stopper engages the relatively small cylindrical zone, when the stopper is in a storage position, to divide the ampoule into first and second storage compartments. The stopper is shaped to provide tight sealing engagement with the relatively small circular cylindrical zone while providing at least one opening, between its lateral surface and the interior wall of the ampoule, for allowing passage and mixing the substances contained in the compartments, when it is positioned in the relatively large circular cylindrical zone.
    Type: Grant
    Filed: December 10, 1987
    Date of Patent: July 17, 1990
    Assignee: Medicorp Holding S.A.
    Inventors: Gabriel Meyer, Ernst Howald
  • Patent number: 4929230
    Abstract: A syringe for hypodermic injection wherein multiple pistons seal various number of chambers. One piston provides the basic operating force to dispell the contents from a chamber or successive chambers and another piston or other pistons forming a chamber or additional chambers permitting release of the chamber contents or successive chamber contents and a syringe holder for holding, using and disposing of the syringe minimizing potential of accidental sticking by the needle of the syringe.
    Type: Grant
    Filed: September 30, 1988
    Date of Patent: May 29, 1990
    Inventor: Frederick W. Pfleger
  • Patent number: 4832693
    Abstract: A single use hypodermic needle syringe is constructed in a manner which provides for the automatic self destruction of the fluid passage during the initial use upon the first complete injection stroke. Because the fluid passage is destroyed upon the first initial use of the hypodermic needle syringe, the syringe is rendered useless and must be discarded. Because the syringe is discarded after one use, the spread of infectious diseases will be inhibited.
    Type: Grant
    Filed: October 9, 1987
    Date of Patent: May 23, 1989
    Inventor: Walter W. Gloyer
  • Patent number: 4741737
    Abstract: A prefilled ampoule-syringe including an ampoule body having a smaller inner dimension than the body and a stopper means associated with an external capsule for closing the ampoule. The stopper is provided with an internal conduit having at least one transverse branch opening into a longitudinal branch between the interior of the capsule body and a needle-holding tip. The capsule is arranged for actual movement from a position within the neck where it is in a closed position to an open injection position within the ampoule body. When the capsule is in the position in the neck of the ampoule, the contents of the ampoule are in contact only with the walls of the ampoule and the inner surface of the stopper which faces into the neck. When the stopper is moved to injection position, the contents of the ampoule pass through the transverse passage and down the longitudinal passage to the needle holding tip for injection into a patient.
    Type: Grant
    Filed: October 2, 1986
    Date of Patent: May 3, 1988
    Assignee: Medicorp Holding S.A.
    Inventors: Gabriel Meyer, Ernst Howald
  • Patent number: 4613326
    Abstract: A two-component syringe assembly includes an elongate barrel having a chamber for retaining fluid and a distal end having a passageway therethrough communicating with the chamber. A bypass stopper is slidably positioned in fluid-tight engagement inside the barrel. The barrel also includes a bypass defining a bypass zone positioned along the barrel for allowing fluid to flow around the bypass stopper when the bypass stopper is positioned intermediate the ends of the barrel in the bypass zone. A stopper is slidably positioned in fluid-tight engagement inside the barrel. A rigid plunger rod having an elongate body portion engages the stopper to facilitate its operation. A barrier flange is positioned on the body portion and intermediate the ends thereof.
    Type: Grant
    Filed: July 12, 1985
    Date of Patent: September 23, 1986
    Assignee: Becton, Dickinson and Company
    Inventor: Joseph M. Szwarc
  • Patent number: 4479801
    Abstract: A device in the form of a syringe having a barrel with a cylindrical neck portion in the end thereof and a plunger axially displaceable therein, a hollow needle and a hub securing the hollow needle to the open end of the barrel with a chamber in between dimensioned to have a cross section greater than the cross section of the bore and a sealing disc within the neck of the barrel mounted for displacement between sealing position for separating the needle from the barrel and unsealing position enabling fluid to flow from the barrel through the chamber to the needle.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: October 30, 1984
    Inventor: Milton J. Cohen
  • Patent number: 4469482
    Abstract: The invention relates to a disposable syringe comprising a barrel in which a piston is provided and to which a needle is or can be connected to the front, a stopper being present in the barrel between piston and needle or needle connection means. The inner wall of the barrel is locally deformed between stopper and needle or needle connection so that at the area of the deformation injection liquid can reach the cannula past the stopper and during nurse-aspiration the stopper is held, in which body fluid can reach the part of the barrel present behind the stopper.
    Type: Grant
    Filed: July 26, 1982
    Date of Patent: September 4, 1984
    Assignee: Duphar International Research B.V.
    Inventors: Rokus C. D. Lissenburg, Paulus R. Kamstra
  • Patent number: 4460357
    Abstract: A device in the form of a syringe having a barrel with a cylindrical neck portion in the end thereof and a plunger axially displaceable therein, a hollow needle and a hub securing the hollow needle to the open end of the barrel with a chamber in between dimensioned to have a cross section greater than the cross section of the bore and a sealing disc within the neck of the barrel mounted for displacement between sealing position for separating the needle from the barrel and unsealing position enabling fluid to flow from the barrel through the chamber to the needle.
    Type: Grant
    Filed: June 25, 1982
    Date of Patent: July 17, 1984
    Inventor: Milton J. Cohen
  • Patent number: 4445896
    Abstract: A catheter plug for sealing the proximal end of a parenterally placed catheter and permitting repeated small volume injections and delivery of parenteral fluids without disturbing the sterility of the catheter. The catheter plug has a compression chamber for applying compression to a self-sealing elastometric septum thereby enhancing the septum's self-sealing characteristics. Compression force is applied to the septum by screw movement between oppositely threaded male and female couplers. The catheter plug is particularly useful in situations where pressures higher than arterial pressures are encountered or where it is desirable to leave the catheter indwelling for long periods of time.
    Type: Grant
    Filed: March 18, 1982
    Date of Patent: May 1, 1984
    Assignee: Cook, Inc.
    Inventor: Cesare Gianturco
  • Patent number: 4436098
    Abstract: A needle assembly preferably suitable for single sample blood collection and for determining vein entry when collecting a blood sample from a patient into a vacuum collection device. This assembly includes a housing with an interior chamber having a blood inlet needle on one side of the housing and a blood outlet needle on the other. The outlet needle extends interiorly into the chamber, is open at its distal end and includes a side hole therethrough. A vent plug covers the side hole by surrounding the outlet needle inside the chamber, while a sealant plug covers the open end of the outlet needle. This arrangement prevents liquid from flowing into the holes while allowing gas to flow through the vent plug into the side hole for escape from the assembly whereby the prevented liquid may then be viewed by a user through a transparent portion of the housing.
    Type: Grant
    Filed: March 16, 1981
    Date of Patent: March 13, 1984
    Assignee: Becton Dickinson Company
    Inventor: Joseph Kaufman