Abstract: An automatic injecting device including an elongated housing assembly, a stressed spring assembly mounted within the housing assembly so as to be released in response to a predetermined manual acutation procedure, and a medicament cartridge assembly mounted within the housing assembly in cooperating relation with the stressed spring assembly comprising a hypodermic needle and a medicament container housing forward and rearward individual dosages of different relatively incompatible liquid medicaments mounted therein and separated by a deformable stopper. The medicament container is formed of glass and includes a cylindrical wall open at its rearward end and having an exteriorly flanged necked down forward end portion. A hub assembly connects the exteriorly flanged necked down forward end portion with the hypodermic needle.

Abstract: A package for materials that are to be mixed just prior to use comprises a squeezable container into which is inserted a barrel containing a plunger. One substance to be mixed is placed within the container. The second substance is placed within a compartment formed within the barrel between a pair of pistons having flexible sealing rings. Telescoping of the plunger rod into the barrel causes the upper piston to advance into the compartment. The advancing upper piston exerts hydraulic pressure causing the lower sealing piston to detach from the barrel allowing internal mixing of the substances into a mixed fluid. By squeezing the container side wall, mixed fluid may be dispensed from a forward end of the plunger rod communicating with the container interior through a series of passageways.

Abstract: A two-component syringe includes a barrel having a chamber for retaining fluid and a distal end of the barrel having a passageway therethrough communicating with the chamber. A by-pass stopper is slidably positioned in fluid-tight engagement inside the barrel. The stopper has a distal rib contacting the barrel, a recess on the proximal side of the rib and a groove in the rib for allowing fluid communication between the recess and the chamber. This groove is positioned angularly with respect to the longitudinal access of the barrel so that liquid passing therethrough is directed angularly with respect to the longitudinal axis of the barrel. The barrel also includes a raised peripheral portion serving as a by-pass and defining a by-pass zone. The by-pass zone is shorter than the length of the stopper along the longitudinal axis of the barrel.

Abstract: A sequential medication delivery device for intravenous administration of plural medications is disclosed. A secondary medication can be administered to a patient followed by an automatic resumption of the delivery of the primary medication at a predetermined flow rate. The disclosed medication delivery device includes an internal valving system and an associated medication chamber that contains the secondary medication to be delivered. While the medication chamber contains such secondary medication, the flow of primary medication to the patient is interrupted. However, once the medication chamber has been substantially emptied the flow of primary medication to the patient is resumed automatically.

Abstract: The invention relates to a syringe for injecting two or more injection liquids which may not be in contact with each other for a longer period of time, comprising a barrel having a piston, a needle on the front side of the barrel, a sealing stopper in the barrel on the front, and one or more separating stoppers which, before use of the syringe, keep the injection liquids separated from each other. The needle is connected to the front of the barrel by means of a needle holder comprising a collar to connect the needle holder to the barrel, an neck to connect the injection needle, and a hollow shaft between collar and neck, in which a passage is formed in the inner wall of the shaft and the rear face of the neck, past which passage the injection liquids can reach the cannula when during use of the syringe the stoppers are moved into the shaft of the needle holder.

Abstract: In a combined large and small bore syringe, the small bore syringe is used as the plunger for the large bore syringe. Movement of the small bore syringe plunger produces a high pressure, low volume flow while subsequent movement of the entirety of the small bore syringe as the plunger of the large bore syringe produces a low pressure, high volume liquid flow.

Abstract: In a seal for two compartment mixing syringe having an outer barrel with an inner barrel partially disposed therein, and a seal on the dispensing end of the inner barrel, and a plunger disposed in the inner barrel, the improvement is wherein the seal is a combination of an aperture in the dispensing end of the inner barrel and a plug disposed in the aperture. The plug has a cylindrical portion of resilient and compressible material adapted to be compressibly disposed in the aperture but displaceable from the aperture by fluid pressure exerted by movement of the plunger in the inner barrel. A reduced diameter portion of the plug provides a fluid pathway between the inner barrel and the outer barrel when the cylindrical portion is displaced from the aperture by such fluid pressure. An increased diameter portion prevents the plug from passing through the aperture and into the outer barrel.

Abstract: A syringe for delivering two separated bodies of fluid comprising: a first piston for separating the two bodies of fluid; a second piston for pushing the two bodies of fluid out of the syringe; and a fluid chamber having a no-pass zone in which the pistons can slide and which has a cross section that each of the pistons substantially fills, preventing the passing of fluid around the pistons when they are in the no-pass zone, an output zone to direct fluid pushed out of the syringe by the pistons, and a bypass zone, for receiving the first piston, which connects the no-pass and output zones and which has a cross section that the first piston is unable to fill, so that when the first piston enters the bypass zone the fluid between the first and second pistons can pass around the first piston to the output zone.

Abstract: A self-displacing separator disc is positioned transversely of a tubular member to form a seal in the bore of the member, which may be a hypodermic syringe, to provide two or more separate chambers containing material which is to be kept separated until use thereof. The separator disc is constructed to respond differentially to force or pressure on one side thereof by having peripheral regions of different frictional response with respect to the bore wall such that the disc is displaced out of a transverse orientation upon exposure to force or pressure. Various different structures of discs are described to achieve self-displacement of the disc in a bore which preferably has a uniform internal diameter along its effective length.

Abstract: In a syringe assembly comprising an outer barrel for a powder medicament, an inner barrel telescopically mounted in the outer barrel for diluent, seal means isolating the powder and diluent compartments comprising a plug member made of a resilient material sealingly engaging in the discharge opening of the inner barrel, plunger means mounted on the discharge end of the inner barrel including a hollow plug chamber closed at one end remote from the discharge end of the inner barrel by a wall having a plurality of discharge openings therein, said plug adapted upon pressure buildup in the inner barrel to be displaced axially outwardly into said plug chamber to permit flow of diluent from the inner barrel to the powder compartment.

Abstract: An automatic injector comprising an elongated housing assembly having a forward end, a stressed spring assembly mounted within the rearward end of the housing assembly so as to be released in response to a predetermined manual actuation procedure, and a medicament injection cartridge assembly mounted within the forward end of the housing assembly in cooperating relation with the stressed spring assembly. The improvement of the present invention is in the medicament injection cartridge assembly which includes a medicament container, a hypodermic needle disposed forwardly of the container mounted in a sterile condition within the housing assembly adjacent the forward end thereof. A forward seal is provided for sealing the forward end of the container from the hypodermic needle. A rearward piston is mounted in the rearward end of the container for forward movement therein in slidably sealed relation thereto.