Thermal Applicators Patents (Class 607/96)
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Patent number: 8986359Abstract: A multi-zone electric heating blanket. The blanket may be shaped to cover the outstretched arms or other body parts of a patient. The blanket includes first and second body part portions and a connecting bridge. The interconnection via the bridge leaves an open gap between the first and second body part portions for unblocked access to the patient. A power controller may supply power to heating elements in both body part portions based on a temperature sensor in one of the body part portions.Type: GrantFiled: October 10, 2008Date of Patent: March 24, 2015Assignee: Augustine Temperature Management LLCInventors: Scott D. Augustine, Ryan S. Augustine, Randall C. Arnold, Keith J. Leland, Joshua P. Waldman, Rudolf A. Deibel, Thomas F. Neils
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Publication number: 20150080989Abstract: A method (100) of moulding an article comprises: forming (104) a first portion (2) of the article by injecting a first material (50) into a first mould (61), the first mould being shaped so as to define a flange (8) on the first portion of the article; placing (106) the first portion of the article into a second mould (91), the second mould having a first plate (90) and a second plate (92); compressing (108) the flange between the first and second plates of the second mould; and forming (110) a second portion (4) of the article by injecting a second material (55) into the second mould whilst the flange is compressed between the first and second plates of the second mould.Type: ApplicationFiled: March 22, 2013Publication date: March 19, 2015Inventor: Louise Mohn
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Publication number: 20150080769Abstract: The invention relates to an applicator for use with a device for treating subcutaneous lipid-rich cells by cold treatment, wherein the applicator (1) comprises a contact surface (2) that is formed as a surface (3) of a solid treatment plate (4) made of aluminum or another material having good heat conductivity. The invention further relates to a device for treating subcutaneous, lipid-rich cells by cold treatment comprising a heat transfer circuit and an applicator (1) through which a heat transfer medium (6) flows for treating a live body. The device consists of a refrigeration device (30) for providing the heat transfer medium (6) having a specific temperature and connecting supply lines (29) to the applicator as well as a compensator (31) that compensates the weight of the applicator.Type: ApplicationFiled: March 7, 2013Publication date: March 19, 2015Inventor: Friedemann LOTSCH
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Patent number: 8979777Abstract: Apparatus for a disposable, portable thermal therapy device that is self-contained for shipping as a single unit to a patient. The therapy device has a shipping configuration that presents a single, self-contained durable container. The container includes an insert that defines a compartment between the insert and the container. The compartment stores various electrical components, such as the power connection. The insert has a cavity that contains a pump and stores a thermal pad and associated fluid lines. The insert is a shell with a cable grip that secures the cable from pump and a recessed area for securing the pump. The edges of the insert are sealed to the inside surface of the box. A carrying strap is secured to the sidewalls of the box in a manner that prevents protrusions and aid in minimizing storage.Type: GrantFiled: October 24, 2011Date of Patent: March 17, 2015Assignee: Adroit Medical Systems, Inc.Inventor: Scott Gammons
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Publication number: 20150073514Abstract: Endovascular catheters and control wires for operating the catheters and associated systems, apparatuses, and methods are disclosed include a catheter apparatus having an elongated shaft, a therapeutic assembly at a distal portion of the shaft, and a handle at a proximal portion of the shaft. An actuator is located at the handle and operably coupled to the therapeutic assembly via a tuned control member extending through the shaft. The tuned control member includes a control wire and a tuning component attached to one another within the shaft. The tuned control member is configured to achieve a desired tuned force-displacement response by modifying the stress-strain response that a non-tuned control wire would ordinarily provide without the intervening tuning component.Type: ApplicationFiled: September 10, 2013Publication date: March 12, 2015Applicant: Medtronic Ardian Luxembourg S.a.r.I.Inventors: Vincent Ku, Andrew Wu
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Publication number: 20150073516Abstract: The present invention provides a low-cost, low-power therapeutic hypothermia device for use in developing nations. The device includes a first and second receptacle separated by a space filled with a porous material such as sand. A cooling chemical can also be added to the porous material in order to speed cooling. Water is added to the porous material and a neonate is placed into the device for therapeutic hypothermia treatment. The neonate is monitored carefully using temperature sensors and a feedback system integrated into the device. Cooling can be modulated and/or warming commenced by adding Styrofoam blocks to raise the neonate off the surface of the device.Type: ApplicationFiled: April 9, 2013Publication date: March 12, 2015Applicant: THE JOHNS HOPKINS UNIVERSITYInventors: Soumyadipta Acharya, Robert Allen, Winston J. Aw, Samrie Beshah, Michael V. Johnston, John J. Kim, Robert Kim, Ryan Wai Yan Lee, Erika M. Moore, Neil P. O'Donnell, Youseph Yazdi, Simon Ammanuel, Nathan Buchbinder
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Publication number: 20150065921Abstract: A medical apparatus (300, 400, 500, 600, 700) comprises a heating system (304) for heating a target zone (324) of a subject (320), wherein the energy density in a predefined volume is modeled (338) using a thermal model and a processor (330) for controlling (340) the heating system (304).Type: ApplicationFiled: March 22, 2013Publication date: March 5, 2015Inventors: Julia Kristina Enholm, Kirsi Ilona Nurmilaukas, Max Köhler
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Publication number: 20150066119Abstract: Infant warming systems are described herein generally comprising a temperature regulation assembly which encloses a phase change material (PCM). The temperature regulation assembly may be initially heated (or re-heated) by water contained within a heating assembly and then placed within a retaining pouch of an infant bedding. The PCM may then provide constant heat over a period of time to the infant. A control/indicator interface coupled to the regulation assembly may constantly monitor the temperature of the PCM as well as the ambient temperature to provide one or more indications or alerts to the user with respect to one of several states of the warming assembly.Type: ApplicationFiled: August 29, 2013Publication date: March 5, 2015Applicant: Embrace InnovationsInventors: Rahul A. PANICKER, Eu-wen DING, Srishti SUNDRAM, Satyan RAJ, Honey BAJAJ, Jane CHEN, Naganand MURTY, Linus LIANG
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Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
Patent number: 8968377Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.Type: GrantFiled: May 9, 2011Date of Patent: March 3, 2015Assignee: The Invention Science Fund I, LLCInventors: Edward S. Boyden, Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Eric C. Leuthardt, Stephen L. Malaska, Elizabeth A. Sweeney, Lowell L. Wood, Jr. -
Patent number: 8966981Abstract: A switched resonant power amplifier system for ultrasonic transducers is disclosed. The system includes an amplifier that receives and processes a driver output signal for generating a drive signal that is provided to an ultrasonic device for controlling output of the ultrasonic device. An output control circuit receives and processes a signal related to a feedback signal generated by the ultrasonic device and a divider reference signal, and generates a compensated clock signal that is adjusted for at least one of phase and frequency differences between the received feedback signal and the divider reference signal. A compensated drive circuit receives and processes the compensated clock signal for generating the divider reference signal, and for generating the driver output signal.Type: GrantFiled: July 16, 2013Date of Patent: March 3, 2015Assignee: Covidien AGInventors: James H. Orszulak, James W. McPherson
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Patent number: 8945113Abstract: An electrosurgical system includes an electrosurgical device, one or more temperature sensors associated with the electrosurgical device, a fluid-flow path leading to the electrosurgical device, and a flow-control device disposed in fluid communication with the fluid-flow path. The electrosurgical device includes a probe for directing energy to tissue. The electrosurgical system includes circuitry for detecting bending of the probe. The circuitry alerts the user of excessive bending by activating an alarm, such as an audible alarm, lighting one or more LEDs or other light sources, tactile feedback, or any other means. The electrosurgical system further includes a processor unit communicatively-coupled to the one or more temperature sensors and communicatively-coupled to the flow-control device. The processor unit is configured to control the flow-control device based on determination of a desired fluid-flow rate using one or more electrical signals outputted from the one or more temperature sensors.Type: GrantFiled: April 5, 2012Date of Patent: February 3, 2015Assignee: Covidien LPInventors: Joseph D. Brannan, Richard A. Willyard
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Patent number: 8944071Abstract: Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung are disclosed. The damaging of lung cells, damaging tissue, causing trauma, and/or destroying smooth muscle tone with the apparatus may be accomplished via any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.Type: GrantFiled: August 20, 2012Date of Patent: February 3, 2015Assignee: Asthmatx, Inc.Inventors: Bryan Loomas, Michael D. Laufer, David P. Thompson
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Patent number: 8945027Abstract: A calf garment assembly having, a calf garment having an internal chamber and being substantially airtight and being in fluid communication with a pressurized air source, and a heating element working in conjunction with the calf garment to provide heated DVT therapy.Type: GrantFiled: July 21, 2011Date of Patent: February 3, 2015Inventors: Munish K. Batra, Ronald J. Koch
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Patent number: 8945101Abstract: An apparatus and a method are provided for treating a targeted area of ocular tissue in a tissue-sparing manner comprising use of two or more therapeutic modalities, including thermal radiation source (such as an CW infrared fiber laser), operative in a wavelength range that has a high absorption in water, and photochemical collagen cross-linking (CXL), together with one or more specific system improvements, such as peri-operative feedback measurements for tailoring of the therapeutic modalities, an ocular tissue surface thermal control/cooling mechanism and a source of deuterated water/riboflavin solution in a delivery system targeting ocular tissue in the presence of the ultraviolet radiation. Additional methods of rapid cross-linking (RXL), are provided that further enables cross-linking (CXL) therapy to be combined with thermal therapy.Type: GrantFiled: May 2, 2011Date of Patent: February 3, 2015Assignee: Seros Medical, LLCInventors: Satish V. Herekar, Edward E. Manche, Donald J. Eaton
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Publication number: 20150032192Abstract: A heat treatment device with a handle portion, a tip portion, a power source, and a heating element. The tip portion is heatable to a desired temperature and can be positioned against an affected area for therapeutic treatment. The device can also have control circuitry that can adjust a current flowing to the heating element to regulate the treatment temperature.Type: ApplicationFiled: April 17, 2012Publication date: January 29, 2015Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLCInventor: Kevin Anthony Pezzi
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Patent number: 8940035Abstract: A method, device, and system for treatment of urinary tract disorders is provided. The device includes a catheter having multiple lumens for insertion into a urinary bladder and for providing fluid flow within the bladder and within the fluid reservoir within the urethra. The device further includes an anchor to be placed within the bladder. A port hub having multiple ports is connected at a proximal end of the catheter. A method of treatment includes providing heated fluid to a urinary bladder and to a fluid reservoir for insertion into an adjacent organ such as the urethra. Simultaneous treatment or separate treatment may be done. Optionally, a medicated solution may be added to the heated fluid. Additionally, pressure may be adjusted so as to optimize the therapeutic effect.Type: GrantFiled: November 3, 2010Date of Patent: January 27, 2015Assignee: Elmedical Ltd.Inventor: Uzi Eshel
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Publication number: 20150025421Abstract: The invention generally relates to methods for guiding physical therapy to a subject. In certain embodiments, methods of the invention involve providing stimulation to a subject's central nervous system to modulate one or more signals sent to or from a plurality of target regions of the subject. Methods of the invention further involve assessing the response of the plurality of target regions to the stimulation to determine if there is a differential response among the target regions to the stimulation, and providing focused physical therapy to at least one of the target regions based on the assessment of the response of the plurality of peripheral target regions to the stimulation.Type: ApplicationFiled: July 18, 2014Publication date: January 22, 2015Inventors: Timothy Andrew Wagner, Laura Dipietro, Uri Tzvi Eden
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Patent number: 8936631Abstract: A method of performing therapy on tissue using a medical apparatus. The apparatus includes a shaft configured for insertion into a hollow anatomical structure (HAS) and has a tissue sensor and a therapeutic energy application device both located on the shaft. The method comprises: receiving electrical power at a first power level and directing the first-level power to the tissue sensor and not to the therapeutic energy application device, thereby enabling tissue sensing with the tissue sensor; receiving electrical power at a second power level higher than the first-level power; and, in response to receipt of the second-level power, directing the second-level power to the therapeutic energy application device, thereby enabling performance of therapy on the tissue with the therapeutic energy application device. Additional methods and apparatus are disclosed as well.Type: GrantFiled: August 20, 2010Date of Patent: January 20, 2015Assignee: Covidien LPInventors: Hoa D. Nguyen, Arthur W. Zikorus, Stephen W. Lee
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Patent number: 8926677Abstract: An interstitial laser energy treatment apparatus having co-acting movable probe holders which facilitate positioning of a laser probe and thermal probe in different positions relative to a tissue mass such as the tumor to be treated and relative to each other to facilitate treating tissue masses based on the exact position, size and shape of the tissue mass.Type: GrantFiled: August 15, 2013Date of Patent: January 6, 2015Assignee: Novian Health, Inc.Inventors: Anthony J. Tomasello, William Graveman, Kambiz Dowlatshahi, Henry R. Appelbaum
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Patent number: 8929979Abstract: An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.Type: GrantFiled: June 18, 2007Date of Patent: January 6, 2015Assignee: Highland Instruments, Inc.Inventors: Timothy Andrew Wagner, Uri Tzvi Eden
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Publication number: 20150005614Abstract: Systems and methods are disclosed for treating back pain associated with a vertebral body of a patient. The system may include an external energy source configured to be positioned at a location external to the body of the patient, a linear configured to drive translation of the external source in one or more axes, a computer coupled to the external source and linear drive and programming executable on said computer for determining a target treatment site within or near the vertebral body based on acquired imaging data, positioning a focal point of the external energy source to substantially coincide with the target treatment site, and delivering a treatment dose of therapeutic energy at said target treatment site, wherein the treatment dose is configured to modulate a nerve within or near the vertebral body.Type: ApplicationFiled: December 21, 2012Publication date: January 1, 2015Inventors: Michael H. Heggeness, Richard C. Pellegrino, Rex Peters
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Publication number: 20140378740Abstract: An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.Type: ApplicationFiled: September 8, 2014Publication date: December 25, 2014Inventors: Timothy Andrew Wagner, Uri Tzvi Eden
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Patent number: 8915949Abstract: An ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An ultrasound emitter or transducer is delivered to a location within the body associated with the joint and heats the target region of tissue associated with the joint from the location. Such locations for ultrasound transducer placement may include for example in or around the intervertebral discs, or the bony structures such as vertebral bodies or posterior vertebral elements such as facet joints. Various modes of operation provide for selective, controlled heating at different temperature ranges to provide different intended results in the target tissue, which ranges are significantly affected by pre-stressed tissues such as in-vivo intervertebral discs. In particular, treatments above 70 degrees C., and in particular 75 degrees C.Type: GrantFiled: May 17, 2010Date of Patent: December 23, 2014Assignee: The Regents of the University of CaliforniaInventors: Chris J. Diederich, Jeffrey C. Lotz, Will Nau, David S. Bradford
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Patent number: 8911486Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue). In some embodiments, tissue can be cooled or heated by implanting a malleable or deformable thermal device in proximity to the targeted tissue. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner. The thermal device can be connectionless or can include penetrable regions, pre-attached tubing, or detachable connectors to facilitate application of cooling or heating means to the device. Methods are disclosed for utilizing thermal devices and for carrying out various treatment regimens that involve cooling or heating tissue using such devices.Type: GrantFiled: May 13, 2014Date of Patent: December 16, 2014Assignee: Neuraxis, LLCInventors: Michael Drnek, Dan Farley, John Sullivan
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Publication number: 20140364925Abstract: A modular shoulder cooling system. A retention panel is affixed over the shoulder. The retention panel is hald in position by a pair of straps attached to a belt around the user's waist. At least a portion of the inward facing surface of the retention panel is covered in loop material. Bags containing cooling medium are furnished. These are referred to as “cold packs.” Each cold pack has a first side with a soft, tactilly pleasing surface. This first surface is intended to face the user. Each cold pack also has a second side intented to face the inward facing surface of the retention panel. This second side includes one or more hook panels configured to engage the loop material on the inward facing surface of the retention panel. The user can attach a cold pack or packs to the rentention panel by pressing the hook panels on each cold pack against the loop material on the retention panel. Thus, no pockets are required.Type: ApplicationFiled: May 1, 2013Publication date: December 11, 2014Inventor: Bryan E. Kilbey
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Patent number: 8905036Abstract: The invention concerns an assembly for heat treatment of a region of a biological tissue (410) comprising energy-generating means (100) to supply energy to the region; means (200) for measuring and recording spatial temperature distribution in said region; a control unit (300) comprising means for point-to-point digital processing of the temperature distribution in the region. The invention is characterised in that the energy-generating means comprise means(110) for spatial and temporal distribution of the power available to them on said region, the control unit (300) comprising means (330, 350), based on the temperature distribution, for controlling the amount and distribution of energy supplied by the generating means (100).Type: GrantFiled: July 1, 2010Date of Patent: December 9, 2014Assignee: Koninklijke Philips N.V.Inventors: Chrétien Moonen, Bruno Quesson, Frédéric Vimeux
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Patent number: 8906009Abstract: Apparatus and methods for delivering electromagnetic energy to a patient's tissue with a reduction in the pain experienced by the patient. The tissue treatment apparatus includes a delivery device configured to transfer electromagnetic energy through the skin surface to a region of tissue and a vibration device mechanically coupled with the delivery device. The vibration device is configured to transfer mechanical vibrations through the skin surface to the region of tissue.Type: GrantFiled: July 12, 2013Date of Patent: December 9, 2014Assignee: Solta Medical, Inc.Inventors: Dragan D. Nebrigic, Herb Lara, Richard Hatch, Igor Leonidovich Tchertkov, Kai Nakamura, Laura England, Marlo Cinco
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Publication number: 20140357934Abstract: The present invention generally relates to systems and methods for changing tissue impedance in a region of a biologically generated field. In certain embodiments, the invention provides methods for changing tissue impedance in a region of a biologically generated field that involve applying focused energy to a region of charged particles in a region of tissue that includes a biologically based field, whereby the energy provided to the region of charged particles results in an impedance change to the region of tissue.Type: ApplicationFiled: May 9, 2014Publication date: December 4, 2014Applicant: Highland Instruments, Inc.Inventor: Timothy Andrew Wagner
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Publication number: 20140358204Abstract: A device and method for non-invasive treatment of menopausal hot flashes. The device includes a hand-held assembly sized to be held in the palm of a user's hand; a cooling plate within the assembly and a cradle which docks with the assembly. The cradle plugs into an AC power source and includes a Peltier-effect element for cooling a contact plate. The contact plate in the cradle abuts the cooling plate in the docked assembly and cools the same, keeping it at the lowered temperature and ready for immediate use. The cradle includes a heat sink for dissipating heat generated by the Peltier-effect element. The assembly is undocked from the cradle. The cooled plate is placed against the skin on the back of the neck and is moved back and forth to stimulate cold thermoreceptors in the skin, thereby counteracting the false trigger which caused the hot flash.Type: ApplicationFiled: May 31, 2013Publication date: December 4, 2014Inventor: Robert G. Dickie
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Publication number: 20140350645Abstract: The present application relates to systems and methods for altering temperature in a mammalian body. Optionally, the systems and methods can be used to lower or raise core body temperature of a mammalian subject. Optionally, the systems and methods can be used to lower or raise the temperature of glabrous skin of a mammalian subject.Type: ApplicationFiled: December 30, 2013Publication date: November 27, 2014Applicant: Board of Regents, The University of Texas SystemInventors: Kenneth R. Diller, Daniel W. Hensley, Timothy T. Diller
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Patent number: 8894644Abstract: A method and device for treatment of living cells with cold atmospheric pressure plasma while simultaneously applying selective electroporation of the cells are provided. The method is useful for the local selective killing of cancer cells, improvement of wound treatment and sterilization or decontamination of objects.Type: GrantFiled: August 12, 2010Date of Patent: November 25, 2014Assignee: INP Greifswald Leibniz-Inst fuer PlasmaforschungInventors: Manfred Stieber, Klaus-Dieter Weltmann, Thomas Von Woedtke, Christian Wilke, Uwe Ehrenberg
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Patent number: 8886304Abstract: An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.Type: GrantFiled: June 13, 2011Date of Patent: November 11, 2014Assignee: Highland Instruments, Inc.Inventors: Timothy A. Wagner, Uri T. Eden
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Patent number: 8882755Abstract: A novel medical probe assembly, system, and methods for the use thereof to treat tissue are described. The system optionally comprises an energy source, two probe assemblies, and one or more cooling devices to provide cooling to at least one of the probe assemblies. The probe assemblies may be configured in a bipolar mode, whereby current flows preferentially between the probe assemblies. The probe assemblies and system described herein are particularly useful to deliver radio frequency energy to a patient's body. RF energy delivery may be used for various applications, including the treatment of pain, tumor ablation and cardiac ablation.Type: GrantFiled: April 14, 2005Date of Patent: November 11, 2014Assignee: Kimberly-Clark Inc.Inventors: Mark Leung, Krishan Shah, Laura Conquergood, Subashini Chandran
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Patent number: 8882753Abstract: The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.Type: GrantFiled: October 10, 2008Date of Patent: November 11, 2014Assignee: Syneron Medical LtdInventors: Bankim H. Mehta, Scott A. McGill
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Patent number: 8882764Abstract: A method and apparatus for treating an intraosseous nerve. The method includes positioning a hollow shaft through the cortical shell of a vertebral body and into a cancellous bone region of the vertebral body. The hollow shaft includes an annular wall having a longitudinal bore therein, a proximal portion and a distal portion, and a first window extending transversely through the annular wall. An electrosurgical probe is advanced within the longitudinal bore from the proximal portion toward the distal portion. The electrosurgical probe includes a first treatment element at a distal end of the probe, wherein the first treatment element being in electrical connection with a power supply. The first treatment element is slidably disposed within the longitudinal bore so that the first treatment element is advanced radially outward from the window and shaft to affect treatment of the intraosseous nerve within the cancellous bone region.Type: GrantFiled: October 19, 2012Date of Patent: November 11, 2014Assignee: Relievant Medsystems, Inc.Inventors: Jeffrey K. Sutton, Thomas Ryan, Samit Patel, Richard Pellegrino
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Patent number: 8876819Abstract: A magnetically-guided catheter 100 includes a tip positioning magnet in the distal electrode assembly configured to interact with externally applied magnetic fields for magnetically-guided movement. A magnetically-guided mapping catheter 100 includes an electrically-conductive capsule in the form of a casing 146 that includes a distal ablation surface and isolates the positioning magnet from bio-fluids to prevent corrosion. An open irrigation ablation catheter includes an isolated manifold that isolates the positioning magnet from contact with irrigation fluid to prevent corrosion.Type: GrantFiled: June 15, 2011Date of Patent: November 4, 2014Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.Inventors: Troy T. Tegg, James V. Kauphusman
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Patent number: 8876875Abstract: The present invention is a two-layer garment adapted to receive one or more body parts to provide a user with compression and thermal therapy. The two layers comprise of an inner base layer having a compression fit and an outer mesh layer. The layers are attached to one another such that an intermediate space exists between the two layers. The intermediate space is accessible through one or more openings to the intermediate space. The opening and intermediate space are adapted to receive a thermal transferring element. A thermal pouch having a plurality of projections on an outward facing surface may receive the thermal transferring element prior to insertion into the intermediate space or the projections may be located on the thermal transferring element itself. The outer mesh layer receives the projections securing the thermal transferring element at any location, resulting in unmatched customizable thermal and compression therapy.Type: GrantFiled: February 21, 2014Date of Patent: November 4, 2014Assignee: Snapbac, LLCInventors: Ali Nilforushan, Kevin Bello
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Publication number: 20140315893Abstract: The invention provides 1,4-dihydropyridine derivatives of formula (I) wherein R1 is optionally substituted C6-24aryl group or 5 to 6 membered heteroaryl group comprising 1 to 3 nitrogen atoms or other heteroatoms like oxygen and sulphur, and combinations thereof; R2 and R3 are independently hydrogen or C1-6alkyl group; R4 and R5 are independently hydrogen, C1-6alkyl group optionally substituted with amino, mono- or di(C1-6alkyl)amino, or with 5 to 24 membered optionally fused heterocyclic ring attached by nitrogen and optionally comprising additional 1 to 3 N, O, S heteroatoms and optionally substituted with C1-6alkyl group or C1-6 alkoxy group; R6 is C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-6alkyl or arylC1-6alkyl group; and stereoisomers including enantiomers, diastereomers, racemic mixtures, mixture of enantiomers and combination thereof, as well as polymorphs, pharmaceutically acceptable salts, solvates, esters and prodrugs thereof for use in the therapeutic or prophylactic treatment of a disorder mediType: ApplicationFiled: November 22, 2012Publication date: October 23, 2014Inventors: Ferenc Fülöp, László Vígh, Zsolt Török, Botond Penke, Ibolya Horváth, Gábor Balogh, Sándor Bernáth, Ákos Hunya
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Publication number: 20140316218Abstract: Systems and methods for monitoring and/or controlling a brain state of a subject are provided. In certain embodiments, the method includes acquiring physiological data from sensors including electrophysiological sensors and optical sensors, assembling, using data from the electrophysiological sensors, a time-series signal indicative of a brain activity of the subject, and identifying, using the time-series signal, a burst suppression state described by a burst suppression period and a burst period. The method also includes computing, using data from the optical sensors, parameters associated with the burst suppression state, the parameters indicative of least one of a metabolic process and a hemodynamic process, and estimating, using the parameters, time-series signal, and burst period, a response function describing a time course of the parameters correlated with a burst during the burst suppression period.Type: ApplicationFiled: April 23, 2014Publication date: October 23, 2014Inventors: Patrick L. Purdon, Emery N. Brown, ShiNung Ching, David A. Boas, Maria Angela Franceschini, Jason Sutin
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Publication number: 20140305435Abstract: Disclosed herein is a system including a patient support unit having an enclosed patient environment, a heating module, a skin temperature sensor module, an environmental sensor module and a control system. The control system is configured to selectively operate the system in a pre-programmed weaning mode configured to gradually wean the patient from the warmed patient environment according to a series of stepped air temperature decreases performed over a series of stepped time durations to achieve a goal air temperature while maintaining a goal skin temperature within a weaning abort deviation. Related apparatus, systems, methods and/or articles are described.Type: ApplicationFiled: December 13, 2011Publication date: October 16, 2014Applicants: Drager Medical GmbH, Draeger Medical Systems, Inc.Inventors: Ulf Timme, Harald Kneuer, Philip Moehring
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Publication number: 20140303696Abstract: Cosmetic method and apparatus are provided that can provide cooling and/or freezing of skin tissue proximal to the skin surface to generate an appearance of lightening or reduced pigmentation in the skin. The skin can be cooled to a temperature of less than about ?5 degrees Celsius for a duration of about one minute or less, using a cooled surface that is at least 3 cm in width. A cooling arrangement can be provided to provide controlled heat removal from the skin tissue being treated. A sensor can optionally be provided to detect freezing of tissue proximal to the cooled surface.Type: ApplicationFiled: November 16, 2012Publication date: October 9, 2014Applicant: The General Hospital CorporationInventors: Richard Rox Anderson, Dieter Manstein, Henry HL Chan, Joseph Ting
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Publication number: 20140302154Abstract: Embodiments herein relate to the production of biocompatible magnetic nanoparticles with a high SAR-value which produce a large amount of heat when exposed to an alternating magnetic field. The produced heat can be used among others for therapeutic purposes, in particular for combating cancer.Type: ApplicationFiled: May 15, 2014Publication date: October 9, 2014Applicant: MagForce AGInventors: Norbert WALDOEFNER, Kerstin STIEF
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Publication number: 20140303697Abstract: Cosmetic method and apparatus are provided that can provide cooling and/or freezing of skin tissue proximal to the skin surface to generate an appearance of lightening or reduced pigmentation in the skin. The skin can be cooled to a temperature of less than about ?5 degrees Celsius for a duration of about one minute or less, using a plurality of cooled contact surfaces, each having a width between about 2 mm and about 20 mm. A cooling arrangement can be provided to provide controlled heat removal from the skin tissue being treated. A sensor can optionally be provided to detect freezing of tissue proximal to the cooled surfaces.Type: ApplicationFiled: November 16, 2012Publication date: October 9, 2014Applicant: The General Hospital CorporationInventors: Richard Rox Anderson, Dieter Manstein, Henry HL Chan, Joseph Ting
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Publication number: 20140303701Abstract: The Low Temperature Hyperthermia System illuminates nano-particles, which are implanted in a living organism at the locus of the cancer or into the cancer cells, with a precisely determined energy field. This energy field ensures that the optimal cancer cell and cancer stem cell destruction temperature of 42° C. is not exceeded in the tissue, which minimizes the release of Heat Shock Proteins and cancer stem cells. The Low Temperature Hyperthermia System uses specially designed nano-particles that exhibit a specific temperature rise in a given illumination energy field and then have no further temperature rise even if the applied illumination energy field increases beyond the optimal level. Alternatively, the nano-particles exhibit a tightly controlled temperature rise based on a pre-determined illumination energy field strength. This innovative approach can also use radiation and/or chemotherapy in conjunction with the nano-particle illumination to kill the majority of the cancer cells.Type: ApplicationFiled: June 19, 2014Publication date: October 9, 2014Inventors: Daniel B. McKenna, Robert J. Tondu
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Publication number: 20140303694Abstract: Described herein is a system including a patient support unit having a patient environment, a heating module, a sensor module, and a control system. The control system is configured to selectively operate the system in a pre-programmed warm-up mode configured to gradually warm the patient in the patient environment according to a series of stepped skin temperature increases performed over a series of stepped time durations to achieve a goal skin temperature. Related apparatus, system, methods and/or articles are described.Type: ApplicationFiled: December 13, 2011Publication date: October 9, 2014Applicants: Dräger Medical GmbH, Draeger Medical Systems, Inc.Inventors: Ulf Timme, Harald Kneuer, Philip Moehring
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Patent number: 8851080Abstract: In one embodiment, the disclosure is directed to an integrated apparatus for delivering energy to a tissue. The integrated apparatus included a housing having a distal end and a tubular structure located within the housing forming a first annulus between the tubular structure and the housing. The tubular structure is configured to accept an energy delivery component and is configured to form a second annulus between the tubular structure and the energy delivery component. The first annulus and the second annulus are configured to communicate with each other proximate to the distal end of the housing.Type: GrantFiled: June 11, 2012Date of Patent: October 7, 2014Assignee: Visualase, Inc.Inventors: Ashok Gowda, Robert McNichols, Marc Gelnett, Matthew Fox
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Publication number: 20140296947Abstract: A warming therapy device including a system for controlling the temperature within an enclosure is provided. The method comprises measuring the temperature of air at a predetermined location inside the enclosure. The method further comprises measuring the humidity inside the enclosure. In addition, the method comprises determining a correction factor to apply to the measured temperature based on the measured humidity. Also, the method includes applying a correction factor to the measured temperature to determine an corrected temperature. The method further includes adjusting the temperature of the air inside the enclosure based on the correction factor.Type: ApplicationFiled: November 10, 2011Publication date: October 2, 2014Applicant: Draeger Medical Systems, Inc.Inventors: Ulf Timme, Jacob Gershteyn
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Patent number: 8845706Abstract: A medical treatment apparatus applies heat to the skin so that the skin may be gradually collapsed without incision and thereby a tumor mass beneath the skin may be exposed to the outside and allowed to be removed. This apparatus includes a cup-like container, oil, and a wick. The container is placed on the first part of the skin that covers a target tumor, and has a vertically penetrated cylindrical shape. The oil is contained in the container and is in contact with the first part of the skin. The wick is placed in the oil so as to catch flame. The temperature of the oil gradually rises while the flame lives on the wick, so heat is continuously applied to the first part of the skin from the oil. This apparatus may further include at least one of a cooling unit and a cooling water pipe placed at an outside of the container, enclosing the container, being in contact with the second part of the skin that is located at the outside of the container, and cooling the second part of the skin.Type: GrantFiled: August 18, 2011Date of Patent: September 30, 2014Inventor: Bok Won Jung
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Patent number: 8845707Abstract: Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood flow past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters. Some cooling catheters are coiled perfusion catheters supporting longer cooling periods by allowing perfusing blood flow simultaneously with vessel wall cooling.Type: GrantFiled: March 28, 2013Date of Patent: September 30, 2014Assignee: Boston Scientific Scimed, Inc.Inventor: Daniel M. Lafontaine
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Publication number: 20140275993Abstract: The present disclosure relates to devices, systems and methods providing evaluation and feedback to an operator of a device providing neuromodulation treatment, such as modulation of renal nerves of a human patient. In one embodiment, for example, a system monitors parameters or values generated before, during, and/or after the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of various physiological parameters of the patient that are relevant to efficacious neuromodulation. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventor: Sowmya Ballakur