Abstract: A fluid dispenser including a fluid reservoir and a body receiving a dispenser member that is connected to the reservoir and an actuator member for actuating the dispenser member; a dispenser and diffuser head forming a fluid dispenser orifice and an application wall for applying the fluid coming from the dispenser orifice onto the skin; a module having a source of radiation emitting monochromatic light of 400 nm to 700 nm and having anti-inflammatory action and/or a stimulating action for stimulating skin-regeneration metabolisms. The dispenser and diffuser head include a source housing and the body includes a module housing communicating with the source housing so that the source of radiation extends in the source housing of the head.

Abstract: Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. The control unit includes a heater/cooler device for providing heated or cooled fluid to a heat exchanger in thermal communication with the fluid heat exchange medium circulating to the heat exchange catheter, a user input device, and a processor connected to receive input from various sensors around the body and the system. A temperature control scheme for ramping the body temperature up or down without overshoot is provided.

Abstract: A device (5) is provided for predicting or simulating a body temperature of a patient (P) at a point in time that is in the future. The device includes a device for determining parameter values concerning the patient (P) and/or the environment thereof. A computing device is provided for simulating a body temperature of the patient (P). A process and a workstation. Are also provided.

Abstract: Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a vascular condition are provided.

Abstract: We disclose methods and medical device systems for selectively recruiting a nerve fiber type within a cranial nerve, a peripheral nerve or a spinal root. Such a method may comprise applying a first pressure, a heating, and/or a cooling to a second location of the nerve, the pressure, heating, or cooling sufficient to substantially block at least one of activation or conduction in at least one fiber population through the second location of the nerve for a blocking time period; and applying an electrical signal to a first location during the blocking time period to prevent or treat an undesirable brain state change.

Abstract: An occupant support includes a mattress 20, a detector 54 and an energy management system comprising thermally conductive pathways and a controller 60. The controller activates one or more selected pathways in response to information from the detector to regulate energy transfer at a detected region of risk 66 on the mattress.

Abstract: In a first embodiment, a portable, battery-operated, minimally invasive small fiber neuropathy testing and diagnostic device, microcontrolled and interfacing with wireless powering to a wireless communications device is being disclosed. Said device is constructed out of an intra-epidermal thermal stimulus consisting of an electronically heated temperature-controlled polymer covered semiconductor material 101 lowered inside the skin through a probe 108 configured with three miniaturized electrodes 109 while a nerve impulse response measurement system records and identifies nerve action potential pulses through a proprietary algorithm. The invention also discloses a detection and characterization method of action potential pulses from neuron cells with respect to their timing such as pulse repetition statistics and rates from a single-point of measurement as diagnostically relevant for determining neuropathies.

Abstract: A modular stimulus applicator system and method are disclosed. The system includes a plurality of wirelessly controlled stimulus pods, anchored to a patient's body, and configured to deliver stimulus to the patient's body. The stimulus can be heat, vibration, or electrical stimulus, or any combination thereof. The stimulus pods are controlled by a control station that can include a user-interface through which the patient can control application of the stimulus.

Abstract: The current invention discloses a treatment device having a heat source, a power source and a heat applicator. The power source includes at least one nanotech battery, ensuring superior properties such as prolonged electricity production and prompt recharging. The heat applicator includes a heat conductive layer made from nanofibers, providing highly efficient heat distribution to the targeted regions. The power source provides energy to the heat source, which generates heat so that the applicator may distribute to an injury site or wound bed of a user. The current device may also be used for cooling, instead of heating applications. In addition to the medical utilizations, the current device may also play a central role in other apparatus that require thermal control capabilities.

Abstract: This invention is directed to a moxibustion therapy device and its use. The moxibustion therapy device comprises a housing, an integrated electric circuit board inside the housing, a power supply module, and a heating module. A protruding portion on one side of the housing is covered with a metal mesh cover. The integrated electric circuit board, the power supply module, and the heating module are connected to one another. The heating module is tightly pressed against one side of the metal mesh cover. Users can use the moxibustion therapy device at anytime anywhere without others' assistance. The moxibustion therapy device can help people expel cold and dampness and relieve pain.

Abstract: Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.

Abstract: A therapeutic device includes an elastomeric outer shell configured as a human hand and defining an interior area, the outer shell having a finger end opposite a wrist end. The device includes a pocket in the interior area, the pocket being defined by an inner wall. An endplate is coupled to the outer shell and coupled to the inner wall to define a closed area between the outer shell and pocket, the endplate having an opening for allowing access to the pocket. A fill material is positioned in the closed area. The device includes a vibrating unit removably positioned in the pocket through the endplate opening, the vibrating unit having a lock complementary to a catch to couple the vibrating unit to the endplate, the vibrating unit having a vibrating motor in electrical communication with a power source and a switch.

Abstract: Devices and methods for providing therapeutic heating are disclosed herein. In one embodiment, the system includes a device body configured to provide heat to a portion of skin. The device body also includes a low-level heating region and a high-level heating area. The low-level heating region provides a continuous amount of heat at a first temperature, and the high-level heating area provides an intermittent amount of heat at a second temperature greater than the first temperature.

Abstract: A method for expressing a homeostatic function activating gene, comprising a step of applying a thermal stimulus, which is lower than 50 degrees Celsius, to at least a stimulus application origin part, which is a part between first and second toes of left or right foot sole, and which is located at an intersection of an extended line of a medial edge and a vertical line of the medial malleolus, by using an electric type warm temperature heating stimulus apparatus, thereby increasing a blood volume.

Abstract: A device for stimulating hair growth applied to a user's scalp. The device includes a housing. A plurality of light emitting diodes coupled to the housing operable to emit non-coherent light, the non-coherent light having at least two intensity peaks. A plurality of pairs of teeth extending from the housing, wherein the plurality of light emitting diodes are disposed between each pair of teeth; and wherein each of the plurality of pairs of teeth parts the user's hair to expose the scalp.

Abstract: Embodiments of the invention disclosed herein generally include methods and/or devices for increasing blood flow, controlling the vasodilatation of a patient's vascular structure, regulating the temperature of a portion of a mammal, and for improving various interventional procedures and/or therapeutic techniques. The device may also include one or more access ports, or apertures, that allow access to portions of the mammal's extremity to allow interventional type medical devices, therapeutic devices, surgical support equipment or patient monitoring devices to have access to the extremity on which a body element is disposed. The device may also be configured to allow other supporting components, which may include IV or other catheters, a means of accessing to a portion of the extremity positioned inside the temperature regulating device.

Abstract: A personal artificial transpiration cooling system having a transpiration surface with a substrate, a transpiration membrane layer which is spaced from the substrate layer by one or more spacers to define one or more interior fluid flow channels between a first surface of the transpiration membrane layer and the substrate; and a stoma layer disposed adjacent a second surface of the permeable membrane layer, the stoma layer being spaced from the second surface of permeable membrane layer by a predetermined distance to define one or more cavities disposed between pores in the at least one stoma layer and the second surface of the permeable membrane layer. A fluid reservoir is provided in fluid communication with the one or more interior fluid flow channels, while the transpiration surface is configured to be worn by a human or an animal and the fluid reservoir is designed to be supported, in use, by the human or animal wearing the transpiration surface.

Abstract: A contact cooler for thermal conditioning a surface is disclosed. The contact cooler may include a temperature controller assembly with recirculating temperature controlled fluid for heating and/or cooling a surface of a patient in contact with a cooling head. The cooling head may be attached to a handle for manual manipulation thereof.

Abstract: An apparatus for determining a thermal property of tissue includes a base unit with one or more energy source and at least two, preferably detachable, leads. The distal end of each lead, which is introduced into the tissue to be treated, has at least two longitudinally spaced temperature measuring elements to measure surrounding tissue temperature and at least two longitudinally spaced electrode surfaces for applying current to the tissue. Each distal end is also provided with an element which uses energy emitted by the sources of energy to heat up the surrounding tissue. The base unit has computing elements, current generating elements for generating an alternating current, and conductance determining elements for determining the tissue conductance between pairs of electrode surfaces based on the alternating current applied by the current generating elements to the tissue. Methods for using the device and leads for use in the device are also described.

Abstract: Computerized system and method for livestock groups health monitoring comprising: a storage and computing unit storing at least one database; a plurality of data collecting units of different types, each type comprising at least one sensor, the data collecting unit types selected from the group consisting of acoustic sensors, vitality meters, ammonia sensors, visual sensors and scent sensors; first communication means for communicating operating commands from the storage and computing unit to each of the data collecting units and for communicating data from the data collecting units to the storage and computing unit ; and second communication means for communicating between the storage and computing unit and a user device.

Abstract: A device that is used to reduce the pain of a needle stick to a person, the device having a casing containing a vibratory device and a temperature reducing device, and a method for using the device to reduce the pain of a needle stick by applying both thermal and vibration analgesia to a subject during a needle stick.

Abstract: A device for treating spinal tissue of a patient's body may include an energy source and first and second probe assemblies. Each of the probe assemblies may have an electrically conductive energy delivery device electrically coupled to the energy source, and may also have an electrothermal device for cooling the probe assembly. The device is configured so that the energy source delivers energy to the spinal tissue through the energy delivery devices in a bipolar mode that concentrates delivered energy between the energy delivery devices to create a lesion within the spinal tissue while the electrothermal devices cool the probe assemblies. Related methods of use include cooling, at times via an electrothermal device.

Abstract: This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.

Abstract: Disclosed herein, among other things, is system for thermal neuroinhibition. According to an embodiment, the system includes at least one implantable fluid-filled conduit adapted to be placed adjacent to a neural target. The system also includes an implantable housing including a power source, a heat pump deriving power from the source and connected to the conduit, and a controller within the housing. The controller is connected to the heat pump, and is adapted to control the heat pump to effect fluid flow in the conduit to cool the neural target using electromechanical refrigeration to reversibly inhibit neural activity as part of a medical treatment.

Abstract: Devices, systems, and related methods for electric fields delivery for preferential destruction of cancerous cells and tissue ablation.

Abstract: Intra-vaginal devices and methods are disclosed for a broad range of applications in the women's health field. The devices and methods provide for placement in the cervical region, and for transferring heat to a cervical region, a barrier contraception method, collection of menstrual fluid, and release of drugs and/or hormones intra-vaginally. The device also can address multiple women's health issues.

Abstract: Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.

Abstract: Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.

Abstract: Methods and apparatus for the prevention and treatment of shivering encountered during therapeutic temperature regulation are disclosed that utilize an active system of counterwarming such that the timing and intensity of warmth provided to selected body areas is regulated dynamically in response to such factors as the extent of cooling applied to the core, the degree of shivering encountered, and patient temperature. Additionally, methods and apparatus are disclosed for the measurement and quantification of shivering for use in this and other applications.

Abstract: A therapeutic apparatus comprising a high intensity focused ultrasound system (302) for sonicating a sonication volume (324) of a subject (320). The therapeutic apparatus further comprises a magnetic resonance imaging system (300) for acquiring magnetic resonance thermometry data (350) within an imaging volume (316). The sonication volume is within the imaging volume. The therapeutic apparatus further comprises a controller (304) for controlling the therapeutic apparatus. The treatment plan comprises instructions for controlling the operation of the high intensity focused ultrasound system. The controller is adapted for sonicating (100) the target volume using the high intensity focused ultrasound system. The controller is adapted for repeatedly acquiring (102) magnetic resonance thermometry data using the magnetic resonance imaging system during execution of the treatment plan.

Abstract: The present invention is directed to a reusable pain relieving treatment device, such as a belt, and a disposable thermal device having one or more thermally conductive components that extend from a surface of the device and are capable of transferring heat, cold or vibrations from disposable or reusable devices to targeted sections of the user's body.

Abstract: A method for providing localized heating of the dermal layers of skin of a patient, using energy in the form of a group of pulses having defined parameters in a controlled manner. This method preferably uses an optical delivery system to deliver pulsed energy to a specific spot of skin so that targeted layers of the affected skin are heated to a desired temperature range. The temperature range is optimally selected to maximize treatment efficacy while minimizing pain to the patient. Example applications include reducing wrinkles, acne, hair, scar tissue, warts, and promoting wound healing. In this method, the temperature of the selected locus rises quickly to the desired temperature range, then is maintained within a controlled range with a relatively flat temperature profile. The method maintains the temperature by controlling one or more of a pulse energy intensity, pulse width, and pulse frequency or time delay between pulses.

Abstract: An electroporation device produces electric signals that may be adjusted in response to a cover area of electrodes, so that the electric signals are tolerable when delivered to cells within the cover area. The electroporation device can include an applicator, a plurality of electrodes extending from the applicator, a power supply in electrical communication with the electrodes, and a guide member coupled to the electrodes. The electrodes are associated with a cover area. The power supply is configured to generate one or more electroporating signals to cells within the cover area. The guide member can be configured to adjust the cover area of the electrodes. In some embodiments, the electrical signals may include opposing waveforms that produce a resultant interference waveform to effectively target the cover area, and each waveform may be a unipolar waveform or a bipolar waveform.

Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

Abstract: A system and method for portably delivering a therapeutic dose of heat to the skin to relieve pain, reduce accommodation of thermal nerve receptors, promote healing, and deliver transcutaneous medications. The heating device is user programmable or pre-programmed to deliver according to a variety of cycles, patterns and algorithms. The cycles, patterns, and algorithms of the heat are programmable parameters, are under the user's control, and increase the effectiveness and efficiency of the device. The heating algorithms are designed to interact with an individual user's thermal nerve receptors and other tissue characteristics and to reduce the tendency of the receptors to accommodate to the external stimuli with back pain, muscular pain, dysmenorrhea, headaches, fibromyalgia, post-herpetic neuralgia, nerve injuries and neuropathies, and sprains and strain.

Abstract: A technique for detecting and providing alerts or indications that can be used for controlling or altering the displacement speed of an applicator coupling skin heating energy across a treated skin. A temperature sensor monitors the rate of skin temperature change and provides feedback related to altering the applicator displacement speed according to the rate of skin temperature change. Disclosed is also an applicator for implementing this method.

Abstract: A nerve tissue stimulator configured for contacting to or insertion in the body of a subject to stimulate a tissue therein, said probe comprising: (a) a support configured for contacting to or positioning adjacent a tissue of said subject; (b) at least one thermoelectric device (TED) on said support and positioned for thermally stimulating said nerve tissue.

Abstract: An apparatus for treating meibomian gland dysfunction caused by meibomian gland obstruction in order to restore the natural flow of secretion from the meibomian gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Abstract: Particles and related methods are disclosed.

Abstract: A system for controlling temperatures during medical procedures is disclosed. The system can include a high-thermal conductivity matrix with embedded thermal capacitors. The matrix can be a cream or gel, for example, and can enable the system to be easily applied to the skin, or other area to be treated. The thermal capacitors can include phase change materials, polymers, fats, or other materials that undergo an endothermic physico-chemical transformation above a first predetermined temperature (e.g., room temperature), but below a second predetermined temperature (e.g., the patient's pain threshold). The system can further include one or more thickeners to provide the desired rheological properties for application. The system can also include one or more lubricants to ease some operations during the medical procedure.

Abstract: Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.

Abstract: An improved heating pad which minimizes or eliminates skin burns due to improper uses in three ways: by monitoring an absolute temperature of each surface of the heating pad; by monitoring a temperature difference between each surface of the heating pad, where a small temperature difference indicates that both sides of the heating pad are covered; and by monitoring the duty cycle of a heating element, where a large off portion of the duty cycle indicates both sides of the heating pad are covered.

Abstract: A surgical operating room table pad that functions in multiple capacities such as a dielectric capacitor for grounding the electro-surgical current from cautery device and heating the patient contact surface for the maintenance of patient normal-thermia. The “capacitor/dielectric” is designed to allow the electrosurgical current introduced to the patient to return back to the electrosurgical generator for patient and surgical staff safety. The temperature of the patient's body is constantly measured by a series of RTD Thermister sensors and a resistive device is utilized for thermal input.

Abstract: A system is described for removing heat from a subject's subcutaneous lipid-rich regions, such as tissues, organs, cells, and so forth. In various embodiments, the system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The system can employ these components to receive a selection of a treatment profile and apply the selected treatment using an applicator. The treatment profile may be received from a patient protection device that connects to an applicator.

Abstract: A limited use or disposable nonwoven blanket including at least one spunlace layer having an inner surface and outer surface and at least one continuous filament layer having an inner surface and outer surface, wherein the outer surface of the continuous filament layer is metallized. The limited use or disposable nonwoven blanket further includes at least one heating element proximate to the metallized surface of the continuous filament layer.

Abstract: There is provided a stimulus generation apparatus including a stimulus generation section which provides a stimulus for promoting fat burning for fat or a satiety center inside a body cavity.

Abstract: A balloon catheter is used in a closed-loop heat exchange system for manipulating the temperature of a patient. The balloon catheter is positioned in the stomach of the patient, and then expanded with a heat exchange fluid delivered through a lumen formed in the shaft of the catheter. The balloon catheter comes into contact with the wall of the stomach, and the stomach substantially conforms around the expanded balloon catheter. The heat exchange fluid is allowed to flow continuously into and out of the balloon catheter. Heat is exchanged between the balloon catheter and the stomach so as to controllably alter the temperature of at least a portion of the patient. Anti-shivering mechanisms and automatic control based on temperature feedback from the patient may be used in connection with the heat exchange system.

Abstract: A physiological thermal stimulation probe, comprising: (a) an electrically controlled heat control element with a relatively low thermal capacity and adapted for contact with tissue on one side thereof; (b) a thermal sink/source with a relatively high effective thermal capacity and a relatively low thermal impedance, such that said thermal sink/source sink can rapidly change a temperature of said heat control element, at a rate above 10 degrees Celsius per second, from a temperature of below 100 degrees Celsius; and (c) circuitry which activates said heat control element to achieve a desired temperature stimulation profile of said tissue.

Abstract: A patient temperature control system (10) uses variable temperature gradient warming/cooling in combination with a warming/cooling device (16), such as a blanket, to increase efficiency in driving a patient's temperature to a desired setpoint, with reduced occurrence of and magnitude of overshoot conditions. In operation, the controller (26) of the system (10) senses the temperature of a patient (12) via a sensor (31), for comparison to a temperature of the circulating water, sensed via sensor (30). If the patient temperature is not sufficiently close to a setpoint temperature, the system (10) is operable to warm/cool the circulating water to a temperature which differs from the patient's temperature by a temperature gradient of 10 ° C., or some other preselected initial temperature gradient.

Abstract: Techniques are provided for use with an implantable cardiac rhythm management (CRMD) system equipped to deliver neurostimulation to acupuncture sites within anterior regions of the neck, thorax or abdomen of the patient. Parameters associated with the health of the patient are detected, such as parameters indicative of arrhythmia, heart failure and hypertension.