Chemical Analysis Patents (Class 702/22)
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Patent number: 7859674Abstract: A system and method for measuring a quality parameter of a harvested crop are provided. Specifically, the system is adapted to be carried by a harvesting device such that a sensor is enclosed in a controlled environment and such that the sensor is capable of precisely and reliably measuring the quality parameter while the harvesting device is in operation. The system includes a verification device and an actuator device contained within the controlled environment. The actuator device periodically conveys the sensor device to at least one of a verification position relative to the verification device and a measurement position. Thus, the sensor device may be periodically and reliably referenced and/or validated while in use in harsh agricultural environments such that the sensor device is capable of accurately measuring the quality parameter as the crop is harvested.Type: GrantFiled: November 19, 2007Date of Patent: December 28, 2010Assignee: Pioneer Hi-Bred International, Inc.Inventors: Wilhelm G. Greten, Carlos Hildebrand, Roland Welle
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Patent number: 7853407Abstract: The present invention provides systems and methods for improving the administration and usage of antibiotic/antimicrobial regimens. The method and system of the invention includes (a) establishing a multidisciplinary antimicrobial treatment team; (b) obtaining patient data; (c) reviewing patient data for sub-optimal antibiotic regimens and when necessary, conferring if MATT members regarding regimen recommendations; (d) generating reports with recommendations for optimal antibiotic regimens based on the review of the patient data.Type: GrantFiled: January 6, 2005Date of Patent: December 14, 2010Assignee: Bluarc Health LLCInventor: Robert W. Yancey, Jr.
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Publication number: 20100304252Abstract: A method is generally described which includes altering the temperature of an electrical energy storage device or an electrochemical energy generation device includes configuring a controller with a control algorithm to control the actions of a fluid control system as a function of current draw from the electrical energy storage device or the electrochemical energy generation device, the electrical energy storage device or the electrochemical energy generation device configured to provide electrical current. The method also includes providing A microchannel thermal control system for the electrical energy storage device or the electrochemical energy generation device. The microchannel thermal control system is configured to cool at least portions of the electrical energy storage device or the electrochemical energy generation device.Type: ApplicationFiled: May 26, 2009Publication date: December 2, 2010Inventors: Alistair K. Chan, Roderick A. Hyde, Jordin T. Kare, Lowell L. Wood, JR.
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Publication number: 20100294927Abstract: The various embodiments provide methods and apparatus high-throughput reading and decoding of information-encoding features (especially identification features) on pharmaceutical compositions for the purpose of e.g. counterfeiting detection and inventory tracking/tracing. A preferred embodiment provides high-throughput imaging of regular arrays of pharmaceutical tablets with a scanning electron microscope. Another preferred embodiment provides video-rate scanning probe imaging of pharmaceutical compositions and especially atomic force microscopy imaging thereof.Type: ApplicationFiled: September 12, 2006Publication date: November 25, 2010Inventors: Michael Nelson, Sylvain Cruchon-Dupeyrat, Bjoern Rosner, Cedric Loiret-Bernal
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Patent number: 7837622Abstract: A recording medium includes a sensor circuit unit generating a current in accordance with a blood glucose level in blood, and a control unit calculating blood glucose level data from the data obtained by digital conversion of the generated current at signal processing unit, writing the calculated data to an EEPROM as a memory unit, reading the blood glucose level data from EEPROM and transmitting the same to a portable terminal on which recording medium is mounted, through a communication control unit. The recording medium further includes a power supply control unit receiving power from the portable terminal on which the recording medium is mounted, and supplying power to various portions in the recording medium.Type: GrantFiled: August 6, 2002Date of Patent: November 23, 2010Assignee: Nipro CorporationInventors: Takehito Itoh, Hideyuki Tomita
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Patent number: 7840359Abstract: Methods and systems are provides for measuring multi-dimensional sensing information for identification purposes. The identity of one or more substances is determined through analysis of multidimensional data that can include, among others, intrinsic information as well as extrinsic information. The method for identification of a substance comprises utilizing pattern recognition to form descriptors to identify characteristics of the substance. A system and computer program for performing analysis of the multidimensional data are also described.Type: GrantFiled: March 20, 2009Date of Patent: November 23, 2010Assignee: Smiths Detection Inc.Inventors: Chang-Meng B. Hsiung, Jing Li, Beth Munoz, Ajoy K. Roy, Michael G. Steinthal, Steven A. Sunshine, Michael A. Vicic, Shou-Hua Zhang
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Patent number: 7840361Abstract: A technology is provided in which it is not necessary to modify a system on a production side, and in which man-hours required for registering an environmental load value on a supplier side are not increased, in cases of an item having a mismatch between units, in a process of adding up the environmental load values of a post-production product. The technology includes generating correction information for calculating the environmental load that is registered by the supplier at design time, and calculating the environmental load value at design time by using the correction information. In cases of calculating the environmental load value of a product actually produced from a designed product, the environmental load value is calculated using the correction information generated at design time.Type: GrantFiled: November 21, 2007Date of Patent: November 23, 2010Assignee: Hitachi, Ltd.Inventors: Takaaki Kumazawa, Noriaki Yamamoto, Yoshiharu Sekiya
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Patent number: 7840363Abstract: System and method for determining total mill flow (TMF) in a biofuel production process. Measured slurry flow and density values from a process fed by mill(s), backset, and at least one water source, are received. The slurry includes biomass solids and water. Measured backset flow and density values, and a backset composition value are received, as well as a slurry composition value indicating % biomass solids of the slurry is received. A quantity of biomass solids and/or water of the slurry determined based on the slurry flow, density, and composition, and a quantity of the biomass solids and/or water of the backset determined based on the backset flow and density, backset composition, and a system filter characterizing time delays and lags between measurements of the backset flow and biomass slurry flow. Total mill flow is determined based on the quantities of biomass solids and/or water of the slurry and backset.Type: GrantFiled: March 20, 2008Date of Patent: November 23, 2010Assignee: Rockwell Automation Technologies, Inc.Inventors: Brian K. Stephenson, Patrick D. Noll, Maina A. Macharia
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Patent number: 7838297Abstract: A method of optimizing operation of a fossil fuel fired boiler includes, in an exemplary embodiment, providing a plurality of sensors positioned in different spatial positions within the fossil fuel fired boiler. The method also includes recording sensor outputs, identifying spatial combustion anomalies indicated by sensor outputs, identifying burners responsible for the spatial combustion anomalies, and adjusting air flow of responsible burners to alleviate the spatial combustion anomalies.Type: GrantFiled: March 28, 2003Date of Patent: November 23, 2010Assignee: General Electric CompanyInventors: Neil Colin Widmer, Roy Payne, William Randall Seeker, Philippe Jean Gauthier
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Patent number: 7837966Abstract: Ozone and, if necessary, water is added to an exhaust gas, such as air, containing hydrogen- and carbon-containing molecules of a pollutant. The exhaust gas is then continually flowed into one or more oxidizing reaction chamber modules. In the reaction chamber(s) the ozone- and water-containing gas is subjected to intense ultraviolet radiation (wavelength of 254 nm) to promote the formation of hydroxyl radicals to oxidize the pollutant molecules to carbon dioxide and water. The continually discharged gas is analyzed for residual ozone and hydrocarbon content and the analytical data used in feedback control of ozone addition and UV radiation intensity.Type: GrantFiled: February 23, 2005Date of Patent: November 23, 2010Assignee: GM Global Technology Operations, Inc.Inventors: Kenneth B. Gross, Daniel Dziedzic, John T. Johnson
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METHOD AND APPARATUS FOR ESTIMATING FEATURES OF TARGET MATERIALS BY USING KINETIC CHANGE INFORMATION
Publication number: 20100292932Abstract: Disclosed are a method and an apparatus for estimating the features (concentration, weight, volume, etc.) of target materials, by using kinetic change information along time, when measuring the results of a chemical reaction between two materials, target materials and reactant, with an optical or electrochemical method. More precisely, the disclosed method and apparatus obtain in advance the correlation between accurate feature values of the target materials measured by a reference equipment and the kinetic change information related to the feature values of the target materials which is varying along the passage of time and indicates the results of chemical reaction measured by an optical or electrochemical method, and then estimates the feature values of the new samples using the correlation and the kinetic change information obtained from the new sample.Type: ApplicationFiled: January 21, 2009Publication date: November 18, 2010Inventor: YONG GWAN WON -
Patent number: 7835872Abstract: Methods and systems are provided for the deconvolution of the NMR spectrum of a mixture into individual components and spin systems by combining covariance total correlation spectroscopy (TOCSY) spectra with covariance NMR. The method may include obtaining a 2D TOCSY spectra of a chemical mixture and then performing a series of analytical steps to identify the individual components of the mixture.Type: GrantFiled: February 18, 2008Date of Patent: November 16, 2010Assignee: Florida State University Research FoundationInventors: Rafael Bruschweiler, Fengli Zhang
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Patent number: 7836102Abstract: A method and system for enhancing software documentation and help systems. In one embodiment, a virtual library for a selected combination of tools is created. The virtual library is then linked to the tools in the selected combination of tools. In another embodiment, a combination of tools for designing a complex software system is selected from one or more software releases. The one or more software releases comprises a plurality of available tools. The selected combination of tools comprises less than all of the plurality of available tools. Each of the plurality of available tools is associated with one or more documents. Access to only those one or more documents associated with tools in the selected combination of tools is provided.Type: GrantFiled: December 29, 2008Date of Patent: November 16, 2010Assignee: Cadence Design Systems, Inc.Inventor: Gurbir Singh
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Patent number: 7828743Abstract: A temperature sensing device accurately determines the core temperature of a warm blooded animal or human based on at least one measurement of the temperature of the skin of the warm blooded animal or human. The device includes a housing, and a first contact type temperature sensing element coupled to the housing. The first contact type temperature sensing element includes a first temperature sensor that is operative to measure the temperature of the skin when the first contact type temperature sensing element is in contact with the skin. The first temperature sensor produces at least a first signal representative of the measured skin temperature. An electronic circuit uses the first signal to determine the core temperature of the warm blooded animal or human. An electronic communication device, such as a display, is coupled to the electronic circuit for communicating the core temperature to a user.Type: GrantFiled: November 29, 2006Date of Patent: November 9, 2010Assignee: Advanced Monitors CorporationInventor: Jacob Fraden
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Patent number: 7826981Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: GrantFiled: January 18, 2005Date of Patent: November 2, 2010Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath
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Patent number: 7826980Abstract: A sensitivity of a cumulative chemical/physical phenomenon detecting apparatus is improved. Prior to transferring charges at a sensing section to a floating diffusion section, the charges remaining at the sensing section are removed from the sensing section by a potential barrier formed between the sensing section and a charge injection adjusting section.Type: GrantFiled: March 13, 2006Date of Patent: November 2, 2010Assignee: National University Corporation Toyohashi University of TechnologyInventors: Kazuaki Sawada, Takeshi Hizawa, Junichi Matsuo, Yuki Maruyama
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Patent number: 7826974Abstract: Apparatus and methods of using the apparatus for inducing movement and interaction of molecules in an electric field of an electrophoretic device that is circular in configuration to mimic a living cell. The circular electrophoretic device supports an isoelectric focusing medium, such as a gel on a gel plate with one charged circular pole at the center and an oppositely charged concentric pole at the perimeter of the plate whereupon molecular substances having electronegative or electropositive charges placed in the gel will tend to migrate toward the oppositely charged pole to their isoelectric points, allowing researchers to devise experiments with multiple substances to track pathways of interaction during osmotic diffusion and polar directed migration through the medium that parallel pathways in a biological cell, the device having a thermal control for regulating the temperature of the analytical experiments using the device.Type: GrantFiled: June 29, 2004Date of Patent: November 2, 2010Inventors: Roulette W. Smith, Robert R. Shadel
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Publication number: 20100273068Abstract: A fuel cell system includes a fuel tank, a replaceable fuel filter, a fuel cell stack, and a control system. The fuel tank includes raw fuel stored therein. The replaceable fuel filter member includes a filter property indicator and is configured to receive raw fuel from the fuel tank and to refine the raw fuel to a refined fuel. The fuel cell stack is configured to receive refined fuel from the fuel filter and to utilize the refine fuel to generate electricity and a control system configured to access the filter property indicator of the fuel filter member.Type: ApplicationFiled: April 22, 2009Publication date: October 28, 2010Applicant: ADAPTIVE MATERIALS, INC.Inventors: Aaron T. Crumm, John Muczynski, Mike Gorski, Jason Krajcovic
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Publication number: 20100273069Abstract: A fuel cell system includes an energy conversion module and a fuel module that is detachable from the energy conversion module. The fuel module includes a fuel tank, a fuel module identification member including fuel module data and a fuel filter member. The control module is configured to access the fuel module data from the fuel module identification member. The fuel cell stack is configured to utilize the refined fuel to generate electrical energy.Type: ApplicationFiled: April 22, 2009Publication date: October 28, 2010Applicant: ADAPTIVE MATERIALS, INC.Inventors: Aaron T. Crumm, John Muczynski, Mike Gorski, Nathan Ernst, Jason Krajcovic
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Publication number: 20100262380Abstract: The present invention includes analyte measurement systems, analyte measurement meters, analyte testing devices, cartridges thereof and integrated circuits for use therewith, and further includes methods related to the use of the integrated circuits and, in certain embodiments, to the counting or tracking of parameters related to the cartridges and analyte test devices.Type: ApplicationFiled: September 22, 2009Publication date: October 14, 2010Inventors: William Matievich, JR., Alexander G. Ghesquiere, Ting Chen
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Patent number: 7811824Abstract: A method of monitoring the properties of a biological or chemical sample. The method includes carrying out a plurality of different tests on the sample to generate corresponding test data; optionally carrying out a preliminary processing of the test data to generate partially processed data; storing the test data and/or partially processed data; causing a processing system to analyze a user-defined selection of the test data or partially processed data to generate result data relating to one or more properties of the sample; and subsequent to the previous step, receiving a second user defined selection of the test data or partially processed data, different from the first selection, and causing the processing system to analyze the second user-defined selection of the test data or partially processed data to generate second result data relating to one or more properties of the sample different from the properties corresponding to the first user-defined selection.Type: GrantFiled: March 30, 2006Date of Patent: October 12, 2010Assignee: Randox Laboratories LimitedInventors: John Victor Lamont, Robert Ivan McConnell, Stephen Peter Fitzgerald
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Patent number: 7811827Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.Type: GrantFiled: July 1, 2008Date of Patent: October 12, 2010Assignee: Momenta Pharmaceuticals, Inc.Inventor: Sasisekharan Raguram
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Publication number: 20100256918Abstract: An apparatus for detecting an object capable of emitting light. The apparatus comprises a light detector comprising at least two optical sensors capable of determining the intensity of the light; and a computer processing output signal generated by the optical sensors and comparing a result of the processing with a known result corresponding to a known type to determine whether the object belongs to the known type.Type: ApplicationFiled: March 9, 2010Publication date: October 7, 2010Inventors: Hung-Chun Chen, Ming-Chia Li, Chang-Sheng Chu, Yu-Tang Li, Chung-Fan Chiou
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Publication number: 20100253527Abstract: A method and an apparatus for detecting the release of a chemical, biological, or radiological agent are disclosed. In some embodiments, a microphone is used to continuously monitor sound and acquire acoustic data and a sensor is used to substantially continuously monitor a property that is related to a chemical, biological, or radiological agent. The acoustic data is analyzed for a signature that is distinguishable from background sound. The sensor data is analyzed for an event that is indicative of the release of a chemical, biological, or radiological agent. The acoustic signature, and the time at which it is observed, is used to corroborate the sensor data.Type: ApplicationFiled: September 28, 2006Publication date: October 7, 2010Applicant: LOCKHEED MARTIN CORPORATIONInventors: Francesco Pellegrino, Edward J. Vinciguerra
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Patent number: 7809526Abstract: This invention relates to any fossil fueled thermal system, and especially relates to large commercial steam generators used in power plants, and, more particularly, to a method and apparatus for determining fuel chemistry in essentially real time based on effluents resulting from combustion, associated stoichiometrics, and the genetics of the fossil fuel. Knowing the system's fuel chemistry, the fuel calorific value, the fuel flow and the thermal performance associated with the thermal system may then be determined in essentially real time.Type: GrantFiled: January 17, 2008Date of Patent: October 5, 2010Assignee: Exergetic Systems, LLCInventor: Fred D. Lang
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Patent number: 7809540Abstract: In the present invention the NonRandom Two-Liquid segment activity coefficient model system of the parent application is extended for computation of ionic activity coefficients and solubilities of electrolytes, organic and inorganic, in common solvents and solvent mixtures. The invention method and system may be applied to the chemical and/or pharmaceutical design process. In addition to the three types of molecular parameters defined for organic nonelectrolytes, i.e., hydrophobicity X, polarity Y, and hydrophilicity Z, an electrolyte parameter, E, is introduced to characterize both local and long-range ion-ion and ion-molecule interactions attributed to ionized segments of electrolytes. Successful representations of mean ionic activity coefficients and solubilities of electrolytes, inorganic and organic, in aqueous and nonaqueous solvents are presented.Type: GrantFiled: September 30, 2005Date of Patent: October 5, 2010Assignee: Aspen Technology, Inc.Inventors: Chau-Chyun Chen, Yuhua Song
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Patent number: 7809510Abstract: Positional Hashing, a novel method for detecting similarities between texts such as DNA sequences, amino acid sequences, and texts in natural language is disclosed. The method is particularly well suited for large-scale comparisons such as that of mutual comparisons of millions of sequence fragments that result from mammalian-scale sequencing projects and for whole-genome comparisons of multiple mammalian genomes. Positional Hashing is carried out by breaking the sequence comparison problem along its natural structure, solving the subproblems independently, and then collating the solutions into an overall result. The decomposition of the problem into subproblems enables parallelization, whereby a large number of nodes in a computer cluster or a computer farm are concurrently employed on solving the problem without incurring the quadratic time performance penalty characteristic of prior art.Type: GrantFiled: February 26, 2003Date of Patent: October 5, 2010Assignee: IP Genesis, Inc.Inventor: Aleksandar Milosavljevic
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Publication number: 20100242440Abstract: According to one exemplary embodiment, an apparatus is disclosed for estimating an NOx conversion efficiency of an SCR catalyst. The apparatus includes a catalyst degradation module for determining an SCR catalyst degradation factor and a NOx concentration module for determining an SCR catalyst inlet NOx concentration based on an interpretation of at least one NOx detector signal. Additionally, the apparatus includes an NH3 concentration module for determining an SCR catalyst inlet NH3 concentration, a temperature module for determining an SCR catalyst bed temperature of the at least one SCR catalyst, and a space velocity (SV) module for determining an exhaust gas SV for the SCR catalyst. A NOx conversion efficiency module calculates a NOx conversion efficiency value based at least partially on the SCR catalyst degradation factor, the SCR catalyst inlet NOx concentration, the SCR catalyst inlet NH3 concentration, the exhaust gas SV, and the SCR catalyst bed temperature.Type: ApplicationFiled: December 7, 2009Publication date: September 30, 2010Applicant: CUMMINS IP, INC.Inventors: Phanindra Garimella, Andy Osburn, John N. Chi, Joan M. Wills
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Patent number: 7805253Abstract: Accordingly, systems and methods for protein identification are provided. The present teaching provide for a system with one protein identification methodology based on one method and a second protein identification methodology based on a second protein identification methodology to interact and increase confidence in protein identification. Various embodiments employ protein identification methodologies that identify portions of a peptide. Various embodiments provide for a hypothesis generation module that can suggest modifications for the peptide based on differences between experimental and theoretical values. Various embodiments provide for an identifier module that can select one or more hypotheses from the hypothesis module as most probable. In this way, the present teachings can provide for systems and methods to combine protein identification results from multiple protein identification methodologies with the possibility of identifying modifications.Type: GrantFiled: August 31, 2005Date of Patent: September 28, 2010Assignee: DH Technologies Development Pte. Ltd.Inventors: Xunming Chen, Philip J. Savickas, Marvin L. Vestal, Xiangping Zhu
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Patent number: 7805388Abstract: In a pre-processing step prior to training a learning machine, pre-processing includes reducing the quantity of features to be processed using feature selection methods selected from the group consisting of recursive feature elimination (RFE), minimizing the number of non-zero parameters of the system (l0-norm minimization), evaluation of cost function to identify a subset of features that are compatible with constraints imposed by the learning set, unbalanced correlation score, transductive feature selection and single feature using margin-based ranking. The features remaining after feature selection are then used to train a learning machine for purposes of pattern classification, regression, clustering and/or novelty detection.Type: GrantFiled: October 30, 2007Date of Patent: September 28, 2010Assignee: Health Discovery CorporationInventors: Jason Weston, André Elisseeff, Bernhard Schölkopf, Fernando Perez-Cruz, Isabelle Guyon
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Patent number: 7805256Abstract: A method of processing time-discrete measured values, which can be described in their time characteristic by a first exponential function which has a first time constant, the method comprising the steps of: detecting a first measured value and storing the first measured value, detecting a second measured value and storing the second measured value according to a defined time interval with respect to the detection of the first measured value, filtering the first measured value and second measured value by calculating a sum of the first measured value and a weighted difference between the second measured value and the first measured value, thereby generating time-discrete output values which can be described in their time characteristic by a second exponential function having a second time constant different from the first time constant, and outputting the output values is disclosed.Type: GrantFiled: April 18, 2007Date of Patent: September 28, 2010Assignee: Vincotech (Germany) GmbHInventor: Robert Frodl
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Patent number: 7805255Abstract: Fixed bond information is derived. A fixed bond representation of a chemical structure is derived from a delocalized representation. A path is conceptually traced through the represented structure and an examination is conducted, for each atom, of each possible electronic and bonding state that is consistent with what has come before along the path. A result is found by extensively or exhaustively examining all possible states and orders in a semi-recursive procedure that is directed early towards likely answers. If there is more than one possible solution, the best solution is chosen by use of a rating function.Type: GrantFiled: November 13, 2007Date of Patent: September 28, 2010Assignee: CambridgeSoft CorporationInventor: Harold E. Helson
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Patent number: 7804062Abstract: A method of obtaining pure component mass spectra or pure peak elution profiles from mass spectra of a mixture of components involves estimating number of components in the mixture, filtering noise, and extracting individual component mass spectra or pure peak elution profiles using blind entropy minimization with direct optimization (e.g. downhill simplex minimization). The method may be applied to deconvolution of pure GC/MS spectra of overlapping or partially overlapping isotopologues or other compounds, separation of overlapping or partially overlapping compounds in proteomics or metabolomics mass spectrometry applications, peptide sequencing using high voltage fragmentation followed by deconvolution of the obtained mixture mass spectra, deconvolution of MALDI mass spectra in the separation of multiple components present in a single solution, and specific compound monitoring in security and/or environmentally sensitive areas.Type: GrantFiled: April 4, 2007Date of Patent: September 28, 2010Assignee: National Research Council of CanadaInventors: Juris Meija, Zoltan Mester
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Publication number: 20100241360Abstract: Methods, data structures, and systems for classifying particles are provided. In particular, the methods and systems are configured to acquire a first set of data corresponding to measurable parameters of a microparticle and identify a location of a look-up table to which the first set of data corresponds, wherein the look-up table is framed by values associated with at least one of the measurable parameters. Furthermore, the methods and systems are configured to determine whether the first set of data fits one or more predefined algorithms respectively indicative of a different microparticle classification associated with the identified location of the look-up table. The methods and systems are further configured to classifying the microparticle within at least one predefined categorization based upon the determination of whether the first set of data fits the one or more predefined algorithms.Type: ApplicationFiled: August 1, 2006Publication date: September 23, 2010Applicant: LUMINEX CORPORATIONInventors: Edward A. Calvin, Wayne D. Roth
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Patent number: 7801687Abstract: Methods for using modified single wall carbon nanotubes (“SWCNTs”) to detect presence and/or concentration of a gas component, such as a halogen (e.g., Cl2), hydrogen halides (e.g., HCl), a hydrocarbon (e.g., CnH2n+2), an alcohol, an aldehyde or a ketone, to which an unmodified SWCNT is substantially non-reactive. In a first embodiment, a connected network of SWCNTs is coated with a selected polymer, such as chlorosulfonated polyethylene, hydroxypropyl cellulose, polystyrene and/or polyvinylalcohol, and change in an electrical parameter or response value (e.g., conductance, current, voltage difference or resistance) of the coated versus uncoated SWCNT networks is analyzed. In a second embodiment, the network is doped with a transition element, such as Pd, Pt, Rh, Ir, Ru, Os and/or Au, and change in an electrical parameter value is again analyzed. The parameter change value depends monotonically, not necessarily linearly, upon concentration of the gas component.Type: GrantFiled: July 8, 2005Date of Patent: September 21, 2010Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA)Inventors: Jing Li, Meyya Meyyappan
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Patent number: 7790465Abstract: Methods, computer program products and apparatus determine a subject's risk of having or developing CHD using a calculated LDL particle risk number and/or a mathematical model of risk associated with LDL particles that adjusts concentrations of at least one of small and large LDL particle measurements to reflect predicted CHD risk.Type: GrantFiled: April 19, 2006Date of Patent: September 7, 2010Assignee: LipoScience, Inc.Inventor: James D. Otvos
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Patent number: 7792644Abstract: A frequency selective surface (FSS) and associated methods for modeling, analyzing and designing the FSS are disclosed. The FSS includes a pattern of conductive material formed on a substrate to form an array of resonance elements. At least one aspect of the frequency selective surface is determined by defining a frequency range including multiple frequency values, determining a frequency dependent permittivity across the frequency range for the substrate, determining a frequency dependent conductivity across the frequency range for the conductive material, and analyzing the frequency selective surface using a method of moments analysis at each of the multiple frequency values for an incident electromagnetic energy impinging on the frequency selective surface. The frequency dependent permittivity and the frequency dependent conductivity are included in the method of moments analysis.Type: GrantFiled: November 13, 2007Date of Patent: September 7, 2010Assignee: Battelle Energy Alliance, LLCInventors: Dale K. Kotter, David T. Rohrbaugh
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Publication number: 20100216043Abstract: A method of controlling a fuel cell system includes applying alternating current (AC) signals to an individual fuel cell. The AC signals have a plurality of different frequencies. A voltage across the individual fuel cell is determined at each of the plurality of different frequencies. An impedance characteristic of the individual fuel cell is determined based at least in part on the voltage across the individual fuel cell at each of the plurality of different frequencies. The individual fuel cell is controlled based at least in part on the impedance characteristic.Type: ApplicationFiled: February 25, 2009Publication date: August 26, 2010Inventors: Matthias Gottmann, David McKenzie, Patrick Muhl, Chad Pearson, James Daniel Smith
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Patent number: 7781729Abstract: A method for analyzing data from a mass spectrometer comprising obtaining calibrated continuum spectral data by processing raw spectral data; obtaining library spectral data which has been processed to form calibrated library data; and performing a least squares fit, preferably using matrix operations (equation 1), between the calibrated continuum spectral data and the calibrated library data to determine concentrations of components in a sample which generated the raw spectral data. A mass spectrometer system (FIG. 1) that operates in accordance with the method, a data library of transformed mass spectra, and a method for producing the data library.Type: GrantFiled: May 27, 2007Date of Patent: August 24, 2010Assignee: Cerno Bioscience LLCInventors: Yongdong Wang, Ming Gu
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Publication number: 20100208267Abstract: A system and a method for detecting the existence of a target substance, the system includes a laser with a broad spectral output and a detector for detecting an absorption spectrum of a laser beam from the laser. The method includes emitting a laser beam into the atmosphere using a laser light with a broad spectral output; measuring the absorption spectrum of said laser beam; comparing the absorption spectrum to known absorption spectrums for target substances using a detector; and detecting the existence of a target substance.Type: ApplicationFiled: February 13, 2009Publication date: August 19, 2010Inventors: Mark E. Rogers, Paul L. Thee, Richard A. Rosenthal, Paul D. Biernacki
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Patent number: 7778781Abstract: The present invention relates to automated generation of multi-dimensional structure activity and structure property relationships.Type: GrantFiled: June 24, 2008Date of Patent: August 17, 2010Assignee: F. Hoffmann-La-Roche AGInventors: Holger Fischer, Manfred Kansy
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Patent number: 7774185Abstract: The detection of protein sequence alignments firstly generates protein blocks having n successive C-alpha atoms from two protein sequences. A matrix of the distance of protein atoms from said C-alpha atoms for each block is then determined. A difference matrix is determined from respective distance matrices representing the differences between the protein blocks of the two protein structures. A Cellular Automaton (CA) model is generated in an initial configuration based upon the difference matrix, and evolved through at least one generation using predetermined rules. The rules determine which CA cells remain live and which are set to be dead.Type: GrantFiled: September 14, 2004Date of Patent: August 10, 2010Assignee: International Business Machines CorporationInventor: Deepak K Gangadhar
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Publication number: 20100198314Abstract: Methods and devices for providing computerized adjustment to therapy parameters using real time and retrospective data processing is provided. Embodiments include receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration, user notification and reminder of the predetermined time duration, time synchronizing the received respective data set, detecting one or more marked data from the one or more respective data set received, establishing one or more filtering criteria to filter of retrospective or historical data based on certain condition, performing automated data analysis based on the detected one or more marked data or the data achieving certain predetermined condition to generate a modification to a therapy profile, generating and modifying rules for profile modification, and providing the generated modification to the therapy profile for reporting and transmission.Type: ApplicationFiled: January 30, 2009Publication date: August 5, 2010Applicant: Abbott Diabetes Care, Inc.Inventor: Charles Wei
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Publication number: 20100191477Abstract: A particle behavior analysis system includes a calculation section that, regarding a decomposition portion decomposed in accordance with a decomposition method in a range to be analyzed, considers interaction force with another substance that acts on a particle and calculates behavior of the particle, while performing information communication with other devices; and an output processing section that switches output advisability of an analysis result obtained by the calculation section based on priority of the decomposition portion corresponding to the advisability of output processing of the analysis result.Type: ApplicationFiled: August 28, 2009Publication date: July 29, 2010Applicant: FUJI XEROX CO., LTD.Inventors: Tomohiro SEKO, Yoichi WATANABE, Hideki OKAMOTO, Nobuyuki HIROOKA, Ryosuke TAKAHASHI
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Publication number: 20100190075Abstract: A fuel cell system including a fuel cell stack having a plurality of fuel cells, the fuel cell stack including an anode supply manifold and an anode exhaust manifold, a first valve in fluid communication with at least one of the anode supply manifold and the anode exhaust manifold, wherein the first valve includes an inlet for receiving a fluid flow and an outlet for exhausting a fluid, a sensor for measuring at least a fluid pressure at the inlet and the outlet of the first valve, wherein the sensor generates a sensor signal representing the pressure measurement, and a processor for receiving the sensor signal, analyzing the sensor signal, and determining a composition of a fluid in the fuel cell system based upon the analysis of the sensor signal.Type: ApplicationFiled: January 28, 2009Publication date: July 29, 2010Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.Inventors: Patrick Frost, Daniel I. Harris, Manish Sinha, Gary M. Robb
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Publication number: 20100190073Abstract: A system and method for monitoring anode bleed trigger events and determining when to adjust a proactive bleed schedule in a fuel cell system. The system employs a bleed trigger monitor algorithm for monitoring proactive bleed and reactive bleeds that determines whether the reactive bleeds are caused by excess nitrogen in the anode. The algorithm monitors the number of reactive bleeds that are cause by nitrogen accumulation in the anode side of the fuel cell stack and changes the proactive bleed schedule in response thereto, if necessary.Type: ApplicationFiled: January 23, 2009Publication date: July 29, 2010Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.Inventors: SETH E. LERNER, Darrell W. Burleigh
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Patent number: 7765058Abstract: A method of driver training to improve fuel economy performance of a vehicle, the method including, receiving selected vehicle and driver operating data indicative of driving conditions and operator inputs captured during previous vehicle operation, processing the received selected vehicle and driver operating data, and generating driving recommendations to improve fuel economy performance based on the processed vehicle and driver operating data.Type: GrantFiled: November 20, 2006Date of Patent: July 27, 2010Assignee: Ford Global Technologies, LLCInventor: Jeff Doering
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Patent number: 7761239Abstract: A model of a particular biological state can be developed. The model may be used to determine if an unknown biological sample exhibits a particular biological state. This can be done by receiving either a biological sample or data associated with the biological sample. After the data is received, the data may be input into the model. In one embodiment, the acquisition of the data associated with the biological sample is performed at a first location and the imputing of the data into the model is performed at a second location different than the first location. Unless the data maps identically to the model, the data would have an inherent effect on the position of the particular clusters within the discriminatory pattern, if it is allowed to affect the model. The modeling software can keep track of the net effect on the model that each sample received has on the position of the model. If the model has drifted outside of a predetermined tolerance, the model can be updated.Type: GrantFiled: December 10, 2004Date of Patent: July 20, 2010Assignee: Correlogic Systems, Inc.Inventors: Tzong-Hao Chen, Ben A. Hitt, Peter J. Levine
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Patent number: 7754149Abstract: A clinical laboratory management system is described that includes an analyzer for analyzing a sample, and a management apparatus connected to the analyzer. The management apparatus includes (a) a storage configured for storing a result of an assay output from the analyzer, analyzer identification information for identifying whether or not the analyzer used for the assay has a dilution mode, and diluted sample identification information for identifying whether or not the sample used in the assay is a diluted sample; and (b) a controller configured for correcting the result when the analyzer used in the assay does not have a dilution mode, and the sample used in the assay is a diluted sample. Management apparatuses and recording media are also described.Type: GrantFiled: December 12, 2003Date of Patent: July 13, 2010Assignee: Sysmex CorporationInventor: Tomomi Sugiyama
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Patent number: 7756646Abstract: A method of predicting whether a peptide present in a biological sample will be detected by analysis with a mass spectrometer. The method uses at least one mass spectrometer to perform repeated analysis of a sample containing peptides from proteins with known amino acids. The method then generates a data set of peptides identified as contained within the sample by the repeated analysis. The method then calculates the probability that a specific peptide in the data set was detected in the repeated analysis. The method then creates a plurality of vectors, where each vector has a plurality of dimensions, and each dimension represents a property of one or more of the amino acids present in each peptide and adjacent peptides in the data set. Using these vectors, the method then generates an algorithm from the plurality of vectors and the calculated probabilities that specific peptides in the data set were detected in the repeated analysis.Type: GrantFiled: March 31, 2006Date of Patent: July 13, 2010Assignee: Battelle Memorial InstituteInventors: Lars Kangas, Richard D. Smith, Konstantinos Petritis