Abstract: LC/MS data generated by an LC/MS system is analyzed to determine groupings of ions associated with originating molecules. Ions are grouped initially according to retention time, for example, using retention time or chromatographic peaks in mass chromatograms. After initial groupings are determined based on retention time, ion peak shapes are compared to determine whether ions should be excluded. Ions having peak shapes not matching other ions, or alternatively a reference peak shape, are excluded from the group.

Abstract: Gas-selective electrodes in liquid analyzing devices have a characteristic curve K with a linear portion L and a non-linear portion NL. In the non-linear portion NL, the characteristic previously could only be estimated so that determinations of the concentration were rather inexact. According to the present application, the electrode is rinsed with an acid and the zero point voltage UN at the electrode is determined during the rinsing. Using the zero point voltage UN, the non-linear portion NL of the characteristic K is determined with high precision so that even low concentrations c can be determined with great accuracy.

Abstract: Methods for using modified single wall carbon nanotubes (“SWCNTs”) to detect presence and/or concentration of a gas component, such as a halogen (e.g., Cl2), hydrogen halides (e.g., HCl), a hydrocarbon (e.g., CnH2n+2), an alcohol, an aldehyde or a ketone, to which an unmodified SWCNT is substantially non-reactive. In a first embodiment, a connected network of SWCNTs is coated with a selected polymer, such as chlorosulfonated polyethylene, hydroxypropyl cellulose, polystyrene and/or polyvinylalcohol, and change in an electrical parameter or response value (e.g., conductance, current, voltage difference or resistance) of the coated versus uncoated SWCNT networks is analyzed. In a second embodiment, the network is doped with a transition element, such as Pd, Pt, Rh, Ir, Ru, Os and/or Au, and change in an electrical parameter value is again analyzed. The parameter change value depends monotonically, not necessarily linearly, upon concentration of the gas component.

Abstract: A material is laced with Radio Frequency Identification (RFID) tags at a known concentration of RFID tags per unit of material. Subsequently, if an interrogation of the RFID tags reveals a reduced concentration of RFID tags in the material, then a conclusion is drawn that the material has been diluted.

Abstract: Methods, computer program products and apparatus determine a subject's risk of having or developing CHD using a calculated LDL particle risk number and/or a mathematical model of risk associated with LDL particles that adjusts concentrations of at least one of small and large LDL particle measurements to reflect predicted CHD risk.

Abstract: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals, obtaining reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals, calculating the calibration characteristics using the reference glucose values and corresponding glucose monitor data to regress the obtained glucose monitor data, and calibrating the obtained glucose monitor data using the calibration characteristics. In additional embodiments, calculation of the calibration characteristics includes linear regression and, in particular embodiments, least squares linear regression. Alternatively, calculation of the calibration characteristics includes non-linear regression. Data integrity may be verified and the data may be filtered.

Abstract: A method for analyzing data from a mass spectrometer comprising obtaining calibrated continuum spectral data by processing raw spectral data; obtaining library spectral data which has been processed to form calibrated library data; and performing a least squares fit, preferably using matrix operations (equation 1), between the calibrated continuum spectral data and the calibrated library data to determine concentrations of components in a sample which generated the raw spectral data. A mass spectrometer system (FIG. 1) that operates in accordance with the method, a data library of transformed mass spectra, and a method for producing the data library.

Abstract: The present invention relates to a system for determining particle transmittance Tx of a filter for use with a particle detection system to provide a filter warning for aspirated particle detection systems by detecting a level of first particles having a size indicative of smoke particles and which pass through the detection system; determining an integrated smoke hours value by integrating the detected level of first particles over time; estimating the smoke particle transmittance Tx of the filter by applying a predetermined weighting operation to the integrated smoke hours value. An empirical measure of a filter's particle transmittance Tx, due to at least first particles having a size indicative of smoke particles may be achieved by way of integrating a level of such first particles passing through a particle detection system over time to determine the proportion of smoke particles arrested by a filter, “integrated smoke hours”.

Abstract: A substance analyzer utilizing Prompt Gamma Neutron Activation Analysis for identifying characteristics of a substance and method of manufacturing the same are disclosed. The analyzer is small enough to be portable and to allow its use in many applications where current analyzers cannot be utilized. The analyzer uses a neutron radiation source and a gamma-ray detector to activate the sample material and detect the prompt gamma rays emitted by the sample material. A novel housing for such an analyzer and method for making the housing are also described. Novel methods of operating such an analyzer including via a communications network are also disclosed. Also disclosed are data analysis methods that improve the accuracy and sensitivity of the results of such material analysis.

Abstract: A method of predicting whether a peptide present in a biological sample will be detected by analysis with a mass spectrometer. The method uses at least one mass spectrometer to perform repeated analysis of a sample containing peptides from proteins with known amino acids. The method then generates a data set of peptides identified as contained within the sample by the repeated analysis. The method then calculates the probability that a specific peptide in the data set was detected in the repeated analysis. The method then creates a plurality of vectors, where each vector has a plurality of dimensions, and each dimension represents a property of one or more of the amino acids present in each peptide and adjacent peptides in the data set. Using these vectors, the method then generates an algorithm from the plurality of vectors and the calculated probabilities that specific peptides in the data set were detected in the repeated analysis.

Abstract: The present invention can be generally described as a vapor detection instrument testing system and testing process. This testing system integrates a computing system loaded with testing software, and a test-substance generating device. The present device is portable and provides a user with the ability to perform vapor detection instrument testing at the field side of the vapor detection instrument. The portability of the vapor detection instrument testing system results in more frequent instrument testing and less detection instrument down time.

Abstract: Systems and methods for assessing and optimizing energy use and environmental impact can be designed to receive energy consumption and emission data from one or more energy consumption sources of a facility over a network. The data can be transformed into a database format that can be processed and analyzed. The data can be validated according to predefined validation rules. The data can be aggregated according to predefined time intervals and stored in memory. The data can be used to generate a report to a user, for example, via a user interface.

Abstract: A NOx estimation system includes an operating mode determination module that determines an operating mode of an engine, and an emission prediction module. The emission prediction module estimates NOx emission based on the operating mode, a plurality of sensed parameters, and a map. The map correlates the plurality of sensed parameters to the NOx emission based on the operating mode.

Abstract: A drug delivery presentation is disclosed herein. The drug delivery presentation includes a display for showing a concentration of at least two different types of drugs including a first drug and a second drug for a subject, and also for showing a coordinate system for a variable first drug concentration and a variable second drug concentration. The drug delivery presentation also includes an optimal therapy mixture area presented on a coordinate system comprising a first border section determining a minimum concentration mixture for the first drug and the second drug. The optimal therapy mixture area further comprising a second border section determining a maximum concentration mixture for the first drug and the second drug. An arrangement for a drug delivery presentation is also disclosed.

Abstract: A computer facilitated method of requesting a spectral analysis of a sample having an unknown concentration or purity, performing an energy absorption analysis of the sample to obtain spectral data regarding the analysis and comparing the spectral data to stored spectral data regarding the analyses of the samples having a predetermined concentration and purity to determine the concentration or purity of the sample having an unknown concentration or purity. The spectral analysis is performed on site where the sample is prepared or administered using a portable analytical apparatus and provides a real time report of the concentration or purity of the sample. The apparatus requires only a small sample size.

Abstract: The present invention relates to a method for measuring the concentration of a particular component in a blood sample containing blood cells based on a variable correlated with the concentration of the particular component. In the present invention, a concentration (S) in blood plasma obtained by removing blood cell components from the blood sample, a concentration (DI) in the blood sample computed by a differential method and a concentration (EP) in the blood sample computed by an equilibrium point method are expressed by a relational expression which is unrelated to the proportion of the blood cell components in the blood sample, and the concentration of the particular component is computed by using the relational expression.

Abstract: A computer implemented method, apparatus, and computer program product for generating olfactory cohorts. Olfactory data is received from a set of chemical sensors. The olfactory data describes a set of olfactory patterns for an air sample. The olfactory data is processed to identify attributes of particles in the air sample and generate digital olfactory data. The digital olfactory data comprises metadata describing the attributes of the particles in the air sample to form digital olfactory data. A set of olfactory cohorts is generated using the attributes in the digital olfactory data.

Abstract: Method and sensing module for sensing pollution of outside air. The sensing module (1) comprises an electro chemical sensing element (3), and a processor (2). A sensing module output signal is provided based on the measurement signal and a baseline signal level. The baseline signal level is adapted depending on two threshold levels (13-15). A pollution concentration value is determined from the measurement signal and a classification level of air pollution is provided as sensing module output signal. A classification level is determined using a plurality of classification threshold values and the pollution concentration values. The plurality of classification threshold values are dynamically adjustable.

Abstract: Several full-spectrum imaging techniques have been introduced in recent years that promise to provide rapid and comprehensive chemical characterization of complex samples. One of the remaining obstacles to adopting these techniques for routine use is the difficulty of reducing the vast quantities of raw spectral data to meaningful chemical information. Multivariate factor analysis techniques, such as Principal Component Analysis and Alternating Least Squares-based Multivariate Curve Resolution, have proven effective for extracting the essential chemical information from high dimensional spectral image data sets into a limited number of components that describe the spectral characteristics and spatial distributions of the chemical species comprising the sample. There are many cases, however, in which those constraints are not effective and where alternative approaches may provide new analytical insights.

Abstract: The invention concerns a method and an apparatus for the quantitative determination of the concentration of fluorophores of at least one substance in a sample. A constant portion of the reference light of a reference light wave length (?r) emitted by a reference light source (28) is coupled in by an optical element (REM) in the direction of a receiving element (38). A first measured value is detected which corresponds to the portion of the reference light coupled in which is incident on the receiving element (38). The sample is irradiated with the excitation light of an excitation wave length (?ex) emitted by an excitation light source (26). A second measured valued is detected which corresponds to the portion of the fluorescent light of an emission wave length (?em) emitted by the sample which is incident on the receiving element (38). The ratio (Emes2/Es2) of the second measured value (Emes2) to the first measured value (Es2) is determined.

Abstract: A method for quantitating a substance to be measured according to which a substance to be measured is quantitated is characterized by including: a database storing step of storing a database with which a relative calibration curve is registered; an internal standard substance measuring step of measuring an internal standard substance having a known concentration so that a mass spectrum of the internal standard substance is gained; an absolute value calculating step of calculating the peak area or the height of an internal standard substance by preparing a chromatogram on the basis of the mass spectrum of the internal standard substance; a substance to be measured measuring step of gaining a mass spectrum of the substance to be measured by measuring the substance to be measured; a measured value calculating step of calculating the peak area or the height of the substance to be measured by preparing a chromatogram on the basis of the mass spectrum of the substance to be measured; and a concentration of a substa

Abstract: A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; determining a pattern value for the sequence responsive to said identifying; and determining said aggregation rate data by determining a weighted combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence.

Abstract: A sensor is provided for the detection of a marker in a sample in which the sensor includes a high frequency 500 kHz-1 GHz piezoelectric ceramic resonator, with the system measuring resonant frequency change. In one embodiment, the piezoelectric sensor operates in the thickness extensional (TE) mode, with the high frequency and TE mode permitting fabrication of an exceptionally small size sensor capable of being arrayed in a handheld unit.

Abstract: A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device comprises a separation unit for separating a component included in a sample, a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation. The chromatograph analyzing device also includes a storage device for saving a plurality of sample waveforms having overlapped peaks of the chromatograph and methods for separating each of the sample wavefroms so that the plurality of sample waveforms are associated with the methods.

Abstract: A method and system of physically solving the charge, mass, and current density functions of excited-state atoms and atomic ions using Maxwell's equations and computing and rendering the nature of excited-state electrons using the solutions. The results can be displayed on visual or graphical media. The display can be static or dynamic such that electron spin and rotation motion can be displayed in an embodiment. The displayed information is useful to anticipate reactivity and physical properties. The insight into the nature of excited-state electrons can permit the solution and display of those of other atoms and atomic ions and provide utility to anticipate their reactivity and physical properties as well as spectral absorption and emission to lead to new optical materials and light sources.

Abstract: The present invention relates to a realistic service and system using a five senses integrated interface, and more particularly, to an apparatus and method for encoding the five senses and a system and method for providing realistic service using a five senses integrated interface, to allow a user to select a product to sensorially experience through an integrated interface in a remote location, which includes a integration recognizer detecting data selected by the user and recognizing an object, and transmitting five senses data of the object through a network, a five senses data analyzer receiving a five senses data packet including the five senses data of the object through the network, and extracting and analyzing the five senses data packet in terms of data on each of the five senses, and a five senses integration representer representing five senses using the data on each of the five senses.

Abstract: A mass spectrometer includes an ion detector, an analog-to-digital (A/D) converter, and a decimator. The analog-to-digital (A/D) converter is configured to receive and sample an analog signal from the ion detector thereby providing a first plurality of samples at a first rate. The decimator is configured to receive the first plurality of samples and to transmit, at a second rate, a second plurality of samples that are based on the first plurality of samples. The decimator is further configured to dynamically adjust the second rate so that memory requirements for the mass spectrometer are reduced.

Abstract: A method and apparatus for interfacing a plurality of gas measurement systems, including a mainstream and a sidestream gas measurement system, to a host system via an interface unit. The present invention also pertains to a sidestream gas measurement system that output signals emulating the signals output by a mainstream gas measurement system or portion thereof, so that the sidestream gas measurement system can seamlessly communicate with a host system configured to communicate with a mainstream gas measurement system or a portion thereof.

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination area, in which a magnetic field is generated which has a first part-region having a relatively low magnetic field strength and a second part-region having a relatively high magnetic field strength. The position of the two part-regions is changed, as a result of which the magnetization in the examination area changes, and real measured values which depend on the change in magnetization are recorded. A dependence distribution which depends on a spatial distribution of magnetic particles is then determined such that a sum which comprises as summands a) the difference of the real measured values from fictitious measured values which are determined by applying a transfer function to the dependence distribution, and b) the product of a regularization parameter and of a regularization value which is determined by applying the regularization functional to the dependence distribution, is minimized.

Abstract: A System and Method for Gas Recognition by Analysis of Bispectrum Functions is based on the Higher-Order Spectral analysis of time series measurements of resistance fluctuations in Metal Oxide Semiconductor (MOS) gas sensors, such as Taguchi-type sensors. A two-dimensional contour plot module of the bispectrum function is treated as a pattern. These patterns include information about the analyte(s) whereby characteristics of the gas can be identified.

Abstract: A method for processing KStore sensors for use by a KEngine in a KStore system to process a K includes providing a stream of particles, instantiating a KStore sensor structure, identifying particles to be included in a sensor set and processing said identified particles. The KStore sensor structure can provide a correspondence between a particle and a sensor K node. Furthermore, the KStore sensor structure can be a list of K nodes, an indexed array or a hash table.

Abstract: Provided is an optical detecting method including setting an amplification time for amplifying an electrical signal converted from light generated in reaction chambers, changing the amplification time if a value obtained by amplifying the electrical signal for the amplification time does is not within a predetermined range of values, and amplifying for the changed amplification time and outputting the amplified electrical signal.

Abstract: The present invention relates to a NOx sensor and a calculating method of total NOx concentration using the same, and more particularly, to a NOx sensor which has improved sensitivity to NO and NO2 and simply calculates NO, NO2 and total NOx concentration, and a calculating method of total NOx concentration using the same. The NOx sensor of the present invention comprises an oxygen ion conductive solid electrolyte 10; an oxide sensing electrode 20 formed at the oxygen ion conductive solid electrolyte 10; a noble metal electrode 30; and a lead line 40 connected to each of the oxygen ion conductive solid electrolyte 10 or the oxide sensing electrode 20 or the noble metal electrode 30, wherein the oxygen ion conductive solid electrolyte 10 and the oxide sensing electrode 20 form at least two interfaces.

Abstract: A system for predicting a source location and release rate of a hazardous substance uses the basic knowledge of meteorological information (wind speed, direction, and stability) and two or more concentration measurements of the chemical released. Horizontal dispersion information obtained from surface meteorological data at sensor locations are used to narrow the search domain for the release location, reducing the computational cost. Each of the possible release locations in the search domain and possible release rates are evaluated in a process that predicts a concentration measurement at a sensor, based on a predicted location and release rate. The location and release rate that results in a least error when compared to an actual concentration measurement at the sensor are chosen as the source of the chemical and the release rate from the source.

Abstract: A gas monitoring apparatus capable of real-time detection of a kind of chemical warfare agent, namely diphenylcyanoarsine (DC) and/or diphenylchloroarsine (DA). Atmospheric pressure chemical ionization mass spectrometry is carried out in the positive ionization mode, the total amount of DC and DA is determined from the intensity of an ion common to DC and DA, the DC concentration is determined from the intensity of an ion specific to DC, and the difference between them is regarded as the DA concentration.

Abstract: A recycling method that can be used by an OEM products company or other entity to obtain recovered raw materials for use in its manufacturing operations in a manner that helps ensure the quality and traceability of the recovered raw materials. The process involves first collecting the material from one or more sources, then determining suitability of the material for processing using a series of qualifying tests separated into a two-phase review, wherein each of the qualifying tests is carried out using a composition profile for the material. The first phase of the review utilizes a source composition profile that describes salient features of the material so that it can be reviewed for suitability for processing and end uses as well as for regulatory compliance. The second phase involves similar reviews based on an analytical composition profile that is determined by physical analysis of the material.

Abstract: Techniques, apparatus and systems for detecting particles such as muons. In one implementation, a monitoring system has a cosmic ray-produced charged particle tracker with a plurality of drift cells. The drift cells, which can be for example aluminum drift tubes, can be arranged at least above and below a volume to be scanned to thereby track incoming and outgoing charged particles, such as cosmic ray-produced muons, whilst also detecting gamma rays. The system can selectively detect devices or materials, such as iron, lead, gold and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can also detect any radioactive sources occupying the volume from gamma rays emitted therefrom. If necessary, the drift tubes can be sealed to eliminate the need for a gas handling system. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.

Abstract: Techniques are disclosed for reducing scan times in mass spectral tissue imaging studies. According to a first technique, a tissue imaging boundary is defined that closely approximates the edges of a tissue sample. According to a second technique, a low-resolution scan is performed to identify one or more areas of interest within the tissue sample, and the identified areas of interest are subsequently scanned at higher resolution.

Abstract: Method for managing a response to a triggering event in connection with a fugitive emissions monitor of a component. In one implementation, the method may include determining whether an input is a triggering event. If the input is a triggering event, then a message regarding the triggering event and one or more actions to remedy the triggering event may be displayed. The method may further include displaying one or more queries to confirm that the actions have been completed.

Abstract: The present invention is designed to efficiently calculate isotopic distribution in order to simulate mass spectra data for any chemical compound of interest. The simulated spectra considers the various isotopes of the compound based upon a probability calculation that takes into consideration the natural abundance of each isotope of individual elements of the compound. The probability calculation generates a relative probability associated with each isotope species of the subject compound. The simulated spectra are displayed on an x-y coordinate illustrating the calculated formula weight on the abscissa (x-axis) and the intensity of the specific species on the ordinate (y-axis). This theoretical data is then compared to experimental data taken from a mass spectrometer in order to identify the chemical compound at issue.

Abstract: Analysis of a group of proteomic samples is facilitated. According to an example embodiment of the present invention, ion mass spectrometry data is collected for a group of samples. For each sample, at least one grouping of ions is identified and used to generate another estimated grouping of ions relating to the sample. Using these groupings, characteristics of the sample are detected.

Abstract: This invention describes a method of reducing the effect of interfering compounds in a bodily fluid when measuring an analyte using an electrochemical sensor. In particular, the present method is applicable to electrochemical sensors where the sensor includes a substrate, first and second working electrodes, and a reference electrode and either the first and second or only the second working electrode include regions which are bare of reagent. In this invention, an algorithm is described with mathematically corrects for the interference effect using the test strip embodiments of the present invention.

Abstract: Method and system for providing a subscription based replenishment transaction of consumable items such as glucose test strips, lancets, and medication, such as insulin, including a data network, a user terminal operatively coupled to the data network, the user terminal configured to receive and transmit data over the data network, and a server terminal operatively coupled to the data network, the server terminal configured to receive from the user terminal a request for establishing an account associated with a consumable item, receive from the user terminal one or more predetermined parameters associated with the account, and generate the account based on the one or more predetermined parameters, where the one or more predetermined parameters include a user specified consumable replenishment level received from the user terminal is disclosed.

Abstract: Systems and methods for reducing background noise in a mass spectrum. The method includes the following steps of: (a) obtaining an original mass spectrum; (b) determining a noise mass spectrum corresponding to background noise in the original mass spectrum; and (c) determining a corrected mass spectrum by subtracting the noise mass spectrum from the original mass spectrum. Step (b) of the method may include the steps of: A) effecting a transformation of the original mass spectrum into the frequency domain to obtain an original frequency spectrum; B) identifying at least one dominant frequency in the original frequency spectrum; C) generating a noise frequency spectrum by selectively filtering for said dominant frequencies; and D) determining the noise mass spectrum by effecting a transformation of the noise frequency spectrum into the mass domain.

Abstract: A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device comprises a separation unit for separating a component included in a sample, and a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation.

Abstract: A method includes: accumulating ions having a plurality of m/z values in an ion trap during a time interval; deriving from the accumulated ions a respective intensity value for each of the m/z values; and adjusting each of the intensity values as a function of the time needed by the ion trap to begin collecting ions with the corresponding m/z value. According to a different aspect, an apparatus includes a first portion with an ion trap, and a second portion. The second portion causes the ion trap to accumulate ions with a plurality of m/z values during a time interval, derives from the accumulated ions in the ion trap a respective intensity value for each of the m/z values, and adjusts each of the intensity values as a function of the time needed by the ion trap to begin collecting ions with the corresponding m/z value.

Abstract: This is a device for analyzing the quantity of organic compounds existing in a liquid, such as ultrapure water, at the outlet from a purification device including in series filter means (1), oxidation means (2) and polishing means (3), further including means for measuring the resistivity of water to determine the purity thereof, characterized in that it includes only one resistivity measuring cell (4) and in that the outlet points of said filter means (1) and said oxidation means (2) are connected to said resistivity measuring cell (4) by pipes provided with an analysis valve (6) and/or check valves (5) selectively enabling circulation of said liquid within them.

Abstract: In general, the invention relates to gas sensing techniques as such, but more specifically, to a sensor structure that comprises a buried electrode structure in the sensor layers, the structure being arranged to be applicable in the related devices and/or measurements. The invention relates also to a measurement method of sensor resistance, which method comprises a step of utilisation having a bias voltage or a grounding applied to the buried electrode.

Abstract: The present teachings relate to a method of filtering mass spectrometer data using a variable filter window. The width of the window can depend on the mass itself and the mass defects for a family of compounds. The teachings can be used with a plurality of compounds including but not limited to peptides and can be utilized on a brood range of mass spectrometers.

Abstract: A first frequency of electromagnetic radiation and a second frequency of electromagnetic radiation are received at a detector. The first and second frequencies of electromagnetic radiation are transmitted through a medium within a frequency range of approximately 0.1 TeraHertz to approximately 10 TeraHertz. Signals are generated that are proportional to the transmittance of the frequencies of electromagnetic radiation through the medium. A ratio of the of the signals is formed, and one or more of a relative humidity, an absolute humidity, and a water vapor concentration of the medium are calculated as a function of a temperature of the medium, the ratio, and a set of functional parameters associated with the temperature of the medium.