Quantitative Determination (e.g., Mass, Concentration, Density) Patents (Class 702/23)
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Publication number: 20110251799Abstract: The present invention accepts attribute information of evaluation subject parts, and judgment standards of parts category by a data acquiring unit; acquires attribute information and chemical substance information relating to a part already inspected; categorizes the relevant attribute information and the relevant chemical substance information to a part group having attribute information of the evaluation subject parts, and a part group not having it; carries out calculation of statistic values of the content rate of a specified chemical substance in each of the parts groups, comparison between difference of said statistic values in each of the parts groups and the relevant judgment standards, and extraction of said attribute information; extracts attribute information and chemical substance information of said parts already inspected, coincident with all of attribute information extracted; and calculates the statistic value such as an average value relating to the content rate of the chemical substance of tType: ApplicationFiled: February 7, 2011Publication date: October 13, 2011Inventor: Masataka TANAKA
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Patent number: 8036861Abstract: The present invention relates to methods and means for determining the replication rate of a viral population. More specifically, the invention provides methods and means for determining the replication rate of a viral population by performing a linear regression on signal data generated by cells infected with dilutions of the viral population. The methods are useful for monitoring the progression of diseases associated with viruses, identifying effective drug regimens for the treatment of viral infections, and identifying and determining the biological effectiveness of potential therapeutic compounds.Type: GrantFiled: October 13, 2006Date of Patent: October 11, 2011Assignee: Tibotec PharmaceuticalsInventors: Laurence Tatiana Rimsky, Herwig Gaston Emiel Van Marck, Marie-Pierre T. M. M. G. De Bethune, Lee Terry Bacheler
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Publication number: 20110246087Abstract: The present invention is directed to a method for automatic selection of colorants and flakes to produce one or more matching formulas to match color and appearance of a target coating containing flakes. The present invention is further directed to a system for automatic selection of colorants and flakes for producing one or more matching formulas to match color and appearance of a target coating.Type: ApplicationFiled: February 21, 2008Publication date: October 6, 2011Inventors: Arun Prakash, Judith Elaine Obetz
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Patent number: 8032321Abstract: A biosensor system determines the presence and/or concentration of an analyte in a sample using one or more calibrated correlation equations. The analysis may be electrochemical, optical, or a combination thereof. The biosensor system may be implemented using a measurement device and a sensor strip. The measurement device applies test signals to a multi-layered encoding area of the sensor strip. Calibration information is determined from the patterns generated by the interaction of the test signals with the multi-layered encoding area.Type: GrantFiled: July 15, 2008Date of Patent: October 4, 2011Assignee: Bayer Healthcare LLCInventor: Weiping Zhong
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Patent number: 8032311Abstract: A method for characterizing a desired property of a fluid downhole is described. In some non-limiting examples, the method comprises receiving an input signal representing sound speed of a fluid downhole, processing the input signal using a correlation equation expressing the desired property in terms of at least sound speed to produce an output signal representing the desired property, and outputting the output signal. In some examples, the correlation equation is derived through a chemometric analysis of a training data set, the training data set comprises a plurality of input values and a plurality of output values derived from said input values, between the desired fluid property and the first measured property, and the output values are calculated from the input values using a series of correlation equations. In at least one example, the desired property is gas oil ratio. In another example, the desired property is gas brine ratio.Type: GrantFiled: May 22, 2008Date of Patent: October 4, 2011Assignee: Baker Hughes IncorporatedInventor: Rocco DiFoggio
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Patent number: 8027814Abstract: The present invention provides methods for assessing a condition in an individual by analyzing a cerebrospinal fluid sample from the individual, for example, by spectroscopy. Further, the invention provides methods for determining an amount of blood in the cerebrospinal fluid sample; methods for determining concentrations of analytes in the cerebrospinal fluid sample; methods for determining a length of time the blood has been in the cerebrospinal fluid sample; and methods for rapidly obtaining a differential diagnosis between conditions indicated by blood in the cerebral spinal fluid. Moreover, the present invention provides instruments capable of rapidly assessing a condition in and individual by point-of-care analysis of a cerebral fluid sample from an individual.Type: GrantFiled: August 1, 2005Date of Patent: September 27, 2011Assignee: University of CincinnatiInventors: Fred R. Beyette, Jr., Joseph F. Clark, Chad J. Morgan, James J. Caffery, Jr., Prashant Bhadri, Gail Pyne-Geithman, Anindya Majumder
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Patent number: 8016997Abstract: A method is provided for determining analyte concentrations, for example glucose concentrations, that utilizes a dynamic determination of the appropriate time for making a glucose measurement, for example when a current versus time curve substantially conforms to a Cottrell decay, or when the current is established in a plateau region. Dynamic determination of the time to take the measurement allows each strip to operate in the shortest appropriate time frame, thereby avoiding using an average measurement time that may be longer than necessary for some strips and too short for others.Type: GrantFiled: January 12, 2010Date of Patent: September 13, 2011Assignee: Agamatrix, Inc.Inventors: Steven Diamond, Ian Harding, Sridhar G. Iyengar, Baoguo Wei
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Patent number: 8019556Abstract: A method and system for nuclear substance revealing using muon detection technique is presented. In some aspects, naturally occurred muons are selected from the flow of charged particles. Muon coordinate and incidence angle measured above and below the interrogated volume can be used for the decision making on the presence of nuclear substance inside the volume. The system is adapted for performing measurements on moving objects such as moving trucks. A combination of the nuclear substance detection system with an explosive sensing system is presented.Type: GrantFiled: August 11, 2009Date of Patent: September 13, 2011Inventors: Isaac Shpantzer, Yaakov Achiam, Nadejda Reingand
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Publication number: 20110218739Abstract: An apparatus for measuring pungency of red pepper powder including: a near infrared measuring unit for measuring a spectrum of a reference material or a near infrared spectrum of red pepper powder that is an object of measurement according to a control signal using a near infrared sensor; a reference spectrum measuring unit for enabling the near infrared measuring unit to measure the spectrum of the reference material; a red pepper powder injecting unit for injecting a sample of the red pepper powder that is the object of measurement; a red pepper powder height equalizing unit for equalizing heights of the red pepper powder injected through the red pepper powder injecting unit in order to increase the accuracy of measurement; a red pepper powder transferring unit for transferring the red pepper powder that is the object of measurement via a transfer belt; a red pepper powder ejecting unit for ejecting the completely measured sample of the red pepper powder; a display unit for displaying an operation state orType: ApplicationFiled: July 1, 2010Publication date: September 8, 2011Applicant: RURAL DEVELOPMENT ADMINISTRATIONInventors: Chang Yeun Mo, Kang Jin Lee, Jae Ryong Son, Hyun Dong Lee, Jai Gyu Kim, Sukwon Kang, Gil Mo Yang
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Patent number: 8014962Abstract: A method for analyzing a multi-channel chromatogram is realized for accurately resolving overlapping peaks on a multi-channel chromatogram to permit analysis of the composition of a sample. First, components of overlapping peaks are specified. A data matrix Dij is determined, and compressed in the wavelength direction to obtain a data matrix vector Di. Next, the two-dimensional data is deconvoluted, final standard deviation s0 is registered, and the deconvoluted two-dimensional data is reconvoluted to a retention intensity matrix. A quantitative spectral intensity matrix is computed, components are identified, and the identified components are quantified. Subsequently, an eigenvalue problem is solved, and the number n of components is estimated. The deconvolution and computation of the eigenvalue problem are iteratively executed until the peaks are isolated. Then, elution profiles are calculated, the components are identified, and the identified components are quantified.Type: GrantFiled: March 12, 2008Date of Patent: September 6, 2011Assignee: Hitachi, Ltd.Inventors: Masahito Ito, Kisaburo Deguchi
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Publication number: 20110213565Abstract: Techniques for sensing chemicals in aqueous environments, and systems configured for sensing chemicals in aqueous environments are provided. More particularly, techniques and systems for detecting a presence or absence of aromatic chemicals in aqueous environments are provided. An example may include receiving emitted light from a first port of an optical circulator, reflecting at least a portion of the received emitted light to produce reflected light, and transmitting the reflected light from the second port of the optical circulator. The reflected light may be produced, at least in part, by an interaction of chemicals and an array of photonic silica of the second port.Type: ApplicationFiled: March 1, 2010Publication date: September 1, 2011Inventor: Angele Sjong
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Publication number: 20110213564Abstract: This document discusses, among other things, a method for verifying a result of a test. The method includes providing a plurality of codes that are indicative of a first result of a test. A first test is then performed on a material. A first code of the plurality of codes is output when the first test produces the first result.Type: ApplicationFiled: February 26, 2010Publication date: September 1, 2011Inventor: Tom L. Henke
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Patent number: 8008025Abstract: The present invention provides methods for diagnosing neurodegenerative disease, such as Alzheimer's Disease, Parkinson's Disease, and dementia with Lewy body disease by detecting a pattern of gene product expression in a cerebrospinal fluid sample and comparing the pattern of gene product expression from the sample to a library of gene product expression pattern known to be indicative of the presence or absence of a neurodegenerative disease. The methods also provide for monitoring neurodegenerative disease progression and assessing the effects of therapeutic treatment. Also provided are kits, systems and devices for practicing the subject methods.Type: GrantFiled: October 28, 2008Date of Patent: August 30, 2011Assignee: University of WashingtonInventor: Jing Zhang
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Patent number: 8010306Abstract: A method for obtaining at least one calibration filter for a Mass Spectrometry (MS) instrument system. Measured isotope peak cluster data in a mass spectral range is obtained for a given calibration standard. Relative isotope abundances and actual mass locations of isotopes corresponding thereto are calculated for the given calibration standard. Mass spectral target peak shape functions centered within respective mass spectral ranges are specified. Convolution operations are performed between the calculated relative isotope abundances and the mass spectral target peak shape functions to form calculated isotope peak cluster data. A deconvolution operation is performed between the measured isotope peak cluster data and the calculated isotope peak cluster data after the convolution operations to obtain the at least one calibration filter. Provisions are made for normalizing peak widths, combining internal and external calibration, and using selected measured peaks as standards.Type: GrantFiled: February 16, 2009Date of Patent: August 30, 2011Assignee: Cerno Bioscience LLCInventors: Yongdong Wang, Ming Gu
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Patent number: 8010312Abstract: A measuring system includes at least one temperature sensor placed at a temperature measuring point, to deliver at least one temperature measurement signal influenced by the local temperature of a medium to be measured. At least one pressure sensor is placed at a pressure measuring point, and delivers at least one pressure measurement signal influenced by the local pressure in the medium. At least one flow sensor is placed at a flow measuring point, and delivers at least one flow measurement signal influenced by the local flow parameter. Measuring electronics calculates, based on the temperature measurement signal, the pressure measurement signal, and the flow measurement signal, at least one density measured-value, representing, instantaneously, a local density of the medium at a virtual density measuring point, the virtual density measuring point being spaced from the pressure measuring point and/or from the temperature measuring point along the flow axis.Type: GrantFiled: June 30, 2008Date of Patent: August 30, 2011Assignee: Endress + Hauser Flowtec AGInventor: Rainer Höcker
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Publication number: 20110202288Abstract: An initial concentration of the residual concentration of a causative substance contained in an insulating oil is compared with a reference value. The causative substance reacts with a conductor forming a winding of an oil-filled electrical device to generate an electrically conductive compound. The reference value is defined as a value for determining whether a main determinant that determines the lifetime of the oil-filled electrical device is generation of the electrically conductive compound or degradation of insulating paper. Based on the initial concentration of the causative substance and the reference value, the lifetime of the oil-filled electrical device is assessed.Type: ApplicationFiled: July 7, 2010Publication date: August 18, 2011Applicant: Mitsubishi Electric CorporationInventors: Fukutaro Kato, Eiichi Nagao, Tsuyoshi Amimoto, Satoru Toyama, Kota Mizuno
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Publication number: 20110202287Abstract: Systems and methods are used to predict intensities of a saturated peak using a peak predictor. A set of data is selected from the plurality of intensity measurements that includes a saturated peak. Confidence values are assigned to each data point in the set of data producing a plurality of confidence value weighted data points. A peak predictor is selected. The peak predictor is applied to the plurality of confidence value weighted data points of the saturated peak producing predicted intensities for the saturated peak. The confidence values can include system confidence values, predictor confidence values, or a combination of system confidence values and predictor confidence values. The peak predictor can be a theoretical model, a dynamic model, an artificial neural network, or an analytical function representing a best fit of a plurality of probability density functions to a first set of measured data that includes a representative non-saturated peak.Type: ApplicationFiled: February 12, 2010Publication date: August 18, 2011Inventor: Gordana Ivosev
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Patent number: 8000903Abstract: Methods for using modified single wall carbon nanotubes (“SWCNTs”) to detect presence and/or concentration of a gas component, such as a halogen (e.g., Cl2), hydrogen halides (e.g., HCl), a hydrocarbon (e.g., CnH2n+2), an alcohol, an aldehyde or a ketone, to which an unmodified SWCNT is substantially non-reactive. In a first embodiment, a connected network of SWCNTs is coated with a selected polymer, such as chlorosulfonated polyethylene, hydroxypropyl cellulose, polystyrene and/or polyvinylalcohol, and change in an electrical parameter or response value (e.g., conductance, current, voltage difference or resistance) of the coated versus uncoated SWCNT networks is analyzed. In a second embodiment, the network is doped with a transition element, such as Pd, Pt, Rh, Ir, Ru, Os and/or Au, and change in an electrical parameter value is again analyzed. The parameter change value depends monotonically, not necessarily linearly, upon concentration of the gas component.Type: GrantFiled: April 28, 2006Date of Patent: August 16, 2011Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Asministration (NASA)Inventor: Jing Li
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Patent number: 7996158Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.Type: GrantFiled: May 14, 2008Date of Patent: August 9, 2011Assignee: Abbott Diabetes Care Inc.Inventors: Gary Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John C. Mazza, Benjamin J. Feldman, Wesley Scott Harper
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Publication number: 20110184649Abstract: A method and system for the evaluation of the probability for the presence of suspicious materials is presented. The proposed system will be able to continuously monitor a large area or a gate passage, without a specific need for a manual full-body search or manual inspection or the use of sniffers or sniffing dogs (although the system can be embedded within such a gate), and will allow to detect suspicious materials, not by identifying the specific material, but rather by at least one of the chemical and/or physical analysis of the commonality of all detected materials against the statistical accumulation database of all material properties that were presented to the system in the past.Type: ApplicationFiled: December 12, 2007Publication date: July 28, 2011Applicant: Physical Logic AGInventor: Eran Ofek
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Patent number: 7987060Abstract: A method of processing Fourier Transform Mass Spectrometry (FTMS) data includes performing a Fourier Transform of a part of a time domain transient and identifying from that transformed data signal peaks representative of the presence of ions. After peak identification, the full transient is then transformed, and the peaks identified in the partial transient transform are used to locate true peaks in the transformed full transient. The number of ‘false’ peaks resulting from random noise has been found to correlate to the resolution, so that using a partial transient to identify true peaks reduces the risk of false peaks being included; nevertheless this information can then be applied to the full data set when transformed. As an alternative, different parts of the full data set can be transformed and then correlated; because any noise will be random, false peaks should occur at different places in the two partial transforms.Type: GrantFiled: November 23, 2005Date of Patent: July 26, 2011Assignee: Thermo Finnigan LLCInventors: Oliver Lange, Michael W. Senko
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Patent number: 7982181Abstract: A method of analyzing data from a mass spectrometer provides data-dependent acquisition. An extracted ion chromatogram (XIC) is created for each m/z data point of mass spectral scans and the XIC for each m/z data point are correlated to a model function to obtain a XIC correlation value. A weighting function is applied to the XIC correlation value to obtain a current weighted intensity for each m/z point, which is used to reconstruct a weighted mass spectrum. The value or range of intensities of interest of the weighted intensity data or raw data is transformed from the time domain into the frequency domain, and the transformed data is used to make a real-time decision for the data-dependent acquisition. The data-dependent acquisition can be the performance of tandem mass spectrometry. A sample processing apparatus receives the sample and a computer readable medium provides instructions to the apparatus.Type: GrantFiled: January 15, 2008Date of Patent: July 19, 2011Assignee: Thermo Finnigan LLCInventor: Michael W. Senko
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Patent number: 7976467Abstract: A meter is provided that includes an improved user interface that enables the user to take a specific action, leading them directly to data input options. Such a user interface could be used to input first selected information, such as whether a test was premeal or postmeal, immediately after receiving a result. Optionally, the user interface may include the ability to add an additional comment after inputting the first selected information. Provision of such a user interface would facilitate simpler capture of the first selected information each time the user performs a test, leading to an enhanced understanding of a patient's level of glycemic control. Designing a user interface to enable first selected information to be entered by a user directly after receiving a result is more likely to engage a patient by making it easy and simple to enter important information. This may enable capture of the information thought to be most pertinent e.g.Type: GrantFiled: December 29, 2005Date of Patent: July 12, 2011Assignee: Lifescan Scotland, Ltd.Inventors: Stanley Alan Young, David William Taylor, Allan Orr, Cheryl Neary, Nicola Canning, Marc Daniel Stern
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Patent number: 7977626Abstract: A method and apparatus for performing time of flight mass spectrometry wherein the number of sums of transients taken for generating a given spectra is determined as a function of a characteristic of the incoming data for that spectrum. For instance, the number of transient measurements taken for a given spectrum output can be determined as a function of the abundance of ions in the sample or the abundance of ions corresponding to a base peak or another selected peak. In yet another embodiment, the collection of transients is terminated when a threshold signal to noise ratio is attained.Type: GrantFiled: June 14, 2007Date of Patent: July 12, 2011Assignee: Agilent Technologies, Inc.Inventors: August Jon Hidalgo, Bryan David Miller, Gregor T. Overney
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Publication number: 20110166796Abstract: A testing method for the bolt to be used under the conditions of excessive wind force by which bolts made of Cr—Mo steel can be separated into a group of bolts usable in cold areas and a group of bolts unusable in cold areas without conducting Charpy impact test involving complicated operation, specifically, a testing method for determining whether bolts made of heat-treated Cr—Mo steel are usable or unusable in cold areas, wherein the determination is conducted on the basis of both J parameter calculated by formula: J=(Si %+Mn %) (P %+Sn %) 104 (wherein P %, Si %, Mn % and Sn % are contents (mass %) of phosphorus (P), silicon (Si), manganese (Mn) and tin (Sn) respectively as disclosed in the inspection certificate of the Cr—Mo steel) and bolt diameter.Type: ApplicationFiled: January 9, 2009Publication date: July 7, 2011Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Shin Nakayama, Masuo Tada, Tomohiro Numajiri
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Patent number: 7972863Abstract: A method and apparatus is provided for determining concentration of components in a liquid hydrocarbon mixture including hydrocarbons and water flowing through an alkylation process. A fluid flow path conveys the liquid continuously from the alkylation process through a first instrument configured for measuring a property of the liquid mixture, and having responsivities to concentration of the components, which are independent of the concentration of the water. A temperature detector generates temperature data for the liquid, and a second instrument measures another property of the liquid mixture. The instruments have mutually distinct responsivities to concentrations of the components.Type: GrantFiled: March 9, 2010Date of Patent: July 5, 2011Assignee: Invensys Systems, Inc.Inventors: W. Marcus Trygstad, Russell Jackson, Bruce A. Keen
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Patent number: 7968054Abstract: A system for receiving, analyzing and communicating results of sensing chemical and/or physical parameter values, using wireless transmission of the data. Presence or absence of one or more of a group of selected chemicals in a gas or vapor is determined, using suitably functionalized carbon nanostructures that are exposed to the gas. One or more physical parameter values, such as temperature, vapor pressure, relative humidity and distance from a reference location, are also sensed for the gas, using nanostructures and/or microstructures. All parameter values are transmitted wirelessly to a data processing site or to a control site, using an interleaving pattern for data received from different sensor groups, using I.E.E.E. 802.11 or 802.15 protocol, for example. Methods for estimating chemical concentration are discussed.Type: GrantFiled: March 7, 2007Date of Patent: June 28, 2011Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA)Inventor: Jing Li
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Patent number: 7966131Abstract: Methods of determining analyte concentration. The methods use a fraction of the predicted total charge, from analyte electrolysis, instead of using time, for determination of a data collection endpoint. The total charge is then extrapolated from the data collection endpoint. The analyte concentration is determined from the total charge.Type: GrantFiled: May 8, 2009Date of Patent: June 21, 2011Assignee: Abbott Diabetes Care Inc.Inventors: Ting Chen, Benjamin J. Feldman
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Patent number: 7957906Abstract: A calculated vertical velocity sensor signal is determined from a recorded pressure sensor signal. A constructed vertical velocity sensor signal is determined as a linear combination of the calculated vertical velocity sensor signal and a recorded vertical velocity sensor signal in dual-sensor seismic streamer data, using a mixture coefficient as a proportionality constant. An upgoing pressure wavefield component is determined as one half of a difference of the recorded pressure sensor signal and the constructed vertical velocity sensor signal, as a function of the mixture coefficient. An error in the upgoing pressure wavefield component is determined by propagating errors in the recorded pressure sensor signal and constructed vertical velocity sensor signal terms. A value of the mixture coefficient is determined that minimizes the error in the upgoing pressure wavefield component.Type: GrantFiled: May 7, 2008Date of Patent: June 7, 2011Assignee: PGS Geophysical ASInventor: Neil Turnbull
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Patent number: 7955862Abstract: Provided are a process and a device for the qualitative and/or quantitative determination of a protein and/or peptide pattern of a liquid sample taken from a human or animal body for checking its state. The peptides and proteins of the liquid sample are processed and then subjected to analysis, wherein reference and sample values describing states of a human or animal body as well as deviations and correspondences derived therefrom are established, automatically stored in a data base, and when the protein and/or peptide pattern is again determined, a search for optimum correspondence is automatically performed. In this process, mass components or structural components of the proteins and/or peptides are established and stored.Type: GrantFiled: January 27, 2004Date of Patent: June 7, 2011Assignee: Mosaiques Diagnostics and Therapeutics AGInventor: Harald Mischak
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Patent number: 7957917Abstract: A computer system. The computer system including a processor and memory unit coupled to the processor, the memory unit containing instructions that when executed by the processor implement a method for monitoring a solution in a tank used to fabricate integrated circuits, the method comprising the computer implemented steps of: (a) collecting data indicating of an amount of copper in a region of a substrate of a monitor, the monitor comprising an N-type region in a silicon substrate, the region abutting a top surface of the substrate, the monitor having been submerged in the solution for a preset time; (b) comparing the data to a specification for copper content of the solution; (c) if the data indicates a copper content exceeds a limit of the specification for copper, indicating a corrective action is required to prevent copper contamination of the integrated circuits; and (d) repeating steps (a) through (c) periodically.Type: GrantFiled: September 28, 2007Date of Patent: June 7, 2011Assignee: International Business Machines CorporationInventors: Jay Sanford Burnham, Joseph Kerry Vaughn Comeau, Leslie Peter Crane, James Randall Elliott, Scott Alan Estes, James Spiros Nakos, Eric Jeffrey White
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Patent number: 7953558Abstract: Disclosed embodiments of the present invention provide means to obtain correct gas density and flux measurements using (i) gas analyzer (open-path, or closed-path gas analyzers with short intake tube, for example 1 m long, or any combination of the two); (ii) fast temperature or sensible heat flux measurement device (such as, fine-wire thermocouple, sonic anemometer, or any other device providing fast accurate gas temperature measurements); (iii) fast air water content or latent heat flux measurement device (such as, hygrometer, NDIR analyzer, any other device providing fast accurate gas water content measurements); (iv) vertical wind or sampling device (such as sonic anemometer, scintillometer, or fast solenoid valve, etc.) and (v) algorithms in accordance with the present invention to compute the corrected gas flux, compensated for T-P effects.Type: GrantFiled: September 3, 2009Date of Patent: May 31, 2011Assignee: Li-Cor, Inc.Inventors: George Burba, Dayle McDermitt, Anatoly Komissarov, Tyler G. Anderson, Liukang Xu, Bradley A. Riensche
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Patent number: 7952066Abstract: Embodiments of the present invention relate to methods, systems, and apparatus suitable for performing a survey scan of one or more analytes or labeled fragments of analytes to obtain a convoluted spectrum and to de-convolute the convoluted spectrum using, for example, a mass spectrometer and associated processing system.Type: GrantFiled: October 11, 2007Date of Patent: May 31, 2011Assignee: DH Technologies Development Pte. Ltd.Inventors: Darryl J.C. Pappin, Nikita Khainovski, Darryl S. Spencer
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Method for monitoring an arrangement for determining the concentration of an analyte in a body fluid
Patent number: 7949477Abstract: The invention relates to a method for monitoring an arrangement for determining a concentration of an analyte in a body fluid. The determination of the concentration of the analyte by means of the arrangement involves a procedure in which the analyte from the body fluid passes through an interface and is transported in a stream of liquid into a flowmeter chamber, in which a measurement is carried out to determine the concentration of the analyte. The evaluation of the measurement takes place in a signal processor. The monitoring of the arrangement comprises the following steps: measurement of measured values of at least two correlated system parameters of the arrangement by means of a sensor system, and comparison of the measured values with limit values stored for each of the system parameters in a storage unit, to obtain a combination of at least two comparison results.Type: GrantFiled: December 23, 2008Date of Patent: May 24, 2011Assignee: Roche Diagnostics Operations, Inc.Inventors: Helmut Rinne, Gregor Ocvirk -
Patent number: 7949476Abstract: A method for estimating molecule concentrations in a sample, the method including: obtaining a signal generated by a sample analyzing apparatus, the signal including at least one spectrum, the spectrum including peaks representative of the molecule concentrations in the sample and being expressed as a function of at least one variable; obtaining an analytical modeling of the signal with a modeling function, wherein the modeling function is based on the molecule concentrations and factors including gain factors of the equipment and description factors of the peaks; selecting uncertain factors in the factors; determining a priori probability distributions for the uncertain factors and the molecule concentrations; establishing, with the modeling function and the signal, posteriori probability distributions for the molecule concentrations and the uncertain factors; and estimating, with a processing module, the molecule concentrations and the uncertain factors from a parameter inferred from the posteriori probabilType: GrantFiled: August 21, 2008Date of Patent: May 24, 2011Assignee: Commissariat a l'Energie AtomiqueInventors: Gregory Strubel, Jean-Francois Giovannelli, Pierre Grangeat
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Patent number: 7949432Abstract: An apparatus and method for monitoring and controlling microbiological activity in a process stream by measuring dissolved oxygen is disclosed.Type: GrantFiled: November 20, 2007Date of Patent: May 24, 2011Assignee: Nalco CompanyInventor: Laura E. Rice
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Patent number: 7945394Abstract: A method of detecting incomplete filling of an electrochemical biosensor by collecting a series of electrical current values when a constant electrical potential is applied across the working and counter electrodes during a preliminary burn period. The slope of a line determined by linear regression based on the series of current values is used to determine whether or not the biosensor is incompletely filled. If the line has a positive slope, the biosensor is reported to be under filled. If the slope is not positive, the correlation coefficient of the current values is used as a supplemental test to indicate whether or not the biosensor is incompletely filled.Type: GrantFiled: June 16, 2005Date of Patent: May 17, 2011Assignee: Bayer Healthcare LLCInventors: Daniel V. Brown, Christina Blaschke
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Patent number: 7937226Abstract: A method and a device determine a physical property of a medium, such as a concentration of a substance in the medium. The device includes a light source; a probe with optical fibers positioned alongside each other, with a first optical fiber delivering radiation from the light source to a sample and collecting first backscattered radiation from the sample, and with a second optical fiber collecting second backscattered radiation; a spectrometer for producing first and second signals based on the first and second backscattered radiation; and a processor which determines a differential backscatter signal from the first and second signals and to calculate the physical property by curve fitting the measured differential backscatter signal to a backscatter function. Depending on whether the diameter of the optical fibers is smaller or greater than the mean free path of photons in the sample, different backscatter functions are used.Type: GrantFiled: September 22, 2004Date of Patent: May 3, 2011Assignees: Erasmus University Medical Center, Stichting voor de Technische WetenschappenInventors: Arjen Amelink, Henricus Josephus Cornelis Maria Sterenborg
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Publication number: 20110097649Abstract: The present invention measures a quantity of attachment (such as density) of a material (such as catalyst and promoter) attached to a carrier. A carrier 1 includes attachment holes 12 to which a catalyst 24 attaches, and non-attachment holes 14 to which the catalyst 24 does not attach, where extension directions of the attachment holes 12 and the non-attachment holes 14 are parallel with each other (perpendicular to a first end surface 1a), and are opened on the first end surface 1a and a second end surface 1b. An attachment quantity measurement device includes an electromagnetic wave output device 2 that outputs a terahertz wave at a frequency equal to or more than 0.Type: ApplicationFiled: October 29, 2009Publication date: April 28, 2011Applicant: ADVANTEST CORPORATIONInventors: Motoki IMAMURA, Shigeki NISHINA
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Patent number: 7933430Abstract: The spectral method for determining the concentrations of a substance in a mixture of any number of substances is defined by a chemical image having a plurality of pixels (520). The method includes steps of providing a spectrum for each of the n number of substances in the mixture (530), and obtaining the spectrum for one of the plurality of pixels, and calculating a plurality of estimated concentrations of each substance in the mixture as a function of the spectrum for each substance and the spectrum for the pixel, and calculating a deviation value for each of the plurality of estimated concentrations as a function of the spectrum of each of the number of substances in the mixture, and selecting the estimated concentration with the lowest deviation factor as a most likely concentration of each substance in the mixture (550).Type: GrantFiled: April 15, 2005Date of Patent: April 26, 2011Assignee: ChemImage CorporationInventor: Robert Schweitzer
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Publication number: 20110093213Abstract: The invention relates to a fluid providing apparatus (5; 34) for providing a fluid to an analyzing apparatus (17; 33) for analyzing the fluid and to the analyzing apparatus (17; 33). The fluid providing apparatus (34) comprises a casing (35), which has an introduction opening (7), through which a fluid transferring element (1) is introducible into the casing (35) for transferring the fluid to the fluid providing apparatus (34). The casing (35) comprises further a fluid releasing section (8) for releasing the fluid from the fluid transferring element (1) and a fluid transferring element detection section (36) for detecting whether the fluid transferring element (1) is introduced into the casing (35) by interacting with a fluid transferring element detection unit of the analyzing apparatus (17; 33).Type: ApplicationFiled: June 22, 2009Publication date: April 21, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Petrus Johannes Wilhelmus Van Lankvelt, Dominique Maria Bruls, Albert Hendrik Jan Immink
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Publication number: 20110093212Abstract: Method for measuring a moisture value F of dielectric materials using at least one microwave resonator, one shift A of the resonant frequency being respectively evaluated for at least two resonance modes with resonant frequencies which are different from one another and a density-independent moisture value being calculated from the measured shifts in the resonant frequency.Type: ApplicationFiled: July 25, 2008Publication date: April 21, 2011Applicant: TEWS ELECTRONIK DIPL. ING. MANFRED TEWSInventors: Rainer Herrmann, Udo Schlemm, Hendrik Richter
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Patent number: 7927878Abstract: The invention describes a process for the determination of the concentration distribution and size distribution of lipoprotein classes in body fluids, e.g. blood. For this purpose, NMR spectra of a sample to be analysed are measured by magnetic field gradient intensities and temperatures under different diffusion-weighted measuring conditions selected according to different pulse programs (e.g. PFG-STE, PFG-LED etc) and consequently in a differentiated manner according to the relaxation times. The different effects of these measuring conditions on the intensity/line form of the NMR signals of the individual lipoprotein classes are determined and permit the determination of a concentration distribution/size distribution of the individual lipoprotein classes.Type: GrantFiled: June 1, 2005Date of Patent: April 19, 2011Assignee: LipoFIT Analytic GmbHInventors: Werner Kremer, Hans Robert Kalbitzer, Fritz Huber
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Patent number: 7930157Abstract: A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in hydrophobicity (?Hydr) between the reference polypeptide and a modified polypeptide, calculating the difference in ?-sheet propensity (??Gcoil-?+??G?-coil) between the reference polypeptide and modified polypeptide, calculating the difference in charge (? Charge) between the reference polypeptide and modified polypeptide, and calculating: [x*?Hydr]+[y*(??Gcoil-?+??G?-coil)]?[z*?Charge], wherein x, y and z are scaling factors.Type: GrantFiled: April 4, 2008Date of Patent: April 19, 2011Assignee: Cambridge University Technical Services Ltd.Inventors: Christopher Dobson, Fabrizio Chiti, Jesus Zurdo
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Patent number: 7925449Abstract: Products and processes are provided herewith for analyzing octane content in a fuel sample that include the step or steps of receiving an octane measurement of a fuel sample from a octane analyzer, rounding the octane measurement to a nearest recognized octane rating, comparing the rounded octane measurement with a listed octane rating for the fuel sample, and communicating results of the comparison to a user of the octane analyzer. The octane analyzer may be incorporated into a fuel pump or a vehicle. The results of the comparison may also be used to adjust the vehicle operating parameters to account for the actual octane rating of the fuel dispensed into the vehicle.Type: GrantFiled: September 18, 2007Date of Patent: April 12, 2011Assignee: CFPH, LLCInventors: Howard W. Lutnick, Antonio Papageorgiou
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Patent number: 7917313Abstract: The present invention relates to a method for monitoring a fluid transfer process, including the steps: providing an allowable pressure profile; detecting a pressure occurring in the course of the fluid transfer process; comparing detected pressure with the allowable pressure profile and signaling an error, if the detected pressure is not within the allowable pressure profile. The allowable pressure profile is defined by interpolation points, the interpolation points being based on a probability function representing a family of pressure courses of a plurality of fluid transfer processes. The allowable pressure profile can be divided into at least two distinct process sections, each section corresponding to a distinct process phase of the fluid transfer process. The probability function is calculated from a family of test pressure curves and reflects the statistical behavior of the pipette system.Type: GrantFiled: August 27, 2008Date of Patent: March 29, 2011Assignee: Roche Molecular Systems, Inc.Inventors: Guenter Ziegler, Peter Wenzig
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Patent number: 7917308Abstract: The invention relates to a process for determining a molecular weight distribution in a polymer. When a polymer is prepared, chains of different length are formed. Correspondingly, a distribution of the molecular weights of the chains of a polymer arises. It is an object of the invention to be able to determine the molecular weight distribution in an improved manner compared to the prior art. The object of the invention is achieved by describing starting data G*(?) available in numerical form, i.e. the complex shear modulus measured as a function of frequency or the mastercurve constructed therefrom, are described by an analytical function. In this way, exact knowledge of the relaxation behaviour is available in improved form, in particular also in the case of prolonged relaxation times. This enables a valid determination of the relaxation time spectrum and hence a fundamentally more valid calculation of the molecular weight distribution.Type: GrantFiled: November 6, 2007Date of Patent: March 29, 2011Assignee: LANXESS Deutschland GmbHInventors: Claus Wrana, Jochen Kroll
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Patent number: 7912655Abstract: A meter adapted to determine and store an analyte concentration reading, in particular a glucose concentration reading, and including an interface having a plurality of predefined levels of user features. The predefined levels may be selected by a user based on the user's preferences, needs and abilities.Type: GrantFiled: August 3, 2006Date of Patent: March 22, 2011Assignee: Bayer HealthCare LLCInventors: Barry D. Power, Jeffrey A Culver
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Publication number: 20110066386Abstract: The invention discloses an anesthetic sensing optical microfluidic chip system. The anesthetic sensing optical microfluidic chip system includes a biochip, a light source, and a detector. The biochip includes a substrate, a micro-channel, and a molecularly imprinted biosensor. The micro-channel is bonded beyond the substrate. The molecularly imprinted biosensor is disposed in the micro-channel, and a surface of the molecularly imprinted biosensor has a plurality of imprinted sites. When a sample including a plurality of anesthetic molecules is injected into the micro-channel and flowing through the surface of the molecularly imprinted biosensor, some of the anesthetic molecules are captured by the imprinted sites. The light source emits a sensing light to the plastic biochip, and the detector receives the sensing light passing through the imprinted sites on the surface of the molecularly imprinted biosensor and generates a detecting result based on the received sensing light.Type: ApplicationFiled: September 16, 2009Publication date: March 17, 2011Inventors: Chien-Chong Hong, Po-Hsiang Chang, Chih-Chung Lin
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Patent number: 7908093Abstract: A mass spectrometer comprises an ion detector, an analog-to-digital (A/D) converter, a sample adjuster, and an adder. The A/D converter is configured to generate digital samples representing an analog signal received from the ion detector during a mass scan. The adder is configured to sum the samples with corresponding unsuppressed samples representing analog signals received from the ion detector during previous mass scans, the summed samples defining a mass spectrum. The sample adjuster is configured to identify a peak defined by the samples and to suppress all but one of the samples defining the identified peak to enhance resolution of a peak in the mass spectrum.Type: GrantFiled: August 8, 2008Date of Patent: March 15, 2011Assignee: Agilent Technologies, Inc.Inventors: John Christian Fjeldsted, August Jon Hidalgo, William Daniel Frazer