Abstract: The invention provides methods of treating Friedreich's ataxia using histone deacetylase inhibitors.

Abstract: A hardware sensor and a hardware user-input component are integrated in a portable electronic device. The hardware sensor is operable to produce hardware sensor output indicative of orientation or motion or both of the device within its environment. The hardware user-input component has multiple elements operable to accept user input through touch. A user-input driver and the device's operating system are jointly operable to detect touch events involving the elements. A software application stored in the device's memory is executable by the device's processor as a process. A sensor driver or the operating system or both are configured to control what hardware sensor output, if any, is receivable by the process. This control may thwart an attack based on analysis of the hardware sensor output, the attack designed to deduce what user input has been made via multiple elements of the hardware user-input component.

Abstract: A compact heat exchanger for veno-venous perfusion-induced hyperthermia includes an integral pneumatic pump and a hollow tubule heat exchange array. A veno-venous perfusion-induced hyperthermia system incorporating the compact heat exchanger is described. The heat exchanger provides a compact, efficient design allowing a lesser heat exchanging surface area and lesser required pumping power compared to conventional systems. In turn, the system provides a shorter blood circuit compared to conventional systems, allowing maintaining a lower blood temperature than such conventional systems while supplying sufficiently heated blood to patient visceral organs to provide a therapeutic effect, such as in supplementing chemotherapy drugs.

Abstract: The present invention uses the principles of electrochemical ion absorption (charging) and ion desorption (discharge), and relates to a continuous flow-electrode system, a high-capacity energy storage system, and a water treatment method using the same, in which high-capacity electric energy is stored as electrode materials of a slurry phase and electrolytes simultaneously flow in a successive manner within a fine flow channel structure formed on an electrode. More specifically, the present invention relates to a continuous flow-electrode system, an energy storage system, and a water treatment method, wherein electrode active materials consecutively flow in a slurry state whereby a high capacity is easily obtained without enlarging or stacking electrodes.

Abstract: An adaptive controller for a static compensator (STATCOM) to enhance voltage stability comprises an outer voltage regulator loop and an inner current regulator loop. Each of the outer loop and the inner loop comprises a proportional integral controller. The outer loop adjusts proportional and integral control gains of voltage regulator. The inner loop adjusts proportional arid integral parts of current regulator gains. The automatic adjustment of these regulator gains is adaptively determined such that the voltage at the controlled bus follows a desired voltage, reference curve over time returning to a desired steady-state condition under various disturbances such as changes in load and/or transmission network. Thus, the adaptive controller can achieve a plug-and-play feature for a STATCOM without human intervention.

Abstract: A polypeptide in crystalline form comprises a G-protein coupled receptor (GPCR) with an IC3 loop substituted by an amino acid residue sequence of lysozyme.

Abstract: The present disclosure relates to a system and method for selecting a network for use by a communication device to process a data transmission. In the method, the following actions are conducted: tracking transmission characteristics of networks used by the device; maintaining a set of options for the device relating to the networks, including at least one option based on the transmission characteristics; utilizing a selected option identify a selected network to process the data transmission by the communication device; and processing the data transmission using the selected network.

Abstract: A communications device includes a plurality of wireless transmitters operable at different respective frequencies and each configured to generate respective IQ signals having an initial IQ imbalance. The communications device also includes a frequency tunable auxiliary receiver, and a controller. The controller is configured to selectively couple a given wireless transmitter to the frequency tunable auxiliary receiver and tune the frequency tunable auxiliary receiver to a frequency of the given wireless transceiver, and apply predistortion to the given wireless transmitter based upon the initial IQ imbalance to reduce the initial IQ imbalance.

Abstract: Holographic display apparatuses are provided. The holographic display apparatus may include a light source module generating coherent light, at least two input optical systems converging the light generated from the light source module on at least two converging points, an output optical system mixing the lights provided from the at least two input optical systems to provide a hologram image, and a spatial light modulating module modulating the light.

Abstract: Provided is an apparatus and method for controlling a smart appliance using a smart terminal to induce a user to reduce energy consumption in response to a demand response signal from an energy utility. The apparatus and method may motivate a user to reduce energy consumption effectively and actively in response to the demand response signal from the energy utility by allowing the user to report a demand response-based user-defined event to a pre-registered smart terminal, and to control a user-premises smart appliance using the smart terminal.

Abstract: Dithioamine reducing agents useful for the reduction of disulfide bonds. The reducing agents of this invention are useful, for example, to reduce disulfide bonds, particularly in proteins, or to prevent the formation of disulfide bonds, particularly in proteins and other biological molecules. Reducing agents of this invention are useful and suitable for application in a variety of biological applications, particularly as research and synthetic reagents. The invention provides S-acylated dithioamines which can be selectively activated reducing agents by removal of the S-acyl groups enzymatically or chemically. The invention further provides dithiane precursors of thioamino reducing agents. The invention provides dithioamine reducing agents, S-acylated dithioamines and dithianes which are immobilized on surfaces, including among others, glass, quartz, microparticles, nanoparticles and resins.

Abstract: The present technology relates to a method of treating cancer by sensitizing human tumours to DNA damaging therapies through activating FBXO32 expression. Transactivation of FBXO32 through the inhibition of EZH2, a histone methyltransferase, decreases p21 protein induction which results in the sensitization of human tumours to chemotherapy. The method further provides a prognostic method to determine if a combination treatment would be effective.

Abstract: An apparatus and method for estimating a location of an object within a mobile reference frame. Sensor data is received from an accelerometer associated with an object followed by determining from the sensor data that the mobile reference frame is executing one of a set of pre-determined maneuvers. In response to such determination: (1) the sensor data is applied to a mathematical model associated with the executed maneuver, the model trained with previously obtained data from one or more reference accelerometers positioned at known locations within the mobile reference frame and estimating the location of the object by applying the sensor data to the mathematical model; and/or (2) incorporating reference accelerometers in the mobile reference frame and comparing the sensor data with the reference accelerometers and estimating the location of the object.

Abstract: A chrysanthemum plant named ‘Zanmuaval Purple’ characterized by its medium sized blooms with dark purple ray florets and prolific branching; natural season flower date week 42; blooming for a period of five weeks.

Abstract: A method for controlling channel access performed by an access point (AP) in a wireless system is provided. The method includes: receiving at least one frame from at least one station (STA), respectively, for a specific time period, each frame including information on a contention window (CW) used when the frame is transmitted; processing information one at least one CW for each STA; determining whether to control the channel access based on the processed information on the CW; selecting an abnormal STA candidate group if it is determined that the channel access control is performed; and controlling the channel access to each STA included in the abnormal candidate STA group.

Abstract: Disclosed are an apparatus and a method for providing integrated developing environment for a network application using various network processors, and a server using the same. The apparatus for integrally developing a network application, includes: an application storing part configured to store an application produced by a user; an application attribute managing part configured to manage attribute information for the application, including input information, output information, and information regarding a connection between an input and an output; a target code creating part configured to compile the application stored in the application storing part based on the attribute information stored in the application attribute managing part and create a target code corresponding to the compiled application; and a code loading part configured to mount the target code created by the target code creating part in hardware.

Abstract: This invention relates to the field of human waste handling, treatment and disposal in mobile public carriers. In particular the invention is directed to a self- sustained bio-digester for onboard degradation of human waste.

Abstract: The present invention discloses compositions of liquid and gel formulation containing aripiprazole in the form of a patch for transdermal delivery.

Abstract: A method of increasing insulin content in a pancreatic beta cell is disclosed. The method comprising expressing in the pancreatic beta cell an exogenous polynucleotide encoding at least one microRNA or a precursor thereof, wherein the microRNA is selected from the group consisting of miR-15, miR-16, miR-24, miR-26, miR-27, miR-29, miR-30, miR-129, miR-141, miR-148, miR-182, miR-200, miR-376 and Let-7, thereby increasing the insulin content in the pancreatic beta cell.

Abstract: A laticiferous tissue-specific SRPP (small rubber particle-associated protein) promoter derived from Hevea brasiliensis, consists of nucleotide sequence of SEQ ID NO: 1. A recombinant plant expression vector includes the promoter. A plant is transformed with the recombinant plant expression vector and seed of the transformed plant is obtained. A method for laticiferous tissue-specific expression of a foreign gene in a transformed plant includes performing recombination of a foreign gene into the recombinant plant expression vector. The transformed plant produced by the method shows laticiferous tissue-specific expression of a foreign gene.