Abstract: This disclosure describes compounds of the formula ##STR1## where R.sub.1 represents hydrogen, fluoro, chloro, lower alkyl having 1 to 4 carbon atoms or lower alkoxy having 1 to 4 carbon atoms, andR.sub.2 and R.sub.3 each independently represent lower alkyl as defined above, orR.sub.2 and R.sub.3 together with N represent ##STR2## wherein n is 1, 2 or 3, andR.sub.4 and R.sub.5 each independently represent hydrogen or lower alkyl as defined above,or a pharmaceutically acceptable acid addition salt thereof, which are useful as anti-diabetic agents in particular as hypoglycemic agents and inhibiting or impeding post-prandial hyperglycemia.

Abstract: Disazo compounds of the formula ##STR1## in which A is a diazo component radical,B is a coupling/diazo component radical of the 1,4-phenylene, 1,4-naphthylene or 5,6,7,8-tetrahydro-1,4-naphthylene series,R.sub.3 is hydrogen (C.sub.1-4)alkyl or ##STR2## wherein ring Z is unsubstituted or monosubstituted by halo, (C.sub.1-4)alkyl or (C.sub.1-4)alkoxy, andR.sub.4 is (C.sub.1-6)alkyl, (C.sub.1-6)alkoxy, amino mono(C.sub.1-6)alkylamino or di(C.sub.1-6) alkylamino,with the proviso that the compound contains a single sulpho group on the diazo component radical A and no other water-solubilizing group, which compound is in free acid or salt form, and mixtures of such compounds which are useful as anionic dyestuffs for dyeing and printing substrates such as natural and synthetic polyamides (e.g., wool, silk and nylon), leather, polyurethanes and polyolefins modified to contain basic groups. The dyes may be used as such or in the form of liquid (e.g., concentrated aqueous) or solid preparations.

Abstract: Compounds of formula I, ##STR1## wherein X is oxygen or sulphur, and R.sub.1 -R.sub.6 are various substituents.The compounds are useful for treating coronary insufficiency, intermittent claudication, cerebrovascular insults, spasms in muscles and hypertension.

Abstract: Asymmetrical phosphate esters of formula I ##STR1## in which R is C.sub.1-20 alkyl,R.sub.1 is C.sub.1-20 alkyl,R.sub.2 is hydrogen or methylx is 1-15and M is hydrogen, an alkali metal ion or an equivalent of an alkali earth metal or zinc ionare effective inhibitors of oxidative corrosion of metals in the presence of electrolytes. They may be used alone or in conjunction with further additives, and are preferably dissolved in the electrolyte with which the metal is to come in contact.

Abstract: Disazo, trisazo and tetrakisazo compounds of the formula ##STR1## in which each D.sub.1 independently is a disazo component of the aniline series or the naphthylamine series;each K.sub.1 independently is a coupling and disazo component of the aniline series or the naphthylamine series;each K.sub.2 independently is a coupling component of the aniline series or the naphthylamine series;each m independently is 0 or 1;Y is a bridging group attached to the amino group of each K.sub.2, which bridging group is other than one having two alkylene end groups;Z and Z.sub.Z are basic or cationic groups;b is 0 to 2; andn is at least 1,with the proviso that the compounds are free of sulfo groups,are useful as dyes for dyeing and printing cellulosic substrates such as cotton and paper and leather, particularly paper.

Abstract: A method for dyeing or printing a textile substrate with disperse dyes comprising using a compound of formula I ##STR1## wherein each R.sub.1, independently, is C.sub.4-14 alkyleach R.sub.2, independently, is H or C.sub.1-10 alkyl with the proviso that the sum of the carbon atoms present in R.sub.1 and R.sub.2 borne by the same phenyl ring is from 6 to 18 an average of 0.5 to n of the R.sub.3 's are --SO.sub.3 R.sub.4, --CH.sub.2 CO.sub.2 R.sub.4 or ##STR2## the remaining R.sub.3 's being H each R.sub.4, independently, is H, an alkali metal, an equivalent of an alkali earth metal, ammonium, or substituted ammonium,R.sub.5 and R.sub.6 are both H, with the proviso that in, on average, up to 60% of the units --CHR.sub.5 --CHR.sub.6 --one of the groups R.sub.5 or R.sub.6 may be methyl,each m, independently, is an integer from 4 to 20, and n is an integer from 1 to 9,or a mixture thereof together with a dyeing assistant.

Abstract: The present invention provides a nasal or pulmonary pharmaceutical composition comprising as active agent a compound of formula I, ##STR1## wherein R.sub.1 is hydrogen or halogen,R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms,either (i)R.sub.3 is isopropyl, sec-butyl, or isobutyl,R.sub.4 methyl, ethyl or isopropyl andR.sub.5 is hydrogen and R.sub.6 is hydrogen or methoxyor R.sub.5 and R.sub.6 are together a single bond,or (ii)R.sub.3 is benzyl, R.sub.4 is methyl, R.sub.5 is hydrogen and R.sub.6 is hydrogen or methoxy, or (III) dihydroergocristine,in association with a pharmaceutically acceptable carrier or diluent, adapted for nasal or pulmonary administration.

Abstract: A stable aqueous solution comprising(a) 5-25% by weight of an optical brightening agent of formula I ##STR1## in which R.sub.1 to R.sub.9, X and A.sup..crclbar. are defined in the specification(b) 5-70% by weight of an organic monobasic acid or a mixture of organic monobasic acids selected from formic, acetic, propionic, butyric, glycollic and lactic acids,(c) 0-45% by weight citric acid(d) 5-55% by weight waterthe total amount of organic acids present being at least 40% by weight of the total composition, and the total amount of components a, b, c and d being at least 90% of the total solution.

Abstract: The compounds of formula I, ##STR1## where R.sub.1, R.sub.2 and R.sub.3 have various significances, and physiologically acceptable hydrolyzable derivatives thereof having the hydroxy group in the 2 position of the 3-aminopropoxy side chain in esterified form, are useful as cardiotonic, antiarrhythmic, .alpha.- and .beta.-adrenoceptor blocking agents.

Abstract: The invention relates to a new process for preparing alkoxylates containing primary amine functions comprising reacting a monoalkanolamine or a polyamine compound with a carbonyl compound to form an amide- or carbamate-type condensation product, reacting said condensation product with an alkylene oxide compound to form an alkylene oxide adduct of said condensation product, and salifying the so-formed adduct under mild, acidic conditions.

Abstract: The invention provides novel N-amino-2-oxo-3-oxazo-lidine derivatives, e.g. 2-methoxy-N-(2,6-dimethylphenyl)-N-(2-oxo-3-oxazolidinyl)-acetamide, which are useful as fungicides. Other objects of the invention are fungicidal compositions comprising such novel compounds and methods of combating phytopathogenic fungi in plants, seeds or soil with the aid of said novel compounds.

Abstract: A group of diphosphonic acid tetra-esters and phosphonic or thiophosphonic acid 0,0,0-triesters containing dioxaphosphorinane rings are useful as flame retardants for polymeric organic materials, particularly polyesters. The compounds, some of which are novel, are prepared by reaction of the corresponding phosphites with peroxy compounds or with sulphur.

Abstract: The compounds are secondary amides of the formulaA--C.tbd.CO--NH--BwhereinA is alkyl, a mono- or poly-ethylenically unsaturated acyclic hydrocarbon chain, or a hydrocarbon chain having from 1 to 4 cyclopropanyl units thereon; andB is a radical which may be of the phenyl, benzyl, phenylalkyl, benzocycloalkyl or indol- type, e.g., N-[1-phenyl-2-(p-methylphenyl)-ethyl]-oct-2-ynoylamide.The compounds are useful as pharmaceutical agents.

Abstract: The present invention relates to naphthoquinone derivatives of formula I, ##STR1## in which R.sub.1 signifies a halogen atom, a nitro group or an unsubstituted or substituted alkoxy or amino group,R.sub.2 signifies the atoms necessary to form an unsaturated ring system, which ring system has 1 or 2 nuclei and is unsubstituted or substituted,R.sub.3 signifies an unsubstituted or substituted s-triazinyl or pyrimidyl radical, andn is 0, 1 or 2,which compounds are free from sulphonic acid groups are useful as pigments or disperse dyes.

Abstract: Tranquilizers are of the formula I: ##STR1## wherein R.degree. is hydrogen, halo of atomic weight of from 18 to 80, i.e. fluoro, chloro or bromo, or alkyl of 1 to 3 carbon atoms,R is hydrogen, halo of atomic weight of from 18 to 80, alkyl of 1 to 4 carbon atoms, nitro or trifluoromethyl,n is 0 or 1,R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen or alkyl of 1 or 2 carbon atoms, with the proviso that no more than 2 of R.sub.1, R.sub.2 and R.sub.3 are other than hydrogen,Z is ##STR2## R' is hydrogen or alkyl of 1 or 2 carbon atoms, Y.degree. is hydrogen, halo of atomic weight of from 18 to 80 or alkyl of 1 to 3 carbon atoms,Y is hydrogen, halo of atomic weight of from 18 to 80, alkyl of 1 to 4 carbon atoms, trifluoromethyl or nitro,p is 1 or 2,q is 0, 1 or 2, andm is 0, 1, 2, 3 or 4.

Abstract: This disclosure describes compounds of the formula ##STR1## wherein R.sub.1 represents hydrogen, fluoro, chloro, lower alkyl having 1 to 4 carbon atoms, or lower alkoxy having 1 to 4 carbon atoms, andR.sub.2 represents lower alkyl or ##STR2## where R.sub.5 represents hydrogen, fluoro, chloro, lower alkyl or lower alkoxy, andR.sub.3 and R.sub.4 each independently represent lower alkyl as defined above, andR.sub.3 and R.sub.4 together with N represent ##STR3## or pharmaceutically acceptable acid addition salts thereof, which are useful as anti-diabetic agents.

Abstract: The wet fastness properties of direct or reactive dyeings on cellulosic substrates are improved by aftertreatment with a precondensate or mixture of(A) the product of reacting a polyalkylenepolyamine in free base or salt form with an epihalohydrin or a precursor thereofand (B) and N-methylol derivative of a urea, melamine, guanamine, triazinone, urone, carbamate or acid amidein the presence of(C) a catalyst for the cross-linking of N-methylol compounds of the type (B) above,followed by a heat-curing step.

Abstract: Minor tranquilizers preparable by known processes are represented by the following structural formula I: ##STR1## wherein R.sup.o is hydrogen, halo of atomic weight of from 18 to 80, i.e. fluoro, chloro or bromo or alkyl of 1 to 3 carbon atoms,R is halo of atomic weight of from 18 to 80, alkyl of 1 to 4 carbon atoms or trifluoromethyl,R' is alkenyl of 3 to 6 carbon atoms, alkynyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, norbornyl, alkyl of 1 to 3 carbon atoms substituted by cycloalkyl of 3 to 7 carbon atoms or --CH.sub.2 (F.sub.x ALK) wherein x is 1 to 3 and ALK is alkyl of 1 to 4 carbon atoms,R.sub.1, R.sub.2, and R.sub.3 are independently hydrogen or alkyl of 1 or 2 carbon atoms, andn is 0 or 1.

Abstract: The invention provides novel pharmaceutical compositions useful in the treatment of thrombosis in mammals, comprising a mixture of dihydroergotamine or a related ergot alkaloid and heparin.

Abstract: Tranquilizers are of the formula: ##STR1## wherein R.degree. is alkyl of 1 to 8 carbon atoms, andn is 1 or 2.