Patents Assigned to SANDOZ
  • Patent number: 4543128
    Abstract: Coloring compositions comprising an aqueous paste or dispersion of a filler which has been dyed with a water-soluble polycationic dyestuff, preferably together with a binding agent, are used in the coating of paper and the fixing, dyeing and printing of non-woven fabrics, including tissue paper.
    Type: Grant
    Filed: August 23, 1983
    Date of Patent: September 24, 1985
    Assignee: Sandoz Ltd.
    Inventors: Juerg Troesch, Walter Portmann
  • Patent number: 4543103
    Abstract: A glass substrate is dyed or printed with a water-soluble polycationic dyestuff in the absence of a size or binding agent. The resulting dyeings have good rubbing fastnesses.
    Type: Grant
    Filed: April 16, 1984
    Date of Patent: September 24, 1985
    Assignee: Sandoz Ltd.
    Inventor: Jurg Troesch
  • Patent number: 4542022
    Abstract: Silyl-alkyn-en-ylamine derivatives which possess pharmaceutical in particular anti-mycotic activity.
    Type: Grant
    Filed: January 20, 1982
    Date of Patent: September 17, 1985
    Assignee: Sandoz Ltd.
    Inventor: Anton Stutz
  • Patent number: 4542135
    Abstract: 9-Thia ergot cyclic peptide alkaloids produced by fermentation or synthetic methods have interesting anti-parkinson and other pharmacological activities.
    Type: Grant
    Filed: August 3, 1982
    Date of Patent: September 17, 1985
    Assignee: Sandoz Ltd.
    Inventors: Hans Kobel, Jean-Jacques Sanglier, Hans Tscherter, Georg Bolliger
  • Patent number: 4540775
    Abstract: The compound of the formula, ##STR1## a pigment existing in a yellow (.alpha.) modification and an orange (.beta.) modification, the latter being obtained by treatment of the .alpha. form with boiling organic solvents, is useful for the mass pigmenting of synthetic plastics and resins, free from or containing solvents, such as viscose, cellulose acetate, polyethylene, polystyrene, polyvinyl chloride and synthetic leathers and rubbers, of surface coatings such as paints and lacquers and of inks and for pigment printing, textile coating and pigmenting paper in the mass.
    Type: Grant
    Filed: May 11, 1981
    Date of Patent: September 10, 1985
    Assignee: Sandoz Ltd.
    Inventor: Bansi L. Kaul
  • Patent number: 4540525
    Abstract: Disclosed is a method for producing 1-naphthol-4-sulphonic acid in free acid form and contaminated with less than 2% by weight of the isomeric 1-naphthol-2-sulphonic acid.
    Type: Grant
    Filed: August 30, 1984
    Date of Patent: September 10, 1985
    Assignee: Sandoz Ltd.
    Inventor: Werner Veit
  • Patent number: 4536499
    Abstract: This disclosure describes novel compounds of the formula ##STR1## where m is 2, 3 or 4X is hydrogen or hydroxyR.sub.1 represents hydrogen, fluoro, chloro, lower alkyl having 1 to 4 carbon atoms or lower alkoxy having 1 to 4 carbon atoms, andR.sub.2 and R.sub.3 each independently represent lower alkyl as defined above, orR.sub.2 and R.sub.3 together with N represent ##STR2## wherein n is 1, 2 or 3, andR.sub.4 represents hydrogen or lower alkyl as defined above, andR.sub.5 represents hydrogen, lower alkyl, phenyl or phenyl substituted with fluoro, chloro, lower alkyl having 1 to 4 carbon atoms, or lower alkoxy having 1 to 4 carbon atoms, with the proviso that when X is hydroxy, m is 3 or 4,or a pharmaceutically acceptable acid addition salt thereof, which are useful in the treatment of diabetes by inhibiting or impeding post-prandial hyperglycemia.
    Type: Grant
    Filed: April 1, 1983
    Date of Patent: August 20, 1985
    Assignee: Sandoz, Inc.
    Inventors: Leonard J. Brand, Jeffrey Nadelson
  • Patent number: 4532287
    Abstract: Compositions for flameproofing polymeric material comprising:(a) a halogenated alkylaryl ether, the aryl group of which may be substituted by halogen;(b) an organo-tin compound; and(c) a sterically hindered phenol or a bisphenol containing a sterically hindered --OH group on each phenyl.In this specification by the term "bisphenol" is meant a compound containing two phenol groups linked by a bridging group that is not attached to any other bisphenol groups and by the term "phenol" is meant compounds containing only a single phenol group.
    Type: Grant
    Filed: May 11, 1984
    Date of Patent: July 30, 1985
    Assignee: Sandoz Ltd.
    Inventors: Rudolf Bill, Rainer Wolf
  • Patent number: 4531979
    Abstract: Anodically oxidized aluminium or aluminium alloy surfaces are sealed in the presence of an anti-smut agent which is a colorless, light-fast, organic compound having a molecular weight of at least 350 and containing(i) at least one sulphonic acid group; and(ii) a carboxy group and a hydroxy group both aromatically bound and located ortho- to each other on the same aromatic ring, preferably a benzene ring.
    Type: Grant
    Filed: August 1, 1983
    Date of Patent: July 30, 1985
    Assignee: Sandoz Ltd.
    Inventors: Hans Bohler, Ernst Weisskopf
  • Patent number: 4530842
    Abstract: The compounds of formula I ##STR1## wherein R, R.sub.1 and R.sub.2 have various significances, are useful as agents against heart insufficiency.
    Type: Grant
    Filed: May 12, 1983
    Date of Patent: July 23, 1985
    Assignee: Sandoz Ltd.
    Inventor: Gerhard Bormann
  • Patent number: 4529754
    Abstract: A lacquer composition comprising a water soluble reaction product of(a) a water soluble acrylic polymer or copolymer having pendant amine groups, and(b) a glycidyl ether of a di- or polyhydric alcohol or monomeric phenolic compound having 2-4 aromatic hydroxy groupswith the proviso that per amine equivalent of component (a) 0.5-0.85 epoxide equivalents of component (b) are present, the reaction product being hardened by a mixture of component (b) above and a glycidyl ether of a polymeric phenol-aldehyde condensate or of polyamine derived from ethyleneimine and/or propyleneimine.The composition is useful for coating such substrates as leather.
    Type: Grant
    Filed: November 9, 1982
    Date of Patent: July 16, 1985
    Assignee: Sandoz Ltd.
    Inventor: Werner Walther
  • Patent number: 4528191
    Abstract: This disclosure relates to the aspermatogenesis activity of compounds of the following formula: ##STR1## where R.sub.1 and R.sub.2 each independently represent hydrogen, halo having an atomic weight of about 19 to 36, lower alkyl having 1 to 4 carbon atoms, lower alkoxy having 1 to 4 carbon atoms, trifluoromethyl, orR.sub.1 is ##STR2## and R.sub.2 is hydrogen, whereinR.sub.7 and R.sub.8 are each independently hydrogen or lower alkyl having 1 to 2 carbon atoms,n is 0 or 1, andR.sub.3, R.sub.4, R.sub.5 and R.sub.6 each independently represent lower alkyl having 1 to 2 carbon atoms ora pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 6, 1984
    Date of Patent: July 9, 1985
    Assignee: Sandoz, Inc.
    Inventor: Sandor Barcza
  • Patent number: 4526302
    Abstract: So as to use easily in atomizing the content of a sectile ampule, the invention provides a unitary device comprising a tubular element fitted at one end with a hand actuated spraying pump, the other end of the tubular element being open for forming a tubular housing designed for receiving the sectile ampule.
    Type: Grant
    Filed: June 1, 1984
    Date of Patent: July 2, 1985
    Assignee: Sandoz Ltd.
    Inventor: Michel Brunet
  • Patent number: 4526963
    Abstract: Disclosed are dioxazine compounds of formula I ##STR1## in which each R, independently, is C.sub.1-4 alkyl, their production and use as pigments.
    Type: Grant
    Filed: October 28, 1982
    Date of Patent: July 2, 1985
    Assignee: Sandoz Ltd.
    Inventor: Michel Deur
  • Patent number: 4526976
    Abstract: Compounds of formula I ##STR1## in which X is O or S;Y is O, S or NR.sub.3 where R.sub.3 is hydrogen or C.sub.1-4 alkyl (preferably methyl or ethyl) and rings A and B may be further substituted by non-chromophoric substituents.
    Type: Grant
    Filed: March 30, 1983
    Date of Patent: July 2, 1985
    Assignee: Sandoz Ltd.
    Inventors: Fritz Fleck, Alec V. Mercer, Malcolm Oates
  • Patent number: 4518391
    Abstract: Compounds of the formula ##STR1## wherein D is ##STR2## wherein R.sub.1 is H or SO.sub.3 H, andR.sub.2 is H, halo, CH.sub.3, OCH.sub.3 or --NHCOCH.sub.3, andY is ##STR3## wherein R.sub.3 is H or ##STR4## R.sub.5 is C.sub.1-4 alkyl or monosubstituted by chloro, cyano orhydroxy, C.sub.1-4 alkyl, andR.sub.6 is halo, C.sub.1-4 alkyl or C.sub.1-4 alkoxy,and mixtures of such compounds, which compounds are in free acid or salt form, are useful for dyeing or printing hydroxy group- or nitrogen-containing organic substrates, particularly leather and textiles containing or consisting of natural or synthetic polyamides or of natural or regenerated cellulose, especially textile materials containing or consisting of cotton.
    Type: Grant
    Filed: September 12, 1983
    Date of Patent: May 21, 1985
    Assignee: Sandoz Ltd.
    Inventor: Guenther Auerbach
  • Patent number: 4516979
    Abstract: The invention relates to a method of dyeing or printing a textile substrate with disperse dyes, using as a dyeing assistant the product of polyesterifying an aliphatic polyol or etherpolyol or a disaccharide with benzoic acid or substituted benzoic acid.
    Type: Grant
    Filed: December 23, 1982
    Date of Patent: May 14, 1985
    Assignee: Sandoz Ltd.
    Inventor: Hans-Peter Baumann
  • Patent number: 4515950
    Abstract: The invention concerns a process for the isomerization of ergoline derivatives substituted in the 8.beta. position by an electron withdrawing radical to the corresponding 8.alpha. compounds by removal of the proton in the 8.alpha. position and by a following, separately effected, protonation.
    Type: Grant
    Filed: April 26, 1982
    Date of Patent: May 7, 1985
    Assignee: Sandoz Ltd.
    Inventors: Zdenek Brich, Herbert Muhle
  • Patent number: 4515802
    Abstract: A process for the production of an improved and well tolerated analgesic preparation of paracetamol which comprises formulating tizanidine and paracetamol using e.g. granulating techniques and optionally putting up into tablet form, e.g. using compression and moulding techniques to produce tablets and suppositories.
    Type: Grant
    Filed: March 8, 1984
    Date of Patent: May 7, 1985
    Assignee: Sandoz Ltd.
    Inventor: Dietmar Romer
  • Patent number: 4511707
    Abstract: The wet fastness properties of direct or reactive dyeings on cellulosic substrates are improved by aftertreatment with a precondensate of(A) the product of reacting a mono- or polyfunctional primary or secondary amine with cyanamide, dicyandiamide (DCDA), guanidine or biguanidine; or ammonia with cyanamide or DCDA; whereby up to 50 mole % of the cyanamide, DCDA, guanidine or biguanide may be replaced with a dicarboxylic acid or a mono- or di-ester thereof, said product (A) containing reactive hydrogen atoms bound to nitrogen, and either(B) an epihalohydrin or a precursor thereof, or(C) formaldehyde or a formaldehyde precursor, or(D) a dihydroxyalkyleneurea or a methyl ether thereof,followed by formaldehyde or a formaldehyde precursor optionally together with(E) an N-methylol derivative of a urea, melamine, guanamine, triazinone, urone, carbamate or acid amideand, if (A) is used with (C) or (D), or if (E) is present, together with(F) a catalyst for the cross-linking of N-methylol compounds of the type (E) abov
    Type: Grant
    Filed: January 25, 1984
    Date of Patent: April 16, 1985
    Assignee: Sandoz Ltd.
    Inventors: James R. Runyon, Salvatore Valenti