Abstract: 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones, eg. 1-isopropyl-7-methyl-4-phenyl-quinazolin-2(1H)-one, are useful as platelet aggregation inhibitors.

Abstract: This disclosure describes compounds of the formula ##STR1## wherein R.sub.1 represents ##STR2## and R.sub.2, R.sub.3, R.sub.4 and R.sub.5 each independently represent lower alkyl having 1 to 2 carbon atoms, andn is 1 or 2,which are useful as muscle-relaxant agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, chlorine or lower alkyl,R.sub.2 is lower alkyl,R.sub.3 is lower alkyl, each ofA and B is hydrogen, orA and B together form a bond,useful as luteinizing hormone secretion inhibitors, e.g. for the treatment of prostate hypertorphy.

Abstract: The compounds are amino- or cyano-bearing dihydroquinolines, which have either of the combinations of (a) 2-amino, 3-carboxylic and 4-oxo functions, or (b) 2-oxo, 3-cyano and 4-hydroxy functions, and may be optionally substituted at 1 or 2 of the 5, 6, 7 or 8 positions, eg 1-allyl-2-amino-1,4-dihydro-6,7-dimethoxy-4-oxo-quinoline-3-carboxylic acid ethyl ester, and 1-allyl 3-cyano-1,2-dihydro-4-hydroxy-6,7-dimethoxy-2-oxo-quinoline. The compounds are useful as pharmaceuticals.

Abstract: Quaternated polyamine salts of formula, ##STR1## in which R signifies alkyl, alkenyl, phenylakyl or naphthylalkyl,R.sub.1 signifies phenylalkyl or naphthylalkyl,x and y signify integers, and additionally y signifies O,each R.sub.2 and R.sub.3, independently, has one of the significances of R.sub.1 or signifies a group, at least one being present, of formula ##STR2## wherein x, R and R.sub.1, are as above. each R.sub.4, independently, signifies a quaternating C.sub.1-6 alkyl radical,z signifies a number in the range 0.5 to 1.8, being an average number of quaternated nitrogen atoms per molecule,and each A.sup..crclbar., independently, signifies an anion,are useful as levelling agents in the dyeing with basic dyestuffs of polyacrylonitrile-containing fibrous materials.

Abstract: The invention relates to novel, polymeric phosphate esters containing at least two orthophosphate groups bridged by a polyoxyalkylene radical, and to the use of said esters as emulsifiers, surfactants, dispersants and fiber finishing agents.

Abstract: The present invention relates to cyclosporin derivatives, especially compounds of formula I ##STR1## wherein A is ##STR2## useful as anti-arthritic agents.

Abstract: Flameproofed polymeric organic materials, e.g. regenerated cellulose, which include bis-(2-oxo-1,3, 2-dioxaphosphorinanyl) oxides, bis-(2-thiono-1,3,2 -dioxaphosphorinanyl) oxides and 2-oxo-1,3,2-dioxaphosphorinanyl-2'-thiono-1',3',2'-dioxaphosphorinanyl oxides, having at least one substituent on the dioxaphosphorinane rings, as flameproofing agents, and their production. Some of the flameproofing agents are new compounds and are included in the invention.

Abstract: Anti-diabetic agents of the formula: ##STR1## wherein R is CHO or COOR.sub.1, where R.sub.1 is hydrogen or C.sub.1-6 alkyl,R.sub.o is C.sub.1-4 alkyl, C.sub.1-4 alkoxy, bromo, chloro, fluoro, trifluoromethyl, nitro or ##STR2## where R.sub.2 is hydrogen or C.sub.1-4 alkyl, andn is 0 or 1,and the non-toxic, pharmaceutically acceptable salts thereof.

Abstract: This disclosure describes novel compounds of the formula: ##STR1## where A is --CH.sub.2 OH or ##STR2## wherein R.sub.4 and R.sub.5 each independently represent hydrogen or lower alkyl having 1 to 2 carbon atoms or together with N represent ##STR3## and, R.sub.1 is hydrogen or lower alkyl having 1 to 2 carbon atoms, andR.sub.2 and R.sub.3 each independently represent hydrogen, chloro, fluoro, methyl, methoxy or together, represent methylenedioxy, andn is 1 or 2, provided that one of R.sub.2 and R.sub.3 is other than hydrogen which are useful as hypolipidemic agents.

Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is hydrogen or lower alkyl,R.sub.2, R.sub.3 and R.sub.4 are, independently, hydrogen, halogen lower alkyl, lower alkoxy or CONR.sub.5 R.sub.6 wherein R.sub.5 and R.sub.6 are, independently, hydrogen or lower alkyl, and x y is --CH.sub.2 --CH.dbd. or --CH.dbd.C.dbd..are useful as central dopaminergic agents and prolactin secretion inhibitors.

Abstract: Multicolored substrates, particularly nylon carpeting, are produced by applying combinations of a colorless reserving agent and an acid, direct or basic dye or mixture of dyes and fixing the reserving agent and the dye(s) simultaneously.

Abstract: Compounds of the formula, ##STR1## in which D is a diazo component radical of the benzene, pyrazole, thiophene, thiazole, isothiazole or thiadiazole series,K is 1,4-phenylene, substituted 1,4-phenylene or 1,4-naphthylene,R.sub.1, in the case where K is 1,4-naphthylene, is hydrogen or (C.sub.1-4)-alkyl or, in the case where K is 1,4-phenylene or substituted 1,4-phenylene, R.sub.1 is hydrogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkyl monosubstituted by chlorine, bromine, vinylsulphonyl, hydroxy, cyano, (C.sub.1-2)alkoxy, phenyl, acetyl, phenoxy, formyloxy, alkyl(C.sub.1-3)carbonyloxy, benzoyloxy, alkoxy(C.sub.1-2)carbonyl, alkoxy(C.sub.1-2)carbonyloxy, (C.sub.1-2)alkylaminocarbonyl, di(C.sub.1-2)alkylaminocarbonyl or --CO--O--C(U.sub.1 U.sub.2)--C.tbd.C--U.sub.3 ; (C.sub.3-4)alkyl substituted by hydroxy and one further substituent selected from the group consisting of chlorine, (C.sub.1-4) alkoxy, hydroxy, phenoxy and benzyloxy; (C.sub.2-4)alkenyl; chloro(C.sub.3-4)alkenyl or bromo(C.sub.3-4)alkenyl,R.sub.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, independently, are hydrogen, halogen, nitro, cyano, hydroxy, alkyl, alkoxy or akylthio, wherein any alkyl moiety contains 1 to 4 carbon atoms,useful an anti-rigor agents, myotonolytics and muscle relaxants.

Abstract: Antibiotics active against gram positive bacteria are produced from Microellobosporia brunea nov. Sp. King 1977.

Abstract: This invention provides new antibiotics produced by cultivating a strain of the fungus species, Cylindrocarpon lucidum Booth or Tolypocladium inflatum Gams in contact with a nutrient medium, the antibiotics being useful anti-inflammatory and immunosuppressive agents.

Abstract: 2-amino-4H-3,1 benzoxazines, eg 6-chloro 2-dimethylamino-4H, 3,1-benzoxazine, are useful as herbicides. The compounds may be prepared by reacting an amine with a 2-halomethylphenyl isocyanate.

Abstract: Sulfo group-free basic disazo and trisazo dyes of the formula ##STR1## wherein R is hydrogen; unsubstituted C.sub.1-4 alkyl; C.sub.2-4 -alkyl monosubstituted by hydroxy, the hydroxy being on other than the .alpha.-carbon atom; di-(C.sub.1-4 alkyl)amino or --CH.sub.2).sub.n Ko,R.sub.1 is hydrogen, C.sub.1-4 alkyl, C.sub.1-4 hydroxyalkyl or C.sub.1-4 alkoxy,n is 2 or 3,Ko is --N(CH.sub.3).sub.2, --N.sup..sym. (CH.sub.3).sub.3 A.sup..crclbar., --N.sup..sym. (CH.sub.3).sub.2 CH.sub.2 CH.sub.2 OH A.sup..crclbar. or ##STR2## each A.sup..crclbar. is an anion, Zo is a direct bond or a bridging group, andKx is a radical of a coupling component of the pyrazolone-5,5-aminopyrazole, .beta.-naphthol, .alpha.-naphthol, aniline, phenol or acetoacetylphenylamide series or the radical of barbituric acid, dimedone or a dimedone carboxylic acid ester,which compounds, where Kx is a radical of a coupling component of the pyrazolone-5,5-aminopyrazole, .beta.-naphthol, .alpha.

Abstract: Azo dyes of the formula ##STR1## wherein D is an aromatic carbocyclic or heterocyclic diazo component radical,R is hydrogen or optionally substituted hydrocarbyl, heterocyclyl or amino,R" is quaternized nitrogen-containing heterocyclyl,R.sub.1 is hydrogen or cyano,R.sub.2 is optionally substituted alkyl, aryl or heterocyclyl,Y is a divalent bridge member,K.sub.1.sup..sym. is optionally substituted ammonium, hydrazinium or quaternized nitrogen-containing heterocyclyl,m is 1 or 2,r is 0 or 1, andA.sup..crclbar. is an anion.The Y.sub.r -K.sub.1.sup..sym. group is preferably attached to the nitrogen atom of the pyridone ring or to the diazo component radical D. These dyes are well-suited for dyeing and printing textiles which consist of or contain fibers of polyacrylonitrile or acrylonitrile copolymers as well as polyamides and polyesters that have been modified to contain acid groups.

Abstract: Complexes of the formula ##STR1## in which each of X.sub.1 and X.sub.2, independently, is --COO-- or --O--,each of B.sub.1 and B.sub.2, independently, is the radical of a coupling component of the benzene series containing up to two non-condensed benzene rings or a radical of a coupling component of the quinoline series, which coupling component radicals are free from acid groups,each of ##STR2## independently, is the radical of a diazo component of the benzene series in which the rings A.sub.1 and A.sub.2 shown are free from acid groups bound directly thereto,each of the floating sulpho groups on the naphthalene rings, independently, is in the 3- or 4-position, which complexes are free from fibre reactive groups and are in free acid or salt form, and mixtures of such complexes are useful as anionic dyestuffs for substrates comprising or consisting of, for example, natural or regenerated cellulose, natural or synthetic polyamides, leather, polyurethanes or polymers modified to contain basic groups.