Abstract: Certain substituted or unsubstituted 2-phenylbenzimidazoles, e.g., 1-methyl-2-phenylbenzimidazole, are useful as anti-obesity agents.

Abstract: An improved process for the preparation of optionally substituted 2,3-indolinediones which are useful as intermediates in the preparation of compounds having pharmacological activity which comprises reacting a 3,1-benzoxazine with an alkali or alkaline earth metal cyanide or a tetra-(C.sub.1-4) alkylammonium cyanide to obtain a 2-imino-3-indolinone, which is then subjected to hydrolysis.

Abstract: Fluorene phosphonites and thiophosphonites of the formula, ##STR1## in which each R, independently, is alkyl or optionally substituted phenyl, each Y, independently, is oxygen or sulphur, and n is zero or 1, are useful as antioxidants. Organic materials, which are susceptible to the degradative effects of oxygen, are treated with one or more of such compounds e.g. by incorporation into the body of the organic material, in order to be stabilized against such effects.

Abstract: Water-soluble acid addition or quaternary ammonium salts of compounds produced by acylation of an excess of diethylene triamine by isophthalic or terephthalic acid or a functional derivative thereof, subsequently cyclizing the product to afford imidazoline groups, and reacting the product further by way of acylation with a bifunctional acylating agent which is a saturated aliphatic dicarboxylic acid or a functional derivative thereof, or a functional derivative of carbonic acid. Such salts are useful for eliminating or preventing the brightening effect on materials, e.g. such fibrous material as textiles and paper, of anionic optical brightening agents.

Abstract: The present invention provides cyclosporin C which can be hydrogenated to produce dihydrocyclosporin C of formula, ##STR1## useful as an immunosuppressive.

Abstract: Flameproofed, regenerated cellulose containing as a flameproofing agent a compound of the formula, ##STR1## in which both Y's, are oxygen or sulphur,both R.sub.1 's are cyclohexyl or optionally substituted phenyl, or additionally methyl when Y is sulphur, andboth R.sub.2 's are a radical --NR.sub.3 R.sub.4, whereinR.sub.3 is hydrogen or alkyl andR.sub.4 is alkyl, cyclohexyl or optionally substituted phenyl, orR.sub.3 and R.sub.4 together with the common nitrogen atom form a saturated heterocyclic ring,with the proviso that when Y is oxygen, R.sub.3 is hydrogen and R.sub.1 is optionally substituted phenyl, R.sub.4 is only optionally substituted phenyl.

Abstract: Dibenz[c,f]imidazo[1,2-a][1]azepin-9-ols of the general formula ##STR1## where R.sub.1 represents H or mono or di-chloro or fluoro, andR.sub.2 represents H, chloro, fluoro, alkyl of 1-3 carbon atoms, e.g., methyl, ethyl or isopropyl, alkoxy of 1-3 carbon atoms, e.g., methoxy or ethoxy, or trifluoromethyl,prepared by borohydride hydrogenation of the corresponding 9-ones are useful as anti-convulsant agents.

Abstract: This disclosure describes novel compounds of the formula: ##STR1## where R.sub.1 and R.sub.2 each independently represent hydrogen, halo having an atomic weight of about 19 to 36, lower alkyl, lower alkoxy,trifluoromethyl or R.sub.1 is ##STR2## and R.sub.2 is hydrogen, whereinR.sub.7 and R.sub.8 are each independently hydrogen or lower alkyl andn is 0 or 1, andR.sub.3, R.sub.4, R.sub.5 and R.sub.6 each independently represent lower alkyl, which are useful as muscle relaxants.

Abstract: 2-Hydroxy-n-propylamines of formula, ##STR1## in which R is a mono- or dialkylphenolpoly-(C.sub.2-3)-alkyleneglycolether group bound through an oxygen atom and containing at least 8 (C.sub.2-3)alkyleneoxy units of which at least 50% are ethyleneoxy, R.sub.1 is hydrogen or alkyl, optionally substituted with hydroxyl or X, R.sub.2 is alkylene, optionally substituted with hydroxyl, and X is an acid group, the compounds being in free acid or salt form, are useful as surface active agents, especially for use as dispersing or emulsifying agents in textile lubricant and fat liquor emulsions, and as agents for the degreasing of pelts and leathers, as tanning auxiliary agents and for the desizing of textile materials.

Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,X is sulphur,a group ##STR2## or a group .dbd.N--R.sub.4.sup.I, whereineither Y and Z are both sulphur, orone of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.I is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members, and pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The compounds are antibiotics with an antibacterial effect.

Abstract: Substituted hydroxy pyridones, e.g., 3-(.alpha.-iminobenzyl)-4-hydroxy-6-phenyl-1-methyl-2-(1H)-pyridone, are prepared by reducing corresponding isoxazolo[4,5-c]pyridin-4(5H)-ones and are useful as minor tranquilizers and sleep inducers.

Abstract: Novel compounds based on a hydroxybiphenyl nucleus in which the hydroxy group is in the para position relative to the other phenyl ring and has an adjacent tertiary alkyl radical, are useful stabilizers for organic compounds against heat, light or oxygen.

Abstract: Certain known imidazo[2,1-a]isoindoles and isoquinolines, e.g., 5-(p-chlorophenyl)-5-hydroxy-2,3-dihydro-5H-imidazo[2,1-a]isoindole (mazindol), have been found to be useful as inhibitors of prolactin secretion, and may be so utilized alone or as an agent which enhances the action of other chemical compounds having activity in inhibiting prolactin secretion.

Abstract: Cyclopropanyl-group-bearing-hydrazides, e.g. cis-2-octyl-cyclopropanoctanoic acid, 2-(o-methylphenyl)-hydrazide, are useful as pharmaceutical agents and are obtainable by reacting a derivative, e.g. mixed anhydride, of a cyclopropanyl-group bearing-long chain carboxylic acid with an appropriate hydrazine.

Abstract: Disclosed is a treatment process for textile substrates comprising or consisting of regenerated cellulose, which process comprises applying to the substrate an aqueous medium comprising (A) a monomeric, hydrolysis stable, hydrosoluble, resin forming cross linking agent containing at least two N-methylol or N-alkoxymethyl groups, (B) a hydrosoluble, prepolymerized, linear, filler resin forming, cross-linking agent, also containing at least two N-methylol or N-alkoxymethyl groups, (C) a reactive acetal of formula ##STR1## wherein X and Y, independently, are H or CH.sub.2 OH, (D) a first cross-linking catalyst, being an alkaline earth metal salt of a strong acid and (E) a second cross-linking catalyst, being an acidic aluminium salt, subsequently drying the substrate and subjecting same to a temperature at which cross-linking takes place, and an aqueous concentrate for use therein.

Abstract: The present invention relates to a novel exhaust-dyeing process to obtain level dyeings which is characterized by the step of regulating the parameters that affect the rate of adsorption of the dye onto the substrate in order to prevent the rate of bath exhaustion as a function of the number of cycles of dye liquor and/or substrate from exceeding a predetermined limit. The invention also relates to an apparatus for effecting said process.

Abstract: A process for the dyeing of paper with granulated dyeing preparations, preferably dissolved in water. For the process granulated dyeing preparations are used which consist of(a) a dye soluble to at least 2% in water at 25.degree. C. and(b) in an amount not greater than 50%, a salt which dissociates in water, the average size of the granules being at least 20 microns.This application is a continuation of application Ser. No. 239,360, filed Mar. 29, 1972 and now abandoned, which in turn is a continuation-in-part of application Ser. No. 60,115, filed July 31, 1970 and now abandoned, which in turn is a continuation-in-part of application Ser. No. 761,333, filed Sept. 20, 1968 and now abandoned.

Abstract: Disclosed are compounds of formula I ##STR1## in which R.sub.1 and R.sub.4, independently, are hydrogen, a non-chromophoric second order substituent, or alkyl or alkenyl unsubstituted or substituted by a non-chromophoric group,R.sub.2 and R.sub.5, independently, are hydrogen or alkyl or alkenyl, unsubstituted or substituted by a non-chromophoric group,R.sub.3 and R.sub.6, independently, are hydrogen, alkyl, carboxyl or a non-chromophoric esterified carboxyl group,or R.sub.2, together with R.sub.3, and/or R.sub.5 together with R.sub.6, signify an alkylene bridge,R.sub.7 and R.sub.8, independently, signify hydrogen or a non-chromophoric substituent,or, when R.sub.7 is in the 3-position and/or R.sub.8 in the 3' position, R.sub.7 together with R.sub.2, and/or R.sub.8 together with R.sub.5 signify an alkylene bridge,with the proviso that no more than one of R.sub.1 and R.sub.2 and no more than one of R.sub.4 and R.sub.5 signify hydrogen,their production and use as optical brightening agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is alkyl or 2 to 5 carbon atoms, andR.sub.2 is methyl or ethyl,useful as anti-migraine agents and for the treatment of orthostatic disorders.

Abstract: The present invention concerns novel flameproofed regenerated cellulose incorporating, as flameproofing agent, a phosphoric acid or thiophosphoric acid mono- or triamide.