Abstract: 2,4-Disubstituted-4b,5,6,7,8,8a,9,10-octahydro-9-oxo-phenanthrenes e.g., 2,4-dimethoxy-4b,5,6,7,8,8a,9,10-octahydro-9-oxo-phenanthrene are useful as hypolipidemic agents.

Abstract: Compounds of the formula ##STR1## WHEREIN R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms or amino, R.sub.2 is hydrogen or alkyl of 1 to 6 carbon atoms, with the provisos that (1) at least one of R.sub.1 and R.sub.2 is not a tertiary alkyl group and (2) R.sub.2 is hydrogen when R.sub.1 is amino, orR.sub.1 and R.sub.2 taken together and with the nitrogen atom to which they are joined are pyrrolidino, piperidino or N'-2-hydroxyethylpiperazino,Each X' is independently alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms or halo, or two X's on adjacent carbon atoms together are methylenedioxy, andn is 0, 1, 2 or 3,And the pharmaceutically acceptable acid addition salts thereof,Are useful as anti-obesity and anti-diabetic agents. The compounds wherein R.sub.1 is alkyl and R.sub.2 is hydrogen are synthesized by a two-step synthesis from 2-alkyl-5-arylisoxazolium salts and ethylenediamine. The compounds wherein R.sub.1 and R.sub.

Abstract: Pesticidal compositions useful in agriculture but subject to rapid degradation on exposure to sunlight are stabilized by including in the formulation an amount of a sulfonated copolymer of catechin and leucocyanidin having a molecular weight in the range of about 3000 to 6000, or of an agronomically acceptable metal or ammonium salt thereof, in an amount sufficient to provide a concentration of about 1/4 lb. to 5 lbs. per acre.

Abstract: This invention provides compounds of formula I, ##STR1## wherein R.sub.1 is alkyl of 4 to 8 carbon atoms; cycloalkyl of 4 to 6 carbon atoms; phenethyl or phenethyl monosubstituted in the phenyl residue with fluorine, chlorine, bromine, methoxy or alkyl of 1 to 4 carbon atoms; 2-tetrahydrofurylmethyl or 2-furylmethyl,Useful as analgesic agents.

Abstract: The invention provides a mold for the molding of a resilient material to the insides of a container placed upon the mold.

Abstract: Free flowing, rapid dissolving, effervescent granules in particular, potassium chloride granules, are prepared by granulating an alkali metal carbonate and/or bicarbonate and active ingredient with water containing a surfactant, such as polyethylene glycol 1540, and after drying mixing with a pharmaceutically acceptable organic acid plus additives.

Abstract: The invention concerns a novel apparatus for automatically preparing a solution of controlled salt concentration, which comprises a mixer container in which preparation of the solution may take place, a regulator device for regulating supply of components of the solution to the mixer container, a level detector for detecting the level of solution in the mixer container in the vicinity of a prescribed primary level, a concentration probe for detecting concentration of salts in the solution, and a control device connected to receive electronic signals transmitted from said level detector and said concentration probe for producing a control output signal to control said regulator device, whereby the level of solution in the container is maintained in the vicinity of said prescribed primary level and the concentration of salts in the solution is maintained in the region of a predetermined value.

Abstract: The invention relates to a process which comprises reacting a compound of formula I, ##STR1## in which A.sub.1 is a radical which does not compete with the activity of the ##STR2## OR A TAUTOMER THEREOF, WITH A COMPOUND OF FORMULA II,a.sub.2 -- ch.sub.2 -- cn iiin which A.sub.2 is a radical which does not compete with the activity of the --CH.sub.2 CN group of the compound of formula II but provides the vicinal methylene group with sufficient acidity to react with the .dbd.NH group of the compound of formula I,and with sulphur,To obtain a compound of formula III, ##STR3## in which A.sub.1 and A.sub.2 are as defined above, which compounds of formula III are useful as intermediates for the production of dyestuffs.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, alkyl of 2 to 8 carbon atoms, or phenylalkyl of 7 to 9 carbon atoms, andR.sub.2 is branched alkyl of 3 or 4 carbon atoms or benzyl,Useful as agents for the treatment of migraine, hypotonia and orthostatic disorders.

Abstract: The compounds are 1-aryl-1-alknyl-1-(t-butyl)-substituted methanols, e.g. 3-(2'-naphthyl)-4,4-dimethyl-pent-1-yn-3-ol, are useful as hypolipidemic agents, and are prepared by reacting a 4-aryl-pivalophenone with a metallo-alkynyl reagent under Grignard reaction conditions.

Abstract: The present invention relates to a novel exhaust-dyeing process to obtain level dyeings which is characterised by the step of regulating the parameters that affect the rate of adsorption of the dye onto the substrate in order to prevent the rate of bath exhaustion as a function of the number of cycles of dye liquor and/or substrate from exceeding a predetermined limit. The invention also relates to an apparatus for effecting said process.

Abstract: Disclosed are cationic 1,4-diaminoanthraquinone dyestuffs, free from sulpho groups and containing a quaternary ammonium or protonized tertiary amino group bound to the 1-amino group through a propylene radical, and a xylyl group bound to the 4-amino group.

Abstract: Controlled gastric residence time medicament formulations, e.g., tablets and/or capsules, containing polymeric film coatings are exposed to a volatile amine, e.g., anhydrous ammonia, methyl amine, or ethyl amine, to provide improved medicament formulations, which by virtue of mechanical or surface effects including expansion or swelling of the coating in gastric fluids are capable of prolonged, e.g., up to twelve hours, residence in the gastric area.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein the indicated radical in the 8 or 9 position of the benzonaphthyridine structure (R.sub.1) is hydrogen, alkoxy of 1 to 4 carbon atoms or hydroxy, andR.sub.2, r.sub.3 and R.sub.4 are selected in certain combinations from hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, benzyloxy, hydroxy, halogen, nitro, amino, dimethylamino, or --NHCOR.sub.5wherein R.sub.5 is hydrogen or alkyl of 1 to 4 carbon atoms,Useful as bronchospasmolytics.

Abstract: Disclosed are disazo and trisazo dyes free of sulfo groups which contain two 6-hydroxy-4-methyl-3-N-pyridiniumpyridone-2 coupling component radicals, preferably dyes of the formula ##STR1## wherein R is a tetrazo component radical,Each R.sub.1 is independently hydrogen, C.sub.1-4 alkyl, C.sub.1-4 hydroxyalkyl or --NR.sub.3 R.sub.4,wherein each of R.sub.3 and R.sub.4 is independently n-C.sub.1-4 -alkyl,Each R.sub.2 is independently hydrogen, n-C.sub.1-4 alkyl, n-C.sub.1-4 -hydroxyalkyl or C.sub.1-4 alkoxy, andEach A.sup.- is an anion.The dyes are useful for dyeing paper and basically dyeable substrates such as polymers and copolymers of acrylonitrile and dicyanoethylene and synthetic polyesters and polyamides modified to contain acid groups. Dyeings on textiles are even and possess good light fastness.

Abstract: 6-(1-Piperazinyl)morphanthridine is a useful sleep promoting agent.

Abstract: The present invention provides compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms in position 1 or 2 of the indazole nucleus,R.sub.2 is hydrogen, halogen, trifluoromethyl, hydroxy or alkyl, alkylthio or alkoxy of 1 to 4 carbon atoms, or a group of formula II, ##STR2## wherein X is oxygen or sulphur,R.sub.3 is hydrogen, halogen, trifluoromethyl, hydroxy or alkyl, alkylthio or alkoxy of 1 to 4 carbon atoms, andR.sub.4 is hydrogen or a group of formula II, as defined above, with the proviso that one of R.sub.2 and R.sub.4 is a group of formula II and the other is other than a group of formula II,useful as myotonolytics and anti-hypertensives.

Abstract: Substituted or unsubstituted isoxazolyl benzamides, e.g., o-(3-phenylisoxazol-5-yl)-N-methylbenzamide, are prepared by cyclizing a corresponding 1-hydroxy-1-[substituted or unsubstituted -.beta.-(hydroxyimino)phenethyl]-2-alkyl phthalimidine with a strong acid and are useful as minor tranquilizers, muscle relaxants, and sleep inducers.

Abstract: This disclosure describes novel compounds of the formula ##STR1## where R.sub.1 is straight chain lower alkyl, andR.sub.2 and R.sub.3 independently represent hydrogen or lower alkyl or together with N represent ##STR2## where X is CH.sub.2, O or N--CH.sub.3, andR.sub.4 is hydrogen, halo having an atomic weight of about 19 to 36 or lower alkoxy which are useful as hypolipidemic agents.

Abstract: Disclosed are basic azo dyes, free from sulphonic acid groups, and of formula, ##STR1## in which Q signifies an unsubstituted or substituted phenyl or naphthyl radical,R.sub.1 signifies hydrogen, unsubstituted or substituted C.sub.1-4 alkyl, phenyl or cyclohexyl,Z signifies a ring forming residue,R.sub.4 signifies optionally substituted alkyl, alkenyl, alkoxy or cycloalkyl,K signifies a coupling component,A.crclbar. signifies an anion, andx signifies 1, 2 or 3.The dyes are useful for dyeing and printing textiles of polymers and copolymers of acrylonitrile and dicyanoethylene as well as synthetic polyamides and polyesters that have been modified to contain acid groups. The dyeings are level and exhibit good fastness to light, wet treatments, perspiration, sublimation, pressing and dry cleaning.