Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 or 2 carbon atoms;R.sub.2 is hydrogen or halogen of atomic number from 9 to 35;A.I. each of R.sub.3 and R.sub.4 is hydrogen, orIi. R.sub.3 and R.sub.4 together are oxygen, andI. R.sub.5 is hydrogen or alkyl of 1 to 4 carbon atoms, orIi. R.sub.5 and R.sub.7 are attached to the same carbon atom, and form an alkylene chain of 3 to 6 carbon atoms, orB. when A as defined hereinafter is --(CH.sub.2).sub.2 --R.sub.3 is hydrogen and R.sub.4 and R.sub.5 together form a bond;R.sub.6 is hydrogen or alkyl of 1 to 4 carbon atoms; andA is --(CH.sub.2).sub.n --,Wherein n is 0, 1 or 2 depending on the following:n may be 0 provided that R.sub.3 and R.sub.4 together are oxygen;n may be 1 provided that (i) at least one of R.sub.5, R.sub.6 and R.sub.7 is alkyl of 1 to 4 carbon atoms; (ii) R.sub.5 and R.sub.7 together form an alkylene chain of 3 to 6 carbon atoms; or (iii) R.sub.2 is halogen, R.sub.3 and R.sub.

Abstract: The purpose of the invention are new benzene phosphonous acid compounds in which two to four benzene nuclei are bound together and which contain one to three phosphorus atoms. The new compounds are free acids, their salts with inorganic cations, their esters, thioesters or amides. The invention concerns also the manufacture of these benzene phosphonous acid compounds and their use for the stabilization of organic materials.

Abstract: The present invention relates to the use of the known compound 4-(1-methyl-4-piperidylidene)-4H-benzo 4,5!cyclohepta 1,2-b!thiophen-10(9H )-one for the prevention and treatment of allergic conditions such as allergic asthma.

Abstract: The invention concerns a novel catheter for placement in an artery, vein or fistula vessel of a patient, through which blood may be withdrawn or delivered to the patient, which comprises a catheter wall, the inside surface of which defines a lumen having a cross-sectional area in a proximal end region of the catheter which is larger than the cross-sectional area of the lumen defined in a distal end region of the catheter, at least one opening being provided in the wall of the catheter in the region of its distal end through which blood may be passed.Various catheter assemblies employing a catheter such as described above are disclosed.

Abstract: The compounds are 4-aryl substituted buta-2,3-dienoic acids and esters thereof which may also be lower alkyl-substituted at any of the 2- and 4- positions, e.g., 4-(p-methoxyphenyl)-2-methyl-buta-2,3-dienoic acid. The compounds are useful as pharmaceuticals, e.g., as antiinflammatory agents and hypolipidemic agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R is lower alkyl or cycloalkyl of 3 to 7 carbon atoms; cycloalkyl of 3 to 7 carbon atoms substituted by alkyl of 1 to 4 carbon atoms; .alpha.-dialkylpropinyl or .alpha.-dialkylallyl of 5 to 9 carbon atoms; hydroxyalkyl of 2 to 7 carbon atoms, the hydroxy group thereof being separated by at least two carbon atoms from the nitrogen atom to which R is bound; phenethyl; phenethyl substituted by halogen, alkyl or alkoxy of 1 to 4 carbon atoms; or adamantyl,R.sub.1 is hydrogen, halogen, alkyl or alkoxy of 1 to 4 carbon atoms, trifluoromethyl in the 5, 6 or 7 position, or a nitro or A--NH-- group in the 4 or 5 position, wherein A is formyl or alkanoyl of 2 to 4 carbon atoms, andR.sub.2 is hydrogen, or, when R.sub.1 is alkyl of 1 to 4 carbon atoms, also alkyl of 1 to 4 carbon atoms, or, when R.sub.

Abstract: Disclosed are basic dyes, e.g., azo dyes and anthraquinone dyes free from sulphonic acid groups and which contain, as characteristic group, a group of the formula ##STR1## in which R and R.sub.1, independently, are substituted or unsubstituted C.sub.1-4 alkyl or are linked to form a ring, orOne of R and R.sub.1 is --NH.sub.2 or C.sub.1-4 alkoxy, the other substituted or unsubstituted alkyl,R.sub.2 and R.sub.3, independently, are hydrogen or C.sub.1-4 alkyl,Y is a bridging group,Q is unsubstituted or substituted phenyl, biphenylyl, naphthyl or ##STR2## in which R.sub.7 is ##STR3## where R.sub.8 ic C.sub.1-4 alkyl, andA.sup.- is an anion. These dyes are useful for the dyeing and printing of polymers and copolymers of acrylonitrile and asymmetrical dicyanoethylene as well as polyesters and polyamides modified to contain acid groups. The dyes build-up well and exhibit good pH stability and stability to boiling.

Abstract: Disclosed are compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, carboxy, alkoxycarbonyl, aminocarbonyl, mono- or dialkylaminocarbonyl, benzimidazolonyl-5-aminocarbonyl or phenylaminocarbonyl, the phenyl radical of which is unsubstituted or substituted by up to 3 substituents selected from up to 3 from chlorine, bromine and methyl and up to 2 from cyano, nitro, methoxy, ethoxy and trifluoromethyl,R.sub.2 is hydrogen, halogen, alkoxy or nitro, andR.sub.3 and R.sub.4 are, independently, hydrogen, halogen, nitro, alkyl, alkoxy, alkoxycarbonyl, aminocarbonyl, mono- or dialkylaminocarbonyl, phenylaminocarbonyl, alkylcarbonylamino, alkoxycarbonylamino, benzoylamino or benzylcarbonylamino,Their production and use as pigments for plastics, paper, paints, varnishes, spin dyeing of cellulose acetate, textile coating and pigment printing.

Abstract: The invention concerns novel compounds of the formula: ##STR1## wherein n is 1, 2 or 3 R.sub.1 is lower alkylR.sub.2 is hydrogen or lower alkyl andA is a tricyclic moiety,Useful as sedative-neuroleptic, muscle-relaxant and sleep-promoting agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R is alkyl of 3 to 7 carbon atoms or cycloalkyl of 3 to 7 carbon atoms, cycloalkyl of 3 to 7 carbon atoms monosubstituted by alkyl of 1 to 4 carbon atoms, .alpha.-dialkylpropynyl of 5 to 9 carbon atoms or .alpha.-dialkyl-allyl of 5 to 9 carbon atoms, hydroxyalkyl of 2 to 7 carbon atoms or phenoxyalkyl of 8 to 11 carbon atoms, the oxygen atom of the last two radicals being separated by at least two carbon atoms from the nitrogen atom to which R is bound,R.sub.1 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2,3,6 or 7 position, orIi. chlorine or bromine, in the 2, 3 or 7 position,Iii. nitro or --NHA wherein A is alkanoyl of 1 to 4 carbon atoms, in the 2, 3 or 7 position, orIv. fluorine, cyano or COOB, wherein B is alkyl of 1 to 4 carbon atoms, in the 2 or 3 position, andR.sub.2 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2, 3, 6 or 7 position,Ii. chlorine or bromine, in the 2, 3 or 7 position, orIii.

Abstract: Anti-inflammatories and analgesics of the formula: ##STR1## wherein R.degree. is alkyl, R is hydrogen, alkyl, halo, nitro or R"' OOC--, R' is hydrogen, alkyl or halo, R" is a hydrolyzable carboxylic acid acyl group and R"' is hydrogen or alkyl.

Abstract: Substituted aminophenyl ketones such as 2-alkylaminobenzophenones are prepared by reacting a corresponding 2-aminophenyl ketone with a ketone or aldehyde, a borohydride and strong acid.

Abstract: DISCLOSED is a process for the production of paper and paper-like products which comprises the step of incorporating in the pulp a retention agent comprising a polyalkylene oxide of molecular weight in excess of 1 million and a phenol- or naphthol-formaldehyde or -sulphur resin.

Abstract: Anti-allergic 2-amino-quinolin-4-one-3-phosphonic acid esters are prepared by reacting an isatoic anhydride with the carbanion resulting from the treatment of an organo-methane phosphate with a proton abstracting agent.

Abstract: This invention provides compounds of formula I, ##STR1## wherein R is alkyl of 3 to 7 carbon atoms; cycloalkyl of 3 to 7 carbon atoms; cycloalkyl of 3 to 7 carbon atoms monosubstituted with alkyl of 1 to 4 carbon atoms; .alpha.-dialkylpropinyl of 5 to 9 carbon atoms; .alpha.-dialkylallyl of 5 to 9 carbon atoms; hydroxyalkyl of 2 to 7 carbon atoms, the hydroxy group thereof being separated by at least two carbon atoms from the nitrogen atom to which R is bound; phenethyl; phenethyl mono- or disubstituted in the phenyl residue independently when di-substituted with halogen of atomic number from 9 to 35, alkyl of 1 to 4 carbon atoms or unbranched alkoxy of 1 to 4 carbon atoms; or adamantyl; andEither R.sub.1 is phenyl and R.sub.2 is hydrogen;Or R.sub.1 is alkyl of 1 to 4 carbon atoms or halogen of atomic number from 9 to 35 and R.sub.

Abstract: Compounds of the formula ##STR1## wherein R and R.sup.o are lower alkyl, R' is optionally substituted phenyl or 2-thienyl and n is 0 to 2, and their salt forms, are prepared by reacting a compound of the formula: ##STR2## with an aromatic nitrile and strong base, and quenching with water when the free base form is desired, said first mentioned compounds being intermediates for quinazolinones.

Abstract: Hypolipidemic agents of the formula: ##STR1## wherein X is C.dbd.O or CHOH,R.degree. is branched lower alkyl,R is hydrogen, alkyl, or halo,n is 1 or 2, andR' and R" are hydrogen, halo, alkyl or alkoxy, e.g., 4-phenoxy-pivalophenone.

Abstract: Disclosed are azo dyes of the formula ##STR1## wherein R.sub.1 is an aliphatic or aryl group,R.sub.2 is cyano, alkoxycarbonyl or substituted alkoxycarbonyl,R.sub.3 is an aliphatic or aryl group, andK is a coupling component radical,The synthesis thereof and the use thereof for the dyeing and printing of textile and non-textile substrates. The disclosed disperse dyes are useful for dyeing and printing synthetic and semi-synthetic, hydrophobic, high molecular weight materials such as linear aromatic polyesters, polyamides, cellulose 21/2 acetate and cellulose triacetate. The obtained dyeings have satisfactory fastness properties, particularly fastness to light, thermofixation, sublimation and pleating.

Abstract: The immunogenic components from influenze viruses are isolated by selectively solubilizing the component in an aqueous media with a cationic detergent.

Abstract: Hydroxymethyl-substituted-2(1H)-quinazolinones, e.g., 7-hydroxymethyl-1-isopropyl-4-phenyl-2(1H)-quinazolinone, are useful as anti-inflammatory agents.