Abstract: A variable embedding method, for solving a large-scale problem using dedicated hardware by dividing variables of a problem graph into partial problems and by repeating an optimization process of the partial problems when an interaction of the variables of an optimization problem is expressed in the problem graph, includes: determining whether a duplicate allocation of the variables of the optimization problem to the vertices of the hardware graph is required when embedding at least a part of all the variables into the vertices of the hardware graph; and selecting one of the variables requiring no duplicate allocation and embedding selected variable in one of the vertices of the hardware graph without using another one of the variables requiring the duplicate allocation as one of the variables of the partial problem.

Abstract: The present invention provides a vaccine composition for treating or preventing cancer expressing VASH2, containing a peptide including an amino acid sequence represented by SEQ ID NO: 4.

Abstract: System include an ultrasonic transducer configured to couple to a nondestructive testing (NDT) sample and configured to produce and direct an ultrasonic probe wave at a selected frequency into a subsurface region of the NDT sample, a 3D laser scanning vibrometer configured to direct a detection beam in a scan area on a surface of the NDT sample and to receive a return beam from the scan area, and to detect, based on the return beam, a 3D motion of the surface across a wideband frequency range, and a processor, and a memory configured with instructions that, when executed by the processor, cause the processor to produce sub-surface image data of the NDT sample at multiple harmonics of the selected frequency in the wideband frequency range based on the detected 3D surface motion, wherein the sub-surface image data describes a nonlinear defect response produced in the NDT sample by interaction of the ultrasonic probe wave with the subsurface region.

Abstract: A storage circuit includes: the array of a memory cell MC including a variable-resistance element; a conversion circuit that converts the resistance value of each memory cell into the signal level of an electric signal; a reference signal generation circuit that generates a reference signal common to a plurality of columns; a correction circuit that corrects one of the signal level of the reference signal and the signal level of the electric signal for each column of the array of the memory cell; and an RW circuit that determines data stored in the memory cell belonging to a corresponding column by comparing one of the reference level and the signal level of the electric signal, corrected by the correction circuit, and the other of the reference level and the signal level of the electric signal.

Abstract: The signal processing system generates image data, based on an electric signal group output from a radiation detector, and recognizes the electric signal group as a processing target, and the electric signal group includes at least part of an electric signal group meeting the following requirements: the electric signal group is an electric signal group with a signal value within a predetermined range, the electric signal group corresponding to a gamma ray with energy equal to or less than 375 keV; the predetermined range is equal to or greater than 50% and equal to or less than 80% relative to a 100% signal value; and the 100% signal value is a signal value detected when a gamma ray with energy of 511 keV enters a radiation detection element in the radiation detector and is totally absorbed by the radiation detection element.

Abstract: A method of treating a disease that is treatable through inhibition of at least one kinase selected from the group consisting of CDK7, CDK4, CDK6, PIM2, TSSK3, MST4, NEK6, MAP3K, MST3, DDR1, SPHK1, CaMK1, AurA, BRK, CaMK4, and PIM1, the method comprising administering an effective dose of a compound represented by the following formula (1) or a salt thereof to a patient:

Abstract: Provided is ITO particles satisfying a relationship expressed in Expression (1) given below. 16×S/P2?0.330 . . . (1) (In the expression, S indicates a particle area in a TEM photographed image, and P indicates a perimeter of the particle).

Abstract: To provide tissue paper excellent in softness and smoothness. In tissue paper that is two-ply non-moisturizing tissue paper to which no chemical solution is applied, a basis weight per sheet is 10.0 to 18.0 g/m2, the thickness of two plies is 100 to 240 ?m, a dry tensile strength in the paper horizontal direction is 70 to 180 cN/25 mm, a wet tensile strength in the paper horizontal direction is 25 to 55 cN/25 mm, and a free sensory evaluation value Ef calculated according to the following Equation 1 is 3.7 to 6.6, and a slip sensory evaluation value Es calculated according to the following Equation 2 is 5.0 to 8.2. Free sensory evaluation value Ef=?2.879×(dry tensile strength in paper horizontal direction)+6.55×(wet tensile strength in paper horizontal direction)+5.36??(Equation 1) Slip sensory evaluation value Es=?8.80×(dynamic friction coefficient)?0.41×(arithmetic mean surface roughness)+13.

Abstract: A method for producing a polyvalent alcohol ester compound, characterized in that a polyvalent alcohol compound and a carboxylic acid compound are allowed to react in the presence of an acidic solid catalyst swollen with the polyvalent alcohol compound or the carboxylic acid compound without using a solvent to selectively produce a monocarboxylic acid ester or a polycarboxylic acid ester of a polyvalent alcohol. In this manner, a mono-fatty acid ester and a poly-fatty acid ester (e.g., di-fatty acid ester) of a polyvalent alcohol can be selectively and effectively produced from a polyvalent alcohol compound and a fatty acid compound.

Abstract: The high-potential pluripotent stem cells of the present invention not only have characteristics of conventional Muse cells, namely, are capable of differentiating into any embryonic tissue serving as all cells constituting the body, but also are capable of differentiating into any extraembryonic tissue cells such as placenta and/or germline cells, namely, have differentiation capacities close to totipotency. Thus, the high-potential pluripotent stem cells not only allow for conventional regenerative therapies of various diseases which cause any damage in constitution of the body, but also are capable of differentiating into any extraembryonic tissue cells such as placenta, and thus can allow any damaged sites in such any extraembryonic tissue to be re-constituted, resulting in improvement or restoring of the function of such any damaged sites, and can be applied to a new field of regenerative therapy, for example, can be used in reproductive therapies such as fertility therapy.

Abstract: A STAT3 phosphorylation inhibitor containing stanniocalcin 1 (STC1) as an active ingredient. A JAK expression or phosphorylation inhibitor containing stanniocalcin 1 as an active ingredient. A prophylactic or therapeutic agent for autoimmune disease, the agent containing stanniocalcin 1 as an active ingredient. A prophylactic or therapeutic agent for influenza virus infection, the agent containing stanniocalcin 1 as an active ingredient. A prophylactic or therapeutic agent for coronavirus infection, the agent containing stanniocalcin 1 as an active ingredient.

Abstract: Provided is an X-type 3-terminal STT-MRAM (spin orbital torque magnetization reversal component) having a high thermal stability index ? and a low writing current IC in a balanced manner. A magnetoresistance effect element has a configuration of channel layer (1)/barrier layer non adjacent magnetic layer (2b)/barrier layer adjacent magnetic layer (2a)/barrier layer (3).

Abstract: A cell or tissue embedding device having an aqueous gel serving as an immunoisolation layer, the aqueous gel containing, as components thereof, a denatured polyvinyl alcohol resin having an activated carbonyl group and a crosslinking agent is highly capable of supplying a physiologically active substance.

Abstract: An object to be achieved by the present in is to prepare a droplet using a protein that has not been known heretofore to form a droplet. The present invention provides a droplet including an assembly of a protein, wherein the protein is a PDI family protein and/or an artificial protein, and contains a thioredoxin-like domain.

Abstract: A method for detecting a neurodegenerative disease in a subject, the method including: measuring levels of two biomarkers including FABP3 and FABP5 in a biological sample from a subject.

Abstract: An optical connector ferrule, an optical connector, and a composite fiber connecting assembly are provided. The optical connector ferrule includes a stationary ferrule having a first through-hole, a composite fiber, and a connecting ferrule having a second through-hole. The composite fiber includes a first optical fiber and a signal wire, and is placed in the first through-hole in the stationary ferrule. The connecting ferrule includes a conductive path. The stationary ferrule has a second end face abutting a third end face of the connecting ferrule. The first optical fiber has an end connected to an end of the second through-hole. The signal wire and the conductive path are connected to each other.

Abstract: A method for producing a TiAl alloy member includes a molding step (S10) of laminating a solidified body obtained by melting and solidifying or sintering powder of a TiAl alloy by irradiation of the powder with a beam, to mold a laminated body; and a heat treatment step (S12) of heating the laminated body at a setting temperature that is equal to or higher than a temperature at which a phase transformation to an ? phase is initiated, to produce a TiAl alloy member. By the method for producing a TiAl alloy member, the TiAl alloy member can be easily molded with a decrease in high temperature properties suppressed.

Abstract: A three-dimensional shape measuring method includes: a first step to: project first and second projection images on a target object, wherein the first projection images include row-direction stripe patterns different from each other, and the second projection images include column-direction stripe patterns different from each other, and obtain first and second captured images of the target object, wherein the first captured images are captured while the first projection images are projected, and the second captured images are captured while the second projection images are projected; a second step to identify a corresponding projection pixel of the first and second projection images, wherein the corresponding projection pixel corresponds to each of captured pixels of the first and second captured images; and a third step to identify a 3D shape of the target object based on a result of the second step.

Abstract: The present disclosure provides a method for producing a polyisoprenoid, which makes it possible to synthesize in vitro a polyisoprenoid having an unprecedented structure, such as a 100% cis-polyisoprenoid or a polyisoprenoid containing an allylic diphosphate derivative as an initiating terminal. The present disclosure relates to a method for producing a polyisoprenoid in vitro, which employs a gene coding for a neryl diphosphate synthase and rubber particles bound to a protein encoded by the gene, or a method for producing a polyisoprenoid, which includes introducing into a plant a vector in which a gene coding for a neryl diphosphate synthase is linked to a promoter having a promoter activity that drives laticifer-specific gene expression to express a protein encoded by the gene specifically in laticifers.

Abstract: Gallium-doped zinc oxide particles having an average particle diameter of from >0 nm to 30 nm and a resistivity of from 0.08 M?·cm to 1.4 M?·cm.