Abstract: Described herein are crosslinked alkylated poly(benzimidazole) and poly(imidazole) polymer materials and devices (e.g., fuel cells, water electrolyzers) including these polymer materials. The polymer materials can be prepared in a convenient manner, allowing for applications such as anion exchange membranes (AEMs). The membranes provide high anion conductivities over a wider range of operating conditions when compared to the analogous membranes that are not cross-linked. The crosslinked polymer materials have improved alkaline stability, when compared to the analogous non-crosslinked polymer materials.
Type:
Application
Filed:
August 1, 2017
Publication date:
June 6, 2019
Applicant:
Simon Fraser University
Inventors:
Steven Holdcroft, Thomas Weissbach, Timothy James Peckham, Andrew Wright, Benjamin Britton
Abstract: A TEM line to double-ridged waveguide launcher and horn antenna are disclosed. The launcher uses multiple probes or one or more wide-aspect probes across the ridge gap to minimize spreading inductance and a TEM combiner or matching taper to match the impedance of the probes over a broad bandwidth. The horn uses a power-law scaling of gap height relative to the other dimensions of the horn's taper in order to provide a monotonic decrease of cutoff frequencies in all high-order modes. Both of these techniques permit the implementation of ultra-wideband designs at high frequencies where fabrication tolerances are most difficult to meet.
Abstract: Peptide-based neurokinin antagonists of fish reproduction are disclosed. Compositions comprising antagonists of fish neurokinin and methods of inhibiting or delaying puberty, fish maturation or reproduction processes using these compounds are also provided.
Type:
Application
Filed:
October 30, 2018
Publication date:
June 6, 2019
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided.
Type:
Application
Filed:
December 5, 2018
Publication date:
June 6, 2019
Applicants:
Mayo Foundation for Medical Education and Research, University of Leeds
Inventors:
Richard G. Vile, Timothy J. Kottke, Jill M. Thompson, Jose S. Pulido, Alan A. Melcher, Peter Selby
Abstract: The present inventors tried to prepare a knock-in animal using a genome editing system containing a nuclease in the form of protein and a DNA-targeting RNA and using a single-stranded DNA as a donor, and found that it is possible to obtain a cell in which the donor DNA has been knocked in with extremely high efficiency.
Type:
Application
Filed:
August 1, 2017
Publication date:
June 6, 2019
Applicant:
National University Corporation Tokyo Medical and Dental University
Abstract: The present disclosure relates to a bimetal-conductive polymer Janus composite nanostructure having electrical stimulation responsiveness, a colloidal self-assembled structure thereof, a preparation method thereof and biosensing, bioimaging, drug delivery and industrial application using the same.
Type:
Application
Filed:
August 9, 2017
Publication date:
June 6, 2019
Applicant:
Industry-University Cooperation Foundation Hanyang University Erica Campus
Abstract: A support (26) for a tablet (22) for use in a Functional Magnetic Resonance Imaging (fMRI) machine (12) is provided. The support (26) includes a plurality of curved braces (80, 82) configured to mount within a bore (16) of the fMRI machine (12); a channel (90) coupled to one end of the curved braces (80, 82); and a pair of lower braces (86) coupled to another end of the curved braces (80, 82); wherein the channel (90) includes a C-shaped opening (108) configured to receive a mounting bracket (24) coupled to the tablet (22).
Type:
Application
Filed:
August 3, 2017
Publication date:
June 6, 2019
Applicant:
Indiana University Research and Technology Corporation
Abstract: Provided is a medicament comprising the compound represented by the following general formula (1) or a salt thereof: In the formula, R1, R2, R3, R4, R5, X1, X2, and X3 are defined. Methods for producing various radioactive compounds are also provided.
Type:
Application
Filed:
December 6, 2018
Publication date:
June 6, 2019
Applicants:
NIHON MEDI-PHYSICS CO., LTD., Kyoto University, National Hospital Organization
Abstract: Systems, devices, and methods for proportionally balancing power during wireless communication are provided. The disclosures provide for an integrated radio in which the functionality of an active radio and a passive radio are integrated into a single radio, with the active and passive radios each being configured to operate in three different modes: active, passive, and backscatter. Based on power and communication link information, the integrated rode is able to balance the modes at which the two radios are operated, thereby optimizing power consumption of the device into which the integrated radio is incorporated. The resulting systems, devices, and methods lead to ultra-low power consumption that enables these communication techniques to enhance computing devices from smartwatches to laptops. Devices incorporating the integrated radios, and methods for power-proportionally exchanging data, among other systems, devices, and methods, are also provided.
Abstract: The invention belongs to the fields of medicine and immunology, particularly, the field of immunological diagnosis. In particular, the invention discloses a method for assessing whether a subject is at risk of developing human cytomegalovirus (HCMV) active infection and a kit therefore. The method comprises the steps of: (1) determining the level of an antibody against a HCMV protein in a body fluid sample from the subject; and (2) comparing the level with a predetermined reference value, wherein if the level is below the predetermined reference value, the subject is determined to be at risk of developing HCMV active infection. In addition, the invention also discloses a method for screening a candidate drug which is capable of improving the ability of a subject to resist human cytomegalovirus (HCMV) active infection, and a kit therefore.
Type:
Grant
Filed:
January 26, 2016
Date of Patent:
June 4, 2019
Assignee:
Xiamen University
Inventors:
Shengxiang Ge, Jinjie Li, Xi Huang, Tingdong Li, Jun Zhang, Ningshao Xia
Abstract: A method of regulating body temperature that involves (i) determining, via processing circuitry, if sensor data from a plurality of sensors is in a predetermined normal range, (ii) converting the sensor data to fuzzy values when the sensor data is not in the predetermined normal range, (iii) combining one or more related consequents of the predetermined fuzzy rules, (iv) evaluating the combined consequents to determine a centroid value using a centroid method; and (v) transmitting the centroid value to a thermal management system to activate the thermal management system to a predetermined activation level based on the centroid value, wherein the plurality of sensors include a core temperature sensor, a skin temperature sensor, a skin blood flow sensor, a cardiac output sensor, a neuromuscular activity output sensor, an electromyography sensor, a vibration sensor, and an imaging device.
Type:
Grant
Filed:
October 31, 2018
Date of Patent:
June 4, 2019
Assignees:
National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
Abstract: Provided are methods and kits for reducing the severity of muscle stiffness. The method comprises delivering to one or more specific locations in the deep fascia of an affected muscle a composition comprising a therapeutically effective amount of hyaluronidase.
Abstract: Embodiments of solid-state stress sensors are presented herein. A sensor system may include a substrate, a first layer of sensing material disposed on a first surface of the substrate, and at least three electrodes forming a first and second electrode pair. The at least three electrodes may include a first electrode, a second electrode, and a third electrode. The first electrode may be disposed in a first plane and the second electrode and the third electrode may be disposed in a second plane, the first and second planes associated with a first direction parallel to the first surface. The first and second electrodes may be at least partially offset in the first direction. The first and third electrodes may be at least partially offset in the first direction. The sensor system may be configured to generate an output signal in response to a shear stress within the sensing material.
Type:
Grant
Filed:
July 15, 2016
Date of Patent:
June 4, 2019
Assignees:
Silicon Audio, Inc., Board of Regents of the University of Texas System
Inventors:
Neal A. Hall, Donghwan Kim, Randall P. Williams, David P. Gawalt, Bradley D. Avenson, Caesar T. Garcia, Kristofer L. Gleason
Abstract: An element recovery method and an element recovery apparatus are provided by which an element containing a high-purity rare earth element can be recovered at low cost. The element recovery method includes the steps of: preparing molten salt containing a rare earth element; and controlling electric potentials in a pair of electrode members at prescribed values while keeping the pair of electrode members in contact with the molten salt, thereby depositing the rare earth element existing in the molten salt on one of the pair of electrode members. In this way, as compared with the conventional wet separation method, an element such as a rare earth element that is to be recovered can be directly recovered from the molten salt in which the element is dissolved, so that the steps of the recovery method can be simplified and reduced in cost.
Type:
Grant
Filed:
August 8, 2012
Date of Patent:
June 4, 2019
Assignees:
Sumitomo Electric Industries, Ltd., Kyoto University
Abstract: Provided is a real-time imaging method of NAPDH-dependent metabolic activity in a cell and a use thereof, and more particularly, an imaging method capable of measuring concentration gradient and change in an intracellular coenzyme using a mutant of metagenome-derived blue fluorescent protein (mBFP) in real-time and an application method thereof. In particular, the method of imaging and quantifying the coenzyme contained in various biological samples may be performed by improving fluorescence in a short time even under anaerobic conditions, without adding a substrate required for coenzyme measurement or conversion without destroying cells, and without consuming the time required for formation of a special structure (fluorophore) for generating fluorescence unlike the existing quantitative systems.
Type:
Grant
Filed:
September 14, 2018
Date of Patent:
June 4, 2019
Assignee:
Industry Foundation of Chonnam National University
Inventors:
Geun-Joong Kim, Eung Sam Kim, Jeong Sun Kim, Sung Hwan You, Dae Eun Cheong, Eun Seo Jo
Abstract: Some aspects of the present disclosure relate to systems and methods for free-breathing cine DENSE MRI using self-navigation. In one embodiment, a method includes acquiring magnetic resonance data for an area of interest of a subject, wherein the acquiring comprises performing sampling with phase-cycled, cine displacement encoding with stimulated echoes (DENSE) during free-breathing of the subject; identifying, from the acquired magnetic resonance data, a plurality of phase-cycling data pairs corresponding to matched respiratory phases of the free-breathing of the subject; reconstructing, from the plurality of phase-cycling data pairs, a plurality of intermediate self-navigation images; performing motion correction by estimating, from the plurality of intermediate self-navigation images, the respiratory position associated with the plurality of phase-cycling data pairs; and reconstructing a plurality of motion-corrected cine DENSE images of the area of interest of the subject.
Type:
Grant
Filed:
April 21, 2017
Date of Patent:
June 4, 2019
Assignee:
University of Virginia Patent Foundation
Inventors:
Xiaoying Cai, Frederick H. Epstein, Xiaodong Zhong
Abstract: A disinfectant appliance has a plurality of chlorite absorbent particles, a plurality of redox resin particles, and at least one absorbent material combined such that the absorbent material allows and can promote: infusion of water into the disinfectant appliance; release of the chlorite from the chlorite absorbent particles into the water to form a chlorite comprising solution; contacting of the chlorite comprising solution with the redox resin particles; and the expulsion of ClO2 comprising solution from the disinfectant appliance onto a surface to be disinfected. The disinfectant appliance can include a storage section and can include a handle. The disinfectant appliance can be in the form of a wipe or sponge that can be contacted with a surface suspected of being infected.
Type:
Grant
Filed:
June 11, 2015
Date of Patent:
June 4, 2019
Assignee:
University of Florida Research Foundation, Inc.
Abstract: The invention provides nucleic acids and nucleic acid expression vectors containing optimized mGluR6 promoters for expression of transgenes in the retina. The compositions and methods of the invention are useful for expression of gene products to preserve, improve, or restore phototransduction or vision.
Type:
Grant
Filed:
March 11, 2015
Date of Patent:
June 4, 2019
Assignee:
Wayne State University
Inventors:
Zhuo-Hua Pan, Qi Lu, Tushar H. Ganjawala, JrGang Cheng
Abstract: The systems and methods described herein are directed towards a solid state pumping system that utilizes an electric field applied across a channel formed within the solid state pump to move electro-rheological (ER) fluid from an inlet fluidly coupled to a first end of the channel to an outlet fluidly coupled to a second end of the channel. The solid state pumping system may include first, second and third plate with the second plate disposed between the first and third plate. The second plate may include a channel having first and second circuits coupled to opposing sides of the channel. In an embodiment, in response to a voltage applied thereto, the first and second circuits can provide an electric field voltage across the channel such that in response to the electric field voltage the ER fluid moves from the first end to the second end of the channel.
Type:
Grant
Filed:
October 18, 2016
Date of Patent:
June 4, 2019
Assignees:
Massachusetts Institute of Technology, Utah State University
Inventors:
Youzhi Liang, Anette E. Hosoi, Matthew F. Demers, Karl D. Iagnemma, Jose R. Alvarado, Regan A. Zane, Michael Evzelman
Abstract: The present application relates to a sensing method that is carried out using an electrode that comprises an electrode substrate functionalized with sensing elements. The method involves conducting electrochemical impedance spectroscopy at a plurality of applied voltages and then integrating measurement data as a function of voltage. Also provided is an apparatus for carrying out the sensing method. The method and apparatus are suitable for a broad range of sensing applications, including the detection of diagnostic biomarkers, drug screening, development of glycoarray systems and the sensing of environmental parameters such as light intensity, temperature and humidity.
Type:
Grant
Filed:
July 6, 2017
Date of Patent:
June 4, 2019
Assignees:
Oxford University Innovation Limited, Universidade Estadual Paulista “Julio de Mesquita-Filho”—UNESP