Abstract: Methods, apparatuses, and systems for organizing data delivering unmanned aerial vehicles (UAVs) are provided. Inter-cluster coordinators can organize data delivering unmanned aerial vehicle base stations (UAV-BSs). Various beamforming techniques (e.g., LZFBF and ZFBF) can be incorporated, and the inter-cluster coordinator can operate on a base station that serves as a controlling network node.
Type:
Grant
Filed:
October 28, 2016
Date of Patent:
June 4, 2019
Assignee:
The Florida International University Board of Trustees
Inventors:
Nadisanka Rupasinghe, Ismail Guvenc, Ahmed Salah Ibrahim Mohamed
Abstract: This document describes techniques and devices for type-agnostic radio frequency (RF) signal representations. These techniques and devices enable use of multiple different types of radar systems and fields through type-agnostic RF signal representations. By so doing, recognition and application-layer analysis can be independent of various radar parameters that differ between different radar systems and fields.
Type:
Grant
Filed:
April 29, 2016
Date of Patent:
June 4, 2019
Assignees:
Google LLC, The Board of Trustees of the Leland Stanford Junior University
Inventors:
Jaime Lien, Patrick M. Amihood, Ivan Poupyrev
Abstract: Disclosed herein are methods and compositions for generating cultures and isolated cell populations containing preplacodal ectoderms cells, otic placode cells, and inner ear sensory hair cells derived from pluripotent cells by modulating TGF?, BMP, and FGF signaling pathways under defined culture conditions. Also described are methods for obtaining non-otic placodal tissues from pluripotent stem cells. Methods for identifying agents that induce or enhance differentiation and generation of hair cells are also disclosed. Methods for identifying cytoprotective agents for hair cells are also described.
Type:
Grant
Filed:
March 1, 2017
Date of Patent:
June 4, 2019
Assignee:
Indiana University Research & Technology Corporation
Inventors:
Eri Hashino, Gerry Oxford, Karl R. Koehler
Abstract: A method for improving photosynthesis of rice includes the step of knocking out IPS1 gene in rice. The IPS1 gene has a nucleotide sequence shown in SEQ ID NO: 1.
Abstract: The invention provides compositions and methods for treating diseases associated with expression of EGFRvIII. The invention also relates to chimeric antigen receptor (CAR) specific to EGFRvIII, vectors encoding the same, and recombinant T cells comprising the anti-EGFRvIII CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an anti-EGFRvIII binding domain.
Type:
Grant
Filed:
June 15, 2016
Date of Patent:
June 4, 2019
Assignees:
Novartis AG, The Trustees of the University of Pennsylvania, University of Pittsburgh—of The Commonwealth System of Higher Education
Inventors:
Jennifer Brogdon, Laura Alexandra Johnson, Carl H. June, Andreas Loew, Marcela Maus, John Scholler, Hideho Okada
Abstract: A super-amphiphobic composite material and use of the same as an inhibitor, lubricant, reservoir protectant, and accelerator in water-based drilling fluids. A method for preparing the amphiphobic composite material includes: performing a first mixing of nano-titanium dioxide and nano-silicon dioxide in an alcohol-water mixed solvent under an alkaline condition, to obtain a dispersion of nano-titanium dioxide and nano-silicon dioxide; then introducing a fluorosilicone-containing coupler into the dispersion of nano-titanium dioxide and nano-silicon dioxide and performing a second mixing. The amphiphobic composite material may be applied in water-based drilling fluids. It has an effect of strongly inhibiting hydrated swelling and disintegration, low toxicity and high compatibility; can solve problems such as well wall instability, blockage of drilling tools, and reservoir damage, etc.
Type:
Grant
Filed:
January 25, 2019
Date of Patent:
June 4, 2019
Assignee:
China University of Petroleum (Beijing)
Inventors:
Guancheng Jiang, Xiaoxiao Ni, Lili Yang, Guangchang Ma, Chunyao Peng, Deli Gao, Xi Wang, Jinsheng Sun, Xiaolin Pu, Kai Wang, Zhengqiang Deng, Yang Bai, Yinbo He, Xinliang Li
Abstract: Catalysts useful in transforming biomass to bio-oil are disclosed, as are methods for making such catalysts, and methods of transforming biomass to bio-oil. The catalysts are especially useful for, but are not limited to, microwave- and induction-heating based pyrolysis of biomass, solid waste, and other carbon containing materials into bio-oil. The catalysts can also be used for upgrading the bio-oil to enhance fuel quality.
Type:
Grant
Filed:
June 21, 2018
Date of Patent:
June 4, 2019
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Provided herein are methods of making a biomimetic hydrogel scaffold comprising a polycation and a polyanion. Also provided are anisotropic biomimetic hydrogel scaffold compositions suitable for use in tissue growth, including bone, muscle, and nerve growth an optionally comprising a carbon allotrope such as graphene. Also provided are methods of producing tissue comprising growing tissue on the biomimetic hydrogel scaffold comprising a polycation and a polyanion.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
June 4, 2019
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Abstract: A renewable energy-based hybrid bi-directionally interactive DC traction power supply system includes two traction substations. Each substation includes transformers, rectifiers, bidirectional AC-DC converters, a DC bus, a catenary, a steel rail and a section post. A DC bus between two adjacent traction substations is provided with a DC renewable energy system constructed by an electric vehicle charging-discharging system, a distributed generation and more than one low voltage DC microgrid. The DC renewable energy system is connected to the DC bus between two adjacent traction substations through a high voltage DC bus, thus a DC circular microgrid being formed in a power supply section post. The electric vehicle charging-discharging system is formed by more than one bidirectional DC-DC charging-discharging equipments which are intended for in connection with the power batteries of the electric vehicle.
Type:
Grant
Filed:
July 26, 2014
Date of Patent:
June 4, 2019
Assignees:
State Grid Corporation of China, North China Electric Power University, State Grid Liaoning Electric Power Company Limited Economic Research Institute
Inventors:
Ming Meng, Jian Liu, Xiping Wang, Dalong Hu, Li Jiang, Yingwei Song, Yan Liu, Liaoyi Ning
Abstract: A vibration energy harvester includes: a pair of electrodes provided so as to face opposite each other, with at least one of the pair of electrodes allowed to move; and an ion gel provided between the pair of electrodes, which is formed by using an ionic liquid, wherein: as an external vibration causes the electrode to move along a direction in which a distance between the pair of electrodes changes, power is generated through a change in an area of an electric double layer formed on two sides of an interface of each electrode and the ion gel.
Type:
Grant
Filed:
January 14, 2016
Date of Patent:
June 4, 2019
Assignees:
The University of Tokyo, Saginomiya Seisakusho, Inc., Central Research Institute of Electric Power Industry
Inventors:
Hiroyuki Fujita, Hiroyuki Mitsuya, Shimpei Ono
Abstract: Disclosed herein are crosslinked polycarbonates, composition thereof and methods thereof. The crosslinked polycarbonates can be prepared from allyl or epoxy polycarbonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Abstract: A system and method for enabling set up of a controlling device capable of controlling a plurality of appliances, via an interactive instruction set and associated programming. The programming is accessible by a STB or other controllable appliance and is configured to appropriately display interactive instructions and prompts to a user during a user initiated set up procedure for configuration of another controllable device (e.g., DVD, VCR, DVR, etc) available to the user. Appropriate set up data, generally in the form of command library codes, is displayed to the user by the interactive instruction set and associated programming for entry and trial by the user in set up of the desired appliance(s).
Type:
Grant
Filed:
December 15, 2017
Date of Patent:
June 4, 2019
Assignee:
Universal Electronics Inc.
Inventors:
Joseph Lee Haughawout, Patrick H. Hayes
Abstract: A floating gate based sensor apparatus includes at least two separate electrical bias components with respect to a floating gate based sensor surface within the floating gate based sensor apparatus. By including the at least two electrical bias components, the floating gate based sensor apparatus provides enhanced capabilities for biomaterial and non-biomaterial detection and manipulation while using the floating gate based sensor apparatus.
Abstract: This disclosure provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
Type:
Grant
Filed:
August 16, 2016
Date of Patent:
June 4, 2019
Assignee:
The Regents of the University of California
Abstract: Disclosed herein is a functionalized eyewear device that is adapted for collecting and analyzing disease biomarkers. Specifically, exemplified is a contact lens that has aptamer molecules associated therewith for binding to a specific biomarker (or biomarkers). The eyewear device is useful for detecting and diagnosing medical conditions.
Type:
Grant
Filed:
August 21, 2015
Date of Patent:
June 4, 2019
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Methods and apparatus are provided for performing back-reflection energy-dispersive X-ray diffraction (XRD). This exhibits extremely low sensitivity to the morphology of the sample under investigation. As a consequence of this insensitivity, unprepared samples can be analyzed using this method. For example, in a geological context, whole rock samples become amenable to analysis. A composite diffraction spectrum can be produced using information from different recorded spectra in different energy sub-ranges. The composite spectrum excludes fluorescence signals that would otherwise obscure the diffraction signals.
Abstract: An information management system includes: a mobile communication terminal capable of obtaining location information; and a medical institution provided with a regional medical data bank system and a transmitter. The mobile communication terminal transmits a space-time tag and a terminal ID to the system. The space-time tag is constituted of time information and location information. A space-time ID information processing unit of the system generates a space-time ID in a folder for each user based on a plurality of space-time tags and stores it in space-time ID information DB. A terminal device of the medical institution transmits the location information of the mobile communication terminal and the time information to the system. A verification processing unit verifies information from the mobile communication terminal against information from a utilization terminal and transmits the information to the utilization terminal when a request for transmission of the information is valid.
Type:
Grant
Filed:
November 19, 2014
Date of Patent:
June 4, 2019
Assignees:
GNSS Technologies Inc., Jichi Medical University
Abstract: This invention is about the compositions and methods for assessing and treating vascular endothelial dysfunction. Various aspects provide a method for treatment of vascular endothelial dysfunction, comprising administering a composition comprising nicotinamide mononucleotide and a pharmaceutical excipient to a subject. In one embodiment the dose is administered to subjects in response to the indicator. In another embodiment the dose is administered chronically to subjects.
Type:
Grant
Filed:
March 24, 2015
Date of Patent:
June 4, 2019
Assignee:
The Regents of the University of Colorado, a Body Corporate
Inventors:
Douglas R. Seals, Lindsey Gano, Natalie Poliektor
Abstract: In various embodiments, a device for inserting an implant on a human or animal body may be provided. The device may include an operable portion configured to make an incision on the human or animal body and configured to hold the implant for insertion on the human or animal body. The device may further include an actuator mechanism coupled to the operable portion, the actuator mechanism configured to move the operable portion along a first axis and configured to vibrate the operable portion along a second axis substantially perpendicular to the first axis.
Type:
Grant
Filed:
September 10, 2013
Date of Patent:
June 4, 2019
Assignee:
National University of Singapore
Inventors:
Kok Kiong Tan, Wenyu Liang, Phuong Pham Le, Sunan Huang, Hsueh Yee Lynne Lim, Chee Wee Gan
Abstract: The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
Type:
Grant
Filed:
July 11, 2018
Date of Patent:
June 4, 2019
Assignees:
The Regents of the University of California, University of Vienna, Emmanuelle Charpentier
Inventors:
Jennifer A. Doudna, Martin Jinek, Krzysztof Chylinski, Emmanuelle Charpentier