Abstract: Described herein are devices, compositions, and methods for improving color discernment.

Abstract: An emitter-detector pair sensor may be incorporated into a powered or electronic ophthalmic lens. The emitter-detector pair sensor may be configured to determine the distance from the sensor to an object in its path. Based upon this information, a system controller of the ophthalmic lens may output a signal to an actuator of the ophthalmic lens to control a variable power optic of the ophthalmic lens.

Abstract: A contact lens and a method for manufacturing thereof are provided. The contact lens has a silicone contact lens base material and an amorphous carbon film formed in the silicone contact lens base material. The amorphous carbon film of the contact lens is formed by subjecting the silicone contact lens base material to a plasma polymerization under an atmosphere of a mixed gas comprising a hydrocarbon gas and an oxygen-containing gas. The contact lens has excellent oxygen permeability and a high refractive index.

Abstract: Disclosed in this specification is a casting cup assembly comprising frontcurve and basecurve molds which of which includes a ring that circumscribes the respective concave and convex mold surface. When the casting cup is assembled, the rings align and minimize de-centering and tilting of the concave and convex mold surfaces which, in turn, reduces edge defects.

Abstract: Soft contact lens having regions of a material forming one or more higher modulus of elasticity zones in the peripheral region of the lenses add stiffness to the contact lenses. This increased stiffness in different zones or regions enable the contact lens to be more easily handled and make it less likely to fold in on itself.

Abstract: Multifocal contact lenses and methods and uses are described. The multifocal contact lenses include an optic zone. The optic zone has an aspheric power profile that provides a near vision refractive power and a distance vision refractive power, and provides an Add power that corresponds to the difference between the near vision refractive power and the distance vision refractive power. The multifocal contact lenses can improve binocular vision of presbyopic subjects by being prescribed such that the non-dominant eye contact lens is over-corrected for distance vision, and both multifocal contact lenses are under-corrected for the Add power requirement of the subject. Batches and sets of multifocal contact lenses are also described.

Abstract: A method of obtaining an impression of an eye, the method comprises preparing an impression material, contacting the impression material with an eye of a subject, obtaining an impression of the eye on the impression material, creating an indication of the orientation of the impression with respect to the eye, and removing the impression material from the eye. The impression can be used in a method of manufacturing a lens for an eye that comprises receiving one or more data files comprising a back lens surface calculation and a front lens surface calculation, forming a back lens surface from a lens blank based on the back lens surface calculation, forming a front lens surface from the lens blank based on the front lens surface calculation, and forming one or more asymmetric features in the back lens surface based on the back lens surface calculation.

Abstract: The present invention is directed to a composite lens, comprising an anterior rigid gas permeable layer, and an annulus of soft material bonded to a posterior surface of the anterior rigid gas permeable layer, wherein a central zone of the composite lens is rigid and without a soft layer, wherein a peripheral zone of the composite lens is generally rigid in its anterior aspect and soft in its posterior aspect.

Abstract: An eye-mountable device can include a transparent material and a substrate at least partially embedded in the transparent material. The transparent material can have a concave surface and a convex surface, with the concave surface configured to removably mount the eye-mountable device on a corneal surface overlaying a pupil. A light source can be disposed on the substrate and configured to emit light through the concave surface and towards the corneal surface such that the emitted light is viewable through the pupil. The light source can be controlled by circuitry disposed on the substrate. The circuitry can be configured to modulate the light emitted by the light source to provide modulated light.

Abstract: Provided herein is a computer program product comprising a non-transitory computer-readable medium storing an algorithm to optimize a wavefront guided correction for a custom ophthalmic lens. The correction is determined from inputs of quantified wavefront error and registration uncertainty and a metric predictive of a visual performance task of interest and provides a level of visual performance within a user-defined performance range. Also provided is a method for optimizing a wavefront guided correction for a custom ophthalmic lens via inputting residual wavefront error values and quantified translational and rotational movements into an algorithm configured to determine the optimal wavefront guided correction therefrom and a custom ophthalmic lens comprising the correction.

Abstract: An ophthalmic lens (1) has a concave front surface (2) and a convex rear surface, each of the front and rear surfaces comprising a central optical zone (4) which is surrounded by a peripheral zone (3). The ophthalmic lens (1) further comprises a unique lens identification code which is arranged in the peripheral zone (3) of one of said front and rear surfaces. The unique lens identification code has the form of an N×M dot matrix (5) comprising N rows and M columns of matrix elements (50), and the N×M dot matrix (5) represents a binary code.

Abstract: Method and apparatus for manufacturing a contact lens comprising: dispensing a plurality of separate portions (24) of a liquid composition onto a contact lens mold section (12, 16), each separate portion of the liquid composition having a volume of less than about 1000 nano-liters.

Abstract: The present invention provides a contact lens manufactured at least partially from an intelligent polymer, the lens having a relaxed state which, upon application of a first stimulus forms a first corrective shape and which, upon application of a second stimulus, forms a second corrective shape, wherein the corrective effect provided by the lens in the relaxed state is intermediate to the corrective visual effects provided by the first and second corrective shapes.

Abstract: A contact lens for use in controlling or retarding the progression of myopia in an eye has a central optical zone approximating the normal diameter of the pupil of the eye that gives clear central vision at distance for the wearer. An annular peripheral optical zone that is substantially outside the diameter of the pupil is formed around the central optical zone with greater refractive power than that of the central zone so that oblique rays entering the eye through the peripheral optical zone will be brought to focus at a focal plane that is substantially on or anterior to the peripheral region of the retina. Preferably, the rear surface of the lens is shaped to conform to the cornea of the eye and the front surface of the lens is shaped to provide—in conjunction with the rear surface—the desired optical properties of the central and peripheral optical zones.

Abstract: The present invention relates to aqueous processes for the production of silicone hydrogel contact lenses.

Abstract: A method for making a hydrogel, photochromic contact lens including supplying a first lens composition comprising a contact lens monomer and a photochromic material to a front contact lens mold and supplying a second lens composition to said contact lens mold wherein the viscosity of said first composition is at least about 1000 cp greater than the viscosity of said second contact lens composition, and the makeup of said second composition matches the of said first composition to reduce strain between said compositions of the resulting lens.

Abstract: A contact lens such as a toric contact lens having hybrid stabilization features is disclosed. The lens includes a lens edge, a vertical meridian, a horizontal meridian, a superior region, an inferior region, an optical zone, a prism ballast zone and a peri ballast zone, wherein the contact lens has a dimple zone disposed between the optical zone and the lens edge and is centered on the inferior vertical meridian.

Abstract: A lens is provided that is capable of preventing or slowing the progression of myopia when worn by a person. The lens has a power profile that reduces on-axis and off-axis hyperopic defocus created by the optics of the eye by creating on-axis and off-axis myopic defocus. The on-axis and off-axis myopic defocus is created by providing light rays that pass through a central vision region of the optical portion and light rays that pass through a peripheral region of the optical portion an increase in positive (plus) power. The overall effect is to prevent or slow the progression of myopia without any perceptible degradation in the person's central vision.

Abstract: The invention relates to a photochromic optical article with reduced thermal dependency, comprising: (a) a transparent substrate, (b) a saturated photochromic layer having, in the activated state and at a temperature of 20° C. or greater, a relative transmission factor of less than 1% in the visible range, and (c) an anti-UV coating of plastic material at least partially covering the saturated photochromic layer, the said anti-UV coating containing at least one agent which absorbs UV radiation (anti-UV agent) and is distributed in a pattern consisting of a multitude of points, each having a surface area of less than 0.15 mm 2, the average distance between two neighboring points lying between 0.5 and 2 mm and the ratio of the overall surface area of all the points to the total surface area of the anti-UV coating being such that the relative transmission factor of the optical article in the visible range in the activated state and at 20° C. or greater is at least equal to 5%.

Abstract: A contact lens having a thin silicon chip integrated therein is provided along with methods for assembling the silicon chip within the contact lens. In an aspect, a method includes creating a plurality of lens contact pads on a lens substrate and creating a plurality of chip contact pads on a chip. The method further involves applying assembly bonding material to the each of the plurality of lens contact pads or chip contact pads, aligning the plurality of lens contact pads with the plurality of chip contact pads, bonding the chip to the lens substrate via the assembly bonding material using flip chip bonding, and forming a contact lens with the lens substrate.

Abstract: An optical material is described. The optical material includes at least one layer of a metamaterial. Each layer of metamaterial includes a matrix material and a plurality of nano-particles. The plurality of nano-particles are geometrically arranged in an array within the matrix material such that the layer of metamaterial has a high positive refractive index based on a cooperative plasmon effect at a predetermined electro-magnetic radiation (EMR) wavelength relative to the refractive index of the matrix material without the nano-particles.

Abstract: A contact lens (10) for use in controlling or retarding the progression of myopia in an eye has a central optical zone (20) approximating the normal diameter of the pupil of the eye (22) that gives clear central vision at distance for the wearer. An annular peripheral optical zone 24 that is substantially outside the diameter of the pupil is formed around the central optical zone (20) with greater refractive power than that of the central zone (22) so that oblique rays entering the eye through the peripheral optical zone (24) will be brought to focus at a focal plane that is substantially on or anterior to the peripheral region of the retina. Preferably, the rear surface (16) of the lens is shaped to conform to the cornea of the eye and the front surface (18) of the lens (10) is shaped to provide—in conjunction with the rear surface (16)—the desired optical properties of the central and peripheral optical zones.

Abstract: A method for optimizing the performance in centration, rotation and stability of contact lenses makes use of the upper and lower eyelid geometries to maximize the lens-lid interaction for two different contact lens positions on the eye. The contact lenses are non-round lenses for maximum interaction with the eyelids.

Abstract: A contact lens incorporating one or more compliant dynamic translation zones fabricated from a material that is readily deformable under eyelid pressure during blinking and which allows for the control over translation of the contact lens on the eye. The one or more compliant dynamic translation zones provide for the comfortable relative movement of the contact lens over the eye.

Abstract: The present invention provides a hybrid soft contact lens including a central portion formed with a first hydrous soft material, and a peripheral portion formed with a second hydrous soft material, in which the first hydrous soft material is obtained by curing a first curable composition including a silicone-containing monomer. Preferably, the first hydrous soft material has a Young's modulus of no less than 3.0 MPa and no greater than 100 MPa, and the second hydrous soft material has a Young's modulus of no less than 0.20 MPa and less than 3.0 MPa.

Abstract: An ophthalmic lens incorporating a usage compliance indicator may be utilized to indicate when the lens should be discarded or otherwise treated. The usage compliance indicator comprises a material that is clear when the lens is removed from its packaging and transforms to a visible marking over a given period of time corresponding to the manufacturer's suggested usable time. The material is compatible with the lens material and does not interfere with the optics.

Abstract: This invention discloses apparatus for generating an ophthalmic lens with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture.

Abstract: A lens body comprising at least one form of boronic acid, boronic ester or boronic anhydride is provided. The lens body is contacted with a solution comprising at least one form of TRIS. A contact lens package including the contact lens, and methods of producing and using the contact lens, are also provided.

Abstract: Ophthalmic devices, such as contact lenses, may incorporate myopia control optics in combination with therapeutic agents also known to control myopia to create a drug delivery mechanism to inhibit or arrest the progression of myopia in individuals.

Abstract: An ophthalmic lens incorporating clearly identifiable, highly visible inversion marking(s) that become invisible when placed on the eye may be utilized to allow an individual to easily distinguish between the normal state of the lens and the inverted state of the lens. The ophthalmic lens comprises a thin material layer capable of changing its optical state from diffusive light scattering, colored, or both, to invisible transparent at the corneal temperature of a normal person, at the influence of ambient light, or a combination thereof.

Abstract: A contact lens having one or more fiducial marks that allow the measurement of lens rotation and centration. The lens may be a trial lens. The lenses can be used to apply correction factors for sphero-cylindrical refractive error, higher order aberrations, and corneal topography.

Abstract: Ophthalmically compatible contact lenses include lens bodies configured for placement on a cornea of an animal or human eye. The lens bodies are made of a hydrophilic silicon-containing polymeric material. The lens bodies have oxygen permeabilities, water content, surface wettabilities, flexibilities, and/or designs to be worn by a lens wearer even during sleep. The present lenses can be worn on a daily basis, including overnight, or can be worn for several days, such as about thirty days, without requiring removal or cleaning.

Abstract: A soft contact lens for treating ametropia having an optical zone, a pressure control zone, an alignment zone, and a peripheral zone.

Abstract: Apparatus and methods to increase the depth of field in human vision in order to correct for loss in refocusing ability. Optics variations, such as changes in thickness, shape, or index of refraction of contact lenses, intraocular implants, or the shape of the cornea or eye lens, affect the phase, or wavefront, of the light perceived by the eye. The optics variations are chosen such that the resulting optical transfer function remains relatively constant over a desired range of object distances and pupil diameters.

Abstract: One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising: H3C—(CH2)n—CHmCHmR, where is a single or double carbon-carbon bond, m is 1 or 2, n is 2 to 15, and R is a carboxylic acid, a salt, an ester, or an amide, where the ester or amide is an isostere or biostere of the carboxylic acid. The composition additionally contains an additive component selected from one or more of the group consisting of biocides, surfactants, antibiotics, antiseptics, detergents, chelating agents, virulence factor inhibitors, gels, polymers, pastes, edible products, and chewable products. The composition is formulated so that when it is contacted with a biofilm produced by a microorganism, where the biofilm comprises a matrix and microorganism on a surface, the dispersion inducer selectively acts on the microorganism and has a suitable biological response without a required direct effect on the matrix to disperse the biofilm.

Abstract: Solar cells attached to a contact lens are provided, as well as methods for making the solar cells and contact lenses. The solar cells have electrodes on only one side of the device, which facilitates attachment of the solar cell to a contact lens. In one embodiment, the solar cells are made using a “two sided” process. By using the two-sided process, solar cells of only a few microns in thickness can be fabricated. Such relatively thin solar cells can be incorporated into a contact lens without discomfort to the wearer. By providing an infinitely renewable power source on a contact lens, the solar cells enable the use of electronic components on the contact lens while eliminating the recharging or replacing issues that arise with batteries.

Abstract: Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed.

Abstract: Certain embodiments are directed to lenses, devices and/or methods. For example, a lens for an eye having an optical axis and an aberration profile along its optical axis, the aberration profile having a focal distance and including higher order aberrations having at least one of a primary spherical aberration component C(4,0) and a secondary spherical aberration component C(6,0). The aberration profile may provide, for a model eye with no aberrations and an on-axis length equal to the focal distance: (i) a peak, first retinal image quality (RIQ) within a through focus range that remains at or above a second RIQ over the through focus range that includes said focal distance, where the first RIQ is at least 0.35, the second RIQ is at least 0.1 and the through focus range is at least 1.8 Diopters; (ii) a RIQ of 0.3 with a through focus slope that improves in a direction of eye growth; and (iii) a RIQ of 0.3 with a through focus slope that degrades in a direction of eye growth.

Abstract: Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed.

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract: A contact lens incorporating one or more dynamic fluid zones fabricated from a material that is readily deformable under eyelid pressure during blinking allows for the delivery of one or more agents to the eye, dynamic cosmetic eye enhancement, and/or dynamic rotational misalignment correction. The one or more agents may include therapeutic agents, nutritional agents and pharmacological agents.

Abstract: This invention discloses methods and apparatus for providing a biomedical device, such as an ophthalmic lens with an energy receptor capable of powering a processing device.

Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.

Abstract: A contact lens having nanoparticles integrated within, or deposited onto, the contact lens. A method for altering the optical density and spectral transmission or reflection response of a contact lens. The method includes obtaining a nanoparticle solution having a predetermined concentration. The method further includes exposing the contact lens in the nanoparticle solution for a predetermined period of time. A method for manufacturing a contact lens further includes exposing contact lens material to nanoparticles for a predetermined period of time to alter the optical density and spectral transmission or reflection response of the contact lens material. A contact lens may be formed after the material is exposed to the nanoparticles.

Abstract: A contact lens comprising first and second orientation indicia to determine an orientation of the contact lens.

Abstract: Silicone hydrogel contact lenses are produced without using volatile organic solvents to extract materials from the polymerized contact lens bodies, and instead are washed with aqueous liquids. The silicone hydrogel contact lenses so produced have ophthalmically wettable lens surfaces. The hydrated silicone hydrogel contact lenses have diameters that are at least 24% larger than the diameters of the silicone hydrogel contact lenses prior to hydration or washing.

Abstract: Disclosed herein are synthetic silica-based ocular devices fabricated from a composite material comprising silica and a fibrillar protein, together with methods of making and using the ocular devices.

Abstract: The present invention is directed to a composite lens, comprising an anterior rigid gas permeable layer, and an annulus of soft material bonded to a posterior surface of the anterior rigid gas permeable layer, wherein a central zone of the composite lens is rigid and without a soft layer, wherein a peripheral zone of the composite lens is generally rigid in its anterior aspect and soft in its posterior aspect.

Abstract: Methods, devices, and systems for manufacturing ophthalmic lenses using direct injection molding are described. The present methods, devices, and systems include a mold block having a first mold insert and a second mold insert defining a lens-shaped cavity between them. A raised non-uniform region that projects into the lens-shaped cavity is incorporated in a peripheral zone of the molding surface of at least one of the mold inserts. When an ophthalmic lens is formed using the described mold block, at least one depression is produced in the lens. A gate placed at the non-uniform region allows the depression to hide any gate witness that may form when the mold is closed or separated.

Abstract: Feature patterns may be incorporated into the peripheral region of the back curve surface of contact lenses in order to increase tear exchange between the contact lens and the cornea. The feature patterns may be based upon fractal geometry and be incorporated anywhere in the periphery of the lens. The placement feature patterns are preferably determined utilizing a combination of simulations and experimentation.