Candy, Candy Coated Or Chewing Gum Patents (Class 424/440)
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Patent number: 5004595Abstract: A free-flowing particulate delivery system for providing enhanced flavor and sweetness to comestible compositions comprising a powdered flavor composition encapsulated in a matrix comprising an outer hydrophilic coating containing up to the solubility limit of the coating of an intense sweetener. The delivery system is particularly useful in chewing gums, confectioneries and pharmaceutical preparations as well as other food products.Type: GrantFiled: March 30, 1990Date of Patent: April 2, 1991Assignee: Warner-Lambert CompanyInventors: Subraman R. Cherukuri, Tommy L. Chau, Krishna P. Raman, Angel M. Orama
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Patent number: 5002759Abstract: A method of, and oral composition for, inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these cells with an oligosaccharide having at least one fucose moiety or a galactose moiety which is free of digalactose and N-acetylneuraminyl lactose.Type: GrantFiled: July 25, 1989Date of Patent: March 26, 1991Assignees: Colgate-Palmolive Company, Forsyth Dental CenterInventors: Abdul Gaffar, Ronald J. Gibbons, Stanislawa Tylewksa
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Patent number: 5002970Abstract: An oral composition containing ionizable compounds of zinc flavor-masked with anethole and prepared in the forms of pleasant tasting lozenges, soft candies, syrups, powders and chewing gums for delivery of zinc to the oral and oral pharyngeal mucosa of a human with said composition being absent the taste or aftertaste of zinc, and being primarily intended for use in treating the common cold.Type: GrantFiled: April 18, 1988Date of Patent: March 26, 1991Inventor: George A. Eby, III
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Patent number: 4999185Abstract: A composition for inhibiting sordes formation is adapted for application to the oral cavity and contains an amount of isolated cacao husk extract effective to inhibit sordes formation. The cacao husk extract is extracted from cacao husks with a polar solvent. It has been found that the composition according to the invention inhibits glucosyltransferase activity, and thereby inhibits glucan synthesis. The composition may take the form of chocolates, stick gum, candy, biscuits, chocolate milk or ice cream incorporating the extract, or the extract may also be formulated as a tablet, toothpaste or mouthwash.Type: GrantFiled: May 30, 1989Date of Patent: March 12, 1991Assignee: Lotte Company LimitedInventors: Toshio Takemori, Tsutomu Arakawa, Teruo Matsumoto, Takashi Maruyama
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Patent number: 4997654Abstract: A method for treating xerostomia which comprises chewing gum or candy containing from 4 to 70 weight percent xylitol therein.Type: GrantFiled: August 14, 1989Date of Patent: March 5, 1991Assignee: Warner-Lambert CompanyInventors: Vincent Corsello, Michael Glass, Norton Ross, Joseph Hohclick, Kenneth P. Bilka
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Patent number: 4997856Abstract: Floss spun from a mixture of a saccharide and an oleaginous substance which includes a medicament distributed on or through the fibers is compacted and chopped by passing through a conventional "food grinder" or equivalent having an auger feed to a cutter and orifice plate outlet. The enclosed volume of the end product is less than 30% and preferably less than 15% of the as-spun volume of the floss. This volume reduction is accomplished without distroying the colloidal-like behavior of the product. The compressed particles are readily metered for producing dosage units within required tolerances.Type: GrantFiled: November 30, 1989Date of Patent: March 5, 1991Assignee: Fuisz Pharmaceutical Ltd.Inventor: Richard C. Fuisz
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Patent number: 4994276Abstract: A free-flowing directly compressible granulation useful as a slow release pharmaceutical excipient is disclosed. The excipient includes a hydrodrophilic matrix which includes a heteropolysaccharide and a polysaccharide material capable of cross-linking the heteropolysaccharide, and an inert diluent.Type: GrantFiled: September 19, 1988Date of Patent: February 19, 1991Assignee: Edward Mendell Co., Inc.Inventors: Anand R. Baichwal, John N. Staniforth
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Patent number: 4992256Abstract: Dental plaque-disclosing compositions comprising FD&C Red No. 40 which selectively stain plaque formed on tooth surfaces, making plaque easily observable to the naked eye at visible light wave-lengths.Type: GrantFiled: September 27, 1989Date of Patent: February 12, 1991Assignee: Colgate-Palmolive CompanyInventors: J. Michael Skaggs, Robert E. Dickson, James H. Bowers, Edward A. Tavss
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Patent number: 4988683Abstract: This invention relates to the field of pharmaceutical chemistry and more precisely to the field of galenical pharmacy.It refers to new pharmaceutical compositions intended for the buccal tract, the active ingredient of which is lysine acetylsalicylate in association or mixed with one or several excipients and/or diluents adapted to achieve a pharmaceutical form which may be sucked or chewed. A process for the production of said pharmaceutical composition is also described.Type: GrantFiled: July 20, 1989Date of Patent: January 29, 1991Inventor: Jerome Corbiere
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Patent number: 4985252Abstract: A powdered composition obtained by adsorption of active ingedients, previously dissolved in an organic solvent, on instant sugar, and a process for producing this composition. As a medication, it contains at least one medically active ingredient adsorbed on the external and/or internal surface of particles of an instant sugar very rapidly soluble in water.Type: GrantFiled: April 4, 1988Date of Patent: January 15, 1991Assignee: R. I. Ph. Recherche Informatique et Pharmacie (S.A.R.L.)Inventors: Christophe Jung, Jean Jung
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Patent number: 4983378Abstract: Methods and compositions are provided for alleviating xerostomia. The compositions are formulated from Yerba Santa extract and sweetener, and may be in aqueous solution or in gum or lozenge form. The compositions may additionally contain a stimulator compound effective to stimulate salivary gland secretion, e.g., citric acid, ascorbic acid, or both. Preservatives, flavoring agents, coloring agents, emulsifiers, and the like may be included in the compositions as well. The Yerba Santa-based compositions of the invention are orally administered to an affected patient to alleviate the symptoms of dry mouth.Type: GrantFiled: March 12, 1990Date of Patent: January 8, 1991Assignee: Parnell Pharmaceuticals, Inc.Inventor: Francis W. Parnell
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Patent number: 4983394Abstract: Confections containing a volatile oil and designed for dissolving in the oral cavity containing novel volatile oil masking agents are disclosed. The volatile oil masking agents significantly suppress the perception of unpleasant organoleptic sensations such as bitterness or medicinal off-taste initiated by the volatile oil being released in the oral cavity. Masking agents such as fenchone and d-borneol are present in the confection in sensorially undetectable amounts to provide masking of unpleasant characteristics of volatile oils without detracting from the desired organoleptic sensations of taste and the preception of vapor action in the oral cavity.Type: GrantFiled: May 3, 1990Date of Patent: January 8, 1991Assignee: Warner-Lambert CompanyInventors: Mamoun M. Hussein, Shirley A. Barcelon
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Patent number: 4980169Abstract: A novel confection containing a volatile oil for dissolving in the oral cavity is disclosed. The confection contains a sensorially undetectable amount of a volatile oil modifying agent which enhances the flavor of the volatile oil as well as ameliorates the perception of unpleasant organoleptic sensations such as bitterness initiated by the volatile oil being released in the oral cavity. In a preferred embodiment, the modifying agent is capsicum and most preferably, the oleoresin form of capsicum.Type: GrantFiled: May 3, 1990Date of Patent: December 25, 1990Assignee: Warner-Lambert CompanyInventors: Alfred Oppenheimer, Ralph Cifrese, Mamoun M. Hussein, Vincent Corsello
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Patent number: 4975270Abstract: Active ingredients useful in chewable articles of commerce are physically encased in non-porous, chewable, particles of elastomer and such particles are then incorporated in the articles of commerce. During mastication of the chewable article of commerce the active ingredient is released from the elastomer particles over a prolonged period of time. The active ingredients would include flavorants, intense sweeteners, colorants, medicaments, effervescent agents and tobacco.Type: GrantFiled: April 21, 1987Date of Patent: December 4, 1990Assignee: Nabisco Brands, Inc.Inventor: Gary S. Kehoe
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Patent number: 4971797Abstract: The chlorosucrose sweetener known as sucralose is prepared in a thermally stable composition by co-crystallization with a cyclodextrin. The resulting crystalline product may be comminuted to form particles of desired size for use as a sweetener component in place of or in addition to known sweeteners such as sucrose, saccharin and the like, in a variety of foods, comestibles, and oral medications. The preparation of the stabilized sucralose compositions of the present invention constitutes a molecular encapsulation of the sucralose within the cyclodextrin thereby protecting the sucralose from discoloration caused by heat. Numerous applications for this stabilized complex are suggested and disclosed.Type: GrantFiled: December 22, 1988Date of Patent: November 20, 1990Assignee: Warner-Lambert CompanyInventors: Subraman R. Cherukuri, Lucy L. Wong
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Patent number: 4971798Abstract: Disclosed is a hard confection containing Palatinit (hydrogenated isomaltulose) and a medicinally active ingredient. Such a formulation has been found to dissolve more slowly than similar formulations based on sugar rendering them suitable for dispensing the active ingredient over an extended period of time.Type: GrantFiled: November 30, 1989Date of Patent: November 20, 1990Assignee: Miles Inc.Inventors: Kenneth A. Coia, Michael J. Lynch
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Patent number: 4970236Abstract: A month-soluble pharmaceutical composition comprising acetylcysteine, alkaline, bicarbonates, carbohydrates and fruit flavoring, produced in the form of tablets for treating affections of the oral cavity.Type: GrantFiled: April 26, 1989Date of Patent: November 13, 1990Assignee: Altergon S.A.Inventors: Antonio Ziggiotti, Paolo Lualdi
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Patent number: 4968694Abstract: A fiber-containing product based on seeds of leguminous plants comprises the cell wall ingredients of the seed, said ingredients being isolated upon previous removal of the seed coat. The product is prepared by whole seeds of leguminous plants being shelled to remove the cellulose-containing seed coat and being rinsed and steamed for bacteriological reasons are wet-ground to open the plant cells and to dissolve or suspend the starch particles, proteins, and soluble components contained in the plant cells; whereafter proteins, salts, soluble ingredients, and starch particles are removed as a filtrate through a filtration on a centrifugal sieve followed by a washing, filtration, and pressing of the resulting filter cake to increase the dry matter content before the filter cake is rasped and dried. The fiber product can be used when preparing e.g.Type: GrantFiled: June 22, 1987Date of Patent: November 6, 1990Assignee: Danisco A/SInventors: Rud F. Madsen, Kirsten Buchbjerg, Ole R. Jensen
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Patent number: 4963359Abstract: A non-cariogenic confectionery base free of cellulosics and graining compounds containing hydrogenated starch hydrolysates e.g. Lycasin 85%, more than 10 to about 50% by weight of at least one edible oil, fat, wax or mixtures thereof and an emulsifying amount of at least one emulsifier and a method of making same are disclosed. A non-cariogenic confectionery composition containing said confectionery base in homogeneous admixture with a semi-solid matrix containing various ingredients and optionally at least one medicament is also disclosed.Type: GrantFiled: January 30, 1989Date of Patent: October 16, 1990Assignee: Plough, Inc.Inventors: Joseph Haslwanter, Walter G. Chambliss
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Patent number: 4956385Abstract: This invention discloses and claims improved methods to reduce duration of common colds in humans through use of pharmaceutically acceptable zinc compounds topically and frequently applied to the oral mucosa by various means. The invention improves upon the prior art using zinc gluconate throat lozenges to reduce the duration of common colds and zinc borate intranasally as an astringent and decongestant in treatment of common colds.Type: GrantFiled: September 24, 1987Date of Patent: September 11, 1990Inventor: George A. Eby, III
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Patent number: 4952407Abstract: A gum composition useful in dental plaque removal and suppression and method of use is disclosed. The composition comprises 15 to 90% gum base, 5 to 80% sweetening and bulking agents, 1 to 10% glycerine, optional color and flavor, and contains 0.25 to 0.75% glycerol mono laurate. Preferably, the composition also includes a high filler content. The method involves chewing the gum composition the invention for at least 20 minutes, preferably at least five times a day for four successive days.Type: GrantFiled: September 12, 1988Date of Patent: August 28, 1990Assignee: Wm. Wrigley Jr. CompanyInventors: David W. Record, Mansukh M. Patel
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Patent number: 4952402Abstract: A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingedient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37.degree. C. and 75 r.p.m.Type: GrantFiled: March 17, 1988Date of Patent: August 28, 1990Assignee: Elan Corporation, p.l.c.Inventors: Randall T. Sparks, Edward J. Geoghegan
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Patent number: 4940588Abstract: A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingredient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37.degree. C. and 75 r.p.m.Type: GrantFiled: March 17, 1988Date of Patent: July 10, 1990Assignee: Elan CorporationInventors: Randall T. Sparks, Edward J. Geoghegan
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Patent number: 4938963Abstract: Methods and compositions are provided for alleviating xerostomia. The compositions are formulated from Yerba Santa extract and sweetener, and may be in aqueous solution or in gum or lozenge form. The compositions may additionally contain a stimulator compound effective to stimulate salivary gland secretion, e.g., citric acid, ascorbic acid, or both. Preservatives, flavoring agents, coloring agents, emulsifiers, and the like may be included in the compositions as well. The Yerba Santa-based compositions of the invention are orally administered to an affected patient to alleviate the symptoms of dry mouth.Type: GrantFiled: November 22, 1988Date of Patent: July 3, 1990Assignee: Parnell Pharmaceuticals, Inc.Inventor: Francis W. Parnell
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Patent number: 4935242Abstract: A drug delivery system comprising a core material comprising a drug, and a hydrophobic matrix coating the core. The coating delays hydration of the drug and masks the taste of the drug. The coating comprises an emulsifier, an edible fatty acid or wax and a glyceride. The delivery system can be incorporated into various food products, pharmaceutical preparations and proprietary products.Type: GrantFiled: July 26, 1988Date of Patent: June 19, 1990Assignee: Warner-Lambert CompanyInventors: Shri C. Sharma, James J. Shaw, Robert K. Yang
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Patent number: 4933183Abstract: A drug delivery system comprising a core material comprising a drug, and a hydrophobic matrix coating the core. The coating delays hydration of the drug and masks the taste of the drug. The coating comprises an emulsifier, an edible fatty acid or wax and a glyceride. The delivery system can be incorporated into various food products, pharmaceutical preparations and proprietary products.Type: GrantFiled: July 26, 1988Date of Patent: June 12, 1990Assignee: Warner-Lambert CompanyInventors: Shri C. Sharma, James J. Shaw, Robert K. Yang
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Patent number: 4931280Abstract: The edible baked composition delivers cholestyramine in a palatable, pleasant tasting form. Embodiments include a nutrition bar and a cookie. The composition is useful for the control of endogenous cholesterol levels in humans.Type: GrantFiled: June 13, 1988Date of Patent: June 5, 1990Assignee: BASF K & F CorporationInventors: Thomas G. Wood, Carol J. Xenides
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Patent number: 4929508Abstract: A drug delivery system comprising a core material comprising a drug, and a hydrophobic matrix coating the core. The coating delays hydration of the drug and masks the taste of the drug. The coating comprises an emulsifier, an edible fatty acid or wax and a glyceride. The delivery system can be incorporated into various food products, pharmaceutical preparations and proprietary products.Type: GrantFiled: July 26, 1988Date of Patent: May 29, 1990Assignee: Warner-Lambert CompanyInventors: Shri C. Sharma, James J. Shaw, Robert K. Yang
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Patent number: 4929447Abstract: The present invention is method and composition for protecting an active ingredient and providing controlled release therefor, especially in a chewing gum composition, which includes a high molecular weight polyvinyl acetate blended with a hydrophobic plasticizer which forms a film with the high molecular weight polyvinyl acetate in the absence of an added solvent therefor. The active ingredient, such as the artificial sweetener aspartame, is blended into the encapsulating composition as, for example, by melt blend which can then be cooled to a solid and ground into particulate. The encapsulated active ingredient can then be used in a composition for ingestion by a human in the form of, for example, a chewing gum with extended shelf life and highly controlled release of the active ingredient.Type: GrantFiled: June 29, 1987Date of Patent: May 29, 1990Assignee: Warner-Lambert CompanyInventor: Robert K. Yang
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Patent number: 4927634Abstract: Novel pharmaceutical compositions of matter are disclosed for use in eliciting a topical anesthetic and antimicrobial response, preferably for oral health care purposes, said compositions comprising dyclonine hydrochloride and phenol. When used in combination, dyclonine hydrochloride and phenol provide an improved antimicrobial response.Type: GrantFiled: January 13, 1989Date of Patent: May 22, 1990Assignee: Richardson-Vicks Inc.Inventors: James V. Sorrentino, William J. Kelleher, Jeanne O. Moye
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Patent number: 4925669Abstract: A therapeutic composition for veterinary use comprises a therapeutic agent associated by sorption and/or adsorption with a substrate selected from zeolites and pillared clays.Type: GrantFiled: November 16, 1987Date of Patent: May 15, 1990Inventors: Alan Dyer, Phyllis D. Wells, Craig D. Williams
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Patent number: 4917894Abstract: An oral anesthetic composition comprising an anesthetically effective amount of a compound of formula (I) ##STR1## wherein R is alkyl of 2 to 8 carbon atoms or a pharmaceutically acceptable salt thereof and an anesthetically effective amount of a rapid-onset anesthetic selected from the group consisting of benzyl alcohol, phenol, phenolate sodium, hexylresorcinol, menthol, salicyl alcohol and benzocaine in combination with a pharmaceutically acceptable carrier, said carrier being in orally administrable form.Type: GrantFiled: June 29, 1988Date of Patent: April 17, 1990Assignee: Beecham Inc.Inventors: Joseph A. Matthias, Kim L. Bildstein
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Patent number: 4908212Abstract: Chewing gum designed to prevent tooth decay, for which a cacao bean husk is extracted by adding water or ethyl alcohol and an extract which is freeze dried after solvent is collected and concentrated by vacuum evaporation is added to the known raw materials of chewing gum in the ratio of 0.1-1.0%.Type: GrantFiled: January 13, 1989Date of Patent: March 13, 1990Assignee: Lotte Confectionery Co., Ltd.Inventors: Ik B. Kwon, Hyung H. Park, Bong J. An
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Patent number: 4908211Abstract: Chewing gum or a chewable confection including either sanguinarine, benzophenanthridine alkaloid, or soluble poly-pyrophosphates, or both to chemically inhibit the formation of plaque and calculus.Type: GrantFiled: June 9, 1988Date of Patent: March 13, 1990Inventor: Armando F. Paz
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Patent number: 4906480Abstract: A low concentration of polyphenols, particularly flavonoid compounds, such as flavonols, and more particularly catechin compounds, employed as additives to compositions containing sweeteners and/or flavoring agents, or both, significantly enhanced the sweetness and flavor and especially, extended the sweetness and flavor time. A composition, such as chewing gum, which comprises a sweetening or flavoring agent, or both, and a sweetness or flavor extending or enhancing amount of a flavonoid compound, such as a catechin compound. A method of extending and enhancing the flavor and sweetness of a composition, such as chewing gum, food or beverage, which method comprises incorporating onto or into the composition a flavor or sweetness extending or enhancing amount of a flavonoid compound, such as a catechin compound.Type: GrantFiled: April 7, 1988Date of Patent: March 6, 1990Assignee: Forsyth Dental Infirmary for ChildrenInventor: Shelby Kashket
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Patent number: 4894234Abstract: A drug delivery system comprising a core material comprising a drug, and a hydrophobic matrix coating the core. The coating delays hydration of the drug and masks the taste of the drug. The coating comprises an emulsifier, an edible fatty acid or wax and a glyceride. The delivery system can be incorporated into various food products, pharmaceutical preparations and proprietary products.Type: GrantFiled: July 26, 1988Date of Patent: January 16, 1990Inventors: Shri C. Sharma, James J. Shaw, Robert K. Yang
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Patent number: 4894233Abstract: A drug delivery system comprising a core material comprising a drug, and a hydrophobic matrix coating the core. The coating delays hydration of the drug and masks the taste of the drug. The coating comprises an emulsifier, an edible fatty acid or wax and a glyceride. The delivery system can be incorporated into various food products, pharmaceutical preparations and proprietary products.Type: GrantFiled: July 26, 1988Date of Patent: January 16, 1990Inventors: Shri C. Sharma, James J. Shaw, Robert K. Yang
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Patent number: 4891210Abstract: Acid forming bacteria in the mouth are controlled by the use of bacteriophages so reducing acid which can cause dental caries.Type: GrantFiled: January 3, 1989Date of Patent: January 2, 1990Inventor: Alan H. Norris
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Patent number: 4885173Type: GrantFiled: June 8, 1987Date of Patent: December 5, 1989Assignee: University of UtahInventors: Theodore H. Stanley, Brian Hague
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Patent number: 4882157Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882158Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882152Abstract: A chewable delivery system for actives comprising:(a) an active pre-coatd with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and p1 (b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882159Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkylenglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882154Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons of less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 13, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882160Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 13, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882151Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lenghts of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant maerial selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882155Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882156Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882153Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 13, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: RE33465Abstract: The invention disclosed and claimed is a method to reduce duration of common colds in humans as evinced by reduction of duration of 10 common cold symptoms through use of zinc gluconate topically and frequently applied to the oral mucosa. The invention improves upon the prior art using zinc intranasally as an astringent and decongestant in treatment of common colds. Results of a clinical study are presented in support of disclosure and claims.Type: GrantFiled: April 4, 1986Date of Patent: November 27, 1990Inventor: George A. Eby, III