Candy, Candy Coated Or Chewing Gum Patents (Class 424/440)
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Patent number: 5215750Abstract: Compositions comprising L-glutamine in combination with vitamins, minerals, choline, and flavonoids are disclosed. Such compositions can be administered to effect weight reduction, or to aid in weight control.Type: GrantFiled: September 4, 1991Date of Patent: June 1, 1993Inventor: Michael A. Keane, II
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Patent number: 5213615Abstract: A dental material for the control of caries and paradentitis is described, which contains an active agent combination of thymol and/or carvacrol and chlorhexidine and/or the physiologically compatible salts thereof.The dental material can be a dental varnish or a material such as a dental cement and the like, which remains in the oral cavity for a long period and from which the active combination can diffuse out.Type: GrantFiled: March 1, 1989Date of Patent: May 25, 1993Assignee: Ivoclar AGInventor: Rudolf J. Michl
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Patent number: 5213803Abstract: A method utilizing compositions for topical application which are adapted for the prevention and treatment of viral infections such as Herpes, AIDS and other envelope virus infections are disclosed. The compositions of the present invention produce a synergistic anti-viral effect when used in combination. The formulation contains a humectant such as sorbitol, glycerol, or other comparable compound in the range of 20-80% w/v final concentration, which facilitates structural and/or functional three dimensional disruption or disorientation of the viral envelope. The activation of the destruction of the envelope and subsequent death of the envelope virus is then achieved using combination of inorganic monovalent anions, nonionic detergents and anionic detergents. These monovalent anions can include sodium bicarbonate, sodium thiocyanate, sodium fluoride and sodium chloride at about 0.5 to 5% w/v final concentration; nonionic detergents such as Tween 20 at concentrations of about 0.Type: GrantFiled: February 24, 1992Date of Patent: May 25, 1993Assignee: Northeastern Ohio Universities College of MedicineInventors: Jerry J. Pollock, John J. Docherty
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Patent number: 5208039Abstract: Synthetic or semisynthetic nutrient composition intended to inhibit the development and the dissemination of malignant tumors in mammals, which composition is characterized in that it is deprived of methionine and supplemented with homocysteine; and utilization, in the preparation of such nutrient compositions, of a source of amino acids deprived of methionine.Type: GrantFiled: December 26, 1989Date of Patent: May 4, 1993Assignee: Centre National de la Recherche Scientifique (CNRS)Inventors: Marie-France Poupon, Paule Echinard-Garin, Fabienne R. Breillout
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Patent number: 5206025Abstract: New porous, unitary freeze-dried pharmaceutical form, of homogeneous appearance, consisting of:a) an inclusion compound comprising:one or optionally more active substances,a predetermined quantity of cyclodextrin,optionally an additive facilitating inclusion,b) at least one substance chosen from:diluents,binders; andc) optionally one or more additives.Type: GrantFiled: June 4, 1992Date of Patent: April 27, 1993Assignee: Rhone-Poulenc SanteInventors: Frederic Courteille, Magali Vanhoeve
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Patent number: 5204115Abstract: A directly compressible xylitol granulate comprising xylitol and a physiologically acceptable, non-cariogenic binder taken from the group consisting of polymerized reducing sugars, an alkali carboxymethylcellulose and hydrogenated starch hydrolysate. The granulate is directly compressible and exhibits the taste profile, metabolic and cariostatic properties of xylitol.Type: GrantFiled: December 12, 1990Date of Patent: April 20, 1993Assignee: Suomen Xyrofin OyInventors: Philip M. Olinger, Auli Karhunen
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Patent number: 5188825Abstract: A method of preparing a freeze-dried dosage form including a water soluble active agent is disclosed. The water soluble active agent is bonded to an ion exchange resin to form a substantially water insoluble complex. This complex is then mixed with a compatible carrier and freeze-dried. The resulting freeze-dried dosage form contains an effective unit dosage amount of the active agent and exhibits enhanced compositional and physical stability, as well as permitting processing according to conventional freeze-drying techniques.Type: GrantFiled: December 28, 1989Date of Patent: February 23, 1993Inventors: Martin C. Iles, Angela D. Atherton, Neil M. Copping
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Patent number: 5188817Abstract: A method of treatment for periodontitis comprises the topical or systemic administration of a pharmaceutical composition containing at least one retinoid compound other than Vitamin A. Preferred retinoids include Vitamin A aldehyde, Vitamin A acid, Vitamin A esters, isotretinoin, etretinate and acitretin.Type: GrantFiled: August 31, 1990Date of Patent: February 23, 1993Inventor: Julius Ozick
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Patent number: 5185153Abstract: The present invention provides compositions for the lysis and killing of microbes in general, and in particular provides oral compositions for the lysis and killing oral bacteria. The compositions of the present invention include a humectant such as glycerol, sorbitol or comparable compounds and provide an in-mouth concentration of such substances from about 20% to about 80% weight/volume in dentifrice preparations, in particular mouthrinses. These compositions further comprises (a) bicarbonate ion at about 0.5% to about 2% wt./vol. and if desired, thiocyanate, chloride or fluoride ion at about 0.5% to about 2% wt./vol. (b) sodium lauroyl sarcosinate or other anionic detergents from about 0.05% to about 1% wt./vol. and (c) Tween 20 or other non-ionic detergents or structurally similar compounds from about 0.01% to about 3% vol./vol. In addition, alcohol may be added up to a level of 15% vol./vol. along with appropriate sweetening and flavoring agents. Water is then added to 100%.Type: GrantFiled: October 4, 1990Date of Patent: February 9, 1993Assignee: The Research Foundation of the State University of New YorkInventor: Jerry J. Pollock
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Patent number: 5182114Abstract: Non-cariogenic sugar composition comprising 2 to 10 ppm fluoride, and preferably 50 to 400 mg/100 g each of calcium ion and phosphate (calculated as P) and 5 to 50 mg/100 g magnesium. The composition is made by blending a composition deficient in fluoride ion with a composition superabundant in fluoride ion, preferably obtained by selection of a superabundant fluoride ion containing fraction of cane sugar containing molasses, such as raw cane sugar, molasses, affination syrup, dried solids of molasses or of affination syrup or a blend thereof with refined sugar, or by evaporation of a mineral water to obtain a concentrate.Type: GrantFiled: November 20, 1990Date of Patent: January 26, 1993Assignee: Jacobs Suchard AGInventors: Eric Blaser, Albert Zumbe
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Patent number: 5182099Abstract: A method of preventing or decreasing the emission of mercury vapor in the mouth, from a mercury amalgam filling, comprising contacting the amalgam filling with an oral composition containing sulfur in an amount sufficient to reduce or eliminate the emission of mercury or mercury vapor. The oral composition may be in the form of a toothpaste, chewing gum, mouthwash water, mouth spray, or the like.Type: GrantFiled: August 27, 1991Date of Patent: January 26, 1993Assignee: Swedima, Inc.Inventors: Eston Jonsson, Roland Waern
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Patent number: 5178850Abstract: A pharmaceutical composition comprising a crystalline sugar alcohol derived from at least one mono- or polysaccharide having at least one liquid pharmaceutically active compound uniformly dispersed within its crystal matrix is disclosed. Also disclosed is a method of producing such a uniformly dispersed pharmaceutical composition by the controlled crystallization of the molten sugar alcohol having the pharmaceutically active material dispersed therein.Type: GrantFiled: June 15, 1990Date of Patent: January 12, 1993Assignee: ICI Americas Inc.Inventor: James W. DuRoss
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Patent number: 5171575Abstract: There is disclosed a pharmaceutical composition for animals comprising at least one of a vinegar, a flesh of Japanese apricot, oranges, tomatoes and strawberries; and saccharides or a combination of saccharides and an edible organic acid, and optionally containing Lactobacillus bifidus.Type: GrantFiled: July 2, 1991Date of Patent: December 15, 1992Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Kenji Shibata, Masami Ozima, Takeaki Hasegawa
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Patent number: 5167964Abstract: The present invention pertains to semi-enteric drug delivery systems which comprise (a) an inert core, (b) a first coating layer over the core comprising a medicament, and (c) a second coating layer over the first coating layer comprising a mixture of methacrylic acid copolymer, type C, and povidone present in a ratio by weight of from about 2:1 to about 24:1, respectively.Type: GrantFiled: February 14, 1992Date of Patent: December 1, 1992Assignee: Warner-Lambert CompanyInventors: Nouman Muhammad, Michael Harris, Jay Weiss, Russell U. Nesbitt
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Patent number: 5166142Abstract: A method is provided to lower serum cholesterol, total triglycerides and/or apoprotein B in a human by administering an effective amount of one or more Type IA antiarrhythmic agents to said human.Type: GrantFiled: June 10, 1991Date of Patent: November 24, 1992Assignee: University of RochesterInventors: Arthur J. Moss, William E. Boden
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Patent number: 5158765Abstract: A depilatory composition for the removal of hair is composed of a mixture of sugar, water and aspirin. This mixture is heated to dissolve the solute materials, and then allowed to cool so as to form a soft, pliable composition which can be manually applied to the skin. The composition firmly adheres to the hair with which it comes in contact, and by quickly drawing the applied material away from the skin, will cause the hair to be removed from its roots without causing undue irritation or swelling.Type: GrantFiled: March 29, 1991Date of Patent: October 27, 1992Assignees: Patricia A. Qasem, Abdullah Mohammad QasemInventor: Patricia A. Qasem
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Patent number: 5156845Abstract: A dry mouth lozenge comprising a base, a pharmaceutically acceptable acedulate, such as a natural sweetener, betaine hydrochloride and a phramaceutically acceptable fluoride.Type: GrantFiled: May 4, 1990Date of Patent: October 20, 1992Assignee: Colgate-Palmolive CompanyInventor: Marcus G. Grodberg
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Patent number: 5154927Abstract: A chewing gum that contains porous polymeric beads impregnated with active gum ingredients together with a method of making such a chewing gum.Type: GrantFiled: June 22, 1990Date of Patent: October 13, 1992Assignee: Wm. Wrigley Jr. CompanyInventors: Joo H. Song, Michael J. Greenberg, David W. Record, Steven E. Zibell, Kevin Broderick, Philip G. Schnell
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Patent number: 5149521Abstract: A composition for use in the oral cavity comprising (A) an easily breakable granule, (B) menthol and/or a natural substance containing menthol, and (C) a flavoring component such as basil, laurel, lavender or a lactone. Although the composition contains an easily breakable granule, which causes a powdery sensation characteristic of compositions containing granules, the present composition exhibits a greatly reduced powdery feeling, and gives a pleasant feeling to users. The composition is particularly suitable as a dentifrice.Type: GrantFiled: August 28, 1991Date of Patent: September 22, 1992Assignee: Kao CorporationInventors: Kazuko Hirose, Kouji Maeda, Kenichi Arai, Takeshi Inoue
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Patent number: 5139787Abstract: A chewing gum that contains water-insoluble porous polymeric beads impregnated with a sweetener, and a method of making such a chewing gum.Type: GrantFiled: December 20, 1990Date of Patent: August 18, 1992Assignee: Wm. Wrigley Jr. CompanyInventors: Kevin B. Broderick, David W. Record
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Patent number: 5135757Abstract: A free-flowing directly compressible granulation useful as a slow release pharmaceutical excipient is disclosed. The excipient includes a hydrodrophilic matrix which includes heteropolysaccharide and a polysaccharide material capable of cross-linking the heteropolysaccharide, and an inert diluent.Type: GrantFiled: January 16, 1991Date of Patent: August 4, 1992Assignee: Edward Mendell Co., Inc.Inventors: Anand R. Baichwal, John N. Staniforth
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Patent number: 5134162Abstract: A process for lowering the blood cholesterol of hyperlipidemic patients by oral ingestion of pyruvate and a confection (cereal bar, fruit bar, candy) containing pyruvate as the ingestion medium.Type: GrantFiled: December 24, 1990Date of Patent: July 28, 1992Assignee: The Montefiore Hospital Association of Western PennsylvaniaInventor: Ronald T. Stanko
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Patent number: 5132114Abstract: Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored confectionary base and to compress or otherwise attach the solid confectionary mixture onto an appliance or holder.Employing the present invention the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a compressed powder "candy" matrix.Type: GrantFiled: September 5, 1989Date of Patent: July 21, 1992Assignee: University of Utah Research FoundationInventors: Theodore H. Stanley, Brian Hague
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Patent number: 5130146Abstract: A colloidal solution comprises a fluoride(s) being difficultly soluble in water comprises colloidal particles of the fluoride having a particle size of 0.005 to 1 micron, said fluoride having a fluoride ion concentration of 1 to 10,000 ppm in the state of saturation.Type: GrantFiled: June 10, 1991Date of Patent: July 14, 1992Assignee: Kao CorporationInventors: Satoshi Tsujita, Manabu Tonomura, Shigeto Kayane, Takashi Imamura
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Patent number: 5128143Abstract: A slow release pharmaceutical excipient of an inert diluent and a hydrodrophilic material including xanthan gum and a galactomannan gum capable of cross-linking the xanthan gum in the presence of aqueous solutions.Type: GrantFiled: March 9, 1990Date of Patent: July 7, 1992Assignee: Edward Mendell Co., Inc.Inventors: Anand R. Baichwal, John N. Staniforth
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Patent number: 5124156Abstract: A chewing gum for preventing pyorrhea alveolaris contains 0.2 to 3.0% of lysozyme of egg white and 0.05 to 0.5% of mace extract.Type: GrantFiled: August 20, 1990Date of Patent: June 23, 1992Assignee: Lotte Company LimitedInventors: Masaki Shibata, Toshio Takiguchi, Yoji Saeki, Hajime Nunome
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Patent number: 5112604Abstract: An aqueous suspension for oral administration of a drug, which suspension is storage stable for a prolonged period and maintains the drug in suspension during such period.Type: GrantFiled: September 1, 1989Date of Patent: May 12, 1992Assignee: Riker Laboratories, Inc.Inventors: Joseph M. Beaurline, Stephen M. Berge, Robert K. Schultz
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Patent number: 5102664Abstract: The application discloses a good-tasting and palatable gritty drug formulation, wherein the grittiness is associated as a part of a pleasurable organoleptic sensation, which contains a gritty and optionally bad-tasting or odoriferous drug and a seedy fibrous fruit, and optionally an aqueous medium and a gelling agent, and preferably also a sweetener and a flavoring agent, wherein the gritty drug is representatively an antihypercholesterolemic drug, especially a bile acid sequestrant, and particularly cholestyramine, a method for the preparation thereof, and a method of converting a gritty drug into a more readily-acceptable formulation which assists with patient compliance.Type: GrantFiled: July 19, 1989Date of Patent: April 7, 1992Inventor: Charles E. Day
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Patent number: 5102666Abstract: Controlled release compositions comprising calcium polycarbophil and an active agent selected from the group consisting of medicinal agents, breath fresheners, and flavors, and a method of controlled release of such an active agent.Type: GrantFiled: September 11, 1990Date of Patent: April 7, 1992Assignee: Oramed, Inc.Inventor: Ramesh N. Acharya
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Patent number: 5095035Abstract: Thermally, chemically and flavor stable compositions for oral absorption by a human containing zinc acetate with a consumable, sweet pharmaceutical carrier and prepared in the form of a pleasant testing lozenge, powder, liquid or chewable composition for delivery of zinc to the oral and oral pharyngeal mucosa of a human with said composition being absent the normal offensive aftertaste of zinc, and being primarily intended for use in treating common colds or in nutritional supplementation.Type: GrantFiled: December 24, 1990Date of Patent: March 10, 1992Inventor: George A. Eby, III
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Patent number: 5085850Abstract: Compositions having improved anti-plaque and anti-gingivitis activity comprise a synergistic combination of a) a morpholinoamino alcohol or salt thereof, such as 3-(4- propylheptyl)-4-(2-hydroxyethyl) morpholine, and b) a metal salt, such as the salts of divalent zinc, copper and magnesium.Type: GrantFiled: November 9, 1990Date of Patent: February 4, 1992Assignee: Warner-Lambert CompanyInventors: Pauline H. Pan, Steven S. Dills, Donald M. Lynch, Lori D. Kumar
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Patent number: 5075291Abstract: A pharmaceutical composition comprising a crystalline sugar alcohol derived from at least one mono- or polysaccharide having uniformly dispersed within its crystal matrix particles of at least one pharmaceutically active compound is disclosed. Also disclosed is a method of producing such a uniformly dispersed pharmaceutical composition by the controlled crystallization of the molten sugar alcohol having the pharmaceutically active material dispersed therein.Type: GrantFiled: November 22, 1989Date of Patent: December 24, 1991Assignee: ICI Americas Inc.Inventor: James W. DuRoss
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Patent number: 5069904Abstract: A method of using nicotine in the treatment of various conditions susceptible to alleviation by nicotine therapy such as disease states characterized by reduced central cholinergic function. Nicotine is administered to a subject initially having a blood supply substantially free of nicotine at a dose and for a period sufficient to allow the subject to tolerate the dose and thereafter increasing the dose of nicotine at intervals until a therapeutic dose is achieved. Smokers may also benefit from the treatment regimen.Type: GrantFiled: January 5, 1990Date of Patent: December 3, 1991Assignee: Elan Corporation, PLCInventor: Joseph G. Masterson
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Patent number: 5064651Abstract: A process for the preparation of a hard candy containing an enzyme is disclosed, which comprises steps of preparing an unusual hard candy containing no enzyme, crushing the same into particles, mixing the enzyme with the candy particles, press treating the mixture to form a shaped mass, putting the mass into a pressure vessel, heating the vessel under pressurized inert gas to cause a partial melt of the mass, cooling the vessel to make the mass into the hard candy product, and releasing the pressure in the vessel.Type: GrantFiled: September 26, 1989Date of Patent: November 12, 1991Assignee: Meiji Seika Kaisha, Ltd.Inventors: Keizo Mochizuki, Naoki Sumi
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Patent number: 5061697Abstract: Sprayable, starch-based formulations for autoencapsulating biological control agents, such as pathogenic bacteria and viruses, incorporate a sugary material to promote adherence of the encapsulated agent to treated foliage. The autoencapsulated pathogens are characterized by high survivability and are useful in controlling insects and other pest species.Type: GrantFiled: August 3, 1989Date of Patent: October 29, 1991Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Baruch S. Shasha, Michael R. McGuire
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Patent number: 5059416Abstract: A new delivery system for zinc compounds and the process for its preparation is disclosed, which has use in a variety of products including comestibles such as chewing gum compositions, confections, pharmaceuticals, food products such as vitamin preparations, dentifrice compositions and throat lozenges. More particularly, this invention relates to a process for preparing a zinc compound delivery system comprised of a zinc core material coated with a first hydrophilic coating comprising a hydrocolloid material and a second hydrophobic coating selected from the group consisting of fats, waxes and mixtures thereof. The delivery system provides enhanced masking of the bitter flavor characteristic of zinc compounds, as well as reduced grittiness with retained stability at the elevated temperatures of product formulation.Type: GrantFiled: June 26, 1989Date of Patent: October 22, 1991Assignee: Warner-Lambert CompanyInventors: Subraman R. Cherukuri, Tommy L. Chau
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Patent number: 5055478Abstract: A method for eliminating an individual's tobacco smoking habit and associated nicotine dependence includes the step of gradually decreasing tobacco consumption over a first period of time until no further tobacco is consumed. This is done by first recording the individual's daily tobacco consumption. The day is broken down into consumption periods of one hour each. An alternative oral nicotine source is then progressively administered as a substitute for tobacco consumed during sequential consumption periods over each succeeding day for approximately two weeks until no further tobacco is consumed. Following a period during which the administration of the alternative nicotine source is maintained, it, too, is progressively eliminated over a period of approximately sixteen weeks.Type: GrantFiled: January 21, 1988Date of Patent: October 8, 1991Inventors: Thomas M. Cooper, Richard R. Clayton
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Patent number: 5049375Abstract: A colloidal solution comprises a fluoride(s) being difficultiy soluble in water comprises colloidal particles of the fluoride having a particle size of 0.005 to 1 micron, said fluoride having a fluoride ion concentration of 1 to 10,000 ppm in the state of saturation.Type: GrantFiled: May 24, 1990Date of Patent: September 17, 1991Assignee: Kao CorporationInventors: Satoshi Tsujita, Manabu Tonomura, Shigeto Kayane, Takashi Imamura
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Patent number: 5041429Abstract: Phytic acid or at least one of its salts is used as an effective component for cell activators in a hypoxic state, circulatory ameliorators, dementia remedies and edible compositions.Type: GrantFiled: May 22, 1989Date of Patent: August 20, 1991Assignee: Sanwa Kagaku Kenkyusho Co., Ltd.Inventors: Kiichi Sawai, Masayasu Kurono, Hiromoto Asai, Takahiko Mitani, Motohide Hayashi, Tunematu Suzuki, Naohisa Ninomiya
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Patent number: 5035882Abstract: The combination of pepper-like constituents, such as piperine, and volatile formate esters, such as ethyl formate, is useful as a substitute for chloroform in pharmaceutical, oral hygiene and confectionery compositions.Type: GrantFiled: April 12, 1990Date of Patent: July 30, 1991Assignee: Warner-Lambert CompanyInventors: Mamoun M. Hussein, Shirley A. Barcelon, Donald M. Lynch
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Patent number: 5034421Abstract: A spun product from a combination of a saccharide and a hydrophobic ingredient is hydrophilic with low concentrations of such ingredient but becomes increasingly hydrophobic as the concentration of the hydrophobic ingredient is increased, although the end product nevertheless acts hydrophilically when the water temperature is elevated. Larger ratios of hydrophobic substance-to-saccharide yields a spun fibrous product that has increased stability. Similar stabilization can be attained by adding either beeswax or a petrolatum to the saccharide either in the presence of or absence of a separate active ingredient. Examples are given for masking the taste of unpalatable medicaments or other ingestible substances. Delayed release burn or wound dressings are also described. Control with beeswax can also provide a time release tablet or the like when swallowed.Type: GrantFiled: March 20, 1989Date of Patent: July 23, 1991Assignee: Fuisz Pharmaceutical Ltd.Inventor: Richard C. Fuisz
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Patent number: 5028632Abstract: The addition of an extremely small quantity of an anesthetizing agent such as phenol to a medicament dosed saccharide floss serves to numb the taste buds sufficiently that undesirable taste stimulation by the medicament is inhibited.Type: GrantFiled: August 10, 1989Date of Patent: July 2, 1991Assignee: Fuisz Pharmaceutical Ltd.Inventor: Richard C. Fuisz
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Patent number: 5028412Abstract: Anti-calculus oral compositions include an aluminum salt and an aliphatic carboxylic acid or water-soluble salt thereof capable of complexing with the aluminum, together with a carrier suitable for use in the oral cavity. Such compositions exhibit marked effectiveness in inhibiting the formation and growth of calculus on the dental enamel.Type: GrantFiled: July 17, 1990Date of Patent: July 2, 1991Assignee: Purdue Research FoundationInventors: Mark S. Putt, Carl J. Kleber
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Patent number: 5019399Abstract: The present invention relates to a granular product, whereby it consists of a solid product, which has been provided with a coating of a water-soluble material, which has been provided as a melt, whereby the water-soluble products consists of one or more of polyethylene glycol, xylitol, sorbitol, lactitol, lecitin, and other water-soluble products, as well as a process for preparing the granular product.Type: GrantFiled: July 7, 1989Date of Patent: May 28, 1991Assignee: Lejus Medical AktiebolagInventors: Curt H. Appelgren, Ulf A. Odda
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Patent number: 5015477Abstract: The edible baked composition delivers cholestyramine in a palatable, pleasant tasting form. Embodiments include a nutrition bar and a cookie. The composition is useful for the control of endogenous cholesterol levels in humans.Type: GrantFiled: March 26, 1990Date of Patent: May 14, 1991Assignee: BASF K & F CorporationInventors: Thomas G. Wood, Carol J. Xenides
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Patent number: 5015474Abstract: Methods and compositions are provided for alleviating the dryness of a dermal or mucosal membrane substrate. The compositions are formulated from eriodictyon fluid which is a Yerba Santa extract and viscous excipients, and may be in the form of an aqueous vaginal douche, a cream or a suppository. The compositions may additionally contain a lubricant compound effective to provide lubrication and relieve frictional irritation on the affected area. Preservatives, topical anesthetics, coloring agents, emulsifiers, and the like may be included in the compositions as well. The Yerba Santa-based compositions of the invention are topically administered to an affected patient to alleviate the symptoms of dryness.Type: GrantFiled: March 26, 1990Date of Patent: May 14, 1991Assignee: Parnell Pharmaceuticals, Inc.Inventor: Francis W. Parnell
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Patent number: 5015467Abstract: Tartrate monosuccinate and tartrate disuccinate compounds of the formulae HO(CHCOOX)CH(COOX)OCH(COOX)CH.sub.2 COOX and CH.sub.2 (COOX)CH(COOX)O(CH[COOX]).sub.2 OCH(COOX)CH.sub.2 COOX are used in combination with various polymers to provide anticalculus and antiplaque effects on teeth. Oral care compositions such as dentifrices, mouthwashes, and the like, are provided. Use of the tartate-succinates and polymers in combination with other oral car ingredients such as fluoride, pyrophosphate and antibacterials is also described.Type: GrantFiled: June 26, 1990Date of Patent: May 14, 1991Assignee: The Procter & Gamble CompanyInventor: Herbert C. Smitherman
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Patent number: 5013554Abstract: Dextrorphan salts with polycarboxylic organic acids are effectively absorbed by the oral route and can conveniently be formulated in pharmaceutical compositions suitable to the oral administration.Type: GrantFiled: September 12, 1989Date of Patent: May 7, 1991Assignee: Prodotti Formenti s.r.l.Inventors: Carlos Passarotti, Antonio Fossati, Mauro Valenti, Gianluigi Bandi
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Patent number: 5013716Abstract: The present invention pertains to an unpleasant taste masking composition which comprises a flavoring agent having a bitter taste or unpleasant off-note and a sufficient amount of a non-bitter intense sweetener to nullify the taste or off-note of the flavoring agent. The unpleasant taste masking composition may be used in ingestible products such as hard and soft confections, chewing gum compositions and the like. The present invention also pertains to a method for preparing the unpleasant taste masking compositions and the ingestible products in which they may be used.Type: GrantFiled: October 28, 1988Date of Patent: May 7, 1991Assignee: Warner-Lambert CompanyInventors: Subraman R. Cherukuri, Lucy L. Wong, Steven M. Faust
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Patent number: 5009893Abstract: An edible composition capable of providing long-lasting, breath freshening perception without bitterness which comprises using in said edible composition a cooling composition comprising methanol and an N-substituted-p-methane carboxamide compound.Type: GrantFiled: July 17, 1989Date of Patent: April 23, 1991Assignee: Warner-Lambert CompanyInventors: Subraman R. Cherukuri, Krishna Raman, Gul Mansukhani, Ralph Cifrese, Lucy L. Wong