Abstract: Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.

Abstract: It has been found that toothpastes containing balance amounts of calcium based abrasive, copolymer of vinylmethylether and maleic acid and clay have significantly better stability even at elevated temperature. It has also been determined that the selected combination allows for complete removal of or at least a significant reduction in thickening silica, with almost no adverse effect on rheology. Disclosed is a toothpaste composition comprising: (i) a calcium based abrasive; (ii) a copolymer of vinylmethyl ether and maleic acid; and (iii) a clay, wherein ratio of the calcium based abrasive to said copolymer of vinylmethyl ether and maleic acid is at least 1:0075 and ratio of said calcium based abrasive to said clay is at least 1:0.02.

Abstract: Process for heat treating precipitated silica to improve stability. Oral care compositions comprising such heat treated precipitated silica abrasives and a stannous ion source.

Abstract: Provided is a toothpaste composition for dentin hypersensitivity that effectively prevents pain attributed to dentin hypersensitivity, instantaneously and sufficiently seals the openings of dentinal tubules in an exposed dentinal surface, and has excellent sustainability of the effect of suppressing the pain attributed to dentin hypersensitivity.

Abstract: A natural anhydrous oral care composition with a limited number of naturally-derived, naturally processed, generally regarded as safe (GRAS) ingredients including an effective amount of a bioactive glass is described. The topical application of the composition to human teeth cleanses, remineralizes and reduces plaque build-up on teeth.

Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.

Abstract: The application discloses a discus-shaped unit of a tablet or granulates which contain abrasive media, to be dissolved into a stream of water. Tablet or granulates are encased in a flexible, but inherently stable mesh of filaments for to enhance dissolution, avoid clogging nozzles and ease disposal of residues.

Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.

Abstract: Oral hygiene kits and methods of providing same are provided. The oral hygiene kit can include a tooth cleaning device, a food product and a xylitol-containing item selected from the group consisting of a candy, a chewing gum and a combination thereof. A method of reducing tooth decay in a student can include the steps of providing to the student an oral hygiene kit comprising a tooth cleaning device, a food product and a xylitol-containing item selected from the group consisting of a candy, a chewing gum and a combination thereof while the student is at school. In an embodiment, the food product does not have a low pH and/or does not have high fructose corn syrup.

Abstract: The invention provides a biological dressing for treatment of a dermatological disease comprised of one or more resins or other film-forming agents, a topically acceptable volatile solvent, and a pharmacologically active agent. The combined one or more resins are present in a suitable amount such that the composition, when the solvent evaporates, will dry to form a solid coating that sticks to the skin, nail or mucosal membrane to which the composition is applied, and maintain the pharmacologically active agent over a sustained period of time in contact with sites on the skin or mucosal membranes exhibiting symptoms of the disease. Methods are provided for treating symptoms of dermatological diseases with such a pharmacological composition.

Abstract: A therapeutic rinse for treating a sore throat including a self heating container having a reservoir. The self heating container is capable of reaching a temperature of at least 130 degrees Fahrenheit when activated. The therapeutic rinse includes a liquid composition having sodium chloride, water, an antibiotic, and a variety of vitamins, minerals and herbs stored in the reservoir of the self heating container. During use, the self heating container is activated and the liquid composition is heated inside the reservoir to about 130 degrees Fahrenheit.

Abstract: A composition for endodontic irrigation is provided. The composition includes a chemical depilatory during intra-canal, and chemo-mechanical instrumentation in endodontic. The composition includes calcium hydroxide or potassium hydroxide, sodium hydroxide, and potassium thioglycolate or calcium thioglycolate to form an effective root canal medicament. Further, the composition may incorporate mineral oil, urea, cetearyl alcohol, D&C yellow No. 8, chromium hydroxide, theobroma cocoa seed butter, iron oxides, fragrances, and ceteareth-20 to enhance its functioning. The composition disinfects, lubricates, chelates, irrigants, dissolves, and facilitates removal of the pulpal tissue and debris. Furthermore, the composition reduces and even eliminates bacteria from micro-endodontic systems. Further, the composition of the present invention enhances eradicating pathogens along with chemo-mechanical debridement of the root canal system.

Abstract: Improved remineralizing and desensitizing compositions containing remineralizing ingredients in aqueous-free emulsions that, in the presence of saliva, form mucoadhesive gels substantive to tooth surfaces; wherein the gels are dissolved by saliva gradually releasing remineralizing ingredients onto tooth surfaces, treatments with these compositions and methods of manufacture.

Abstract: A homeopathic composition and method for treating a variety of skin irritations, wounds, and diseases is disclosed. The homeopathic composition may contain as active ingredients salicyclic acid, trona or one of its salts, and at least one homeopathic agent.

Abstract: Processes for improving the taste of water-soluble surfactants using liquid-liquid solvent extraction, said process comprising the steps of: providing a water-soluble surfactant composition in need of treatment wherein said water-soluble surfactant composition comprises a water-soluble surfactant and one or more undesirable non-polar materials; contacting said water-soluble surfactant composition with an extraction solvent and water to form an extraction mixture comprising an aqueous phase and a solvent phase; and separating the aqueous phase from the solvent phase; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (?D) ranging from about 15 to about 17 (MPa)0.5, a polar component (?P) ranging from 0 to about 9 (MPa)0.5 and a hydrogen bonding component (?H) ranging from 0 to about 11 (MPa)0.5.

Abstract: Processes for improving the taste of water-soluble surfactants using liquid-liquid solvent extraction, said process comprising the steps of: providing a water-soluble surfactant composition in need of treatment wherein said water-soluble surfactant composition comprises a water-soluble surfactant and one or more undesirable non-polar materials; contacting said water-soluble surfactant composition with an extraction solvent and water to form an extraction mixture comprising an aqueous phase and a solvent phase; and separating the aqueous phase from the solvent phase; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (?D) ranging from about 15 to about 17 (MPa)0.5, a polar component (?P) ranging from 0 to about 9 (MPa)0.5 and a hydrogen bonding component (?H) ranging from 0 to about 11 (MPa)0.5.

Abstract: The present invention provides a recombinant fusion protein which stimulates the rejuvenation and reactivation of skin and epidermal cells for improving skin appearance, smoothing wrinkles and freckles, and whitening skin. Particularly, the present invention provides various types of products for improving skin, which contain recombinant fusion protein of human serum albumin (HSA) with cytokine peptides (EGF, FGF, KGF, HGH, HGF, PDGF, GCSF, interferon, IL-11 or IGF) by genetic engineering technology. The fusion protein can be used independently or in a combination or combination with yeast fermentation products, or with varied emulsifiers, thickeners, moisturizer, preservatives, yeasts and ferments.

Abstract: Presently described are dental compositions comprising one or more fatty mono(meth)acrylates, methods of use, dental articles, and methods of making dental compositions. It has been found that a relatively low concentration of a fatty mono(meth)acrylate can improve the handling characteristics of a dental composition by reducing the tendency of the composition to stick to a dental instrument and/or by reducing the tendency of a dental composition to string when being manipulated by a dental instrument. In one embodiment, a hardenable dental composition is described comprising a polymerizable resin composition comprising at least one multifunctional ethylenically unsaturated monomer; 0.2 to 10 wt-% of one or more fatty mono(meth)acrylate monomers; and at least 50 wt-% of inorganic oxide filler.

Abstract: The present invention is directed to improved sweetener compositions and oral care compositions, especially those in the form of a toothpaste or oral/dental rinse, comprising the same. The sweetener composition comprises a combination of saccharin, sucralose and a rebaudioside, or sweeteners of similar sucrose equivalence and type, preferably in a ratio of about 1:about 1: about 2. The sweetener composition of the invention was found to significantly improve the taste profile, long lasting freshness and clean feel of oral care compositions and to deliver an in-use sweetness that was more natural and pleasant than artificial sweeteners alone.

Abstract: EDTA and EDTA related compositions and methods of using them are described herein. The compositions can have improved bioavailability over EDTA alone. The compositions can be useful in the treatment or prevention of atherosclerosis or for the treatment of heavy metal accumulation.

Abstract: Methods for inhibiting the development of respiratory infections in humans are disclosed.

Abstract: The use of hesperetin of formula (I) is described wherein the hesperetin of formula (I) is in the form of a (2S)-enantiomer, (2R)-enantiomer or any desired mixture of the two enantiomers, a salt of hesperetin of formula (I), —a mixture comprising or consisting of two or more salts of the hesperetin of formula (I), or a mixture comprising or consisting of hesperetin of formula (I) and one or more salts of hesperetin of formula (I) for enhancing the sweet taste of a sweet-tasting substance or sweet olfactory impression of a flavoring which gives a sweet olfactory impression.

Abstract: The present invention is directed towards a composition for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an enamel repairing composition such as hydroxyapatite. The composition can contain from about 10% up to 90% of ascorbic acid without compromising the tooth enamel because hydroxyapatite will repair any damage to the enamel. The composition can be used as dental powder, toothpaste, mouthwash, mouth spray and chewing gum in order to cover a wide range of consumers in different settings.

Abstract: The present invention relates to an oral care composition, which contains the following components (A), (B) and (C): (A) an inorganic acid and/or an organic acid, (B) an anionic surfactant, (C) at least one compound selected from polyglycerin fatty acid esters, sorbitan fatty acid esters, polyoxyethylene higher alcohol ethers having from 6 to 14 carbon atoms, polyoxyethylene fatty acid esters and polyoxyethylene polyoxypropylene copolymers. The oral care composition according to the present invention is significantly excellent in reducing astringency and bitterness inherent in anionic surfactants.

Abstract: The present invention relates to tooth sensitivity treatment compositions, including mouth rinses, comprising C2-C5 diacid, triacid or tetraacid salts and a tastemasking agent(s). Methods for using the compositions are also disclosed.

Abstract: Disclosed herein is a continuous process for preparing a silica product, comprising: (a) continuously feeding an acidulating agent and an alkali metal silicate into a loop reaction zone comprising a stream of liquid medium; wherein at least a portion of the acidulating agent and the alkali metal silicate react to form a silica product in the liquid medium of the loop reaction zone; (b) continuously recirculating the liquid medium through the loop reaction zone; and (c) continuously discharging from the loop reaction zone a portion of the liquid medium comprising the silica product. Silica products and dentifrice compositions comprising the silica products are also disclosed. A continuous loop reactor is also disclosed.

Abstract: Compositions containing ferrate(VI) are disclosed. Also, methods are disclosed that utilize ferrate(VI).

Abstract: The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precusors. Further the invention relates to compositions, comprising the precursor of the invention.

Abstract: The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being, of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precusors. Further the invention relates to compositions, comprising the precursor of the invention.

Abstract: The present invention relates to multicomponent glasses and their use in powdered form as an additive in personal care products such as toothpastes.

Abstract: Nanoparticulate material containing a matrix and embedded therein a radiopacifier are bioactive, show a high alkaline capacity and are radio-opaque. Compositions and formulations including such material are particularly useful in advanced dental applications, such as dental fillings and/or disinfection.

Abstract: This invention comprises a set of dental products and methods to prevent and treat dentinal hypersensitivity, prevent tooth decay, and heal incipient caries by means of Mouth Friendly® dental products containing calcium carbonate, having a preferred particle size of 1 to 100 nanometers (nm), and a preferred weight range of 5 to 30%. Said products must contain 8 to 95 weight percent of xylitol, plus the surfactant system described in U.S. Pat. No. 5,496,541 (Mar. 5, 1996) and U.S. Pat. No. 5,900,230 (May 4, 1999). It is further required that all irritants and other mouth unfriendly ingredients be absent from the dental products of this invention. Additional features of this invention include prevention and treatment of aphthous ulcers, oral mucositis, periodontal disease, perioral dermatitis, halitosis, oral candida, chapped lips, and oral plaque and tartar. This invention also ameliorates the condition of those who suffer from xerostomia and cold sores.

Abstract: This invention concerns a method of improving penetration of compositions to dentin, enamel, dental pulp or cement and dental compositions for restoration or decoration of teeth, for use in pulp medication comprising, for root canal disinfection and/or obturation and for desensitizing. This invention also concerns uses of DMSO for improving the bond strength of dental composition and in preparing dental compositions. Further the invention concerns a new method of treating teeth so that penetration of components is increased.

Abstract: Antiplaque oral compositions are provided that contain an orally acceptable carrier and an antibacterial effective amount of the compound of formula (I). In various embodiments, the compositions contain from about 0.001% to about 10% by weight of the compound of formula (I).

Abstract: The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.

Abstract: Disclosed herein is a pair of dry type patches for teeth whitening, having a patch for upper teeth and a patch for lower teeth, in which the patch for upper teeth has a shape different from the patch for lower teeth, and each patch has a controlled width and shape such that the contact area of each patch with gums is minimized. In the patch for upper teeth, a central portion covering right and left upper central incisors is widest. In the patch for lower teeth, either portion covering right and left lower canine teeth is widest. Since the dry type patches covers all the portions of the teeth while minimizing the contact area with gums, no or little irritation is caused and wearability is excellent.

Abstract: A hybrid encapsulate formulation obtained by mixing a starch/fragrance emulsion with a core-shell capsule suspension is provided as is a method of using the formulation in a personal care product, a beauty care product, a fabric care product, a home care product, a personal hygiene product, an oral care product and a method for releasing an encapsulated fragrance by moisture, shear, or a combination thereof.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.

Abstract: A flowable, stable silica capsule formulation composed of a silica capsule suspension and an adjuvant for use in a personal care product, a beauty care product, a fabric care product, a home care product, a personal hygiene product, an oral care product is provided.

Abstract: A composition is provided, wherein the composition comprises a water-swellable, water-insoluble polymer or a water-soluble polymer, a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding to the hydrophilic polymer. The composition also includes a second water-swellable, water-insoluble polymer that provides for a phase separating film forming composition. Active ingredients, such as a whitening agent, may be included. The composition finds utility as an oral dressing, for example, a tooth whitening composition that is applied to the teeth in need of whitening, and removed when the degree of whitening has been achieved. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed.

Abstract: The invention relates to personal care products containing multilayer films with decorative layers and may impart a noticeable color change. The invention is applicable in products including type toothpaste, soaps, and other products until diluted with water (or saliva).

Abstract: A device that may be placed on a fingertip for treating an oral cavity. The device may be made from a material comprised of at least one ingredient for treating an oral cavity. Examples of ingredients for treating an oral cavity include abrasives, cavity prevention ingredients, medicinal ingredients (e.g., antiseptics, fungicides, and anesthetics), odor absorbing ingredients, tartar control ingredients, plaque control ingredients, tooth whitening ingredients, ingredients adapted to provide relief from hypersensitivity, and other cleaning ingredients and dentifrices. The device may be dissolvable and edible. Furthermore, some or all of the ingredients may be digestible. For example, the device may be primarily or entirely made of ingredients that are digestible.

Abstract: A two-step system for whitening stained or discolored teeth by applying separately, and sequentially, to the teeth (i) a bleaching activator followed by (ii) a bleaching agent. In preferred embodiments the bleaching activator is a transition metal catalyst and the bleaching agent is a peroxide.

Abstract: Processes for improving the taste of oral care raw materials using solvent extraction, said process comprising the steps of: providing a solid oral care raw material composition in need of treatment wherein said oral care raw material composition comprises an orally acceptable raw material and one or more undesirable non-polar materials; contacting said oral care raw material composition with an extraction solvent to form an extraction mixture comprising a solid phase and a solvent phase; and separating the solid phase from the extraction mixture; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (?D) ranging from about 15 to about 17 (MPa)0.5, a polar component (?P) ranging from 0 to about 9 (MPa)0.5 and a hydrogen bonding component (?H) ranging from 0 to about 11 (MPa)0.5.

Abstract: A two-step system for whitening stained or discolored teeth by applying separately, and sequentially, to the teeth (i) a bleaching activator followed by (ii) a bleaching agent. In preferred embodiments the bleaching activator is a transition metal catalyst and the bleaching agent is a peroxide.

Abstract: The present invention provides new methods for inducing or promoting bone growth and/or for reducing or preventing bone deterioration in a mammal subject. The inventive methods generally comprise administering to the subject an effective amount of a resolvin. In particular, the inventive methods may be useful for treating or preventing conditions associated with bone degradation, deterioration or degeneration such as periodontal disease, osteoarthritis, and metastatic bone disease and osteolytic bone disease. Pharmaceutical compositions and kits comprising at least one resolvin are also provided that can be used to performed the inventive methods.

Abstract: An oral care composition which is a liquid at or below room temperature and which forms a two-phase cloudy system at body temperature and wherein the composition comprises a water-soluble non-ionic polymer, such as HPC, having a cloud point in the composition at a temperature no higher than about 38° C., for combating (i.e. helping to prevent, inhibit and/or treat) dentinal hypersensitivity.

Abstract: A tooth sensitivity treatment composition is disclosed. The composition includes a compound of formula I M1-A-M2-B-M1??(I) wherein: M1 is a monovalent or divalent metal; M2 is a polyvalent metal or metal oxide; and A and B are, independently, selected from the group consisting of C2-C6 diacids, triacids, and tetraacids. Methods for treating tooth sensitivity are also disclosed.

Abstract: The present disclosure embrace Blue Curls (Trichostema lanatum) var. Pirzada and compositions and methods there from. Specifically, the applications provides methods and compositions relating to Blue Curls Pirzada essential oil and floral water.

Abstract: The invention includes a dentifrice composition that comprises a zinc ion source, a polyphosphate ion source, an anethole, and a silica. The silica has a mean particle size of about 5 to about 12 microns, an Einlehner hardness of about 1 to about 20, and an oil absorption of about 40 to less than about 100 cc/100 g. The composition contains zinc ions and polyphosphate ions in a weight ratio of about 0.1:1 to about 10:1 and has a RDA value of about 100 to about 200 and a PCR value of about 75 to about 110. Related methods are also included.