Tricyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos Patents (Class 546/79)
  • Patent number: 8828561
    Abstract: A compound for an organic photoelectric device, the compound being represented by the following Chemical Formula (“CF”) 1:
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: September 9, 2014
    Assignee: Cheil Industries, Inc.
    Inventors: Hyung-Sun Kim, Eun-Sun Yu, Young-Hoon Kim, Ja-Hyun Kim, Soo-Hyun Min, Ho-Jae Lee, Eui-Su Kang, Mi-Young Chae
  • Patent number: 8785003
    Abstract: An organic EL device material includes at least a unit including 3,5-biscarbazolylphenyl group, a unit including 4-carbazolylphenyl group, and a compound including a unit including a nitrogen-containing aromatic heterocyclic ring bonding the unit including 3,5-biscarbazolylphenyl group and the unit including 4-carbazolylphenyl group.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: July 22, 2014
    Assignee: Idemtisu Kosan Co., Ltd.
    Inventors: Tetsuya Inoue, Kumiko Hibino, Kei Yoshida, Kazuki Nishimura, Toshihiro Iwakuma
  • Patent number: 8785001
    Abstract: The present invention relates to mixtures of organic materials, to the use of these mixtures in organic electroluminescent devices, and to organic electroluminescent devices comprising these mixtures.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: July 22, 2014
    Assignee: Merck Patent GmbH
    Inventors: Horst Vestweber, Philipp Stoessel, Holger Heil
  • Patent number: 8771845
    Abstract: Disclosed herein are compounds represented by Formula 1, wherein R1, Ar1, X, Ar2, Ar3, and Het are described herein. Compositions and light-emitting devices related thereto are also disclosed.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: July 8, 2014
    Assignee: Nitto Denko Corporation
    Inventors: Shijun Zheng, Jensen Cayas, Sheng Li, Amane Mochizuki, Hyun Sik Chae, Brett T. Harding
  • Patent number: 8771840
    Abstract: Provided are a heterocyclic compound which emits blue light and is represented by General Formula (G1) below, and a light-emitting element, a light-emitting device, an electronic device and a lighting device which are formed using the heterocyclic compound represented by General Formula (G1) below. The use of the heterocyclic compound represented by General Formula (G1) makes it possible to provide a light-emitting element which has high emission efficiency, and also a light-emitting device, an electronic device and a lighting device which have reduced power consumption.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: July 8, 2014
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventors: Hiroki Suzuki, Tsunenori Suzuki, Satoshi Seo
  • Patent number: 8771844
    Abstract: A heterocyclic compound, an organic light-emitting diode, and a flat display device, the heterocyclic compound being represented by Formula 1, below:
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: July 8, 2014
    Assignee: Samsung Display Co., Ltd.
    Inventors: Young-Kook Kim, Seok-Hwan Hwang, Hye-Jin Jung, Jin-O Lim, Sang-Hyun Han, Yoon-Hyun Kwak, Sun-Young Lee, Se-Jin Cho, Jong-Hyuk Lee, Sung-Chul Kim
  • Patent number: 8748014
    Abstract: The present invention relates to a compound having a substituted anthracene ring structure and a pyridoindole ring structure, which is represented by the following general formula (1) or the following general formula (2); and an organic electroluminescent device having a pair of electrodes and at least one organic layer interposed therebetween, in which the compound having a substituted anthracene ring structure and a pyridoindole ring structure, which is represented by the following general formula (1) or the following general formula (2), is used as a constituent material of the aforementioned at least one organic layer.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: June 10, 2014
    Assignee: Hodogaya Chemical Co., Ltd.
    Inventors: Norimasa Yokoyama, Shuichi Hayashi, Kouki Kase, Hiroshi Ohkuma, Eiji Takahashi, Daizou Kanda
  • Patent number: 8748012
    Abstract: Novel aryl silicon and aryl germanium host materials are described. These compounds improve OLED device performance when used as hosts in the emissive layer of the OLED.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: June 10, 2014
    Assignee: Universal Display Corporation
    Inventors: Lichang Zeng, Alexey B. Dyatkin, Gregg Kottas
  • Patent number: 8741446
    Abstract: Organic compounds and organic electroluminescent devices employing the same are provided.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: June 3, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Jin-Sheng Lin, Meng-Ting Lee, Heh-Lung Huang
  • Publication number: 20140128400
    Abstract: Bridged bicyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
    Type: Application
    Filed: January 8, 2014
    Publication date: May 8, 2014
    Applicant: Rigel Pharmaceuticals, Inc.
    Inventors: Rajinder Singh, Sacha Holland, Joane Litvak, Dane Goff, Jing Zhang, Thilo J. Heckrodt
  • Publication number: 20140128367
    Abstract: The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
    Type: Application
    Filed: June 14, 2012
    Publication date: May 8, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Xianhai Huang, Jason Brubaker, Scott L. Peterson, John W. Butcher, Joshua T. Close, Michelle Martinez, Rachel Nicola MacCoss, Joon O. Jung, Phieng Siliphaivanh, Hongjun Zhang, Robert G. Aslanian, Purakkattle Johny Biju, Li Dong, Ying Huang, Kevin D. McCormick, Anandan Palani, Ning Shao, Wei Zhou
  • Patent number: 8709743
    Abstract: The invention relates in part to compounds that act as highly nitric oxide (NO)-specific turn-on fluorescent probes. The present invention also relates to the use of these fluorescein-based sensors to screen selectively for inhibitors of bacterial nitric oxide synthase (bNOS). Compounds of the present invention readily detect nitric oxide produced in vivo. Therefore they can be used in an assay that measures NO production by bNOS. Using a sensor of the invention one can screen libraries of small molecules for inhibitors of bNOS.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: April 29, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen J. Lippard, Lindsey E. McQuade, Evgeny A. Nudler
  • Patent number: 8703300
    Abstract: Disclosed is a long-life organic electroluminescent element which can be driven at low voltage. Also disclosed are a display and illuminator using the same. Specifically disclosed is an organic electroluminescent element comprising on a substrate, an anode, a cathode and an organic compound layer arranged between the anode and the cathode and including at least one light emission layer. This organic electroluminescent element is characterized in that the organic compound layer includes an electron transport material-containing layer which contains an electron transport material represented by Formula (a) and at least one substance selected from the group consisting of metals, salts of the metals and electron-donating compounds. Formula (a) Ar1-(Ar2)n [In the formula, Ar1 represents a group derived from an aromatic hydrocarbon ring or a group derived from an aromatic heterocycle; Ar2 represents a group derived from an aromatic heterocycle; and n represents an integer of 2 or more.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: April 22, 2014
    Assignee: Konica Minolta Holdings, Inc.
    Inventors: Yoshiyuki Suzuri, Akira Kawakami, Hiroshi Kita
  • Patent number: 8697255
    Abstract: The present invention relates to an organic light-emitting diode comprising an anode and a cathode Ka and a light-emitting layer E and if appropriate at least one further layer, where the light-emitting layer E and/or the at least one further layer comprises at least one compound selected from disilylcarbazoles, disilyldibenzofurans, disilyldibenzothiophenes, disilyldibenzophospholes, disilyldibenzothiophene S-oxides and disilyldibenzothiophene S,S-dioxides, to a light-emitting layer comprising at least one of the aforementioned compounds, to the use of the aforementioned compounds as matrix material, hole/exciton blocker material, electron/exciton blocker material, hole injection material, electron injection material, hole conductor material and/or electron conductor material, and to a device selected from the group consisting of stationary visual display units, mobile visual display units and illumination units comprising at least one inventive organic light-emitting diode.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: April 15, 2014
    Assignee: BASF SE
    Inventors: Nicolle Langer, Klaus Kahle, Christian Lennartz, Oliver Molt, Evelyn Fuchs, Jens Rudolph, Christian Schildknecht, Soichi Watanabe, Gerhard Wagenblast
  • Patent number: 8685543
    Abstract: A material for electroluminescent devices which comprises a compound in which a heterocyclic group having nitrogen is bonded to carbazolyl group and an organic electroluminescent device having at least one organic thin film layer which is sandwiched between the cathode and the anode and contains the above material in at least one layer, are provided. The material can provide organic electroluminescent devices emitting bluish light with a high purity of color. The organic electroluminescence device uses the material.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: April 1, 2014
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Toshihiro Iwakuma, Chishio Hosokawa, Hidetsugu Ikeda, Seiji Tomita, Takashi Arakane
  • Patent number: 8679647
    Abstract: The invention relates to organic electroluminescent devices which comprise triazine derivatives as the electron transport material.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: March 25, 2014
    Assignee: Merck Patent GmbH
    Inventors: Christof Pflumm, Simone Leu, Joachim Kaiser, Amir Hossain Parham, Frank Voges, Jonas Valentin Kroeber, Arne Buesing
  • Patent number: 8679645
    Abstract: The present invention relates to novel materials which can be used in organic electronic devices, in particular electroluminescent devices, and are certain derivatives of fused aromatic systems.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: March 25, 2014
    Assignee: Merck Patent GmbH
    Inventors: Holger Heil, Arne Buesing, Philipp Stoessel, Horst Vestweber
  • Patent number: 8679648
    Abstract: A heterocyclic compound represented by Formula 1 below and an organic light-emitting diode (OLED) including the same: wherein R1 through R12, Ar1, Ar2, A, B, a, and b are the same as defined above. An OLED including an organic layer including the heterocyclic compound has low driving voltage, high luminous efficiency, and a long lifetime.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: March 25, 2014
    Assignee: Samsung Display Co., Ltd.
    Inventors: Sang-Hyun Han, Seok-Hwan Hwang, Young-Kook Kim, Hye-Jin Jung, Jin-O Lim, Soo-Yon Kim, Il-Soo Oh, Jong-Hyuk Lee
  • Publication number: 20140080788
    Abstract: Novel compounds of Formula I:or an enantiomer, diastereomer, tautomer, prodrug or salt thereof, wherein m, Q, T, U, V, ring A, X, Y, R3, R4, R4a, R5a, R5b, R5c, R5d, R5e, R6a, R6b, and R6c are defined herein, are provided which are TGR5 G protein-coupled receptor modulators. TGR5 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring TGR5 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the TGR5 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
    Type: Application
    Filed: April 27, 2012
    Publication date: March 20, 2014
    Inventors: Jeffrey A. Robl, Jun Li, Lawrence J. Kennedy, Steven J. Walker, Haixia Wang, William N. Washburn, Saleem Ahmad, Khehyong Ngu
  • Patent number: 8653097
    Abstract: The present invention encompasses compounds of general formula (1) wherein R1 to R4, A, X, m and k are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
    Type: Grant
    Filed: October 15, 2009
    Date of Patent: February 18, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Lars Van Der Veen, Darryl McConnell, Tobias Wunberg
  • Publication number: 20140045746
    Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.
    Type: Application
    Filed: July 31, 2013
    Publication date: February 13, 2014
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: William K. Hagmann, Ravi P. Nargund, Timothy A. Blizzard, Hubert Josien, Purakkattle Biju, Christopher W. Plummer, Qun Dang, Bing Li, Linus S. Lin, Mingxiang Cui, Bin Hu, Jinglai Hao, Zhengxia Chen
  • Publication number: 20140045793
    Abstract: The present invention provides a quinolone compound that inhibits the chronic progression of Parkinson's disease or protects dopamine neurons from disease etiology, thereby suppressing the progression of neurological dysfunction, so as to prolong the period of time until L-dopa is administered while also improving neuronal function; the quinolone compound of the invention is represented by Formula (1): wherein: R1 represents hydrogen or the like; R2 represents hydrogen or the like; R3 represents substituted or unsubstituted phenyl or the like; R4 represents halogen or the like; R5 represents hydrogen or the like; R6 represents hydrogen or the like; and R7 represents hydrogen or the like.
    Type: Application
    Filed: October 18, 2013
    Publication date: February 13, 2014
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Kenji OTSUBO, Takahito YAMAUCHI, Yuji OCHI
  • Publication number: 20140038883
    Abstract: The present invention relates to compounds of formula (I), where R1 and R2, identical or different, are each independently a hydrogen atom or a non-substituted or substituted (C1-C12) alkyl group; R3 is a hydrogen atom or a non-substituted or substituted (C1-C6) alkyl group; R4 is a non-substituted or substituted (C1-C12) alkyl group or an aryl or heteroaryl group, said aryl and heteroaryl groups being non-substituted or substituted; and R5 is a non-substituted or substituted (C1-C12) alkyl group; or R4 and R5 are bonded to one another by a saturated hydrocarbon chain having 3 or 4 carbon atoms, optionally in hydrated form or in the form of a salt that is acceptable for being administered to animals or plants, for the use thereof as a potentiator of the effect of an antimicrobial agent or for the use thereof as an antimicrobial agent.
    Type: Application
    Filed: January 27, 2012
    Publication date: February 6, 2014
    Applicants: UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITE JOSEPH FOURIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, HOSPICES CIVIL DE LYON
    Inventors: Anne Doleans-Jordheim, Jean Freney, Charles Dumontet, Ahcene Boumend Jel, Jean-Baptiste Veron, Yung-Sing Wong
  • Patent number: 8642188
    Abstract: In OLEDs, improved efficiency is obtained by using compounds of formula [Ar](CH?CH—R1)n wherein n is an integer from 1 to 4; [Ar] is a polycyclic aromatic or heteroaromatic scaffold optionally substituted with one or more alkyl or alkoxy groups; and R1 is a 5-membered heteroaryl group optionally substituted with methyl, methoxy, aryl or heteroaryl, or is phenyl or naphthyl optionally substituted with methyl, methoxy, trifluoromethyl or cyano or is biphenyl or substituted biphenyl. The compounds are believed to be novel and can be made by condensing a compound of formula wherein [Ar] and n are as defined above with a compound of formula [Ar](CH3)nR1CHO in the presence of an acid catalyst e.g. an anhydride of an organic acid.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: February 4, 2014
    Assignee: Merck Patent GmbH
    Inventors: Poopathy Kathirgamanathan, Sivagnanasundram Surendrakumar
  • Patent number: 8642764
    Abstract: Compounds that selectively bind to copper ions in a sample and methods of preparing and using the compounds are described. Disclosed herein are planar julolidine based compounds that display characteristic absorbance in the visible and near-infrared (NIR, 700-1000 nm) region in the presence of copper ions. Methods to detect Cu2+ ions by fluorometry and colorimetry are disclosed.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: February 4, 2014
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Govindaraju Thimmaiah, Debabrata Maity, Swapan Kumar Pati, Tapas Kumar Kundu, Arun Kumar Manna, Karthigeyan Dhanasekaran
  • Patent number: 8642189
    Abstract: The invention provides an organic compound which shows an excellent electron-injecting/transporting performance, has a hole-blocking ability and shows a high stability as a film, that is, having excellent characteristics as a material for organic electroluminescent device having high efficiency and high durability; and provides an organic EL device comprising the compound and having high efficiency and high durability.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: February 4, 2014
    Assignees: Hodogaya Chemical Co., Ltd., Shinshu University, National University Corporation
    Inventors: Norimasa Yokoyama, Shuichi Hayashi, Makoto Nagaoka, Yoshio Taniguchi, Musubu Ichikawa
  • Patent number: 8637496
    Abstract: The invention relates to the use of compounds having a monogalactosyldiacylglycerol (MGDG) synthase inhibitory activity as herbicide or algaecide, and to herbicide and algaecide compositions containing at least one of these compounds.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: January 28, 2014
    Assignees: Commissariat a l'Energie Atomique, Centre National de la Recherche Scientifique
    Inventors: Anne-Laure Bonneau, Cyrille Botte, Michael Deligny, Nadia Saidani, Hélène Hardre, Bernard Rousseau, Roman Lopez, Eric Marechal
  • Patent number: 8633316
    Abstract: Provided is a method for producing a nitrogen-containing condensed heterocyclic compound containing the step of: reacting a compound represented by Formula (1a) or Formula (1b) with a compound represented by Formula (2) under existence of cupper or a cupper ion, and a ligand to produce a nitrogen-containing condensed heterocyclic compound represented by Formula (3a) or Formula (3b):
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: January 21, 2014
    Assignee: Konica Minolta Holdings, Inc.
    Inventors: Shuichi Sugita, Eisaku Katoh, Rie Fujisawa
  • Patent number: 8623521
    Abstract: A heterocyclic compound, an organic light-emitting diode, and a flat display device, the heterocyclic compound being represented by Formula 1, below:
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: January 7, 2014
    Assignee: Samsung Display Co., Ltd.
    Inventors: Young-Kook Kim, Seok-Hwan Hwang, Hye-Jin Jung, Jin-O Lim, Sang-Hyun Han, Yoon-Hyun Kwak, Sun-Young Lee, Hee-Joo Ko, Jong-Hyuk Lee, Sung-Chul Kim
  • Patent number: 8617722
    Abstract: The present invention provides a polymer material capable of preparing organic EL elements having low driving voltage and high durability. The polymer compound of the present invention includes a constituting unit derived from a monomer represented by the formula (1); (in the formula (1), each of A1's is independently a condensed polycyclic aromatic group optionally having a heteroatom as a ring-constituting atom; the condensed polycyclic aromatic group links to A2 at the meta position to the bonding position of the ring represented by the following formula; each of A2's is independently a six-membered ring aromatic group optionally having a heteroatom as a ring-constituting atom; at least one of A1 and A2 has a substituent having a polymerizable functional group; at least one of X's is a nitrogen atom, and n's are independently 1 or 2).
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: December 31, 2013
    Assignee: Showa Denko K.K.
    Inventors: Masahiko Toba, Tsuyoshi Kato
  • Patent number: 8614011
    Abstract: An electroluminescent material comprises the following structural unit: where X is selected from a group consisting of NR, O, S, SO, SO2, CR2, PR, POR, BR, SiR2; where R is a substituent group and Ar1 and Ar2 comprise aromatic rings; and, wherein Ar1 or Ar2 is fused to a further aryl system Ar3. An optical device comprises a first electrode for injection of positive charge carriers, a second electrode for injection of negative charge carriers and a layer located between the first and second electrode comprising the electroluminescent material.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: December 24, 2013
    Assignees: Cambridge Display Technology Limited, Sumitomo Chemical Co., Ltd.
    Inventors: Annette Steudel, Thomas Pounds
  • Patent number: 8597802
    Abstract: Disclosed are an acridine derivative and an organic electro-luminescence device including the same. Specifically, the disclosed acridine derivative compound has an aryl moiety or a heteroaryl moiety, linked to an acridine moiety and an amine moiety, and the disclosed organic electro-luminescence device including the acridine derivative compound requires a low operating voltage, shows high efficiency, and is enhanced in life-span.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: December 3, 2013
    Assignee: Doosan Corporation
    Inventors: Tae-Hyung Kim, Kyoung-Soo Kim
  • Patent number: 8592383
    Abstract: The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: November 26, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Xianhai Huang, Jason Brubaker, Scott L. Peterson, John W. Butcher, Joshua T. Close, Michelle Martinez, Rachel Nicola MacCoss, Joon O. Jung, Phieng Siliphaivanh, Hongjun Zhang, Robert G. Aslanian, Purakkattle Johny Biju, Li Dong, Ying Huang, Kevin D. McCormick, Anandan Palani, Ning Shao, Wei Zhou
  • Patent number: 8586210
    Abstract: The present invention provides an organic compound having excellent properties, which is excellent in electron-injection/transport performance, has hole-blocking ability and is high stability in a thin-film state, as a material for an organic electroluminescence device having a high efficiency and a high durability, and provides is an organic electroluminescence device having a high efficiency and a high durability using the compound. The present invention relates to a compound having a substituted anthracene ring structure and a pyridoindole ring structure represented by general formula (1); and an organic electroluminescence device having a pair of electrodes and at least one organic layer interposed between the electrodes in which the at least one organic layer contains the compound.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: November 19, 2013
    Assignee: Hodogaya Chemical Co., Ltd.
    Inventors: Norimasa Yokoyama, Shuichi Hayashi, Sawa Izumi, Naoaki Kabasawa, Shigeru Kusano
  • Patent number: 8586746
    Abstract: The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Radiolabelled compounds useful for evaluating the binding affinity to ?7 nicotinic acetylcholine receptors also are described.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: November 19, 2013
    Assignee: AbbVie Inc.
    Inventors: Michael R. Schrimpf, Kevin B. Sippy, David J. Anderson, William H. Bunnelle, Diana L. Nersesian
  • Patent number: 8586200
    Abstract: Disclosed is an organic compound represented by the following Chemical Formula 1 that easily dissolves in an organic solvent, and that is applicable as a host material of an emission layer of an organic photoelectric device since it emits fluorescence and phosphorescence at a red wavelength through a blue wavelength.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: November 19, 2013
    Assignee: Cheil Industries, Inc.
    Inventors: Sung-Hyun Jung, Hyung-Sun Kim, Ho-Jae Lee, Eun-Sun Yu, Mi-Young Chae
  • Patent number: 8580403
    Abstract: According to one embodiment, there is provided an organic light-emitting diode including an anode and a cathode which are arranged apart from each other, and an emissive layer interposed between the anode and the cathode and including a host material and an emitting dopant. The host material includes a polymer containing dibenzothiophene backbones represented by the following formula (1) as repeating units: wherein n is an integer of from 20 to 10,000.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: November 12, 2013
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Yukitami Mizuno, Isao Amemiya, Akiko Hirao, Isao Takasu, Tomoko Sugizaki, Akio Amano, Yasushi Shinjo, Tomoaki Sawabe, Shintaro Enomoto
  • Patent number: 8580396
    Abstract: The present invention relates to novel carbazole derivatives and an organic light-emitting diode device using the same. These carbazole derivatives can simultaneously or singly be used as a hole transporting layer, a host or guest of an emitting layer or an electron transporting layer of an organic light-emitting diode device.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: November 12, 2013
    Assignee: China Petrochemical Development Corp
    Inventors: Hsiao Chan Liu, Min Sheng Chen, Chin Yi Lee
  • Patent number: 8580402
    Abstract: A new class of dibenzothiophene and/or dibenzofuran-containing compounds are provided. The new compounds may be useful in organic light emitting devices, particularly as the host of an emissive layer having a host and an emissive dopant, or as a material in an enhancement layer.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: November 12, 2013
    Assignee: Universal Display Corporation
    Inventors: Chun Lin, Alexey Borisovich Dyatkin, Zeinab Elshenawy, Walter Yeager
  • Patent number: 8580398
    Abstract: A material for electroluminescent devices which comprises a compound in which a heterocyclic group having nitrogen is bonded to carbazolyl group and an organic electroluminescent device having at least one organic thin film layer which is sandwiched between the cathode and the anode and contains the above material in at least one layer, are provided. The material can provide organic electroluminescent devices emitting bluish light with a high purity of color. The organic electroluminescence device uses the material.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: November 12, 2013
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Toshihiro Iwakuma, Chishio Hosokawa, Hidetsugu Ikeda, Seiji Tomita, Takashi Arakane
  • Patent number: 8580393
    Abstract: A polymer compound including a repeating unit shown by the following formula (1) wherein at least one of Ar1, Ar2 and Ar3 in the formula (1) is a group shown by the formula (2) and the two bonds shown in the formula (1) are present on any one or any two of Ar1, Ar2, Ar3 and L1.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: November 12, 2013
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Yumiko Mizuki, Nobuhiro Yabunouchi, Mitsuru Eida
  • Patent number: 8580399
    Abstract: Novel compounds containing substituted oligoazacarbazole chains are provided. These compounds are useful in organic light emitting devices, in particular as hosts in the emissive layer of such devices.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: November 12, 2013
    Assignee: Universal Display Corporation
    Inventors: Alexey Dyatkin, Lichang Zeng
  • Patent number: 8563591
    Abstract: the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein X represents C or N; Y represents C or N; L represents a methyl or a direct bond; Z1 represents a direct bond, C1-2alkyl- or a divalent radical of formula —CH2—CH? (a) or —CH? (b); Z2 represents a direct bond, C1-2alkyl- or a divalent radical of formula —CH2—CH? (a) or —CH? (b); R1 represents hydrogen, halo, cyano, amino, phenyl, hydroxy, C1-4alkyloxycarbonyl, hydroxycarbonyl, NR3R4 or C1-4alkyl optionally substituted with one or more substituents selected from hydroxycarbonyl, phenyl, C1-4alkyloxy or NR5R6 or R1 represents C1-4alkyloxy- optionally substituted with one or more substituents selected from hydroxycarbonyl, phenyl, C1-4alkyloxy or NR7R8; R2 represents hydrogen, halo, C1-4alkyl or C1-4alkyloxy-; R3 and R4 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-; R5 and R6 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-; R7 and R8 each in
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: October 22, 2013
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Libuse Jaroskova, Joannes Theodorus Maria Linders, Louis Jozef Elisabeth Van Der Veken, Gustaaf Henri Maria Willemsens
  • Patent number: 8557992
    Abstract: The present invention is directed to heterocyclic fused phenanthrolinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: October 15, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Scott D. Kuduk, Jason W. Skudlarek
  • Publication number: 20130245049
    Abstract: The present invention relates to compounds of formula (A), as further defined herein, having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. The invention further relates to the use of such compounds, optionally combined with one or more other drugs having antiviral activity, for the treatment of animals suffering from viral infections, in particular HIV infection.
    Type: Application
    Filed: November 15, 2011
    Publication date: September 19, 2013
    Applicant: Katholieke Universiteit Leuven
    Inventors: Patrick Chaltin, Frauke Christ, Zeger Debyser, Marc De Maeyer, Arnaud Marchand, Damien Marchand, Arnout Voet
  • Patent number: 8524733
    Abstract: The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: September 3, 2013
    Assignee: Auspex Pharmaceuticals
    Inventors: Thomas G. Gant, Manoucherhr M. Shahbaz
  • Patent number: 8497281
    Abstract: The present invention relates to compounds defined by formula I wherein the variables R1, R2, R3, R4, and m are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11?-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: July 30, 2013
    Assignees: Vitae Pharmaceuticals, Inc., Boehringer Ingelheim International GmbH
    Inventors: Matthias Eckhardt, Stefan Peters, Herbert Nar, Frank Himmelsbach, Linghang Zhuang
  • Patent number: 8487100
    Abstract: The current invention is in the field of molecular biology/pharmacology and provides compounds which modulate the effects of GPR30 as well as the classical estrogen receptors alpha and beta (ER? and ER?). These compounds may function as agonists and/or antagonists of one or more of the disclosed estrogen receptors.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: July 16, 2013
    Assignee: STC.UNM
    Inventors: Eric R Prossnitz, Sergey E Tkatchenko, Chetana M Revankar, Larry A Sklar, Jeffrey B Arterburn, Daniel F Cimino, Tudor I Oprea, Cristian-George Bologa, Bruce S Edwards, Alexandor Kiselyov, Susan M Young
  • Publication number: 20130178459
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Application
    Filed: March 29, 2011
    Publication date: July 11, 2013
    Applicant: Oncotherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • Patent number: RE44831
    Abstract: An organic electroluminescent element including at least an emission layer sandwiched between an anode and a cathode, wherein the emission layer comprises at least a compound represented by Formula (A),
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: April 8, 2014
    Assignee: Konica Minolta Holdings, Inc.
    Inventors: Tatsuo Tanaka, Hideo Taka