Intravascular Patents (Class 600/467)
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Publication number: 20070282197Abstract: The invention relates to an instrument able to be introduced into a body as well as an imaging position fixing system and position fixing method for the instrument. A magnet able to be rotated with a rotation drive is provided in an end section of the instrument. The position of the magnet in the body can be determined on the basis of the strength of a magnetic alternating field created by a rotation of the magnet.Type: ApplicationFiled: May 14, 2007Publication date: December 6, 2007Inventors: Ulrich Bill, Martin Hoheisel
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Patent number: 7288264Abstract: Contact killing antimicrobial articles, devices and formulations are described which kill microorganisms on contact. The articles, devices or formulations contain a non-leaching antimicrobial material which is a unique combination of an organic matrix having biocidal metallic materials non-leachably associated with the matrix. The antimicrobial material may used to form an antimicrobial coating or layer on a surface of the article or device, or may be dispersed in a vehicle or carrier to form a topical antiseptic or disinfectant, or solid shape having contact killing antimicrobial properties. When a microorganism contacts the article, device, or formulation, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it.Type: GrantFiled: July 17, 2000Date of Patent: October 30, 2007Assignee: Surfacine Development Company, L.L.C.Inventors: Samuel P. Sawan, Tadmor Shalon, Sundar Subramanyam, Alexander Yurkovetskiy
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Patent number: 7289842Abstract: The invention relates to a medical investigation and/or treatment system comprising: a catheter system, comprising a catheter (1, 7, 9), with a first sensor (4, 11) of an imaging system for optical coherence tomography with an optical fiber via which the light is directed and is radiated in the area of a catheter tip introduced into an area to be investigated, via which fiber reflection light is directed from an illuminated investigation area to a first image processing unit (22), a second sensor (3, 8, 10) of an intravascular ultrasound imaging system to transmit and receive sound pulses which are fed as an electrical signal to a second image processing unit (23), und at least one display unit (24) for presenting the images of the first and second image processing unit (22, 23).Type: GrantFiled: September 21, 2004Date of Patent: October 30, 2007Assignee: Siemens AktiengesellschaftInventor: Michael Maschke
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Patent number: 7267650Abstract: A guiding catheter system employs a flexible shaft having a preformed bend at a distal end. An ultrasound transducer is mounted proximal to the pre-formed bend. The ultrasound transducer has a field of view directed to a distal tip of the guiding catheter. The guiding catheter includes an open lumen adapted for the introduction of payloads through the catheter system. The guiding catheter system can be used to direct a smaller guiding catheter or guide wire into a destination vessel from a heart chamber. In one application, the guiding catheter system is used to introduce a guiding catheter into the coronary sinus ostium from the right atrium.Type: GrantFiled: December 16, 2002Date of Patent: September 11, 2007Assignee: Cardiac Pacemakers, Inc.Inventors: Mina Chow, William E. Webler
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Patent number: 7226417Abstract: An ultrasound transducer assembly of the present invention includes a flexible circuit to which an ultrasound transducer array and integrated circuitry are attached during fabrication of the ultrasound transducer assembly. The flexible circuit comprises a flexible substrate to which the integrated circuitry and transducer elements are attached while the flexible substrate is in a substantially flat shape. The flexible circuit further comprises electrically conductive lines that are deposited upon the flexible substrate. The electrically conductive lines transport electrical signals between the integrated circuitry and the transducer elements. After assembly, the flexible circuit is re-shapable into a final form such as, for example, a substantially cylindrical shape.Type: GrantFiled: September 13, 1996Date of Patent: June 5, 2007Assignee: Volcano CorporationInventors: Michael J. Eberle, Douglas N. Stephens, Gary Rizzuti, Horst F. Kiepen, Andreas Hodjicostis
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Patent number: 7194297Abstract: Intravascular device for matching impedances of portions of an intravascular circuit and limiting RF signal-induced heating of intravascular conductors. An intravascular device includes alternating conductive and dielectric layers and an electrically conductive coil in a configuration that effects an impedance-matching circuit. Another embodiment of an intravascular device has cylindrical inner and outer walls formed of an expandable, electrically conductive material, the inner and outer walls being separated by a compressible dielectric material. Varying the pressure in the lumen defined by the inner wall changes the spacing between the inner and outer walls, thereby changing the capacitance between the inner and outer wall. Another embodiment of an intravascular device includes one or more coaxial chokes for limiting heating caused by currents induced by RF signals. A conductive shield of the choke is formed of a conductive polymer to further reduce heating effects.Type: GrantFiled: November 13, 2001Date of Patent: March 20, 2007Assignee: Boston Scientific Scimed, Inc.Inventors: Dnyanesh Talpade, Scott R. Smith, Kevin D. Edmunds, Kenneth R. Larson
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Patent number: 7194294Abstract: The present invention provides multi-functional medical catheters, systems and methods for their use. In one particular embodiment, a medical catheter (100) includes a flexible elongate body (105) having a proximal end (110) and a distal end (120). A plurality of spaced apart electrodes (130–136) are operably attached to the flexible body near the distal end. At least some of the electrodes are adapted for mapping a tissue and, in some embodiments, at least one of the electrodes is adapted for ablating a desired portion of the tissue. The catheter includes a plurality of tissue orientation detectors (140–146) disposed between at least some of the electrodes. In this manner, the medical catheter is capable of tissue mapping, tissue imaging, tissue orientation, and/or tissue treatment functions.Type: GrantFiled: May 2, 2003Date of Patent: March 20, 2007Assignee: Scimed Life Systems, Inc.Inventors: Dorin Panescu, David K. Swanson
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Patent number: 7155272Abstract: An ultrasound catheter includes a transducer unit used for observation of the inside of an organism, observation lumens in which the transducer unit is disposed and which extend in the direction of insertion into the organism, a first guide wire lumen provided substantially in parallel to the observation lumens and on the distal end side in the insertion direction in relation to the transducer unit and through which a guide wire preliminarily brought to the inside of the organism is passed, and a second guide wire lumen provided on an extension line of the first guide wire lumen and on the proximal end side in the insertion direction in relation to the transducer unit and through which the guide wire is passed.Type: GrantFiled: September 5, 2003Date of Patent: December 26, 2006Assignees: Terumo Kabushiki Kaisha, Tetsu YamaguchiInventors: Tetsu Yamaguchi, Hiroyuki Yagami, Yasukazu Harada
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Patent number: 7144371Abstract: A transesophageal ultrasound probe for imaging internal structures via an imaging element located on the distal end of a rotating endoscope shaft. The probe includes a rotating endoscope having an imaging element mounted on the distal end of the rotating endoscope shaft. The probe also includes a control handle for controlling the imaging controls and a rotation tube that extends through the rotating endoscope shaft and into the control handle. The rotating shaft rotates relative to, and independently of, the control handle. Preferably, the rotating shaft is rotated via a rotation control wheel. The rotation control wheel is fastened or bonded to the rotating tube so that manual rotation of the control wheel causes the rotation tube to rotate, and therefore, the rotating shaft to rotate. Because the rotating endoscope shaft rotates, an imaging element located on, or within, the rotating shaft also rotates.Type: GrantFiled: March 22, 2004Date of Patent: December 5, 2006Assignee: GE Medical Systems Global Technology Company, LLCInventors: Stephen Dodge Edwardsen, Dag Jordfald
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Patent number: 7131948Abstract: A catheter is provided for insertion in the he blood vessel of a patient for ultrasonically imaging the vessel wall. The catheter includes a tubular element and an internally housed drive cable for effective circumferential scan about the catheter of an ultrasonic generating means. Both the tubular element and the drive cable are of a size and flexibility sufficient to permit their introduction into the vessel and subsequent advancement through the vessel to the location of the vessel wall where imaging is desired.Type: GrantFiled: October 22, 2003Date of Patent: November 7, 2006Assignee: Scimed Life Systems, Inc.Inventor: Paul G. Yock
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Patent number: 7074188Abstract: A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image.Type: GrantFiled: August 25, 2003Date of Patent: July 11, 2006Assignee: The Cleveland Clinic FoundationInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingensmith, Barry D. Kuban
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Patent number: 7052463Abstract: A cooling system for an ultrasonic imaging system is provided, the ultrasonic imaging system having a probe for transmitting and receiving acoustic signals through a tip of the probe to and from biological tissue contacting the tip at an outer surface of the tip. The cooling system includes a conduit for circulating cooling medium therein, and a heat exchanger in fluid communication with the circulating cooling medium and having means for removing heat from the circulating cooling medium, wherein at least a portion the conduit is in proximity to or contacts the outer surface of the probe tip. In a first embodiment the conduit includes an inlet fluid line extending from the heat exchanger to the tip of the probe for providing the circulating cooling medium from the heat exchanger to the probe tip, and an outlet cooling line extending from the tip of the probe to the heat exchanger for providing circulating cooling medium from the probe tip to the heat exchanger.Type: GrantFiled: September 25, 2002Date of Patent: May 30, 2006Assignee: Koninklijke Philips Electronics, N.V.Inventors: Michael Peszynski, John J. Merlo, Matthew Robert Rielly
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Patent number: 7024025Abstract: A new image processing method reduces Nonuniform Rotational Distortion (NURD) in a medical image acquired using a rotating transducer. The image comprises a plurality of image vectors having texture. In a preferred embodiment, the image processing technique computes an average frequency of the texture for each image vector and estimates an angle for each image vector based on the average frequency for the respective image vector. The image processing technique then corrects for NURD by remapping each image vector to the estimated angle for the respective image vector.Type: GrantFiled: February 5, 2002Date of Patent: April 4, 2006Assignee: Scimed Life Systems, Inc.Inventor: Shashidhar Sathyanarayana
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Patent number: 6996432Abstract: An improved medical imaging system preferably includes an imaging device having a housing, an imaging transducer, and a position marker coupled near the imaging transducer. The system further includes a motor capable of driving the imaging transducer in a generally longitudinal direction relative to the housing. Data obtained from tracking the position marker may be cross-correlated with data obtained from the imaging transducer. In one aspect, the position marker may be a sensor capable of communicating with a medical positioning system.Type: GrantFiled: August 11, 2003Date of Patent: February 7, 2006Assignee: SciMed Life Systems, Inc.Inventors: Isaac Ostrovsky, William E. Webler, Mark S. Buhr
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Patent number: 6979293Abstract: A method for monitoring a clot dissolution treatment in a patient's vasculature comprises positioning a catheter at a treatment site in the patient's vasculature. The method further comprises performing a clot dissolution treatment at the treatment site. The clot dissolution treatment comprises delivering ultrasonic energy and a therapeutic compound from the catheter to the treatment site such that a clot located at the treatment site at least partially dissolves. The method further comprises delivering a thermal measurement signal from a first portion of the catheter to the treatment site during the clot dissolution treatment. The method further comprises receiving the thermal measurement signal at a second portion of the catheter. The method further comprises comparing the delivered thermal measurement signal with the received thermal measurement signal to evaluate a blood flow rate at the treatment site.Type: GrantFiled: December 16, 2002Date of Patent: December 27, 2005Assignee: Ekos CorporationInventors: Douglas R. Hansmann, Robert L. Wilcox, Floyd Karp, Natalya Peskin, Kim R. Volz
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Patent number: 6969354Abstract: An intraoperative or endocavity ultrasound probe for insertion into a patient is provided. An adaptable or adjustable section is provided between the handle and the transducer for rotating the transducer relative to the handle prior to insertion within the patient. The adjustable or adaptable section maintains the adjusted or rotated position while the probe is in use within the patient. The adjustable or adaptable section stays in the same pre-bent position, such as by using a memory-less device or material, and is free of user adjustment while the probe is in use.Type: GrantFiled: September 25, 2001Date of Patent: November 29, 2005Assignee: Acuson CorporationInventor: Vaughn R. Marian
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Patent number: 6966891Abstract: A catheter includes a sheath main body portion, a first lumen, a sheath distal end portion, and a second lumen. The sheath main body portion is inserted into an organism. The first lumen is a passage provided in the sheath main body portion and through which a guide wire for guiding the sheath main body portion in an organism can be passed. The sheath distal end portion is provided on a lateral side of a distal end portion of the sheath main body portion. The second lumen is a passage different from the first lumen, provided in the sheath distal end portion, and through which a guide wire can be passed. The catheter can have both ease of exchange of catheter, which is the merit of an RX type catheter, and distal end pushing force transmission performance (pushability), which is the merit of an OTW type catheter.Type: GrantFiled: August 26, 2003Date of Patent: November 22, 2005Assignee: Terumo Kabushiki KaishaInventors: Itaru Ookubo, Hiroyuki Yagami
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Patent number: 6899682Abstract: The present invention comprises methods for fabricating an ultrasound transducer assembly having a flexible circuit. Preferably, the method comprises attaching an ultrasound transducer array and integrated circuitry to the flexible circuit during fabrication of the ultrasound transducer assembly while the flexible circuit is in a substantially flat shape. The contacts of the transducer elements are positioned on substantially the same plane such that electrical contact with signal and ground lines on the flexible circuit is established without the need for conductive bridges to physically remote electrodes.Type: GrantFiled: September 12, 2003Date of Patent: May 31, 2005Assignee: Volcano Therapeutics, Inc.Inventors: Michael J. Eberle, P. Michael Finsterwald
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Publication number: 20040267239Abstract: An intravascular catheter system has a balloon angioplasty device disposed about a common lumen near its distal end. The common lumen is in communication with multiple lumens within a proximal region of the catheter body to allow for positioning of the catheter over a movable guide wire and convenient delivery of imaging or interventional devices to a desired region of the blood vessel being treated.Type: ApplicationFiled: February 13, 2004Publication date: December 30, 2004Applicant: Cardiovascular Imaging Systems, Inc.Inventor: Yue-Teh Jang
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Publication number: 20040254463Abstract: A wave-based tomographic imaging method and apparatus based upon one or more rotating radially outward oriented transmitting and receiving elements have been developed for non-destructive evaluation. At successive angular locations at a fixed radius, a predetermined transmitting element can launch a primary field and one or more predetermined receiving elements can collect the backscattered field in a “pitch/catch” operation. A Hilbert space inverse wave (HSIW) algorithm can construct images of the received scattered energy waves using operating modes chosen for a particular application. Applications include, improved intravascular imaging, bore hole tomography, and non-destructive evaluation (NDE) of parts having existing access holes.Type: ApplicationFiled: March 30, 2004Publication date: December 16, 2004Applicant: The Regents of the University of CaliforniaInventor: Sean K. Lehman
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Publication number: 20040243004Abstract: Apparatus for detecting vulnerable plaques embedded in the wall of a patient's blood vessel includes an intravascular catheter containing a microwave antenna, an extra-corporeal radiometer having a signal input, a reference input and an output, a cable for electrically connecting the antenna to the signal input, and a device for applying an indication of the patient's normal tissue temperature to the reference input so that when the catheter is moved along the vessel, the locations of the vulnerable plaques are reflected in a signal from the output as thermal anomalies due to the higher emissivity of the vulnerable plaques as compared to the normal tissue. A second embodiment of the apparatus has two coaxial antennas in the catheter serving two radiometers. One measures the temperature at locations in the vessel wall, the other measures the temperature at the surface. By subtracting the two signals, the locations of vulnerable plaque may be visualized.Type: ApplicationFiled: June 2, 2003Publication date: December 2, 2004Inventor: Kenneth L. Carr
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Patent number: 6824515Abstract: The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.Type: GrantFiled: November 25, 2002Date of Patent: November 30, 2004Assignee: SciMed Life Systems, Inc.Inventors: Veijo T. Suorsa, David K. Swanson, Dorin Panescu, Harm TenHoff, James G. Whayne
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Publication number: 20040193041Abstract: The present invention is generally directed towards an imaging transducer assembly. Generally, the imaging transducer assembly is combined with a sensor of a medical positioning system. In one aspect, the transducer assembly and the sensor share the same voltage source. In another aspect of the invention, the sensor surrounds a portion of the imaging transducer assembly, forming a housing that reinforces the assembly.Type: ApplicationFiled: March 28, 2003Publication date: September 30, 2004Inventor: Isaac Ostrovsky
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Patent number: 6796945Abstract: An intravascular imaging guidewire is provided that can accomplish longitudinal translation of an imaging plane allowing imaging of an axial length of a region of interest without moving the guidewire. The imaging guidewire comprises a body in the form of a flexible elongate tubular member. An elongate flexible imaging core is slidably received within the body. The imaging core includes a shaft having an imaging device mounted on its distal end. The body and the imaging core are cooperatively constructed to enable axial translation of the imaging core and imaging device relative to the body. The body has a substantially transparent portion extending an axial length over which axially translatable imaging may be performed. The imaging guidewire has a maximum diameter over its entire length sized to be received within a guidewire lumen of an intravascular catheter.Type: GrantFiled: August 8, 2002Date of Patent: September 28, 2004Assignee: SciMed Life Systems, Inc.Inventors: William Martin Belef, Anthony J. Pantages, Lawrence D. Wasicek
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Publication number: 20040176691Abstract: A transesophageal ultrasound probe for imaging internal structures via an imaging element located on the distal end of a rotating endoscope shaft. The probe includes a rotating endoscope having an imaging element mounted on the distal end of the rotating endoscope shaft. The probe also includes a control handle for controlling the imaging controls and a rotation tube that extends through the rotating endoscope shaft and into the control handle. The rotating shaft rotates relative to, and independently of, the control handle. Preferably, the rotating shaft is rotated via a rotation control wheel. The rotation control wheel is fastened or bonded to the rotating tube so that manual rotation of the control wheel causes the rotation tube to rotate, and therefore, the rotating shaft to rotate. Because the rotating endoscope shaft rotates, an imaging element located on, or within, the rotating shaft also rotates.Type: ApplicationFiled: March 22, 2004Publication date: September 9, 2004Inventors: Stephen Dodge Edwardsen, Dag Jordfald
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Publication number: 20040176699Abstract: A flexible thermography catheter which includes an elongated body having a proximal end, a distal end, and a distal section, an expandable body comprising at least one independently movable support arm located at the distal section of the elongated body, at least one support arm retainer positioned on the distal section of the elongated body, and at least one sensor positioned on at least one of the distal section, the expandable body, and the at least one support arm. The at least one support arm retainer is configured to independently secure at least one section of the at least one support arm to the distal section of the elongated body in independently movable relation to each of the at least one support arm and the elongated body.Type: ApplicationFiled: March 3, 2003Publication date: September 9, 2004Applicant: Volcano Therapeutics, Inc.Inventors: Blair Walker, Tracy Maahs, Jesus Flores
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Patent number: 6772001Abstract: A medical examination and/or treatment system has an X-ray image exposure system with a radiation source, a radiation receiver as well as a control and processing device that controls them, a catheter system with a catheter with at least one element in the catheter tip that generates a magnetic field and a device for generating an external magnetic field for guiding the movement of the catheter introduced into a patient by interaction with the magnetic field generated by the element at the catheter tip, as well as an ultrasound image exposure system having a device integrated in the catheter tip for generating and for receiving ultrasound and having a control and processing device that controls this device.Type: GrantFiled: January 17, 2003Date of Patent: August 3, 2004Assignee: Siemens AktiengesellschaftInventor: Michael Maschke
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Patent number: 6755791Abstract: An ultrasonic diagnostic apparatus includes one transmitting coil arranged in the longitudinal direction of an endoscope inserting portion in an ultrasonic endoscope, and another transmitting coil for detecting the position and the direction, which detects the position and the direction of a tomographic plane when forming a tomogram at a distal end portion of an inserting portion by an ultrasonic vibrator. A coil energizing signal is applied to both the transmitting coils so as to generate a magnetic field. The magnetic field is detected by receiving coils. A position and direction calculating circuit detects positional data of the one transmitting coil and positional and directional data of the other transmitting coil. The calculated data is transmitted to an auxiliary-image forming circuit which forms an image of an inserting shape and an auxiliary image indicating the position and the direction of the tomographic plane.Type: GrantFiled: April 17, 2003Date of Patent: June 29, 2004Assignee: Olympus CorporationInventor: Tomonao Kawashima
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Publication number: 20040122325Abstract: A method and apparatus are provided for investigating tissue in which acoustic data are derived from scattering a plurality of pulsed spherical or cylindrical acoustic waves from a plurality of transmission elements through the tissue to a plurality of receiving elements. The acoustic data, which include a mix of reflected and transmitted acoustic waves, are received and digitized, and a representation of a portion of the tissue is generated from the digitized acoustic data.Type: ApplicationFiled: December 18, 2002Publication date: June 24, 2004Applicant: Barbara Ann Karmanos Cancer InstituteInventors: David H. Chambers, Jeffrey Mast, Stephen G. Azevedo, Frank Wuebbeling, Frank Natterer, Nebojsa Duric, Peter J. Littrup, Earle Holsapple
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Publication number: 20040122326Abstract: A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image.Type: ApplicationFiled: August 25, 2003Publication date: June 24, 2004Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingonamith, Barry D. Kuban
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Publication number: 20040116813Abstract: A standardized acquisition methodology assists operators to accurately replicate high resolution B-mode ultrasound images obtained over several spaced-apart examinations utilizing a split-screen display in which the arterial ultrasound image from an earlier examination is displayed on one side of the screen while a real-time “live” ultrasound image from a current examination is displayed next to the earlier image on the opposite side of the screen. By viewing both images, whether simultaneously or alternately, while manually adjusting the ultrasound transducer, an operator is able to bring into view the real-time image that best matches a selected image from the earlier ultrasound examination. Utilizing this methodology, dynamic material properties of arterial structures, such as IMT and diameter, are measured in a standard region over successive image frames.Type: ApplicationFiled: December 13, 2002Publication date: June 17, 2004Inventors: Robert H. Selzer, Howard N. Hodis
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Publication number: 20040116812Abstract: High resolution B-mode ultrasound images of the common carotid artery are obtained with an ultrasound transducer using a standardized methodology. Subjects are supine with the head counter-rotated 45 degrees using a head pillow. The jugular vein and carotid artery are located and positioned in a vertical stacked orientation. The transducer is rotated 90 degrees around the centerline of the transverse image of the stacked structure to obtain a longitudinal image while maintaining the vessels in a stacked position. A computerized methodology assists operators to accurately replicate images obtained over several spaced-apart examinations. The methodology utilizes a split-screen display in which the arterial ultrasound image from an earlier examination is displayed on one side of the screen while a real-time “live” ultrasound image from a current examination is displayed next to the earlier image on the opposite side of the screen.Type: ApplicationFiled: December 13, 2002Publication date: June 17, 2004Inventors: Robert H. Selzer, Howard N. Hodis
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Publication number: 20040087859Abstract: A catheter is provided for insertion in the he blood vessel of a patient for ultrasonically imaging the vessel wall. The catheter includes a tubular element and an internally housed drive cable for effective circumferential scan about the catheter of an ultrasonic generating means. Both the tubular element and the drive cable are of a size and flexibility sufficient to permit their introduction into the vessel and subsequent advancement through the vessel to the location of the vessel wall where imaging is desired.Type: ApplicationFiled: October 22, 2003Publication date: May 6, 2004Inventor: Paul G. Yock
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Patent number: 6716166Abstract: Apparatus for mapping a surface of a cavity within a body of a subject includes an elongate probe, having a longitudinal axis and including a distal portion adapted for insertion into the cavity. A plurality of acoustic transducers are distributed along the longitudinal axis over the distal portion of the probe, which transducers are adapted to be actuated individually to emit acoustic waves while the probe is in the cavity, and are further adapted to receive the acoustic waves after reflection of the waves from the surface of the cavity and to generate, responsive to the received waves, electrical signals indicative of times of flight of the waves.Type: GrantFiled: July 10, 2001Date of Patent: April 6, 2004Assignee: Biosense, Inc.Inventor: Assaf Govari
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Patent number: 6712767Abstract: An ultrasound catheter suitable for insertion in the body lumens of a patient during medical procedures is provided. An ultrasound transducer may be provided at the distal tip of the catheter. An inflatable balloon may be provided at the distal end of the catheter on the proximal side of the ultrasound transducer. The catheter may have lumens for inflation fluid, electrical wires, and a guide wire. A sheath that runs through the balloon may be used to isolate the electrical wires and guide wire from inflation fluid in the interior of the balloon.Type: GrantFiled: August 29, 2002Date of Patent: March 30, 2004Assignee: Volcano Therapeutics, Inc.Inventors: Norman Hugh Hossack, Andrew Thomas Jeffrey, Elvin Leonard Nix
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Patent number: 6712783Abstract: An intravascular catheter system has a balloon angioplasty device disposed about a common lumen near its distal end. The common lumen is in communication with multiple lumens within a proximal region of the catheter body to allow for positioning of the catheter over a movable guide wire and convenient delivery of imaging or interventional devices to a desired region of the blood vessel being treated.Type: GrantFiled: February 7, 2001Date of Patent: March 30, 2004Assignee: Cardiovascular Imaging, Inc.Inventor: Yue-Teh Jang
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Patent number: 6705997Abstract: In order to arrange continuous wave signal paths using fewer switches, a plurality of amplifying circuits 602 for respectively amplifying a plurality of continuous wave input signals, and outputting each respective pair of amplified signals that have mutually opposite phases for each continuous wave input signal; a plurality of selecting circuits 604, each of which selects one signal of the pair of amplified signals from each of the plurality of amplifying circuits; and a matrix switch 608 employing the output signals from the plurality of selecting circuits as input signals are provided.Type: GrantFiled: March 14, 2002Date of Patent: March 16, 2004Assignee: GE Medical Systems Global Technology Company, LLCInventor: Shinichi Amemiya
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Publication number: 20040049148Abstract: An ultrasound catheter adapted for accessing small vessels in the distal anatomy is disclosed. The ultrasound catheter comprises an elongate tubular body formed with a delivery lumen. The flexibility and dimensions of the tubular body allow access to the distal anatomy by advancement over the guidewire. An ultrasound radiating member is provided along the distal end portion of the tubular body for emitting ultrasound energy at a treatment site. A drug solution may also be delivered through the delivery lumen and out an exit port to the treatment site.Type: ApplicationFiled: December 3, 2002Publication date: March 11, 2004Inventors: Oscar Rodriguez, Curtis Genstler, Tim Abrahamson, Wm. Gerrit Barrere, Frederick J. Bennett, George Keilman, Richard R. Wilson, Perry Todd Thompson
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Patent number: 6702750Abstract: The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, both having a proximal end, a distal end, and a lumen therebetween. The inner tubular member is sealed at its distal end and is nested substantially coaxially within the lumen of the outer tubular member, so that the gap between the inner and the outer tubular member defines a second lumen whereas the first lumen is the lumen of the inner tubular member. A tubular sleeve is disposed coaxially between the inner and outer tubular members. A balloon is mounted on a distal region of the outer tubular member and is in communication with the first lumen. The cannula further comprises a port proximal or distal the balloon occluder and is in communication with the second lumen. Methods for making the devices herein are disclosed.Type: GrantFiled: April 14, 2001Date of Patent: March 9, 2004Assignee: Cardiovascular Imaging Systems, Inc.Inventor: Paul G. Yock
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Publication number: 20040039286Abstract: A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer.Type: ApplicationFiled: August 25, 2003Publication date: February 26, 2004Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Barry D. Kuban, Jon D. Klingenamith, D. Geoffrey Vince, Anuja Nair
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Patent number: 6685648Abstract: A method is provided for delivering a drug to a selected tissue region within a patient's body with a catheter having a deployable puncturing element, a drug delivery element and an orientation element on a distal portion thereof. The distal portion of the catheter is percutaneously introduced into a blood vessel, and directed endovascularly to a vessel location adjacent to the selected tissue region. The puncturing element is oriented towards the selected tissue region, and deployed to access the selected tissue region. A drug is delivered with the drug delivery element to the selected tissue region.Type: GrantFiled: April 3, 2001Date of Patent: February 3, 2004Assignee: Transvascular, Inc.Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. MacAulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane
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Publication number: 20040015065Abstract: The present invention provides multi-functional medical catheters, systems and methods for their use. In one particular embodiment, a medical catheter (100) includes a flexible elongate body (105) having a proximal end (110) and a distal end (120). A plurality of spaced apart electrodes (130-136) are operably attached to the flexible body near the distal end. At least some of the electrodes are adapted for mapping a tissue and, in some embodiments, at least one of the electrodes is adapted for ablating a desired portion of the tissue. The catheter includes a plurality of tissue orientation detectors (140-146) disposed between at least some of the electrodes. In this manner, the medical catheter is capable of tissue mapping, tissue imaging, tissue orientation, and/or tissue treatment functions.Type: ApplicationFiled: May 2, 2003Publication date: January 22, 2004Applicant: SCIMED Life Systems, Inc.Inventors: Dorin Panescu, David K. Swanson
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Patent number: 6659950Abstract: A percutaneous epicardial injection apparatus for myocardial repair and treatment includes a catheter having a tubular wall, an interior portion surrounded by the tubular wall, a base end, a distal end, and a central longitudinal axis extending between the catheter base end and the catheter distal end. The catheter distal end has an end face that is formed at an oblique angle relative to the catheter longitudinal axis and adapted to attach to a patient's myocardium using suction. A lumen extends from the catheter base end to the catheter distal end within the catheter interior. The lumen is adapted to slidably support an elongated syringe having a needle tip adapted for movement between a retracted position wherein the needle tip is recessed within the catheter interior to an extended position wherein the needle tip extends from the catheter interior.Type: GrantFiled: April 12, 2001Date of Patent: December 9, 2003Inventor: Syde Taheri
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Patent number: 6660024Abstract: A catheter device that is useable to penetrate from a blood vessel in which the catheter device is positioned to a target location comprises a flexible catheter advanceable into the first blood vessel, a tissue penetrator lumen adapted to receive an operative tissue penetrator which is usable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter including an imaging transducer fixedly mounted on or within the catheter body to provide an imaging signal from which an image of the target location can be obtained. The catheter device may include an imageable marker on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator exits from the catheter. Alternatively, or addition thereto, the imaging transducer may comprise a plurality of imaging elements which are located so that the penetrator path indication can be obtained.Type: GrantFiled: December 26, 2001Date of Patent: December 9, 2003Assignee: TransVascular, Inc.Inventors: J. Christopher Flaherty, Jason B. Whitt, John Y. Chang, David R. Tholfsen, Philip C. Evard, Joshua Makower
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Patent number: 6659957Abstract: The present invention is a guide wire imaging device for vascular or non-vascular imaging utilizing optic acoustical methods, which device has a profile of less than 1 mm in diameter. The ultrasound imaging device of the invention comprises a single mode optical fiber with at least one Bragg grating (8), and a piezoelectric or piezo-ceramic jacket (31), which device may achieve omnidirectional (360°) imaging. The imaging guide wire of the invention can function as the guide wire for vascular interventions, can enable real time imaging during balloon inflation, and stent deployment, thus will provide clinical information that is not available when catheter based imaging systems are used. The device of the invention may enable shortened total procedure times, including the fluoroscopy time, will also reduce radiation exposure to the patient, and the operator.Type: GrantFiled: June 11, 2002Date of Patent: December 9, 2003Inventors: Gil M. Vardi, Victor Spivak
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Patent number: 6645152Abstract: An apparatus for the intravascular placement of a vena cava filter includes a flexible deployment sheath and an IVUC with an ultrasonic imaging element. These two components are joined together and oriented in a substantially parallel relationship with one another with the imaging components of the IVUC extending above or in front of the upper opening of the deployment sheath. Once the apparatus is appropriately positioned within the vena cava, as determined through ultrasonic imaging, a filter and its associated delivery system are inserted through the deployment sheath to the appropriate location for deployment.Type: GrantFiled: August 12, 2002Date of Patent: November 11, 2003Inventors: Matthew T. Jung, Hermann W. Kaebnick, Edward V. Kinney, Richard A. Mitchell
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Patent number: 6635054Abstract: A collapsible ultrasonic reflector incorporates a gas-filled reflector balloon, a liquid-filled structural balloon an ultrasonic transducer disposed within the structural balloon. Acoustic energy emitted by the transducer is reflected by a highly reflective interface between the balloons. In a cardiac ablation procedure, the ultrasonic energy is focused into an annular focal region to ablate cardiac tissue extending in an annular path along the wall. Devices for stabilizing the balloon structure and for facilitating collapse and withdrawal of the balloon structure are also disclosed.Type: GrantFiled: July 13, 2001Date of Patent: October 21, 2003Assignee: Transurgical, Inc.Inventors: Todd Fjield, Edward Paul Harhen, David E. Acker, Patrick David Lopath
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Publication number: 20030191392Abstract: A guiding catheter includes a Doppler sensor disposed at a distal end of a flexible shaft. The Doppler sensor can sense a blood flow turbulence level within a chamber of the heart or a blood vessel of the heart. Detecting changes in a blood flow turbulence level is used to assist guiding of the distal end of the flexible shaft. The Doppler sensor may include a piezoelectric sensor or an optical sensor. The sensor readings may be processed to show turbulence through a time domain or frequency domain presentation of velocity. The sensor readings can be used to modulate an audible waveform to indicate turbulence. The guiding catheter may further include steering apparatus enabling deflection of the distal tip.Type: ApplicationFiled: April 5, 2002Publication date: October 9, 2003Inventor: Paul Craig Haldeman
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Patent number: 6623433Abstract: A longitudinal position translator includes a probe drive module and a linear translation module. The probe drive module is coupled operatively to an ultrasonic imaging probe assembly having a distally located ultrasound transducer subassembly in such a manner that longitudinal shifting of the transducer subassembly may be effected. The probe drive module is preferably mounted to the linear translation unit so as to be moveable between a condition whereby longitudinal shifting of the transducer subassembly can be conducted either manually or automatically. When in the automatically-operable condition, the probe drive module will be engaged with a motor-driven screw associated with the linear translation module so as to cause the probe drive module to be longitudinally displaced at a constant motor-driven rate.Type: GrantFiled: May 3, 2002Date of Patent: September 23, 2003Assignee: SciMed Life Systems, Inc.Inventors: William E. Webler, Mark S. Buhr
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Publication number: 20030171667Abstract: A parametric imaging ultrasound catheter apparatus is capable of obtaining parametric images of the surrounding insonated environment. Parametric imaging is defined as the imaging of quantifiable “parameters” which of visible two-, three-, fourth-dimensional or non-visible higher-dimensional temporal physiologic events. Visible motion is a fourth-dimensional event and includes surrogate features of cardiac muscle contraction, wall motion, valve leaflet motion, etc. Non-visible motion is a higher-dimensional event and includes slow non-visible events (i.e., remodeling, transformation, aging, healing, etc.) or fast non-visible events (i.e., heat, electricity, strain, compliance, perfusion, etc.). An ultrasound catheter with parametric imaging capability can obtain dynamic digital or digitized information from the surrounding environment and display information features or quanta as a static or dynamic geometric figures from which discrete or gross quantifiable information can be obtained.Type: ApplicationFiled: January 24, 2003Publication date: September 11, 2003Inventor: James B. Seward