Abstract: A catheter and method for determining a position of the catheter within the cardiovascular system is provided. Local bending and twisting is measured at multiple locations along the catheter. By integrating the measurements, the position and orientation of the catheter is determined. Based on the catheter position information, the location and orientation of an ultrasound transducer array connected with the catheter is known. The imaging array position and orientation information may be used to assist a physician in determining the tissue structure or fluid being scanned and/or assist in the accurate generation of three-dimensional representations.

Abstract: The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.

Abstract: The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, both having a proximal end, a distal end, and a lumen therebetween. The inner tubular member is sealed at its distal end and is nested substantially coaxially within the lumen of the outer tubular member, so that the gap between the inner and the outer tubular member defines a second lumen whereas the first lumen is the lumen of the inner tubular member. A tubular sleeve is disposed coaxially between the inner and outer tubular members. A balloon is mounted on a distal region of the outer tubular member and is in communication with the first lumen. The cannula further comprises a port proximal or distal the balloon occluder and is in communication with the second lumen. Methods for making the devices herein are disclosed.

Abstract: A parametric imaging ultrasound catheter apparatus is capable of obtaining parametric images of the surrounding insonated environment. Parametric imaging is defined as the imaging of quantifiable “parameters” which of visible two-, three-, fourth-dimensional or non-visible higher-dimensional temporal physiologic events. Visible motion is a fourth-dimensional event and includes surrogate features of cardiac muscle contraction, wall motion, valve leaflet motion, etc. Non-visible motion is a higher-dimensional event and includes slow non-visible events (i.e., remodeling, transformation, aging, healing, etc.) or fast non-visible events (i.e., heat, electricity, strain, compliance, perfusion, etc.). An ultrasound catheter with parametric imaging capability can obtain dynamic digital or digitized information from the surrounding environment and display information features or quanta as a static or dynamic geometric figures from which discrete or gross quantifiable information can be obtained.

Abstract: An ultrasonic angioplasty device includes a catheter and a connector assembly for interconnecting an ultrasound transmission member to an ultrasound transducer. A rotation control device is provided that prevents the ultrasound transmission member from rotating relative to the catheter. Rotation is prevented by a fastener aligning the connector assembly with the elongated catheter body, or a key member that fits in a correspondingly shaped slot in a proximal shaft portion of the catheter, for preventing rotation of the connector assembly relative to the catheter.

Abstract: The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.

Abstract: Methods and apparatus for blood speckle detection for enhanced intravascular ultrasound imaging. The present invention utilizes the fact that the energy scattering strength from blood exhibits a high frequency dependency, while the scattering strength from tissue lacks a strong frequency dependency. In specific embodiments, the present invention may provide a particularly simple and useful solution for addressing the problem of blood speckle in intravascular ultrasound imaging, especially in situations where the blood may have a scattering strength similar to that of tissue and/or where the blood is moving slowly or not at all.

Abstract: A catheter assembly includes an elongate catheter body having a proximal end and a distal end with a drive cable disposed therein, the drive cable having a proximal end and a distal end, and rotatable relative to the catheter body. A first electro-magnetic element is disposed proximate the distal end of the catheter, and a second electro-magnetic element disposed proximate the distal end of the drive cable and in electrical communication with an operative element mounted at the end of the drive cable, the first and second electro-magnetic elements forming an inductive coupler. The catheter assembly can include various other distal operative elements, which are in communication with corresponding proximal operative elements via transmission lines embedded within the wall of the catheter body.

Abstract: An apparatus and method for determining angular position of a sensor within a catheter. The invention is particularly useful for imaging devices delivered to a body lumen by a catheter, as may be the case for IVUS imaging catheters. The apparatus consists of a catheter having an inner core with an imaging sensor disposed within an inner diameter of a sheath of the catheter. The sheath is also provided with an outer diameter which has a center which it does not share with a center of the inner diameter. As a result, the catheter has a wall of non-uniform thickness. The imaging sensor is able to determine its position within its imaging rotation due to the non-uniform thickness. This positioning characteristic helps eliminate any Non-Uniform Rotational Distortion (NURD), which would otherwise result in undesired and unpredictable compressed and expanded images of vasculature sought to be imaged.

Abstract: An apparatus and method for the intravascular placement of a vena cava filter includes an outer sheath, an intravascular ultrasound catheter with an ultrasonic imaging element, a guide wire, and the vena cava filter that is to be deployed. The outer sheath, ultrasound catheter, and guide wire share a common central axis. The ultrasound catheter is enclosed by and is moveable relative to the outer sheath, and the guide wire is enclosed by and is moveable relative to the ultrasound catheter. In the stored position, the filter is secured between the outer sheath and the ultrasound catheter. When the apparatus is introduced into a vein, the ultrasound catheter provides real-time imaging of the vein for identifying the appropriate location for placement of the filter. Once such a location has been identified, the outer sheath is drawn back relative to the ultrasound catheter, exposing the legs of the filter, allowing the legs of the filter to spring free and attach themselves to the wall of the vein.

Abstract: A radiation delivery system including a catheter shaft having a distal head. A fixed or removable radiation source is disposed adjacent the distal head. The distal head includes a radiation shield having a window and an ultrasonic transducer. The ultrasonic transducer provides a signal indicative of relative position, tissue geometry and/or tissue characteristics, which may be utilized to determine the appropriate placement of the radiation shield window such that only selected portions of the treatment site are exposed to radiation. The radiation delivery system may include a drive means coupled to the distal head to facilitate rotation thereof. The rotatable head may be rotated at a constant velocity or at a velocity which varies as a function of the signal (e.g., distance from the vascular wall and/or stenotic thickness).

Abstract: The invention relates to a method and a device for determining the position of a medical instrument (3) that is introduced into an object (1) to be examined and for imaging the vicinity of the medical instrument (3).

Abstract: A parametric imaging ultrasound catheter apparatus is capable of obtaining parametric images of the surrounding insonated environment. Parametric imaging is defined as the imaging of quantifiable “parameters” which of visible two-, three-, fourth-dimensional or non-visible higher-dimensional temporal physiologic events. Visible motion is a fourth-dimensional event and includes surrogate features of cardiac muscle contraction, wall motion, valve leaflet motion, etc. Non-visible motion is a higher-dimensional event and includes slow non-visible events (i.e., remodeling, transformation, aging, healing, etc.) or fast non-visible events (i.e., heat, electricity, strain, compliance, perfusion, etc.). An ultrasound catheter with parametric imaging capability can obtain dynamic digital or digitized information from the surrounding environment and display information features or quanta as a static or dynamic geometric figures from which discrete or gross quantifiable information can be obtained.

Abstract: A method for mapping a heart comprises the steps of inserting a mapping catheter having an ultrasonic position sensor into the heart. At least one reference catheter having an ultrasonic position sensor is also inserted into the heart. The position of the mapping catheter is determined relative to the at least one reference catheter and a portion of the heart is mapped with the mapping catheter. Additionally, the at least one reference catheter may be provided outside of the heart.

Abstract: A system for mapping a heart comprises a mapping catheter having an ultrasonic position sensor for insertion into the heart. The system also comprises at least one reference catheter having an ultrasonic position sensor placeable in a fixed position relative to the heart. The position of the mapping catheter is determined relative to the at least one reference catheter. The ultrasonic position sensor of the mapping catheter is located at the tip of the mapping catheter. The ultrasonic position sensor for the at least one reference catheter is located at the tip of the at least one reference catheter.

Abstract: A vascular catheter system comprises a catheter body having a proximal and distal portion and a single common lumen therebetween. The catheter body includes a first connector secured to the distal end of the proximal portion and a second connector secured to the proximal end of the distal portion. The connectors can be selectively connected to each other to join the lumens of the proximal and distal portions together in a continuous, axially fixed relationship. Disposed within the lumens, when the proximal and distal portions are joined together, is a drive cable. The drive cable may be movably, rotatable about its own longitudinal axis and carries at its distal end, a work element, which is typically an ultrasonic imaging transducer or interventional device. The lumen carrying the cable will be sufficiently large along a proximal portion to permit preferential collapse of the cable should rotation of the distal end become impeded.

Abstract: A local and site-specific drug delivery apparatus for delivering a drug to a specific site is characterized by the combination of a carrier material which reflects or absorbs or emits electromagnetic or mechanical (e.g. ultrasonic) vibrations enabling the monitoring of the material, a drug associated with the carrier material, and a local-delivery mechanism for delivering the carrier material and the drug to a specific site. The local-delivery mechanism may comprise a local-delivery catheter, such as a balloon-type catheter, and the drug delivery apparatus may additionally include a monitor for monitoring the delivery of the drug to the specific site, such as an ultrasonic imaging system. The drug delivery apparatus may also include a vibration generator for inducing release of the drug from the carrier material when the carrier material is at the specific site, such as a generator of ultrasonic energy.

Abstract: The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, both having a proximal end, a distal end, and a lumen therebetween. The inner tubular member is sealed at its distal end and is nested substantially coaxially within the lumen of the outer tubular member, so that the gap between the inner and the outer tubular member defines a second lumen whereas the first lumen is the lumen of the inner tubular member. A tubular sleeve is disposed coaxially between the inner and outer tubular members. A balloon is mounted on a distal region of the outer tubular member and is in communication with the first lumen. The cannula further comprises a port proximal or distal the balloon occluder and is in communication with the second lumen. Methods for making the devices herein are disclosed.

Abstract: An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.

Abstract: The present invention provides ultrasound imaging catheters, systems and methods for their use which will be particularly useful to monitor the positioning of ablation catheters. In one embodiment, an imaging catheter (10) includes a catheter body (11) having a distal end (12), a proximal end (14) and a longitudinal axis (16). A transducer (20) is rotatably coupled to the distal end. The transducer has an axis of rotation (24) that is at a non-zero angle relative to the catheter body longitudinal axis. Such a configuration provides an exemplary side-looking imaging catheter.

Abstract: An underfluid ultrasound imaging catheter system includes a catheter having a distal end inserted into an underfluid structure, an ultrasonic transducer array mounted proximate the distal end of the catheter wherein the array has a row of individual transducer crystals, a lens mounted on the array for defocusing ultrasound beams in a direction perpendicular to an axis of the array so as to provide a volumetric field of view within which the underfluid features are imaged. Alternatively, the single row of transducer crystals is replaced by multiple rows of transducer crystals so as to provide a volumetric field of view. This imaging catheter system helps an operator see 3-dimensional images of an underfluid environment, such as the 3-dimensional images of fluid-filled cavities of heart, blood vessel, urinary bladder, etc. Features in such wide volumetric field of view can be imaged, measured, or intervened by an underfluid therapeutic device with an aid of the real-time image.

Abstract: A catheter is provided for insertion in the he blood vessel of a patient for ultrasonically imaging the vessel wall. The catheter includes a tubular element and an internally housed drive cable for effective circumferential scan about the catheter of an ultrasonic generating means. Both the tubular element and the drive cable are of a size and flexibility sufficient to permit their introduction into the vessel and subsequent advancement through the vessel to the location of the vessel wall where imaging is desired.

Abstract: According to the invention, an object in an ultrasound image is characterized by considering various in-vivo object parameters and their variability within the ultrasonic imaging data. Specifically, it is assumed that the object may be defined in terms of statistical properties (or object identifying parameters), which are consistently different from properties of the environment. Such properties are referred to as the object's signature. The statistical properties are calculated at selected locations within the image to determine if they fall within a predetermined range of values which represents the object. If within the range, the locations are marked to indicate they are positioned within the object. A border may then be drawn around the object and the area calculated.

Abstract: A catheter is provided that has both an ultrasonic transducer array (2) and a inflatable balloon (12) mounted at or near its distal end. A sheath catheter having a transducer array and associated multiplexer (4) arrangement located substantially coaxially within it. Furthermore, a guidewire (8) catheter having an ultrasonic transducer array mounted on it distal end.

Abstract: An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuit of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.

Abstract: A system and method for the prevention of restenosis uses a source of radiation to treat the blood vessel. An intra-vascular ultrasound system acquires precise two-dimensional images of a treatment volume. The intra-vascular ultrasound system enables medical personnel to obtain precise measurements of the distance between the radiation source and the lesion. Whereas conventional techniques for measuring this distance relied upon external imaging devices, the intra-vascular ultrasound system obtains in-vivo images allowing precise measurements to be taken at the point at which the radiation will be delivered. A computer-based treatment planner acquires the images from the imaging system and reconstructs a three-dimensional image of the treatment volume. From a dose prescription, the treatment planner calculates and optimizes the dose and also registers the dose with images of the treatment volume. A voice recognition unit allows medical personnel to provide voice commands for operating the system.

Abstract: An acoustic therapy apparatus has a source of therapeutic acoustic waves and an ultrasound locating means with an ultrasound transducer, wherein the source and the ultrasound transducer are combined to form an oblong applicator with a longitudinal axis provided for introduction into the body interior of a patient, the ultrasound locating system generating ultrasound images with respect to a plane that contains the longitudinal axis of the applicator. The source and the ultrasound transducer are disposed relative to each other in the applicator so that the source and the ultrasound transducer are successively arranged in the direction of the longitudinal axis, with the ultrasound transducer being arranged preceding the source the in introduction direction, and the center axis of the plane describing an angle of less than 90° with that section of the longitudinal axis of the applicator located in the region of the source so that the center axis is inclined toward the source.

Abstract: Methods and apparatus for blood speckle detection for enhanced intravascular ultrasound imaging. The present invention utilizes the fact that the energy scattering strength from blood exhibits a high frequency dependency, while the scattering strength from tissue lacks a strong frequency dependency. In specific embodiments, the present invention may provide a particularly simple and useful solution for addressing the problem of blood speckle in intravascular ultrasound imaging, especially in situations where the blood may have a scattering strength similar to that of tissue and/or where the blood is moving slowly or not at all.

Abstract: In a method of manufacturing an ultrasonic transducer array a plurality of discrete transducer elements are formed on an initially flat flexible substrate together with electrically conductive tracks, through which the transducer elements will be energised in use, the flexible substrate with the discrete transducer elements and conductive tracks mounted thereon then being formed into a cylinder and mounted on the end of a catheter tube, the substrate being radially outwardly of the transducer elements so that it is in a position to act also as an acoustic matching layer between the material of the transducer elements and the human tissues or blood when in use.

Abstract: The preferred embodiments include a diagnostic medical ultrasound system and method for object of interest extraction. Unlike some extraction techniques, the preferred embodiments do not require the user to perform the time consuming task of manually tracing the border of the object of interest. Further, unlike some automatic border detection techniques, the preferred embodiments produce an accurate border of an object of interest even if the object of interest is connected to neighboring anatomy with similar properties.

Abstract: The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.

Abstract: A method and system for characterizing plaque components within a vascular object is provided. The vascular object is scanned with an ultrasonic device and backscatter signal data is collected. Histology images are prepared and digitized which correspond to the scanned vascular sections. A plaque component is selected on the histology image and its coordinates are mapped to a corresponding location on an IVUS image constructed from the backscatter signal. The IVUS image location is then translated to the corresponding signal section of the raw backscatter signal. Frequency analysis is performed on the signal section to determine its signal properties. The signal properties are correlated to the selected plaque component of the histology image and stored in a plaque characterization database. The process is then repeated for all plaque components and other tissue types found within the vascular object and stored in the database.

Abstract: Guide catheter incorporating a braidless construction having increased performance characteristics for catheterization procedures. The guide catheter may include a tracking wire, inner or outer guide for positioning the guide catheter within the patient's vascular system.

Abstract: A self-contained ultrasound catheter device capable of delivering diagnostic and therapeutic tools in a field of ultrasound includes a rotatable multiplane sector phased array imaging ultrasound transducer used for the visualization of under fluid structures and/or diagnostic and therapeutic events. The multiplane sector phased array is rotatable around an axis of an ultrasound beam to obtain sequential imaging planes in a continuous or interrupted sweep up to 360 degrees. The transducer being a multiplane transducer allows more versatile visualization of underfluid structures and/or events. The sequential acquisition of tomographic images is suitable for 3-dimensional image reconstruction.

Abstract: In an ultrasonic imaging system, a transducer array structure, preferably a linear one-dimensional array on a catheter, is provided wherein the direction of a beam is controlled by a preselected, linear delay profile implementing a linear portion of a beam forming equation so that the array is effectively curved electronically. Beam forming is effected independently of the steering. An active aperture is provided by which a beam is steered according to linear array techniques. The active aperture comprises selected adjacent subsets of transducer elements of the array structure. The delay profile may be implemented by delay lines to each transducer element or by any preselected delay elements whereby the flatness or curvature of the array structure is matched and so that beam steering can be implemented by simple translation of the aperture along the transducer array. The pitch or separation between the transducer elements may be uniform or varied.

Abstract: A device and method for intravascular ultrasound imaging. A catheter including ultrasonic apparatus is introduced into and may be moved through a bodily lumen. The apparatus transmits ultrasonic signals and detects reflected ultrasound signals which contain information relating to the bodily lumen. A processor coupled to the catheter is programmed to derive a first image or series of images and a second image or series of images from the detected ultrasound signals. The processor is also programmed to compare the second image or series of images to the first image or series of images respectively. The processor may be programmed to stabilize the second image in relation to the first image and to limit drift. The processor may also be programmed to monitor the first and second images for cardiovascular periodicity, image quality, temporal change and vasomotion. It can also match the first series of images and the second series of images.

Abstract: Three-dimensional reconstructions of tortuous vessels such as coronary arteries can be obtained by data fusion between biplane angiography and IVUS frames of a pullback sequence. The 3D course of the tortuous vessel is first determined from the angiograms and then combined with the 2D representations regarding the 3D course (e.g., segmented IVUS frames of a pullback sequence) using a data fusion apparatus and method: The determination of the 3D pullback path is represented by the external energy of the tortuous vessel and the internal energy of a line object such as a catheter.

Abstract: An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.

Abstract: Methods and apparatus for non-uniform rotation distortion detection for enhanced intravascular ultrasound imaging. The present invention provides methods and apparatus which detect non-uniform rotation in an improved manner without using beacons which may create shadowing of tissue behind the beacons or other undesired artifacts in the image. In specific embodiments, the present invention may provide a particularly simple and useful solution for addressing the problem of non-uniform rotation distortion in intravascular ultrasound imaging in systems which use mechanical scanning. In specific embodiments, the present invention utilizes correlation of received signals in an image vector from reverberating ultrasound in a bubbly liquid-flushed catheter to determine non-uniform rotation of the transducer within the catheter.

Abstract: An ultrasound transducer having an acoustic backing layer made of an aerogel material is disclosed. The ultrasound transducer comprises an acoustic element for transmitting and receiving ultrasound waves. An aerogel acoustic backing layer is bonded to the back side of the acoustic element. A matching layer may be attached to the front side of the acoustic element. The ultrasound transducer may be electrically connected using electrodes directly connected to the acoustic element. Alternatively, the aerogel acoustic backing may be coated with a metalized layer or doped so that it is electrically conductive. Then, the electrodes may be connected directly to the aerogel acoustic backing.

Abstract: An underfluid ultrasound imaging catheter system includes a catheter having a distal end inserted into an underfluid structure, an ultrasonic transducer array mounted proximate the distal end of the catheter wherein the array has a row of individual transducer crystals, a lens mounted on the array for defocusing ultrasound beams in a direction perpendicular to an axis of the array so as to provide a volumetric field of view within which the underfluid features are imaged. Alternatively, the single row of transducer crystals is replaced by multiple rows of transducer crystals so as to provide a volumetric field of view. This imaging catheter system helps an operator see 3-dimensional images of an underfluid environment, such as the 3-dimensional images of fluid-filled cavities of heart, blood vessel, urinary bladder, etc. Features in such wide volumetric field of view can be imaged, measured, or intervened by an underfluid therapeutic device with an aid of the real-time image.

Abstract: A device and method for intravascular ultrasound imaging. A catheter including ultrasonic apparatus is introduced into and may be moved through a bodily lumen. The apparatus transmits ultrasonic signals and detects reflected ultrasound signals which contain information relating to the bodily lumen. A processor coupled to the catheter is programmed to derive a first image or series of images and a second image or series of images from the detected ultrasound signals. The processor is also programmed to compare the second image or series of images to the first image or series of images respectively. The processor may be programmed to stabilize the second image in relation to the first image and to limit drift. The processor may also be programmed to monitor the first and second images for cardiovascular periodicity, image quality, temporal change and vasomotion. It can also match the first series of images and the second series of images.

Abstract: Systems and related methods guide a movable electrode within an array of multiple electrodes located within the body. The systems and methods employ the movable electrode or at least one of the multiple electrodes on the array to generate and then sense electrical or sonic energy in a predetermined fashion to generates an output that locates the movable electrode within the array.

Abstract: A real time three dimensional ultrasound imaging probe apparatus is configured to be placed inside a body. The apparatus comprises an elongated body having proximal and distal ends with an ultrasonic transducer phased array connected to and positioned on the distal end of the elongated body. The ultrasonic transducer phased array is positioned to emit and receive ultrasonic energy for volumetric forward scanning from the distal end of the elongated body. The ultrasonic transducer phased array includes a plurality of sites occupied by ultrasonic transducer elements. At least one ultrasonic transducer element is absent from at least one of the sites, thereby defining an interstitial site. A tool is positioned at the interstitial site. In particular, the tool can be a fiber optic lead, a suction tool, a guide wire, an electrophysiological electrode, or an ablation electrode. Related systems are also discussed.

Abstract: Methods and apparatus for blood speckle detection for enhanced intravascular ultrasound imaging. The present invention utilizes the fact that the energy scattering strength from blood exhibits a high frequency dependency, while the scattering strength from tissue lacks a strong frequency dependency. In specific embodiments, the present invention may provide a particularly simple and useful solution for addressing the problem of blood speckle in intravascular ultrasound imaging, especially in situations where the blood may have a scattering strength similar to that of tissue and/or where the blood is moving slowly or not at all.

Abstract: A vascular catheter system comprises a catheter body having a proximal and distal portion and a single common lumen therebetween. The catheter body includes a first connector secured to the distal end of the proximal portion and a second connector secured to the proximal end of the distal portion. The connectors can be selectively connected to each other to join the lumens of the proximal and distal portions together in a continuous, axially fixed relationship. Disposed within the lumens, when the proximal and distal portions are joined together, is a drive cable. The drive cable may be movably, rotatable about its own longitudinal axis and carries at its distal end, a work element, which is typically an ultrasonic imaging transducer or interventional device. The lumen carrying the cable will be sufficiently large along a proximal portion to permit preferential collapse of the cable should rotation of the distal end become impeded.

Abstract: An underfluid ultrasound imaging catheter system includes a catheter having a distal end inserted into an underfluid structure, an ultrasonic transducer array mounted proximate the distal end of the catheter wherein the array has a row of individual transducer crystals, a lens mounted on the array for defocusing ultrasound beams in a direction perpendicular to an axis of the array so as to provide a volumetric field of view within which the underfluid features are imaged. Alternatively, the single row of transducer crystals is replaced by multiple rows of transducer crystals so as to provide a volumetric field of view. This imaging catheter system helps an operator see 3-dimensional images of an underfluid environment, such as the 3-dimensional images of fluid-filled cavities of heart, blood vessel, urinary bladder, etc. Features in such wide volumetric field of view can be imaged, measured, or intervened by an underfluid therapeutic device with an aid of the real-time image.

Abstract: A transducer assembly having an improved external connection configuration, a method for manufacturing such a transducer assembly, and a catheter system incorporating the transducer assembly. The improved connection configuration is achieved by creating a conductive path from an upper electrode of the transducer to an electrically conductive notch surface formed on an edge of the transducer assembly so that an external electrical lead can be attached to the active portion of the transducer element via the path.

Abstract: A transducer assembly having an improved external connection configuration, a method for manufacturing such a transducer assembly, and a catheter system incorporating the transducer assembly. The improved connection configuration is achieved by creating a conductive path from an upper electrode of the transducer to an upper surface of the transducer assembly so that an external electrical lead can be attached to the active portion of the transducer element via the path.

Abstract: An ultrasound system is disclosed having a catheter including an elongate flexible catheter body having at least one lumen extending longitudinally therethrough. The catheter further includes an ultrasound transmission member extending longitudinally through the lumen of the catheter body, the ultrasound transmission member having a proximal end connectable to an ultrasound transducer. The catheter also includes a distal head positioned on the distal end of the ultrasound transmission member. The catheter also has a coil with a proximal end connected to the distal end of the catheter body, and a distal end connected to the distal head. The coil defines a lumen communicating with the lumen of the catheter body. The ultrasound system also includes a sonic connector for coupling the ultrasound transmission member to the transducer. Different configurations are disclosed for the distal head and the ultrasound transmission member.