Material Conduit Forced Into Body By Spring Patents (Class 604/136)
  • Patent number: 11311240
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: April 26, 2022
    Assignee: DexCom, Inc.
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Patent number: 11285266
    Abstract: A drug delivery device includes a reservoir, a drug delivery member in fluid communication with the reservoir, and a plunger disposed in and moveable relative to the reservoir. A plunger rod has a mass MP and is movable from (i) a first position, where the distal end of the plunger rod is spaced apart from the plunger to (ii) a second position, where the distal end of the plunger rod contacts the plunger. A drive mechanism is coupled to the proximal end of the plunger rod and is configured to deliver a drive force FD to move the plunger rod from the first position to the second position. A ratio of the mass of the plunger rod to the drive force of the drive mechanism (MP/FD) is in a range of approximately a value greater than 0 kg/kgf to approximately 0.05 kg/kgf.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: March 29, 2022
    Assignee: AMGEN INC.
    Inventors: Sean Fitzgibbon, Julian Jazayeri
  • Patent number: 11285260
    Abstract: A button safety cap for a patch pump or other fluid infusion device prevents accidental activation of an activation button of a catheter insertion device. The button safety cap includes a stabilizing surface adapted to stabilize the patch pump when the patch pump is oriented for filling a reservoir port.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: March 29, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Russell Cole
  • Patent number: 11276327
    Abstract: The present disclosure relates to an administration mechanism (9) for a medicament delivery training device.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: March 15, 2022
    Assignee: SHL MEDICAL AG
    Inventor: Anders Boström
  • Patent number: 11266777
    Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: March 8, 2022
    Assignee: AMGEN INC.
    Inventors: Scott R. Gibson, Sheldon B. Moberg, Basel Hasan Taha, Margaux Frances Boyaval, Mark A. Destefano, John C. Love, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente, Rajan Ramaswamy, Daniel S. Codd, Scott Beaver, Kevin L. Bokelman, Sean M. O'connor, Robert Decker, Gautam N. Shetty, Ryan M. Agard, Nicholas J. Ciccarelli, Daniel Davenport
  • Patent number: 11266783
    Abstract: An injection device for the self-administration of an injection of solution that includes a body portion/handle configured for engagement with a cartridge containing the solution and an injection needle. The injection device includes a safety mechanism whereby ejection of solution from the injection device cannot be done unless the safety mechanism is released. The injection device further involves two-stage deployment whereby a needle may be inserted upon release of the safety mechanism and solution is injected upon full insertion of the needle.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: March 8, 2022
    Assignee: DJ Medical, LLC
    Inventors: Daniel Schneider, Troy A. Pongratz
  • Patent number: 11270604
    Abstract: In an embodiment, a resettable shield-activated injection training device is provided. The training device includes an outer housing comprising a proximal end and a distal end, an inner housing comprising a proximal end and a distal end, plunger retention protrusions near the proximal end, and an asymmetrical projection at the distal end.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: March 8, 2022
    Assignee: NOBLE INTERNATIONAL, INC.
    Inventors: Jeff Baker, Wai Yin Christopher Chung, Shishuang Hou, Francis Michael Siemer
  • Patent number: 11266782
    Abstract: The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support comprises a projecting portion, which projects from the syringe support in a distal direction and a flexible portion which axially adjoins the projecting portion. The flexible portion is adapted to axially bias the syringe (in the distal direction within the housing. The disclosure further relates to an autoinjector.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: March 8, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Thomas Mark Kemp, Louise Hodgson
  • Patent number: 11253201
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 22, 2022
    Assignee: DexCom, Inc.
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Patent number: 11241539
    Abstract: An injection device, method, and system for drug delivery includes a container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug; an injection drive mechanism having a plunger for acting on the stopper and an energy source having a first selected potential energy for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug; and a plunger loading mechanism for substantially preventing the plunger from accelerating to a predetermined velocity before it acts on the stopper. The plunger loading mechanism may be a spring having a second selected potential energy for reducing or eliminating a distance between the plunger and the stopper, prior to the plunger accelerating to the velocity. The second selected potential energy of the spring may be less than the first selected potential energy of the energy source.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: February 8, 2022
    Assignee: AMGEN INC.
    Inventors: Christopher R. Folk, Scott R. Gibson, Brian J. Intoccia
  • Patent number: 11224696
    Abstract: An injector for delivering medicament includes a first sleeve defining a longitudinal axis, a medicament container, and a locking tab. The medicament container is at least partially disposed within the first sleeve and configured for axial translation with respect to the first sleeve along the longitudinal axis. The medicament container includes a barrel, a needle mounted to a distal end of the barrel, a seal slidably mounted in the barrel, and a plunger rod. The locking tab extends through an aperture in the first sleeve and is in contact with or adjacent to a portion of the medicament container such that the locking tab restricts translation of the barrel with respect to the first sleeve along the longitudinal axis. The locking tab is configured to be movable to a second position in which the locking tab does not restrict translation of the barrel.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: January 18, 2022
    Assignee: Action Medical Technologies, LLC
    Inventor: Thor Rollings Halseth
  • Patent number: 11197689
    Abstract: An inserter (100) for subcutaneous insertion of multiple transcutaneous parts (212, 222), the multiple transcutaneous parts at least comprising: —a first transcutaneous part (212) comprising a first body (214) from where a first subcutaneous part (216) extends, and—a second transcutaneous part (222) comprising a second body (224) from where a second subcutaneous part (226) extends, wherein the inserter comprises: —support means for guiding the multiple transcutaneous parts during insertion of the multiple transcutaneous parts, and—activation means for activating the inserter, whereby simultaneously insertion of the multiple transcutaneous parts subcutaneously in the patient's skin is initiated.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: December 14, 2021
    Assignee: UNOMEDICAL A/S
    Inventor: Steffen Gyrn
  • Patent number: 11191908
    Abstract: An injection device, for example, an auto-injector of any type, includes a sleeve configured to hold a medicament chamber. The sleeve may be sufficiently deformable such that it functions as a shock absorbing member to distribute the force exerted on the medicament chamber during use of the injection device.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: December 7, 2021
    Assignee: Antares Pharma, Inc.
    Inventors: John Pierre Mehawej, Michael Travanty
  • Patent number: 11141084
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: October 12, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Jeffery V. Funderburk, Duane O. Yamasaki, Brian VanHiel, Stephen J. Flynn, Bradley D. Kelemen
  • Patent number: 11141534
    Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: October 12, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
  • Patent number: 11116911
    Abstract: A device that prevents the accidental activation and lockout of an autoinjector. In illustrative embodiments, a resistance unit is configured to resist deployment of the needle until a critical force is applied by the user to the autoinjector, at which point, the resistance of the resistance unit is overcome. Continuous application of force by the user after the resistance is overcome drives the delivery device to the injection site where the medication is administered.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: September 14, 2021
    Assignee: BIOGEN MA, INC.
    Inventor: Haiming Wu
  • Patent number: 11103680
    Abstract: Manual insertion device has retraction spring (202) and hollow septum configuration (224) implemented using barrel-shaped guides (108, 110) and a guiding boss (210) in insertion device housing (106), and provides a fluid path through alignment of septum openings, side-port openings and catheter openings upon complete catheter insertion. Button (200) causes manual insertion of introducer needle (204) and catheter (220) of a first barrel (108) into a skin surface, and loading of retraction spring (202) disposed in an adjacent second barrel (110). Once introducer needle (204) and catheter (220) are fully inserted, the introducer needle hub (206) is released and automatically retracted by release of the retraction spring (202), leaving the catheter (220) in the user's body. Septums (218, 224) and side-port openings (216, 228) in the button (200) and introducer needle (204) are thus aligned, creating an uninterrupted fluid path between a reservoir or pump and catheter (220).
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: August 31, 2021
    Assignee: Becton, Dickinson and Company
    Inventor: Russell Cole
  • Patent number: 11083840
    Abstract: Modular fluid path assemblies are provided that include conduit, coupling, and needle portions of a fluid path fluidly coupled to an outlet of a container. The modular fluid path assemblies further include a needle shield having a tip of the needle embedded therein. So configured, in embodiments, the modular fluid path assemblies can be sterilized, a medicament can be filled in the container, and a stopper inserted in the container so that the pre-sterilized and pre-filled modular fluid path assemblies can have a closed container integrity (CCI) seal.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: August 10, 2021
    Assignee: AMGEN INC.
    Inventors: Scott Robert Gibson, Sudeshna Dutta Ray, Daniel Eduardo Groszmann, Mehran Mojarrad, Nathan Thomas Balcom, Alejandro Campillo-Agusti, Alan D. Payne, Lawrence Scott Ring
  • Patent number: 11045603
    Abstract: Systems for piercing a septum of a drug delivery device is disclosed. The drug delivery device may include a needle conduit having an end and a drug container having a septum. The septum piercing mechanism may include a needle support operatively coupled to the needle conduit. The septum piercing mechanism may be movable from a first, unactivated configuration to a second, activated configuration. In the unactivated configuration, the septum seals an interior of the drug container from the end of the needle conduit. In the activated configuration, the end of the needle conduit pierces through the septum placing the needle conduit in fluid communication with the drug container. In one embodiment, activation may cause the needle support to move towards the drug container. In one embodiment, the needle support may be moved by a biasing member. Alternatively, in another embodiment, the needle support may be moved by a cam mechanism.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: June 29, 2021
    Assignee: INSULET CORPORATION
    Inventors: Maureen McCaffrey, Ian McLaughlin
  • Patent number: 10980938
    Abstract: A device and method for creating a fluid path are disclosed. A patch pump may include a start button. A force may be applied on a button needle in a force direction, based on activating the start button. A first end of the button needle may puncture a fluid container by moving the button needle from a first button needle position to a second button needle position via the force in the force direction. A second end of the button needle may be positioned underneath a carrier septum contained in a carrier, via the applied force. The carrier may be released based on activating the start button and the second end of the button needle, based on releasing the carrier, may puncture the carrier septum. A fluid path may be provided form the fluid container to a patient's tissue based on puncturing the fluid container and the carrier septum.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: April 20, 2021
    Assignee: FLEX LTD.
    Inventors: Eyal Barmaimon, Lior Shtram, Shai Finkman, Itay Landsman
  • Patent number: 10933193
    Abstract: An injection device is presented having a housing, a container holder, a first and a second energy accumulating member arranged in the interior of the housing adapted to accumulate and store energy, a sleeve, a plunger holder operationally associated with said first energy accumulating member such that the plunger holder and the container holder are axially moveable in relation to the housing a predetermined distance towards the proximal end of the injection device from an initial position to a position following needle penetration, and a plunger rod being operationally associated with said second energy accumulating member such that the plunger rod is axially moveable in relation to the container holder, wherein in the initial position movement of the plunger holder is substantially inhibited by at least one first biasable member that recoils when being overlapped by an opening and/or recess of the sleeve such that the plunger holder is released.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: March 2, 2021
    Assignee: SHL MEDICAL AG
    Inventors: Anders Boström, Elin Gabrielsson
  • Patent number: 10918846
    Abstract: To achieve stable administration of a medicine into a dermis by improving the operability of a device that inserts a microneedle into a skin. An impacting type applicator (1) for a microneedle patch is an applicator that applies a microneedle patch (3) to a skin includes a main body (5), a spring expanding/compressing lever (7), a resilient body (9), a lock mechanism (11), and a piercing switch (13). The spring expanding/compressing lever (7) is movably attached to the main body (5), and the microneedle patch (3) can be attached to a leading end of the spring expanding/compressing lever (7). The resilient body (9) is a member that imparts a biasing force to the spring expanding/compressing lever (7). The lock mechanism (11) is a mechanism that locks the spring expanding/compressing lever (7) in a state where the resilient body (9) exerts the biasing force on the main body (5).
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: February 16, 2021
    Assignee: Labo Juversa Co., Ltd.
    Inventors: Hiroyuki Nagai, Risa Nakaoka, Ichiro Ono, Kanji Takada
  • Patent number: 10918803
    Abstract: A syringe carrier includes a housing adapted to receive a syringe having a needle encapsulated by a removable protective needle sheath, and two or more flexible arms protruding inwards in a relaxed state and adapted to couple with the syringe in a mounted position. The flexible arms are adapted to deflect radially outwards in a pre-assembled position of the syringe in the syringe carrier. In the mounted position the flexible arms are allowed to return into the relaxed state due, in part, to an axial force operating on the syringe carrier. The disclosure further relates to an autoinjector and a method of assembling the autoinjector.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: February 16, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Thomas Mark Kemp, William Timmis, Louise Hodgson
  • Patent number: 10905829
    Abstract: A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.
    Type: Grant
    Filed: November 3, 2014
    Date of Patent: February 2, 2021
    Assignee: CONSORT MEDICAL PLC
    Inventors: Alastair Willoughby, Marta Vilaplana, Alan Judd
  • Patent number: 10898646
    Abstract: According to aspects of the present disclosure, a retaining apparatus for use with a medicament delivery device is provided. The medicament delivery device includes a container holder assembly and an actuator assembly. The container holder assembly is configured to receive a container containing a medicament. The container holder assembly is configured to couple to the actuator assembly. The actuator assembly includes a plunger rod for engaging a stopper in the container. The retaining apparatus includes a plunger lock, a retaining member, and a biasing member. The plunger lock is seated within a proximal end of the actuator assembly, and secures the plunger rod. The retaining member is seated within the plunger lock. The biasing member is secured between the proximal end of the actuator assembly and the retaining member. The retaining member is biased in a proximal direction by the biasing member.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: January 26, 2021
    Assignee: SHL Medical AG
    Inventors: Per Klintenstedt, Anders Wieselblad, Gunnar Elmen
  • Patent number: 10881795
    Abstract: An auto-injector for hypodermic delivery of medication includes a first subassembly releasably coupled to a second subassembly. The first subassembly includes a cartridge holder configured to receive a medication cartridge, an injection needle through which medication can pass from the medication cartridge, and a needle shield movable between an extended position enclosing the needle and a retracted position in which a proximal end of the needle is not enclosed by the needle shield. The second subassembly includes a movable plunger rod positioned within a housing. Movement of the needle shield in a proximal direction from the retracted position to the extended position following administration of the medication automatically releases the first subassembly from the second subassembly. The released first subassembly is locked with the needle shield in the extended position. A new first subassembly containing an unused dosage of medication may be inserted and releasably connected to the second subassembly.
    Type: Grant
    Filed: January 20, 2018
    Date of Patent: January 5, 2021
    Assignee: L.G.P. TECHNOLOGY HOLDINGS LLC
    Inventor: Lucio Giambattista
  • Patent number: 10881796
    Abstract: An automatic injection device is provided herein comprising a container body having a distal end and a proximal end; a piston locked at said proximal end of said container body before medication injection; a spring configured to bias said piston distally; a releasable restraining means configured to releasably restrain said piston in a locked state against said biasing of said spring, wherein, upon release of said releasable restraining means, said piston moves under force of said spring toward said distal end of said container body; an activation means configured to release said releasable means; a needle cap placed at said distal end of said container body; and a needle placed at said distal end of said container body.
    Type: Grant
    Filed: March 7, 2015
    Date of Patent: January 5, 2021
    Inventor: Min Wei
  • Patent number: 10881804
    Abstract: The present invention relates to a medicament delivery device comprising a housing, which housing is arranged to accommodate a medicament container, a drive unit operably arranged to act on said medicament container for expelling a dose of medicament, the drive unit comprising a plunger rod, a force element operably connected to said plunger rod, a connector arranged to releasibly hold said plunger rod, an actuator element operably arranged to said connector and a manually operable actuator arranged to act on said actuator element for releasing said connector when operated. The invention is characterised in a safety device arranged to releasibly hold said actuator element in a locking position with said connector, preventing unintended release of said plunger rod.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: January 5, 2021
    Assignee: SHL MEDICAL AG
    Inventors: Stefan Lööf, Stefan Morén
  • Patent number: 10814066
    Abstract: Medication dispensing apparatuses for dosing-up and delivering a pre-set dosage of a fluid product include a housing; a dosing element moveable relative to the housing between a starting position and a dosed-up position; a drive system coupled to the dosing element operable to initiate or perform a dispensing operation; and a sub-dose preventing system for preventing or blocking a dispensing operation of the drive system when the dosing element has not reached the dosed-up position and for allowing or unblocking a dispensing operation of the drive system when or after the dosing element has reached the dosed-up position, wherein the sub-dose preventing system is operable to block a rotational movement in a circumferential direction of the medication dispensing apparatus of a drive element of the drive system corresponding to a dispensing direction or a dial-down direction when preventing or blocking the dispensing operation of the drive system.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: October 27, 2020
    Assignee: Ypsomed AG
    Inventors: Ulrich Moser, Christian Schrul, Jürg Hirschel
  • Patent number: 10799644
    Abstract: The invention relates to a medical injection device having a polymeric housing or housing parts. The housing comprises a moulded outer housing element and a moulded elongated tubular inner housing element. The elongated tubular inner housing element is formed as one unitary element and carries a pointer and one or more projections in predetermined and correlated positions. The pointer points to indicia on a scale drum and the projections engage the scale drum. The outer housing element is moulded over the elongated tubular inner housing element in a 2K moulding to form one single housing component.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: October 13, 2020
    Assignee: Novo Nordisk A/S
    Inventors: Ken Hansen, Imran Ghulam, Jesper Bach Noergaard, Claus Urup Gjoedesen, Asger Meng Larsen
  • Patent number: 10780222
    Abstract: This disclosure teaches the concept, and method of creating, a dual use device intended for persons who take insulin. In one embodiment, the novel device is an insulin delivery cannula, the outer wall of which contains electrodes, chemical compounds and electrical interconnects that allow continuous glucose sensing and delivery of data to a remote device. Heretofore, the main problem in attempting to sense glucose at the site of insulin delivery has been the high current resulting from oxidation by the sensor of the preservatives in the insulin formulations. One means of eliminating these interferences is to poise the indicating electrode(s) of the sensor at a bias sufficiently low to avoid the signal from oxidation of the preservatives. One way of obtaining a glucose signal at a low bias is to use an osmium-ligand-polymer complex instead of conventional hydrogen peroxide sensing.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: September 22, 2020
    Assignee: PACIFIC DIABETES TECHNOLOGIES INC
    Inventors: William Kenneth Ward, Robert S Cargill, Gabriel Heinrich, Sheila Benware, Mark Vreeke, Joseph D. Kowalski, Thomas Seidl
  • Patent number: 10773023
    Abstract: The present invention relates to a medicament delivery device comprising a housing having opposite distal and proximal ends; a medicament container holder with a medicament container, disposed within the housing, wherein the container has a front opening with or for a delivery member for delivering the medicament therethrough and at least a movable stopper; a drive unit comprising a power source and a plunger rod, wherein said drive unit is arranged to be movable between a non-delivery state in which said power source is in a cocked state and a delivery state in which said power source acts on said plunger rod which in its turn acts on said stopper for delivering a dose of medicament from said medicament container; retaining means operably connected to said drive unit, and capable of holding said drive unit in its non-delivery state; and activation means operably connected to said retaining means, and capable of releasing said drive unit from its non-delivery state; wherein the device further comprises a deli
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: September 15, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Lucio Giambattista, Antonio Bendek
  • Patent number: 10758677
    Abstract: The present invention relates to a drive mechanism for a medicament delivery device, comprising a plunger rod (54) arranged to act on a stopper (28) arranged in a medicament container (16); a compression drive spring (58) operably connected to said plunger rod (54) and capable of applying a force on said plunger rod (54); a spring guide (78) arranged coaxial with, and radially outside, said compression drive spring (58), capable of preventing buckling of said drive spring, wherein said spring guide (78) comprises a resilient force element (86) capable of applying a force on said medicament container (16).
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: September 1, 2020
    Assignee: SHL MEDICAL AG
    Inventor: Brian Maxfield
  • Patent number: 10729853
    Abstract: According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: August 4, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Yannick Hourmand, Timothy Donald Barrow-Williams, Matthew Ekman
  • Patent number: 10716893
    Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: July 21, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Eric Yeaton
  • Patent number: 10709844
    Abstract: A safety member for use with an injection device is disclosed. The safety member includes a blocking ring extending into a housing of the injection device in blocking association with a latch member associated with a trigger mechanism of the injector, in which the blocking ring blocks movement of a portion of the trigger mechanism into a firing position. The safety member further includes a manipulable portion disposed outside the housing and configured for hand-manipulation by a user to remove the safety member from the housing to unblock the firing mechanism to enable firing of the injector.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: July 14, 2020
    Assignee: Antares Pharma, Inc.
    Inventors: Julius C. Sund, Eric Lagman, Peter A. Hoeft, Paul R. Lesch, Jr., Thomas E. Kramer
  • Patent number: 10660823
    Abstract: An assembly for mixing drug components includes a housing to at least partially hold a first drug component container and a second drug component container. The assembly also includes a transfer member having first and second ends to fluidly couple the respective first and second drug component containers. The assembly further includes a pressure member to fluidly couple the first drug component container to a pressure generation chamber. In addition, the assembly includes an energy storage member to generate pressure in the pressure generation chamber to transfer a fluid from the first drug component container into the second drug component container. Moreover, the assembly includes an exit member to fluidly couple the second drug component container to an exterior of the assembly.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: May 26, 2020
    Assignee: CREDENCE MEDSYSTEMS, INC.
    Inventors: Alan E. Shluzas, Stephen H. Diaz
  • Patent number: 10653849
    Abstract: Medicament delivery device comprising a movable guard (10) being movable between a proximal and a distal position and a locking mechanism (15) having a lever (16), the lever (16) restricting movement of an actuation locking member (24) until the movable guard is positioned in a distal position and the lever (16) restricting movement of the guard (10) in a proximal position after actuation of the device.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: May 19, 2020
    Assignee: SHL Group AB
    Inventor: Anders Holmqvist
  • Patent number: 10646662
    Abstract: An injection device that comprises a chamber configured for containing a substance to be injected and a needle operatively associated with the chamber and having a length sufficient to deliver the substance to an intradermal injection site. A collar surrounds the needle, defining a collar cavity. The collar also has a peripheral forward skin-contacting surface that surrounds and is radially spaced from the needle and injection site by an area that is sufficiently large to allow a patient's skin to move into the collar cavity to properly position the needle for intradermal delivery of the substance to the injection site to allow spread of the injected substance under the skin while inhibiting or preventing backpressure within the skin from forcing the substance out through the injection site.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: May 12, 2020
    Assignee: Antares Pharma, Inc.
    Inventors: Peter L. Sadowski, Paul R. Lesch, David L. Bremseth
  • Patent number: 10632259
    Abstract: A medicament delivery device includes a holding unit (5), a driving unit (7) releasably held by the holding unit, an activation unit (6) used to release the driving unit from the holding unit, and an injection unit (8) to be moved by the driving unit. The injection unit includes a hub (85) held by the driving unit, a cannula (86) fixed to the hub and a container (83) slidably connected to the hub. After the driving unit is released, the proximal end of the cannula protrudes out of the activation unit before the distal end of the cannula fluidly communicates with the container. The medicament delivery device is combined with an electronic device in an assembly. When a casing cap of the assembly is removed, the electronic device or an app in the electronic device or a function of the electronic device is automatically activated to wirelessly communicate with another electronic device.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: April 28, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Daniel Scott, Slobodan Stefanov, Chun Chu
  • Patent number: 10625023
    Abstract: An auto-injector device including a syringe, a needle arranged in the vicinity of a first end of the syringe, and a plunger arranged within the syringe. A volume within the syringe between the plunger the needle accommodates medicine, such that movement of the plunger toward the needle dispenses medicine through the needle. A selection assembly configurable by a user to adjust an amount of medicine dispensed by the auto-injector device and depth to which the medicine is delivered. Also, a method for treating a skin lesion or skin disorder utilizing the auto-injector and a kit for patient administered treatment.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: April 21, 2020
    Inventor: Joseph Onorato
  • Patent number: 10603446
    Abstract: Catheter and needle assemblies with spring-powered retractable needles are described. The assemblies can include a hollow handle, a grip portion, a catheter hub with a catheter, and a needle. The needle can have a first position in which the needle is slidably disposed within the catheter and a second position in which the needle is slidably removed from the catheter and retracted at least in part into the hollow handle. The grip portion can include a trigger portion that activates a spring to move the needle from the first position into the second position. In the second position, a sharp distal point of the needle is shielded by the grip portion to prevent accidental needle sticks.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: March 31, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Stephanie J Branson, Weston F Harding, S Ray Isaacson
  • Patent number: 10576206
    Abstract: An apparatus includes a housing, a carrier, and an expandable assembly. The housing defines an opening configured to selectively place a gas chamber of the housing in fluid communication with an exterior volume. The carrier is movably disposed within the housing and is coupled to a medicament container. A proximal surface of the carrier defines a portion of a boundary of the gas chamber. The expandable assembly has a first member and a second member. The first member is coupled to an elastomeric member disposed within the medicament container, and the second member includes a valve portion. The expandable assembly transitions from a collapsed configuration to an expanded configuration when the elastomeric member moves within the medicament container. The valve portion moves relative to the opening when the expandable assembly transitions from the first to the second configuration, placing the gas chamber in fluid communication with the exterior volume.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: March 3, 2020
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Paul F. Meyers
  • Patent number: 10556065
    Abstract: An injection pen comprises a circularly pushing device (1) and a vial housing (2), and is used to combine a medication vial (3) with a needle (4). The circularly pushing device (1) comprises a jointing member (10), a spiral sleeve (20), a spiral duct (30), a spirally-pushing tube (40), a threaded-connection shrink-ring (50), a propelling lever (60), a one-way ratchet ring (70), and an injection operation member (80). During the injection, the one-way ratchet ring (70) on a push rod (81) is jointed with a one-way ratchet groove portion (46) of the spirally-pushing tube (40) so as to restrain the rotation directions of the push rod (81) and the spirally-pushing tube (40); the propelling lever (60) cannot be rotated due to the limit of the jointing member (10).
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: February 11, 2020
    Assignee: CC Biotechnology Corporation
    Inventor: Chin-Min Yeh
  • Patent number: 10543310
    Abstract: The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. The flow activator may be actuated in a deployment direction by a deployment actuator, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, an effector may enable fluid communication between the opening and the vacuum source and may do so in response to actuation of the flow activator.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: January 28, 2020
    Assignee: Seventh Sense Biosystems, Inc.
    Inventors: Howard Bernstein, Donald E. Chickering, III, Ping Gong, Shawn Davis
  • Patent number: 10529252
    Abstract: In an embodiment, a resettable shield-activated injection training device is provided. The training device includes an outer housing comprising a proximal end and a distal end, an inner housing comprising a proximal end and a distal end, plunger retention protrusions near the proximal end, and an asymmetrical projection at the distal end.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: January 7, 2020
    Assignee: Noble International, Inc.
    Inventors: Jeff Baker, Wai Yin Christopher Chung, Hou Shi Shuang, Francis Michael Siemer
  • Patent number: 10512733
    Abstract: According to the invention a safety device for a pre-filled syringe comprises a substantially cylindrical and hollow support body and a hollow needle shield slideably arranged relative to the support body. The support body comprises at least one resilient arm and the hollow needle shield or a needle shield assembly comprises at least one curved actuation ramp. The curved actuation ramp protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device. The curved actuation ramp comprises a first lateral dimension (L1) at a proximal end of the needle shield and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield. The resilient arm engages the curved actuation ramp when the needle shield is slid relative to the support body.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: December 24, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Gareth Roberts, Chris Ward, Matthew Ekman
  • Patent number: 10426895
    Abstract: The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device and to such a drug delivery device. The mechanism comprises a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member in a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member in a decoupled state, and a spring biasing the clutch into its coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: October 1, 2019
    Assignee: Sanofi
    Inventors: William Marsh, Anthony Paul Morris, Joseph Butler, Matthew Jones, Samuel Steel, Richard James Vincent Avery
  • Patent number: 10420899
    Abstract: An assembly for a drug delivery device (200) is provided, the assembly comprising a needle mounting feature (1), a needle detector (2), a housing (3) and a movable feature (4) which is movably connected to the housing (3) and movable with respect thereto between a first position and a second position different from the first position. The needle detector (2) is configured to detect whether a needle (101) is mounted to the needle mounting feature (1). The assembly is further configured such that when a needle (101) is mounted to the needle mounting feature (1), the movable feature (4) is in the second position and when the needle (101) is not mounted to the needle mounting feature (1), the movable feature (4) is in the first position.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: September 24, 2019
    Assignee: Sanofi
    Inventors: Paul Richard Draper, Michael Bainton, Matthew Jones
  • Patent number: 10413660
    Abstract: An infusion set is disclosed that includes an inserter including an inserter housing having at least one flexible arm for holding an infusion set in a single axial position prior to insertion of at least a portion of a cannula of the infusion set, the inserter housing having a surface for contacting the patient's skin. The inserter also includes a movable plunger disposed within the inserter housing for releasing the infusion set from the inserter housing, impacting the infusion set, and imparting momentum to the infusion set to insert the cannula into the patient's skin. The inserter additionally includes a biasing element biasing the plunger toward the activated position.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: September 17, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Eric Bene, Russell Cole, Arthur Klotz, Melissa Rosen, Judy Lin Walish, Michel Bruehwiler, Michael Creighton