Abstract: An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.

Abstract: An apparatus includes a housing, a medicament container and an actuator. The actuator includes a release member and an energy storage member having a first position and a second position. In the first position, the energy storage member has a first potential energy. In the second position the energy storage member has a second potential energy. The energy storage member is configured to convert a portion of the first potential energy into kinetic energy when moved from the first position to the second position to move the medicament container within the housing. The energy storage member has a longitudinal axis offset from a longitudinal axis of the medicament container. The release member is configured to selectively deploy the energy storage member from its first position to its second position.

Abstract: An injection device comprising an outer housing inside which is located a medicament-holding barrel (9) with a needle (10) at one end thereof, at least part of the needle being moveable in and out of the outer housing, a plunger (8) moveable within the barrel, an inner housing (7) intermediate the outer housing (6) and the barrel and plunger and an energy source (1) in communication with said inner housing. The inner housing is moveable by the energy source between a first position in which the plunger and barrel are movable axially so as to move at least part of said needle out of the outer housing; a second position in which the plunger is movable axially into said barrel so as to expel medicament through the needle; and a third position in which the plunger and barrel are able to retract in order to retract the needle into the outer housing.

Abstract: An injection device comprising an outer housing inside which is located a medicament-holding barrel with a needle at one end thereof, at least part of the needle being moveable in and out of the outer housing, a plunger moveable within the barrel, an inner housing intermediate the outer housing and the barrel and plunger and an energy source in communication with said inner housing. The inner housing is moveable by the energy source between a first position in which the plunger and barrel are movable axially so as to move at least part of said needle out of the outer housing; a second position in which the plunger is movable axially into said barrel so as to expel medicament through the needle; and a third position in which the plunger and barrel are able to retract in order to retract the needle into the outer housing.

Abstract: An autoinjector including a housing, a receptacle for an active substance, which receptacle, together with a connected injection needle, is displaceable within the housing by spring force for inserting the injection needle into a patient, a piston displaceable within the receptacle by spring force for expelling the active substance, a transfer mechanism for transferring the spring force to the receptacle and/or to the piston, a holding mechanism for holding the transfer mechanism, a releasing mechanism for causing the holding mechanism to release the transfer mechanism when the releasing mechanism is moved from a first position into a second position, and a resetting mechanism for moving the releasing mechanism from the first position into the second position without during the move causing the transfer mechanism to be released.

Abstract: A method of administering liquid medicine such as epinephrine to a patient includes administering a first dose followed by administering an optional second dose is described herein. Also described herein are devices useful for carrying out the methods described and kits containing these devices.

Abstract: An auto-injector confines all functional components inside an enclosed housing, to keep its needle out-of-sight, at all times. Within the housing, a needle holder positions a needle at a location. A drive mechanism then simultaneously engages the needle with a fluid source and accelerates it with a predetermined momentum for insertion into a patient. After fluid delivery, the withdrawn needle is moved to storage within the housing for subsequent disposal.

Abstract: In a device (1) for automatically injecting injection liquids, including an axially subdivided housing whose parts are connectable with each other, wherein an axially displaceable pressure pin (5) is guided in a first housing part (2), which pin is capable of being inserted against a force accumulator (6) and locked in the inserted position and extended upon relief of the force accumulator (6), wherein an injection needle (15) fixed in a needle guide (14) and an ampoule (13) are mounted in a second housing part (3) so as to be axially displaceable relative to each other, wherein the injection needle (15) on its side facing the ampoule (13) is designed as a perforation piece (32) for the ampoule (13), the ampoule (13) with its end facing the injection needle (15) is mounted to reach into a sleeve (16) fixed within the second housing part (3) and whose inner diameter substantially corresponds to the outer diameter of the ampoule (13).

Abstract: An insertion device for applying an infusion set to the body of a patient, wherein the device has two actuation members which have to be actuated simultaneously to trigger an insertion movement by which a cannula of the infusion set is introduced into the body and wherein, in some embodiments, one of the actuation members is a securing slide including a contact face to be placed on the body of the patient, the securing slide being actuated by the insertion device being pressed, via the contact face, against the body of the patient.

Abstract: The suggested device comprises a dispensing piston that is actuatable by a pressure medium for dispensing a syringe and a guide portion within which the dispensing piston is displaceably supported. The device is designed for dispensing a double syringe and includes a handling portion for receiving the pressure medium, the dispensing piston, and the guide portion, as well as locking means that are releasable by applying manual pressure to the handling portion and are arranged on the handling portion and operatively connected to locking means provided on the dispensing piston. This allows a very simple repeated use of this arrangement for self-dispensing by patients, and remote wounds, e.g. an arm or foot wound, can also be treated by the patient independently.

Abstract: A pen injection device designed for use with dual or multi-chamber cartridges (14), is provided with an extended length plunger (24) having a non-drive portion (24?) on its forward end and the usual screw-threaded drive portion (24?) on its rearward end. This arrangement allows the plunger to be pushed forwardly whilst the dosing drive mechanism is disengaged to effect a reconstitution movement of the rearward bung (18?) in the cartridge. Thereafter the threaded portion on the plunger (24?) engages the drive mechanism to allow metered dosing.

Abstract: A cannula insertion device includes a housing defining an opening for receiving therethrough a cannula and further defining a channel, and a cannula forming a lumen, the cannula adapted for sliding movement within the housing from a retracted position to an extended position. When the cannula is in the retracted position, the lumen is located remotely from the channel and the channel is in fluidic communication with the opening. When the cannula is in the extended position, the lumen is in fluidic communication with the channel.

Abstract: An injection device (110) comprises a housing (112) adapted to receive a syringe (116) having a discharge nozzle (118) and dispensing piston (114) movable in the syringe to expel the contents of the syringe through the discharge nozzle. There is also a drive (130) adapted to act on the syringe to advance it from a retracted position in which the discharge nozzle is contained within the housing to an extended position in which the discharge nozzle extends from housing. A drive coupling (134) extends from the drive to the dispensing piston of the syringe so as to transfer movement of the drive to the piston. The drive coupling comprises a fixed-length drive-coupling and an interchangeable drive coupling. There is also a method of manufacturing an injection device by assembling a first sub-assembly (210) and second sub-assembly (220).

Abstract: An infusion medium delivery system, device and method for delivering an infusion medium to a patient-user, includes a needle inserter device and method for inserting a needle and/or cannula into a patient-user to convey the infusion medium to the patient-user. The needle inserter device and method operate to insert a needle and cannula into a patient-user's skin and automatically withdraw the needle from the patient-user, leaving the cannula in place and in fluid flow communication with a reservoir. The delivery device may include a base portion and a durable portion connectable to the base portion, and wherein the base portion can be separated from the durable portion and disposed of after one or more specified number of uses. The base portion supports the reservoir and the needle inserter device, while the durable portion supports a drive device for selectively driving the infusion medium out of the reservoir and into the needle and/or cannula.

Abstract: A medical device is provided comprising a cannula having a distal portion adapted to be arranged through the skin of the subject, and an outer needle arranged coaxially with and being axially moveable relative to the cannula, the needle comprising a pointed distal end, wherein the device is adapted for advancing the cannula with the distal end of the needle projecting there from through the dermis of the subject, and subsequently retract the needle.

Abstract: A medicinal container engagement and automatic needle device including an automatic needle assembly and a medicinal container receptacle removably joined to the automatic needle assembly.

Abstract: An injection device 110 is described having a housing 112 that receives a syringe 114 having a needle 118, wherein the syringe is supported in a syringe carrier 150. The syringe 114 and syringe carrier 150 are biased by a return spring 126 from an extended position in which the needle 118 extends from the housing 112 through an exit aperture 128 to a retracted position in which it does not. A drive spring 130 acts via a drive to advance the syringe 114 from its retracted position to its extended position and discharge its contents through the needle 118 and a return spring 126, brought into play when the drive has reached a nominal return position, restores the syringe 114 to its retracted position. The injection device is less prone to failure than prior art devices and is safer should failure occur.

Abstract: An injection device (210) is described. A housing (212) receives a syringe and includes a return spring (226) for biasing the syringe from an extended position in which its needle (218) extends from the housing (212) to a retracted position in which the it does not. A drive spring (230) acts on a first drive element (232) and a second drive element (234) acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the needle. The first drive element (232) is capable of movement relative to the second (234) once a nominal decoupling position has been reached. A release mechanism is activated when the first drive element (234) is further advanced to a nominal release position, to release the syringe (214) from the action of the drive spring (230), whereupon the return spring (226) restores the syringe (214) to its retracted position. A locking mechanism (337, 375) confines the returned syringe in its retracted position.

Abstract: An injection device (210; 110) is described. A housing (212; 112) receives a syringe and includes a return spring (226; 126) for biasing the syringe from an extended position in which its needle (218; 118) extends from the housing (212; 112) to a retracted position in which the it does not. A drive spring (230; 130) acts on a first drive element (232; 132) and a second drive element (234; 134) acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the needle. The first drive element (232; 132) is capable of movement relative to the second (234; 134) once a nominal decoupling position has been reached. A release mechanism is activated when the first drive element (234; 134) is further advanced to a nominal release position, to release the syringe (214; 114) from the action of the drive spring (230; 130), whereupon the return spring (226; 126) restores the syringe (214; 114) to its retracted position.

Abstract: When a cover (10) of a syringe firing mechanism is pushed downwardly towards a housing (2) a flexible arm (12) is moved inwardly to release a trigger (8). This enables a drive member (6) to push down a plunger (5) of the syringe under the bias of a spring (7). When the injection is completed, release of the cover (10) causes the cover (10) to move back into contact with a corner of the drive member (6). A cam surface (15A) then pushes a flap (16) across, whilst bending a hinge (17), until the flap (16) enters the hollow interior of the drive member (6), thus enabling the syringe (1) to be withdrawn within the housing (2) under the bias of a spring (3).

Abstract: An injection device including casing with a reservoir for an injectable product, an operating button which can be moved relative to the casing in a dosing direction which increases the dosage and in a correcting direction to set a product dosage, a conveying member for delivering the dosage set, a slip coupling comprising a latching element and a co-operating latching element which latch to each other in a latching engagement and couple the operating button to the casing in a positive and non-positive fit in discrete latching positions during a movement in the dosing direction or the correcting direction, and a spring member which opposes the movement of the operating button in at least one of the directions with a spring force, wherein the latching element or co-operating latching element are shaped such that in the latching engagement they offer a lower resistance to the movement in the at least one of the directions than to the movement in the other direction.

Abstract: A plug-on body which can be plugged onto a device for administering a settable dosage of an injectable product, the plug-on body including a first plug-on body section extending axially in the direction of a plug-on body axis for fixing the plug-on body to a dosing and activating means, a shifting stopper formed by the first plug-on body section and operating by positive lock for axially fixing the plug-on body with respect to at least one shifting direction, a rotational stopper formed by the first plug-on body section and operating by positive lock for fixing the plug-on body against rotating, a second plug-on body section extending behind the first plug-on body section in the direction of the plug-on body axis, wherein said second plug-on body section forms an optics system for reading a dosage scale on a dosing element of the device which serves to set the dosage.

Abstract: Methods and apparatus are provided for treating damaged tissue using apparatus that atraumatically delivers a bioactive agent within the tissue, wherein the apparatus provides a column of stem cells may be advanced simultaneously with a needle during needle insertion, and then held stationary or injected at low pressure while retracting the needle. Alternatively, the needle may employ electromotive forces, or to change a dimension of the needle, to expel the bioactive agent into the needle track.

Abstract: A device for delivering a dose of medicament includes a generally elongated housing, a container containing medicament to be injected through a needle, a force device acting on the container and capable of, upon activation, moving the container and the needle for penetration and subsequently expelling medicament through the needle, and an activating device arranged to activate the force means. The activating device includes a needle shield slidably arranged in relation to the housing, which upon movement releases the force device, and a release device arranged in the front, injecting, area of the device, which, when in a non-activated state prevents the needle shield from sliding, thereby preventing activation, and when activated, enables sliding of the needle shield and thereby activation of the device. The release device is arranged on the device such that it promotes an ergonomic grip of the device for its activation.

Abstract: A one-way injector having a housing in which at least one mechanical spring energy store, at least one piston/cylinder unit, which can be at least temporarily filled with an active substance, at least one piston-actuating plunger and at least one tripping unit are arranged. To this end, the spring energy store comprises a preloaded spring element. The spring element is held in the preloaded position by a tension means surrounding at least a region of the spring. The tripping unit comprises a cutting tool which, in order to release the energy of the spring energy store, severs or weakens the tension means at least one point, the weakening immediately tearing the tension means. With the present invention, a one-way injector is developed which, with a small overall size, has only a few components and ensures reliable mounting and functioning with simple manipulation.

Abstract: In the present invention, the impedance between patient's body and the jet injection drug delivery device is measured through the liquid jet during the drug delivery process. The liquid jet completes the electrical circuit formed by impedance monitor, drug delivery device, and the patient's body. When the jet pierces stratum corneum, the impedance in the circuit immediately decreases, thus an indicating the successful drug delivery. The impedance monitor then provides a signal, visible, audible, or electronic, indicating that the process of the drug delivery through skin was successful.

Abstract: An auto-injector confines all functional components inside an enclosed housing, to keep its needle out-of-sight, at all times. Within the housing, a needle holder positions a needle at a location. A drive mechanism then simultaneously engages the needle with a fluid source and accelerates it with a predetermined momentum for insertion into a patient. After fluid delivery, the withdrawn needle is moved to storage within the housing for subsequent disposal.

Abstract: The invention relates to an injector device for an infusion set for intermittent or continuous administration of a therapeutical substance, such as insulin. The injector device for the subcutaneous introduction of the cannula of an infusion part into the skin of a patient comprises a housing, a back, longitudinally extending guiding means, a member which is longitudinally slidable within the housing, an insertion needle for insertion of the cannula, a spring located between the back of the housing and the longitudinally slidable member, locking means for maintaining the spring in a compressed state and release means for disengaging the locking means. The device further comprises a pivoting member which can be swung from a position in which the pivoting member allows for insertion of the needle into a position in which it embraces the needle.

Abstract: An insertion device and insertion set. The insertion device for inserting at least a portion of at least one piercing member of an insertion set through the skin of a patient includes a device housing, a carrier body and a driver. The carrier body is slidably received within the device housing for movement between an advanced position and a retracted position. The carrier body also includes a receiving structure to support the insertion set in a position with the at least one piercing member oriented for insertion through the skin of the patient at a predetermined angle relative to the skin of the patient upon movement of the carrier body from the retracted position to the advanced position.

Abstract: An insertion device and insertion set. The insertion device for inserting at least a portion of at least one piercing member of an insertion set through the skin of a patient includes a device housing, a carrier body and a driver. The carrier body is slidably received within the device housing for movement between an advanced position and a retracted position. The carrier body also includes a receiving structure to support the insertion set in a position with the at least one piercing member oriented for insertion through the skin of the patient at a predetermined or variable angle relative to the skin of the patient upon movement of the carrier body from the retracted position to the advanced position.

Abstract: A fluid filled cartridge having a fixed needle and a piston assembly for expression of its contents is mounted inside an applicator. In order to extend the needle from the body prior to cartridge contents expression and without premature leakage of fluid therefrom, an actuator is mounted in the body to drive the cartridge forwards. This is accomplished by co-operating driving and driven parts of the actuator and the cartridge (or any carrier it may have) which are decoupled by release formations in the applicator body after the cartridge has been moved sufficiently to extend the needle. The applicator also includes provision for automatic needle retraction after cartridge contents expression. A separate inventive feature is the deformability of the piston so that force transmission to the trigger means to initiate needle retraction only occurs upon full content expression when the piston has “bottomed out” within the cartridge.

Abstract: A reloadable medicine injector and methods are described in which a barrel with a receiving cavity is adapted to slidably receive a syringe subassembly for axial movement therein. Upon removal of a safety and release of a syringe driver, the syringe driver moves forward and injects the syringe needle. A plurality of penetration controls are shown for controlling injection needle penetration depth. The penetration controls have an abutment and various lengths to provide different needle penetration depth positions. In one form of penetration control a sleeve is used against which the syringe or related parts contact. In another form the front return spring is used as a penetration control. A cushioning ring may be used to reduce syringe breakage. A load distribution and guide ring may be used to distribute loading applied to the syringe and help guide the moving syringe.

Abstract: An insertion device for inserting at least a portion of at least one piercing member of an insertion set through the skin of a patient, including: a device housing and a carrier body for movement between an advanced position and a retracted position. The carrier body includes a receiving structure to support the insertion set in a position with the at least one piercing member oriented for insertion through the skin of the patient at a predetermined angle relative to the skin of the patient. A driver urges the carrier body with a controlled force and speed to place at least a portion of the at least one piercing member of the insertion set through the skin of the patient to install the insertion set to the patient. The receiving structure is removable from the insertion set while maintaining installation of the insertion set to the patient.

Abstract: An autoinjector including a housing, a receptacle for an active substance, which receptacle, together with a connected injection needle, is displaceable within the housing by spring force for inserting the injection needle into a patient, a piston displaceable within the receptacle by spring force for expelling the active substance, a transfer mechanism for transferring the spring force to the receptacle and/or to the piston, a holding mechanism for holding the transfer mechanism, a releasing mechanism for causing the holding mechanism to release the transfer mechanism when the releasing mechanism is moved from a first position into a second position, and a resetting mechanism for moving the releasing mechanism from the first position into the second position without during the move causing the transfer mechanism to be released.

Abstract: An apparatus for administering a substance, including a housing, a piston, a container and a propelling device, the propelling device including a base element, a first shifting stage shiftable relative to the base element, and a second shifting stage shiftable relative to the base element and to the first shifting stage and slaving the first shifting stage, wherein the propelling device, container and piston are operably coupled to the housing and the first shifting stage is in contact with the piston.

Abstract: A system for inserting at least a portion of an insertion set through the surface of a tissue, having: an inserter with a moveable plunger disposed within a cavity therein; an insertion set holder received into the distal end of the cavity; and an insertion set received into the insertion set holder, wherein the insertion set is moveable within the insertion set holder such that when the plunger is advanced into contact with the insertion set, the insertion set advances through the insertion set holder to a position at which at least a portion of the insertion set extends out of the distal end of the cavity.

Abstract: The syringe (10) for self-injecting an extemporaneous mixture comprises: a body (60) containing at least two substances (36, 38) initially separated by an intermediate piston (32), which body (60) has two relatively movable portions (64, 66) that are movable between an initial position in which the two substances (36, 38) are separate and a final position in which the two substances (36, 38) are mixed together to form an extemporaneous mixture; automatic means (70, 72) for injecting the extemporaneous mixture out from the body (60) in order to proceed with injection; and latch means (73) for preventing triggering of the automatic injection means (70, 72). The syringe includes locking means (154, 109) for locking the latch means (73) so as to prevent the automatic injection means (70, 72) being triggered until the two substances have finished being mixed together.

Abstract: A device for administering an injectable product in doses, wherein the device includes a casing, a reservoir for the product, a piston, an advancing element which moves the piston a selected path length, and a dosing mechanism including a number of dosing bodies and a dosing element operable to move the dosing bodies, wherein the path length is selected by the dosing element moving at least one dosing body between the piston and the advancing element.

Abstract: An injector device has a plunger with a medical needle essentially non-detachably secured thereto, preferably a solid needle incapable of delivering a fluid, and is adapted for the quick and easy transcutaneous placement through the skin of a patient of the cannula of a subcutaneous infusion set, the insertion needle extending through the infusion set and protruding from the end of the cannula.

Abstract: A needle device comprises a housing, a base portion having a mounting surface adapted for application to the skin of a patient, and a plurality of needles. Each needle comprises a distal pointed end adapted to penetrate the skin of the subject, and has a first position in which the distal end is retracted relative to the mounting surface, and a second position in which the distal end projects from the mounting surface. The needles are arranged such that at least one needle can be moved from its first to its second position, or vice versa, with at least one other needle not performing the same movement. In this way a plurality of needles can be introduced transcutaneously at a selected site within the body of a subject. The device may comprise a common fluid conduit with at least two of the needles having a proximal opening to be arranged in fluid communication with the common fluid conduit.

Abstract: A first embodiment of an automatic injector employs less material and fewer parts by eliminating an outer housing required in earlier automatic injectors. In a second embodiment, a manually operated sharps protector is provided. In a third embodiment, the sharps protector is deployed by a spring positioned internally of the sharps protector. In a fourth embodiment, the sharps protector is deployed by a spring positioned externally of the sharps protector. In all embodiments, removal of a safety cap enables a user to press on an outer gun sleeve that displaces in an axial direction and releases the trailing end of a spring holder so that a compressed spring that bears against the spring holder unloads and drives a piston that displaces a cannula into the tissue of a user, followed by a liquid medicament injection through the cannula.

Abstract: A tranquilizer bracelet which can be locked onto A wearer's wrist. The bracelet contains A power source, an electronic control module, and means for injecting A tranquilizing agent into the wearer. Instructions can be sent to the control module remotely, such as by using radio transmissions. The bracelet is provided with A lock to secure it to the wrist. It can only be opened using A mechanical key or electronic code. Thus, once the bracelet is installed, it cannot be removed by the wearer. In the event that tranquilization is necessary, A remote signal is sent to the control module. The signal activates A mechanism within the bracelet which causes the injection of the tranquilizing agent. Anti-tampering mechanisms are also provided, which will produce an alert signal if the bracelet is somehow removed by the wearer.

Abstract: An injector pack has a box which houses in separate positions a firing mechanism and a syringe housing. The firing mechanism has safe and cocked conditions and as it is located in the box it is constrained to adopt the safe condition by a sleeve grip being held against rotation while a protruding barrel co-operates with cams to rotate it. The firing mechanism when removed can be screwed by its barrel to the rear end of the syringe housing while that is held by the box, and then the whole injector can be withdrawn for use. The syringe is made operable by rotating the barrel to the cocked condition. Pressing the grip forwards then releases a plunger to act on the syringe. The previous retraction of the plunger can be done using a pillar formation upstanding within the box and over which the barrel can be sleeved.

Abstract: A device for auto-injection of a dose of medicament, comprises a housing arranged to contain a medicament container therein and a contact part intended to be applied against an injection site, a needle cover surrounding a needle arranged to the medicament container and extending at least the length of the needle, spring elements for, upon activation, pushing the needle past the end of the cover as well as operating the medicament container to supply the dose of medicament, first locking elements for locking the spring elements in a pressurized state, first activating elements for, upon manual operation, releasing the spring elements for injection. There is a second locking element capable of locking the first activating element and a second activating element, capable of releasing the second locking element when the contact part is exposed to pressure.

Abstract: The present invention includes an automatic injection device that reliably provides automatic needle retraction even when manufactured with part and assembly tolerances typical of low-cost and high-volume manufacturing processes. The injector of the present invention includes a body, a syringe cartridge, a drive mechanism, and a bias mechanism. The drive mechanism includes an energy source, a drive member, and a compound plunger with a releasable coupling. Significantly, the compound plunger included in the drive mechanism is designed to ensure needle retraction occurs after the automatic injection device has delivered the desired the desired dose of medicament. Moreover, the design of the compound plunger included in the injector of the present invention can compensate for part and assembly tolerances typical of low-cost, high volume manufacturing processes, enabling the fabrication of a low cost automatic injection device providing reliable automatic needle retraction.

Abstract: An insertion device and insertion set. The insertion device for inserting at least a portion of at least one piercing member of an insertion set through the skin of a patient includes a device housing, a carrier body and a driver. The carrier body is slidably received within the device housing for movement between an advanced position and a retracted position. The carrier body also includes a receiving structure to support the insertion set in a position with the at least one piercing member oriented for insertion through the skin of the patient at a predetermined or variable angle relative to the skin of the patient upon movement of the carrier body from the retracted position to the advanced position.

Abstract: An insertion device and insertion set. The insertion device for inserting at least a portion of at least one piercing member of an insertion set through the skin of a patient includes a device housing, a carrier body and a driver. The carrier body is slidably received within the device housing for movement between an advanced position and a retracted position. The carrier body also includes a receiving structure to support the insertion set in a position with the at least one piercing member oriented for insertion through the skin of the patient at a predetermined or variable angle relative to the skin of the patient upon movement of the carrier body from the retracted position to the advanced position.

Abstract: An injection device has a housing (12) in which a container (14) for receiving an injectable fluid (18) is longitudinally movable. To its proximal end, an injection needle (26) can be releasably coupled. The injection device has a spring (50) associated with a releasable detent (52) for latching this spring (50) in a cocked configuration (FIG. 2). Further, there is a cocking member (40) insertable into the proximal end of the housing (12) for moving the longitudinally movable container (14) in the distal direction and for thereby bringing the spring (50) into the cocked configuration.

Abstract: The present invention is directed to a drug delivery device. The device includes an interior chamber and a seal structure. In accordance with the present invention, the interior chamber may include a first, liquid medicament compartment and a second medicament compartment. The seal structure is conditionable to permit fluid to pass therethrough upon pressurization of the fluid. The seal structure preferably includes a sealing member which moves from a first sealed position into a second by-pass position upon pressurization of the liquid injection solution in the wet compartment of the housing assembly. Such by-pass movement of the sealing member enables the liquid injection solution to flow through the seal structure into the second ingredient compartment and mix for injection.

Abstract: An insertion device and insertion set. The insertion device for inserting at least a portion of at least one piercing member of an insertion set through the skin of a patient includes a device housing, a carrier body and a driver. The carrier body is slidably received within the device housing for movement between an advanced position and a retracted position. The carrier body also includes a receiving structure to support the insertion set in a position with the at least one piercing member oriented for insertion through the skin of the patient at a predetermined or variable angle relative to the skin of the patient upon movement of the carrier body from the retracted position to the advanced position.