Abstract: An injection device for administering a substance, including a housing, a plunger rod which can be moved relative to the housing, at least one retaining element associated with the rod to hold the rod relative to the housing, and a displaceable locking sleeve which can be displaced relative to the housing from one position in which the sleeve holds the at least one retaining element in a retaining position to a second position in which the at least one retaining element is released.

Abstract: Intelligent (smart) tracking accessories for a medicine dispensing device, such as an injection pen or pen device, are described. A smart tracking accessory in the form of a smart cap for a medicine dispensing device, such as an insulin pen, is configured to protect the needle of the dispensing device and the medicine contained therein when the device is not in use. The smart cap may detect the presence of the medicine dispensing device, detect an activation event such as removal from the medicine dispensing device, inform the user whether it is safe to administer a therapeutic dose of medicine, and log occurrence of the dosing event.

Abstract: An intraosseous device may include a chamber portion having a proximal end and a distal end, wherein the proximal end includes a base, a tensile puller configured to extend through the chamber portion and slidingly engage the base, the tensile puller comprising a proximal end and a distal end, an actuator on the proximal end of the tensile puller, and a connector on the distal end of the tensile puller adapted to engage a needle.

Abstract: An injection device for injecting, the injection device comprising a housing having an interiorly facing wall with the wall having a plurality of ribs formed thereon, the ribs defining a channel extending therebetween, a plunger rod mountable within the housing and having at least one protrusion engageable within the channel, a cylindrical body, a spring mounted at a distal end of the housing with the spring being biased between the distal end and a needle hub, and a pusher rod raised such that pressure thereon from the plunger rod will cause the pusher rod to enter the cylindrical body, the pressure causing the spring to act on the needle hub to move the needle hub and the cylindrical body upwardly within the housing such that a needle is in an enclosed position within the housing and cannot be reused.

Abstract: A transport lock assembly for a medicament delivery device, wherein the transport lock assembly comprises a powerpack (30) having a locking member (50, 50?, 50?) configured to interact with a control member (60), which locking member (50, 50?, 50?) is movable, relative to the control member (60), from a first state in which the control member (60) is immobilized, to a second state in which the control member (60) is free to move; wherein the transport lock assembly further comprises a housing part (20) having a key member (22), such that assembly of the powerpack (30) with the housing part (20) causes the key member (22) to move the locking member (50, 50?, 50?) from the first state to the second state.

Abstract: The present disclosure relates to an autoinjector device for use in combination with a syringe, said syringe comprising a movable plunger; a needle; and a tubular needle shield. The claimed autoinjector device comprises: an elongated housing having a proximal and a distal end; a drive mechanism; a syringe holder in order to support the fragile syringe and to prevent damage to the syringe. The invention furthermore relates to a method for assembly of the autoinjector device according to the invention.

Abstract: In one embodiment there is an injector comprising a housing having a proximal end and a distal end, a shell, a plunger, a needle guard, a first member, and an actuation assembly. The shell may be within the housing and may have a cavity to receive at least a portion of a medicament chamber. The shell may be moveable with respect to the housing from an initial position to an injecting position. The plunger may be moveable with respect to the shell. The needle guard may be moveable between an extended position and a retracted position. The first member may be within the housing. The actuation assembly may be coupled to the housing and the shell. The needle guard may move the first member with respect to the housing as the needle guard moves from the extended position to the retracted position. The actuation assembly may move the shell from the initial position to the injecting position when the first member moves with respect to the housing.

Abstract: A drug delivery device includes a casing and a storage container with a dose delivery member, at least a portion of which extends through an opening in the casing. A guard is movable relative to the casing between extended and retracted positions. The guard surrounds the extended portion of the dose delivery member in the extended position, and exposes the extended portion in the retracted position. An interference arrangement is included for providing selected threshold of resistance to movement of the guard from the extended position to the retracted position during insertion of the dose delivery member into body tissue. The arrangement has first and second members engaging one another to retain the guard in the extended position. The first or second member can move if the selected threshold of resistance is exceeded to allow the members to slide and allow the guard to move into the retracted position.

Abstract: A grip accessory for a manual injection device comprises a housing comprising a generally hollow body configured to support a manual injection device therein. The housing comprises a distal portion comprising a first opening into which a manual injection device can be inserted, a proximal portion having a second opening through which the needle of the manual injection device extends. The proximal portion comprises a skin contacting surface at a proximal end of the device that can be placed against an injection site. An intermediate portion extends between the proximal and distal portions.

Abstract: A method includes protecting an entire length of a needle of a needle-based device protruding from a needle mount coupled to a body thereof based on providing a needle shield completely encompassing the entire protruding length of the needle in a first state of disuse, and retracting the needle shield in a first direction toward the body of the needle-based device to apply a first force in the first direction to cause the needle to emerge out of the needle shield to prepare the needle-based device for a second state of use. The method also includes transitioning the needle-based device back to the first state of disuse following the second state of use in accordance with applying a second force in a second direction diametrically opposite to the first direction, and providing a lock button to lock the needle shield in the first state of disuse.

Abstract: The present disclosure relates to a sheath remover for removing a protective needle sheath from a drug cartridge. The sheath remover includes a resilient ring and one or more resilient legs attached to the ring and extending in a proximal direction. Each leg includes an inwardly directed ledge arranged at a proximal end of the leg. The ring consists of a resilient material allowing inward deflection of a proximal end of the ring. The present disclosure further relates to a method for assembling and a method for using the sheath remover.

Abstract: The present invention relates to a protection device (1) intended to at least partially cover the needle (2) of an injection device, comprising: a support (3) of the protection device (1), a sleeve (4) movable axially in translation with respect to the support (3), an arrangement (14) for returning the sleeve (4) from an injection position to a protection position, an axial guidance arrangement (29, 30) for preventing the sleeve (4) from pivoting with respect to the support (3), one peg (6) directly and at least elastically, coupled longitudinally to the support (3) or the sleeve (4) and housed in a passageway (10) defining a first section (11) and a second section (12) followed by the peg (6) from a storage position to the injection position and then to the protection position, and a safety arrangement (21; 36, 34, 35) part of which being elastically deformable, arranged in a way as to prevent the peg from returning from the second section to the first section.

Abstract: The invention relates to an auto injector, by which a fixed dose of a medicament can be injected as self-treatment, and by which needle exposure to an accessible position, injection of the medicament and retraction of the needle to an inaccessible position is automatically performed as a continuous sequence, after the auto injector is triggered. The invention provides solutions to improve the functionality of the retraction of the needle and the general experience of the use.

Abstract: An autoinjector includes a case adapted to hold a medicament container having a needle telescopically coupled to the case and movable between a first extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed. The autoinjector includes a plunger rotationally and slidably disposed in the case rotatable relative to the case between a first rotational position in which the plunger is engaged to the case and a second rotational position in which the plunger disengages the case engages the plunger to rotate the plunger from the first rotational position to the second rotational position when the needle shroud translates from the first extended position to the retracted position. The autoinjector includes a cap removably coupled to the case includes at least one compliant case beam adapted to releasably engage at least one aperture in the case.

Abstract: Devices and methods for a compact injector are provided with a compact configuration for ease of carrying or storage, and an activated configuration ready for injection. In the compact configuration, a plunger and a needle are both retracted into the injector housing, and upon actuation to the activated configuration, the plunger extends proximally and the needle extends distally, ready for injection. An extendable needle shield is also provided to block visibility of the needle during injection, and to reduce the risk of inadvertent needle stick at other times, including disposal.

Abstract: According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.

Abstract: A medicament delivery device is presented having a medicament container having an attached medicament delivery member; a housing where the medicament container is movable between a retracted and an extended position in which the medicament delivery member extends from the housing; a drive unit that advances the medicament container from its retracted position to its extended position to expel the contents through the medicament delivery member; and a medicament container holder for carrying the medicament container as it is advanced, the medicament container holder having a proximal end through which the medicament delivery member extends and a holding member releasably connected to the drive unit and attached to the medicament container holder.

Abstract: A hand-held ultrasound system includes integrated electronics within an ergonomic housing. The electronics includes control circuitry, beamforming and circuitry transducer drive circuitry. The electronics communicate with a host computer using an industry standard high speed serial bus. The ultrasonic imaging system is operable on a standard, commercially available, user computing device without specific hardware modifications, and is adapted to interface with an external application without modification to the ultrasonic imaging system to allow a user to gather ultrasonic data on a standard user computing device such as a PC, and employ the data so gathered via an independent external application without requiring a custom system, expensive hardware modifications, or system rebuilds.

Abstract: A drug delivery device includes a container for storing a drug having a longitudinal axis. A plunger rod aligned with the longitudinal axis of the container has a first end and a second end, where the second end is disposed within the container. A stopper is disposed in and movable relative to the container for expelling the drug, and a drive mechanism is operatively coupled to the first end of the plunger rod. The drive mechanism is configured to deliver a drive force to move the plunger rod along the longitudinal axis and through the container. A chamber disposed between a plunger rod and the stopper is adapted to oppose the drive force of the drive mechanism.

Abstract: A needle protection assembly, adapted to protect a tip of a hypodermic needle, comprising a shield adapted, in a protected operative orientation of the needle protection assembly, to shield the tip of the hypodermic needle, a locking element including at least one slot, the slot including at least three surfaces corresponding to three operative orientations of the shield, at least one slot engaging element, functionally associated with the shield, the slot engaging element being disposed within the slot of the locking element and movable relative thereto, between the surfaces, so as to transition the shield between the three operative orientations, and at least one biasing element, adapted for axial biasing of the shield, wherein the three operative orientations include a storage operative orientation, an injection operative orientation, and a needle protection operative orientation.

Abstract: A needle assembly is disclosed, which includes a needle protection member and a rotor. The rotor has a rotor body and a restriction portion. When the needle protection member in the initial state is displaced from the protection position to a use position and returns to a protection position, the restriction portion is displaced from the initial position to the lock position by the rotation of the rotor body with respect to the needle protection member. A needle hub has a displacement prevention portion that prevents the needle protection member from being displaced from the protection position to the use position again by contacting the restriction portion at the lock position.

Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.

Abstract: A blood sequestration device configured to isolate an initial, potentially contaminated portion of blood from the flow of blood of a patient, prior to directing the flow of blood to an outlet port where the blood can be accessed. The blood sequestration device including a body member having an interior wall defining a fluid conduit having a distal portion, a first proximal portion, and a second proximal portion, wherein the first proximal portion defines a sequestration chamber configured to isolate an initial portion of blood of a flow of blood, a vent path configured to enable the escape of gas initially trapped within the sequestration chamber.

Abstract: The present invention provides a needle unit (10) for use with a pen injection device, wherein the needle unit (10) comprises a needle shield (50) and an axially movable needle hub (25).

Abstract: An apparatus for use with a syringe for providing a safety syringe, the safety syringe including a plunger configured during an inward stroke to expel a substance from a hypodermic needle attached at an open end of a barrel of the syringe, the apparatus including: a biasing member configured to bias a sheath towards a closed position at least partially covering the hypodermic needle, wherein the biasing member is configured to be released at a point on the inward stroke of the plunger to urge the sheath towards the closed position.

Abstract: A syringe assembly is provided comprising a syringe cylinder extending from an opening configured to receive a plunger to an end configured to couple with a needle and/or medical tubing, a cap configured to couple to the end, and barrier material at least partially encompassing the cap and the end. A syringe assembly is provided comprising a syringe cylinder extending from an opening configured to receive a plunger to an end configured to couple with a needle and/or medical tubing, a plunger extending from one end to a seal end, and at least one cap configured to couple to the one end. A syringe assembly is provided comprising a syringe cylinder extending from an opening configured to receive a plunger to an end configured to couple with a needle and/or medical tubing, and a plunger extending from one end to a seal end, the one end of the plunger defining a recess configured to receive at least one cap.

Abstract: An injection device comprising a housing (112), and a dose selector (116) operatively connectable to a dose indicator positioned within the housing. The dose selector and the dose indicator (118, 119) are capable of cooperating to set a dose to be ejected from the injection device. The injection device further comprises a spring (120) capable of storing energy necessary for ejecting the dose from the injection device. The spring is locked to the dose indicator such that a charging force can be transferred from the dose selector to the spring via the dose indicator to increase the energy stored by the spring.

Abstract: The invention relates to a needle protection device for a pre-filled syringe with staked needle. This device comprises a blocking mechanism, comprising means for fastening to a syringe body, a needle shield, into which the needle can be driven, and an after-use safety system comprising a sleeve defining a central axis along which it is movable and means for resiliently loading the sleeve in a forward position in which it is able to cover the needle. The sleeve comprises an outer tube and a coaxial inner tube that are manufactured in one piece by injection molding, while the outer tube is arranged so as to cooperate with the blocking mechanism, and the inner tube is detachable from the outer tube and axially connected in translation with the needle shield.

Abstract: In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors distributed pre-filled and with the springs tensed may be provided with a needle protecting cap to ensure sterility of the needle. When the needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container and needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve accommodating the active agent container. When the auto-injector is placed onto the skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange, thereby freeing the travel path for needle movement.

Abstract: The invention relates to a safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly having: an attachment ring fixed to the tip of the container and a safety device to cover at least the distal end of the needle, the safety device attached to the attachment ring. The safety assembly has an attachment ring having an inner ring and an outer ring to be snapped onto each other, the inner ring having an inner recess for applying glue between the inner ring and the tip, and the inner ring and outer ring having mutually engaging elements preventing any rotation of the outer ring relative to the inner ring.

Abstract: An at least partly implantable system for injecting a substance into a patient's body. The system comprises at least one flexibly bendable infusion needle with a tip end of each of said at least one infusion needle arranged in at least one first housing for penetrating the first housing's outer wall in at least one penetration area and having the respective other end arranged in at least one second housing, the first and second housings being adapted for implantation inside the patient's body, wherein the at least one second housing is provided for implantation inside the patient's body remote from the at least one first housing and wherein the injection needle is sufficiently long to bridge the distance from the at least one second housing for remote implantation to the at least one first housing and further through the first housing up to the outer wall of the first housing.

Abstract: A medicament delivery device (100) for delivery of medicament from a container (12) into an injection site through a cannula (16). The device comprises a chassis (106), a drive mechanism (400) for driving a piston member (22) along a container axis (A) to expel the medicament through the cannula (16), and a carriage (200) for retaining the container (12), the cannula (16) and the drive mechanism (400). An insertion mechanism (70, 120, 130, 504) is provided for moving the carriage (200) in an insertion direction (H) relative to the chassis (106), and a cannula bending mechanism (300) is provided for bending the cannula (16) about a bending axis (B) to substantially align at least an end part of the cannula (16) with the insertion direction (H) prior to movement of the carriage (200) in the insertion direction (H).

Abstract: A medical injection device for supporting a medical container, the medical container comprising a barrel adapted to contain a composition and a needle extending from a distal end of the barrel, wherein the medical injection device comprises: a body configured to receive at least a part of the medical container, a plunger axially movable relative to the body along an axis of the body, needle cover movable relative to the body along the axis, the needle cover being configured to move successively between storage position wherein the needle cover covers the needle, an injection position wherein the needle cover exposes at least partially the needle, a safety position wherein the needle cover covers the needle and is prevented from moving back to the injection position.

Abstract: A needle end and a safety syringe are provided, belonging to technical field of medical instruments. The safety syringe includes an injection end, a liquid storage device, and a base. The injection end includes a needle base, an injection needle, and a needle guard assembly. The injection needle is fixed to the needle base. The needle guard assembly is connected to the needle base. The needle guard assembly includes a protective casing and a spring, wherein a first terminal of the spring is connected to the needle base and a second terminal of the spring is connected to the protective casing. The liquid storage device includes a liquid storage container and a liquid storage sleeve. The liquid storage is sleeved on an outer surface the liquid storage container, wherein the liquid storage container is detachably connected to the injection end. The base is detachably connected to the liquid storage device.

Abstract: A discharger for discharging a predetermined amount of fluid from a separate container including a discharge section defining a longitudinal axis and having a proximal end and a distal end and having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section. The discharger further includes an intermediate section including a distal portion cooperating with the proximal end of the discharge section and a proximal portion defining a receiving space which is adapted to be loaded with the separate container holding an amount of fluid to be discharged by the discharger. The distal portion and the proximal portion are formed in one piece and are interconnected by a breakable section.

Abstract: A nicotine powder delivery system includes an inhaler article and a nicotine powder capsule disposed within the inhaler article. The nicotine powder capsule rotates about a longitudinal axis when air flows through the inhaler article.

Abstract: Disclosed is an injection device for receiving a syringe therein and for delivering a dose of medicament from the syringe, the injection device including: an insertion driver configured to drive the syringe forwards within the injection device for inserting a needle of the syringe into an injection site; an interlock mechanism configured to retain the insertion driver in a primed state and, when actuated, to allow the insertion driver to drive the syringe forwards; and an interlock actuator moveable between a stowed position and an operable position and configured on movement from the stowed position to the operable position to couple to an actuation system such that movement from the operable position back towards the stowed position actuates the interlock mechanism.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. The cartridge includes a vacuum bellows that surrounds the needle when the bellows is in an extended configuration. The vacuum bellows is compressible to expose the needle and generates a vacuum condition within the bellows when the bellows is extended from a compressed configuration to the extended configuration. The needle may be a dual-lumen plastic needle.

Abstract: A feedback mechanism for an injection device that is configured to deliver a medicament to a user is described. The feedback mechanism comprises a piston and a fluid chamber, and the piston is adapted to move into the fluid chamber during use of the injection device. The feedback mechanism also has a damper that is arranged to damp movement of the piston, and an indicator that is arranged to provide feedback to the user after the piston has moved a pre-determined distance into the fluid chamber.

Abstract: The present invention suppresses the amount of fluid pushed out from an injection needle when confirming whether air has been pushed out of the injection needle. Provided is a syringe that comprises: a cylinder 20; an injection needle 22; a needle base 24; an injection needle cover 26; and a plunger rod 28. The needle base 24 communicates between the inside of the cylinder 20 and the inside of the injection needle 22. The injection needle cover 26, when extended from a folded state, surrounds the injection needle 22. The injection needle cover 26 comprises an injection needle surrounding part. The injection needle surrounding part has at least one cutout 130 in a section facing the needle base 24 and covering the needle base, such that the needle base 24 can be identified from the outside.

Abstract: A safety pen needle includes: a main body, a cannula fixed to the main body and at least partially projecting out of the main body, a lock element placed inside the main body, a thrust element placed inside the main body, and a shield movable relative to the main body while remaining at least partially inserted within the main body. The pen needle is configured to move from a first configuration, in which the shield entirely covers an upper end of the cannula, to a second configuration, in which the upper end of the cannula is exposed, due to the action of external thrust. The pen needle is configured to move from the second configuration to an irreversible third configuration, in which the shield entirely covers the upper end of the cannula, due to the action of thrust exerted by the thrust element.

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device. The cap assembly comprises: a cap body arranged to be mounted to a proximal end of a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel. The gripping member is radially flexible and has a first leg, a second leg, and a connecting portion extending between the first leg and the second leg. The first leg and the second leg each has a proximal portion that is radially flexible and extends distally from the connecting portion. Each proximal portion has an inclined section extending radially inwards in an axial direction away from the connecting portion.

Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end, operate the syringe to supply the dose of medicament, and retract the syringe with the needle after delivering the medicament. An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: A self-retracting syringe has an injection assembly and a retraction assembly. The injection assembly has a housing, a spring rest, and a spring that is restrained initially in compression between the housing and the spring rest. A plunger rod is disposed inside the coil of the spring. A coupler in contact with the spring rest and the plunger rod releasably couples the plunger rod to the spring rest. When a latch is released, the plunger rod moves distally to urge a seal forward, which seal movement causes a hypodermic needle to extend and a medicament to be expelled through the hypodermic needle. A retraction assembly returns the hypodermic needle into the syringe body after the medicament is expelled. Embodiments of retraction assembly provide a port through which fluid may be introduced into the syringe through said hypodermic needle. Methods for filling the syringe are also described.

Abstract: An autoinjector comprising a body (1) that is adapted to receive a reservoir (S), said reservoir (S) containing fluid and including a piston (P) and a needle (A), such as a pre-filled syringe, said autoinjector further comprising an actuator sleeve (10) that is movable relative to said body (1) between projecting positions in which said actuator sleeve (10) projects out from said body (1) at least in part, and an actuated position in which said actuator sleeve (10) is moved axially into said body (1), said actuator sleeve (10) being in a first projecting position before actuation of the autoinjector, and in a second projecting position after actuation of the autoinjector; said actuator sleeve (10) being urged towards said projecting positions by a spring (9), said autoinjector including a removable cap (20) that is fastened to said body (1) before the autoinjector is used, said removable cap (20), when it is fastened to said body (1), moving said actuator sleeve (10) axially relative to said first projecting

Abstract: An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier includes two identical parts that are discrete from one another and interlock with one another. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Abstract: An injection device includes a product container having an injection needle, a needle protection cap detachably secured to the product container surrounds the injection needle and seals same in a sterile manner. A cap is connected to the needle protection cap, via a remover element having an engaging element, in such a way that the removal of the cap from the injection device brings about the removal of the needle protection cap from the product container, where the engaging element is in an engaging position in relation to the needle protection cap, where in the engaging position, a section of the needle protection cap is arranged distally in line with the engaging element, characterized in that the cap and the engaging element are coupled in such a way that the cap is or can be moved relative to the engaging element during the removal from the injection device.

Abstract: A sample consumable that carries a microvolume of sample to a sample loader. The consumable is precisely aligned utilizing a double-alignment feature to the loader. The loader is based on a crank-slider geometry and allows for simple, one-handed operation for the user. Overall, the consumable and sample loader increase reproducibility of in-line sample loading and offers ease-of-use.

Abstract: The present disclosure relates to an injection needle assembly for use in a medicament delivery device. The injection needle assembly comprises an injection needle holder, an injection needle fixed to said injection needle holder, the injection needle having a proximal end and a distal end, and a sealing assembly for sealing the distal end of the injection needle. The sealing assembly comprises a spacer element surrounding the distal end of the injection needle and a sealing membrane for sealing the distal end of the injection needle.