Abstract: The invention relates to a safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly having: an attachment ring fixed to the tip of the container and a safety device to cover at least the distal end of the needle, the safety device attached to the attachment ring. The safety assembly has an attachment ring having an inner ring and an outer ring to be snapped onto each other, the inner ring having an inner recess for applying glue between the inner ring and the tip, and the inner ring and outer ring having mutually engaging elements preventing any rotation of the outer ring relative to the inner ring.

Abstract: An at least partly implantable system for injecting a substance into a patient's body. The system comprises at least one flexibly bendable infusion needle with a tip end of each of said at least one infusion needle arranged in at least one first housing for penetrating the first housing's outer wall in at least one penetration area and having the respective other end arranged in at least one second housing, the first and second housings being adapted for implantation inside the patient's body, wherein the at least one second housing is provided for implantation inside the patient's body remote from the at least one first housing and wherein the injection needle is sufficiently long to bridge the distance from the at least one second housing for remote implantation to the at least one first housing and further through the first housing up to the outer wall of the first housing.

Abstract: A medicament delivery device (100) for delivery of medicament from a container (12) into an injection site through a cannula (16). The device comprises a chassis (106), a drive mechanism (400) for driving a piston member (22) along a container axis (A) to expel the medicament through the cannula (16), and a carriage (200) for retaining the container (12), the cannula (16) and the drive mechanism (400). An insertion mechanism (70, 120, 130, 504) is provided for moving the carriage (200) in an insertion direction (H) relative to the chassis (106), and a cannula bending mechanism (300) is provided for bending the cannula (16) about a bending axis (B) to substantially align at least an end part of the cannula (16) with the insertion direction (H) prior to movement of the carriage (200) in the insertion direction (H).

Abstract: A medical injection device for supporting a medical container, the medical container comprising a barrel adapted to contain a composition and a needle extending from a distal end of the barrel, wherein the medical injection device comprises: a body configured to receive at least a part of the medical container, a plunger axially movable relative to the body along an axis of the body, needle cover movable relative to the body along the axis, the needle cover being configured to move successively between storage position wherein the needle cover covers the needle, an injection position wherein the needle cover exposes at least partially the needle, a safety position wherein the needle cover covers the needle and is prevented from moving back to the injection position.

Abstract: A needle end and a safety syringe are provided, belonging to technical field of medical instruments. The safety syringe includes an injection end, a liquid storage device, and a base. The injection end includes a needle base, an injection needle, and a needle guard assembly. The injection needle is fixed to the needle base. The needle guard assembly is connected to the needle base. The needle guard assembly includes a protective casing and a spring, wherein a first terminal of the spring is connected to the needle base and a second terminal of the spring is connected to the protective casing. The liquid storage device includes a liquid storage container and a liquid storage sleeve. The liquid storage is sleeved on an outer surface the liquid storage container, wherein the liquid storage container is detachably connected to the injection end. The base is detachably connected to the liquid storage device.

Abstract: A discharger for discharging a predetermined amount of fluid from a separate container including a discharge section defining a longitudinal axis and having a proximal end and a distal end and having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section. The discharger further includes an intermediate section including a distal portion cooperating with the proximal end of the discharge section and a proximal portion defining a receiving space which is adapted to be loaded with the separate container holding an amount of fluid to be discharged by the discharger. The distal portion and the proximal portion are formed in one piece and are interconnected by a breakable section.

Abstract: A nicotine powder delivery system includes an inhaler article and a nicotine powder capsule disposed within the inhaler article. The nicotine powder capsule rotates about a longitudinal axis when air flows through the inhaler article.

Abstract: Disclosed is an injection device for receiving a syringe therein and for delivering a dose of medicament from the syringe, the injection device including: an insertion driver configured to drive the syringe forwards within the injection device for inserting a needle of the syringe into an injection site; an interlock mechanism configured to retain the insertion driver in a primed state and, when actuated, to allow the insertion driver to drive the syringe forwards; and an interlock actuator moveable between a stowed position and an operable position and configured on movement from the stowed position to the operable position to couple to an actuation system such that movement from the operable position back towards the stowed position actuates the interlock mechanism.

Abstract: A feedback mechanism for an injection device that is configured to deliver a medicament to a user is described. The feedback mechanism comprises a piston and a fluid chamber, and the piston is adapted to move into the fluid chamber during use of the injection device. The feedback mechanism also has a damper that is arranged to damp movement of the piston, and an indicator that is arranged to provide feedback to the user after the piston has moved a pre-determined distance into the fluid chamber.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. The cartridge includes a vacuum bellows that surrounds the needle when the bellows is in an extended configuration. The vacuum bellows is compressible to expose the needle and generates a vacuum condition within the bellows when the bellows is extended from a compressed configuration to the extended configuration. The needle may be a dual-lumen plastic needle.

Abstract: A safety pen needle includes: a main body, a cannula fixed to the main body and at least partially projecting out of the main body, a lock element placed inside the main body, a thrust element placed inside the main body, and a shield movable relative to the main body while remaining at least partially inserted within the main body. The pen needle is configured to move from a first configuration, in which the shield entirely covers an upper end of the cannula, to a second configuration, in which the upper end of the cannula is exposed, due to the action of external thrust. The pen needle is configured to move from the second configuration to an irreversible third configuration, in which the shield entirely covers the upper end of the cannula, due to the action of thrust exerted by the thrust element.

Abstract: The present invention suppresses the amount of fluid pushed out from an injection needle when confirming whether air has been pushed out of the injection needle. Provided is a syringe that comprises: a cylinder 20; an injection needle 22; a needle base 24; an injection needle cover 26; and a plunger rod 28. The needle base 24 communicates between the inside of the cylinder 20 and the inside of the injection needle 22. The injection needle cover 26, when extended from a folded state, surrounds the injection needle 22. The injection needle cover 26 comprises an injection needle surrounding part. The injection needle surrounding part has at least one cutout 130 in a section facing the needle base 24 and covering the needle base, such that the needle base 24 can be identified from the outside.

Abstract: A self-retracting syringe has an injection assembly and a retraction assembly. The injection assembly has a housing, a spring rest, and a spring that is restrained initially in compression between the housing and the spring rest. A plunger rod is disposed inside the coil of the spring. A coupler in contact with the spring rest and the plunger rod releasably couples the plunger rod to the spring rest. When a latch is released, the plunger rod moves distally to urge a seal forward, which seal movement causes a hypodermic needle to extend and a medicament to be expelled through the hypodermic needle. A retraction assembly returns the hypodermic needle into the syringe body after the medicament is expelled. Embodiments of retraction assembly provide a port through which fluid may be introduced into the syringe through said hypodermic needle. Methods for filling the syringe are also described.

Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end, operate the syringe to supply the dose of medicament, and retract the syringe with the needle after delivering the medicament. An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device. The cap assembly comprises: a cap body arranged to be mounted to a proximal end of a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel. The gripping member is radially flexible and has a first leg, a second leg, and a connecting portion extending between the first leg and the second leg. The first leg and the second leg each has a proximal portion that is radially flexible and extends distally from the connecting portion. Each proximal portion has an inclined section extending radially inwards in an axial direction away from the connecting portion.

Abstract: An autoinjector comprising a body (1) that is adapted to receive a reservoir (S), said reservoir (S) containing fluid and including a piston (P) and a needle (A), such as a pre-filled syringe, said autoinjector further comprising an actuator sleeve (10) that is movable relative to said body (1) between projecting positions in which said actuator sleeve (10) projects out from said body (1) at least in part, and an actuated position in which said actuator sleeve (10) is moved axially into said body (1), said actuator sleeve (10) being in a first projecting position before actuation of the autoinjector, and in a second projecting position after actuation of the autoinjector; said actuator sleeve (10) being urged towards said projecting positions by a spring (9), said autoinjector including a removable cap (20) that is fastened to said body (1) before the autoinjector is used, said removable cap (20), when it is fastened to said body (1), moving said actuator sleeve (10) axially relative to said first projecting

Abstract: An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier includes two identical parts that are discrete from one another and interlock with one another. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Abstract: An injection device includes a product container having an injection needle, a needle protection cap detachably secured to the product container surrounds the injection needle and seals same in a sterile manner. A cap is connected to the needle protection cap, via a remover element having an engaging element, in such a way that the removal of the cap from the injection device brings about the removal of the needle protection cap from the product container, where the engaging element is in an engaging position in relation to the needle protection cap, where in the engaging position, a section of the needle protection cap is arranged distally in line with the engaging element, characterized in that the cap and the engaging element are coupled in such a way that the cap is or can be moved relative to the engaging element during the removal from the injection device.

Abstract: A sample consumable that carries a microvolume of sample to a sample loader. The consumable is precisely aligned utilizing a double-alignment feature to the loader. The loader is based on a crank-slider geometry and allows for simple, one-handed operation for the user. Overall, the consumable and sample loader increase reproducibility of in-line sample loading and offers ease-of-use.

Abstract: The present disclosure relates to an injection needle assembly for use in a medicament delivery device. The injection needle assembly comprises an injection needle holder, an injection needle fixed to said injection needle holder, the injection needle having a proximal end and a distal end, and a sealing assembly for sealing the distal end of the injection needle. The sealing assembly comprises a spacer element surrounding the distal end of the injection needle and a sealing membrane for sealing the distal end of the injection needle.

Abstract: A medicament delivery device (100; 300; 400) comprises a chassis (124), a drive element (166) for driving a stopper (22) to expel the medicament through a cannula (144). A carrier (126) is arranged for movement with respect to the chassis (124). Insertion means (130, 202) biases the carrier (126) in an insertion direction. A control part (132) is biased for rotation with respect to the carrier (126). A locking element (176) prevents rotation of the control part (132) in an initial state. The locking element (176) is coupled to the drive element (166) such that the control part (132) is released for rotation when the drive element (166) reaches an activation position during a delivery stroke. Rotation of the control part (132) through a predetermined angle causes decoupling of the insertion means (130, 202) from the carrier (126) to allow movement of the carrier (126) in a retraction direction after the end of the delivery stroke.

Abstract: A method includes protecting an entire length of a needle of a needle-based device in a first state of disuse thereof with a needle cap, encompassing, by a needle shield, the entire length of the needle and at least a partial length of the needle cap in the first state of disuse, and encompassing an entire protruding length of the needle cap outside the needle shield within a safety cap and securing the safety cap onto an outer surface of the needle shield such that the needle and the needle cap are completely protected and covered during the first state of disuse. Following removing the safety cap along with the needle cap from the needle shield, the method also includes retracting the needle shield to cause the needle to emerge out of the needle shield to prepare the needle-based device for a second state of use thereof.

Abstract: The present invention improves the feeling in use when a finger is hooked on a finger grip. This syringe is provided with a cylinder 22, a syringe needle 24, a finger grip 30, and a plunger rod 32. The finger grip 30 is provided with a cylindrical portion and a pair of finger hook portions. The finger hook portion has an inclined curved surface 70 and an end-side curved surface 72. The inclined curved surface 70 is disposed on a side, of a side surface of the finger hook portion, connected to the cylinder 22. In the inclined curved surface 70, the inclination of a base-side region with respect to the center axis of the cylindrical portion is gentler than the inclination of an end-side region with respect to the center axis of the cylindrical portion. The end-side curved surface 72 is disposed at the boundary between the end of the finger hook portion and the inclined curved surface 70. The end-side curved surface 72 extends along the boundary.

Abstract: A plunger configured as described herein provides geometry optimizations to minimize friction magnitude and variability during use by maintaining low deformation under large extrusion forces. More specifically, plunger embodiments described herein minimize a contact area between the plunger and a syringe or chamber, while also maintaining high contract pressures to maintain container closure integrity. Moreover, the plunger embodiments are configured to have minimal or no increase in the contact area under high loads associated with the delivery of viscous products.

Abstract: A method includes protecting an entire length of a needle of a needle-based device protruding from a needle mount coupled to a body thereof based on providing a needle shield configured to completely encompass the entire protruding length of the needle in a first state of disuse of the needle-based device, and retracting the needle shield in a first direction toward the body to cause the needle to emerge out of the needle shield to prepare the needle-based device for a second state of use. The method also includes transitioning the needle-based device back to the first state of disuse in accordance with a force applied in a second direction, securedly maintaining the needle shield in the first state of disuse, and locking the needle shield with a lock button formed on the needle shield or external thereto in the first state of disuse of the needle-based device.

Abstract: The invention relates to a safe support device for a syringe, said support comprising a support sheath for the body of a syringe, and safety means which comprise an inner sheath suitable for sliding relative to said support sheath between a waiting retracted position, in which said inner sheath is substantially retracted inside said support sheath, and an active protection position, in which said inner sheath projects from said support sheath. The inner sheath has a free end portion formed by a flexible end-piece. The invention also relates to an assembly comprising such a safe support device and a syringe having a body, a piston and a needle disposed at one end of said body.

Abstract: A needle shield remover is presented having a generally tubular body with a longitudinal extension and a number of grip elements arranged at a distal area of the body, where the grip elements extend radially inwards from a circumference of the body. At least one longitudinally extending cut-out in the body and adjacent to the grip elements engage an outer surface of a needle shield when the needle shield remover is pushed onto the needle shield, where the at least one cut-out enables a generally radial outwardly bias of the grip elements during the pushing action to facilitate mounting of the needle shield remover on the needle shield.

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

Abstract: The present invention relates to an automatic injection training device (10) comprising an elongated housing (12) having a distal end (14) and an opposite proximal end (16) and extending along a longitudinally axis (L); a tubular demo container (128) axially and rotationally fixed relative to the elongated housing (12) and having a tubular wall (140) extending along the longitudinally axis (L); a reloadable plunger assembly (104) comprising a plunger rod (106) which is movable in the demo container (128) between a first and a second position and a first energy accumulating element (110) configured to move the plunger rod (106) from the first to the second position; an actuation assembly (42) configured to hold the plunger rod (106) in the first position and to release the plunger rod (106) from the first position.

Abstract: A safety needle device is disclosed comprising a hub, needle cannula, housing, tether, retractable sleeve, locking member and spring element. The tether is slidably disposed in the housing, the tether having a slot with an enlarged first guide path and a narrowed second guide path extending distally from the enlarged first guide path. The retractable sleeve is configured to move between an initial position, retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula.

Abstract: The present invention relates to a medicament delivery device comprising a housing (16, 18), arranged to accommodate a medicament container (26); a power unit (64) arranged inside said housing, said power unit comprising a plunger rod (112), a drive spring (114) operably arranged to act on the plunger rod (112) and, which is, upon activation, operably arranged to act on said medicament container (26), an actuator (90) comprising holding elements (94, 100), capable of releasably holding said plunger rod (1112) with said drive spring (114) in a tensioned state, and an actuator sleeve (76) operably connected to said actuator (90) for releasably locking said holding elements (94, 100) in a holding state; said medicament delivery device further comprising a medicament delivery member guard (34) slidably movable in said housing (16, 18) and arranged to act on said actuator sleeve (76) for setting said holding elements (94, 100) with said actuator sleeve (76) in a first activation state; an activator unit (124) arra

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device, having a cap containing a tubular body provided with a distal opening, the cap being configured to be mounted to a proximal end of a medicament delivery device, a tubular remover configured to be received in the distal opening of the cap, the remover having flexible radially inwards extending grippers configured to engage with a delivery member shield, and a tubular remover insert configured to be received by the remover and configured to be fixedly attached to the cap to prevent axial displacement of the remover insert relative to the cap, wherein the remover is axially displaceable relative to the cap and relative to the remover insert, from a first position in which the grippers are pressed radially outwards by an outer surface of the remover insert, to a second position located distally relative to the first position, in which second position the grippers are arranged distally beyond the outer surface of the remover insert,

Abstract: A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a device shield interconnected to a lock collar with flexible member and biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. As the device shield moves proximally, rotation arms of the lock collar interact with angled cutouts in the device shield, causing the device shield to rotate relative to the lock collar and disengaging one or more keys on the device shield from one or more keyways in the lock collar triggering the device shield to move from a first configuration in which the device shield is retractable to expose a syringe sharp to a second configuration in which the device shield is fixedly positioned to cover the syringe sharp.

Abstract: A cartridge (100) for packaging a medicament and being suitable for use with multiple different types of dosing device is described, together with dosing devices and adaptors for dosing devices. The cartridge includes a generally tubular body (102) having an interior cavity (104), a closure member (106) disposed at a distal end of the body and comprising a sealing element (128), a piston member (108) disposed in the cavity to contain the medicament between the piston member and the sealing element (128), a coupling element (114) disposed at the distal end of the body for coupling the cartridge to a dosing device (200) or to an adaptor for a dosing device, and a seal arrangement (126, 129) for receiving a sealing element release member (214) of the dosing device or adaptor.

Abstract: A protective dental needle includes a sheath having a cylindrical body with a channel along the cylindrical body. A needle assembly includes a hypodermic needle extending through a hub. The needle assembly is retained within the sheath and movable within the sheath between a retracted position and an extended position. A needle cap is positioned external to the sheath. The needle cap includes a plurality of longitudinal ribs that extend from an interior surface of the needle cap.

Abstract: The present invention relates to a needle shield assembly for a syringe (10), comprising an inner needle shield (16) which is flexible and designed to enclose a major part of a hollow injection needle (18) of said syringe; an outer needle shield (20) which is rigid and designed to enclose a major part of said inner needle shield (16), which outer needle shield (20) is arranged with a number of passages (22) for allowing sterilizing agents to reach said injection needle (18) during a sterilization process. The invention is characterised in that said needle shield assembly further comprises a cover element (24; 36; 46) arranged adjacent said passages (22) such as to prevent the interior of said injection needle (18) from being exposed to oxygen via said passages (22) of said outer needle shield (20) after said sterilization process.

Abstract: A distribution assembly having a syringe having a body with a tip supporting a needle having a bevel, and a removable syringe needle protection device. The protection device has a flexible cap defining an inside cavity defined by a side wall and by a distal solid end wall, and when in the protection position, receiving the bevel of the needle in airtight manner. The side wall includes an annular bead provided with at least one slot extending across the bead in a longitudinal direction, the bead, when in the protection position, co-operating in airtight manner with the tip of the syringe. The cavity of the cap is dimensioned so that when the protection device is removed from the syringe, the cavity is connected to the atmosphere via the slot before the bevel of the needle becomes connected to the cavity.

Abstract: The present invention relates to an autoinjector device (10) for use in combination with a syringe (30), said syringe comprising a movable plunger; a needle; and a tubular needle shield (34). The claimed autoinjector device (10) comprises: an elongated housing having a proximal (11) and a distal end (12); a drive mechanism; a syringe holder (40) in order to support the fragile syringe and to prevent damage to the syringe. The invention furthermore relates to a method for assembly of the autoinjector device according to the invention.

Abstract: An example system for administrating a liquid medication includes a syringe assembly including a barrel portion containing liquid medication, a plunger portion sealingly engaged with the barrel portion to form a chamber for expelling the liquid medication from the barrel portion, and a needle. A ring is positioned about the plunger portion of the syringe assembly, wherein the ring limits movement of the plunger portion in an axial direction as the plunger portion is moved in the axial direction to administer a first dose of the liquid medication. The ring is configured to be modified to allow the plunger to move further in the axial direction to administer a second dose of the liquid medication.

Abstract: An insulin injection needle with needle tip protection has a needle body, needle base, main cover and outer sheath. The main cover is provided with the trigger tube, front casing and spring. The trigger tube is used to protect the injection section of needle body before use and the front casing is used to protect the injection section of needle body after use. Before use, the trigger tube extends out of the main cover and is in the state of protecting the needle, and the front casing is in the main cover; after, the trigger tube is in the main cover and the front casing extends out of the main cover and protects the needle. The unlocking of trigger tube and front casing correlate with injection readiness and the tail cover and needle base trigger the unlocking of trigger tube and front casing during the installation.

Abstract: The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) containing a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting button (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed.

Abstract: A fluid delivery device comprises a housing having a base including a bottom surface; a locking assembly including a cartridge receiver configured to receive a cartridge, the cartridge having a fluid reservoir and a septum configured to be generally perpendicular to the bottom surface when the cartridge is engaged with the cartridge receiver; and a needle assembly having a needle, the needle having a delivery end, a fluid coupling end, and a central portion located between the delivery end and the fluid coupling end, the needle assembly configured to move in laterally relative to the base to a first position and vertically relative to the base to a second position. The locking assembly prevents the needle assembly from moving to one or both of the first and second positions unless the cartridge is engaged with the cartridge receiver.

Abstract: An injection apparatus includes a base, an anesthetic holder, one or more vibration motors, and a hollow cylinder. The base includes a bottom surface for placement against a patient's skin, wherein the base includes one or more apertures. The anesthetic holder extends from the base and retains an anesthetic, wherein the holder is in fluid communication with the one or more apertures located on the base. The one or more vibration motors are affixed to the holder. The hollow cylinder includes a first end and a second end, wherein the first end is configured to receive an injecting pen and the second end is located adjacent to the base and is configured to allow the injecting pen to contact the patient's skin.

Abstract: A syringe assembly for use as a pre-filled syringe is disclosed. The syringe assembly includes a syringe barrel defining a chamber and having a stopper disposed therein. A plunger rod includes an inner member engaged with a portion of the stopper and an outer member adapted for rotational advancement with respect to the inner member to axially displace the outer member with respect to the inner member. The plunger rod is transitionable from a collapsed position in which a portion of the inner member is nested within the outer member, to an extended position in which the same portion of the inner member extends outside the outer member. The inner member includes a radial extension and the outer member defines a helical track adapted to receive the radial extension therein.

Abstract: A drug delivery device includes an inner body adapted to receive a pre-filled syringe with an injection needle, one or more flexible arms on the inner body extending in a distal direction, and one or more support members slidably arranged to operatively outwardly support the flexible arms. The flexible arms have respective inwardly directed protrusions adapted to engage a neck of the syringe. When the support member is in a distal position, it does not support the flexible arms. When the support member is in a proximal position, the support member supports the flexible arms and prevents them from being outwardly deflected.

Abstract: A drug delivery device comprises a housing and a mechanical assembly, which is at least partially accommodated in the housing. The mechanical assembly comprises a predetermined breaking member, which is configured to be damaged when forcefully separated from the housing.

Abstract: A protective device, for covering a needle tip of a needle of a medical instrument after puncturing of a puncture object by the needle, includes an inner cylinder, an outer cylinder, and a spring. The outer cylinder receives a cam structure of the inner cylinder and has a guide passage structure that includes one or more guide passages. The outer cylinder is provided with a lateral top part and a distal-end inclined edge part as resistance force generating parts for causing the inner cylinder to generate a resistance force at a puncture position or in the vicinity of the puncture position.

Abstract: Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.

Abstract: A medicament injection device is provided. The device includes a main body configured to receive a medicament cartridge sealed with a penetrable holder. The device can further include a needle holder holding a needle, a needle sleeve arranged to be axially movable with respect to the main body, and a retainer coupled to the needle holder and to the needle sleeve. The retainer can be axially movable with respect to the main body along the main axis of the device. Upon displacement of the needle sleeve and the retainer by a predefined distance towards a proximal end of the main body, the needle holder and the needle can be displaced axially towards the proximal end of the main body and decouple from the retainer. The needle sleeve can be configured to disengage from the needle holder upon displacement of the needle sleeve.

Abstract: An automatic injection device for delivering a dose from a medicine containing syringe includes a housing for containing the syringe, a force applicator for applying a force to eject medicine from the syringe, a trigger coupled to the force applicator for releasing the force applicator to cause an injection, a boot covering a needle attached to the syringe to protect and maintain sterility of the needle, and a mechanical interlock. The mechanical interlock prevents actuation of the trigger prior to removal of the boot. When the boot is removed, the mechanical interlock allows for actuation of the trigger.