Abstract: A medicament delivery device (100; 300; 400) comprises a chassis (124), a drive element (166) for driving a stopper (22) to expel the medicament through a cannula (144). A carrier (126) is arranged for movement with respect to the chassis (124). Insertion means (130, 202) biases the carrier (126) in an insertion direction. A control part (132) is biased for rotation with respect to the carrier (126). A locking element (176) prevents rotation of the control part (132) in an initial state. The locking element (176) is coupled to the drive element (166) such that the control part (132) is released for rotation when the drive element (166) reaches an activation position during a delivery stroke. Rotation of the control part (132) through a predetermined angle causes decoupling of the insertion means (130, 202) from the carrier (126) to allow movement of the carrier (126) in a retraction direction after the end of the delivery stroke.

Abstract: A method includes protecting an entire length of a needle of a needle-based device in a first state of disuse thereof with a needle cap, encompassing, by a needle shield, the entire length of the needle and at least a partial length of the needle cap in the first state of disuse, and encompassing an entire protruding length of the needle cap outside the needle shield within a safety cap and securing the safety cap onto an outer surface of the needle shield such that the needle and the needle cap are completely protected and covered during the first state of disuse. Following removing the safety cap along with the needle cap from the needle shield, the method also includes retracting the needle shield to cause the needle to emerge out of the needle shield to prepare the needle-based device for a second state of use thereof.

Abstract: The present invention improves the feeling in use when a finger is hooked on a finger grip. This syringe is provided with a cylinder 22, a syringe needle 24, a finger grip 30, and a plunger rod 32. The finger grip 30 is provided with a cylindrical portion and a pair of finger hook portions. The finger hook portion has an inclined curved surface 70 and an end-side curved surface 72. The inclined curved surface 70 is disposed on a side, of a side surface of the finger hook portion, connected to the cylinder 22. In the inclined curved surface 70, the inclination of a base-side region with respect to the center axis of the cylindrical portion is gentler than the inclination of an end-side region with respect to the center axis of the cylindrical portion. The end-side curved surface 72 is disposed at the boundary between the end of the finger hook portion and the inclined curved surface 70. The end-side curved surface 72 extends along the boundary.

Abstract: A plunger configured as described herein provides geometry optimizations to minimize friction magnitude and variability during use by maintaining low deformation under large extrusion forces. More specifically, plunger embodiments described herein minimize a contact area between the plunger and a syringe or chamber, while also maintaining high contract pressures to maintain container closure integrity. Moreover, the plunger embodiments are configured to have minimal or no increase in the contact area under high loads associated with the delivery of viscous products.

Abstract: A method includes protecting an entire length of a needle of a needle-based device protruding from a needle mount coupled to a body thereof based on providing a needle shield configured to completely encompass the entire protruding length of the needle in a first state of disuse of the needle-based device, and retracting the needle shield in a first direction toward the body to cause the needle to emerge out of the needle shield to prepare the needle-based device for a second state of use. The method also includes transitioning the needle-based device back to the first state of disuse in accordance with a force applied in a second direction, securedly maintaining the needle shield in the first state of disuse, and locking the needle shield with a lock button formed on the needle shield or external thereto in the first state of disuse of the needle-based device.

Abstract: The invention relates to a safe support device for a syringe, said support comprising a support sheath for the body of a syringe, and safety means which comprise an inner sheath suitable for sliding relative to said support sheath between a waiting retracted position, in which said inner sheath is substantially retracted inside said support sheath, and an active protection position, in which said inner sheath projects from said support sheath. The inner sheath has a free end portion formed by a flexible end-piece. The invention also relates to an assembly comprising such a safe support device and a syringe having a body, a piston and a needle disposed at one end of said body.

Abstract: A needle shield remover is presented having a generally tubular body with a longitudinal extension and a number of grip elements arranged at a distal area of the body, where the grip elements extend radially inwards from a circumference of the body. At least one longitudinally extending cut-out in the body and adjacent to the grip elements engage an outer surface of a needle shield when the needle shield remover is pushed onto the needle shield, where the at least one cut-out enables a generally radial outwardly bias of the grip elements during the pushing action to facilitate mounting of the needle shield remover on the needle shield.

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

Abstract: The present invention relates to an automatic injection training device (10) comprising an elongated housing (12) having a distal end (14) and an opposite proximal end (16) and extending along a longitudinally axis (L); a tubular demo container (128) axially and rotationally fixed relative to the elongated housing (12) and having a tubular wall (140) extending along the longitudinally axis (L); a reloadable plunger assembly (104) comprising a plunger rod (106) which is movable in the demo container (128) between a first and a second position and a first energy accumulating element (110) configured to move the plunger rod (106) from the first to the second position; an actuation assembly (42) configured to hold the plunger rod (106) in the first position and to release the plunger rod (106) from the first position.

Abstract: A safety needle device is disclosed comprising a hub, needle cannula, housing, tether, retractable sleeve, locking member and spring element. The tether is slidably disposed in the housing, the tether having a slot with an enlarged first guide path and a narrowed second guide path extending distally from the enlarged first guide path. The retractable sleeve is configured to move between an initial position, retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula.

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device, having a cap containing a tubular body provided with a distal opening, the cap being configured to be mounted to a proximal end of a medicament delivery device, a tubular remover configured to be received in the distal opening of the cap, the remover having flexible radially inwards extending grippers configured to engage with a delivery member shield, and a tubular remover insert configured to be received by the remover and configured to be fixedly attached to the cap to prevent axial displacement of the remover insert relative to the cap, wherein the remover is axially displaceable relative to the cap and relative to the remover insert, from a first position in which the grippers are pressed radially outwards by an outer surface of the remover insert, to a second position located distally relative to the first position, in which second position the grippers are arranged distally beyond the outer surface of the remover insert,

Abstract: The present invention relates to a medicament delivery device comprising a housing (16, 18), arranged to accommodate a medicament container (26); a power unit (64) arranged inside said housing, said power unit comprising a plunger rod (112), a drive spring (114) operably arranged to act on the plunger rod (112) and, which is, upon activation, operably arranged to act on said medicament container (26), an actuator (90) comprising holding elements (94, 100), capable of releasably holding said plunger rod (1112) with said drive spring (114) in a tensioned state, and an actuator sleeve (76) operably connected to said actuator (90) for releasably locking said holding elements (94, 100) in a holding state; said medicament delivery device further comprising a medicament delivery member guard (34) slidably movable in said housing (16, 18) and arranged to act on said actuator sleeve (76) for setting said holding elements (94, 100) with said actuator sleeve (76) in a first activation state; an activator unit (124) arra

Abstract: A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a device shield interconnected to a lock collar with flexible member and biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. As the device shield moves proximally, rotation arms of the lock collar interact with angled cutouts in the device shield, causing the device shield to rotate relative to the lock collar and disengaging one or more keys on the device shield from one or more keyways in the lock collar triggering the device shield to move from a first configuration in which the device shield is retractable to expose a syringe sharp to a second configuration in which the device shield is fixedly positioned to cover the syringe sharp.

Abstract: A cartridge (100) for packaging a medicament and being suitable for use with multiple different types of dosing device is described, together with dosing devices and adaptors for dosing devices. The cartridge includes a generally tubular body (102) having an interior cavity (104), a closure member (106) disposed at a distal end of the body and comprising a sealing element (128), a piston member (108) disposed in the cavity to contain the medicament between the piston member and the sealing element (128), a coupling element (114) disposed at the distal end of the body for coupling the cartridge to a dosing device (200) or to an adaptor for a dosing device, and a seal arrangement (126, 129) for receiving a sealing element release member (214) of the dosing device or adaptor.

Abstract: A protective dental needle includes a sheath having a cylindrical body with a channel along the cylindrical body. A needle assembly includes a hypodermic needle extending through a hub. The needle assembly is retained within the sheath and movable within the sheath between a retracted position and an extended position. A needle cap is positioned external to the sheath. The needle cap includes a plurality of longitudinal ribs that extend from an interior surface of the needle cap.

Abstract: The present invention relates to a needle shield assembly for a syringe (10), comprising an inner needle shield (16) which is flexible and designed to enclose a major part of a hollow injection needle (18) of said syringe; an outer needle shield (20) which is rigid and designed to enclose a major part of said inner needle shield (16), which outer needle shield (20) is arranged with a number of passages (22) for allowing sterilizing agents to reach said injection needle (18) during a sterilization process. The invention is characterised in that said needle shield assembly further comprises a cover element (24; 36; 46) arranged adjacent said passages (22) such as to prevent the interior of said injection needle (18) from being exposed to oxygen via said passages (22) of said outer needle shield (20) after said sterilization process.

Abstract: A distribution assembly having a syringe having a body with a tip supporting a needle having a bevel, and a removable syringe needle protection device. The protection device has a flexible cap defining an inside cavity defined by a side wall and by a distal solid end wall, and when in the protection position, receiving the bevel of the needle in airtight manner. The side wall includes an annular bead provided with at least one slot extending across the bead in a longitudinal direction, the bead, when in the protection position, co-operating in airtight manner with the tip of the syringe. The cavity of the cap is dimensioned so that when the protection device is removed from the syringe, the cavity is connected to the atmosphere via the slot before the bevel of the needle becomes connected to the cavity.

Abstract: The present invention relates to an autoinjector device (10) for use in combination with a syringe (30), said syringe comprising a movable plunger; a needle; and a tubular needle shield (34). The claimed autoinjector device (10) comprises: an elongated housing having a proximal (11) and a distal end (12); a drive mechanism; a syringe holder (40) in order to support the fragile syringe and to prevent damage to the syringe. The invention furthermore relates to a method for assembly of the autoinjector device according to the invention.

Abstract: An example system for administrating a liquid medication includes a syringe assembly including a barrel portion containing liquid medication, a plunger portion sealingly engaged with the barrel portion to form a chamber for expelling the liquid medication from the barrel portion, and a needle. A ring is positioned about the plunger portion of the syringe assembly, wherein the ring limits movement of the plunger portion in an axial direction as the plunger portion is moved in the axial direction to administer a first dose of the liquid medication. The ring is configured to be modified to allow the plunger to move further in the axial direction to administer a second dose of the liquid medication.

Abstract: An insulin injection needle with needle tip protection has a needle body, needle base, main cover and outer sheath. The main cover is provided with the trigger tube, front casing and spring. The trigger tube is used to protect the injection section of needle body before use and the front casing is used to protect the injection section of needle body after use. Before use, the trigger tube extends out of the main cover and is in the state of protecting the needle, and the front casing is in the main cover; after, the trigger tube is in the main cover and the front casing extends out of the main cover and protects the needle. The unlocking of trigger tube and front casing correlate with injection readiness and the tail cover and needle base trigger the unlocking of trigger tube and front casing during the installation.

Abstract: The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) containing a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting button (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed.

Abstract: A fluid delivery device comprises a housing having a base including a bottom surface; a locking assembly including a cartridge receiver configured to receive a cartridge, the cartridge having a fluid reservoir and a septum configured to be generally perpendicular to the bottom surface when the cartridge is engaged with the cartridge receiver; and a needle assembly having a needle, the needle having a delivery end, a fluid coupling end, and a central portion located between the delivery end and the fluid coupling end, the needle assembly configured to move in laterally relative to the base to a first position and vertically relative to the base to a second position. The locking assembly prevents the needle assembly from moving to one or both of the first and second positions unless the cartridge is engaged with the cartridge receiver.

Abstract: An injection apparatus includes a base, an anesthetic holder, one or more vibration motors, and a hollow cylinder. The base includes a bottom surface for placement against a patient's skin, wherein the base includes one or more apertures. The anesthetic holder extends from the base and retains an anesthetic, wherein the holder is in fluid communication with the one or more apertures located on the base. The one or more vibration motors are affixed to the holder. The hollow cylinder includes a first end and a second end, wherein the first end is configured to receive an injecting pen and the second end is located adjacent to the base and is configured to allow the injecting pen to contact the patient's skin.

Abstract: A syringe assembly for use as a pre-filled syringe is disclosed. The syringe assembly includes a syringe barrel defining a chamber and having a stopper disposed therein. A plunger rod includes an inner member engaged with a portion of the stopper and an outer member adapted for rotational advancement with respect to the inner member to axially displace the outer member with respect to the inner member. The plunger rod is transitionable from a collapsed position in which a portion of the inner member is nested within the outer member, to an extended position in which the same portion of the inner member extends outside the outer member. The inner member includes a radial extension and the outer member defines a helical track adapted to receive the radial extension therein.

Abstract: A drug delivery device includes an inner body adapted to receive a pre-filled syringe with an injection needle, one or more flexible arms on the inner body extending in a distal direction, and one or more support members slidably arranged to operatively outwardly support the flexible arms. The flexible arms have respective inwardly directed protrusions adapted to engage a neck of the syringe. When the support member is in a distal position, it does not support the flexible arms. When the support member is in a proximal position, the support member supports the flexible arms and prevents them from being outwardly deflected.

Abstract: A drug delivery device comprises a housing and a mechanical assembly, which is at least partially accommodated in the housing. The mechanical assembly comprises a predetermined breaking member, which is configured to be damaged when forcefully separated from the housing.

Abstract: A protective device, for covering a needle tip of a needle of a medical instrument after puncturing of a puncture object by the needle, includes an inner cylinder, an outer cylinder, and a spring. The outer cylinder receives a cam structure of the inner cylinder and has a guide passage structure that includes one or more guide passages. The outer cylinder is provided with a lateral top part and a distal-end inclined edge part as resistance force generating parts for causing the inner cylinder to generate a resistance force at a puncture position or in the vicinity of the puncture position.

Abstract: Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.

Abstract: A medicament injection device is provided. The device includes a main body configured to receive a medicament cartridge sealed with a penetrable holder. The device can further include a needle holder holding a needle, a needle sleeve arranged to be axially movable with respect to the main body, and a retainer coupled to the needle holder and to the needle sleeve. The retainer can be axially movable with respect to the main body along the main axis of the device. Upon displacement of the needle sleeve and the retainer by a predefined distance towards a proximal end of the main body, the needle holder and the needle can be displaced axially towards the proximal end of the main body and decouple from the retainer. The needle sleeve can be configured to disengage from the needle holder upon displacement of the needle sleeve.

Abstract: A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments, and a fitment. The first compartment contains at least a first constintuent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.

Abstract: An automatic injection device for delivering a dose from a medicine containing syringe includes a housing for containing the syringe, a force applicator for applying a force to eject medicine from the syringe, a trigger coupled to the force applicator for releasing the force applicator to cause an injection, a boot covering a needle attached to the syringe to protect and maintain sterility of the needle, and a mechanical interlock. The mechanical interlock prevents actuation of the trigger prior to removal of the boot. When the boot is removed, the mechanical interlock allows for actuation of the trigger.

Abstract: A medical device comprises an elongate sheath defining a first lumen and comprising a distal portion and a flexible proximal portion. The medical device further comprises an elongate instrument slidably disposed at least partially within the first lumen. The elongate instrument comprises a flexible tubular proximal section and a rigid distal section defining a second lumen. The medical device further comprises an instrument handle coupled to a proximal end of the elongate instrument. The medical device further comprises a sheath handle coupled to a proximal end of the elongate sheath. The sheath handle is configured to at least partially receive the instrument handle. The medical device further comprises a holding mechanism coupled to the sheath handle. The holding mechanism is rotatable to engage the elongate instrument to maintain the rigid distal section of the elongate instrument in an extended position from the distal portion of the elongate sheath.

Abstract: A drug delivery device includes an outer body receiving a cartridge with a needle, a needle cap adapted to be coupled to the outer body and to cover the needle and a control mechanism for activating the drug delivery device. The control mechanism includes a control element received within the outer body and axially and/or rotationally movable relative to the outer body between an initial position, a first activating position, and a second activating position. The control element is coupled to the needle cap and to the cartridge, the needle cap is retained on the outer body when the control element is in the initial position, the needle cap is released from the outer body and the needle is covered by the outer body when the control element is in the first activating position, and the needle is exposed when the control element is in the second activating position.

Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.

Abstract: A safety needle device is disclosed having a hub, needle cannula, housing, tether, retractable sleeve, locking member and spring element. The tether is movably disposed in the housing, the tether having a slot with an enlarged first guide path and a narrowed second guide path extending distally from the enlarged first guide path. The retractable sleeve is configured to move from an initial position to partially expose a distal tip of the needle cannula, a retracted position to fully exposes the needle cannula, and an extended position to fully cover the distal tip of the needle cannula. The proximal movement of one or more protrusions on the retractable sleeve, rotates the tether to move the at least one or more protrusions from the enlarged first guide path of the tether to the narrowed second guide path of the tether, this rotation activating the device.

Abstract: Disclosed is a safety syringe capable of preventing needle-stick injuries, filtering foreign matters in a fluid, and preventing reuse thereof. The safety syringe includes: a safety needle part provided with a safety cap, the safety cap being configured to pop out by an elastic force of an elastic body connected thereto when the safety cap is unlatched and to be fixed while surrounding a needle tip; a filter part being configured such that a first end thereof is coupled with the safety needle part, and filtering fluid introduced or discharged through the needle; and a main body part being configured such that a first end thereof is coupled with the filter part, and having a barrel with a piston mounted therein, the piston being provided at a fore end thereof with an insertion part pushing out the fluid by being inserted into a luer of the syringe.

Abstract: The invention relates to a prefilled injection pen for apportioning multiple set doses of a liquid drug. The injection pen comprises a housing assembly with a removable cap rotatable coupled to the housing assembly such that the user has to rotate the removable cap upon mounting and dismounting the removable cap. Rotation of the removable cap initiates a process in which the proximal end of a needle cannula is first inserted into a cartridge permanently embedded in the housing assembly and thereafter moves the cartridge proximally to thereby pump a predetermined amount of the preservative containing liquid drug from the cartridge and into a cleaning chamber carried by an axially movable shield. The needle cannula is mounted in a needle hub which is arranged to follow rotation of the removable cap and guided helically in relation to the housing assembly such that the needle hub is moved proximally upon rotation of the removable cap.

Abstract: A syringe safety device is disclosed herein that comprises a shaft configured to support a barrel of a syringe, a guard configured to be disposed inside the shaft before the syringe is used and to extend outwardly from the shaft after the syringe is used, and a lock disposed between the guard and the shaft having a lock head disposed at a first end thereof, the lock head being disposed in a first aperture in the shaft before the syringe is used and in a second aperture in the shaft after the syringe has been used. A method of using the device also is described.

Abstract: A decorative medication holder may reduce or eliminate medication non-adherence and work with standard and/or non-standard medication containers. The medication holder may include a body portion having an opening to a medication retaining cavity adapted for receiving a medication, such as a bottle of pills. The body portion also may be decorated with a kid-friendly aesthetic design, such as a character, animal, or the like to engage a child's interest. In some embodiments, the body portion may include a substantially flat outer surface. Alternatively, the body portion also may include three-dimensional limbs or the like which may be rigid or posable. In some embodiments, a cover may be provided to close the opening and/or secure the medication in the cavity. Alternatively, or additionally, the cavity may include textured lining or the like to grip the medication in the cavity. Other embodiments also are described.

Abstract: An autoinjector includes a case having a rib, a needle shroud telescopically coupled to the case, a carrier slidably arranged in the case and adapted to hold a medicament container, and a collar rotatably and slidably disposed in the case and coupled to the needle shroud and the carrier. The needle shroud is movable between a first extended position, a retracted position and a locked second extended position. The carrier is movable from a first axial position to a second axial position relative to the case. The collar abuts the rib when the needle shroud is in the first extended position and the carrier is in the first axial position, and the collar disengages the rib when the needle shroud is in the retracted position and the carrier is in the second axial position.

Abstract: A fluid delivery injector comprises a syringe defining a barrel; a plunger and a hollow needle provided within the barrel adapted for linear movement parallel to a longitudinal axis with a distal tip of the needle contained within the syringe. A fluid retention reservoir is defined at least in the barrel and is in fluid communication with the needle when pressure is applied to the fluid in the reservoir and to the plunger for moving the needle out of the barrel. A spring may be provided for retracting the needle when pressure is released from the plunger.

Abstract: A needle device includes a catheter tube attached to a catheter hub, a needle attached to a needle hub, and a needle guard. The catheter hub has an interior cavity and a projection extending from an interior surface in the interior cavity. The needle projects through the catheter tube and has a needle tip extending out a distal end of the catheter tube in a ready position, a proximal end attached to a needle hub, and a shaft having a shaft diameter region, a reduced diameter region, and at least one transition region between the shaft diameter region and the reduced diameter region. The needle guard has a proximal wall and two arms extending distal the proximal wall. The two arms press against the shaft in the ready position and secure the needle tip in the protective position.

Abstract: A method for preparing a chitosan/heparinized graphene oxide composite multilayer film on the surface of a medical magnesium alloy comprises the following steps: firstly preparing negatively charged heparinized graphene oxide; then performing surface chemical treatment and self-assembly of 16-phosphonohexadecanoic acid molecules on the medical magnesium alloy; further covalently immobilizing chitosan on the surface of the magnesium alloy, thereby constructing a positively charged material surface; finally, alternately immersing the surface-modified magnesium alloy material in heparinized graphene oxide and a chitosan solution, and then fully adsorbing, and obtaining the chitosan/heparinized graphene oxide composite multilayer film after drying.

Abstract: Devices and methods for inserting an implant into skin or other tissue of a patient can include a hyaluronic thread coupled with an insertion device that can provide a supportive enclosure for the thread as it is injected into a patient's skin or other tissue. The device can include a cover member, a base, and a thread. The cover member can have a proximal portion, a closed distal portion, and an inner cavity extending from the proximal portion toward the closed distal portion. The thread can be positioned within the inner cavity and extend from the base toward the closed distal portion. The base can be removably coupled to the proximal portion of the cover member. In use, the cover member is insertable into a patient and separable from the base to expose the thread.

Abstract: There is provided a guide 200 for contacting an injection device 110 with a user; the guide 200 having a first end 210 adapted to engage a housing 112 of the injection device 110 and a second end 220 adapted to engage the surface of a user's skin, wherein the guide 200 permits movement of the housing 112 towards the user's skin.

Abstract: A pipetting device comprising a head and a nozzle with a longitudinal axis mounted to the head is disclosed. An actuator member is arranged around and partially covering the nozzle and coupled to the head or to the nozzle. The actuator member and the nozzle move with respect to each other along the longitudinal axis. A contact member is coupled to and arranged around and partially covering the actuator member. The contact member and the actuator member move with respect to each other. The contact member comprises a rim for contacting a container. The actuator member comprises a rim for opening a cap of the container when the contact member is in contact with the container. The actuator member and the contact member move with respect to each other creating a passage through the cap when the nozzle and the actuator member move with respect to each other.

Abstract: An autoinjector having a body (1) and an actuator sleeve (10) having a first projecting position before actuation and a second projecting position after actuation. The actuator sleeve or the body has a flexible tab (110) that deforms laterally when the actuator sleeve moves from its first projecting position to its actuated position, then from its actuated position to return to its second projecting position. The other of the actuator sleeve and the body has an initial zone (102), an intermediate zone (105), and a final reception zone (106) co-operating with the flexible tab in the first projecting position, actuated position, and second projecting position, respectively. The final reception zone is offset laterally from the initial zone. A deformable axial wall (1020) deforms allowing the flexible tab to pass from the initial zone to the intermediate zone and guides it from the intermediate zone to the final reception zone.

Abstract: A syringe having a bonded needle, comprising a syringe body, a needle protector comprising a flexible cap, an outer sleeve, which can move along a longitudinal axis between an extended position, in which it covers the needle, and a retracted position, in which it does not cover the needle, and a collar, which is mounted with a radial clearance around an end part of the syringe body and which comprises at least one pin engaged in a guide opening of the sleeve. A portion of the flexible cap fills the radial clearance between the end part of the syringe body and the collar when the cap is mounted on the syringe, such that the collar cannot rotate around the end part of the syringe body as long as the cap is mounted on the syringe.

Abstract: Container holder assembly for use in a medicament delivery device, comprising a tubular body elongated in an axial direction, said tubular body having a proximal end and an opposite distal end, and a retaining member releasably arranged to said tubular body for securing an elongated container placed inside the tubular body, wherein said retaining member comprises a resilient structure capable of exerting an axial force on said container in said tubular body for holding the container in a fixed position inside the tubular body and thereby avoiding displacement or breakage of the container and wherein a distal end of said container protrudes from a distal end of said tubular body.

Abstract: A device for a hypodermic needle comprises a connector for connecting to a hypodermic needle, a sheath (22) which in use surrounds the hypodermic needle and a biasing device (24) between the connector and the sheath. The sheath is moveable between a first position into which it is biased by the biasing device and a second retracted position against the force of the biasing device, so that in use, the tip of the hypodermic needle is covered in the first position but a defined length of the hypodermic needle is exposed in the second position. The device also sets the position of the angle of the hypodermic needle and locks the sheath over the needle after use.