Abstract: A cap assembly mountable to a rigid shield around a needle of a syringe. The cap assembly includes a gripper component and a base cap. The gripper component includes a support frame and a liner that is deformable when sandwiched between the support frame and the rigid shield. When the base cap is installed to the gripper component during manufacture, and with the rigid shield disposed in a bore of the gripper component in any rotational orientation relative thereto, the liner is held by the support frame so as to be deformed against and grip the rigid shield for shield removal purposes so as to allow for removal of the rigid shield from around the needle.

Abstract: A needle assembly can include a needle and a proximal compartment forming a reservoir for collecting blood that flows through an inner lumen of needle. The needle assembly may also include a needle tip shield for capturing a sharpened distal tip of the needle. The needle tip shield can form a fluid pathway through which blood contained within the reservoir is expelled. The volume of the reservoir can be reduced to cause blood to be expelled from the needle tip shield such as by compressing the proximal compartment or a plunger connected to the proximal compartment or by moving a plunger into the reservoir. The fluid pathway of the needle tip shield can either be the same pathway through which the sharpened distal tip is withdrawn into the needle tip shield, or can be a separate pathway.

Abstract: A needle assembly is disclosed. The needle assembly includes a housing having a flash chamber, and having a distal end and a proximal end engageable with a specimen collection container. The assembly includes a cannula having a patient end, a non-patient end, and a sidewall extending therebetween defining a cannula interior. The patient end of the cannula projects at least partially from the distal end of the housing, and the cannula interior is in fluid communication with the flash chamber. The assembly further includes a shield restrainably engaged with a portion of the housing and axially transitionable over the patient cannula from a retracted position in which the patient end is exposed, to an extended position in which the patient end is shielded by at least a portion of the shield, wherein at least a portion of the flash chamber is visible in the retracted position.

Abstract: The present invention relates to a needle assembly having a build-in valve (30). The needle assembly is built up from a hub (20) carrying a needle cannula (10) and a telescopically movable shield (40) which axially covers the distal tip (13) of the needle cannula (10) between injections. The valve (30) is operated by the shield (40) and is arranged such that it is closed when the distal tip (13) of the needle cannula (10) is covered by the shield (40) and is opened when the telescopically movable shield (40) has been retracted a specific distance (X) proximally to the distal tip (13) of the distal cannula part (11).

Abstract: An auto-retracting hypodermic syringe has a housing extending axially to form a collar and housing interacting syringe components, an outer barrel is fixed within or forms part of the housing and an inner barrel is slidably mounted within the outer barrel for rearward movement within the outer barrel, the inner barrel has a mount for mounting a hypodermic needle on it or a needle already within a mount; a plunger has a piston on its distal end for withdrawing liquid dosage into the inner barrel when the plunger is pulled back and for injecting dosage when the plunger is pushed forward; axially-spaced, different-diameter discs on the plunger engage with radially pivoting, hinged latching arms formed on the proximal end of the housing and there are other associated latch members on the inner barrel and the housing which move inwards and outwards in correspondence with forward and rearward movements of the plunger; a coil spring is placed between the housing and inner barrel to exert needle retraction force agai

Abstract: A needle safety device has an outer tube within which a syringe barrel from which a cannula extends is slideably receivable. A collar in the outer tube is moveable relative thereto and rotatably attachable to the distal end of the barrel. A force member biases the outer tube in a distal direction. A cannula shield able to receive the cannula therein is in the outer tube. The cannula shield is fixedly attached to a cap removably attached to the outer tube. A track is formed in the inner surface of the outer tube. A pin extending radially outwardly from the collar slidingly engages the track. In a pre-injection position, the cannula is entirely within the outer tube. In a full-insertion position, the cannula extends beyond the outer tube. In a locked position, the cannula is irreversibly retained entirely within the outer tube.

Abstract: A retractable safety syringe includes a retractable needle hub holding a needle and having a first guiding means; and a hollow barrel having a second guiding means set correspondingly to the first guiding means; and a collapsible plunger comprising of a first plunger element having a protrusion releasably coupled with a second plunger element having a longitudinal slot with a pinched zone to curb the movement of said protrusion; and a spring disposed between the needle hub and hollow barrel and acts between the needle hub and the hollow barrel. The uncoupling of the collapsible plunger triggers the retraction mechanism to enable the needle hub to retract into the barrel by the decompression force of a spring. The reliability of retraction is further improved by a longitudinal slot and a protrusion to facilitate the retreating of the collapsible plunger in an orderly way.

Abstract: A winged injection needle including an injection needle main body, a base that supports the base end of the injection needle main body and wings that protrude from the base toward the left and right sides to function as handles, the wings being constructed with plate members that are freely foldable through hinge sections so that in the folded state, they protrude from the base toward the left and right sides to function as handles, while in the expanded state, they extend from the base along the injection needle main body toward the leading edge of the injection needle to function as a safety cover that covers the injection needle main body.

Abstract: The application relates to needle protection assembly (1)) comprising:—a support (2) of the needle (3),—a needle shield (8) having a longitudinal axis A,—urging means (13) for displacing said needle shield (8) from a “in, use” position to a “after use” position,—a locking element (10) intended to prevent said needle shield (8) from moving back from its “after use” position to its “in use” position, characterized in that said locking element (10) has a longitudinal axis B and is radially movable with respect to said needle shield (8) between a “free” position, in which the longitudinal axis A of the needle shield (8) and the longitudinal axis B of the locking element (10) are merged and in which said needle shield (8) is movable from its “in use” position to its “after use” position, and a “locking position”, in which the longitudinal axis B is radially spaced apart from the longitudinal axis A and in which movement of the needle shield (8) from its “after use” position to its “in use” position is prevented.

Abstract: An injector includes a hollow needle; a main body unit including a needle holding portion that holds the needle; and a protection device configured to cover the needle before and after puncturing a puncture target with the needle. The protection device includes: an inner member attached to the needle holding portion and being freely rotatable around an outer periphery of the needle holding portion; and an outer member configured to (i) cover an outer side of the needle and the inner member before puncturing, (ii) expose the needle by moving toward a proximal end side relative to the main body unit at a time of puncturing, and (iii) cover a distal end of the needle by moving toward a distal end side relative to the main body unit after puncturing.

Abstract: A detent mechanism for controlling translation between two components in a longitudinal direction includes a resilient beam on one of the components and a rhomboid ramp member on the other component. The resilient beam is essentially straight when relaxed and has a first beam head and is arranged to interact in a ramped engagement with respectively one of two ramps. Each ramp is on one longitudinal side of the rhomboid ramp member such that application of a translative force between the components in one longitudinal direction with the first beam head engaged to one of the ramps in a first state deflects the resilient beam in one transversal direction and such that application of a translative force between the components in the other longitudinal direction with the first beam head engaged to the other one of the ramps deflects the resilient beam in the other transversal direction.

Abstract: A safety blood-collection needle, comprising a needle base, a needle hub, a flexible tube, a straight needle, a straight needle shaft, and a needle head; the safety blood-collection needle further comprises a protective cover, a slider, a handle, and a position limiting mechanism; one end of the needle base is fixed and is in communication with the needle head; the slider movably sleeved on the needle base; the position limiting mechanism is arranged on the slider and needle base. The slider is arranged on the needle base and slides in order to cover the needle head, so that safety is greatly increased when handling the needle head following blood collection; the use of a spring-type needle head is avoided, thus reducing the suffering of the patient.

Abstract: A needle safety device (1) has an outer tube (10) within which a syringe barrel (2) is slideably receivable. A collar (14) in the outer tube (10) is moveable relative thereto and rotatably attachable to the distal end of the barrel (2). A force member (16) biases the outer tube (10) in a distal direction. A track (S) is formed in the inner surface of the outer tube (10). A pin (18) extending radially outwardly from the collar (14) slidingly engages the track (S). In a staging position, the barrel is inspectable. In a pre-injection position, the cannula extends a first length beyond the outer tube. In a full-insertion position, the cannula extends a second length greater than the first length beyond the outer tube. In a locked position, the cannula is entirely within the outer tube.

Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.

Abstract: Container holder assembly for use in a medicament delivery device, comprising a tubular body elongated in an axial direction, said tubular body having a proximal end and an opposite distal end, and a retaining member releasably arranged to said tubular body for securing an elongated container placed inside the tubular body, wherein said retaining member comprises a resilient structure capable of exerting an axial force on said container in said tubular body for holding the container in a fixed position inside the tubular body and wherein the retaining member and the tubular body respectively comprises a first and a second locking means capable of achieving a mutual mechanical connection, such that the retaining member is locked to the tubular body.

Abstract: A retractable needle assembly includes a housing having a sidewall defining a hollow bore, and an elongate plunger, the distal end of the plunger forming a reservoir within the hollow bore for containing a fluid therein. The plunger is adapted for slideable movement within the hollow bore. The assembly includes a hub disposed within the hollow bore and at least partially supporting a cannula therewith, and a needle retraction member engaged with the hub for manually selectable advancement with respect to a portion of the housing. The needle retraction member may be advanced from an initial position in which at least a portion of the needle is disposed outside the housing, to a retracted position in which the needle is fully surrounded by the housing. The elongate plunger may be advanced about the hub for extracting the fluid into the reservoir or expelling the fluid from the reservoir.

Abstract: It is an object of the present invention to provide a syringe which is capable of preventing an accident such that a patient inadvertently sticks her/his hand with an injection needle when improperly performing a needle retracting operation. A sleeve (10) is fitted around a syringe barrel (2) so as to be axially movable from an administration position such that the injection needle (5) projects to a distill side to an accommodation position such that the injection needle (5) is accommodated. A coil spring (16) for biasing the sleeve (10) toward the accommodation position is provided between the sleeve (10) and the syringe barrel (2), and is held in a compressed state in a spring holder (17). The spring holder (17) is disposed in association with the syringe barrel (2) so as to release the coil spring by further pushing the syringe barrel (2) to the distal side after completion of the administration of a liquid drug.

Abstract: A medication delivery device included molded cylindrical barrel having visual marks on the surface of the barrel in the axial direction, a plunger seals the distal opening of the cylindrical barrel, a molded needle hub disposed in the proximal opening of the cylindrical barrel for sealing the needle hub to the barrel. A needle is disposed in the needle hub for communicating liquids by operation of the plunger in the axial direction. The circumferential surface on the flange of the needle hub comprises a colored mark that corresponds to a characteristic of the medication delivery device or its contents.

Abstract: Devices and methods are provided for sterile transfer of flowable material between a syringe and one or more flowable material receptacles or between a pair of receptacles. A syringe assembly may include a tip enclosure having a flexible shroud surrounding a syringe tip, with a shroud membrane associated with the distal end of the shroud to enclose the syringe tip. The shroud is deformable to move the tip toward the shroud membrane, which may be traversed by the tip to expose the tip for material transfers. A rigid connector may be positioned at the distal end of the shroud to securely connect the syringe assembly to a receptacle. The plunger and piston of the syringe assembly may include membranes to allow material transfer at the proximal end of the syringe assembly. An adaptor may also be provided for sterilely connecting a receptacle to a syringe or to another receptacle.

Abstract: Described is an autoinjector comprising a case, a chassis slidably arranged in the case, a syringe carrier operably coupled to the chassis, an outer plunger selectively engaged to the chassis, an inner plunger selectively engaged to the outer plunger, and a drive spring applying a biasing force to the outer plunger. The biasing force is applied to the inner plunger when the inner plunger is engaged to the outer plunger. Rotation of the chassis causes the inner plunger to rotate relative to the outer plunger and disengage the outer plunger to remove the biasing force from the drive spring on the inner plunger. When the inner plunger disengages the outer plunger, the biasing force of the drive spring pushes the chassis to retract the syringe carrier relative to the case.

Abstract: An autoinjector includes a rear body assembly (10) connected to a front body assembly, wherein the rear body assembly (10) contains a drive mechanism (60 . . . ) and the front body assembly contains a syringe (13) or cartridge with a needle at its forward end, the front body assembly including a viewing window (22) through which at least part of the contents of the syringe (13) or cartridge are visible, a removable cap (14) fitted to the forward end of the front body assembly the rear body assembly and the removable cap having respective aligned cut-away regions together defining a frame for the viewing window. Also disclosed is a modular scheme which uses a common platform for the provision of a range of autoinjectors of different fill volumes, with only the length of the plunger (60), and the axial extent of the cut out varying between different versions.

Abstract: A cartridge holder for a drug delivery device is presented having snap fastening connection means to fasten the cartridge holder to a housing of the drug delivery device, wherein the fastening connection means are provided with at least on basically rectangular window for receiving a locking element of said housing. The invention is further directed to a pen-type injector equipped with a respective snap fastening connection for the cartridge holder.

Abstract: An autoinjector having a lower body receiving a tank containing fluid product and a piston and a needle. The autoinjector including a central body fastened to the lower body and an actuating sleeve provided with a contact end that contacts the body of the user, the actuating sleeve moveable between a projected position and an actuation position. The actuating sleeve is in a projected position prior to and after actuation of the autoinjector, an injection mechanism is provided to inject the fluid product through the needle when the needle is in an injection position in which it is inserted in the body of the user. The autoinjector includes a tank movement device to move the needle towards the injection position, the tank movement device triggering the injection mechanism only after the needle has reached its injection position.

Abstract: An autoinjector that receives a pre-filled syringe, having a central body and an actuator sleeve provided with one end that comes into contact with the user. The actuator sleeve can be moved between projecting and actuation positions and it is in the projecting position prior to and following the actuation of the autoinjector. An injection mechanism is provided to inject the product when the needle is inserted into the user's body. The autoinjector also includes a barrel movement device to move the needle into the injection position and retract the needle from the body following injection. The movement device includes a control ring rotatably mounted in the central body, the ring having an inclined internal profile that engages with an internal projection of a control sleeve that can move axially in the central body, such that the sleeve moves axially when the ring is rotated.

Abstract: An injection device tip includes a body configured to be removably connected to an injection device and a needle having a portion projecting from a proximal end of the body. The body at least one of has flexible portions which can be deflected inwardly to cause release of an engagement between the body and a proximal end of the injection device, has two oppositely arranged flexible portions arranged outside an imaginary circle defined by an outside surface of two opposite portions arranged between the two oppositely arranged flexible portions, is generally oval in shape, is generally rectangular in shape, is generally square in shape, and is non-circular in shape. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

Abstract: Devices, systems, and methods for performing injections with lowered likelihood of infection include needles and other injection means with protective sleeves or sheaths. The protective sleeve can protect the needle before, during, or before and during an injection. The force needed to administer an injection or penetrate an insertion site using an injection device or system with a protective sleeve can be about the same to up to 50% more than the force needed for a system or device without a protective sleeve. The force needed to collapse the protective sleeve can be less than 100 gram-force. The material, the thickness, or both the material and the thickness of the protective sleeve may differ when comparing the portion of the sleeve near the needle tip and the portion near the base of the needle.

Abstract: A protective device for an injection or infusion needle is provided comprising a needle hub at the proximal end of the needle, on whose shaft a protective member for the needle tip is displaceable, the protective member having an engaging section which engages with the needle shaft to prevent the protective member from being displaced beyond the needle tip, wherein the protective member is surrounded by a tube whose diameter is locally reduced or deformed such that the protective member is confined in the tube.

Abstract: A protective cover for a syringe needle includes a sheath and a needle hub. The sheath preferably includes a cylindrical body terminated with a bullet shaped end. The needle hub includes a needle base and a hypodermic needle retained in the needle base. The need base slides in the cylindrical body. The needle base includes a bullet shape and a locking projection extending from an outer perimeter of the needle base. A lengthwise slot is formed through the cylindrical body. The lengthwise slot is sized to receive a button portion of the locking projection. A retracted locking notch is formed on one end of the extension slot. An extended locking notch is formed on an opposing end of the lengthwise slot. A storage notch is formed adjacent the retracted locking notch. The button portion is retained in the retracted locking notch, the extended locking notch or the storage notch.

Abstract: A filtered needle for use in administering a liquid payload, including a needle and connector portion and a filtering needle cap. The filtering needle cap including a distal open end in fluid communication via an internal channel with a proximal open end of the filtering needle cap. The filtering needle cap proximal end sized to receive the distal end of the hub within the proximal end of the filtering needle cap to reversibly engage the hub when needle distal end is inserted into the internal channel. The filtering needle cap including a filter element and a seal to seal around an outside diameter of the hollow needle so that liquid payload is drawn into the lumen in the hollow needle as liquid payload is filtered and drawn into the fluid fitting. The filtering needle cap is designed to limit a dead volume of liquid payload drawn into the filtering needle cap but not entering into the distal end of the hollow needle.

Abstract: A video stabilization device has an adjustable length shaft with a proximal end, a distal end, and a midsection between the proximal end and the distal end. A video recording device mount adapted to retain a video recording device is associated with the proximal end of the shaft, a counterweight member is associated with the distal end of the shaft, and a 2-axis gimbal is associated with the midsection of the shaft. A user may grasp the 2-axis gimbal and adjust the length of the adjustable length shaft to generally balance a video recording device retained by the video recording device mount and the counterweight member with the shaft in a predominantly vertical orientation thereby stabilizing a video recording produced by the video recording device. The video stabilization device may optionally be balanced in the horizontal orientation as well.

Abstract: Container holder assembly for use in a medicament delivery device, comprising a tubular body elongated in an axial direction, said tubular body having a proximal end and an opposite distal end, and a retaining member releasably arranged to said tubular body for securing an elongated container placed inside the tubular body, wherein said retaining member comprises a resilient structure capable of exerting an axial force on said container in said tubular body for holding the container in a fixed position inside the tubular body and thereby avoiding displacement or breakage of the container and wherein a distal end of said container protrudes from a distal end of said tubular body.

Abstract: The subject invention provides a safety pen needle assembly which includes: a hub; a needle carrier; a needle fixed to the needle carrier; a shield; and, a first engageable locking arrangement for fixing the shield to the needle carrier. Upon a predetermined extent of distal movement of the shield relative to the hub, the first locking arrangement is engaged such that the shield becomes fixed to the needle carrier. Upon further distal movement of the shield relative to the hub beyond the predetermined extent of distal movement, the shield and the needle carrier move in concert together relative to the hub causing a proximal end of the needle to move distally relative to the hub to a retracted state. Advantageously, the subject invention provides a reliable, low-cost safety pen needle assembly which does not require a spring or other biasing element.

Abstract: A safety needle assembly is provided herein which includes a hub; a needle fixed to the hub; a first shield having a tubular body at least partially encircling a portion of the needle, wherein in an initial state, the first shield extends from the hub; a second shield having a tubular body at least partially encircling a portion of the needle; a biasing element disposed to urge the second shield distally towards a distal end of the needle; and, a releasable retaining arrangement for releasably retaining the second shield in a first state. Upon a predetermined extent of proximal movement of the first shield relative to the hub, the second shield is released to a second state in which the distal end of the needle is covered. Advantageously, two shields are provided for at least partially covering a needle with one of the shields acting as a trigger.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having a tubular chassis telescopable in an elongate chassis, a carrier subassembly comprising a tubular carrier slidably arranged partially inside the chassis and inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier.

Abstract: A safety shield for use with a hypodermic syringe device is disclosed. The safety shield is moveable relative to the syringe barrel between retracted position and a needle containing position. In the retracted position, the syringe device may be used to inject the needle into the patient. After the medication has been injected or as the needle is withdrawn from the patient, in its operative mode the shield automatically extends from its retracted position to a needle containing position to shield the point of the needle to prevent accidental sticks and without further input from the operator to render the syringe unusable after a single injection.

Abstract: In a first aspect, a safety pen needle assembly is provided herein which includes a hub and a needle fixed to the hub which extends distally from the hub so as to define an injection length. A first shield is slidable relative to the hub from a first state, in which the shield covers at least a substantial portion of the injection length of the needle, to a second state, in which at least a substantial portion of the injection length of the needle is exposed; and, a second shield is slidable from a first position, in which the shield covers the proximal end of the needle, to a second position, in which the proximal end of the needle is exposed. A biasing element is disposed between the first and second shields configured to simultaneously urge the first shield distally and the second shield proximally.

Abstract: A blood collection assembly includes a housing and a cannula extending distally from the housing including a patient end, and a cannula shield removably engaged with a portion of the housing. The cannula shield is capable of shielding at least the patient end of the cannula, and includes a safety shield engagement. The assembly includes a pivoting safety shield engaged with a portion of the housing, which is transitionable from a retracted position in which the patient end of the cannula is exposed, to an extended position in which the patient end of the cannula is shielded by at least a portion of the safety shield. The safety shield includes at least one locking tab releasably engageable with the safety shield engagement, wherein the locking tab is fixedly engageable with a portion of the housing in the extended position.

Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.

Abstract: The present invention extends to a blood control catheter valve for use in a catheter adapter. The blood control catheter value employs an actuator for bypassing a septum to open the blood control catheter valve. The actuator includes flexible retention arms positioned on one end which retract into the body of the actuator while the end of the actuator passes through the septum, and then expand outwardly to maintain the actuator positioned within the septum. This design facilitates the manufacturing of catheter adapters (as well as blood control catheter valves and other components that attach to the catheter adapter) because the design can reduce the tolerance requirements of such components. Further, the design provides a reliable blood control catheter valve that does not require the catheter adapter to be increased in size to accommodate the valve.

Abstract: A safety device for a pre-filled syringe comprises a hollow support body to retain the pre-filled syringe therein, a hollow needle shield that is slidable relative to the support body and guiding means for guiding the movement of the needle shield relative to the support body. The guiding means comprise a deflectable flexible arm, a guide pin and a guide track. The deflectable flexible arm extends essentially parallel to a central axis of the safety device. The guide pin extends radial from the flexible arm. The guide track guides the guide pin within and along the guide track when the needle shield is slid relative to the support body.

Abstract: A needle shield arrangement for a syringe (10), having a generally cylindrical body with a needle (16) at its forward end, includes a shield portion (20) adapted for shielding the needle (16); a syringe engaging portion (22) for engagement with the syringe body, and a frangible connecting portion (24) connecting the shield portion and the syringe engagement portion.

Abstract: An elastic cap detachably mountable to a barrel tip portion of a barrel so as to seal a tip of a needle hole includes a cylindrical receiving hole configured to receive at least part of a barrel tip portion and a puncture needle of a barrel. The receiving hole includes a first inner diameter portion having a smaller diameter than an outer diameter of the annular head; a stopper portion provided at an end of the first inner diameter portion; and a second inner diameter portion that is formed from the stopper portion to a bottom wall provided at an end of the second inner diameter portion, the second inner diameter portion having a smaller diameter than the first inner diameter portion.

Abstract: The present disclosure describes anti-needle stick safety mechanism that is passively activated during the normal course of giving an injection. In one embodiment, the device includes a spring member coupled at a proximal end to a needle member and at a distal end to a needle cover. The passive activation of the device is triggered when the needle is inserted to a minimum depth into the patient's tissue to unleash the force of a compressed spring to urge a needle cover towards the distal end of the needle. As the needle is withdrawn from the tissue, the needle cover advances to the end of the needle and as it partially clears the end of the needle, it adopts an orientation that prevents the needle tip from re-emerging from the needle cover.

Abstract: A device that is used in conjunction with a needle-based medication injection device (e.g. a prefilled syringe) that prevents needle stick injuries. The used needle is shielded by a needle guard that surrounds and extends beyond the needle tip. In a preferred embodiment, before the needle is inserted into the patient, the needle guard projects forward to substantially hide visibility of the needle for safety and to reduce patient anxiety.

Abstract: A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module is user selectable so that it will deliver a priming dose of a primary medicament or both the primary and secondary medicaments. The module also contains a needle guard that locks after dose delivery. The needle guard prevents accidental needle sticks before and after an injection. A locking collar rotates during use as an inner protrusion follows three paths of a track located on the outer surface of a body housing. When the inner facing protrusion is in the third path, it encounters a hard stop and a rotational bias that locks the guard from further refraction and thus covers the sharp distal end of the needle.

Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.

Abstract: A safety device for shielding the sharp tip of a medical needle has a needle mount which either directly supports a medical needle, or indirectly supports the needle for instance where the needle is provided as a part of a syringe. A sleeve is carried directly or indirectly on the needle mount and is slidably movable to a needle shielding position where the sleeve surrounds the needle sharp tip. A spring including forwardly projecting spring blades when sufficiently loaded acts on an internal conical surface of the sleeve to drive the sleeve to its shielding position and a locking mechanism then locks the sleeve in that position. A camming mechanism serves to load the spring blades in the course of the use of the safety device such that thereafter the interaction of the blades with the conical surface urges the sleeve to its shielding position, the camming mechanism being activated by movement of the sleeve to expose the needle for use.

Abstract: A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, a plunger assembly slidably received within the tubular body at the proximal end thereof, and a hollow needle secured within the tubular body at the distal end thereof. The tubular body includes a longitudinal opening located between the proximal and distal ends that is adapted to allow a substance cartridge to be inserted within the tubular body. The plunger assembly includes a plunger that is in slideable sealing engagement with an inside wall of the tubular body, an engagement head positioned proximate an opposite end of the longitudinal opening, and a rod extending between and connecting the plunger and engagement head.

Abstract: A liquid administration device includes: a cylindrical body filled with liquid; a needle tube configured to communicate or be communicable with the cylindrical body at its tip side, and to have a sharp needle tip; a gasket configured to slide within the cylindrical body; an operation member configured to to discharge the liquid by pressing the gasket toward the tip direction; a cover member configured to be capable of moving to a first position, in which at least the needle tip is covered, to a second position, in which the needle tip is exposed, and to a third position, in which at least the needle tip is re-covered; and a cover member that can move from the first position to the second position to a third position to re-cover the needle tip.

Abstract: Described is a needle safety device comprising a needle hub including an axial stem having one or more grooves, a needle having a distal tip, a needle shield telescopically coupled to the needle hub and including a first aperture for allowing the needle to pass through, and an inner sleeve rotatably coupled to the needle shield and including a second aperture for allowing the needle to pass through. The inner sleeve includes one or more resilient arms adapted to engage the groove. In a first axial position and a first angular position, the needle shield covers the distal tip of the needle and the first aperture is aligned with the second aperture. In a second axial position, the distal tip of the needle is through the first aperture and the second aperture and extends distally beyond the needle shield. In a third axial position and a second angular position, the needle shield covers the distal tip of the needle and the first aperture is not aligned with the second aperture.