Abstract: The present disclosure describes an extended finger flange that facilitate use of syringe systems. The extended finger flange increases the surface area available for an end user's fingers thereby allowing a more secure grip on the device and providing greater control during administrations of the medication.

Abstract: Described is a medicament cartridge comprising a housing having open proximal and distal ends, a first coupling mechanism, and a syringe slidably disposed in the housing. The syringe includes a needle and has a retracted position in which the needle is covered by the housing and an extended position in which the needle is exposed. A delivery device comprises the medicament cartridge, an actuator comprising a plunger, a motor adapted to translate the plunger, a second coupling mechanism adapted to detachably engage the first coupling mechanism, and a control button adapted to actuate the motor. A carrier comprises a first slot for at least partially containing the actuator, a second slot for at least partially containing the medicament cartridge, a user interface adapted to provide at least one a visual signal and an audible signal.

Abstract: A medicament delivery device has a housing and a sleeve; a shield within and protruding from the housing; a container having a delivery member, a chamber containing a medicament, and a piston; a drive mechanism having a spring and a plunger rod in contact with the piston; and a container holder having a first locking device releasably connected to a corresponding locking device on the sleeve for holding the holder in an initial state against the drive mechanism and a second locking device surrounded by the sleeve and releasably connected to a corresponding locking device on the plunger rod for protecting the piston from force from the drive mechanism until the holder has moved a certain predetermined distance. The shield releases the first locking device when the shield is pressed against a medicament delivery site, whereby the drive mechanism forces the holder the certain predetermined distance.

Abstract: A safety needle pack has a safe needle device contained within a housing 10, for use with a syringe 20. The device has a needle hub 16 supporting a needle 17 and a sleeve 22 is slidably mounted on the hub for movement between an initial position to an intermediate position where the tip region 31 of the needle 17 projects from the sleeve 22 and a protecting position. Following use of the safe needle device, the sleeve 22 is moved under the action of a spring 24,29,30 to the protecting position, a locking mechanism 29,40 then restraining the sleeve in that position. The rotational connection of a syringe 20 to the needle hub 16 turns the safe needle device within its housing 10, this causing the sleeve 22 to move rearwardly with respect to the housing from its initial position to its intermediate position so as to be ready for performing a medical procedure.

Abstract: An injection device comprises a first sub-assembly. The first sub-assembly comprises a chamber for holding a fluid. The chamber comprises an inner surface and an exit aperture. The first sub-assembly comprises a stopper movably disposed within the chamber and having an outer surface substantially in contact with the inner surface about its perimeter. The first sub-assembly comprises an adapter adapted to transfer fluid into the chamber.

Abstract: A safety shield adapted for use with a syringe having a syringe barrel for protecting a needle after use in a medical procedure is disclosed. The safety shield includes a first portion disposed at least partially about the barrel and axially movable from a retracted position surrounding at least a portion of the syringe barrel to an extended position wherein at least the distal end of the first portion extends beyond the distal end of the syringe barrel. The shield further includes a second portion associated with the first portion and axially movable with respect to the first portion from a retracted position to an extended position extending beyond the distal end of the first portion. First and second locking members are provided for locking the first and second portions in an extended position upon axial movement thereof.

Abstract: A needle safety shield 10 for use with a syringe 10 having a barrel 14, a needle and a plunger rod 16. The safety shield 10 has a first tube 22. A second tube 26 is arranged for sliding movement within the first tube 22. A pin 46 is connected to one of the first and second tubes 22, 26. An activation ring 32 has a stop 72. A drive spring 34 biases the activation ring 32 in a proximal direction to place the stop 72 in engagement with the pin 46 to retain the first and second tubes 22, 26 in a retracted configuration. The movement of the plunger rod 16 to engage the activation ring 32 compresses the drive spring 34, moving the activation ring 32 distally, and moving the stop 72 out of engagement with the pin 46, allowing the drive spring 34 to move the first and second tubes 22, 26 into an extended configuration.

Abstract: Provided is a microneedle unit comprising a case having a space accommodating a fluid and a fluid channel through which the fluid is discharged, a microneedle coupled to a lower portion of the case, a base cover disposed at the lower portion of the case, having a hole through which the microneedle passes, and being vertically movable, a guide pin coupled to the base cover and configured to open and close the fluid channel, and an elastic member configured to impart a restoring force such that the base cover is moved upward by an external pressure and then returns downward again. Therefore, the microneedle unit, which is provided to deliver a fluid into the skin with no pain and no scar, can control injection of the fluid using the guide pin, and repeatedly and conveniently control injection of the fluid using the elastic member.

Abstract: An injection device has a main drive module which can be screwed into the back of a syringe housing to prepare the injector ready for use. The drive module has a firing button and a drive plunger released for forward movement by pressing the firing button. The syringe housing slideably receives a syringe holder whose forward movement is initially prevented by internally directed barbs on a cylindrical latching sleeve. The latching sleeve is acted upon by a release ring on the drive module such that as the drive module is screwed onto the syringe housing, the release ring splays the cylindrical shell to release the syringe carrier for forward movement. The barbs also act as a latch to capture the syringe carrier in its rearward position when the drive module is unscrewed from the syringe housing, which returns the barbs to their initial position before the syringe holder returns to its initial position.

Abstract: A liquid administration device includes a cylindrical body; a needle tube configured to communicate or to be communicable with the cylindrical body at a tip side of the cylindrical body; a gasket that is slidable within the cylindrical body; an operation member configured to perform pressing operation to discharge the liquid from the needle tube by pressing the gasket toward the tip direction; a restricting member arranged at an outer peripheral side of the cylindrical body, and configured to be positioned to restrict the pressing operation; and a cover member that is movable to a first position, in which at least the needle tip of the needle tube is covered, and to a second position, retreated in a base end direction from the first position, in which the needle tip is exposed.

Abstract: A protective sheath (100) for a cannula (210) arranged on a hub (200) which can be fitted onto a syringe (300), the sheath including female elements intended to cooperate with male elements (201) of the hub (200) for guiding thereof, and characterized in that the female elements include a retracted position before use RBU, a retracted position during use RU, and a retracted position after use RAU, wherein the whole length of the cannula (210) is inside the sheath (100), the female elements further include an ejection position E, wherein whole or part of the cannula (210) protrudes out of the sheath (100), and further characterized in that at least two of the RBU, RU, and RAU positions are substantially transversally aligned.

Abstract: An autoinjector comprising a lower body (10) receiving a tank, said tank containing fluid product and comprising a piston and a needle, such as a pre-primed syringe (A), said autoinjector comprising: injection means (5, 8) to inject said fluid product through said needle when said needle is in an injection position; and a tank movement device (2, 4, 9) for retracting said needle out of the body of the user after injection of the fluid product, a trigger (19), actuated by said injection means, actuating said tank movement device (2, 4, 9) after injection of the fluid product so as to retract said needle; said autoinjector comprising a retarding device (15, 16, 17) adapted to delay during a predetermined time the actuation of said tank movement device (2, 4, 9) by said trigger (19) after injection of the fluid product, to delay retraction of said needle by said predetermined time after the end of injection.

Abstract: The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152, 153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201, 202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201, 202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

Abstract: A device for the automatic injection of doses of a drug compound is described. The device has a sliding sheath which, when depressed with its front end against the injection site, interacts with cam means to activate triggering of a plunger, thus controlling delivery of a drug dose. Plunger guide means are provided for controlling the triggering sequence and means for arming the device in the dose delivery condition. Automatic needle re-sheathing and resetting of a lock-out condition after each dose is delivered are also provided.

Abstract: In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors which are sold or distributed filled and with the springs tensed have to be provided with a needle protecting cap to ensure the sterility of the injection needle. When such a needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container comprising the injection needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve which accommodates the active agent container. When the auto-injector is placed onto a person's skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange and, thus, freeing the travel path for needle movement.

Abstract: The invention relates to a sleeve for an injection device comprising a container having an outer flange, said sleeve being provided with one inner radial projection intended to prevent the proximal movement of said outer flange with respect to said sleeve once said container is received within said sleeve, said sleeve being further provided with one inner longitudinal projection extending distally from said inner radial projection and intended to limit the radial movement of said outer flange, said inner radial projection and inner longitudinal projection being provided on a longitudinal leg connected to said sleeve by a deformable bridge allowing radial deflection of said longitudinal leg outwardly when a distal pressure is exerted on said inner radial projection, and inwardly when a proximal pressure is exerted on said inner radial projection. The invention also pertains to an injection device comprising such a sleeve.

Abstract: A portal access assembly includes an inserter that has a needle, a cap moveable along the length of the needle and an infuser having a cannula through which the needle extends. A safety mechanism inside the cap allows the needle to be moved relative to the cap so long as the shaft of the needle biases against an edge of one of the legs of the mechanism. After the cannula is properly positioned in the implanted port to establish a fluid path between the port and the infuser, the needle is removed by being pulled upwards until it no longer biases the one leg of the mechanism. At which time the safety mechanism fixedly captures the needle inside the cap to prevent the contaminated tip of the needle from being exposed to the environment. At the same time, the cap is detached from the infuser.

Abstract: A cannula insertion device includes a housing defining an opening for receiving therethrough a cannula and further defining a channel, and a cannula forming a lumen, the cannula adapted for sliding movement within the housing from a retracted position to an extended position. When the cannula is in the retracted position, the lumen is located remotely from the channel and the channel is in fluidic communication with the opening. When the cannula is in the extended position, the lumen is in fluidic communication with the channel.

Abstract: The present invention relates to an injection device (1) comprising:—a body (3) designed to receive a product to be injected, furnished at its distal end with an injection needle (7) and receiving a piston (5) capable of being moved between a storage position and an end-of-injection position under the effect of a distal pressure exerted on a piston rod (8) to the distal end of which it is attached,—means of protecting the injection needle (7) capable of adopting an initial position, during which the injection needle (7) is uncovered, and a final position, in which the said injection needle (7) is covered, —biasing means (26) aiming at moving the said covering element (6) from its initial position to its final position,—immobilization means (16, 31) aiming at keeping the said covering element (6) in its initial position, the said injection device (1) being characterized in that:—the said piston rod (8) comprises at least a first portion (9) and at least one second portion (10) coupled to the said piston (8), t

Abstract: The present disclosure describes anti-needle stick safety mechanism that is passively activated during the normal course of giving an injection. In one embodiment, the device includes a spring member coupled at a proximal end to a needle member and at a distal end to a needle cover. The passive activation of the device is triggered when the needle is inserted to a minimum depth into the patient's tissue to unleash the force of a compressed spring to urge a needle cover towards the distal end of the needle. As the needle is withdrawn from the tissue, the needle cover advances to the end of the needle and as it partially clears the end of the needle, it adopts an orientation that prevents the needle tip from re-emerging from the needle cover.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: An indwelling needle assembly and protector. The indwelling needle assembly has an inner needle, an inner needle hub, an outer needle, an outer needle hub, and a protector for protecting the needle point of the inner needle arranged on the outer periphery of the inner needle so as to be slidable in the axial direction. The protector includes a protecting member in which the needle point of the inner needle is stored and a closing member arranged on the outer periphery of the protecting member so as to be capable of sliding, a displaceable side wall which is capable of being displaced inward so as to close a distal opening of the protecting member, the displaceable side wall being displaced inwardly by the closing member arranged on the outer periphery of the distal end portion of the protecting member.

Abstract: A device for receiving a hypodermic syringe comprises an outer housing which has at one end a supporting element with an opening for an injection cannula and which has on its inner surface fixing means for engaging in counter-fixing means which are arranged on the outer surface of an injection container, and a displacement element which has at its end opposite the supporting element an actuating element on which at least one means is arranged which, during displacement, tensions a spring element with the build-up of a restoring force and, if a hypodermic syringe is received in the device, disengages the fixing means from the counter-fixing means. The spring element is disposed such that the outer housing and the injection container are moved relative to one another by the restoring force to such an extent until the injection cannula is fully received in the outer housing.

Abstract: A hypodermic injection device configured to be attached to a portable electronic device is disclosed herein. The hypodermic injection device can be an auto-injector for delivering a dose of an injectable medicament. The injection device can include a durable barrier providing a sheath over an injectable cannula to maintain sterility of an injectable cannula that delivers the medicament. The injection device can also include tamper proof features such as by requiring that deployment of the device only be possible after completing two mechanical manipulations so as to prevent accidental discharge of the injection device. By incorporating the injection device within a case for a portable electronic device, the injection device is readily available to those that rely on auto-injectors to provide emergency therapeutic treatment, and is much less likely to be forgotten or left behind by a user than a typical auto-injector.

Abstract: Described is a medicament cartridge comprising a housing adapted to contain a syringe containing a medicament, a shield telescopically coupled to the housing and translatable relative to the housing between a retracted position and an extended position, and a data storage device including medicament data.

Abstract: A medicament delivery device is presented having a housing, a safety sleeve movable between an extended position and a retracted position relative to the housing, a guide sleeve rotatably disposed in the housing, a plunger slidably disposed in the safety sleeve, and a button coupled to the housing. When the safety sleeve is in the retracted position, translation of the button relative to the housing causes the guide sleeve to rotate relative to the safety sleeve. Rotation of the guide sleeve relative to the safety sleeve allows the plunger to translate a predetermined axial distance relative to the safety sleeve.

Abstract: A safety support device for a syringe comprises a support sheath for the body of the syringe and an inner sheath suitable for sliding relative to the support sheath between a waiting, retracted position and the extended position for protecting the needle of the syringe. The device has means for holding the syringe body relative to the support sheath and retaining means suitable for being activated to retain g the inner sheath in the waiting, retracted position inside the support sheath and for being deactivated by the piston of the syringe to allow the inner sheath to extend into its protective, extended position.

Abstract: Catheter assemblies are described having a catheter hub with a catheter tube and a needle hub with a needle projecting through the catheter tube. The catheter hub has at least two seals with at least one being a temporary seal that ends or terminates upon movement of a needle and/or a guard. Different needle guards are provided that can be seated differently within the catheter hub to seal against the elastic seal.

Abstract: A syringe for injecting medicament having automatic needle extension and retraction the syringe includes a first body with a cylindrical cross-section, which includes a front end and a rear end. The front end is provided with a means of transport smaller in diameter than the first body, which is fastened to same with a first fastening protrusion. The means of transport include a male frustoconical element which in turn includes conduits to transport said medicament, the front end further including a sealing protrusion and, located above said first fastening protrusion and said first sealing protrusion, a first alignment protrusion, inside said first body there is also a first elastic element which is fastened to said rear end of said first body with a posterior spring clip, and to said means of transport with an anterior spring clip, the rear end of said first body includes a handle.

Abstract: According to the invention, an injection device (D) comprises a pre-filled syringe and a safety device. The pre-filled syringe comprises a barrel with an inner cavity in fluid communication with a hypodermic needle attached to a distal end of the pre-filled syringe and a piston fluid-tightly sealing a proximal end of the inner cavity. The safety device comprises a support body for retaining the pre-filled syringe therein, an outer body operably connected to the piston, a needle shield and a releasable retaining means (R). The retaining means comprises a radial projection and a longitudinal recess adapted to receive the radial projection. The radial projection is connected to or integral part of one of the support body or the outer body and a longitudinal recess formed into the other of the support body or the outer body. The needle shield, the support body and the outer body are telescopable relative to each other.

Abstract: The present invention relates to a cap assembly 10 configured to be connectable to a suitable medicament delivery device having a distal and a proximal end. The cap assembly 10 according to the present invention comprises a removable outer 12 cap and a removable inner 16 cap movably connected in relation to each other. Further, said cap assembly is configured to allow said removable outer cap and said removable inner cap to be fixedly connectable to each other such that the removable outer cap is prevented of being movable with respect to the removable inner cap only when the medicament delivery device is held in a substantially vertical position such that both said removable outer cap and said removable inner cap can be removed from the cap assembly.

Abstract: A passive safety device for a medical needle has a mount for supporting the needle and a needle shielding sleeve co-axial with and arranged for sliding movement relative to the mount, from a shielding position to a non-shielding position. An abutment surface is provided on one of the sleeve and mount and is engageable by a radially deformable finger, when undeformed. A control member is also slidably arranged with respect to the mount and sleeve and has an initial set position. The control member co operates with the finger so that on sliding movement of the sleeve from its initial shielding position, the finger is moved radially outwardly, clear of the abutment surface and on to a sliding surface.

Abstract: A shielded pen needle assembly is provided in which the hub extends distally beyond an outer sleeve of the assembly.

Abstract: A needle tip for an injection device includes a body having a front portion, a back portion configured to be removably connected to the pre-loaded injection device, and a wall separating the front and back portions. A hollow needle has a first piercing portion projecting back from the separating wall and a second piercing portion projecting forward from the separating wall. A safety shield that is axially movable relative to the body at least between an initial position, a retracted position, and a post use locking position. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

Abstract: A medicament delivery device is presented having a housing configured to receive a medicament container having a delivery member and a shield, a protective cap, and wherein the protective cap comprises connecting means for connecting to the shield of the medicament container such that removal of the protective cap from the housing causes removal of the shield from the medicament container. The delivery device is characterised in that a protective cap assembly has a first disconnecting means configured to interact with corresponding second disconnecting means of the housing and of the protective cap such that activation of the first disconnecting means of the protective cap assembly causes the displacement of the protective cap relative to the housing.

Abstract: A pre-filled, single-use injection device includes a passive dual shield on the patient end of the needle. The device is self-contained so that the entire needle is shielded after use without a separate passive shield system for the non-patient end.

Abstract: A disposable auto injector (10) having a housing for accommodation of a syringe (18) with a needle movably positioned in the housing between a first position in which the needle is inside the housing and a second position in which the needle protrudes outside the housing, a driver (22) positioned laterally in relation to the syringe and configured for applying a force to the syringe thereby moving the syringe from the first position to the second position, a first injection lock configured in a locked state for preventing syringe movement from the first position to the second position and an injection trigger member (16) configured for releasing the first injection lock to an unlocked state wherein the first injection lock comprises a rotatable release shaft (34) configured for rotation between a first angular position in which it prevents movement of the syringe from the first position to the second position and a second angular position in which position does not prevent movement of the syringe from the fir

Abstract: An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the sleeve and contacts the distal end of the syringe. A shield remover extends through an opening in a proximal end of the housing for removing a needle shield which covers a needle of the syringe. A cassette identification arrangement is provided on a surface of the housing to enable the autoinjector to identify the cassette. The autoinjector is provided with a detector for reading the cassette identification arrangement.

Abstract: A connector mountable to a syringe barrel has a proximal barrel-engaging portion, a distal luer fitment portion, and a fluid aperture therethrough. The barrel-engaging portion of the connector includes an axial ledge configured to abut the axial distal edge of a glass syringe barrel. The connector facilitates mounting a luer assembly to the barrel. The luer assembly may be a tip cap having a complementary luer fitment for connection to the luer fitment portion of the connector. The luer assembly may be a luer needle assembly having a complementary luer fitment for connection to the luer fitment portion of the connector. The connector and syringe may further include an immobile, compressible needle seal. The needle seal is adjacent to or engageable with the barrel-engaging portion of the connector. The syringe may be configured with a plunger capable of engaging a retractable needle.

Abstract: The present invention provides various systems, a kit, and a method for accessing, sampling within, and visualization of areas within the mediastinal cavity for assisting a surgeon in performing a mediastinoscopy procedure. The access system includes one or more preferably toroidal balloons that can be expanded to dilate and protect the inner walls of a bodily conduit. Instruments pass through hollow spaces within the expanded toroidal balloons. The proximally positioned balloons are expanded first and the unexpanded balloons to be positioned distally are passed through them and subsequently expanded. The sampling system includes an instrument with a rounded head having two or more jaws and a slit therein at the distal end of an elongated tubular body. The visualization system includes a 360° camera that can be positioned from proximal to distal a target site and can also do a U-turn about its axis of extension.

Abstract: 1. A safety hypodermic syringe (1) comprises a barrel (3) having a plunger operated piston therein and a hollow spigot (11) extending from one end (7) of the barrel (3) and connected to the interior of the barrel (3) An hollow needle (13) is detachably attached to the spigot (11) by means of a cup portion (15) at the end of the needle (13) away from the point (18), the spigot (11) having a reduced diameter portion at its distal end for receipt of the needle cup portion (15) so that the cup portion (15) lies substantially flush with the remainder of the spigot (11). A cap (31) is detachably fitted to the said one end (7) of the barrel (3) so as to cover the needle (13).

Abstract: In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors which are sold or distributed filled and with the springs tensed have to be provided with a needle protecting cap to ensure the sterility of the injection needle. When such a needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container comprising the injection needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve which accommodates the active agent container. When the auto-injector is placed onto a person's skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange and, thus, freeing the travel path for needle movement.

Abstract: The autoinjector systems disclosed herein provide in part devices for allowing patients with reduced joint strength to more easily administer medicine. Certain exemplary syringe embodiments include a housing, a syringe assembly slidably mounted on the housing, and a needle cap releasably engaged to the housing, where the cap includes a protruding pocket for receiving a needle cap remover.

Abstract: A medical injection device has a syringe. The syringe has a container for the medium to be injected and an injection cannula, which communicates with the container. A needle guard of the injection device can be moved between an injection position and a safe position. In the injection position, the injection cannula can be uncovered in order to inject the medium. In the safe position, a cannula tip of the injection cannula is recessed in a protective component of the needle guard. A securing device securely fixes the protective component in the safe position. The result is an injection device having a needle guard that can be manipulated intuitively and operated safely.

Abstract: A medical injection device has an injection unit and an anti-rotation device. Said anti-rotation device is non-rotationally connected to a port and connection portion of the injection device so as to surround the outside thereof in the manner of a sleeve. As a result, an intuitively usable and operationally safe injection device is obtained. When a protective cap for an injection cannula of the injection unit is being removed from the port and connection portion, an unwanted rotation of the port and connection portion relative to the container about components of a plug-in connection arranged therebetween is safely prevented.

Abstract: The present invention relates to a safety pen needle device comprising a generally tubular hub having a proximal and a distal end, said hub comprising attachment means arranged at its distal end for attaching the safety pen needle device to a medicament container assembly, and a coaxially arranged needle attachment member; an injection needle having an injection end and a non injection end, said injection needle being attached inside said hub and extending through the needle attachment member; wherein said device further comprises a generally tubular rotatable sleeve rotatable arranged on said hub, said rotatable sleeve comprising on its outer circumferential surface at least one guide track comprising flexible means; a generally tubular needle shield slidably arranged on said rotatable sleeve, said needle shield comprising at least one guide protrusion on its inner circumferential surface, wherein said at least one protrusion is arranged to interact with said at least one guide track and with said flexible m

Abstract: An auto-injector comprising a housing arranged to contain a slidably arranged syringe. The housing having a distal end and a proximal end with an orifice. Spring means is capable of, upon activation: pushing the needle into an advanced position and into an injection site, operating the syringe to inject a dose of medicament, and retracting the syringe. Activating means locks the spring means in a pressurized state prior to manual operation and capable of releasing the spring means for injection. The spring means is a compression spring grounded distally in the housing and proximally bearing against a thrust tube arranged to transmit load from the spring means via a plunger to the syringe and/or the stopper. A tubular syringe carrier is arranged for holding the syringe and supporting it at a proximal end, the syringe and the syringe carrier arranged for joint axial translation.

Abstract: Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH-adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.

Abstract: The application relates to a needle protection assembly (1) comprising:—a supporting element (18) and a needle shield (8),—one locking element (20) located within said needle protection assembly (1) and not accessible to the user,—urging means (24) for displacing said needle shield (8),—a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and—said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.

Abstract: A needle safety device (1) has an outer tube (10) within which a syringe barrel (2) is slideably receivable. A collar (14) in the outer tube (10) is moveable relative thereto and rotatably attachable to the distal end of the barrel (2). A force member (16) biases the outer tube (10) in a distal direction. A track (S) is formed in the inner surface of the outer tube (10). A pin (18) extending radially outwardly from the collar (14) slidingly engages the track (S). In a staging position, the barrel is inspectable. In a pre-injection position, the cannula extends a first length beyond the outer tube. In a full-insertion position, the cannula extends a second length greater than the first length beyond the outer tube. In a locked position, the cannula is entirely within the outer tube.