Abstract: A substance delivery device including a casing formed by a first casing portion for a substance reservoir including a piston, a piston rod movable in an advancing direction to move the piston toward an outlet of the reservoir to deliver the substance, a dosing element which performs a dosing movement relative to the casing and, together with the piston rod, performs a delivery movement in the advancing direction, a dosing member connected to the dosing element wherein the dosing member is movable generally transversely to the piston rod to enable the piston rod to be moved counter to the advancing direction, a resetting element movably connected to the first casing portion to perform dosing member and piston rod disengaging and engaging movements, and a cam gear coupling the resetting element to the dosing member, wherein the cam gear forms a guiding rail on which the dosing member is guided.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the drive sleeve is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.

Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.

Abstract: An injection device for use with tissue of a mammalian body comprising a first tubular member and a second tubular member slidably disposed in the first tubular member. The first and second tubular members have respective proximal and distal extremities. The distal extremity of the second tubular member is provided with a needle that is extendable from the distal extremity of the first tubular member. The proximal extremity of the second tubular member is lockable relative to the proximal extremity of the first tubular member. The second tubular member has a column strength when locked within the first tubular member for limiting retraction of the second tubular member relative to the first tubular member during puncture of the tissue by the needle.

Abstract: A device for the dosed administration of an injectable product, including a housing with a receptacle for the product and a drive mechanism movable via a dosing element supported displaceably in the housing, wherein the drive mechanism includes engagement elements situated together in groups, the distance between the groups corresponding to a dosing amount of the injectable product and the distance between the engagement elements corresponding to a priming amount of the injectable product, and wherein the dosing element is coupled to the drive mechanism so that the dosing element at one time interacts with a group of engagement elements to administer the dosing amount and at another time interacts with an engagement element to release the priming amount.

Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen.

Abstract: A medication dispensing apparatus having a manually operable plunger axially shiftable relative to the apparatus housing. The plunger is pullable relative to the housing in a proximal direction to cock the apparatus, and when the plunger is then manually pushed back toward the housing, a piston within a medicine container of the apparatus is shifted to force medication from a needle assembly at the distal end of the apparatus. The medication dispensing apparatus also includes a priming mechanism which is operated by rotating an externally accessible driver portion to prime the apparatus for use, which priming can be performed whether or not the apparatus is in a cocked state.

Abstract: Automatic liquid drug preparation apparatus for preparing a liquid drug assemblage with a predetermined dosage of liquid drug. The liquid drug assemblage is prepared from a preparatory assemblage including a fluid control device having a body member with a syringe port, a vial adapter, and an administration port, a vial pre-filled with powder or liquid medicament, and a syringe pre-filled with diluent for mixing with the medicament. The automatic liquid drug preparation apparatus includes a housing, a cradle for receiving the preparatory assemblage, and a controller for controlling a motorized syringe drive unit for selectively transferring liquid contents between the syringe and the vial, a motorized cradle drive unit for selectively rotating the cradle relative to the housing, and a motorized vial adapter release unit for selectively detaching the vial adapter with its attached spent vial from the body member to form the liquid drug assemblage.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: The invention relates to applicators (1) for implantation of an implant, having a cylinder (2) and a plunger (3) displaceably mounted therein, which plunger (3) has a pusher plunger (31) for pushing the implant out of a cannula, the cannula being mounted on a cylinder part, the cylinder part (4) being movably guided in the cylinder (2), there being provided a gear mechanism (5) which couples the plunger (3) to the cylinder part (4), a movement of the plunger (3) relative to the cylinder (2) being converted into an opposite movement of the cylinder part (4).

Abstract: A flexible piston rod includes a piston and a row of elements, the top surface of one element being connected to the bottom surface of an adjacent element by a hinge that allows the two adjacent elements to pivot from a first position, where a portion of the top surface of one element abuts a corresponding portion of the bottom surface of the adjacent element and corresponding to a rectilinear, relatively stiff configuration of the piston rod, to a second position wherein the top surface of one element is spaced from the bottom surface of the adjacent element and corresponding to a curved configuration of the piston rod. Each element has cylindrical surface portions incorporating a thread for meshing with a corresponding thread of an actuator for displacing the piston rod longitudinally.

Abstract: A pressure applicator for applying pressure to a flowable implant material, e.g., PMMA. A pressure applicator or driver includes a pair of columns which are engageable with one another, preferably by threads to generate a driving pressure. A handle is provided for the operator to grasp and steady the device as he turns the handle to apply pressure to the implantable material within the applicator. A luer-lock or other connecting device is provided for attaching the applicator to a cannula (or a connecting conduit that in turns connects with a cannula) that will deliver the implant material to the desired site. Pressures of about 1000-3000 psi may be generated by this device.

Abstract: A force amplifier has a guide track, a non-locking screw threadedly engaging the track to spirally move in response to an axial input force applied to the proximal end of the non-locking screw. The force amplifier includes a compliant component coupled to the non-locking screw by one end and to a self-locking screw by the other end. The compliant component is configured to transmit a torque generated by the non-locking screw to the self-locking screw, which is actuated to move spirally along the track while generating an axial output force greater than the input force.

Abstract: A cannula for dispensing fluid products for vaginal and anal applications comprising an inner tubular body for containing a fluid product, which is provided, at a first end, with an outlet for dispensing the product and, at a second end that lies opposite the first end, with a grip, at least one rectilinear longitudinal slot that is formed on the lateral surface of the inner tubular body, an outer tubular body, which is open at its two opposite ends and is fitted substantially coaxially over the inner tubular body and is associated therewith a rotary coupling, a helical guide formed on the inner lateral surface of the outer tubular body, a plunger, which is accommodated in the inner tubular body, with which it is associated so that it can slide axially, and is provided with at least one pin, which is inserted so that it can slide within the rectilinear longitudinal slot and is provided with an end that extends beyond the rectilinear longitudinal slot and couples to the helical guide, and removable elements fo

Abstract: An administering apparatus for administering an injectable substance in doses is provided. The apparatus includes a casing with a reservoir for the substance, a conveying mechanism which acts to deliver a selected dose of the substance from the reservoir, a dosing and activating mechanism which performs a dosing movement and a delivery movement, and which is coupled to the conveying mechanism such that the delivery movement causes the selected dose to be delivered, a dosage indicator sleeve coupled to the dosing and activating mechanism, and a blocking member in a blocking engagement with the dosing and activating mechanism.

Abstract: A delivery device includes first and second housing portions that selectively engage and disengage. A reservoir on one housing portion operatively engages a drive device and/or a needle inserting device on the other housing portion. Upon proper engagement of the housing portions, the reservoir operatively couples to the drive device and/or the needle inserting device. A first magnet on the first housing portion and a second magnet (or a magnetically-attractive material) on the second housing portion are positioned to magnetically interact with each other, upon operative engagement of the housing portions. A third magnet on the second housing portion may be opposed to the first magnet to help align the housing portions for connection. A magnet-responsive device may be on one or both housing portions to detect alignment and/or connection of the housing portions.

Abstract: An administering apparatus including a casing, a reservoir, a piston accommodated in the reservoir such that it can be shifted in an advancing direction, a piston rod which acts on the piston in the advancing direction and forms a first locking mechanism, a second locking mechanism which cannot be moved counter to the advancing direction, a lock element row formed by successively arranged first locking elements, extending in the advancing direction, and formed by one of the locking mechanisms, and a second lock element formed by the other locking mechanism and engaged with the lock element row, wherein it engages with a lock element gap of the lock element row, wherein the second lock element is moved out of engagement by a movement, against an elasticity force, of the piston rod in the advancing direction, but, when engaged, counteracts a movement of the piston rod counter to the advancing direction with a resistance force greater than the elasticity force to prevent the piston rod from moving counter to the

Abstract: A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The member receives a force from a user and drives the piston in the distal direction to expel medication. A intermediate system is disposed between the member and the piston including a gear set that has a pinion in meshed engagement with a rack. The system allows the member to move a greater distance than the piston moves thereby increasing the force on the piston.

Abstract: A substance delivery device including a casing formed by a first casing portion for a substance reservoir including a piston, a piston rod movable in an advancing direction to move the piston toward an outlet of the reservoir to deliver the substance, a dosing element which performs a dosing movement relative to the casing and, together with the piston rod, performs a delivery movement in the advancing direction, a dosing member connected to the dosing element wherein the dosing member is movable generally transversely to the piston rod to enable the piston rod to be moved counter to the advancing direction, a resetting element movably connected to the first casing portion to perform dosing member and piston rod disengaging and engaging movements, and a cam gear coupling the resetting element to the dosing member, wherein the cam gear forms a guiding rail on which the dosing member is guided.

Abstract: An injection device for injection of set dose of liquid medicine from a cartridge has a piston rod (4, 104)/nut (3, 113) assembly where a nut is screwed up along a threaded piston rod during a dose setting operation. During administration of the set dose the nut is also screwed along the piston rod, thus making the piston rod/nut assembly either longer or shorter. During dose setting the nut is screwed along the piston rod by rotating a dose setting drum (17). An injection button is coupled to the piston rod with a gear wheel transmission (9, 109). Movement of the injection button causes a corresponding movement of the piston rod until the nut engages an abutment in the housing (1).

Abstract: An adjusting device, and method, used to adjust a dose of a substance to be administered by an injection device, wherein the adjusting device includes a first element and at least one additional element displaceable relative to the first element, the first element having at least two thread pitches which are offset in relation to each other such that at least one thread element of the at least one additional element is only guided into one of the at least two thread pitches of the first element. The invention encompasses a method for making an adjusting device for an injection device, wherein the thread of at least one dosing element is introduced into an associated thread of an additional dosing element, such that a predetermined position ratio between the dosing element and the additional dosing element is established.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: A veterinary syringe comprises a base body for receiving a syringe barrel with a guiding element for a plunger rod that is guided therein so as to be movable in a longitudinal direction. At one end of the plunger rod, a plunger is attached that extends into the syringe barrel. The syringe further comprises a handle and an operating lever. The operating lever is connected to a guiding element that engages with a toothed rack associated with the plunger rod, and with a locking device for the plunger rod that engages with the toothed rack. The locking device acts as a locking slider disposed inside the guiding element and has an opening through which the plunger rod is guided and extends into the toothed rack from below, locking the toothed rack so as to prevent it from withdrawing.

Abstract: A flexible piston rod includes a piston and a row of elements, each having top, bottom, and lateral surfaces, the top surface of one element being connected to the bottom surface of an adjacent element by a hinge that allows the two adjacent elements to pivot from a first position, where a portion of the top surface of one element abuts a corresponding portion of the bottom surface of the adjacent element and corresponding to a rectilinear, relatively stiff configuration of the piston rod, to a second position wherein the top surface of one element is spaced from the bottom surface of the adjacent element and corresponding to a curved configuration of the piston rod. The lateral surface of each element has first and second mutually-opposed cylindrical surface portions incorporating a thread for meshing with a corresponding thread of an actuator for displacing the piston rod longitudinally.

Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base.

Abstract: An end-of-content arrangement for preventing a dose setting member of an injection device to be set to a dose larger that the medicament remaining in the injection device. The arrangement is particular suitable for injection devices operating with non-equistant dose volumes. The arrangement comprises an indentation provided on the housing or on the dose setting and injection member which indentation arrest a stop member when less than one dose unit is left in the cartridge. The stop member is coupled to the dose setting member such that the interaction between the indentation and the stop member prevents a dose larger that the remaining medication in being set.

Abstract: A hand-held power syringe. The power syringe includes a handle with pivotally connected first and second members. The first member is also pivotally connectable to a syringe barrel, while the second member is pivotally connectable to a syringe plunger. These three pivotal connections provide leverage for forcing high viscosity fluids into and out of a receptacle of the syringe barrel. One or both of the first and second members of the handle may be bent to facilitate a user's gripping and movement of the first and second handle members. The power syringe may be used in any suitable injection, infusion, or sample-obtaining application, including angiography and angioplasty.

Abstract: An injection device having an incremental clicking mechanism providing the user with an indication of the number of doses being set. For handling different types of medicaments having different dose volumes in the same type of injection device it is beneficial to provide an additional clicking mechanism which is easy changeable. The clicking mechanism is preferably a curved track provided between the dose setting member and a non-rotatable clicker element.

Abstract: An incrementing mechanism suitable for use in a medical injector device has a driving member rotatably and slidably mounted within a tubular body and arranged to advance an elongate element in one direction with respect to the tubular body. A one-way clutch includes a generally conical surface and a blocking clutch member engageable with the conical surface. Means are provided to disengage the clutch, including a pressure component arranged and biased to engage the clutch member. Rotation of the driving member with respect to the pressure component causes two sets of inter-engageable teeth to ride over each other, which successively lifts the pressure component to disengage the clutch member from the conical surface and then allows the pressure component to be biased to a position where the clutch member engages the conical surface.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base.

Abstract: A dose setting device for a delivery system has a piston rod (6, 9) which successively presses a piston (2) into a cylinder ampoule (1). Doses are set by rotating a second part (9) of the piston rod (6, 9) in relation to a first part (6). The two parts are connected by mating threads so that the total length of the piston rod (6, 9) is increased proportional to the angle of rotation, and a point (18) on the second part is moved away from a stop position fixed in relation to a housing (5) The set dose is delivered when the point (18) is moved back to the stop position. The first part (6) can be axially displaced but not rotated in the housing (5), and the second part (9) can both rotate and be axially displaced. The first part (6) is maintained in abutment with the piston (2) and the second part (9) is coupled to be rotated by a dose setting wheel (20).

Abstract: This relates to an improved delivery system for accurately loading and controlling the delivery of flowable material to a patient. Particularly, the system may be used in the injection of hard tissue implant materials such as PMMA under pressures up to about 4000 psi. The system includes an applicator with a first column having an implant material introduction section adapted to provide for effective loading of the implant material and a second column housing a piston. The introduction section has a larger size than that of a vessel section or bore in which the requisite pressure seal between the piston and bore wall is formed. The first column may include an introduction section flared open to an included larger funnel-like opening or a separate funnel may be used that interfaces with the introduction section to facilitate the introduction of implant material.

Abstract: This injector head 1000 comprises a plunger 20 capable of reciprocating in a direction of movement of a piston 1a in a syringe 1, a plunger drive 500 for converting rotary motion of a plunger motor 2 to linear motion in order to supply reciprocation to this plunger 20, and a safety device 600 as safety means for restraining rotation of a rotary shaft 2a of the plunger motor 2 when the plunger 20 moves beyond a predetermined position. Thus, it is possible to provide a medical injector head attaining miniaturization and simplification of the apparatus while keeping a mechanical safety mechanism.

Abstract: A medication delivery pen is provided having a lead screw with an enlarged portion at a first end thereof and an end longitudinally opposite the first end in contacting engagement with a plunger of a medication cartridge. The lead screw is selectively axially displaceable by a user when selectively administering a predetermined dosage amount of medication for injection into a patient. The medication delivery pen also includes a driver coaxially disposed about the lead screw; and, a reset ring non-rotatably disposed on the driver and axially slidable thereon and therealong. The reset ring is axially movable with respect to the driver when a dosage amount is set by a user of the medication delivery pen. The reset ring engages the enlarged portion of the lead screw upon a predetermined extent of relative axial movement between the reset ring and the lead screw.

Abstract: Apparatus for delivering a viscous liquid to a surgical site employs a conventional syringe having a barrel and a plunger movable axially within the barrel from a withdrawn position to an inserted position. The apparatus includes an internally-threaded sleeve and a substantially cylindrical actuation element. The sleeve is configured to receive the plunger in its withdrawn position, and has an open proximal end and a distal end slot configured for receiving the syringe barrel therethrough. The actuation element has an externally-threaded distal portion dimensioned to screw into the proximal end of the sleeve, and a plunger seat, at the distal end of the actuation element, that bears against the plunger and that pushes the plunger axially toward its inserted position in the barrel as the actuation element is threaded into the sleeve.

Abstract: A syringe driver system comprises a rotatable threaded lead screw shaft and a plunger which directly engages the threaded shaft such that rotation of the shaft drives the plunger into the syringe body. The plunger is formed with a threaded shaft engaging portion in the form of a half nut to engage with and follow the threaded shaft. The syringe driver system further comprises a guide system to secure the plunger in direct engagement with the threaded shaft and to prevent rotation of the plunger. An arm of the plunger stem carries markers useful in determining the near end of infusion. The syringe body carries a marker or markers useful in determining a characteristic about the syringe, such as its volume.

Abstract: An injection device for injection of set does of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting drum. An injection button is coupled to the piston rod with a gear wheel transmission. Axial movement of the injection button causes a corresponding axial movement of the piston rod until the nut engages an abutment in the housing.

Abstract: The present invention provides a novel apparatus for delivering a liquid or gel-like surgical material to a target site within a body cavity. The apparatus is characterized in part by an elongated structural member adapted for engagement with a conventional syringe and cannula assembly. In preferred embodiments of the present invention, devices of the invention further comprise a highly flexible applicator tip which permits application of the surgical material at variable delivery angles and even against gravity. Methods also are disclosed for applying the surgical material to the target site using. devices of the present invention.

Abstract: A drug delivery device comprising a housing (1) with a drug container (2) being provided with delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2). The housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2) and rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism. The one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.

Abstract: An electrically-driven dental injector used in orally injecting such an injection liquid as an anesthetic in dental treatment. Electrically-driven dental injectors includes one having a mechanism for disengaging a pinion (82) from a rack (48) in order to retract a plunger rod (44) upon completion of injection; however, it has heretofore been necessary to manually operate the operating part from outside each time. The inventive electrically-driven dental injector is so arranged that the plunger rod can be manually pushed back directly oupon completion of injection without requiring manual operation, and, to this end, the injector comprises a latch mechanism (84) for engaging/disengaging the ring gear (70) of a planetary reduction gear (50) with/from a casing (52), and an operating rod (94) extending through a support member (20) and functionally cooperating with the latch mechanism (84).

Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.

Abstract: This invention relates to a drug cartridge assembly for use with a reusable body assembly of a medication delivery pen. The drug cartridge is disposable and is in the form of a single integral unit having a generally tubular barrel. Medication is pre-filled into the drug cartridge and is retained therein by an elastomeric stopper or plunger. The plunger is in sliding fluid-tight engagement with a tubular wall of the barrel. A proximal end of the tubular barrel is configured for interconnecting the drug cartridge with a pen body assembly and a distal end of the tubular barrel is configured to securely but releasably engage a needle cannula assembly.

Abstract: By a cylinder ampoule (1), comprising a tubular vessel with a membrane (4) sealingly closing one end and a piston (9) closing the other end, liquid stored between said piston (9) and said membrane (4) can be pressed out through an injection needle (7) piercing the membrane (4) when the piston (9) is pressed into the ampoule (1). The tube is made from a plastically deformable material. A pressure foot (10) on which a piston rod (13) is acting abuts the piston (9), carries a spring plate (11) made from a harder material than is the ampoule (1), is mainly perpendicular to the ampoule (1) axis, and has at least one diameter which is larger than the inner diameter of the ampoule (1) so that edges of the plate (11) abutting the inner wall of the ampoule (1) are deflected away from the piston (9) to form an acute angle with said wall.

Abstract: A threaded syringe provides a mechanism by which a clinician can deliver a viscous fluid through a relatively small lumen and can obtain tactile or audible feedback of delivery. The threaded syringe allows for delivery of more viscous fluids with less force and/or allows for more controlled delivery. The syringe includes a syringe barrel and a sliding member positioned on the proximal end of the syringe barrel. The sliding member has a first threaded hole and a second hole. The sliding member is slidable on the syringe barrel between a first position at which the first threaded hole is aligned with the syringe barrel for precise delivery of a material from the syringe and a second position at which the second hole is aligned with the syringe barrel for filling of the syringe or to stop bleed out.

Abstract: Apparatus for delivering a viscous liquid to a surgical site employs a conventional syringe having a barrel and a plunger movable axially within the barrel from a withdrawn position to an inserted position. The apparatus includes an internally-threaded sleeve and a substantially cylindrical actuation element. The sleeve is configured to receive the plunger in its withdrawn position, and has an open proximal end and a distal end slot configured for receiving the syringe barrel therethrough. The actuation element has an externally-threaded distal portion dimensioned to screw into the proximal end of the sleeve, and a plunger seat, at the distal end of the actuation element, that bears against the plunger and that pushes the plunger axially toward its inserted position in the barrel as the actuation element is threaded into the sleeve.

Abstract: This invention relates to a drug cartridge assembly for use with a reusable body assembly of a medication delivery pen. The drug cartridge is disposable and is in the form of a single integral unit having a generally tubular barrel. Medication is pre-filled into the drug cartridge and is retained therein by an elastomeric stopper or plunger. The plunger is in sliding fluid-tight engagement with a tubular wall of the barrel. A proximal end of the tubular barrel is configured for interconnecting the drug cartridge with a pen body assembly and a distal end of the tubular barrel is configured to securely but releasably engage a needle cannula assembly.

Abstract: A flexible piston rod for an injection device, which piston has the form of a helical spring made from a number of narrowly adjacent turns of windings. These turns provide an external thread fitting into the internal thread of a nut element. When the nut element is rotated, the piston rod is advanced forward, which movement is used to displace a piston inside a cartridge containing a fluid to be expelled. In order to prevent the piston rod from rotating when the nut element is rotated, the helical spring making up the piston rod is provided with a longitudinal spine, which is located at a peripheral area of the helical spring.

Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.