Abstract: A process and a device for pressure controlled manipulation of a fluid (4a), in particular for medicinal applications. The device comprises a receptacle (1a) of variable volume to contain the fluid (4a), a pressure creation device (2a) for producing pressure on the fluid (4a), an opening (1c) for admitting and/or discharging to fluid (4a), a measuring channel (2e) of prescribed cross-section connected to the receptacle (1a), and a buffer (2d) of prescribed volume which communicates with the measuring channel (2e), the measuring channel (2e) and the buffer (2d) being filled with a compressible medium. The pressure creation device is preferably a piston (2a) which can be pushed into the receptacle (1a), the piston being sealed to the inner wall of the receptacle (1a) by a sealing means (2c).

Abstract: A dispensing cartridge especially suitable for use with a hand-held applicator for dispensing liquids having a relatively low viscosity has a chamber and at least one compressible, porous material received in the chamber. Each of the porous materials receives a quantity of a liquid composition. As a piston is advanced in the chamber, each porous material is compressed to cause the composition or compositions to be discharged through an outlet opening.

Abstract: Solid disks of polyethylene oxide are radiation crosslinked to instill viscoelastic memory. The disks are then pierced with a needle, heated, cooled and the needle removed to form disks containing a flow orifice in each which upon contact with water will revert to solid disks. A disk with a flow orifice made as just described when used as a memory flow control valve in a conventional injection device will produce a syringe with a single-use, auto-destruct capability. When the disk is inserted in a retainer in the flow channel of the injection device, a drug/vaccine can be drawn into the syringe and then expelled for a preselected time less than six minutes before the water in the drug/vaccine causes the flow orifice in the disk to close, the disk then reverting to its solid shape due to its viscoelastic memory.

Abstract: An adjustable flow syringe is provided that comprises a slidable plunger within a barrel. The barrel has a flow discharge end wherein a neck is located. The neck has a conduit extending therethrough which has an outlet and an inlet such that the conduit is in fluid communication with the barrel.The adjustable flow syringe includes either a valve insert or a porous insert in the conduit which is configured to adjust the flow rate of a fluid leaving the syringe such that a low amount of manually applied force delivers the fluid in drops. The valve insert is formed from a resilient material and conforms to the contours of the conduit. The valve insert has a portion that extends across the conduit outlet with an opening formed therethrough. The porous insert is formed from a porous material and is configured with a shape corresponding to the shape of the conduit so that fluid passes through the conduit primarily via the pores of the porous insert.

Abstract: In an embodiment, a slit valve catheter has a generally tubular catheter body with an exterior surface exposed to an environment and an interior surface defining a lumen. The catheter further includes a valve which has a protuberance projecting radially from the catheter body.

Abstract: A device for forming a leakproof closure on the terminus of a tubing having an elastic wall. The device consists of a plug insertion tool and a plug. The plug is a elongate member having a convex distal end and a proximal end. The plug insertion tool has a handle portion which is dimensioned to be grasped by a user for manipulation. The distal end of the insertion tool has a rod projecting axially therefrom which is adapted to releasably engage the proximal end of the plug. The plug is dimensioned to fit snugly within the elastically distended lumen of the tubing. In operation, the plug insertion tool is releasably attached to the proximal end of the plug by engagement means such as mating threads and the distal end of the plug inserted into the open end of the tubing and advanced by means of the insertion tool. The intralumenal portion of the plug forms a leakproof seal with the elastic wall of the tubing.

Abstract: An arrangement for controlling the flow of blood between the annulus between a catheter and an elastomeric tube which encases it is provided. The arrangement also controls the ease of lateral movement of the catheter in relationship to the elastomeric tube. The arrangement includes a substantially rigid telescoping tube for supporting the elastomeric tube therewithin. The rigid telescoping tube further includes an inner tube having a pin disposed on the outer circumference thereof; and an outer tube having an opening therein forming a slot, and a plurality of substantially equally spaced stops; a first clamping arrangement for fixing one end of the elastomeric tube to the end of the outer tube furthest from the inner tube; and, a second clamping arrangement for fixing the other end of the elastomeric tube to the end of the inner tube furthest from the outer tube.

Abstract: A syringe assembly having needle isolation features includes an elongate barrel having an open proximal end, a chamber for retaining fluid and a tip portion extending from a distal end of the barrel having a passageway therethrough include communication with the chamber. A valve housing extends outwardly from the tip portion of the barrel having a conduit therethrough in communication with the passageway. A needle cannula having a proximal end, a distal end and a lumen therethrough is provided. The proximal end of the needle is connected to the housing so that the lumen is in fluid communication with the conduit. The housing includes internal valve for allowing liquid under pressure in the chamber to flow distally through the conduit and the lumen while preventing unpressurized liquid in the chamber from flowing through the aperture. The internal valve includes a one-way valve structure for preventing liquid flow through the conduit in a proximal direction toward the chamber.

Abstract: The invention relates to a portable and non-implantable device to enable a patient to self-administer, on demand, successive doses of a liquid while ensuring that the period of time between two successive administrations cannot be less than a reference value. The device has a liquid reservoir formed in a piston which can be pushed in a chamber to expel the contents of the chamber via an injection outlet and which is returned in the opposite direction by a return. The liquid reservoir communicates with the inside of the chamber via a passage formed through the piston and is provided with a flow rate limiter so that the time required to fill the chamber corresponds to a reference value. The invention is suitable for medical applications.

Abstract: In the device for administering implants, which comprises an active substance container with injection cannula and plunger, the plunger is arranged in a plunger channel. The plunger channel merges with continuity into the lumen of the cannula. A holder device (5) for the implant (2) is arranged at the lumen-side end of the plunger channel (3).

Abstract: A method and apparatus for dispensing topical medication. The apparatus consists of a dispenser comprising a piston assembly slidably engaged with a housing, and a nozzle frictionally attached to the housing. The housing comprises an upper reservoir, lower reservoir and nozzle reservoir. The piston assembly comprises a piston attached to a rod, the rod reciprocating within a housing rod aperture, and the piston reciprocating within a housing bore. The upper reservoir is defined by a housing top, the housing bore, and the piston. The lower reservoir is defined by the piston, housing bore, and a lower reservoir floor. The upper reservoir communicates with the exterior of the housing by means of a normally closed upper reservoir valve, and with the lower reservoir by means of a normally open piston valve.

Abstract: Device for mixing a pharmaceutical composition stored in a chamber (44) in said device with an agent to be added shortly before administration to form a preparation to be adminstered. The device should be capable of being shaken without leaking. It comprises a hollow body (2) having an outlet (4) sealed by a removable closure (12) and a plunger (6), which is slidable therein in sealing contact with the inner wall of the hollow body (2). The plunger (6), the hollow body (2) and the removable closure (12) define said chamber (44). An actuating means (22) is connected to the plunger (6) for displacing the same in the hollow body (2). A filling conduit (19) for said agent is connected to the chamber (44). A check valve (30) is associated with the conduit (19) and the chamber (44), which prevents flow from the chamber (44) but permits flow into said chamber through said conduit (19).

Abstract: A needleless dosage transfer system for filling medicating devices such as syringes or needleless cannulas to minimize the likelihood of an unwanted needle stick and to avoid the initial cost of a needle as well as the disposal cost of the needle. A vial has a body portion (20) formed with flexibly deformable walls and defines a blind bore. An opening of the vial includes a tapered section adapted to frictionally fit over a taper of a male luer-type fitting commonly found on syringes and needleless cannulas. By deforming the walls of the vial, fluid is forced from the vial into a syringe. The opening of the vial (10) is protected with a cap and includes a scoreline which, when fractured, defines the opening. The cap to be removed from the vial prior to its use is fabricated as one piece with the vial in order to assure sterile conditions during manufacture and filling. A tab is associated with the cap which lists the ingredients within the vial. The vial also supports an area which lists the vial's contents.

Abstract: A syringe containing drug to be injected, the syringe includes an injection tube, a needle mounted at the front end of the injection tube, a rubber sealing jacket stopper jacketing on the peak of the needle and an injection tube core movably and hermetically put inside the injection tube, which is characterized in that the injection tube core consists of an ampule of cylindrical bottle shape and a piston, the back end of the ampule is closed and at its front end there are a flange and a neck portion, the central through hole of the flange and the neck portion is interpenetrated with the inner cavity of the bottle-shaped injection tube core; the outside top of the piston appears as a cone, and its outside lower part is a cylinder matching the inner wall of the injection tube, while the inside top of the piston appears as an inner cone, and the form of its inside lower part matches the shapes of the flange and the neck portion located at the front end of the ampule; at the cone-shaped top of the piston there is

Abstract: The present invention provides a method and device for draining gastric fluid from a patient. An oral/nasal-gastric tube is provided which includes a gastric inlet, a suction outlet formed for attachment with a suction-drain collection container, a bypass outlet formed for attachment with a gravity-drain collection container, and at least one valve positioned on the oral/nasal-gastric tube. An optional clearance tube is provided for extension between the gravity-drain collection container and the suction-drain collection container so that fluids may be drained, cleared to the collection canister and then may be easily disposed.

Abstract: The invention relates to a safety valve plug to be used in pre-filled syringes, of the kind comprising a cylindrical hollow body into which a coaxial plunger is displaced, projecting outwardly from one of the bases; while a conical portion is defined at the opposite base, the conical portion receiving the injection needle and being called "plugging cone", the valve plug being snug fit inside said "plugging cone" with its end head bearing on the mouth thereof, said valve plug comprising a substantially cylindrical solid body having a conical end portion and the other portion, defining its head, being cylindrical and of a cross section larger than the rest of the body; the cylindrical body having, following said conical end, two faceted faces extending adjacent the head.

Abstract: A needle of an insulin syringe with an exchangeable injection needle and with an insulin ampulla exchangeably connected to the needle is provided and has two coaxial needle portions which are arranged distant from each other. The two needle portions are separated from each other by passage stopping means. The outer needle portion, namely the injection needle, is fastened within a needle supporting body within the needle casing, and the inner needle portion, namely the connecting needle to the insulin ampulla, is arranged within a guide body which is located within the needle casing. The passage stopping means preferably is a flexible membrane or diaphragm with a self-sealing passageway, which acts in such a manner that under pressure a predetermined adjustable amount of insulin fluid is able to pass from one needle portion into the other, and that without pressure action the flexible passage of the membrane locks the flow to the outer needle portion.

Abstract: A special epidural catheter syringe, epidural catheter connector, and continuous epidural tubing connector are provided to provide mechanical lockouts to prevent epidural anesthetic from being injected intravenously and to prevent medications intended for intravenous use from being injected into the epidural catheter.

Abstract: A syringe nasal sprayer includes an elongate barrel having an open proximal end, a chamber for retaining fluid and a tip portion extending from a distal end of the barrel having a passageway therethrough communicating with the chamber. A stopper is slidably positioned in fluid-tight engagement inside the barrel. An elongate plunger rod projects proximally from the stopper and extends outwardly from the open proximal end of the barrel. A spray nozzle extends outwardly from the tip portion and includes a conduit therethrough in fluid communication with the passageway. A distal end of the nozzle includes a spray aperture in fluid communication with the conduit. The nozzle also includes an internal valve for allowing liquid under pressure in the chamber to flow distally through the conduit and through the aperture while preventing unpressurized liquid in the chamber from flowing through the aperture.

Abstract: A stopcock comprises a tubular outer body having at least two radial openings being on the same transverse cross-sectional plane of said body; and a hollow core member snugly fitting into said outer body and having a first open end and a second, closed end, said member being connected to or integral with a handle at said second end; said member having at least one radial bore; and being rotatable within said body between a first state in which said bore is in register with a first of said at least two openings and a second state in which said bore is in register with a second of said at least two openings.

Abstract: An angiographic injector includes a syringe which is connected to a fluid reservoir through a valve which permits radiographic contrast material to be drawn from the reservoir into the syringe during a fill operation. The valve permits air to be expelled from the syringe through the valve during a purge operation, but blocks flow of contrast material from the syringe back to the fluid reservoir. During an injection, the valve blocks flow of contrast material back to the fluid reservoir while the contrast fluid is being delivered under pressure from the syringe to a patient.

Abstract: A fluid container assembly which can be aseptically filled in the field with selected fluids and one which is specially designed for sterile coupling and use with fluid dispensing and delivery devices of the character that embody stored energy sources such as compressible cellular masses and distendible elastomeric membranes that form, in conjunction with a cooperating base, fluid chambers for containing the fluid to be dispensed.

Abstract: A device and method for localized application of a fluid to a small area of skin, which includes an ejection nozzle forming a passage with one or more apertures, a receptacle chamber forming a cavity around the ejection nozzle, the receptacle chamber being configured and affixed to the ejection nozzle such that fluid ejected from the ejection nozzle is capable of being confined within the receptacle chamber, an inflow duct, and an outflow duct. Fluids which may be applied according to the present invention may include escharotic fluids, alpha-hydroxy compounds, exfoliants, cleansing agents, and other medicinal and cosmetic agents.

Abstract: A valve for controlling the flow of fluids through a cannula or catheter made up of a single block piece in the shape of a backward "7" having a head and a stem. As the stem is raised in relation to the hub of the cannula or catheter, the head blocks any flow through the cannula or catheter; as the stem is lowered, the head retracts allowing the flow to continue.

Abstract: This invention is an improved flashback vent. A thin piece of biocompatible material is affixed over the open proximal end of a flashback chamber or a plug in the flashback chamber. This material has a plurality of holes formed therein. Thus, where the flashback chamber is used with an IV catheter introducer needle, blood can enter the flashback chamber and allow air to be vented therefrom without blood leaking from the flashback chamber.

Abstract: A process and apparatus used in manufacturing prefilled, sterile delivery devices such as syringe assemblies. The process includes sealing a syringe container portion at both ends and filling the same through a port provided in the container portion between the two ends. After filling, the port is closed and sealed and the syringe assembly is sterilized to provide a sterile delivery device with sterile contents. A suitable syringe container portion for producing prefilled, sterile delivery devices is also disclosed.

Abstract: A single use syringe in which the single use aspects are accomplished by a lumen spike which is forced into the lumen bore to seal the passageway from the syringe body to the hypodermic needle. Fail-safe characteristics to prevent bypassing the single use provisions are provided by having a frangible area of the endwall holding the lumen break out at a force less than that required to force the lumen spike out of the lumen bore. This aspect can also be used to improve other approaches to single use syringes. The lumen spike can be formed as part of the piston/plunger and the piston/plunger can be a unitary device useful in all syringes.

Abstract: In the device for administering implants, which comprises an active substance container with injection cannula and plunger, the plunger is arranged in a plunger channel. The plunger channel merges with continuity into the lumen of the cannula. A holder device (5) for the implant (2) is arranged at the lumen-side end of the plunger channel (3).

Abstract: A central venous catheter initialization and access system is disclosed for initially flushing and establishing a heparin lock in multiple lumens of a central venous catheter (CVC). The system comprises a plurality of syringes integrally mounted atop a generally planar underlying support sheet in discrete and spaced groups corresponding to individual lumens of a multi-lumen CVC. Each discrete syringe group comprises at least a flush syringe and an anti-coagulant syringe. The flush syringes are pre-filled with saline, and the anti-coagulant syringes are pre-filled with heparin. A multi-position valve assembly is also mounted atop the support sheet. The multi-position valve assembly has a plurality of individual valve inlet ports in fluid communication with the respective individual syringes, and a separate valve outlet port for each discrete syringe group. The valve outlet ports have connectors which mate with the lumens of a CVC.

Abstract: An intravascular catheter comprises a proximal housing carried on a tubular catheter body. The housing carries a slit, elastomeric partition valve which comprises a barrier wall positioned to block flow through the lumen of the catheter body, while permitting an elongated member such as a catheter to pass through the valve into the lumen without substantial back leakage of blood. The slit comprises a plurality of intersecting radii which rotate in spiral manner as the slit extends through the barrier wall to define a slit shaped of the intersecting radii of a first diameter on one side of the barrier wall. The slit spirals down to a lesser diameter on the other side of the barrier wall. Thus, advancement of a catheter or the like through the valve is facilitated, and back-leakage through the valve around the catheter is suppressed. Specifically, the intravascular catheter of this invention may be a catheter sheath introducer.

Abstract: A hemostatic safety catheter-cannula assembly for the prevention of contamination by blood during vascular insertion includes a catheter-cannula having a flexible catheter-cannula tube connected to a base that includes a one-way valve member biased to normally prevent fluid flow through the catheter-cannula.

Abstract: An evacuator particularly suited for irrigation and removal of tissue from a body cavity such as the bladder. The evacuator includes a positive displacement syringe with a hollow plunger for pumping a sterile solution into the bladder for irrigation and for withdrawing the solution and entrained tissue from the bladder and urethra. Internal valving controls the order of flow within the evacuator so that, as the solution circulates through the evacuator, tissue is filtered from the solution and captured in a collection container.

Abstract: An apparatus (10) for preparing and administering a dose of a fluid mixture for injection into body tissue includes a syringe assembly (20), a valve (30), a vessel (60) containing a pressurized fluid, and an infusion cannula (70). The valve (30) has a first passageway (98), a second passageway (99), a third passageway (100), and a fluid flow director (96). The fluid flow director (96) selectively directs fluid flow between any two of the passageways, and simultaneously shuts off flow to the third. The first passageway (98) is connected to a fluid receiving reservoir with the syringe assembly (20), the second passageway is removably connected to the infusion cannula (70), and the third passageway (100) is connected to the vessel (60).

Abstract: An injection syringe useful in the medical arts for injecting high viscosity fluids or pastes, particularly in endoscopic applications. The syringe includes a force multiplying mechanism to infuse viscous medicaments such as collagen or polytetrafluoroethylene paste, with a controlled metering action. The force multiplying mechanism is provided by the combination of lower piston cylinder chamber that intersects with an upper cylinder chamber, wherein the piston is connected to a piston advancing means on a lever pivot arm.

Abstract: A fluid sampling method in which a variable volume chamber between a needle site and a syringe creates a negative pressure at the tip on its removal from the needle site to reduce the exposure to liquid at the time of removal.

Abstract: A multipharmaceutical delivery system, such as a syringe (2) or a topical pharmaceutical applicator, suitable for a simultaneous delivery of a mixture (124) of two or more mixed pharmaceuticals (52, 120) in selected amounts and proportions, includes a body (4, 180) with first and second variable volume reservoirs (24, 26), containing the first and second liquids or other flowable materials, such as creams and salves. The reservoirs are connected to a variable volume accumulator chamber (31) through check valves (28) to permit liquid to flow from the reservoirs into the accumulator chamber but not the reverse. A delivery head, such as a needle assembly (78) or a spray nozzle assembly (196), is selectively fluidly coupled to the accumulator chamber by an exit path (106, 202) formed in the body.

Abstract: An improved blood drawing syringe characterized by a barrel having a hollow cylindrical bore with an open rear end and a reduced diameter front end for the attachment of a needle, a pushrod disposed for slidable movement within the barrel, a piston attached to the forward end of the pushrod and having a circular disc with spaced apart forward and rear perforated faces enclosing a filter disposed between the faces, a sealing flange disposed around the periphery of the disc sized and dimensioned to fit slidingly within the cylindrical bore of the barrel and a flexible seal abutting the rear face of the disc and adapted to selectively cover the perforations in the rear face of the disc as a function of forward or rearward air pressure on the flexible seal.

Abstract: A syringe assembly having a syringe has an outlet opening and a tube having an inner end hermetically sealed over the outlet opening and an outer end. Thus any contents of the syringe can flow unimpeded via the outlet into the tube and vice versa. A seal hermetically closes the outer end of the tube. Such a syringe assembly is filled from a medical-liquid-holding container also having an outlet opening provided with a respective such tube whose outer end is similarly sealed. The syringe is filled by first unsealing and joining the outer ends of the tubes to each other in a sterile docking procedure, then aspirating the medicament through the unsealed and joined ends and resealing the tubes together, and finally cutting the tubes apart where they are sealed together to form two new seals on the tube outer ends.

Abstract: The present invention relates to an aspirator for aspirating materials to be removed within the eyeball. The materials are an infusion or the viterous body.A conventional aspirator permits no easy provision of an arbitrary pressure. In accordance with the present invention, a pressure adjusting unit (90) is disposed to connect an accommodating unit (100) to the air through an opening (96) of a variable size.For such a conventional aspirator, it is required that aspiration should be interrupted as a bottle is full with the removed materials. For the present invention, there are provided a first accommodating unit (2100), a second accommodating unit (2101) and a third accommodating unit (2102). The third accommodating unit (2102) has a capacity larger than each of the first and second accommodating units (2100, 2101). These accommodating units are connected.Furthermore, such a conventional aspirator may not ensure a safety in surgery.

Abstract: Inside a syringe (1) slides a plunger (2) which bears a joint (4) sliding sealingly over the internal wall of the syringe. The flexible membrane (6) of the joint (4) fixed to the end of the plunger (2) bears a closing component (25, 27) which follows the movement of deformation or displacement of the membrane through the effect of the pressure built up during the injection stage, but which is retained by immobilizing strips (17) in a position in which it opens the orifice, breaking the seal between the top and the bottom of the joint, as soon as the membrane returns to its initial position.

Abstract: A fluid sampling device in which a resilient element held between an actuator and a probe drives the tip of the latter sealingly against a source of fluid, and creates a negative pressure at the tip on its removal from the source.

Abstract: In a multi-chamber container (1), in which is accomodated at least one chamber partition wall (4) movable through the two chambers and having at least one orifice (8) which makes a connection between the two adjacent chambers (2, 3) and interacts with a shutoff member and which can be opened and closed via a tappet (10) actuable from outside, the chamber partition wall (4) sealed off on the inside of the container being movable through the container (1), according to the invention the orifice (8) in the chamber partition wall (4) is equipped to receive a thread of a valve spindle (23) which can be screwed in by means of the tappet and which terminates at a stop (24) interacting with one side (26) of the chamber partition wall (4) and at a valve plate (32) formed by a ring (32) of the rod and ensuring sealing on the opposite side (35) of the chamber partition wall (4), the valve plate (24) and the stop (32) being layable onto their seats (27, 23) as a result of an alternating rotation of the rod (10), and the

Abstract: An apparatus for selectively providing irrigation or evacuation to a patient during surgery which includes valve arrangements to prevent reflux of fluid and the drawing of irrigation fluid from a reservoir in the event the patient line becomes blocked.

Abstract: An infusion catheter adapter and cap assembly, the catheter adapter has a housing with an input, an output and a side port, normal to the housing axis, which has a cap. The cap is fixedly attached to the housing by a living hinge with a retaining knob. The retaining knob on the living hinge conjugates with a groove on the housing. The groove is formed as a transverse channel defined by two opposing locking fingers. The position of the retaining knob in the groove is further ensured by a recess on the knob which conjugates with a peak in the groove to center and lock the retaining knob in the groove.

Abstract: Patient controlled analgesic (PCA) infusion apparatus and method are disclosed, in which a liquid desired to be self-infused into a patient is controllably supplied from a positively pressurized supply reservoir to a lower pressure dose chamber of a patient operable syringe from which the patient may expel the liquid and infuse such into a suitable infusion site, as through a cannula inserted into the patient, the supply of liquid from the reservoir to the dose chamber being controlled by a flow control metering tube assembly, including a connecting tube with a flow-restricting metering rod disposed therein and of a selected effective length such that the combined flow impedance of the flow path formed by the overall flow metering tube and rod provide a selected flow rate for a reference fluid and reference pressure differential.

Abstract: A fluid-communicating device with valve function comprising a tubular body having an inlet and an outlet, and a blocking body inserted in the tubular body is disclosed. The blocking body comprises a plug portion, and a supporting portion on which a diameter-enlarging portion for enlarging an inner wall of the tubular body is provided. The plug portion of the blocking body is placed in a seal portion of the tubular body to close the tubular body and to prevent the passage of fluid. In use, a tip of a syringe and the like is inserted into the tubular body, so that there is formed a clearance between the outer wall of the plug portion and the inner wall of the seal portion. Fluid passes through the clearance and a fluid passage formed longitudinally on the supporting portion or on an inner wall of the tubular body.

Abstract: A catheter introduction syringe for the introduction of a catheter or catheter guide wire into a patient's body, the catheter introduction syringe comprises a hollow syringe barrel including a fluid chamber, a plunger movable between an advanced and retracted position slidably disposed within the fluid chamber, a guide passage formed longitudinally through the hollow syringe barrel and the plunger, the guide passage including an aperture disposed within the fluid chamber and a valve assembly disposed in operative relationship relative to the guide passage to prevent passage of fluid through the guide passage during flushing or aspirating of the catheter introduction syringe or during the introduction or withdrawal of a catheter or catheter guide wire through the guide passage and to permit fluid to flow from the patient's body into the fluid chamber through the aperture the guide passage being configured to maintain the catheter or catheter guide wire in a substantially straight configuration while the cathet

Abstract: A syringe comprising a barrel with means for positioning a needle at a forward end thereof, a plunger displaceable within the barrel, sealing means to maintain the integrity of a dispensing chamber forwardly of the barrel, wherein the plunger has associated disabling means to render the sealing means ineffective after a first use of the syringe.

Abstract: An aspirator for removing a body liquid from a body cavity comprising a cylindrical receptacle having a top wall comprising a flap valve, and an aspirating tube, one end of said aspirating tube being connected with the upper part of the receptacle and the other end having such a shape that it can be inserted into the body cavity, said receptacle being partly surrounded by a cylindrical cap-shaped member having a top wall including a flap valve, the cap-shaped member having such a shape that an axial displacement of the cap-shaped member relative to the receptacle produces a vacuum in the space between the cap-shaped member and the receptacle.The aspirator is more compact and of a simpler construction than the corresponding prior art aspirators.

Abstract: A single use syringe .[.having.]. .Iadd.has .Iaddend.an interacting piston and cylinder which cooperate to define a variable volume working space.[.,.]..Iadd.; .Iaddend.the syringe includes a valve body located in the chamber so as to divide the chamber into a first and second sub-chamber, .Iadd.and .Iaddend.the valve body has valves which permit a liquid to be initially drawn into the syringe and then injected, but prevent a subsequent liquid being drawn into the syringe. .Iadd.A valve for the syringe is also claimed. .Iaddend.