Abstract: An indwelling needle assembly has a hollow outer needle fixed to an outer needle hub, an inner needle in the outer needle and fixed to an inner needle hub, and a protector. A step section of the outer needle hub serves as a speed reducer that reduces the speed, in the direction of the flow path axis of a main pipe, of a liquid portion flowing in the flow path, the portion flowing along that portion of the inner surface of the main pipe located on that side of the main pipe on which a branch flow path is located. The step section has an opening in the inner surface of the main pipe located at a position corresponding to a front end opening of the branch flow path. The step section forms a space between the opening and the front end opening of the branch flow path.

Abstract: Apparatus administers dental anesthetic to intraligamentary tissue with a drive unit and handpiece with injection needle connected by flexible tube to the unit. The drug is passes to the tissue at an instantaneous pressure at the needle tip that varies due to placement. A minimum threshold pressure is desired for administering the drug to the tissue. A practitioner moves the handpiece to insert the needle tip near the intraligamentary tissue and the instantaneous pressure is sensing or calculating. An auditory ascending signal indicates when the instantaneous pressure is rising, and when the instantaneous pressure reaches the threshold pressure a perceptible auditory specific signal indicates the practitioner has moved the tip into intraligamentary tissue. The tip is then maintained for supplying a selected dosage of the drug. Another auditory signal notifies the practitioner that the instantaneous pressure is declining or fluctuating before reaching the minimum threshold pressure.

Abstract: A flushable catheter assembly having features to enable selective activation of fluid flow through the catheter assembly is disclosed herein. A septum is placed within the catheter adapter of the catheter assembly and includes a pathway that is closed prior to being biased open via a septum activator also positioned within the catheter adapter. A plurality of air vent channels is interposed between the septum and the inner surface of the catheter adapter to permit “flashback” of blood during insertion of the catheter into a patient. The septum activator is advanced through the pathway of the septum as a coupler is attached to a proximal opening of the catheter adapter.

Abstract: The present invention provides an absorbing pad for indicating saturation. The pad comprises inter alia from at least one absorbent body, at least one saturation sensor embedded within said absorbent body and at least one saturation indicator connected to said saturation sensor, embedded within said absorbent body wherein said indicator is adapted to provide information to the user as to the degree of saturation of said pad without removing the pad from its application.

Abstract: An inflation syringe having an improved display and method of displaying pressurization information. More particularly, the present invention relates to methods and apparatuses for providing both numeric and non-numeric indications of an inflation pressurization associated with an inflation syringe. According to one embodiment of the present invention, a progressive non-numeric display is provided for displaying the pressurization of the inflation syringe along with numeric indicators of the pressurization. The progressive display includes a plurality of indicia corresponding to a range of inflation pressurization values. The indicia are actuated to indicate inflation pressurization and to allow the practitioner to not only easily monitor the general intensity of the pressurization but to monitor changes in the pressurization without needing to interpret numerical values.

Abstract: A fluid flow rate control system and method comprises a capillary tube having a proximal end that projects into a chamber with a cross-sectional area that is larger than or equal to the fluid supply tube's cross-sectional area. The inner cross-sectional area of the capillary tube is configured less than the inner cross-sectional area of the chamber. The chamber has a volume large enough to slow the fluid conducted to it by the upstream fluid line to permit contaminants to fall out of solution. In another aspect, a sleeve is used to mount the capillary tube into the chamber. The sleeve provides a mounting surface for tube segments from the pump and downstream of the capillary restrictor.

Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.

Abstract: A hub for a sheath, catheter, or other tubular device includes a tubular hub body including first and second ends, and a lumen extending therebetween and surrounding a central longitudinal axis, the lumen having a first cross-sectional area sized for receiving a medical device therethrough. A valve is secured within the lumen that includes an elastomeric valve body including a passage extending therethrough between front and rear surfaces thereof and offset from the central axis. The valve body defines a second cross-sectional area larger than the first cross-sectional area in a relaxed state in which the passage defines an oval shape, and is secured within the lumen in a compressed state in which the passage is compressed to a closed configuration for sealing the passage from fluid flow. The passage is resiliently expandable to accommodate receiving an instrument therethrough while providing a seal around the instrument.

Abstract: Pneumoperitoneum needles for providing and/or insufflating a corporal and/or abdominal cavity are provided. The pneumoperitoneum needle can include a housing, an elongate tubular body extending from a distal surface of the housing, and an elongate hollow tubular rod slidably received within the tubular body. The tubular body preferably includes a passage formed therethrough for connection to a gas administration system. The tubular rod preferably includes a blunt distal end defining an opening, and a proximal end portion defining an opening formed therethrough.

Abstract: A medical valve having a close mode and an open mode includes a housing having a proximal end, a distal end, and an interior. The valve also has a valve mechanism within the interior. In illustrative embodiments, the valve mechanism has a gland member and a lifter member. The lifter member moves the gland member toward the proximal end of the housing as the valve transitions from the closed mode to the open mode.

Abstract: A collapsible valve comprising a first portion with at least one dimple in a side thereof, and a second portion, the second portion being narrower than the first portion and arranged along an axial dimension of the first portion, the second portion including a cut therein.

Abstract: A fluid control device is characterized in that the device is structured of a hollow first fluid path (21) and second fluid path (22), a housing portion (1) formed between the first fluid path and the second fluid path and having a hollow portion with a cross-sectional area larger than cross-sectional areas of both fluid paths, and a valve member (3) that has a main body (31) and a projection portion (32) that are installed in an opening portion where the first fluid path is connected to the hollow portion and that is formed of an elastic material. The fluid control device enables the circulation of liquid when the pressure of liquid flowing from the first fluid path toward the second fluid path is more than a predetermined level. The fluid control device enables accurate and safe measurement of pressure including blood pressure, and, when flushing operation of an infusion circuit etc.

Abstract: A luer connector including a housing with first end including a male luer tip and a second end. The connector further includes a rigid valve member having a first opened end and a second closed end and a retaining member configured to couple the valve member and the housing. The housing further includes a rigid conduit positioned within the housing and in fluid communication with the second end of the housing, the rigid conduit adapted to engage the first opened end of the valve member. The housing including a first internal volume when the valve member is in a first position and a second, smaller volume when the valve member is in a second position.

Abstract: A luer connector comprising a housing with a hollow bore having first and second ends. The hollow bore also has a male luer tip and a tapering interior surface. The luer connector also comprises a rigid valve member configured to at least partially extend through the housing. The valve member has a first opened end and a second closed end. The valve member also comprises a passageway within the valve member and an outwardly extending flange near the second end adapted to seal the hollow bore at the second end of the housing when placed in contact with a tapering interior surface of the housing. The valve member further comprises at least one opening near the closed end of the valve member extending outward from the passageway through the valve member and at least one strut attached to the valve member. At least a portion of the strut extends substantially parallel to the central axis of the valve member.

Abstract: A valve that is adapted to control the flow rate of fluid flow from an implantable pump or other fluid delivery device is provided. In general, the valve includes a multi-lumen member that is adapted to receive fluid-flow therethrough, and a restrictor member that is coupled to the multi-lumen member such that the restrictor member is effective to selectively restrict at least a portion of one or more lumens in the multi-lumen member to thereby adjust the flow rate of fluid flowing through the multi-lumen member. The valve can be built into an implantable drug pump to control fluid flow exiting the pump, or alternatively the valve can disposed within a catheter or otherwise coupled to an outlet port in an implantable drug pump to control the flow rate of fluid exiting the drug pump.

Abstract: A portable drug delivery system (10) includes a remote unit (14) which serves as a wireless monitor for a drug delivery device (12). Programming of the drug delivery device (12) can be achieved by use of the remote unit (14), but requires tactile intervention by the user with the drug delivery device, thereby avoiding inadvertent or unauthorized changes to the drug delivery settings via the wireless unit. Also disclosed are configurations for receiving and retaining a drug cartridge (42) within a disposable unit (40) of the drug delivery device, and a kit providing user-selectable form factor for the infusion set used with the drug delivery device, allowing the user to select either an integrated infusion set (112) or an external infusion (106) set for each session of use.

Abstract: An adaptor for discriminating connection of an oral tip having a length greater than 0.50 (12.70 mm) to a feeding line and for preventing sealed connection with a standard semi-rigid luer tip having a length less than or equal to 0.50 in (12.70 mm) is disclosed. The adaptor includes a duckbill valve spaced at least 0.50 in (12.70 mm) downstream from a first open end of the body such that when an oral tip is fully inserted into a connection port, the oral tip engages valve flaps of the duckbill valve and opens the valve, and when a standard semi-rigid luer tip is fully inserted into the connection port, the standard semi-rigid luer tip does not contact the valve flaps and the valve flaps remain in a closed position.

Abstract: A cassette insertable into an irrigation or aspiration machine for endoscopy includes an irrigation or an aspiration tube and a support provided with one or two inlet plugs and one or two outlet plugs where two tubes form an elbow to be connectable to the inlet or outlet plugs in an input and output direction of motion, respectively and to form an irrigation or aspiration pumping area in the input and output direction of motion. The support includes a T-shaped guide according to the head of the T for protecting the elbow of each tube and according to the length of the T body in a slot guiding the tube in the output direction. The T-shaped guide extends between one or two inlet plugs to form the irrigation or aspiration pumping area on both sides of the slot between each inlet plug and the head of the T.

Abstract: Flow regulator for the infusion of medicaments, comprising, in succession, a substrate (1), a channel (5), a spacer (3) and a membrane (4), the latter having at least one hole (6) communicating with the channel (5), characterized in that the regulator is produced from at least two separate elements (1-4), the first element comprising the membrane (4) and the second element comprising the spacer (3).

Abstract: A peripheral catheter having a catheter tip diffuser for reducing an exit velocity of an infusant within the catheter. Pluralities of diffusion side holes are provided on the tip portion of the catheter. Some examples further include pluralities of annularly arranged, staggered diffusion holes provided on the tip portion of an intravenous catheter to streamline infusant issued from the diffusion holes. An inner surface of each diffusion hole is further angled relative to the inner surface of the catheter lumen such that an infusant within the lumen exits the catheter though the diffusion holes at an angle less than 90°.

Abstract: A connector for joining ends of two conduits is described, the connector comprising: a male connector portion and a female connector portion, both portions having conduit connection means for the connection of a conduit to each portion; engagement means to hold the male and female connector portions in fluid flow establishing connection when connected together and valve means associated with said female portion.

Abstract: A drug delivery system provides for mixing various drugs in an optimally controlled manner, for using flow controllers to guide multiple drugs into a single or into multiple catheters, for enabling a single lumen catheter to treat a specific region with several drugs, for allowing for dilution of a concentrated drug in order to both increase the time between refilling and also for providing any concentration of a drug that might be desired, for using a buffer fluid to deliver exact amounts of several drugs from the same catheter or to separate several drugs within a single catheter, for using external fluid present in the human body either as a diluent or buffer fluid, and for providing for a drug testing/filler apparatus to be used prior to implant to ensure proper function and easy means of filling multiple reservoirs with different fluids, and also after implant for refilling operations.

Abstract: A sprayer includes a nozzle through which gas is to be ejected with positiveness and uniformity. The sprayer is provided with a nozzle having inner tubes through the interior of which liquid is to pass and an outer tube receiving the inner tubes therein and allowing gas to pass through a space defined with the inserted inner tubes. The inner tubes have respective liquid orifices through which liquids are to be ejected. The outer tube is arranged therein with the liquid orifices and a gas orifice for ejecting gas. When the nozzle is viewed from front, the outer peripheries of the liquid orifices each assume a circular form while the inner peripheries of the gas orifices are differently shaped to provide plural point contact between the outer periphery of the liquid orifice and the inner periphery of the gas orifice.

Abstract: The invention relates to a locking mechanism for adjustable systems for delivering a specified dosage of a substance. The delivery system can be used to deliver, for example, a drug or a nutritional supplement to a human or veterinary patient or for delivering, for example, fertilizer in agricultural use.

Abstract: Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components.

Abstract: The present invention relates to a device (2) for cell therapy, said device being designed to be applied on a living tissue and having at least a tight preferably biocompatible first wall (22), designed to form a cavity (24) between said wall and said tissue, and further comprising means (7) to feed a healing substance in said cavity.

Abstract: A coupling device for connecting two ends of respective tubular members, allow the opening and the closing of a first tubular member and the simultaneous engagement of the two tubular members, as to prevent pollution, includes: a first case housing a first end of a respective first tubular member, comprising closing means of said first end; a second case, wherein a flexible terminal section of a respective second tubular member is received, comprising means for driving a second end of said second tubular member from a retracted position to a engagement position into said first end and vice versa; and means for reversibly connecting said first and second cases at a respective coupling port thereof, defining a single sealed environment; wherein the engagement and the disengagement of said second end and the automatic mechanical activation and deactivation of said closing means for opening and closing said first end.

Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the device reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the device reservoir to the patient.

Abstract: Low profile adaptor for use with a medical catheter, such as a gastrostomy feeding tube. In a preferred embodiment, the adaptor comprises a body having a lower portion and an upper portion. A first channel is provided in the lower portion, and a second channel is provided in the upper portion, the first and second channels being perpendicular to and in fluid communication with one another. A generally cylindrical stem is coaxially positioned within the second channel, the stem being rotatably mounted about its longitudinal axis. The stem is hollow and has an open front end, a closed rear end and a hole in its side wall, the hole being rotatably alignable with the first channel. To facilitate rotational alignment of the hole with the first channel, a stop is formed on the exterior of the stem, the stop being engageable with a surface positioned within the second channel. The front end of the stem is recessed relative to the front end of the second channel to prevent unwanted rotation of the stem.

Abstract: Distinctive components that enable high-throughput, whole-animal screening are described. These components can be used individually or in various combinations. A staging chip strains off the excess fluid that the input animals are immersed in, increasing their density (number of animals in a given volume) and rapidly bringing them close to other fluidic components. A microfluidic sorter is adapted to isolate and immobilize a single, physiologically active animal in a selected geometry. A multiplexed micro-chamber chip receives single animals and the microchamber chip includes individually addressable screening chambers for imaging, incubation and exposure of individual animals to selected chemical compounds. An imaging structure generates sub-cellular, high-resolution images of the physiologically active animals. A well-plate interface chip is used to deliver elements from a compound library to a single output of the chip.

Abstract: A dose delivery device is disclosed where a dose can be set by rotating a dose setting member, whereby a push button is elevated from one end of the device a distance proportional to the set dose from a position fixed relative to the housing, and where the set dose can then be injected by pressing the push button back to its non-elevated position, through which motion a piston rod will move the same or a different distance due to a gearing mechanism being provided between the push button and the piston rod, where the gearing mechanism includes at least a first and a second thread on one or more parts that are rotationally coupled to each other, the first thread engaging a driver, the second thread engaging an element rotationally locked to the driver, one of the threads of the gearing mechanism being left-handed and the other one being right-handed.

Abstract: An apparatus and method for preventing free flow through an infusion set utilizes an occluder disposed within the infusion set to selectively prevent flow therethrough. The occluder may be responsive to a pressure differential within the infusion set or may respond to compression of the infusion set. The occluder may also be configured to allow flow when the infusion set adjacent the occluder is moved sideways relative to the occluder or maintained at an angle relative to the occluder. When a pair of occluders are used in sequence, an in-line pump may be formed.

Abstract: An emergency multi-medication pump injection system is designed for use in rapidly and automatically calculating and administering multiple medications in an emergency setting. The system includes a compact, portable housing comprising a plurality of medication ports, each port configured to receive a corresponding ampoule containing a corresponding medication. The system further includes at least one pump on or within the housing for dispensing a calculated dosage amount of one or more medications from the ampoules, at least one delivery tube for conveying the medication(s) from the system for delivery to the patient, and safety means for ensuring that each ampoule can only be installed in a port to which the particular ampoule corresponds. The pump injection system may include data inputs for inputting data relating to patient weight, medication concentration, medication dosage, and the like.

Abstract: A guide device (1) for introducing at least a surgical instrument internally of an organic cavity (2), in particular a vascular cavity comprises a guide body or guide catheter (3) which is substantially hollow and flexible and exhibits an open directing end (8) which is transversal. The device comprises an elongate and flexible guide element (9), which is slidable internally of the guide body (3) to define an advancing guide for the guide body (3). The device (1) also includes means for stabilising (10) for easily piloting the directing end (8) with respect to the transversal cavity (2b) and for advancing the guide catheter. The means for stabilising are defined by a stabilising opening (11) and by an elongate and flexible stabilising element (12) which internally engages the guide body (3) and exits therefrom through the stabilising opening (11) along the cavity occupied by the guide body (3).

Abstract: A dialysis valve includes a tube attached between an artery and a vein which, when elongated, simultaneously narrows in diameter at least one location. The narrowed portion of the tube decreases the volume and velocity between the arterial and venous side of the patient to prevent damage or intimal hyperplasia on the venous side between dialysis treatments. When the valve is opened for dialysis, an unrestricted blood flow exists between the arterial and venous side, permitting a controlled, open blood flow during dialysis.

Abstract: A liquid coinjector is provided in which one or more connection ports may be connected to an outlet port and in which a valve body is provided for selecting the connection arrangement, the valve body being movable in an axial direction within a chamber of a main body.

Abstract: A device for delivery of medicament, which device comprises an elongated housing; a container (4) mounted within said housing and adapted to contain liquid medicament; a stopper slidably arranged within said container; and actuating means comprising a resilient member (60), a driving means (50) having one end connected to the stopper and a second end being operably connected to the resilient member, retaining means (40) for releasably retaining said driving means in a first position where said resilient member has an accumulated energy, and activating means operably connected to said retaining means for releasing said driving means to a second position, upon actively operation by an user, such that said accumulated energy is transferred to the driving means for driving the stopper a predetermined distance within the container whereby the medicament within said container i delivered characterized in that the resilient member is a variable force spring adapted for generating a predetermined sequence of at least

Abstract: An administration feeding set for use with a flow control apparatus to deliver fluid from at least one fluid source to a patient. The set includes tubing for flow of fluid along a fluid pathway and a mounting member on the tubing adapted to engage the flow control apparatus. The mounting member has at least two receiving portions co-axial with the fluid pathway. The set also includes one or more identification members selectively positioned on one or more of the at least two receiving portions of the mounting member to permit identification of the administration feeding set as having a particular functional configuration different from another functional configuration.

Abstract: A vascular cannula assembly has a cannula, a tube dilator, a supporting helix and an inflatable cuff. The cannula has a distal end, a proximal end, a passage and a drainage segment. The drainage segment has multiple draining apertures communicating with the passage. A valve mounted on the distal end of the cannula can prevent air from entering the cannula. The tube dilator is selectively mounted in the passage and has a leading end and a handling end respectively protruding from the distal end and proximal end of the cannula. The supporting helix is mounted in the passage against the cannula. The inflatable cuff is mounted around the cannula between the distal end and the drainage segment. The side tubing is connected to the inflatable cuff. Since the inflatable cuff can be inflated to occlude blood draining from vena cava, use of the vascular cannula assembly can prevent injuries by snaring or looping of vessels during surgical procedures for cardiopulmonary bypass.

Abstract: A system and a method for delivering fluid to and sensing analyte levels in the body of the patient are disclosed. The system includes a dispensing apparatus configured to infuse fluid into the body of the patient and a sensing apparatus configured to be in communication with the dispensing apparatus and further configured to detect a level of analyte concentration in the body of the patient upon diffusion of the analyte into the fluid to be dispensed by the dispensing apparatus.

Abstract: A safety device is presented for securely stowing a double sharp-ended needle. The device comprises a tubular adapter with a longitudinally-elongated channel. A needle holder is located in the channel to move from a distal orientation, in which one needle end projects from a distal adapter opening, and a proximal orientation, in which both needle ends are enclosed within the adapter body. A top plate transitions from a distal orientation, in which the plate is distal from a proximal adapter opening, and a proximal orientation, in which the top plate obstructs the proximal adapter opening. An actuator plate is attached to the adapter body to transition from a first position where the actuator plate retains the needle holder and top plate in distal orientations, and a second position where the needle holder and top plate move to proximal orientations.

Abstract: A gravity bolus feeding device having a cylindrical body with and intake valve to control or prevent flow of fluid through the feeding device. The device also has a check valve to receive fluids expelled from the patient back into the feeding device. The check valve allows such fluids to rejoin the fluid path and be re-fed to the patient, while allowing air to vent. A burp baffle for use with this or another feeding device to prevent spillage or splashing, while taking in or venting air. The burp baffle has a bottom section which snugly fits into the device, with a notch or opening near its outer periphery, allowing fluid to pass. A center section connected to the bottom section allows fluid to flow around it and into an opening generally opposite the notch. A top section covers the feeding device, and has a hole that allows fluid to vent out the top of the feeding device.

Abstract: An administering device for a fluid product includes a product receptacle that accommodates the product to be administered, a fluid reservoir for a driving fluid, a driving means, a product chamber, and a fluid connection. The product receptacle includes an opening at a forward end and a product stopper at a rear end. The driving means acts upon the fluid reservoir, the pressure chamber adjoins the product stopper while the fluid connection is located between the fluid reservoir and the pressure chamber, and the driving means acts upon the fluid reservoir in such a way that the pressure chamber is impinged upon by pressure which affects the product stopper and the product is discharged from the product receptacle.

Abstract: A vascular access device for communicating with the vascular system of a patient may include a status indicator. The status indicator may detect and signal that a period of time has elapsed in relation to the use of the vascular access device.

Abstract: The present invention provides a device (11) for tube feeding, The device (11) comprises a delivery means (11) such as a tube for delivering food, medicines and other fluids to a patient's stomach. The delivery means (11) has a first portion (27) which is received in the patient, the first portion (27) having a maximum cross section substantially equal to or smaller than the aperture in the patient through which the first portion enters and exits so that the delivery means can be removed from the patient with minimal injury thereto, The device (11) also comprises a retaining means (19) to retain the tube in a desired position.

Abstract: Infusion catheter systems and methods are described herein that incorporate flow restrictors to balance flow to multiple target sites serviced by delivery catheters. Fluids may be delivered to the target sites using multiple separate delivery catheters or through multiple separate lumens located in the same delivery catheter. Flow balancing may be performed between multiple catheters that are fed from a single fluid source, between multiple separate lumens in a single delivery catheter that are also fed from a single fluid source. Multiple catheters may be fluidly connected to one or more flow restrictors housed within an anchor or in another embodiment, a catheter may be fluidly connected to a restrictor housed in one anchor and another catheter fluidly connected to a second anchor wherein each of the restrictors is also fluidly connected to a single fluid source.

Abstract: A drug delivery device may include a drug reservoir configured to contain and controllably deliver a fluidic drug. A tube may be configured to deliver the fluid from the drug reservoir through a lumen in the tube to another location. A valve wholly within the lumen of the tube may regulates the flow of the fluid through the tube without substantially diverting the direction in which the fluid flows through the tube. The valve may contain only a single member which moves during operation of the valve. The valve may be configured to regulate the flow of fluid in a bandpass manner by allowing fluid to flow through the valve only when the pressure of the fluid is above a minimum and below a maximum. The valve may be held in place within the tube solely by frictional force between the valve and a wall of the tube.

Abstract: A valved connector configured to control the leakage of bodily fluid from within a patient. The valved connector including a seal positioned within a lumen of the body of the valved connector. The distal end of the valved connector is adapted to permit access to, or coupling of an apparatus, which is placed in fluid communication with the volume of bodily fluid. A proximal end is adapted to be threadably coupled to a secondary device. The needless connector valve being configured to be openable by a dilator or post of an apparatus which is connected to the proximal end of the needleless connector. In the event that a luer coupler or other secondary apparatus is not available, a needle, cannula, trocar, or other instrument can be threaded through the main lumen of the valved connector opening the valve and allowing the passage of fluid directly through the needle, trocar, cannula, or other instrument.

Abstract: A device for closing lines for administering medical or pharmaceutical fluids from containers and the like, comprising: a first tubular body and a second tubular body, which are mutually associated and able to move axially by sliding and/or rotating with respect to each other; a valve element for adjusting the flow of the fluid formed inside the first and second tubular bodies, the relative movement of the first and second tubular bodies being adapted to move the valve element from a closed configuration for blocking the flow of the fluid to an open configuration for feeding the fluid; elements for limiting the relative rotation between the first and second tubular bodies which are monolithically connected to at least one of the first and second tubular bodies.

Abstract: A differential force sensor method and apparatus for automatically monitoring manual injections through an intravenous line. The differential force sensor includes two piezoresistive sense die that are packaged in close proximity utilizing a number of packaging processes. The two piezoresistive sense die can be utilized to measure forces exerted on a diaphragm on either side of an orifice. The piezoresistive sense die can be packaged in close proximity to make intimate contact with the diaphragms on either side of the orifice. The differential force sensor further includes two plungers that make intimate contact with the diaphragm and transfer the force into the piezo-resistive sense dies. Additionally, one or more ASICs and microcontrollers can be utilized to provide thermal calibration and differential calculation.