Abstract: An apparatus includes a housing, a flow control mechanism, and an actuator. At least a portion of the flow control mechanism is movably disposed within the housing. The apparatus further includes an inlet port and an outlet port, and defines a fluid reservoir. The outlet port is fluidically coupled to a second fluid reservoir and is fluidically isolated from the first fluid reservoir. The actuator is configured to move the flow control mechanism between a first configuration, in which the inlet port is placed in fluid communication with the fluid reservoir such that the fluid reservoir receives a first flow of bodily-fluid, and a second configuration, in which the inlet port is placed in fluid communication with the outlet port.

Abstract: A connector of the present invention includes a housing and a valve, wherein the housing has a flow path and a pipe connecting port, and the valve is formed of an elastic material and is adapted to block the pipe connecting port. The valve has a substantially columnar deformable portion. The deformable portion has a top surface exposed from the pipe connecting port, a bottom surface opposite to the top surface, and a slit that extends from the top surface to the bottom surface. When the top surface is pressed by the pipe, the deformable portion of the valve will be displaced toward the flow path while elastically deforming, so that inner surfaces that define the slit will face the flow path, and the top surface will form an opening that communicates with the flow path.

Abstract: A drug delivery device for co-delivery of two medicaments. The drug delivery device has a dose setter, a first dose dial component, a second dose dial component, and a collar. The first dose dial component is configured to select a first dose of a first medicament, and the first dose dial component is operably connected to the dose setter. The second dose dial component is configured to select a second dose of a second medicament. In addition, the first dose dial component and the second dose dial component are connected to the collar. The collar is configured to be moved in a proximal direction by actuation of the dose setter. Further, when the collar is moved in a proximal direction, the first dose dial component and the second dose dial component are configured to move proximally to set a dose “A” for the first medicament with the first dose dial component and set a dose “B” for the second medicament with the second dose dial component.

Abstract: A valve for controlling material flow through a catheter, comprises a first flexible member including a first moveable element, wherein, when the first moveable element is in the open position, material may flow past the first flexible member through a first lumen of the catheter and, when the first moveable element is in the closed position, flow through the first lumen is prevented and a first biasing member coupled to the first flexible member for biasing the first moveable member toward the closed position.

Abstract: A drive sleeve is arranged within a body and coupled with a dose member by means of threads. Stop means inhibit a shift of the drive sleeve while allowing a rotation of the drive sleeve. A clutch is provided to lock the dose member rotationally to the body in a releasable manner when a force is exerted on the dose member in the distal direction, the clutch permitting a movement of the dose member in the distal direction with respect to the body.

Abstract: A medicament injection apparatus that permits injection of a fluid medicament into a patient through a needle. The medicament injection apparatus includes a timer and a display, the timer being actuated upon commencement of an injection operation, in which the timer runs to a predetermined time until completion of the injection operation and the display is operated while the timer runs. Thus, informing a user of when a required period for dispersal of an injected medicament has lapsed so that the user knows when to withdraw a needle from the body after the injection.

Abstract: Inline liquid drug medical device having a longitudinal device axis, a housing with a flow control member rotatable within a transverse bore from a first flow control position for establishing flow communication between a first pair of ports for liquid drug reconstitution purposes to a second flow control position for establishing flow communication between a second pair of ports for liquid drug administration purposes, and a manually operated actuator for rotating the flow control member from its first flow control position to its second flow control position.

Abstract: The present invention provides a device and a system for the delivery of biological material across the biological tissue. The device may be for the programmed delivery of biological material through a needle or a micro-needle or micro-needles or biodegradable micro-needles.

Abstract: A method and system is disclosed for operating a medical device with or without a cassette in place. A method is disclosed for adding additional VTBI to an ongoing infusion without stopping the infusion and with maintaining the infusion parameters. A method and system is disclosed for changing the CCA without having to interrupt or completely stop an ongoing infusion. Quick titration buttons are provided to allow improved navigation between various delivery display screens.

Abstract: An enteral feeding system reduces medical risk for aspirational pneumonia when an angle of the head gatch section is outside a predetermined range of 30-45 degrees. The system comprises a hospital bed having a head gatch section and an intravenous pole connected to an enteral feeding pump. The pump has a fluid sensor which operates properly when the pump is positioned along a vertical axis. The pole is connected to the head gatch section at a 30 degree angle offset from a vertical axis. In operation, when the head gatch section is positioned less than 30 degrees, the pump will stop operating and when the head gatch section is positioned at 30 degres, the pump will operate since the pump is positioned along a vertical axis to allow the fluid sensor to detect fluid.

Abstract: A protective sleeve placed within the cylinder of a syringe, the sleeve protects a piston and a computer controlled device or human operator pushing the piston from material leaking past a piston assembly. The sleeve has lips or ridges at either end, one that is attached to the piston assembly at the output end of the syringe and a second lip that is attached with a retention plate at the far end of the syringe. The sleeve may have a bellows or accordion configuration that slides along the inner surface of the syringe cylinder without appreciably loading the drive mechanism.

Abstract: A system and method for a patch-like, self-contained substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir, wherein the device can be attached to a skin surface via an adhesive contact surface and a push button activation assembly can then be used to remove an interlock, allowing a disk, or Belleville spring assembly to apply an essentially even and constant pressure to the contents of the fluid reservoir, allow the release of the patient needles into the skin surface, and establish a fluid communication path between the patient needles and the pressurized fluid reservoir contents. The push button activation assembly further allows the release of one or more improved safety mechanisms after use.

Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.

Abstract: An antibiotic delivery system including an intramedullary stem that is adapted to be removably mounted into a medullary canal of a bone. The stem includes a body having an inlet adapted to be in fluid communication with a source of liquid-borne antibiotic and a plurality of outlets disposed along the stem. A channel extends between the inlet and the plurality of outlets for delivering a fluid-borne antibiotic from the inlet to the plurality of outlets so as to distribute the antibiotic along the medullary canal in a controlled fashion. A method of treating an infected joint during a two-stage re-implantation of an orthopedic implant is also disclosed.

Abstract: A method of placing a catheter into a patient while preventing disadvantageous escape of fluid from the patient comprises providing a catheter secured to a valve hosing. The catheter has a proximal end, a distal end and an interior lumen. The valve housing has a first port, a second port, and a fluid path running between the first and second ports. The catheter and the valve housing have a hollow needle extending therethrough. The method further comprises piercing the patient's skin, thereby inserting the catheter into the patient. The method further comprises holding the catheter and valve housing in place while removing the hollow needle through the catheter and valve housing. The hollow needle passes through the first and second ports of the valve housing.

Abstract: A surgical apparatus includes a hub, a closure valve, an internal seal member, and a spring. The hub defines an internal chamber. The closure valve is disposed within the internal chamber and defines an internal bore extending therethrough. The closure valve is movable relative to the hub between a first position, substantially sealing the internal chamber, and a second position, establishing a fluid passage extending completely through the hub. The internal seal member is disposed within the internal bore of the closure valve and is movable relative to the closure valve between a closed position, substantially sealing the internal bore, and an open position, establishing an internal passage, different from the fluid passage, extending completely through the closure valve. The spring is disposed within the internal chamber and is configured to bias the internal seal member towards the closed position, thereby biasing the closure valve towards the first position.

Abstract: A hub assembly is provided for accommodating a medical professional to grip and manipulate two components of a catheter hub and move one component longitudinally relative to the other, then removably engaging the two components of the catheter hub to restrict movement there between. The two catheter hub components include a proximal hub and a distal hub. The proximal hub and the distal hub are configured to removably engage with one another. The proximal hub is affixed to a first catheter member, such as a multi-lumen catheter, while the distal hub is affixed to a second catheter member, such as a sheath. The first catheter member and the second catheter member are cooperatively engaged and concentric with one another. Relative movement of the proximal and distal hubs translates into relative movement of the first and second catheter members.

Abstract: A device for administering a product dose, the device including a display drum for displaying the product dose, a housing, a first conveying member moveable relative to the housing in a conveying direction, a second conveying member moveable relative to the housing in and counter to the conveying direction, the second conveying member in a first threaded engagement with the first conveying member while being rotationally movable relative to the housing and the first conveying member and being translationally movable relative to the first conveying member counter to the conveying direction, a metering apparatus by which the product dose can be adjusted and which encompasses the display drum, the display drum being rotationally movable relative to the housing while being translationally movable in and counter to the conveying direction in a second threaded engagement, and a coupling element which interconnects the first conveying member and the display drum in a torsion-resistant manner in a coupling engagement

Abstract: Systems and methods for the delivery and monitoring of a medication, such as insulin, to a recipient are provided. An exemplary feature-rich system comprises an infusion pump with a control system for controlling medication delivery by the infusion pump and a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump. Estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile. In other embodiments, the control system comprises a suspend function for temporarily suspending medication delivery by the infusion pump, an alarm profile function for programming a variable alarm volume of the alarm and a simplified menu for controlling the dual wave bolus delivery function.

Abstract: A needleless valve system includes a cannula comprising a cannula tip; a valve comprising a valve tip, wherein the valve is disposed around the cannula; and a housing comprising a housing tip, wherein the cannula tip, the valve tip, and the housing tip comprise a flat surface when the needleless valve system is in a sealed position.

Abstract: The present disclosure relates to an infusion control valve adapted to be actuated by a valve actuator. The present disclosure further relates to an infusion valve actuator adapted to actuate an infusion control valve upon being triggered by an authentication unit. Furthermore, the present disclosure relates to methods for the administration of a substance.

Abstract: A peripheral catheter having a catheter tip diffuser for reducing an exit velocity of an infusant within the catheter. Pluralities of diffusion side holes are provided on the tip portion of the catheter. Some examples further include pluralities of annularly arranged, staggered diffusion holes provided on the tip portion of an intravenous catheter to streamline infusant issued from the diffusion holes. An inner surface of each diffusion hole is further angled relative to the inner surface of the catheter lumen such that an infusant within the lumen exits the catheter though the diffusion holes at an angle less than 90°.

Abstract: A piston for a needleless valve system comprising a head portion configured to be disposed in the needleless valve system and controlling fluid flow through the needleless valve system. The head portion comprising a continuous top surface, and an opening disposed proximate the continuous top surface, wherein the continuous top surface is non-planar when the opening is in an open position.

Abstract: The illustrative embodiments described herein are directed to apparatuses, systems, and methods for managing liquid flow associated with a tissue site that involves using reduced pressure to control fluid flow. In one instance, an apparatus includes a first valve and a second valve in fluid communication with a reduced-pressure source. The valves are movable between an open position and a closed position and are operable to change flow status (open to closed or vice versa) based on a presence of reduced pressure. At least one of the first valve or the second valve is in the closed position to obstruct a flow of a liquid while the other is in the open position. The apparatus also includes a reservoir fluidly coupled to the first valve and the second valve. Other systems, methods, and apparatuses are presented.

Abstract: A valve assembly for use with a catheter assembly is provided. The valve assembly includes a valve housing defining a longitudinal axis and adapted for fluid engagement with a catheter assembly. The valve housing has an internal passageway for flow of fluids relative to the catheter assembly. A valve member is at least partially disposed within the valve housing and defines a valve passage. The valve member is adapted for movement within the valve housing between an open position wherein the valve passage is in general alignment with the internal passageway of the valve housing to permit flow of fluids through the valve housing, and a closed position to substantially occlude the internal passageway of the valve housing. An actuation mechanism is selectively movable in a general longitudinal direction to cause corresponding movement of the valve member between the open position and the closed position.

Abstract: An assembly is disclosed comprising: a reservoir holder, a dose setting mechanism, and flexible fastener configured to fasten the reservoir holder to the dose setting mechanism, wherein the flexible fastener is provided at one of the reservoir holder and the dose setting mechanism. The flexible fastener is configured to releasably fasten the reservoir holder and the dose setting mechanism to each other. Moreover, said flexible fastener is arranged on a retention ring provided at the one of the reservoir holder and the dose setting mechanism. Furthermore, a drug delivery device with such an assembly is disclosed.

Abstract: An IV flow rate regulator for precision dosage of medical liquids including a first part, a second part with an integrated outlet tubular connector and a mating attachment part with an integrated inlet tubular connector, coupled to one another in a rotatable manner with a first elastic gasket in a depression in the base wall of the second part, a second elastic gasket in a depression in the base wall of the mating attachment part, a dosing passage groove provided between the first and second gaskets, the dosing groove opening progressively the communication between the inlet tubular connector and the outlet tubular connector by rotation of the first and second parts. Also provided is a method for the fabrication of the said IV flow regulator.

Abstract: A pressure compensating device includes a compensating disc located within an internal chamber of a housing. The compensating disc has a diaphragm over which fluid passes after entering the internal chamber. The diaphragm deflects in response to a pressure differential between fluid entering the internal chamber and fluid exiting the internal chamber to maintain the set flow rate of the fluid.

Abstract: The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.

Abstract: A medical product configured for use in a medical system and a method of handling a medical system comprising a first subsystem and a second subsystem containing a medical fluid are provided. A connector connects the first and second subsystems for transport of the medical fluid from one of the subsystems to the other subsystem. The connector comprises a valve device, a first connection pipe connectable to the first subsystem, and a second connection pipe connectable to the second subsystem. The valve device comprises a first part and a second part, which are movable in relation to each other to permit an opening movement from a closed position, preventing a fluid communication between the first and second connection pipes, and an open position permitting the fluid communication. The medical product comprises a blocking member preventing, in a blocking state, the opening movement, and permitting changing of the blocking state to a non-blocking state permitting the opening movement.

Abstract: A flushable catheter assembly having features to enable selective activation of fluid flow through the catheter assembly is disclosed herein. A septum is placed within the catheter adapter of the catheter assembly and includes a pathway that is closed prior to being biased open via a septum activator also positioned within the catheter adapter. A plurality of air vent channels is interposed between the septum and the inner surface of the catheter adapter to permit “flashback” of blood during insertion of the catheter into a patient. The septum activator is advanced through the pathway of the septum as a coupler is attached to a proximal opening of the catheter adapter.

Abstract: A valved connector configured to control the leakage of bodily fluid from within a patient. The valved connector including a seal positioned within a lumen of the body of the valved connector. The distal end of the valved connector is adapted to permit access to, or coupling of an apparatus. A proximal end is adapted to be threadably coupled to a secondary device. The needless connector valve being configured to be openable by a dilator or post of an apparatus which is connected to the proximal end of the needleless connector. In the event that a luer coupler or other secondary apparatus is not available, a needle, cannula, trocar, or other instrument can be threaded through the main lumen of the valved connector opening the valve and allowing the passage of fluid directly through the needle, trocar, cannula, or other instrument.

Abstract: An irrigation catheter device, in particular an ablation catheter, including a catheter body in which a central lumen extends from a proximal region into a distal region, wherein a large number of irrigation channels extend away from the lumen, the outlet openings of which out of the catheter body are distributed across the distal end region thereof, wherein sensors are assigned to the central lumen and/or the individual irrigation channels for pressure measurement and/or to measure the flow velocity, to which evaluation means are connected, which are designed to determine the open or closed state of a portion of the irrigation channels on the basis of measured values registered by the sensors.

Abstract: Connector assemblies are provided for controlling flow in a fluid line that include an outer shell, an inner housing, and a tubular member. The inner housing is disposed within the outer shell and includes a boss disposed adjacent a first end of the outer shell. The inner housing is movable axially within the outer shell between first and second positions when a device is connected to the first end. The tubular member is carried by the inner housing and includes a fluid passage extending between a second end of the outer shell. The tubular member moves axially as the inner housing moves between the first and second positions, and cam features on the outer shell and the tubular member cause the tubular member to rotate as the inner housing moves between the first and second positions, thereby opening a fluid path between the fluid passage and the first end.

Abstract: An apparatus comprises a tubular body having a lumen and a distal region, a plurality of ports at the distal region of the tubular body, and a plurality of independently gatable microvalves disposed at the plurality of ports. A port extends from internal to the lumen to outside the tubular body, and a gatable microvalve is controllable by a stimulus to provide and prevent fluidic transfer through the ports.

Abstract: A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10?, 10?, 10?') is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).

Abstract: A medical introducer apparatus for use in inserting an interventional device into a body vessel of a patient. The apparatus includes a housing having a proximal opening, a distal opening, and a chamber positioned between the proximal and distal openings. A sheath, defining a conduit for the interventional device, extends distally from the housing distal opening. A hemostatic valve system is provided in the housing chamber. The valve system includes a plurality of generally elastomeric valve members axially arranged in the chamber. The valve members each have a generally circular hole extending therethrough, which hole is sized for substantially leak-free passage of the interventional device. The valve members are aligned in the chamber to be sequentially penetrable by the interventional device, such that the hole in one valve member is covered by an adjoining valve member.

Abstract: Disclosed herein are methods and devices for processing a biomaterial in a closed system and administering the processed biomaterial to a subject.

Abstract: An improved method of controlling intraocular pressure with a microsurgical system using measured flow rate.

Abstract: In various embodiments, multiple pumps may be used to deliver substances to multiple respective animals. A computer system may send/receive information to/from the pumps (e.g., to control and monitor various aspects of the pumps and/or store information associated with the pump). In some embodiments, the computer system may determine respective controlled delivery rates for the pumps (e.g., based in part on a weight of an animal receiving the substance from the respective pump) and send the determined controlled delivery rates to the respective pumps. The computer system may also receive user identifications from operators controlling a pump (e.g., in response to a pump alarm) and documentation indicators entered by the operator and/or pump to use in documenting pump activity.

Abstract: An anti-free-flow mechanism includes an occluder mechanism which is disposed along a segment of tubing. The occluder mechanism is normally in a biased closed position, but may be moved into an open position by moving an engagement member into engagement with the tubing segment to deform the tubing segment and open a flow channel. Unless force is applied to keep the engagement member in contact with the tubing segment, the tubing will return to the first, closed position.

Abstract: Valves for regulating fluid flows through medical devices are provided. In some embodiments, the valves are adapted for use in high flow applications and multiple valve elements disposed across a plurality of fluid flow paths branching from and into one or more inlets and outlets.

Abstract: A catheter including one or more bidirectional valves is provided. The catheter includes a tubular body having proximal and distal ends, and inner and outer surfaces, and at least one valve formed near the distal end of the tubular body. The valve includes a deformation portion that defines a slit that is openable and closable. The openable/closable slit communicates from the inner surface to the outer surface of the tubular body, wherein the distance between the inner surface and the outer surface of the tubular body progressively becomes thinner approaching the openable/closable slit within the deformation portion.

Abstract: A clamp guard for securing to flexible tubing such as catheters and their extension tubes and about a clamp therealong for housing the clamp at least when the clamp is in a tubing-clamping state, to prevent inadvertent contact of the clamp by a foreign body and undesirable unclamping of the clamp. The clamp guard is removable from around the clamp when desired.

Abstract: Connector assemblies are provided for controlling flow in a fluid line that include an outer shell, an inner housing, and a tubular member. The inner housing is disposed within the outer shell and includes a boss disposed adjacent a first end of the outer shell. The inner housing is movable axially within the outer shell between first and second positions when a device is connected to the first end. The tubular member is carried by the inner housing and includes a fluid passage extending between a second end of the outer shell. The tubular member moves axially as the inner housing moves between the first and second positions, and cam features on the outer shell and the tubular member cause the tubular member to rotate as the inner housing moves between first and second positions, thereby opening a fluid path between the fluid passage and the first end.

Abstract: A catheter includes an elongated tubular body including a first wall and second wall defining first and second lumens, respectively. Each wall extends to a distal end and defines a distal opening. The first and second walls may each include one or more side openings disposed proximal of the distal end. The first and second lumens are separated by a septum. The septum includes a septum extension extending distally from the septum. The septum extension is adapted to articulate relative to the septum in response to fluid flow into and out of the distal openings of the first and second lumens. The septum extension is dimensioned to partially obstruct fluid flow into the catheter through one of the distal openings upon the articulation of the septum extension.

Abstract: A slide clamp for use with an infusion pump and infusion set provides finger grips and support members for supporting the infusion tubing. The finger grips make the slide clamp easier to use while reducing the risk of error. The tubing support members reduce the likelihood of improperly loading the tubing and reduce the risk of kinking the tubing during use. An infusion set is provided wherein the slide clamp may be coded through the use of colors, holes, or the like so as to identify the type of infusion tubing used therewith. The infusion pump can identify the code on the slide clamp and thereby determine the type of infusion tubing, and thereby allow access only to infusion programs for drugs or infusion solutions which are compatible with the particular type of infusion tubing.

Abstract: In renal haemodialysis there is a condition whereby the patient can by at serious risk of harm if the venous line becomes disconnected or the venous needle becomes dislodged and the haemodialysis machine does not detect this condition. The invented device is designed to safeguard haemodialysis patients from serious losses of blood through venous line disconnection or venous needle dislodgement. The invented device is designed to clamp the venous line automatically before venous needle dislodgement or venous line disconnection becomes a serious problem and to make the haemodialysis machine stop drawing blood from the patient This will cause the haemodialysis machine to alarm in the normal way so as to alert the patient or healthcare worker to the problem. The invented device will have to be manually reset before therapy can continue.

Abstract: A flushable catheter assembly having features to enable selective activation of fluid flow through the catheter assembly is disclosed herein. A septum is placed within the catheter adapter of the catheter assembly and includes a pathway that is closed prior to being biased open via a septum activator also positioned within the catheter adapter. A plurality of air vent channels is interposed between the septum and the inner surface of the catheter adapter to permit “flashback” of blood during insertion of the catheter into a patient. The septum activator is advanced through the pathway of the septum as a coupler is attached to a proximal opening of the catheter adapter.

Abstract: A skin seal or trocar stabilizer with an inflatable membrane disposed inside, whereby medical instruments may be passed through the skin seal into a endoscopic work space while the inflatable membrane is inflated, thereby allowing the use of normal short conventional open surgery instruments during endoscopic procedures and during insufflation.