Abstract: For application of active substances to a wound surface a porous padding (12) is provided upon the wound (10), which is sealingly covered over with a foil (14). A fluid active substance is introduced into the padding (12) via a supply line (22) and is then suctioned out of the padding (12) via a removal line (26). Closure mechanisms (32, 34) control the introduction of the active substance and the suctioning off of the active substance in the manner, that the active substance after being introduced remains for a predetermined dwell time in the padding (12), before it is suctioned off. After the suctioning off the vacuum in the padding (12) is maintained for a certain time period, before renewed introduction of the active substance. The opening of the closure mechanisms (32, 34) are temporally controlled to occur slowly.

Abstract: A method for stimulating new tissue growth is provided in which a limb is introduced into an interior portion of an outer cover. A porous component is applied to at least a portion of the limb within the outer cover. An opening through which the limb was introduced is sealed, and a negative pressure is applied to the interior portion to stimulate new tissue growth.

Abstract: An apparatus and method of use are disclosed for rapidly and repeatedly cleaning a skin area during tattooing or body piercing. The apparatus includes a plurality of serially dispensable, antiseptic wet wipes pre-moistened with “tincture of green soap” solution. It eliminates any need to dilute a concentrated green soap solution or clean a spray bottle, and allows a tattoo artist to quickly and conveniently obtain and use a wet wipe of the invention in a controlled and consistent manner using only one hand, thereby avoiding interruption of the procedure and contamination of the wet wipe. The wet wipes and/or green soap can be medically approved, and the wipes can be disposable and/or made from non-woven paper, with a preferable size of 19.5 by 17.0 centimeters. The wet wipes can be interleaved or formed in a continuous sheet with perforated separations, and can be folded, or configured in a roll.

Abstract: Elastomeric film-like products such as natural latex gloves are coated with novel lubricity compositions and compositions which protect the skin of the wearer from certain undesirable medical conditions. In powder-coated gloves, the coating composition comprises rice starch, and optionally USP-grade colloidal oatmeal in pharmaceutically accepted concentration. In powder-free gloves, the coating composition comprises colloidal oatmeal enhanced water or beta glucan solution, optionally in combination with one or more other starch components. Colloidal oatmeal enhanced water, and methods of making the colloidal oatmeal enhanced water are also disclosed. In addition, beta glucan solution, and methods of making the beta glucan solution are also disclosed. A liquid referred to herein as Polycoat may also be made by mixing colloidal oatmeal enhanced water with beta glucan solution, and the resulting liquid may be applied to elastomeric articles such as gloves.

Abstract: A portable closed wound drainage system that uses a pouch shaped dressing which is inserted into a wound. At least a portion of the outer surface of the pouch is porous to allow exudates to enter. Exudates are removed from the pouch by flexible tubing which is secured inside the pouch at one end and secured at the other end to a portable drain/suction unit. The pouch contains porous material. The tubing can have a single or multi-lumen structure. The pouch and the tube are sealed by a flexible sealing material which is applied to the outer surface of the skin. A cosmetic cover sheet is attached to the patient's skin over the closed wound drainage system.

Abstract: The present invention concerns a device for metering products intended to be applied to the skin, in particular pharmaceutical or cosmetic compositions. The invention relates more particularly to a device taking the form of an applicator stick, the graduations of which allow users to determine precisely the quantity of medication to be applied to the skin as a function of the surface area to be treated.

Abstract: A method of delivering a drug or other compound to the lens of the eye. A conduit through which a drug is introduced penetrates at least the outer lens capsule for drug delivery. When withdrawn, the aperture is self-sealing, thus minimizing trauma and minimizing the risk of cataract formation. The drug remains localized within the lens.

Abstract: A disinfectant delivery system and method of providing alcohol-free disinfection to a body to be disinfected, as well as a method of infection reduction by preparation of a patient before an invasive procedure. A blended cloth comprising first fibers and second fibers is provided with the first fibers generally being greater in quantity by weight than the second fibers. A disinfectant solution impregnates the blended cloth, with the disinfectant solution having chlorhexidine gluconate as an active ingredient and having no alcohol. In the method according to the invention, at least one impregnated blended cloth is used to disinfect at least a portion of a body. A plurality of blended cloths can be provided for disinfecting discrete portions of the body.

Abstract: Dry powders containing bioresorbable hyaluraonic acid (“HA”) are applied directly to a desired location in a patient wound to reduce adhesions, without first forming a hydrated gel. HA includes hyaluronic acid that has been modified, cross-linked or combined with other substances. it is important to control the size of the particles in the powder. The powder is essentially dry and blowable powder. At least 90% of powder particles have a maximum dimension between 30 ?m and 1 mm.

Abstract: A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.

Abstract: A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.

Abstract: A therapeutic article includes a skin contact layer having a plurality of fibers forming a plurality of point-bearing surfaces configured for wear against a user's skin; a personal care composition disposed proximate the fibers; an external layer attached to the skin contact layer; and an intermediate layer interposed between the skin contact layer and the external layer, the intermediate layer being configured to activate the personal care composition, the external layer being configured to direct the activated personal care composition through the skin contact layer to treat the user.

Abstract: Disclosed are devices and methods for the transfer of fluids and potentially toxic chemicals into the lens capsule by creating a closed system preventing the fluids from entering the anterior chamber of the eye and thus causing damage to other ocular structures. The invention comprises one or more fluid conduits which communicate with a plug which maybe inserted through the corneal incision and placed onto the anterior surface of the capsule around the capsulorhexis. The plug is adapted to seal against the anterior surface of the lens capsule. In preferred embodiments, the flow of fluids into and out of the plug (and therefore the capsule) are controlled from a separate fluid flow controller.

Abstract: The present invention relates to a method of treating a wound and an apparatus for promoting wound healing. An enclosure is applied over the site of a wound and filled with a physiologically acceptable rinse solution. The physiologically acceptable rinse solution treats the wound and can promote the growth of tissue cells in the wound. Following exposure to the wound, the physiologically acceptable rinse solution is analyzed by a data sensor to determine the wound bed biology.

Abstract: The invention teaches devices and methods for chemically tanning human skin. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).

Abstract: A control unit is adapted for use with a vacuum wound bandage. The control unit has a canister to collect waste material from the vacuum wound bandage, a fluid source to irrigate the wound, and a door to at least partially cover the fluid source.

Abstract: An instrument and technique for the removal of epidermal layers in a controlled manner utilizing a hand-held instrument with a working end that (i) a vacuum aspiration system, (ii) a source for delivery of a sterile fluids or pharmacological agents to the skin; and (iii) a skin interface surface in the working end that has specially shape structure for abrading surface layers of the patient's epidermis as the working end is moved over the patient's skin while at the same time causing rapid penetration of the fluids into the skin for therapeutic purposes. Movement of the working end across the skin causes abrasion of the surface layers in a path over the patient's skin. The method of the invention may be used in a periodic treatment for the removal of superficial skin layers that enhances the synthesis of dermal collagen aggregates by inducing the body's natural wound healing response.

Abstract: The use of elastomeric gloves, slippers, finger and toe covers for the cleaning, debriding and application of medicines by utilizing the repeated self-contained flushing and pumping caused by normal appendage motion and elastomeric distortion and equalization either alone or in tandem with the auxiliary agitation from an external ultrasonic source if necessary.

Abstract: The subject invention provides novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation. In one embodiment the subject invention provides a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

Abstract: A patient gown comprised of therapeutic fabric for the prevention and treatment of skin wounds, and pressure wounds in particular, which includes a woven fabric having warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns is at least about 40% by weight of the fabric of continuous filament nylon, and the other of the warp or filling yarns is from about 0% to about 60% by weight of the fabric of continuous filament polyester or nylon having non-round filament cross sections. The fabric includes a conductive yarn at about 1% to about 2% by weight to control static dissipation, and an antimicrobial substance is topically applied or inherently available in the fabric. A method of using the patient gown to prevent and treat skin wounds, and pressure wounds in particular, is also disclosed.

Abstract: The subject invention provides novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation. In one embodiment the subject invention provides a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

Abstract: A diffusing device for treating tissue has multiple cells arranged in a cell layer, the cells filled with or charged with a therapeutic agent, an occlusive layer in direct communication with the cell layer, and a diffusion layer in direct communication with the cell layer. In use the diffusing device is sealed peripherally about an area of tissue and therapeutic agent is released from the cells through the diffusion layer based on the diffusion properties of the diffusion layer.

Abstract: The present invention provides a treatment apparatus. The apparatus contains a reservoir or generator for a treatment solution, a mechanism for delivering the treatment solution to a wound site, and a mechanism for applying the solution to a wound, tissue, bone or surgical cavity for treatment. The apparatus may apply the solution (e.g., a solution containing hypohalous acid) with, for example, an occlusive wound dressing, pulsative lavage device, hydrotherapy, hydrosurgical device, and/or ultrasound. A waste container may be operably connected to the apparatus for collecting waste from the wound by run-off, or by applying negative pressure (e.g. a vacuum). Because the apparatus of the invention can optionally be portable or mobile, the invention is suitable for use in hospitals and nursing homes, as well as for home wound care.

Abstract: A system and method for generating an oxygen enriched aqueous solution for therapeutic application includes a diffuser comprising a first diffusing member having a surface incorporating surface disturbances, and a second diffusing member positioned relative to the first diffusing member to form a channel through which an aqueous solution and oxygen gas may flow. A reservoir containing the aqueous solution is connected to a pump that draws the aqueous solution from the reservoir and inputs the aqueous solution into the diffuser. The aqueous solution is moved through the channel relative to the surface disturbances to create cavitation in the aqueous solution to diffuse the oxygen gas into the aqueous solution to produce an oxygen enriched aqueous solution.

Abstract: The invention provides a device for a percutaneous absorption preparation, provided with a solution storage container which can exhibit good solution migration independently of the level of force. The device for a percutaneous absorption preparation comprises an electrode film comprising a base member (1) and an electrode layer (2) and having a dissolution liquid passage hole (9), a drug impregnation member (3) mounted on the electrode layer (2) side of the electrode film, and a dissolution liquid storage container (5) bonded to the base member (1) side of the electrode film via a lid member (7) covering the solution passage hole (9). The dissolution liquid storage container (5) comprises a bottom and a sidewall. A protrusion (5b) which faces the dissolution liquid passage hole (9) is provided at the center of the bottom, and the sidewall is provided with a vertically folded part (5c).

Abstract: A medical laser gel applicator apparatus for applying surgical gel for craniofacial surgery includes a gel tube having an application tip from which gel is applied to a patient, and a bottom slidably movable within said tube pushing gel out through said application tip, a gun having a handle, a chamber into which said gel tube inserts, a plunger with a shaft and a plunger face in which said plunger face contacts said removable bottom, a trigger in electromechanical communication with said plunger wherein when said trigger is depressed the plunger pushes against said bottom sliding said bottom in said tube, pressuring said gel out of said application tip, and wherein when said trigger is released, said plunger backs off of said bottom, stopping the flow of said gel.

Abstract: A non-invasive therapeutic device includes a housing comprising a cavity and a bottom surface. A plurality of light emitting arrays are positioned within the bottom surface. At least one fan positioned within the cavity to provide at least cooling to the patient. The device includes a controller positioned on the housing for controlling the plurality of light emitting arrays and the at least one fan such that a phototherapy treatment can be applied to a selected region of a patient.

Abstract: A wash cylinder or chamber for an automated cleaning station to clean an object or a person's body part includes nozzles on the interior of the cylinder, the nozzles of one embodiment comprising an increasing roll angle providing a novel spray pattern. Additionally, embodiments of the invention include fluid guidance and conveyance structures, angled nozzles, sealing structures, finger guards, nozzle ribs, wash chamber seating mechanisms and drains, and nozzle inlays having a plurality of nozzles. Also disclosed are methods of washing an object or body part using a wash cylinder or chamber and methods of assembling a wash cylinder or chamber.

Abstract: A system and method for collection of fluids, as may be used in evaluation of drag dose delivery completeness after parenteral injection by measuring fluid volume leakage from the injection site is provided. The system and method optionally separate the collection and measurement steps, which make the system and method easy to use in multi-site clinical trials, and for batch weighing operations.

Abstract: A subpalpebral lavage catheter device for a mammal comprising a subpalpebral catheter having a first and a second end wherein the first end is located under the skin of the mammal and the second end further comprises an injection port, a hollow pouch, wherein the pouch has an opening adapted to receive the injection port of the catheter, a means for closing the opening of said pouch, and a plurality of loops attached to a side of the pouch, spaced apart and of a length wherein the loops are adapted to be braided into hair of the mammal.

Abstract: A wash cylinder or chamber for an automated cleaning station to clean an object or a person's body part includes nozzles on the interior of the cylinder, the nozzles of one embodiment comprising an increasing roll angle providing a novel spray pattern. Additionally, embodiments of the invention include fluid guidance and conveyance structures, angled nozzles, sealing structures, finger guards, nozzle ribs, wash chamber seating mechanisms and drains, and nozzle inlays having a plurality of nozzles. Also disclosed are methods of washing an object or body part using a wash cylinder or chamber and methods of assembling a wash cylinder or chamber.

Abstract: A sheet assembly comprises an insoluble layer disposed to define an inner reservoir and a medicament disposed in the inner reservoir. A garment is formed from said textile assembly.

Abstract: A dermal, transdermal, mucosal or transmucosal delivery device includes a backing layer overlying an ingredient containing reservoir, and having a microprotrusion array attached thereto, a cover for the reservoir having at least one opening therethrough, an adhesive layer and a liner layer. Upon removal of the liner layer, the device may be placed over the desired area of the skin or mucosa and adhesively applied thereto allowing the ingredients to flow from the reservoir through the at least one opening to the skin or mucosa.

Abstract: A wound treatment device for treating damaged body tissue comprising an encapsulating member having a size and shape capable of being attached to a patient to encapsulate a wound. A fluid communication member is provided for introducing treatment fluid within the encapsulating means for treatment of the wound. The fluid communication member is connected with a supply means for supplying treatment fluid thereto. The fluid communication member is capable of simultaneously transmitting multiple treatment fluids from the supply means into said encapsulating member. The inner surface of the wall of the encapsulating member is textured to allow fluid flow across the wound. The encapsulating member is also formed from a clear material to permit continuous visual inspection of the wound while maintaining a sterile environment.

Abstract: A device and method for removing facial blemishes, including sebum that blocks facial pores. The device includes a substantially flat, elongated and rigid element having a first surface and a second surface, and a distal end and a proximal end. The device also includes a base member to which the rigid element is attached such that a collection area is formed between the second surface of the distal end of the rigid element and a portion of the base member.

Abstract: A wash cylinder or chamber for an automated cleaning station to clean an object or a person's body part includes nozzles on the interior of the cylinder, the nozzles of one embodiment comprising an increasing roll angle providing a novel spray pattern. Additionally, embodiments of the invention include fluid guidance and conveyance structures, angled nozzles, sealing structures, finger guards, nozzle ribs, wash chamber seating mechanisms and drains, and nozzle inlays having a plurality of nozzles. Also disclosed are methods of washing an object or body part using a wash cylinder or chamber and methods of assembling a wash cylinder or chamber.

Abstract: A wash cylinder or chamber for an automated cleaning station to clean an object or a person's body part includes nozzles on the interior of the cylinder, the nozzles of one embodiment comprising an increasing roll angle providing a novel spray pattern. Additionally, embodiments of the invention include fluid guidance and conveyance structures, angled nozzles, sealing structures, finger guards, nozzle ribs, wash chamber seating mechanisms and drains, and nozzle inlays having a plurality of nozzles. Also disclosed are methods of washing an object or body part using a wash cylinder or chamber and methods of assembling a wash cylinder or chamber.

Abstract: A disposable treatment article or disposable cleaning article that includes a hydrophobic nanoporous material. The disposable treatment or cleaning article is configured to contact and apply the nanoporous material to a surface. The nanoporous material is configured to form hydrophobic nanostructures on a surface upon the application of an activation stimulus. The nanostructures provide an anti-contamination benefit to the surface upon which the nanostructures are disposed.

Abstract: A wound shield including a conformable frame to circumscribe a wound and warm water circulating system to maintain a warm environment. Any suitable dressing may be secured over the conformable frame providing separation between the wound and the dressing. The wound frame may provide pressure relief around a wound or pressure sore to permit healing. A conformable frame may be composed of one or more layers of any suitable material and may include adhesive on one or more surfaces to secure the frame to the wound site and or to secure the dressing to the conformable frame.

Abstract: Provided are methods of, and personal care products for, applying a structured composition to a body with reduced wet slip. The methods and products apply the composition such that upon application a plurality of channels are disposed between the composition and the substrate.

Abstract: A system and method for rejuvenating skin through ablation using a handheld device (200) having a removable treatment component (213) with an abrasive material on one surface of the component which surface is in a portion of the treatment component (213) configured to conform to a skin surface. The system further includes application of other elements to facilitate skin recovery and rejuvenation processes.

Abstract: A topical product including but not limited to a feminine hygiene product or incontinence shield which contains at least two kinds of particulate metals distributed throughout which, when in contact with moisture, form a galvanic current (virtually if not completely imperceptible to the user) that has antimicrobial effect on all pathogens. Galvanic current virtually or completely imperceptible to the user facilitates antimicrobial effect.

Abstract: Motion artifacts less electrode for bio-potential measurements and electrical stimulation is discussed under the present invention. Three different arrangements of the electrode are introduced. Further the electrode embodiments are generalized for reducing motion artifacts of any skin contact senor or an actuator embodiment. In addition a piggy backed daisy chained sensor nodes or actuator nodes cabling system is introduced to minimize the motion artifacts further. A PPG sensor is constructed according to the generalized sensor embodiment and this PPG sensor is used for constructing an ear wearable heart rate monitoring unit. Moreover an ear wearable EEG monitoring system based on piggy backed daisy chained sensor or actuator nodes and caballing arrangement is illustrated.

Abstract: A novel system for coloring the human eye is presented, including methods of coloring the conjunctiva on its internal or external surface, coloring the sclera, coloring the iris, suspending colorant in the subconjunctival space, and combinations of two or more of these methods. The system avoids tattooing, implanting, and corneal modification. Permanent results may be obtained. Colorants may be coverings, suspensions, or stains.

Abstract: The present invention provides pharmaceutical compositions for treating a paediatric mammal, the compositions comprising a therapeutic agent and a pharmaceutically acceptable carrier, the composition being suitable for topical application resulting in transdermal administration of the therapeutic agent and a systemic therapeutic effect. The invention also provides relates uses of the compositions, applicators and kits.

Abstract: The invention provides a suction-cleansing device that is capable of forming a swirling stream at a position close to skin and has both a cleansing and a massaging effect by adequately maintaining a state of minute air bubbles in the stream of water, comprising a vessel body having a hollow portion converging from the rear part side thereof toward the front part side thereof, an air/liquid jetting port secured at the front end portion of the vessel body, a liquid-introducing pipe 4 connected to the circumferential wall at the rear part side of the vessel body in the tangential direction, and an air/liquid jet-guiding portion that is disposed at the outer circumferential portion of the air/liquid jetting port and is widened to open from the air/liquid jetting port toward the jetting direction.

Abstract: The present invention comprises methods and compositions for making a silver-containing antimicrobial hydrophilic material. More particularly, the present invention comprises methods and compositions for stabilized silver antimicrobial devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide, and an active agent. The matrix may be formed into any desired shape for its desired uses.

Abstract: This disclosure describes a high-pressure gas powered full body self misting device that allows a person to spray a mist onto their whole body at once without using electricity, and without having to hold anything in their hand, such as a can or misting spray wand. This device can be used as a simple, do-it-yourself, misting system for fluids that are commonly applied to or around the body including, but not limited to, tanning solution, skin lotions, and aromatherapy mist.

Abstract: A method and apparatus for applying an atomized liquid solution upon a person, comprising a spray enclosure booth; an exhaust vent located below an anticipated user's facial area zone, the exhaust vent disposed within the bottom tray or a lower area of at least one wall or a lower area of a door and configured for exhausting ambient atomized liquid solution from the spray enclosure booth; a rigid conduit support defining a central air flow conduit connected to a bottom tray and pneumatically connected to an exhaust vent and providing structural integrity to the enclosure booth; an atomizing spray head assembly movably connected to the rigid conduit support and physically supported by the rigid conduit support; and an exhaust system configured to exhaust ambient atomized liquid solution from the spray enclosure booth by drawing atomized solution into the exhaust vent then through and out of the rigid conduit.

Abstract: Disclosed is the use of an antagonist of Interleukin 1 receptor type 1 (IL-1R1) for the manufacture of a medicament treating, preventing or suppressing lung inflammation or a respiratory disease. In some embodiments of the described invention, the medicament is for local administration to pulmonary tissue. Also disclosed are methods for treating lung inflammation or a respiratory disease.