Abstract: A disposable medicine delivery unit for use in a needleless hypodermic injector is configured to allow economical replacement, after each injection, of a patient contact surface and the entire injection flow-path of the medicament, to thereby ensure sterility with less need for repeated equipment cleaning and sterilization procedures. The delivery unit includes a piston seal configured to prevent improper reuse. The piston seal deforms and sticks in a conical end of the medicine delivery chamber at the end of its injection stroke. A push-only connection between the piston seal and a piston drive rod of the injector ensures that the latter cannot be used to retract the former. Preferably, the piston seal also includes a protruding nipple which enters and destroys the injection orifice following an injection, to further disable the delivery unit.

Abstract: A needleless injection system and method for injecting a medical product comprises a needleless injection device having a nozzle assembly defining an ampule chamber for holding medication, an energy device for pushing medication out of the nozzle assembly, and an energy device actuating mechanism. These components are operatively contained in a housing configured for a hand held operation. The energy device is a self-contained gas spring operatively connected to a plunger operating within the ampule chamber. The gas spring is preferably stepped which can be used in many different applications, an air gun being one. The injection device can be provide with a coupling device for coupling a medication supply vial to the nozzle assembly. The nozzle assembly is removably situated in the housing with the plunger removable therewith.

Abstract: A jet injector, and a method, for injecting fluid medicament into a patient in a two-stage process. During the first stage fluid is expelled from the injector under relatively high pressure, to create a hole through the skin of the patient. During the second stage, fluid is infused through the hole into the patient at a much lower pressure, and for a much longer period of time. The jet injector includes a syringe unit, and a drive mechanism which is selectively connectable with the syringe unit. Specifically, the drive mechanism includes two springs which are positioned to urge against a push rod as they elongate. When the drive mechanism is engaged with the syringe unit, the push rod is positioned longitudinally co-linear with a plunger in the chamber. When the springs are released, they push the push rod which, in turn, pushes the plunger, causing the fluid to be expelled through an injection tube connected to the chamber.

Abstract: A needleless injector for injecting medication through the skin of a patient includes a vial which holds a volume of liquid medication. The vial includes a vial piston which moves to force the liquid medication out of the vial. A power mechanism applies force to the vial piston. The power mechanism includes a power piston which has a plurality of ratchets. A spring is positioned to apply force to the power piston. A trigger engages the ratchets on the power piston to hold the power piston in place against the force applied by the spring. The trigger selectively releases the power piston so that the power piston moves in response to the force applied by the spring. The power piston applies the force to the vial piston to cause the vial piston to force the liquid medication out of the vial. A cocking mechanism applies force to the power piston to move the power piston against the force of the spring to engage the ratchets.

Abstract: A needleless syringe having a membrane which is ruptured by gas pressure to generate a supersonic gas flow in which particles containing a therapeutic agent are injected.

Abstract: In a needle-less injector combining an actuator and a medicament cartridge, the actuator includes a housing with a forward portion to which the cartridge is connected. An impact member is mounted within the housing inward of the forward portion so as to be movable toward the forward portion, where it may strike components of the cartridge to effect expulsion of a dose of medicament. A chamber is provided within the housing and is pre-filled with a pressurized gas which is in communication with and exerts a constant force on the impact member, tending to urge it towards the forward portion.

Abstract: A needleless injection system and method for injecting a medical product including a needleless injection device having a nozzle assembly defining an ampule chamber for holding medication, an energy device for pushing medication out of the nozzle assembly, and an energy device actuating mechanism is disclosed. These components are operatively contained in a housing configured for hand held operation. The energy device is a self-contained gas spring operatively connected to a plunger operating within the ampule chamber. The gas spring is preferably stepped which can be used in many different applications, an air gun being one. The injection device can be provided with a coupling device for coupling a medication supply vial to the nozzle assembly. The nozzle assembly is removably situated in the housing with the plunger removable therewith.

Abstract: Needleless jet-injection device, characterized in that it consists of a body (1) having at one of its ends (4, 5) a cap (3), which, thanks to a relative movement between these elements, may drive a loading mechanism (2), co-operating with an impact component (17) which has to strike the piston of a cartridge (28) which is made of a material that does not pollute the environment and which contains the active product to be injected, this cartridge (28) being moreover placed at the other end of the said magazine-less body (1) and in the axis of said impact component (17), for single use.

Abstract: A safety mechanism for aiding in the prevention of accidental or unintentional discharge of a needleless injection device having a power unit, a housing, a plunger disposed within the housing, a trigger assembly, and a nozzle. The safety mechanism includes a locking member which is disposed at least partially on the exterior of the housing. The locking member works in concert with the triggering assembly to the prevent movement thereof, thereby preventing activation of the power unit to eject fluids through the nozzle. The locking member also works in concert with an interlocking sleeve which prevents activation of the injector when the nozzle is removed therefrom. The safety mechanism also includes a feature for automatically returning the locking member to a locked position after activation.

Abstract: An improved medication delivery device is a pen sized instrument that is powered by compressed inert gas. The needle-less injector device contains pre-filled and pre-measured medication dosages. The injector device has a pre-filled and self-contained compressed gas for providing pressure to inject the medication into the skin surface without the use of a needle. The injector device has a pressure sensitive deployment mechanism which insures proper seating of the injector face against the skin surface before medication delivery is accomplished. The needle-less injector device assures safe use by inexperienced operators (including children) under adverse conditions.

Abstract: An apparatus and method are disclosed that utilize piezoelectric materials as part of a delivery system capable of the rapidly repetitive dispensing of a fluid to an intended target site. In a particular embodiment, the appartus contemplates a solid state needleless injection system which comprises a first housing structure having a dispensing chamber of variable volume capacity and at least one nozzle element for fluid discharge, and a fluid reservoir operatively connected to the first housing structure, and a second housing structure containing at least one piezoelectric actuator. A valve means is disposed between the fluid reservoir and the dispensing chamber to control the flow of said fluid therebetween. The fluid which may be a medication, is forced out of the dispensing chamber through an injection port upon actuation of the piezoelectric actuator.

Abstract: An ejection apparatus for the high pressure ejection of a liquid. The apparatus has the following elements: (a) a pressure chamber for containing the liquid; (b) an ejection opening communicating between an outside and an inside of the pressure chamber; (c) a working piston displaceable in the pressure chamber from a first position at a beginning of a working stroke to second position at an end of the working stroke, having (1) a first end defining a first volume within the pressure chamber when the working piston is at the first position and displacing a second volume, less than the first volume, when the working piston moves from the first position to the second position, and (2) having a second end distal from the first end; and (d) a drive for driving the working piston including (1) an impact member for elastically impacting the second end of the working piston to cause the working piston from the first to the second position and (2) means for accelerating the impact member to impact the working piston.

Abstract: A nozzle assembly adapted for an injector, includes a guide for proper application of injections. The guide has first and second wings each extending outwardly and away from the chamber at an angle. These wings are preferably symmetrical and form a V-shape to accommodate appendages such as fingers, toes, or penises. The wings may be curved or straight depending upon the curvature of the substrate to be injected. Also, depending upon the angle layout or length of the wings relative to the chamber and the symmetry of the wings, injections can be set to penetrate at almost any desired angle.

Abstract: A plunger/ram assembly adapted for a hypodermic fluid injector having a nozzle body defining a fluid chamber and an orifice communicating with the chamber. The plunger/ram assembly comprises a plunger adapted to be movably positioned in the chamber and a ram assembly. The ram assembly is operatively connected to the plunger for drawing fluid into and expelling fluid out the chamber through the orifice. The ram assembly includes first and second driving members spaced apart by a preselected free travel distance and a resilient biasing member having a preselected preload. The resilient biasing member is operatively disposed for maintaining the free travel distance when the preload is greater than a force applied to the first driving member. The maximum fluid pressure generated by the plunger/ram assembly is controlled by a free travel distance or gap existing between first and second driving members before the injector is fired.

Abstract: A multiple use needle-less hypodermic injection device for individual users comprising of a light weight, pocket sized, spring powered unit, and a multiple use, low cost, easily replaceable thermoplastic injection head. The present invention targets the single-patient-self-injection applications, such as insulin users, when risks of cross contamination between different patients are not present, therefore not requiring the parts containing the medicament dose, or the parts in contact with the delivery of the medicament dose, to be necessarily disposed and replaced after each injection.

Abstract: A needleless, low pressure, air powered medicine injector with a quick disconnect medicine delivery assembly removably connected to the injector housing. Low pressure air drives a biased piston through a discharge stroke, beginning from the retracted position into the medicine chamber, thereby forcing medicine through a one-piece nozzle. A removable chamber filling mechanism connected to the housing is coupled to the medicine chamber through fill ports, such that the medicine chamber is filled utilizing a positive pressure medicine distributor. A movable spacer collar positioned in front of the nozzle provides an air gap between a patient's skin and the one-piece nozzle. A safety interlock coupled to an activating mechanism and the chamber filling mechanism prevents unwanted discharge of the injection.

Abstract: An improved medication delivery device is a pen sized instrument that is powered by compressed inert gas. The needle-less injector device contains pre-filled and pre-measured medication dosages. The injector device has a pre-filled and self-contained compressed gas for providing pressure to inject the medication into the skin surface without the use of a needle. The injector device has a pressure sensitive deployment mechanism which insures proper seating of the injector face against the skin surface before medication delivery is accomplished. The needle-less injector device assures safe use by inexperienced operators (including children) under adverse conditions.

Abstract: A nozzle assembly adapted for a fluid injector having a ram, includes a plunger assembly having first and second driving members. The first and second driving members are apart according to a predetermined first distance. The second driving member is spaced apart from the ram according to a predetermined second distance. The first and second distances are resiliently maintained by a resilient spring member operatively disposed between the two driving members. One of the first and second distances is selected to be the smallest and thereby controls the maximum pressure at which fluid is expelled from the nozzle assembly.

Abstract: A system is provided that is useful for a hypodermic jet injection of medication without piercing the skin with a needle. The system includes a spring actuated needleless hypodermic injector device for injecting medication through the skin. The injector device includes an ampule assembly having a chamber for holding liquid medication and an injector for receiving and mounting the ampule assembly. A plunger assembly, movable within the ampule chamber is used for drawing liquid medication into the ampule chamber and for ejecting liquid medication out from a chamber. The injector includes a spring actuated piston which provides a force to move the ampule assembly plunger and thereby force liquid medication to leave the chamber at such velocity that it can be hypodermically injected at an injection site. The system also includes a coupler for use on a medication vial for transferring medication to the ampule assembly.

Abstract: The present invention relates to a nozzle assembly adapted for use with an injector device having an energy generating source and a chamber adapted for holding a fluid and having first and second end portions with an orifice defined at the first end portion for passage of the fluid and being open at the second end portion. The device includes a first driving member movably positioned in the chamber; a second driving member movably positioned in the chamber and spaced apart from the first driving member according to a predetermined travel distance and including an end portion operative for expelling fluid out of or drawing fluid into the chamber via the orifice; and a spacing member disposed between the first and second driving members for maintaining said predetermined travel distance during displacement of the first and second driving members before the energy generating source is activated.

Abstract: A novel device and method for the application of two or more components of a fibrin sealant using a gas is disclosed. The novel device and method involve the concentric arrangement of annular apertures for each of the components concentric with and radially outward of a center gas discharge aperture in the exit end of a spray head. Reservoirs for each component, for example syringe cartridges or cylinders, are in dextrete fluid communication with the spray head and preferably can be activated by a common means.

Abstract: A needleless injection system and method for injecting a medical product comprises a needleless injection device having a nozzle assembly defining an ampule chamber for holding medication, an energy device for pushing medication out of the nozzle assembly, and an energy device actuating mechanism. These components are operatively contained in a housing configured for a hand held operation. The energy device is a self-contained gas spring operatively connected to a plunger operating within the ampule chamber. The gas spring is preferably stepped which can be used in many different applications, an air gun being one. The injection device can be provide with a coupling device for coupling a medication supply vial to the nozzle assembly. The nozzle assembly is removably situated in the housing with the plunger removable therewith.

Abstract: A hypodermic fluid dispenser and a collapsible body for the hypodermic fluid, with a hypodermic needle injecting the fluid once sufficient pressure is applied to collapse the body. There is also disclosed an electrical hypodermic fluid dispenser having a reusable, rechargeable power source, and a reservoir from which hypodermic fluid can be withdrawn for injection through a single injection orifice.

Abstract: A system is provided that is useful for a hypodermic jet injection of medication without piercing the skin with a needle. The system includes a spring actuated needleless hypodermic injector device for injecting medication through the skin. The injector device includes an ampule assembly having a chamber for holding liquid medication and an injector for receiving and mounting the ampule assembly. A plunger assembly, movable within the ampule chamber is used for drawing liquid medication into the ampule chamber and for ejecting liquid medication out from a chamber. The injector includes a spring actuated piston which provides a force to move the ampule assembly plunger and thereby force liquid medication to leave the chamber at such velocity that it can be hypodermically injected at an injection site. The system also includes a coupler for use on a medication vial for transferring medication to the ampule assembly.

Abstract: This invention relates to a new and improved design associated with the fabrication and construction of a needleless transfer system wherein through the use of a unique valve mechanism there is avoided the necessity to utilize a needle in conjunction with a syringe for purposes of transferring and/or injecting a liquid medium from one environment into another environment. By having the valve mechanism comprise a hollow enclosure which has contained therein a compressible structure which acts both as a filter and as a mechanism to allow for the selective flow of a liquid medium through the system in a singular direction, the capabilities of the needleless transfer system are achieved.

Abstract: The invention relates to disposable devices for introducing substances into body cavities of a patient. The device comprises a container for holding a substance which is connected to a tube ending in an opening which is inserted into a body cavity. The opening is sealed by a frangible seal located inside the opening. An actuating rod ruptures and removes the seal upon actuation. The actuating rod is provided with supporting rods extending to the container which are connected to the container by frangible connections. The supporting rod serves as a safe-guard against accidental rupture of the seal and as a guide for a controlled movement of said the actuating rod. The supporting rod also defines and protects an area to be kept sterile. The invention also relates to a moulding apparatus and to a method for making said device.

Abstract: A needleless injection device includes an initiator valve controlling flow of compressed gas into a reservoir. A poppet valve connecting to the reservoir has a gas pressure regulation end to regulate flow from the initiator valve into the reservoir. A clamp piston is driven forward by gas pressure from the reservoir and causes jaws to clamp onto a plunger extending into an ampule. The poppet valve opens when reservoir pressure reaches the cracking pressure of the poppet valve. Gas from the reservoir rushes through the poppet valve into a drive chamber and forces a drive piston, containing the clamp piston and jaws, forward causing the plunger to slide into the ampule. A jet of injectant is discharged from the nozzle of the ampule and penetrates through the patient's skin. An improved method of needleless injection uses a specific pressure profile, ampule nozzle diameter, patient, injection site, and injectant parameters.

Abstract: A hypodermic jet injector employing self-contained, patient fillable, thin-walled disposable ampules. Each ampule includes an elongate plastic body with an injection orifice at a first end, an internal propellant at a closed second end, and a double piston slidably and sealingly mounted within the body entirely between the orifice and the internal propellant, and also includes an auxiliary access opening in the ampule side wall. An ampule chamber with a corresponding access opening in its side wall is provided to receive and support the thin-walled ampule. The main body of the ampule is molded with draft angles, and the double piston construction includes a soft rubber plunger and a relatively hard plunger to the front and rear, respectively, of the auxiliary access opening in the ampule, with the two plungers interconnected by a connecting rod spanning the central section of the ampule.

Abstract: A needleless injection device has a housing containing a pilot valve connectable to a compressed gas source. A two stage power amplifying valve includes a main valve operatively connected to the pilot valve. The pilot valve and main valve form a two-stage valve with the pilot valve activatable to open the main valve utilizing gas pressure. Compressed gas in a reservoir flows through the open main valve to drive a plunger into an ampule to inject an injectant through a patient's skin. Interlocks are provided to resist inadvertent actuation of the device and a indicator indicates whether there is sufficient gas pressure in the device for another injection.

Abstract: A needleless injector for providing medication provides improved flow rate with a reduced pressure head. The injector includes discharge member having a rounded or sloped jet orifice, a milled valve member, and a check valve, which provide for increased shot velocity, reduced time of the shot and increased flow.

Abstract: An ampule containing a liquid, e.g., a dose of medicine, connects to a hand-held portable power unit containing an energy accumulator which can be charged and then discharged by manual actuation of a trigger. Preferably the energy accumulator is a compressible spring which is charged by compressing it and discharged by releasing it. The discharging accumulator powers a thruster, preferably a rod, driving it against a plunger in the ampule. The driven plunger applies pressure to the liquid in the ampule and drives the liquid through a small tapered orifice having an open mouth. During an injection, the open mouth of the orifice is pressed against an injection site so that the liquid being forced through the orifice can hypodermically penetrate the injection site. The preferred compressible spring can be charged by forcing the thruster backward against the spring, compressing it to a point where a latching device catches it and holds it compressed.

Abstract: A needless injector having a liquid metering chamber with an outlet orifice, a piston slidable within the metering chamber, and a rod arranged to strike one end of the piston to force liquid through the outlet orifice. A cam follower is mounted at one end of the rod to ride on a cam that retracts the rod away from the piston. The injector is in two parts which are biassed away from each other. The front part of the injector carries the outlet orifice and the rear part carries the cam. Actuation occurs when the two parts of the injector are sufficiently urged towards each other by the user to actuate the cam to release the rod and thereby strike the piston and force liquid through the outlet orifice.

Abstract: The device comprises a receiving housing for receiving and maintaining the vial, this latter being comprised of a pocket (10) containing the product and a nozzle (11 ) in which is inserted a pump (8) which has a variable volume chamber (8000) controlled by a movable actuating member (85); the device according to the invention comprises a pushing means (42) capable of acting against this actuating member (85) through the wall of the casing so as to displace it in a so-called "forward" direction against a resilient release means, a locking means (46) capable of locking the pushing means (42) in a position in which it maintains the actuating member in a mobile state at the end of the "forward" stroke, and an unlocking control means (52) of said locking means (46).Device for distributing successive and precise doses of a fluid product, in particular medicinal or cosmetic, for instance for the instillation of an eye lotion.

Abstract: An apparatus for the particle mediated genetic transformation of organisms in vivo has two parts, a support unit and a hand unit. The hand unit is of a convenient hand manipulable size so that it can be placed readily against the organism the cells of which are to be transformed. The hand unit is connected to the support unit by a flexible umbilical so that the hand unit can be placed where desired. The apparatus is particularly well adapted for the convenient transformation of somatic cells of whole animals or humans.

Abstract: A needleless injection device includes an initiator valve controlling flow of compressed gas into a reservoir. A poppet valve connecting to the reservoir has a gas pressure regulation end to regulate flow from the initiator valve into the reservoir. A clamp piston is driven forward by gas pressure from the reservoir and causes jaws to clamp onto a plunger extending into an ampule. The poppet valve opens when reservoir pressure reaches the cracking pressure of the poppet valve. Gas from the reservoir rushes through the poppet valve into a drive chamber and forces a drive piston, containing the clamp piston and jaws, forward causing the plunger to slide into the ampule. A jet of injectant is discharged from the nozzle of the ampule and penetrates through the patient's skin. An improved method of needleless injection uses a specific pressure profile, ampule nozzle diameter, patient, injection site, and injectant parameters.

Abstract: A needless injection device includes an initiator valve controlling flow of compressed gas into a reservoir. A poppet valve connecting to the reservoir has a gas pressure regulation end to regulate flow from the initiator valve into the reservoir. A clamp piston is driven forward by gas pressure from the reservoir and causes jaws to clamp onto a plunger extending into an ampule. The poppet valve opens when reservoir pressure reaches the cracking pressure of the poppet valve. Gas from the reservoir rushes through the popper valve into a drive chamber and forces a drive piston, containing the clamp piston and jaws, forward causing the plunger to slide into the ampule. A jet of injectant sprays out of the nozzle of the ampule and penetrates through the patient's skin.

Abstract: A measuring spoon for accurately measuring and delivering a dose of medicine to a patient. The measuring spoon includes a hollow substantially circular filler tube which is open on both ends. At one end of the filler tube a spoon is connected so as to leave an opening for pouring medicine into the filler tube. A plunger is inserted in the opposite open end and acts as a base level for medicine poured into the filler tube. The filler tube includes indicator lines each indicating a different dosage amount. In use, the plunger top is aligned with the indicator line indicating the desired dosage. The filler tube is filled with the correct dosage and the plunger is depressed to fill the spoon.

Abstract: A single use needleless hypodermic injector includes an elongate housing with a proximal end, a distal end, an axis and a hollow bore therethrough. The housing has a reservoir at the distal end with a generally cylindrical chamber for containing an injectable liquid. The chamber has a axis aligned with the housing longitudinal axis. The chamber has a first open end adjacent the housing with a resilient stopper mounted therein. The reservoir has a distal second end with an orifice in fluid communication with the chamber. The resilient stopper seals the chamber and ejects the liquid from the chamber, forming a stream at the orifice when the stopper is moved distally in the chamber. The injector has an piston mounted for axial movement within the housing bore and elements to axially bias the piston distally within the bore. The piston has an armed position wherein it is positioned proximally within the bore.

Abstract: A needleless injection device has a housing containing a pilot valve connectable to a compressed gas source. A two stage power amplifying valve includes a main valve operatively connected to the pilot valve. The pilot valve and main valve form a two-stage valve with the pilot valve activatable to open the main valve utilizing gas pressure. Compressed gas in a reservoir flows through the open main valve to drive a plunger into an ampule to inject an injectant through a patient's skin. Interlocks are provided to resist inadvertent actuation of the device and a indicator indicates whether there is sufficient gas pressure in the device for another injection. An ampule for needleless injection has a nozzle length to nozzle diameter ratio of from 2.0 to 5.0 and a throat cone flair angle of from 10-14 degrees.

Abstract: The present invention is directed to a syringe that includes a gas driven piston to force liquid medication from a syringe cartridge through a variety of injection nozzles. The syringe may be mechanically operated for loading or aspirating the syringe.

Abstract: Injector administering subcutaneous injections without a needle and with a one-shot cap. The injector (11) includes an injection head (16), a chamber (27) to contain medicament which cooperates with a piston (28), an outlet aperture (15) for the medicament, means (30) to convey the medicament into the containing chamber (27), means to compress means which expel the medicament and a cocking and trigger assembly to actuate the expulsion means. The injector may also include means to measure the quantity of medicament charged and possibly means to limit the charging. In cooperation with the injector (11) is a frontal replaceable one-shot cap (10) with a removable stopper (12) which is broken in a pre-set manner. An axially movable striker (26) is also included and has a first breakage position and a second injection position defined by the replaceable one-shot cap (10).

Abstract: In general, syringes for needleless injectors must be resonably accurately dimensioned, and the barrel of the injector must be formed of metal in order to prevent expansion of the syringe under pressure. A simple alternative is a syringe including an elongated tubular body with one open end and a closed end containing an injection orifice, and a plug slidable in the body with a prong at one end of the plug extending towards the orifice end of the body, the prong carrying an O-ring and an annular seal which prevents squeezing of the O-ring between the body of the syringe and the plug under injection pressures. An alternative form of syringe includes a pair of valves, one of which normally closes the injection orifice, and the other of which is mounted on the plug.

Abstract: An apparatus for the particle mediated genetic transformation of organisms in vivo has two parts, a support unit and a hand unit. The hand unit is of a convenient hand manipulable size so that it can be placed readily against the organism the cells of which are to be transformed. The hand unit is connected to the support unit by a flexible umbilical so that the hand unit can be placed where desired. The apparatus is particularly well adapted for the convenient transformation of somatic cells of whole animals or humans.

Abstract: A device for subcutaneous injection without a needle comprising an injection head (12) including a plurality of injection holes (38) having a diameter of less than about 100 microns, these holes being parallel to one another and being formed at the ends of larger-diameter oblique cylindrical ducts (42) made through the thickness of the injection head.

Abstract: A disposable unitary jet injector cartridge, filled with a medicament to be injected, includes an interrupted flange and collar adapted to releaseably affix the cartridge to a jet injector gun. When the gun is fired, a predetermined amount of medicament is injected from the sterile end of the cartridge without the need to sterilize either the gun or other portions of the cartridge. The cartridge is particularly useful for the self-administration of drugs and medicines by a patient.

Abstract: A dry, disposable, low-cost nozzle assembly for a spring-powered medical injector power unit comprises a generally cylindrical molded plastic nozzle body which is removably attached to a medical injector module and it includes a longitudinal bore of a predetermined diameter and terminating in a conical segment short of the end surface thereof. A counterbore of a fine diameter is then formed between the apex and the end of the nozzle member, forming the ejector orifice. A seal member fits within the bore of the nozzle body and releasably attaches to the power unit's plunger. The seal member includes a conical tip dimensioned to fit with close tolerance in the conical segment of the body portion of the nozzle.

Abstract: A liquid-injection instrument without needle comprises an elongated body in two separable parts placed end to end. The first, so-called medical part, comprises at least one cavity receiving a liquid-tight cell which contains the injection liquid and has a movable base which, when displaced, forces liquid from the cell towards at least one variable-volume dosing chamber in the medical part. This communicates with a nozzle provided with an injector capable of forming a narrow jet of liquid following forcible expulsion of liquid from the dosing chamber. The second, so-called motor part, comprises a pneumatically controlled mobile assembly which effects alternating movements. The mobile assembly comprises a working piston (52-233-420) and a control and propulsion spring (62-241-444) which acts on the piston when gradually compressed by the movement of a plunger (52-276-445) caused by the pressure of the compressed air in a gas-tight chamber (51-287) in the body.

Abstract: An ampoule is provided with openings and a flexible membrane, forming a cavity, in which medication is stored in liquid form. The membrane is extended into the front end of an injection pistol which has a spring loaded punch which upon release, empties the ampoule through the openings. The ampoule has a flat front plate which covers the front end of the injection pistol. The openings of the ampoule are formed as nozzles in short truncated cones arranged in circular fashion on the front plate.

Abstract: A system is provided that is useful for hypodermic injection of medication without piercing the skin with a needle. The system includes a gas pressure actuated needleless hypodermic injection device for injecting medication through the skin. The injection device includes an injector assembly having an injector body with a chamber for a compressed gas container and an ampule assembly mounted on the injector body for containing the liquid medication. The system also includes an adaptor assembly for use on a medication vial for transferring medication to the ampule assembly.

Abstract: A device to introduce a liquid into the hypoderma, the device includes a reservoir which receives a gas under pressure, the gas is delivered via a valve to an interacting piston and cylinder. When the gas is delivered to the piston, the piston moves to eject a liquid from a capsule mounted within the device. The liquid contained in the capsule is then ejected through a nozzle located against the skin of the user.