Means Broken, Cut, Pierced Or Torn To Permit Mixing Patents (Class 604/87)
-
Publication number: 20130110039Abstract: A syringe carpule for storing, transporting and in situ mixing of a local anesthetic, such as lidocaine, and a buffer, such as sodium bicarbonate, and delivery of buffered anesthetic solution according to the present invention that comprises a hollow tubular body received within the frame of a carpule syringe, at least one axially movable plunger within the body and configured to be engaged and moved by a rod of the carpule syringe, a seal pierced by a rear portion of a needle coupled to the carpule syringe, a first chamber within the body filled with anesthetic solution during storing and transport, a second chamber defined within the body filled with buffering solution during storing and transport; and a breachable separating member between the first and second chamber configured to be removed for in situ mixing of the buffering and the anesthetic solutions allowing for delivery of a buffered anesthetic solution.Type: ApplicationFiled: November 1, 2012Publication date: May 2, 2013Inventor: George Just
-
Patent number: 8419722Abstract: An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.Type: GrantFiled: January 5, 2007Date of Patent: April 16, 2013Assignee: Spinal Restoration, Inc.Inventors: Mark Richards, Brian D. Burkinshaw, Kevin Pauza, James B. Rogan, John Wheeler
-
Patent number: 8403923Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: August 17, 2005Date of Patent: March 26, 2013Assignee: Spinal Restoration, Inc.Inventors: Steven I. Whitlock, Brian D. Burkinshaw, Kevin Pauza
-
Patent number: 8394052Abstract: A plunger-barrel apparatus is adapted for use within a syringe-in-syringe mixing system for mixing a two-part composition (e.g., a dental composition). A hollow plunger-barrel body has a continuous cylindrical wall defining an internal chamber for containing a first component. The body includes a plunger receiving end and a dispensing end. An integral sealing plug and rupturable membrane is disposed at the dispensing end of the body and include a sealing plug portion and a rupturable membrane portion that are integrally formed together as a single piece (e.g., formed of a single piece of elastomeric material). An associated syringe-in-syringe mixing system includes a first plunger, the hollow plunger-barrel body as described above adapted to contain a first component, and a syringe barrel configured to contain a second component. When assembled, the first plunger is slidably disposed within the hollow plunger-barrel body, and the plunger-barrel body is slidably disposed within the syringe barrel.Type: GrantFiled: August 16, 2010Date of Patent: March 12, 2013Assignee: Ultradent Products, Inc.Inventors: Neil Jessop, Bruce S. McLean, Jared Sheetz
-
Patent number: 8382704Abstract: A system for delivering a cell-slurry to a patient may include a fluid, cells that are non-dissolvable or immiscible in the fluid, thereby forming the cell-slurry, a syringe adapted to contain the cell-slurry and a supernate of the cell-slurry, the syringe defining a first end having an outlet through which the cell-slurry is delivered to the patient, a fluidizing system associated with the syringe and adapted to effect dilation of the cell-slurry with a portion of the supernate, to form a dilated cell-slurry, the dilated cell-slurry being transferred from the fluidizing system to the syringe, while maintaining at least a portion of the supernate, the cell-slurry and supernate being transferred from the fluidizing system to the syringe, a pressurizing mechanism adapted to create a pressure to cause the dilated cell-slurry contained within the syringe to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system, the pressurizing mechanism and movemenType: GrantFiled: December 20, 2007Date of Patent: February 26, 2013Assignee: Medrad, Inc.Inventors: Arthur E. Uber, III, David M. Griffiths, David M. Reilly, Alan D. Hirschman, Kevin P. Cowan, Mark Trocki
-
Patent number: 8382737Abstract: Disclosed is a dispensing system a dispenser having a first chamber containing a first material and a second chamber containing a second material. The dispenser is configured to selectively retract one of the chambers at least partially within the other to transition the dispenser between an extended position and a compact position. The first chamber includes an open top end that is, before use, covered with a first breakable membrane. A breaker ring, at least initially covered with a second breakable membrane, is configured to break the breakable membranes when the dispenser is transitioned between an extended position and a compact position. In the compact position, with the membranes broken, the first material and second material are free to form a mixture that can be dispensed via an opening in the dispenser's openable tip.Type: GrantFiled: May 22, 2012Date of Patent: February 26, 2013Inventors: Rourke M. Yeakley, Charles Leslie Floyd
-
Publication number: 20130030412Abstract: A method and device for mixing substances to form a mixture that can he administered to a patient are disclosed. Such a device can include a hollow cylindrical member, a barrier sealing an opening of the member, and a tether attached to the barrier so that the harrier at least partially ruptures when the tether is pulled in a direction away from the barrier. Such a method for mixing substances can include providing a device with a first substance contained within the hollow cylindrical member. The method can also include the step of inserting the device into the barrel of an administering system, where the administering system includes a second substance, and the step of pulling the component in a direction away from the barrier such that the tether causes the barrier to at least partially rupture.Type: ApplicationFiled: September 28, 2012Publication date: January 31, 2013Applicant: GLUCAGO LLCInventor: Glucago LLC
-
Patent number: 8357147Abstract: A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc. The method includes inserting an introducer needle through the annulus fibrosus by puncturing the annulus fibrosus with the introducer needle, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition into the disc through the introducer needle directly or indirectly so that the in situ curable composition contacts a defect in the annulus fibrosus; and curing said material in situ.Type: GrantFiled: February 16, 2007Date of Patent: January 22, 2013Assignee: Spinal Restoration, Inc.Inventors: Brian D. Burkinshaw, John L. Wheeler, James B. Rogan, Steven I. Whitlock
-
Patent number: 8353866Abstract: The present invention relates to a mixing syringe device for delivering a medicament or medical composition to a site of interest. The mixing syringe device generally includes a multi-chambered open lumen and optionally a sectioned plunger. The open lumen has at least two longitudinally oriented chambers within the interior of the lumen, and the optional sectioned plunger has at least two longitudinally oriented extensions corresponding in configuration to the at least two longitudinally oriented chambers of the open lumen and configured to be reciprocatably disposed in the chambers of the open lumen. Each compartment of the lumen is configured to store a medicament component or medical composition component in its interior. In certain embodiments, each compartment is sealed at one end by a movable stopper mechanism and sealed at the other end by a sealing mechanism capable of temporarily or otherwise opening. Methods of use are also provided.Type: GrantFiled: September 8, 2009Date of Patent: January 15, 2013Assignee: Thomasevans, LLCInventor: Richard T. Evans, Jr.
-
Publication number: 20120323172Abstract: Inline liquid drug medical device having a longitudinal device axis, a housing with a linear displaceable sliding flow control member displaceable along a transverse bore from a first flow control position for establishing flow communication between a first pair of ports for liquid drug reconstitution purposes to a second flow control position for establishing flow communication between a second pair of ports for liquid drug administration purposes, and a manually operated actuating mechanism for applying a linear displacement force for urging the flow control member to slide along the bore from its first flow control position to its second flow control position.Type: ApplicationFiled: November 4, 2010Publication date: December 20, 2012Applicant: MEDIMOP Medical Projects Ltd.Inventors: Nimrod Lev, Igor Denenburg, Moshe Gilboa
-
Patent number: 8323262Abstract: Certain aspects of the invention relate to an applicator, and methods of use thereof, which can house multiple component formulations in separate material receptacles, which can then be easily reconstituted at time of use without any assembly by the user. A device of the invention can be used for, but is not limited to, applying hydrogel formulations to dura mater, abdominal tissue in hernia repair, tissues near the spine, lung tissue, intestinal tissue, and any of the internal tissues. A device of the invention can be configured to apply a spray or a stream of liquid formulation onto a surface to be treated. A device of the invention can be configured to deliver the formulation through an endoscope or laparoscope.Type: GrantFiled: July 8, 2009Date of Patent: December 4, 2012Assignee: HyperBranch Medical Technology, Inc.Inventors: Keith R. D'Alessio, Jeffrey G. Clark, Roy R. B. Attride, Wai N. Chin, Robert M. Colonna, Tomas Matusaitis, Todd J. Taylor, Christopher R. Yahnker
-
Patent number: 8317743Abstract: A method for mixing and injection and an apparatus for performing the method includes the use of a needle and a needle base, a syringe attachment element and a mixing chamber engagement assembly including a needle chamber surrounding the needle and a first liquid conduit portion, sealed from the needle chamber. A mixing chamber engagement portion includes a second liquid conduit portion communicating with the first liquid conduit portion and a mixing chamber. When the syringe attachment element and the needle base are in a first relative engagement orientation liquid can flow between an interior of the syringe and the first liquid conduit portion and upon axially displacing the needle base and syringe attachment element to a second relative engagement orientation, liquid can flow between an interior of the syringe and the needle.Type: GrantFiled: July 15, 2008Date of Patent: November 27, 2012Assignee: Medimop Medical Projects Ltd.Inventor: Igor Denenburg
-
Publication number: 20120279884Abstract: The invention includes a device having a chamber within a syringe. A fluid passageway extends through a syringe piston. A valve is associated with the passageway controlling fluid passage through the piston. The invention includes a piercing structure having a head segment and a body portion, with a channel through the body portion and through at least one surface of the head without passing through the tip. In another aspect the invention encompasses a method of preparing an agent for administration to an individual. A first component is provided within a syringe and a second component is provided within a vial. A closed valve is associated with a fluid passageway between the vial and the syringe barrel through a piston. Valve repositioning allows fluid passage and sliding of the piston joins the first and second components. Repeated sliding of the piston mixes the components to produce the medication agent.Type: ApplicationFiled: July 13, 2012Publication date: November 8, 2012Applicant: HYPROTEK, INC.Inventors: Patrick O. Tennican, Russell A. Michaelsen, L. Myles Phipps
-
Patent number: 8292846Abstract: An applicator tip for use with a fluid applicator includes a base configured for releasable engagement with a fluid applicator at a proximal end of the base. The base includes a chamber defined therein configured for retaining a mixing component therein. One or more penetrable members are disposed within the base to at least partially encloses the chamber to retain the mixing component therein. A shaft extends distally from the base and defines a longitudinal axis. The shaft has a lumen extending therethrough configured for passage of a fluid therethrough. Upon penetration of the penetrable member, fluid from the fluid applicator flows into the chamber such that the fluid and the mixing component form a mixture to be applied.Type: GrantFiled: October 28, 2010Date of Patent: October 23, 2012Assignee: Tyco Healthcare Group LPInventors: Timothy Sargeant, Arpan Desai, Joshua Stopek
-
Publication number: 20120259279Abstract: A syringe for dispensing anesthetic from a cartridge having an interior wall defining a hollow interior sized and shaped for receiving a dose of anesthetic, and a piston. The syringe includes a tubular plunger slidably received in the hollow interior of the tubular cartridge. The plunger has a hollow interior extending between a distal end shaped for engaging the piston and an open proximal end. The syringe includes a plunger rod slidably received in the hollow interior of the tubular plunger. The rod has a sharp distal end adapted to penetrate the piston, a proximal end, and a length extending between the distal end and the proximal end sized so a delivery portion of the rod extends through the piston into the cartridge when the rod is driven through the piston. The delivery portion includes a recess for receiving a buffering agent to reduce acidity of the dose of anesthetic.Type: ApplicationFiled: April 4, 2012Publication date: October 11, 2012Applicant: TYCO HEALTHCARE GROUP LPInventor: Melvin A. Finke
-
Publication number: 20120238951Abstract: Disclosed is a dispensing system a dispenser having a first chamber containing a first material and a second chamber containing a second material. The dispenser is configured to selectively retract one of the chambers at least partially within the other to transition the dispenser between an extended position and a compact position. The first chamber includes an open top end that is, before use, covered with a first breakable membrane. A breaker ring, at least initially covered with a second breakable membrane, is configured to break the breakable membranes when the dispenser is transitioned between an extended position and a compact position. In the compact position, with the membranes broken, the first material and second material are free to form a mixture that can be dispensed via an opening in the dispenser's openable tip.Type: ApplicationFiled: May 22, 2012Publication date: September 20, 2012Inventors: ROURKE M. YEAKLEY, Charles Leslie Floyd
-
Patent number: 8257301Abstract: This device comprises a tube (22) containing several substantially parallel channels extending along the entire length of tube of which one end, referred to as distal, is connected with a connection element to the patient, thereby forming a mixing chamber for the various liquids, and of which the other end, referred to as proximal, is connected to a housing (3) provided with connection means (9) for several containers each containing a liquid, wherein the housing has liquid delivery lines (7), wherein each delivery line (7) is intended to be connected to a container and to a channel of the tube (22) respectively. At least one delivery line (7) of the housing is provided with a check valve (12) intended to prevent the passage of liquid from the channel of the corresponding tube into the corresponding container.Type: GrantFiled: November 12, 2008Date of Patent: September 4, 2012Inventor: Philippe Buisson
-
Patent number: 8251958Abstract: A method and device for intradermal delivery of a reconstituted medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the medicament may be located within said chamber. At least one burstable membrane retains a medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin.Type: GrantFiled: December 10, 2010Date of Patent: August 28, 2012Assignee: Becton, Dickinson and CompanyInventors: Vincent J. Sullivan, Ronald J. Pettis, John A. Mikszta, John P. Dekker, III, Wendy D. Woodley, Anjana Bhuta Wills, Matthew S. Ferriter, C. Robin Hwang
-
Patent number: 8252228Abstract: A kit is described including at least one container including a predetermined quantity of sterilized biodegradable carriers in a powder form having a treatment agent disposed therein. The kit further includes a delivery device for delivering the predetermined quantity of sterilized biodegradable carriers with the treatment agent disposed therein to a treatment site. In other embodiments, methods are described for producing the sterilized treatment agent loaded biodegradable carriers and delivering the sterilized carriers to a treatment site.Type: GrantFiled: October 13, 2008Date of Patent: August 28, 2012Assignee: Abbott Cardiovascular Systems Inc.Inventors: Abigail Freeman, Thierry Glauser, Paul M. Consigny
-
Publication number: 20120209172Abstract: The invention relates to a process for producing a bone-regeneration material. According to the method, a bio-compatible, open-pored body is exposed to a vacuum and osteoinductive and/or osteogenic substances are absorbed into the pores of the body, for example by means of a vacuum generated therein. It is thus possible to produce a bone-regeneration material, which contains osteoinductive and/or osteogenic substances in the pores of the bio-compatible body, said substances acting as a network structure for new somatic cells that are to grow into the porous body.Type: ApplicationFiled: April 26, 2012Publication date: August 16, 2012Applicant: Synthes USA, LLCInventor: Thierry Stoll
-
Publication number: 20120209171Abstract: A cartridge or injector for holding and mixing a medical product is provided herein including a tubular body having a cylindrical wall having first and second opposing ends. The wall includes inner and outer surfaces with the inner surface having a generally constant cross-section along at least a drug mixing area. A first stopper is slidably disposed within the wall between the first and second ends, the first stopper defining a liquid-tight seal with the inner surface. A second stopper is slidably disposed within the wall between the first stopper and the first end, the second stopper defining a liquid-tight seal with the inner surface. A flexible insert is disposed at or in proximity to the second end, the insert forming a liquid-tight seal with the wall, the insert being pierceable by a medical needle or other piercing instrument. A rigid retainer is fixed to the wall having an opening therein for providing access to the insert for piercing by a medical needle.Type: ApplicationFiled: September 29, 2008Publication date: August 16, 2012Applicant: Becton, Dickinson and CompanyInventors: Lionel Vedrine, Roger W. Groskopf, Matthew Sweeney, Talpade A. Dnyanesh, Min Wei, Ruane Jeter
-
Publication number: 20120179096Abstract: The invention provides methods and apparatus for reconstituting fluids and substances and injecting the reconstituted materials. Apparatus may include an injection needle having a hub, a draw-up needle having a hub, and a safety cap for engagement with a syringe barrel or reservoir for transfer and/or reconstitution and injection of fluids. The apparatus includes engagement means for securely engaging the hubs of the needles and/or cap to minimise inadvertent pricks with either of the needles during the filling of a syringe with reconstituted materials and injecting the materials. Preferably the engagement means incorporates a channel on one hub and a protrusion on the other hub. The system may incorporate a second bore for quick draw-up of materials and fluids for injection. Preferably, the apparatus comprises of polymeric materials which can be injection moulded. The invention includes methods for drawing-up and reconstituting fluids for injection.Type: ApplicationFiled: September 24, 2010Publication date: July 12, 2012Applicant: SSB TECHNOLOGY PTY LTDInventor: Andreas Aeschlimann
-
Publication number: 20120172793Abstract: In one aspect, a fixturing member for fixing a source of flowable material relative to a pen injector so as to permit introduction of the flowable material into the pen injector is provided herein. The fixturing member includes a body having a web with opposing proximal and distal faces. A distal wall extends distally from the distal face of the web, with the distal wall at least partially encompassing a distal chamber. Features are formed on the body for removable mounting onto a pen injector. Also, features are formed on the body for mounting onto a source of flowable material, A cannula extends through the web the cannula having proximal and distal ends with a lumen extending therebetween. The distal end of the cannula is located in the distal chamber and positioned such that, with the member being mounted to a pen injector, the distal end is located to be in the pen injector.Type: ApplicationFiled: April 15, 2010Publication date: July 5, 2012Applicant: BECTON, DICKINSON AND COMPANYInventors: Richard Cronenberg, Lionel Vedrine
-
Publication number: 20120109053Abstract: An applicator tip for use with a fluid applicator includes a base configured for releasable engagement with a fluid applicator at a proximal end of the base. The base includes a chamber defined therein configured for retaining a mixing component therein. One or more penetrable members are disposed within the base to at least partially encloses the chamber to retain the mixing component therein. A shaft extends distally from the base and defines a longitudinal axis. The shaft has a lumen extending therethrough configured for passage of a fluid therethrough. Upon penetration of the penetrable member, fluid from the fluid applicator flows into the chamber such that the fluid and the mixing component form a mixture to be applied.Type: ApplicationFiled: October 28, 2010Publication date: May 3, 2012Applicant: Tyco Healthcare Group LPInventors: Timothy Sargeant, Arpan Desai, Joshua Stopek
-
Patent number: 8146586Abstract: Provided are a liquid ejection cartridge and a liquid ejection device each having a simple structure capable of surely mixing a plurality of liquids. An example of the liquid ejection cartridge includes a liquid ejection portion (12) for ejecting a liquid; a first liquid storage portion (3) which is separated from the liquid ejection portion (12) through a film (10); a second liquid storage portion (4) which is separated from the first liquid storage portion (3) through a film (9). Further, the liquid ejection cartridge further includes a first penetrating member (8) for penetrating the film (10) which separates the liquid ejection portion (12) and the first liquid storage portion (3); and a second penetrating member (7) for penetrating the film (9) which separates the first liquid storage portion (3) and the second liquid storage portion (4).Type: GrantFiled: October 16, 2006Date of Patent: April 3, 2012Assignee: Canon Kabushiki KaishaInventors: Masaya Kobayashi, Kenichi Sekine
-
Patent number: 8142414Abstract: Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.Type: GrantFiled: December 23, 2008Date of Patent: March 27, 2012Assignee: Carticept Medical, Inc.Inventors: Timothy Patrick, Richard Knostman, Carribeth Ramey, Michael Axelrod
-
Patent number: 8118788Abstract: A pre-filled hypodermic syringe includes a tubular body having two open ends and containing a fluid to be administered to a patient; a plunger which, having at one of its ends a piston mounted to slide in the tubular body, passes through the opening of the first end of the tubular body; a tip for connection in the form of a cone of the Luer or Luer-Lock type, for example for connecting to a needle or to a drip, intended to pass the fluid that is to be administered and comprising a tubular part communicating with the opening of the second end; the tip comprising an obturator connected by a frangible region to the free end of its tubular part, the syringe being made of a synthetic material and obtained by molding, the obturator being molded as one piece with the tip and the tubular body.Type: GrantFiled: January 19, 2007Date of Patent: February 21, 2012Assignee: Laboratoire AguettantInventor: Pierre Frezza
-
Publication number: 20120035537Abstract: A method of combining a drug in a first container and a liquid in a second container includes placing the first container and the second container in fluid communication with a housing, combining the liquid and the drug in the first container, transferring the liquid and the drug from the first container to the housing, and transferring the liquid and the drug from the housing to a third container.Type: ApplicationFiled: September 13, 2011Publication date: February 9, 2012Applicant: B. Braun Melsungen AGInventor: Freddie Eng Hwee Lee
-
Publication number: 20120016296Abstract: An autoinjector comprising: a first chamber for containing a dry component of a medicament; a second chamber for containing a wet component of a medicament; an axially-slidable stopper intermediate said first and second chambers; an injection needle in fluid communication with said first chamber; and a transfer needle initially disposed axially forward of said stopper, the transfer needle having a longitudinal axial bore therethrough, a closed forward or proximal end, an open rear or distal end and a radial aperture intermediate said proximal and distal ends and in fluid communication with said longitudinal axial bore; wherein said transfer needle is capable of penetrating said stopper to establish fluid communication between said first and second chambers via said bore and radial aperture to enable said wet component to mix with said dry component and wherein said injection needle is capable of delivering the mixed dry and wet components of the medicament to an injection site.Type: ApplicationFiled: August 5, 2009Publication date: January 19, 2012Inventor: Cleathero Ian Charles
-
Publication number: 20110270220Abstract: A device for administering a therapeutic substance includes a sealed package and an administration assembly. The sealed package includes a collapsible compartment containing the substance. The administration assembly includes a dispenser that is in fluid communication with the substance. At least one compression member is movable by linear actuation to progressively collapse the collapsible compartment and urge the therapeutic substance through the dispenser.Type: ApplicationFiled: March 3, 2011Publication date: November 3, 2011Applicant: AKTIVPAK, INC.Inventor: Amir Genosar
-
Publication number: 20110264037Abstract: A device for mixing and transferring is described. The device comprises a housing having open ends, a container accessing member having at least one fluid conduit therethrough, the container accessing member extending generally outwardly from one end of the housing. The device comprises a fluid delivery device accessing member having at least one fluid conduit therethrough, the fluid delivery device accessing member extending generally outwardly from the other end of the housing having the container accessing member, the fluid delivery device accessing member and the container accessing member in fluid communication therewith.Type: ApplicationFiled: August 21, 2008Publication date: October 27, 2011Inventors: David L. Foshee, Theodore J. Mosler, Bryan J. Peters, Nicholas J. Jardine, Todd M. Korogi
-
Publication number: 20110251546Abstract: A method and device for intradermal delivery of a reconstituted medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the medicament may be located within said chamber. At least one burstable membrane retains a medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin.Type: ApplicationFiled: December 10, 2010Publication date: October 13, 2011Inventors: Vincent J. Sullivan, Ronald J. Pettis, John A. Mikszta, John P. Dekker, III, Wendy D. Woodley, Anjana Bhuta Wills, Matthew S. Ferriter, C. Robin Hwang
-
Patent number: 8007469Abstract: A catheter system for positioning an instrument within a body that includes a hub defining a lumen therethrough for passage of the instrument toward the body. The catheter system also includes an elongate tubular member defining a lumen therethrough. The lumen of the elongate tubular member is in communication with the lumen of the hub for further passage of the instrument toward the body. The system also includes a slitter member that is coupled to the hub. The slitter member is disposed to slit the elongate tubular member as the elongate tubular member moves relative to the hub.Type: GrantFiled: July 30, 2008Date of Patent: August 30, 2011Assignee: Medtronic, Inc.Inventor: Niall Duffy
-
Patent number: 8002736Abstract: Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.Type: GrantFiled: December 19, 2008Date of Patent: August 23, 2011Assignee: Carticept Medical, Inc.Inventors: Timothy Patrick, Richard Knostman, Michael Axelrod, Carribeth Ramey
-
Publication number: 20110178459Abstract: Disclosed is a dispensing system a dispenser having a first chamber containing a first material and a second chamber containing a second material. The dispenser is configured to selectively retract one of the chambers at least partially within the other to transition the dispenser between an extended position and a compact position. The first chamber includes an open top end that is, before use, covered with a first breakable membrane. A breaker ring, at least initially covered with a second breakable membrane, is configured to break the breakable membranes when the dispenser is transitioned between an extended position and a compact position. In the compact position, with the membranes broken, the first material and second material are free to form a mixture that can be dispensed via an opening in the dispenser's openable tip.Type: ApplicationFiled: January 14, 2011Publication date: July 21, 2011Inventors: Rourke M. Yeakley, Charles Leslie Floyd, JR.
-
Patent number: 7980243Abstract: A cartridge for propellant-free administration of a liquid pharmaceutical composition by inhalation includes: an elongate displacing device including an upper end and a lower end, the lower end for at least partial insertion into a container; a cartridge chamber disposed at the lower end of the displacing device and operable store a pharmaceutical formulation, the cartridge chamber including at least one pierceably sealed opening; and a cannula guide extending from the upper end of the displacing device to the cartridge chamber, wherein insertion of a cannula through the guide pierces the sealed opening and releases the pharmaceutical formulation into a liquid solvent in the container to form the liquid pharmaceutical composition.Type: GrantFiled: June 7, 2007Date of Patent: July 19, 2011Assignee: Boehringer Ingelheim Pharma GmbH & Co., KGInventor: Dieter Hochrainer
-
Patent number: 7967779Abstract: A mixing syringe having a first sealed chamber containing a powder (powder housing) and a second sealed chamber containing a liquid (liquid housing). When the user needs to inject a patient, he or she holds the mixing syringe approximately upright and depresses a plunger. This motion causes a piercer to pierce a foil seal separating the two chambers. The liquid then drops down into the powder housing. The liquid flows through a passage in a piston located in the powder housing, where it then comes in contact with the powder itself. As the user continues pressing the plunger downward, the piercer comes to rest within the piston and seals the passage through the piston, thereby locking the piercer and piston together. The device is then ready for an injection. As the plunger is further depressed, the piston expels the powder and liquid mixture through a needle.Type: GrantFiled: January 11, 2008Date of Patent: June 28, 2011Inventors: Kim W. Bertron, John Wiley Horton, Brian J. Boothe
-
Patent number: 7963938Abstract: A device for producing medical foam, for example, a sclerosing agent, a diagnostic agent, a therapeutic agent, etc. The device comprises an active ingredient chamber and a gas chamber. Both chambers are respectively closed by a piston and connected to a foam generator. Both pistons are interconnected, especially by a connecting element, and can be displaced together, in order to supply the active ingredient and the gas to the foam producer.Type: GrantFiled: November 13, 2003Date of Patent: June 21, 2011Assignee: Chemische Fabrik Kreussler & Co.Inventors: Jan-Christoph Wollmann, Dorothee Schliephake
-
Patent number: 7951108Abstract: A mixing syringe and method for using the mixing syringe are provided. The mixing syringe comprises a housing having a first compartment for containing a first component, an outer plunger having a second compartment for containing a second component, and an inner plunger. Prior to use, a seal separates the first and second components. To prepare the mixture, the seal is pierced and the two components are mixed. The mixing syringe and its method of use are particularly suited to applications in which at least one of the mixture components is a relatively highly viscous material.Type: GrantFiled: September 24, 2008Date of Patent: May 31, 2011Assignee: MDC Investment Holdings, Inc.Inventors: Derek J. Harper, Charles L. Johnson, Joseph Kovalski
-
Patent number: 7951109Abstract: A storage and dispensing cap for a liquid receptacle having a cap body storage chamber for use with a receptacle such as a bottle, pouch or intravenous bag that is used to store a liquid for use with a syringe that is inserted into the receptacle for drawing the liquid contents into the syringe. A liquid, powder or capsule in the cap body chamber is mixed into the liquid receptacle for use with the syringe. A sleeve penetrator is mounted inside said cap body chamber and is sized in length to permit rupture of the bottom floor of said cap body chamber when manually depressed for dispensing whatever material is placed inside said cap body chamber and sleeve penetrator into said syringe bottle. An open passage from the cap body to the inside of the receptacle is provided once the storage chamber is ruptured by manually depressing the penetrator to allow the syringe needle end to be inserted into the liquid receptacle.Type: GrantFiled: September 22, 2006Date of Patent: May 31, 2011Assignee: Andeboh Holdings, FLPInventor: Michael R. Anderson
-
Patent number: 7946417Abstract: An apparatus and method for mixing two components and delivering the mixture to a patient. The apparatus contains a mixing chamber for mixing a liquid component and a powder component. The liquid component and powder component are mixed within the mixing chamber by rotation of a collapsible mixing element. A plunger is then advanced through the mixing chamber to force the mixture out of the mixing chamber and deliver the mixture to the patient.Type: GrantFiled: May 17, 2010Date of Patent: May 24, 2011Assignee: CareFusion 2200, Inc.Inventors: Michael Plishka, Randall Scott Koplin
-
Patent number: 7938816Abstract: The invention relates to a medical bag which is intended for the infusion of a medicament by means of gravity. The inventive bag comprises: at least two compartments, namely a first compartment (1) containing a medicament in the form of a solution and a second compartment (2) containing a rinsing solution; and means for separating/communicating the compartments, which prevent the rinsing solution from automatically entering the medicament compartment except at the end of the infusion period. The rinsing solution ends the infusion, by rinsing the medicament bag and the infusion line, such as to prevent any risk of contamination or leakage of residual medicament from the bag or line.Type: GrantFiled: April 8, 2010Date of Patent: May 10, 2011Assignee: Laboratoire AguettantInventor: Pierre Frezza
-
Publication number: 20110106053Abstract: A treatment apparatus in the form of a bag which includes a first compartment containing at least one treatment substance, a second compartment containing at least one treatment substance, at least one openable seal between the first and second compartments, wherein at least one treatment substance in the first compartment is incompatible over time with at least one treatment substance in the second compartment.Type: ApplicationFiled: August 14, 2008Publication date: May 5, 2011Inventor: Wayne Frederick Leech
-
Publication number: 20110087164Abstract: A fluid transfer device is disclosed and described, the device comprising a housing comprising a first piercing assembly associated with the housing, the first piercing assembly adapted for accessing a first container, the first piercing assembly comprising a first piercing member comprising at least one conduit. A second piercing assembly is associated with the housing, the second piercing assembly adapted for accessing a second container, the second piercing assembly comprising a second piercing member comprising at least one conduit.Type: ApplicationFiled: October 1, 2010Publication date: April 14, 2011Applicant: YUKON MEDICAL, LLCInventors: Theodore J. Mosler, Bryan J. Peters, David L. Foshee, Nathan R. Snell
-
Patent number: 7896836Abstract: A valved medicament delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of less than 10 atmospheres, a manually actuatable fluid delivery device having an outlet in fluid communication with the chamber and a manually actuated valve located between the outlet of the fluid delivery device and the chamber inlet for delivery of fluid under pressure to the valve. The medicament delivery device of this invention may be utilized to deliver a controlled unit dose of a medicament on demand by first pressurizing a pressure chamber in the pressure delivery device upstream of the valve, then opening the valve to open the membranes and express the medicament through the chamber outlet.Type: GrantFiled: April 12, 2006Date of Patent: March 1, 2011Assignee: Becton, Dickinson and CompanyInventors: Vincent J. Sullivan, Anjana Bhuta Wills
-
Patent number: 7883490Abstract: Syringe systems for mixing and delivery of particles into the body are disclosed. In some embodiments, a mixing and delivery medical syringe system can include a barrel including first and second detachable sections, and first and second compartments communicable through a conduit.Type: GrantFiled: October 23, 2002Date of Patent: February 8, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Thomas V. Casey, II, Bud Damiano
-
Patent number: 7862537Abstract: Medical device for in situ liquid drug reconstitution in medicinal vessels containing drug contents. The medical device includes a body member having a vessel port for insertion into a medicinal vessel containing drug contents, and a syringe port for receiving a syringe containing a diluent for reconstituting the drug contents into a reconstituted liquid drug. The medical device includes a one-way flow restriction mechanism between the two ports for positively restricting injection of diluent into a medicinal vessel and only slightly restricting aspiration of reconstituted liquid drug therefrom, if at all.Type: GrantFiled: February 13, 2006Date of Patent: January 4, 2011Assignee: Medimop Medical Projects Ltd.Inventors: Freddy Zinger, Igor Denenburg
-
Patent number: 7850663Abstract: A method and device for intradermal delivery of a reconstituted powdered medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the powdered medicament may be located within said chamber. At least one burstable membrane retains a powdered medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the powdered medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin.Type: GrantFiled: June 1, 2004Date of Patent: December 14, 2010Assignee: Becton, Dickinson and CompanyInventors: Vincent J. Sullivan, Ronald J. Pettis, John A. Mikszta, John P. Dekker, III, Wendy D. Woodley, Anjana Bhuta Wills, Matthew S. Ferriter, C. Robin Hwang
-
Publication number: 20100298768Abstract: Pen injection devices (10) and methods of using a pen injection device are disclosed. Pen injection devices include a sterile dual transfer spike assembly (150) including a dual transfer spike defining a fluidic pathway; a first cartridge assembly (12) including a first cartridge (20) containing a first substance; a second cartridge assembly (14) including a second cartridge (30) containing a second substance; a plunger rod (50) translatable in a first direction; and a biasing mechanism (60) configured to bias the plunger rod in a second direction opposite the first direction. Methods of using a pen injection device having a first container, a second container, a plunger rod, and a biasing mechanism include activating the pen injection device, thereby creating a fluidic pathway between the first container and the second container; and translating the plunger rod at least once, thereby transferring a first substance from one container to the other container to mix with a second substance.Type: ApplicationFiled: July 16, 2008Publication date: November 25, 2010Applicant: Amylin Pharmaceuticals, Inc.Inventors: Reynaldo B. Halili, JR., Victor Wei-Chung Chang, Phillip A. Estepa, Tyler J. Holschlag, Philip J. Simpson, David G. Matsuura
-
Publication number: 20100260007Abstract: Closed pouch comprising a wall defining an enclosed space containing carbon dioxide, and a pair of syringes contained within the enclosed space. The syringes are connected together by a syringe connector, and of the syringes contains a gas or gas mixture other than air, while the other contains a foamable liquid. Breakage of the syringe, connector and pumping of the syringes produces a foam useful in the treatment of varicose veins.Type: ApplicationFiled: June 18, 2010Publication date: October 14, 2010Applicant: BTG International LimitedInventors: Anthony David Harman, Jan Willem Marinus Mijers, Nikki Robinson