Abstract: Improved systems, methods, and devices for performing joint arthroplasty, including patient-adapted implant components and tools, as well as intraoperative measurement and optimization of joint kinematics are disclosed herein.

Abstract: A prosthesis for implantation into a mammalian body, the device comprising: (a) a prosthesis for implantation into a mammalian body that includes a sensor array comprising a plurality of sensors mounted to the prosthesis; and (b) an electronics structure for receiving signals from the sensor array and wirelessly transmitting representative signals to a remote receiver, where the plurality of sensors are operative to sense pressure, applied to the prosthesis by another object, in at least two axes generally perpendicular to one another.

Abstract: The fusion device for fusing a synovial joint of a human or animal patient, in particular a human facet joint, finger joint or toe joint, includes two pin-shaped anchorage portions (1) and arranged therebetween a stabilization portion (2). The anchorage portions (1) include a thermoplastic material which is liquefiable by mechanical vibration. The stabilization portion (2) preferably has a surface which is equipped for enhancing osseointegration. The anchorage portions (1) have a greater thickness (T1) and a greater depth (D) than the stabilization portion (2). Then the fusion device is pushed between the articular surfaces and mechanical vibration, in particular ultrasonic vibration, is applied to the proximal face (4) of the fusion device. Thereby the liquefiable material is liquefied where in contact with the bone tissue and penetrates into the bone tissue, where after re-solidification it constitutes a positive fit connection between the fusion device and the bone tissue.

Abstract: An artificial joint associated with an implant having a pair of three dimensional and structurally extending bones, each defining a contoured and opposing end face, which collectively defines a joint location. At least one plasticized and three dimensional shaped disk, such as a hardened and sanitary plastic material, is seated within a selected end cavity associated with a first of the bones. The disk exhibits an exterior surface configuration mating with an opposing end face of the other bone and which is biased, such as by a pressurized and fluid-filled bladder seated against an underside of the disc, in a contacting fashion against the other bone to establish a continuous wear surface.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.

Abstract: Photodynamic devices for stabilizing a joint are provided. In some embodiments, a photodynamic joint spacer is provided that includes an expandable member configured for attachment to a bone having an excised region; a formable bar configured for attachment to the bone along at least a portion of the expandable member; and a light-sensitive liquid passed into the expandable member to expand the expandable member, wherein the expandable member is shaped by the formable bar to a shape resembling the excised region of the bone, and wherein the light-sensitive liquid is curable upon exposure to light energy to set the expandable member in the shape resembling the excised region to form a photodynamic joint spacer.

Abstract: Methods of forming polymeric articles using plasma treated polymer resins, and orthopedic implants comprising a polymeric article wherein the polymeric article has reactive groups bonded to polymer molecules in an interior region of the polymeric article.

Abstract: A multi-component joint assembly incorporated into reconditioned end surfaces established between a first bone and opposing second bone. A first component is anchored into a reconditioned end surface of the first bone and exhibits a first exposed support surface. A second component is anchored into a reconditioned end surface of at least one of radius and ulna bones and exhibits a second exposed support surface. An intermediate component is supported in articulating fashion between the first and second anchored components. A plurality of micro debris entrapment chamber subassemblies are incorporated into the components and communicate with at least one of the articulating surfaces for isolating and capturing debris resulting from joint wear.

Abstract: An additively manufactured medical implant, comprising a metallic body having at least one porous surface configured to promote bony on-growth or in-growth of tissue, the porous surface being replicated from a high resolution scan of bone, and a biological surface coating configured to create a barrier to particulate debris, the biological surface coating being produced from a titanium porous plasma spray surface coating or a biomimetic coating.

Abstract: A surgical planning method is provided. A representation of a bone of a joint is created. The joint is moved to a first position. A first point corresponding to a first location in the joint is identified when the joint is in the first position. The joint is moved to a second position. A second point corresponding to a second location in the joint is identified, when the joint is in the second position. Bone preparation for implanting an implant on the bone is planned based at least in part on the first and second points.

Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.

Abstract: An orthopaedic prosthesis for use in a hip replacement surgery. The orthopaedic prosthesis includes a metallic foam shell and a metallic core. The metallic core includes a neck configured to receive a femoral head component and a stem extending through the metallic foam shell.

Abstract: A method of reinforcing the bone in an acetabulum for receiving a prosthetic acetabular implant includes preparing a surface of the acetabulum to receive an acetabular implant. At least one porous generally cylindrical bone reinforcement element is provided. At least one bore is drilled in an area of the acetabulum receiving the prosthetic acetabular implant for receiving at least one and preferably more reinforcement elements in the form of cylindrical pilings. The cylindrical porous bone reinforcement element is inserted in the bore such that an exposed surface of the porous bone reinforcement element is adjacent the surface of the acetabulum. The acetabular implant is then implanted with an outer surface of the acetabular implant supported by the reinforcement members.

Abstract: A pre-operative planning and manufacturing method for orthopedic surgery includes obtaining pre-operative medical image data representing a joint portion of a patient. The method also includes constructing a three-dimensional digital model of the joint portion and manufacturing a patient-specific alignment guide for the joint portion from the three-dimensional digital model of the joint portion when the image data is sufficient to construct the three-dimensional digital model of the joint portion. The patient-specific alignment guide has a three-dimensional patient-specific surface pre-operatively configured to nest and closely conform to a corresponding surface of the joint portion of the patient in only one position relative to the joint portion.

Abstract: Implantable devices for the surgical treatment of bone, and particularly to a bone defect at a joint region, and even more particularly at the subchondral bone level of the joint region, are disclosed. The implantable devices may be formed of a bone material, and configured to serve the dual functions of providing mechanical strength and structural integrity to the area to be treated, while also facilitating the dispersal of a flowable material in the same area. Associated delivery tools are also provided.

Abstract: The embodiments provide provides devices, instruments, and associated methods for treating joint pain. A joint is evaluated using magnetic resonance imaging to detect any defects in the subchondral bone. For example, using T2-weighted MRI images, bone marrow lesions or edemas can be identified, and using T1-weighted MRI images, associated regions of sclerotic bone adjacent to the bone marrow lesion can be identified. The treatment method may involve introducing a bone void filler material at the site to address the bone marrow lesion or edema, and/or drilling and inserting an implant to address the sclerotic bone, bone marrow lesion or edema, and insufficiency or stress fractures. An access path is mapped to a location in the subchondral region where the insufficiency fracture resides. The access path attempts to preserve an articular surface of the joint. A reinforcing member that stabilizes the insufficiency fracture is then implanted via the access path.

Abstract: An implantable device includes a polymeric body and a metallic first mounting strip connected to a trailing end portion of the body. The body has a leading end portion, a first side surface, a second side surface, an upper surface, a lower surface and a central opening extending through the upper and lower surfaces. The central opening has an internal surface with an internal leading surface, a first internal side surface and a second internal side surface. A first depth is defined between the leading end and the internal leading surface, a first spacing is defined between the first side surface and the first internal side surface and a second spacing is defined between the second side surface and the second internal side surface. The first spacing is substantially the same as the second spacing and the first depth is less than the first spacing.

Abstract: A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.

Abstract: An improved implant having components comprising an oxidized zirconium bearing surface adapted to decrease pain, lower friction, and minimize wear when coupled with natural femoral articular cartilage. The improved implant components also provide for reduced backside wear effects in fixed and mobile implants. The improved implant components further provide for more ideal wear coupling between components in mobile bearing implants.

Abstract: A device according to the invention for deflecting mechanical oscillations, at an oscillation receiver location may be set into oscillation along a first axis, and transmits such an oscillation into an oscillation along a second axis at an oscillation output location, wherein the first and the second axis form an angle to one another. The device in characterized essentially by the fact that it includes an elongate, bent oscillation element, on whose one end a coupling-in point and at whose other end a coupling-out point is arranged, wherein the device is designed in a manner such that the oscillation element oscillates transversally at the coupling-in point and at the coupling-out point, when the oscillation receiver location is subjected to an oscillation.

Abstract: Provided are processes comprising crosslinking polyethylene or using crosslinked polyethylene. Furthermore, the processes may include compacting and/or sintering the polyethylene. The polyethylene can comprise virgin ultrahigh molecular weight polyethylene having a weight average molecular weight of at least 1,000,000 g/mol, to provide a compacted composition comprising virgin ultrahigh molecular weight polyethylene.

Abstract: A medical prosthesis for use within the body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radicals, is described. Preferred prostheses exhibit reduced production of particles from the prosthesis during wear of the prosthesis, and are substantially oxidation resistant. Methods of manufacture of such devices and material used therein are also provided.

Abstract: The present invention relates to a multi-layer material comprising a metal or metal alloy substrate, the metal or alloy substrate being coated with an intermediate layer comprising at least one ceramic or crystalline, or partially crystalline, structure, including a metal or a metal alloy, said intermediate layer being coated with a layer of calcium phosphate having a cellular nanometric structure, and uses thereof. The present invention relates to the method for preparing such a material by autocatalytic deposition of a layer of calcium phosphate comprising a cellular nanometric surface structure.

Abstract: Medical implants, such as orthopedic implants of the type used in partial or total joint replacement procedures, for example. The implants include a porous substrate, and a bearing portion of a polymeric material, for example, which is at least partially molded within the porous substrate. The bearing portion includes a bearing surface that is exposed to an articulating component of another medical implant, and the porous metal substrate contacts the bone for osseointegration of the bone tissue into the porous substrate to anchor the implant. The porous substrate may include biodegradable carrier materials, in the form of one or more layers, that carry biologically active agents such as antibiotics and bone growth factors, for example.

Abstract: The present invention relates to pharmaceutical compositions comprising one or more amphiphilic polymer lubricants for use in association with artificial orthopaedic implants. Additionally, the invention relates to medical use of the lubricants of the invention in connection with conditions associated with artificial orthopaedic implants. The invention furthermore relates to artificial joint implants comprising the polymer lubricants according to the invention and methods for preparing such implants.

Abstract: A method and apparatus for coupling soft tissue to a prosthetic is disclosed. Soft tissue attachment pads having porous metal attachment regions and suture accepting holes are selectively positioned onto an implantable prosthetic to provide coupling locations.

Abstract: A joint resurfacing prosthetic implant system is disclosed having an anatomically-shaped implant to replace a joint at a pedal digit or finger, including a head having an elliptical bearing surface disposed for engaging the end of an adjacent bone and a seating surface opposite the bearing surface, an elongated stem extending distally from the seating surface, and a flange on the circumference of the device and extending distally from the seating surface. The flange includes one or more portals and a removed section configured to avoid impinging upon a tendon during and after implantation of the prosthetic. A specialized tool is also provided to facilitate the resection of the bone for implantation. The specialized tool includes an elliptical template having a cutting edge and a center insert that is sized and configured to match a reamer used to bore into the bone for insertion of the implant.

Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints.

Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a first component of the artificial joint prosthesis including a contact surface of the artificial joint prosthesis, the first component fabricated from at least one polymer and a plurality of magnetic particles; and a second component of the artificial joint prosthesis including at least one magnet configured to create a magnetic field within the artificial joint, the at least one magnet positioned to form a magnetic field directed to influence a location of debris including the magnetic particles in the joint to a position distinct from the bone-prosthesis interface in vivo.

Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, a artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; and a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo.

Abstract: A system is disclosed herein for providing a kinetic assessment and preparation of a prosthetic joint comprising one or more prosthetic components. The system comprises a prosthetic component including sensors and circuitry configured to measure load, position of load, and joint alignment. The system further includes a remote system for receiving, processing, and displaying quantitative measurements from the sensors. The kinetic assessment measures joint alignment under loading that will be similar to that of a final joint installation. The kinetic assessment can use trial or permanent prosthetic components. Furthermore, adjustments can be made to the applied load magnitude, position of load, and joint alignment by various means to fine-tune an installation. The kinetic assessment increases both performance and reliability of the installed joint by reducing error that is introduced by elements that load or modify the joint dynamics not taken into account by prior assessment methods.

Abstract: The invention comprises a fusion implant system for a generally u-shaped bone staple in which the staple is provided on a storage block with the two side legs in an un-splayed position, and an inserter having two triangular shaped pivoting handles has detachable tips that engage the staple on the storage block such that when the handles are aligned one over the other in a congruent position, the tips force the side legs into a splayed configuration at 90° and a sliding block holds the handles in this position to allow the staple to removed from the storage block and tamped using the inserter handles into respective bone.

Abstract: Artificial joint prosthetic components including synovial fluid deflection structures are described. Embodiments of artificial joint prosthesis include those with: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis; and at least one fluid deflection structure positioned on the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo.

Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.

Abstract: The invention relates to an implant (1) for osseous fusion between two bones, including a first portion (20) having a longitudinal axis A, for being inserted in the first bone and including a first means (24) for attaching said implant in said first bone, and a second portion (30) having a longitudinal axis B, for being inserted in the second bone and including a second means (34) for attaching said implant in said second bone, said first and second portions (20, 30) being connected by a central core (40), said central core being a solid body, the cross-section of which, in a plane perpendicular to said longitudinal axis A, has the shape of a star having at least three points (41, 42, 43), said first portion having three tabs (21, 22, 23), each tab extending along said longitudinal axis A from the free end (41a, 42a, 43a) of one of the points of said central core.

Abstract: An orthopedic prosthetic device having at least one pyrocarbon insert is provided. The prosthetic device can include a prosthetic component having an articulating surface and a bone engagement surface. The articulating surface can be formed of a material that is distinct from pyrocarbon and is arranged to receive the at least one pyrocarbon insert so as to position a pyrocarbon articulating surface of the at least one pyrocarbon insert relative to the prosthetic component articulating surface.

Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints.

Abstract: The present disclosure relates, at least in part, to a surgical implant and a method for manufacturing the surgical implant. In one embodiment, the surgical implant comprises a metallic substrate; a tantalum interlayer disposed adjacent to the metallic substrate and comprising ?-tantalum and amorphous tantalum; at least one DLC layer disposed adjacent the tantalum interlayer; wherein the amorphous tantalum has a phase gradient increasing from the metallic substrate side to the DLC side; wherein the DLC layer has a hardness value and an elastic modulus value; and wherein the hardness value has a gradient increasing away from the tantalum side; and wherein the elastic modulus value has a gradient from the tantalum side.

Abstract: Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid.

Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, a artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; and a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo.

Abstract: A layer applied to a joint defined surface including a general mat shape body exhibiting a plurality of recesses, such that abrading contact with an opposing joint surface creates debris which are entrapped within the recesses during a normal range of motion. The body can further exhibit a first harder plastic substratum and a second softer plastic surface. The recesses further incorporate undercut defined patterns selected from any of circular, linear and arcuate designs.

Abstract: A prosthetic system that includes a prosthetic implant and a support structure secured to an inner surface of a cavity of a bone is disclosed. The support structure defines a channel that extends through the length of the support structure. The prosthetic implant is received in the channel, and a portion of the prosthetic implant is secured to an inner surface of the support structure by an adhesive. The support structure may comprise a pair of partially hemispherical components arranged in spaced apart relationship thereby defining the channel between the pair of components.

Abstract: An orthopedic implant has a prosthetic joint component made, for example, of polyethylene and another component made of a titanium or titanium alloy substrate. The substrate has a first bearing surface coated with a coating made of a cobalt-chromium molybdenum alloy. The bearing surface slidably receives a second bearing surface of the prosthetic joint component. The cobalt-chromium molybdenum alloy coating forming the first bearing surface is made up of hexagonal close packed (HCP) grains having a columnar structure with a length of about 1 ?m and a width of about 0.1 ?m with the length of each HCP grains being oriented generally perpendicular to the titanium substrate bearing surface.

Abstract: A method of aligning implant components includes placing a first implant component in bone, followed by: coupling a first intermediate member to the first implant component; coupling a first alignment member to the first intermediate member; rotating the members as a unit to place the first intermediate member in an alignment position; removing the first alignment member from the first intermediate member; coupling a second alignment member to a second intermediate member; coupling the second intermediate member to the first intermediate member and rotating the second alignment member and the second intermediate member as a unit relative to the first intermediate member to provide a desired orientation of the second intermediate member. An alignment system for aligning first and second members includes a first alignment member having an offset channel dimensioned to receive the first member, and a second alignment member having a channel dimensioned to receive the second member.

Abstract: Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid.

Abstract: Disclosed herein are methods, compositions and tools for repairing an articular joint having a failed implant. The articular repair systems are customizable or highly selectable by or adaptable to individual patients and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by or adaptable to individual patients to increase the speed, accuracy and simplicity of performing total or partial arthroplasty including revision surgeries.

Abstract: The joint implant manufacturer obtains and compiles surgeon-specific surgical and supply preference information in relation to a supplied joint implant prior to surgery. The manufacturer designates and trains at least one surgical team member using the surgeon-specific preference information and then supplies the service of the surgical team member(s) together with the supplied joint implant and supplies. The surgical team member(s) perform surgical procedures on the patient to assist the surgeon in removing a defective joint and replacing it with the supplied implant in accordance with the surgeon's surgical preferences.

Abstract: An orthopaedic implant for filling voids in bones, and methods of using the same. The orthopaedic implant comprises an open porous metal component, having pores for promoting bone regeneration, and a resorbable bone growth promoting component which is resorbed into new bone. The orthopaedic implant and methods of the present disclosure provide structural support for the bone as well as osteoconductive and/or osteoinductive matrix for promoting bone re-growth within bone void. Advantageously, the orthopaedic implants and methods disclosed herein are useful in filling critically sized bone voids.

Abstract: Implantable components configured to be secured to a recipient with a bonding agent are presented herein. The implantable components are configured to be implanted adjacent to a recipient's bone and/or tissue and have a surface for attachment to the bonding agent.

Abstract: Deformable joint implants with a generally hyperbolic paraboloid shape are disclosed, including configurations for delivery into the small joints of the body in the wrists, hands, ankle and feet, such as the first carpo-metacarpal joint, which comprises a double-saddle structure. The center of the implant may be supported, or supported and configured as a central opening. Implants with supported center regions may have a uniform or non-uniform thickness. A region of non-uniform, reduced thickness may be circular, oval or ring-like in shape, with a central support that may have an increased thickness relative to the perimeter region of the implant.