Polycarboxylic Patents (Class 562/590)
  • Patent number: 10611716
    Abstract: Disclosed is a method of preparing adipic acid from d-glucaro-1,4:6,3-dilactone, particularly using a rhenium catalyst and a noble metal catalyst. Further the method may include using an environmentally friendly solvent such as water. Thus, the obtained adipic acid may have high purity as a final product and economic efficiency of the preparation process may be improved.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: April 7, 2020
    Assignees: Hyundai Motor Company, Kia Motors Corporation
    Inventor: Chae Hwan Hong
  • Patent number: 10487176
    Abstract: The present invention provides a method for preparing nylon salt, which comprises mixing 1,5-pentanediamine, water and dicarboxylic acid at a temperature of 65 to 120° C. to obtain a nylon salt, wherein the amount of the water is 2% to 12% by weight based on the total weight of the 1,5-pentanediamine and the dicarboxylic acid. The present invention also provides a nylon salt. According to the present method for preparing nylon salt, the incomplete reaction between the 1,5-pentanediamine and the dicarboxylic acid, which is caused by the nylon salt present during the preparation in a solid state, can be avoided; the reaction between the 1,5-pentanediamine and the dicarboxylic acid can be significantly speeded up, and the reaction time is accordingly shorten. Consequently, the content of diamine and dicarboxylic acid remained in the resulting nylon salt is very low. In addition, the final nylon salt product, which present in a solid state, makes it easier to be stored and transported.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: November 26, 2019
    Assignees: Cathay Biotech Inc., CIBT America Inc.
    Inventors: Chen Yang, Bingbing Qin, Yi Zheng, Charlie Liu, Naiqiang Li, Xiucai Liu
  • Patent number: 10479755
    Abstract: Methods of carrying out metathesis reactions of natural oil-derived polyenes (e.g., dienes and trienes), including functionalized polyenes, are generally disclosed herein. In some embodiments, the dienes or trienes contain a terminal carbon-carbon double bond, and the metathesis reaction is selective toward reaction of the terminal carbon-carbon double bonds in the polyene. Compounds made by such methods are also generally disclosed herein.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: November 19, 2019
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Keith M. Wampler, Jane Uy, Steven A. Cohen
  • Patent number: 10370319
    Abstract: Process for the manufacture of an adipic acid product by a reduction of a tetrahydrofuran dicarboxylic acid compound, wherein the tetrahydrofuran dicarboxylic acid compound is contacted with hydrogen iodide at a temperature of at least 100° C. in an inert atmosphere to yield the adipic acid product.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: August 6, 2019
    Assignee: Avantium Knowledge Centre B.V.
    Inventors: Gerardus Johannes Maria Gruter, Jan Cornelis Van Der Waal, Lisette Magnee
  • Patent number: 10314798
    Abstract: The present invention is directed to tablets for oral administration to a subject, comprising a therapeutically effective amount of SYN120 or a pharmaceutically acceptable salt thereof, wherein the tablet is substantially free of lactose. The present invention is also directed to methods for treating diseases or conditions including Alzheimer's disease and/or Parkinson's disease, comprising administering to a patient in need thereof tablets regarding the same.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: June 11, 2019
    Assignee: Biotie Therapies, Inc.
    Inventors: Christopher G. Salentine, Thomas R. Malefyt
  • Patent number: 9670125
    Abstract: High-purity dibasic acid compositions are generally disclosed. In some embodiments, the dibasic acid compositions are solutions or suspensions. In some other embodiments, the compositions are solid-state compositions. In some such embodiments, the solid-state compositions comprise a dibasic acid as a crystalline solid and further comprise a low quantity of certain impurities, such as monobasic acids, various esters, and the like. Methods and systems for making such high-purity dibasic acid compositions are also disclosed.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: June 6, 2017
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Alpeshkumar K. Patel, Yenamandra Viswanath
  • Patent number: 9561999
    Abstract: The invention relates to a method for the continuous production of a solution of salts, in particular for the production of hexamethylenediamine adipate and a device for implementing such a method. According to the invention, it is proposed to convert, in a first step, a substoichiometric quantity of alkane diamine in a ratio to the alkane dicarboxylic acid in water and, in a subsequent second step, to implement making-up with alkane diamine, adjustment of the stoichiometric ratios being effected via a pH value measurement at a constant temperature.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: February 7, 2017
    Assignee: UHDE INVENTA-FISCHER GMBH
    Inventors: Ekkehard Siebecke, Mirko Bär, Eberhard Raue
  • Patent number: 9328133
    Abstract: The present invention discloses a novel form of ferric organic compounds, including a form of ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. The ferric organic compounds of the present invention can be delivered effectively by oral route with better delivery to treat patients suffering from hyperphosphatemia, metabolic acidosis and other disorders responsive to ferric organic compound therapy.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: May 3, 2016
    Assignee: Panion & BF Biotech Inc.
    Inventors: David W. K. Kwok, Nikolay Mintchev Stoynov
  • Patent number: 9309181
    Abstract: A method of producing an unsaturated acid from a salt of a hydroxycarboxylic acid, the method includes providing an aqueous solution including a salt of a hydroxycarboxylic acid; adding a solvent with a boiling point of 200° C. or higher to the aqueous solution; and heating the aqueous solution at a temperature lower than the boiling point of the solvent to split a salt from the salt of the hydroxycarboxylic acid while simultaneously dehydrating the hydroxycarboxylic acid, thereby converting the hydroxycarboxylic acid to the unsaturated acid.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: April 12, 2016
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jun Chwae, Hyeon su Heo, Seung joon Hwang, Nam soo Park, Moo ho Lee, Kwang myung Cho
  • Patent number: 9133422
    Abstract: Provided is a copolymer aqueous solution which exerts a high calcium carbonate-deposition suppressing ability even under high hardness condition, has excellent storage stability, and suppresses coloring of a detergent to yellow even when used as a detergent raw material.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: September 15, 2015
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Takahiro Tsumori, Masato Nakano
  • Patent number: 9035094
    Abstract: Processes are disclosed for the conversion of 1,6-hexanediol to adipic acid employing a chemocatalytic reaction in which 1,6-hexanediol is reacted with oxygen in the presence of particular heterogeneous catalysts including at least one of platinum or gold. The metals are preferably provided on a support selected from the group of titania, stabilized titania, zirconia, stabilized zirconia, silica or mixtures thereof, most preferably zirconia stabilized with tungsten. The reaction with oxygen is carried out at a temperature from about 100° C. to about 300° C. and at a partial pressure of oxygen from about 50 psig to about 2000 psig.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: May 19, 2015
    Assignee: Rennovia, Inc.
    Inventors: Eric L. Dias, Vincent J. Murphy, James A. W. Shoemaker
  • Publication number: 20150119602
    Abstract: High-purity dibasic acid compositions are generally disclosed. In some embodiments, the dibasic acid compositions are solutions or suspensions. In some other embodiments, the compositions are solid-state compositions. In some such embodiments, the solid-state compositions include a dibasic acid as a crystalline solid and further include a low quantity of certain impurities, such as monobasic acids, various esters, and the like. Methods and systems for making such high-purity dibasic acid compositions are also disclosed.
    Type: Application
    Filed: September 30, 2014
    Publication date: April 30, 2015
    Applicant: Elevance Renewable Sciences, Inc.
    Inventors: Alpeshkumar K. Patel, Brian Pease, Bradon J. Dreyer, Brian Albert, Colin Huie, Yenamandra Viswanath, Purvi Kapasi, Chander Balakrishnan, Steven A. Cohen, Thomas E. Snead, Demond L. Gildon
  • Patent number: 9017812
    Abstract: A process of producing polylactic acid-based resin microparticles includes a dissolving process that forms a system, which can cause phase separation into two phases of a solution phase mainly composed of polylactic acid-based resin (A) and a solution phase mainly composed of polymer (B) different from polylactic acid-based resin, by dissolving the polylactic acid-based resin (A) and the polymer (B) different from polylactic acid-based resin in an ether-based organic solvent (C), an emulsion-forming process that forms an emulsion by applying a shear force to the system, and a microparticle-forming process that precipitates polylactic acid-based resin microparticles by contacting the emulsion with a poor solvent which has lower solubility of the polylactic acid-based resin (A) than the ether-based organic solvent (C).
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: April 28, 2015
    Assignee: Toray Industries, Inc.
    Inventors: Hiroshi Takezaki, Hiroshi Kobayashi, Makiko Saito, Itaru Asano
  • Patent number: 9012689
    Abstract: The present invention relates to a compound of formula A, wherein R is alkyl. Compound A may be used as an intermediate in the preparation of O-desmethyl venlafaxine or a salt thereof, and the present invention provides such a preparation, as well as a process for preparing the compound of formula A.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: April 21, 2015
    Assignee: Cipla Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Manohar Raghunath Surve
  • Publication number: 20150105585
    Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial ?-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
    Type: Application
    Filed: October 24, 2014
    Publication date: April 16, 2015
    Inventor: Charles R. Roe
  • Patent number: 9006484
    Abstract: A polymer having bis(diphenylphosphino)binaphthyl groups that can be used as a catalyst for an addition reaction, especially an asymmetric 1,4-addition reaction, or a reduction reaction, especially an asymmetric reduction reaction, and that can be easily recovered and recycled. The polymer having the bis(diphenylphosphino)binaphthyl groups is one resulting from repetition of a racemic or optically active 2,2?-bis(diphenylphosphino)-1,1?-binaphthyl compound substituted at 5-position thereof with an unsaturated terminal of one (meth)acryloyl group of a compound having multiple (meth)acryloyl groups, that another 2,2?-bis(diphenylphosphino)-1,1?-binaphthyl compound of a next unit is substituted at 5?-position thereof with an unsaturated terminal of another (meth)acryloyl group of the compound having multiple (meth)acryloyl groups so as to have a molecular weight of 1500 to 10000. The reduction catalyst comprises this polymer and a transition metal.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: April 14, 2015
    Assignee: Kyoeisha Chemical Co., Ltd.
    Inventors: Toyoshi Shimada, Naomi Takenaka, Gakuto Goshima, Hiroyuki Hosoi
  • Publication number: 20150057455
    Abstract: Methods and systems for producing high purity 3-hydroxypropionic acid (3-HP) from an aqueous medium, such as a fermentation broth, are described. Aqueous 3-HP solution can be purified by flash evaporation wherein the 3-HP is vaporized at an elevated temperature without conversion to acrylic acid. This process can be integrated with downstream processes for producing other chemical and consumer products.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 26, 2015
    Inventors: Cindy HOPPE, Sarah M. HOYT, Robert TENGLER, David DeCOSTER, Bradley HARKRADER, Patrick H. AU-YEUNG, Sanjib BISWAS, Pedro R. VARGAS, II, Raymond P. ROACH, Timothy Charles FRANK
  • Publication number: 20150057425
    Abstract: The present invention relates to a process for recovering succinic acid in crystal form from a fermentation broth comprising succinic acid, comprising the steps of a) bringing the fermentation broth to a pH of between 1 and 4, b) crystallizing the succinic acid from the fermentation broth to form succinic acid crystals, c) dissolving the succinic acid crystals at a temperature of between 30 and 90 degrees Celsius to form an aqueous solution comprising dissolved succinic acid, d) crystallizing the succinic acid from the solution to recover succinic acid in crystal form. The invention further relates to succinic acid in crystal form, comprising a sugar content of 1 to 100 ppm and a nitrogen content of 1 to 80 ppm.
    Type: Application
    Filed: October 30, 2014
    Publication date: February 26, 2015
    Inventors: Maarten Job VAN DE GRAAF, Fredoen VALIANPOER, Guillaume FIEY, Loic DELATTRE, Elisabeth Agnes Michele SCHULTEN
  • Publication number: 20150048495
    Abstract: An adhesive for a semiconductor, comprising an epoxy resin, a curing agent, and a compound having a group represented by the following formula (1): wherein R1 represents an electron-donating group.
    Type: Application
    Filed: October 1, 2012
    Publication date: February 19, 2015
    Inventors: Kazutaka Honda, Akira Nagai, Makoto Satou
  • Patent number: 8951986
    Abstract: The invention is related to salts of anti-viral compounds, compositions containing such salts, and therapeutic methods that include the administration of such salts, as well as to processes and intermediates useful for preparing such salts.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: February 10, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Benjamin R. Graetz, Richard Polniaszek
  • Patent number: 8940934
    Abstract: An object of the present invention is to provide a production process of an ?-hydroxy acid having a sufficient quality as a polymer raw material, which process does not produce a large amount of waste as a byproduct and is economical. The present invention provides a production process of an ?-hydroxy acid having a step of adding a basic metal to an ?-hydroxy acid ammonium salt to yield an ?-hydroxy acid metal salt and a step of desalting the ?-hydroxy acid metal salt to yield the ?-hydroxy acid.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: January 27, 2015
    Assignee: Asahi Kasei Chemicals Corporation
    Inventors: Makoto Okamoto, Hideki Date
  • Publication number: 20150018490
    Abstract: Provided is a surface-treated carbon nanotube having few surface fractures, not reducing the molecular weight of the resin to be mixed and having excellent extrudability. In the surface-treated carbon nanotube, the thermal reduction amount at 600° C. in a nitrogen atmosphere is 0.2 to 40%, the surface oxygen concentration measured by X-ray photoelectron spectroscopy (XPS) is 1.5 to 40 atm % and the surface sulfur concentration is less than 0.1 atm %.
    Type: Application
    Filed: March 5, 2013
    Publication date: January 15, 2015
    Inventors: Aya Takagiwa, Teruaki Sakuma, Yasukazu Shikano, Kazuya Noda
  • Patent number: 8933123
    Abstract: The present invention discloses polymorphic forms of O-desmethyl-venlafaxine succinate and processes for the preparation thereof.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: January 13, 2015
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Rushikesh Udaykumar Roy
  • Patent number: 8933271
    Abstract: An improved process for preparing ammonium salts from fumaric or succinic acid, is described. The method consists of neutralizing the corresponding acid carbonate or ammonium bicarbonate at a molar stoichiometric or greater than the stoichiometric ratio of 4-5% in a saturated aqueous solution of the synthesized salt at a temperature not exceeding 40° C., followed by separation of the product and drying at a temperature not exceeding 70° C. After separation of the ammonium salts, the filtrate can be re-used. Isolation of the product is usually carried out by cooling the reaction mixture to a temperature of 15-18 C.°. The product comes out in almost crystalline form. Saturated aqueous solution of the synthesized salt is formed by the interaction of carbonate or ammonium bicarbonate with the appropriate acid at a temperature not exceeding 40° C. It is possible to obtain cleaner salt concentration weighing more than 99% and not yielding lower than 98%.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: January 13, 2015
    Assignee: Lunada Biomedical, LLC
    Inventors: Roman Anatolievich Trunin, Mikhail Lvovich Uchitel, Evgenij Iljich Maevskij, Donna Kasseinova, Galina Nikolaevna Ermakova, Svetlana Yakovlevna Chernitzkaya
  • Patent number: 8927768
    Abstract: The present invention generally relates to processes for the chemocatalytic conversion of a carbohydrate source to an adipic acid product. The present invention includes processes for the conversion of a carbohydrate source to an adipic acid product via a furanic substrate, such as 2,5-furandicarboxylic acid or derivatives thereof. The present invention also includes processes for producing an adipic acid product comprising the catalytic hydrogenation of a furanic substrate to produce a tetrahydrofuranic substrate and the catalytic hydrodeoxygenation of at least a portion of the tetrahydrofuranic substrate to an adipic acid product. The present invention also includes products produced from adipic acid product and processes for the production thereof from such adipic acid product.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: January 6, 2015
    Assignee: Rennovia, Inc.
    Inventors: Thomas R. Boussie, Eric L. Dias, Zachary M. Fresco, Vincent J. Murphy
  • Publication number: 20140371314
    Abstract: This invention relates to deuterated tetramethyl dioic acids, compositions comprising them and uses thereof in the treatment of Metabolic Syndrome and any diseases, disorders or symptoms associated therewith.
    Type: Application
    Filed: December 6, 2012
    Publication date: December 18, 2014
    Inventor: Jacob Bar-Tana
  • Publication number: 20140371487
    Abstract: A method of oxidative molecular cleavage of a fatty compound, includes: —forming a liquid composition, referred to as a fatty composition, consisting of at least one aliphatic carboxylic acid, the fatty composition including the fatty compound; characterised in that it then involves: —adding, to the fatty composition, a solution of at least one quaternary ammonium salt in water capable of forming an emulsion from the fatty compound and water, then; —adding, to the emulsion, a liquid solution of at least one tungstophosphoric acid in a composition including hydrogen peroxide (H2O2), in such a way as to form, in situ in the emulsion, a quantity of a phase-transfer catalyst, formed from tungstophosphoric acid and at least one quaternary ammonium from the quaternary ammonium salt(s), and to allow the oxidative molecular cleavage of the fatty compound.
    Type: Application
    Filed: December 21, 2012
    Publication date: December 18, 2014
    Applicants: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE
    Inventors: Anaïs Godard, Sophie Thiebaud Roux, Pascale De Caro, Emeline Vedrenne, Zéphirin Mouloungui
  • Publication number: 20140357877
    Abstract: A method for preparing a carboxylic acid, includes the steps of: providing magnesium carboxylate, wherein the carboxylic acid corresponding with the carboxylate is selected from the group made of 2,5-furandicarboxylic acid, fumaric acid, adipic acid, itaconic acid, citric acid, glutaric acid, maleic acid, malonic acid, oxalic acid and fatty acids having more than 10 carbon atoms; acidifying the magnesium carboxylate with hydrogen chloride (HCl), thereby obtaining a solution including carboxylic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution including carboxylic acid and MgCl2 is concentrated; and precipitating the carboxylic acid from the solution including the carboxylic acid and MgCl2, thereby obtaining a carboxylic acid precipitate and a MgCl2 solution.
    Type: Application
    Filed: August 16, 2012
    Publication date: December 4, 2014
    Applicant: PURAC BIOCHEM B.V.
    Inventors: André Banier De Haan, Jan Van Breugel, Paulus Loduvicus Johannes Van Der Weide, Peter Paul Jansen, José María Vidal Lancis, Agustín Cerdà Baró
  • Patent number: 8901349
    Abstract: The present invention discloses a novel form of ferric organic compounds, including a form of ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. The ferric organic compounds of the present invention can be delivered effectively by oral route with better delivery to treat patients suffering from hyperphosphatemia, metabolic acidosis and other disorders responsive to ferric organic compound therapy.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: December 2, 2014
    Assignee: Panion & BF Biotech Inc.
    Inventors: David W. K. Kwok, Nikolay Mintchev Stoynov
  • Patent number: 8895779
    Abstract: A process for making MAA from a clarified DAA-containing fermentation broth includes (a) distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAA, at least some DAA, and at least about 20 wt. % water; (b) cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a DAA-containing liquid portion in contact with a MAA-containing solid portion that is substantially free of DAA; (c) separating the solid portion from the liquid portion; and (d) recovering the solid portion.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: November 25, 2014
    Assignee: BioAmber Inc.
    Inventors: Olan S. Fruchey, Leo E. Manzer, Dilum Dunuwila, Brian T. Keen, Brooke A. Albin, Nye A. Clinton, Bernard D. Dombek
  • Patent number: 8883945
    Abstract: A compound of the formula R1.[(AO)n.—R2]m (I) where: R1 is the residue of a group having at least m active hydrogen atoms; AO is an alkylene oxide residue; each n is independently from 1 to 100; m is at least 2; and each R2 is independently H, a C1 to C21 hydrocarbyl, or an acyl group —OC.R3, where R3 is a C1 to C21 hydrocarbyl group, wherein on average greater than one of the R2 groups is or comprises a C4 to C21 hydrocarbyl group comprising at least two ethylenic double bonds. The compounds are particularly suitable for use in preparing aqueous emulsions or dispersions of resins and polymers, especially alkyd resins.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: November 11, 2014
    Assignees: Croda International PLC, Croda Americas LLC
    Inventors: William Harry McNamee, Trevor Graham Blease, Johnny Denis Grade, Hanamanthsa Shankarsa Bevinakatti
  • Publication number: 20140329916
    Abstract: Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as adipate, 6-aminocaproate, hexamethylenediamine or caprolactam. Also provided herein are methods for using such an organism to produce adipate, 6-aminocaproate, hexamethylenediamine or caprolactam.
    Type: Application
    Filed: December 16, 2013
    Publication date: November 6, 2014
    Applicant: Genomatica, Inc.
    Inventors: Anthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
  • Publication number: 20140316098
    Abstract: In a process for producing phenol, a composition comprising an alkylaromatic compound is contacted with an oxygen-containing stream in the presence of an oxidation catalyst comprising a cyclic imide under oxidation conditions effective to oxidize 15 wt % or less of the alkylaromatic compound based upon the total weight of the composition and produce an oxidation product comprising unreacted alkylaromatic compound and alkylaromatic hydroperoxide in a molar ratio of 6:1 to 100:1. Thereafter, at least a portion of the oxidation product is contacted with an acidic molecular sieve catalyst under cleavage conditions effective to convert at least a portion of the alkylaromatic hydroperoxide into phenol and cyclohexanone.
    Type: Application
    Filed: December 15, 2011
    Publication date: October 23, 2014
    Applicant: ExxonMobil chemical Patents Inc.
    Inventors: Kun Wang, Roberto Garcia, Jihad M. Dakka, Gabor Kiss
  • Patent number: 8846976
    Abstract: The present invention discloses a novel form of ferric organic compounds, including a form of ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. The ferric organic compounds of the present invention can be delivered effectively by oral route with better delivery to treat patients suffering from hyperphosphatemia, metabolic acidosis and other disorders responsive to ferric organic compound therapy.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: September 30, 2014
    Assignee: Panion & BF Biotech Inc.
    Inventors: David W. K. Kwok, Nikolay Mintchev Stoynov
  • Patent number: 8846761
    Abstract: Gemcabene, a carboxyalkylether, is effective in the treatment and prevention of pancreatitis in subjects. The compound can be administered in an effective dose as the free acid, a pharmaceutically acceptable salt, or an ester or pro-drug that is hydrolyzed or otherwise metabolized in situ to gemcabene as the free acid or salt thereof.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: September 30, 2014
    Assignee: Michigan Life Therapeutics, LLC
    Inventor: Charles L. Bisgaier
  • Patent number: 8834743
    Abstract: Aliphatic dicarboxylate Gemini surfactants and lyotropic liquid crystal compositions formed thereby are disclosed. The Gemini surfactants are capable of robustly forming Q phase morphologies over broad ranges of temperature and concentration.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: September 16, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mahesh Kalyana Mahanthappa, Gregory Paul Sorenson, Keiva LaNee Coppage
  • Publication number: 20140249059
    Abstract: A composition of an oil-soluble ionic detergent that does not contribute metal ions to the composition, and which comprises a quaternary non-metallic pnictogen cation and an organic anion having at least one hydrocarbyl group of sufficient length to impart oil solubility to the detergent, the detergent having a total base number (TBN) to total acid number (TAN) ratio of at least 2:1 imparts ash-free basicity to a lubricant composition.
    Type: Application
    Filed: May 14, 2014
    Publication date: September 4, 2014
    Inventors: Ewan E. Delbridge, Virginia A. Carrick, John K. Pudelski, Matthew D. Giesleman, Christopher L. Friend, Patrick E. Mosier, Michele M. Rogers, Mark T. Tierney
  • Publication number: 20140249330
    Abstract: The invention relates to a method for the continuous production of a solution of salts, in particular for the production of hexamethylenediamine adipate and a device for implementing such a method. According to the invention, it is proposed to convert, in a first step, a substoichiometric quantity of alkane diamine in a ratio to the alkane dicarboxylic acid in water and, in a subsequent second step, to implement making-up with alkane diamine, adjustment of the stoichiometric ratios being effected via a pH value measurement at a constant temperature.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 4, 2014
    Applicant: UHDE INVENTA-FISCHER GMBH
    Inventors: Ekkehard Siebecke, Mirko Bär, Eberhard Raue
  • Publication number: 20140243247
    Abstract: A composition of an oil-soluble ionic detergent that does not contribute metal ions to the composition, and which comprises a quaternary non-metallic pnictogen cation and an organic anion having at least one hydrocarbyl group of sufficient length to impart oil solubility to the detergent, the detergent having a total base number (TBN) to total acid number (TAN) ratio of at least 2:1 imparts ash-free basicity to a lubricant composition.
    Type: Application
    Filed: May 14, 2014
    Publication date: August 28, 2014
    Applicant: The Lubrizol Corporation
    Inventors: Ewan E. Delbridge, Virginia A. Carrick, John K. Pudelski, Matthew D. Giesleman, Christopher L. Friend, Patrick E. Mosier, Michele M. Rogers, Mark T. Tierney
  • Publication number: 20140235815
    Abstract: Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as succinate. Also provided herein are methods for using such an organism to produce succinate.
    Type: Application
    Filed: October 21, 2013
    Publication date: August 21, 2014
    Applicant: Genomatica, Inc.
    Inventors: Anthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
  • Patent number: 8809582
    Abstract: The present invention relates to an economic process for preparing surface-reacted calcium carbonate. The present invention further relates to a surface-reacted calcium carbonate having an increased specific BET surface area, and the use of a process for adjusting the specific BET surface area.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: August 19, 2014
    Assignee: Omya International AG
    Inventors: Patrick A.C. Gane, Daniel E. Gerard, Joachim Schölkopf
  • Publication number: 20140206901
    Abstract: The invention relates to methods for the production of chemical compounds, particularly but not exclusively ethanol, by microbial fermentation. Also described are genetically modified micro-organisms capable of using carbon monoxide to produce one or more products, particularly but not exclusively ethanol as a main product, and producing a reduced amount or substantially no 2,3-butanediol and/or a precursor thereof.
    Type: Application
    Filed: January 31, 2013
    Publication date: July 24, 2014
    Inventors: Michael Koepke, Shilpa Nagaraju, Wendy Yiting Chen
  • Patent number: 8785687
    Abstract: The present invention relates to an economic process for preparing surface-reacted calcium carbonate. The present invention further relates to a surface-reacted calcium carbonate having an increased specific BET surface area, and the use of a process for adjusting the specific BET surface area.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: July 22, 2014
    Assignee: Omya International AG
    Inventors: Patrick A. C. Gane, Daniel E. Gerard, Joachim Schölkopf
  • Patent number: 8754257
    Abstract: The present invention discloses a pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: June 17, 2014
    Assignee: Panion & BF Biotech Inc.
    Inventors: Keith Chan, Winston Town
  • Patent number: 8754258
    Abstract: The present invention discloses a novel form of ferric organic compounds, including a form of ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. The ferric organic compounds of the present invention can be delivered effectively by oral route with better delivery to treat patients suffering from hyperphosphatemia, metabolic acidosis and other disorders responsive to ferric organic compound therapy.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: June 17, 2014
    Assignee: Panion & BF Biotech Inc.
    Inventors: David W. K. Kwok, Nikolay Mintchev Stoynov
  • Publication number: 20140148569
    Abstract: In a process for oxidizing a feed comprising cyclohexylbenzene, the feed is contacted with oxygen and an oxidation catalyst in a plurality of reaction zones connected in series, the contacting being conducted under conditions being effective to oxidize part of the cyclohexylbenzene in the feed to cyclohexylbenzene hydroperoxide in each reaction zone. At least one of the plurality of reaction zones has a reaction condition that is different from another of the plurality of reaction zones. The different reaction conditions may include one or more of (a) a progressively decreasing temperature and (b) a progressively increasing oxidation catalyst concentration as the feed flows from one reaction zone to subsequent reaction zones in the series.
    Type: Application
    Filed: August 16, 2011
    Publication date: May 29, 2014
    Applicant: ExxonMobil Chemical Patents Inc.
    Inventors: Jihad Mohammed Dakka, Francisco Manuel Benitez, Bryan Amrutlal Patel, Edmund John Mozeleski
  • Publication number: 20140131283
    Abstract: A method for treating in an industrial water treatment system for at least two of metal corrosion inhibition, scale inhibition, suspended matter dispersion, biocide efficacy, or biofilm removal/biofilm dispersion is taught by the use of at least one compound which is a salt derived from a thioamine or an oxyamine and an acid.
    Type: Application
    Filed: March 28, 2013
    Publication date: May 15, 2014
    Applicant: AMSA, INC.
    Inventors: Attila G Relenyi, Anthony P Haag
  • Publication number: 20140087978
    Abstract: A method of converting an inactive biocide into an active biocide comprises: contacting the inactive biocide with an activating agent, wherein the activating agent is capable of chemically reacting with the inactive biocide; and causing or allowing a chemical reaction to take place between the inactive biocide and the activating agent, wherein the chemical reaction produces the active biocide. The methods can also include deactivating the active biocide via a chemical reaction between the active biocide and a deactivating agent.
    Type: Application
    Filed: September 27, 2012
    Publication date: March 27, 2014
    Applicant: HALLIBURTON ENERGY SERVICES, INC
    Inventor: Jay P. DEVILLE
  • Patent number: 8680146
    Abstract: The present invention relates to salts, polymorphs and hydrates of 2-Amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diol, and to the use thereof, in particular in the treatment or prevention of various autoimmune conditions.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: March 25, 2014
    Assignee: Novartis AG
    Inventors: Guido Jordine, Michael Mutz
  • Patent number: 8669392
    Abstract: A process for preparing 2,3-di(non-linear-alkyl)-2-cyanosuccinate compounds, especially 2,3-diisopropyl-2-cyanosuccinate compounds, and processes for preparing 2,3-di(non-linear-alkyl)succinic acids and esters thereof by using the 2,3-di-non-linear propyl-2-cyanosuccinate compounds as intermediates are disclosed.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: March 11, 2014
    Assignees: China Petroleum & Chemical Corporation, Beijing Research Institute of Chemical Industry, China Petroleum & Chemical Corporation
    Inventors: Lunjia Xie, Yu Tian, Zaixing Feng, Siyuan Zhao, Yu Kang, Zhufang Sun