Abstract: Various embodiments relate generally to electrical and electronic hardware, computer software, wired and wireless network communications, and wearable computing and audio devices for monitoring health and wellness. More specifically, disclosed are an apparatus and a method for processing signals representing physiological characteristics sensed from tissue at or adjacent an ear of an organism. In one or more embodiments, a wearable device includes a sensor terminal and a physiological sensor coupled to the sensor terminal to sense one or more signals originating at the sensor terminal. The wearable device may also include a radio frequency (“RF”) communications interface. Also, the wearable device can include a processor configured to cause generation of data representing a physiological characteristic of the organism.

Abstract: Apparatus and methods are described, including a method for monitoring an onset of a respiratory episode in a subject. A plurality of respirations of the subject are sensed without contacting the subject, and a plurality of respiration signals corresponding to the plurality of respirations are generated. The plurality of respiration signals are combined to provide a characteristic respiration parameter of the subject. The onset of the respiratory episode is predicted from the characteristic respiration parameter. Other applications are also described.

Abstract: A method for measuring the impedance of a portion of a subject, by passing a known current provided by a current source unit between a first pair of electrodes contacting the skin surface of the subject. The measuring of a voltage with a voltage measuring instrument, between at least one second pair of electrodes contacting the skin surface of the subject when the current source unit is passing the known current through the first pair of electrodes; calculating the bio-impedance of the portion of the subject based on the known current and the calibrated voltage.

Abstract: A wearable patch and method for automatically monitoring, screening, and/or reporting events related to one or more health conditions (e.g., sleeping or breathing disorders, physical activity, arrhythmias) of a subject.

Abstract: One or more embodiments of techniques or systems for heath monitoring or monitoring one or more health parameters of a user are provided herein. Systems or components of a vehicle may monitor one or more vital or health parameters of an occupant of a vehicle, driver, passenger, etc. For example, a seat may have sensors embedded within that may measure characteristics or attributes associated with the occupant. In one example, a scale may be integrated with the seat to monitor a weight of an occupant on a day to day basis. As another example, a seatbelt or one or more portions of the seat may have heart rate monitors that check a heart rate of an occupant. Additionally, warnings or alerts may be provided when a signature is detected, such as an abnormal heart beat, etc. In this manner, health monitoring may be provided.

Abstract: A variety of methods and arrangements for sharing medical data are described. In one aspect, one or more data streams are received from one or more medical imaging/sensing or other types of devices. Frames are obtained from the streams. In some embodiments, particular frames and/or parts of frames are selectively encrypted. The frames are transmitted to a remote device, where they are rendered and/or displayed at the remote device. In various embodiments, the frames of different streams are synchronized.

Abstract: An apparatus, system, and method directed to detecting a physiological signal during discrete time separated detection windows, deriving one or more respiratory disturbance indices from the physiological signal, detecting a respiratory disturbance state in response to the one or more respiratory disturbance indices deviating from a threshold value, interpolating the one or more respiratory disturbance indices between adjacent time separated detection windows, and declaring a respiratory disturbance episode based on the detected respiratory disturbance state during the detection windows and the interpolation between detection windows.

Abstract: Mouth-breathing can be detected in early phase expiration during respiratory treatments involving a pressure support device. In accordance with some embodiments, an output signal is received from a sensor that conveys information relating to one or more parameters of the pressurized flow of breathable gas as it is delivered to an air-way of a subject. Transitions are estimated between inspiratory phases and expiratory phases of respiration by the subject based on the one or more determined parameters. A local extreme is identified in a level of a first parameter during a given expiratory phase of respiration by the subject. The level of the first parameter is analyzed as a function of time within a sampling window to determine whether the subject is breathing by mouth during the given expiratory phase. The sampling window begins at or proximate to the identified local extreme in the level of the first parameter.

Abstract: A patient monitoring system may include a microphone that generates a sound signal based on sound emanated from a patient. A patient monitoring unit may process the sound signal to identify respiration information such as respiration rate and to determine whether the patient was talking. If the patient was talking, a confidence value may be calculated, which may be used to generate a respiration information value.

Abstract: This invention is concerned with a method and apparatus for measuring and controlling the quality of physiological acoustic signals, which include tracheal breathing sounds, lung sounds, heart sounds, blood flow sounds, joint sounds, and gastrointestinal sounds. The interface between the skin and the device is carefully controlled to achieve a desirable acoustic coupling. A pneumatic feedback control system automatically adjusts of the pressure applied to the skin; another pneumatic control system adjusts the pressure inside an airtight chamber for housing the acoustic sensor. A processor assesses the signal qualities, such as amplitude and frequency spectrum, and provides feedback controls to the interface if needed. The resulting method and apparatus eliminates operator's variability and acquires physiological acoustic signals with consistent and desirable qualities for various medical diagnostic purposes.

Abstract: A system for providing an indication of cardiovascular function, includes a respiration input (1) for receiving a respiration-related signal indicative of a physical property of respiration gases administered to a patient. A hemodynamic input (2) is provided for receiving a hemodynamic-related signal indicative of a hemodynamic property. An inspiration detector (3) is provided for processing the respiration-related signal to detect times of inspiration and a measure of the size of the inspiration. A correlator (5) is provided for correlating the sizes of inspiration with the hemodynamic-related signal, to obtain the indication of cardiovascular function. The respiration-related signal is indicative of inspiration pressure, inspiration volume, or inspiration flow. The hemodynamic-related signal is indicative of blood pressure.

Abstract: An airflow signal corresponding to the breathing of the patient is obtained. A section corresponding to inspiration, having a front portion and a middle portion, is found within the airflow signal. A peak value of the front portion is found, which is compared with a value representing the airflow of the middle portion. The presence of resisted breathing is determined based on the comparison between the peak value of the front portion with a value representing the airflow of the middle portion. A baseline value of the airflow signal is found by calculating the mode of values within an airflow signal representing the pressure within a patient's naris. The section corresponding to inspiration is determined by finding peak inspiration and baseline values within a breath and searching from the peak until the baseline is reached to find the section of inspiration.

Abstract: A method for extracting the feature of an abdominal breathing is disclosed, capable of extracting the feature of an abdominal breathing, without the requirement of a standard model of an abdominal breathing and the execution of a learning process being executed prior to the method for extracting the feature of an abdominal breathing. By means of computing a plurality of intrinsic mode functions corresponding to the abdominal breathing signal received, an Euler angle function and an instantaneous frequency function of each of the plurality of intrinsic mode functions, and comparing the plurality of instantaneous frequency function with a pre-determined zero-point threshold region, the method for extracting the feature of an abdominal breathing defines one of the plurality of instantaneous frequency function as an abdominal breathing feature function, which contains the feature of the abdominal breathing. In this way, the feature of an abdominal breathing is extracted.

Abstract: The invention relates to a system for and a method of processing breathing signals. A noise reduction operation is performed on a spectral breathing signal (18) to compute an output spectral signal (38), said noise reduction operation using spectral subtraction; and a two-dimensional frequency and time filtering (32) of a gain function (30) used in the spectral subtraction of the noise reduction operation performing step is performed, for example, a two-dimensional frequency and time median filtering of the gain function. For example, said spectral breathing signal is computed based on a breathing signal.

Abstract: Provided are systems and methods for combined respiratory therapy and respiratory monitoring. A respiratory therapy and respiratory monitoring apparatus as described herein may include a spacer portion having first and second ends, wherein the first end includes a patient interface and the second end includes a respiratory therapy device. A monitoring device such as, for example, a microphone is incorporated into the spacer portion so as to record sounds from within the apparatus. The sounds may be processed and otherwise analyzed to derive one or more characteristics therefrom. These characteristics may be used to make one or more determinations relevant to the monitored and treated patient.

Abstract: This disclosure relates to methods and apparatus for detecting respiratory rate. The method for detecting respiratory rate may include: sampling respiratory waveform data in a time sequence; detecting respiratory cycles from the sampled respiratory waveform data; calculating variation degree for the sampled respiratory waveform data; calculating base length base on the variation degree; calculating smoothed length base on the base length; calculating real-time degree for each respiratory cycle base on the variation degree, sequence number of each respiratory cycle, and the smoothed length; and calculating respiratory rate base on the smoothed length and the real-time degree.

Abstract: An apparatus for determining tissue versus fluid components of an organ include a detector that generates a detector signal based on electrical signals derived from tissue and fluid. The apparatus includes a signal processor in communication with the detector which subtracts in real time a tissue component from the detector signal and produces a fluid volume signal. A method for monitoring a patient's fluid volume of a patient's organ. An apparatus for monitoring a patient's organ. A method for monitoring a patient's organ. A method to piggyback an admittance system onto a AICD/Bi-ventricular Pacemaker for a heart of a patient, in particular a weakened heart having features consistent with congestive heart failure. An apparatus for monitoring an organ, such as a heart, lungs, brain, skeletal muscle, and bladder of a patient which includes a detector which detects the admittance of the organ.

Abstract: A computer-implemented method for providing summary information for lifesaving activities is disclosed. The method involves sensing one or more activities that are repeatedly and cyclically performed on a victim by a rescuer; identifying a cyclical timing interval over which performance is to be analyzed for a integer number of cycles of the one or more activities, and gathering data from the sensing of the one or more activities during the time interval; generating, from analysis of the one or more activities, summary data that condenses data sensed for the one or more activities into a summary of the one or more activities; and providing, for display to a user, a visual summary of the performance of the one or more activities over the identified time interval.

Abstract: A plethysmograph is described that includes a test chamber having an opening; a sealing member including an annular flexible seal to receive at least a part of the head of the test animal mounted across the opening whereby the animal breathes air outside the test chamber, while the animal's body is within the test chamber; and a restraining member attachable to the sealing member, the restraining member including a clamp positionable behind the test animal's head, to prevent the animal from withdrawing its head from the restraining member. The animal is positioned in the restraining member and the sealing member is attached to the restraining member before insertion of the animal and assembly into the test chamber, avoiding previous difficulties in simultaneously placing an animal into the chamber while inserting the animal's nose into the seal. The plethysmograph also eliminates the necessity for a plunger to prevent rearward movement of the animal.

Abstract: The invention relates to estimation of a patient's propensity to suffer from symptomatic hypotension during extracorporeal blood treatment. An electromagnetic test signal, which is applied over a thoracic region of the patient via at least one transmitter electrode. A result signal produced in response to the test signal is received via at least one receiver electrode on the patient. A test parameter is derived based on the result signal. The test parameter expresses a fluid status of the thoracic region of the patient, and it is determined whether the test parameter fulfills an alarm criterion. If the test parameter fulfills an alarm criteria, an alarm signal is generated. This signal indicates that the patient is hypotension prone, and that appropriate measures should be taken.

Abstract: A device for collecting material from lung aerosols. The device functions by collecting aerosols from the lower airway separated from material in the by collecting air from the upper airway in a chamber that when full causes the remaining exhaled aerosols from the lungs to be captured by a filter. The filter collects sample of material from the separated lung aerosols.

Abstract: Disclosed is a respiratory phase determination apparatus enabling a respiratory phase determination robust to personal differences in respiration among subjects and fluctuations in respiration of subjects in person without any need for calibration.

Abstract: A method and a system for acquiring patient parameters and automatically monitoring a patient's lung injury risk include a processor and processing instructions executable by the processor to periodically and automatically determine an arterial oxygenation parameter of the patient based on first data acquired from a monitoring device coupled to the patient. The method and system determine that the mechanical ventilator is set to ventilate the patient; evaluate a lung injury risk monitoring protocol associated with the patient, the lung injury risk monitoring protocol including the arterial oxygenation parameter; and provide a lung injury risk indication when the lung injury risk monitoring protocol is satisfied.

Abstract: A device to block emesis and/or reflux includes a tube insertable into the esophagus. A valve is carried by the tube and includes a flexible sheath having an upper edge secured onto the tube and an unsecured lower circumferential edge and configured such that upon contact with emesis and/or reflux from the stomach, the flexible sheath opens in a concave configuration towards the stomach and the unsecured lower circumferential edge engages the esophageal wall and blocks emesis and/or reflux from the stomach passing into the esophagus past the valve.

Abstract: A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured to communicate with a circuit implanted in the subject within proximity to a tongue of the subject, wherein the circuit is in electrical communication with at least one electrode, receive a physiological signal from the subject via the circuit, and send a control signal to the implanted circuit in response to the physiological signal, wherein the control signal is predetermined to activate neuromuscular tissue within the tongue.

Abstract: Medication management and reporting technology, in which output from at least one sensor configured to sense physical activity in a building in which medication of a patient is located is monitored and a determination is made to capture one or more images of the medication based on the monitoring. A camera is used to capture an image of the medication and the captured image is analyzed to detect a state of the medication. Information regarding a schedule by which the medication should be taken by the patient is accessed and an expected state of the medication is determined. The detected state is compared with the expected state and a determination is made that the patient has departed from the schedule based on the comparison revealing that the detected state does not match the expected state. A message indicating the departure from the schedule is sent based on the determination.

Abstract: To assess regional oxygen uptake and/or perfusion in a patient, a volume of air inhaled by the patient is determined and, according to a method of electrical impedance tomography, a first regional lung volume is measured at a first time point of a breathold procedure. The first regional lung volume is compared to a second regional lung volume at a second time point of the breathold procedure.

Abstract: The invention is a medical monitor including an electronic circuit configured to receive a signal from the physiological sensor. A microcomputer configured to process the signal from the physiological sensor generates a value representative of the physiological parameter. The microcomputer is also configured to cause the medical monitor to display an in-service help screen on a display on the medical monitor in response to a detection of a predetermined number of out of range values of the physiological parameter. The microcomputer can also be configured to process a second signal from a second sensor representative of a second parameter and the microcomputer configured to cause the medical monitor to display an in-service help screen on a display on the medical monitor in response to a detection of a predetermined number of out of range values of the second parameter.

Abstract: A method and system for measuring respiratory rate are disclosed. In a first aspect, the method comprises measuring at least one respiration signal and filtering the respiration signal using a lowpass filter. The method includes peak-picking the respiration signal to determine the respiratory rate and determining a quality metric of the respiratory rate. In a second aspect, the system comprises a wireless sensor device coupled to a user via at least one electrode, wherein the wireless sensor device includes a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to carry out the steps of the method.

Abstract: A system and method for monitoring respiration of a user, comprising: a respiration sensing module including a sensor configured to detect a set of respiration signals of the user based upon movement resulting from the user's respiration; a supplementary sensing module comprising an accelerometer and configured to detect a set of supplemental signals from the user; an electronics subsystem comprising a power module configured to power the system and a signal processing module configured to condition the set of respiration signals and the set of supplemental signals; a housing configured to facilitate coupling of the respiration sensing module and the supplementary sensing module to the user; and a data link coupled to the electronics subsystem through the housing and configured to transmit data generated from the set of respiration signals and the set of supplemental signals, thereby facilitating monitoring of the user's respiration.

Abstract: Methods for noninvasively determining a pulmonary capillary blood flow or a cardiac output of a subject include determining data of the amount of gas exchanged between blood and gas in lungs of the subject, as well as data of an indicator of the content of the gas in blood of the subject. Such a determination may be made during two or more different states of ventilation. A geometric relationship is identified between data points, with any data points outlying the geometric relationship being disregarded. The remaining data points may be used to estimate or calculate a measure of pulmonary capillary blood flow or cardiac output. Systems that include elements that are configured to effect such methods are also disclosed.

Abstract: Disclosed herein are apparatuses and methods to monitor respiration and abnormal respiration events utilizing plethysmography. The apparatuses and methods provide an alternative to conventional respiration monitoring methods while enabling accurate yet minimally interruptive and invasive monitoring of respiration. The methods and apparatuses may be employed in the context of sleep studies to determine respiratory related sleep disorders.

Abstract: An apparatus and system are provided for monitoring an individual, a group or a community of individuals for respiratory infections. Predictive health data, such as waking peak expiratory flow rate (“WPF”) and basal metabolic temperature (“BMT”) are measured and charted to provide an indication of early stage respiratory infection. Data may be collected for target populations and reported to health agencies for use in combating the spread of infection. An apparatus is provided which can simultaneously measure WPF and BMT and other health-condition-related values and automatically transmit readings to a data collection and analysis program on a remote computer.

Abstract: This disclosure is directed to devices, systems, kits and methods for measuring peak expiratory or inspiratory flow-rate and dynamically predicting respiratory episodes. Additionally, systems for analyzing and processing the measurement in a communication networked environment are also provided. An aspect of the disclosure is directed to a respiratory device, In some configurations the respiratory device comprises a housing adaptable and configurable to communicate with an electronic device, a mouth piece having a proximal end and a distal end configurable to engage a mouth of a patient and transmit an air flow, one or more diaphragm sensors configured to detect a breath vibration from the air flow in the mouth piece, and a processor adaptable and configurable to analyze the breath vibration detected by the one or more diaphragm sensors.

Abstract: A patient monitor for displaying a physiological signal can include a visual element having a middle portion indicative of a transition in the physiological signal between physiological states. The visual element can also include first and second extremity portions, the first extremity portion extending from the middle portion in a first direction and the second extremity portion extending from the middle portion in a second direction. The visual element can also include an actionable value indicator to specify a value about the middle portion and the first and second extremity portions. The patient monitor can also include a processor configured to cause the value indicator to actuate in both the first and second directions according to changes in the physiological signal.

Abstract: This invention provides user interfaces that more intuitively display physiological data obtained from physiological monitoring of one or more subjects. Specifically, the user interfaces of this invention create and display one or more avatars having behaviors guided by physiological monitoring data. The monitoring data is preferably obtained when the subject is performing normal tasks without substantial restraint. This invention provides a range of implementations that accommodate user having varying processing and graphics capabilities, e.g., from handheld electronic devices to ordinary PC-type computers and to systems with enhanced graphics capabilities.

Abstract: A method of monitoring lung ventilation of a subject is disclosed. The method comprises recording signals from a plurality of sensing location on the chest of the subject, at least a portion of the signals being indicative of a local motion of the chest at a respective sensing location. The method further comprises operating a data processing system to analyze the signals such as to determine a status of the ventilation, thereby to monitor the lung ventilation of the subject.

Abstract: What is disclosed is a system and method for monitoring respiration of a subject or subject of interest using a thermal imaging system with single or multiple spectral bands set to a temperature range of a facial region of that person. Temperatures of extremities of the head and face are used to locate facial features in the captured thermal images, i.e., nose and mouth, which are associated with respiration. The RGB signals obtained from the camera are plotted to obtain a respiration pattern. From the respiration pattern, a rate of respiration is obtained. The system includes display and communication interfaces wherein alerts can be activated if the respiration rate falls outside a level of acceptability. The teachings hereof find their uses in an array of devices such as, for example, devices which monitor the respiration of an infant to signal the onset of a respiratory problem or failure.

Abstract: Patient mobile computing system (1) and method for predicting exacerbations in a patient illness related status, the method includes collecting patient sensor data using sensors (8), and executing a local prediction model. The local prediction model includes a Bayesian network (6) to obtain a probability of an exacerbation of a patient status. The Bayesian network (6) receives patient input data, patient sensor data, and providing probability data, and the local prediction model provides guidance data based on the probability data. The local prediction model (6) is implemented both in a portable device (1), such as a smart phone, and in a centralized patient data processing system (20).

Abstract: A system includes a sensor device having a body configured to be inserted into an airway of a patient and one or more sensors mounted in or on the body. The one or more sensors are configured to collect sensor data associated with the airway of the patient. The system also includes a signal analyzer configured to analyze the sensor data. The one or more sensors could include one or more microphones. The signal analyzer could identify volume and/or pitch characteristics of the sensor data, perform pattern recognition to identify one or more patterns using the volume and/or pitch characteristics, and use the one or more patterns to identify a type, a location, and/or a degree of airway obstruction. This could be done, for instance, to determine if the patient suffers from obstructive sleep apnea or other condition that affects his or her airway.

Abstract: The mental state of an individual is obtained to determine their well-being status. The mental state is derived from an analysis of facial information and physiological information of an individual. The well-being status of other individuals is correlated to the well-being status of the first individual. The well-being status of the individual or group of individuals is rendered for display. The well-being status of an individual is used to provide feedback and to recommend activities for the individual.

Abstract: Methods, systems, and apparatus for assessing a state of a comorbidity associated with a primary disease are provided. The methods comprise receiving at least one autonomic index, neurologic index, stress marker index, psychiatric index, endocrine index, adverse effect of therapy index, physical fitness index, or quality of life index of a patient; comparing the at least one index to at least one reference value; and assessing a state of a body system of the patient that is a site of the comorbidity, based on the comparison. A computer readable program storage device encoded with instructions that, when executed by a computer, perform the method described above is also provided. A medical device system capable of implementing the method described above is also provided.

Abstract: A method and system for sleep apnea detection are disclosed. The method comprises detecting at least one respiratory signal and utilizing a detection algorithm to automatically detect at least one sleep apnea event from the at least one respiratory signal. The system includes a sensor to determine at least one respiratory signal, a processor coupled to the sensor, and a memory device coupled to the processor, wherein the memory device includes a detection algorithm and an application that, when executed by the processor, causes the processor to utilize the detection algorithm to automatically determine at least one sleep apnea event from the at least one respiratory signal.

Abstract: A method for performing a patient oxygenation test using one or more computing devices is provided. The patient oxygenation test comprises a plurality of instructions for implementing a workflow for determining an oxygenation status for a patient. An entry or selection is received of one or more physiological parameters for the patient to be monitored during the patient oxygenation test. An entry or selection is received of one or more thresholds for at least one of the physiological parameters to be monitored during the patient oxygenation test. A determination is made as to whether any of the physiological parameters exceed limits set by the one or more thresholds. One or more actions are taken when one or more of the physiological parameters exceed the limits set by the one or more thresholds. A summary and analysis are provided of the test results.

Abstract: A method and apparatus for estimating a respiratory rate of a patient. The method comprises the steps of recording respiratory sounds of the patient, deriving a plurality of respiratory rates from the recorded sounds using a plurality of respiratory rate estimating methods and applying a heuristic to the plurality of derived respiratory rates, the heuristic selecting one of the derived respiratory rates. The selected respiratory rate is the estimated respiratory rate. The apparatus comprises at least one sensor recording respiratory sounds of the patient, a plurality of respiratory rate processors, each of the processors comprising a respiratory rate calculating method, a heuristic means for selecting one of the calculated respiratory rates and a display means for displaying the selected respiratory as the estimated respiratory rate.

Abstract: Devices systems and methods are disclosed for removing secretions from the lumen of a functional assessment catheter for the lungs. The system comprises a flushing unit configured to deliver a clearing fluid to the lumen of the pulmonary catheter to remove debris, secretions, or moisture from the lumen or sensors.

Abstract: An automated system for monitoring respiratory diseases, such as asthma, provides noninvasive, multimodal monitoring of respiratory signs and symptoms that can include wheeze and cough. Some embodiments employ a mobile device, such as a cell phone, in which raw data from a microphone and an accelerometer are processed, analyzed, and stored. Data can be collected continuously. Time domain and frequency domain analyses of signals to determine, e.g., energy, duration, and spectral content of candidate sounds can be employed to discriminate symptoms of interest from background sounds and to establish significance. Accelerometer signals are analyzed to determine activity levels. Analyses of a user's symptoms and activity level prior to, during, and after an event can provide meaningful determinations of disease severity and predict future respiratory events. The system can provide a summary of data, as well as an alarm when symptom severity reaches a threshold.

Abstract: Various embodiments may provide methods and systems capable of evaluating physiological parameter data. The methods and systems may include a receiver capable of collecting a signal representative of a physiological status of a patient, a plurality of data analysis components, wherein each of the plurality of data analysis components is capable of generating a metric based on the signal, and an arbitrator communicatively coupled to each of the plurality of data analysis components and capable of generating a single metric from the metrics generated by the plurality of data analysis components.

Abstract: A medical device system for comparing a cardiopulmonary signal to a brain signal. In one embodiment of the invention, a medical device system is provided that includes a brain monitoring element, respiratory monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a respiratory signal from the respiratory monitoring element. The processor is further configured to compare the brain signal to the respiratory signal. Methods of comparing a brain signal to a cardiopulmonary signal are also provided.

Abstract: The technology disclosed herein generally relates to a method for providing an index disorder in automated patient care. A set of device measures is stored in a database. Quantitative health care data indicators in the database are provided, where the indicators were regularly recorded by a medical device for a patient under automated patient care. Collected device measures are retrieved with a processor. An index disorder is identified through derived measure determination and statistical calculation with a processor.