Abstract: A penetrator for penetrating a stopper sealing an opening in a container. The penetrator includes a stamped piece of sheet material formed to define a shank having a length. A groove extends along the length of the shank. The shank has a pointed distal. The stamped piece of sheet material further includes a bearing plate extending from the shank at a proximal end opposite the distal end of the shank.

Abstract: A penetrator for penetrating a stopper sealing an opening in a container. The penetrator includes a stamped piece of sheet material formed to define a shank having a length. A groove extends along the length of the shank. The shank has a pointed distal. The stamped piece of sheet material further includes a bearing plate extending from the shank at a proximal end opposite the distal end of the shank.

Abstract: A process for filling and sealing a fluid-containing plastic disposable syringe that is to be sterilized, wherein the disposable syringe includes a barrel having a front end, a nozzle part having a sealing element, a plunger plug, and a plunger stop element that is placed in the area of a cylinder gripping plate, the process includes inserting and pushing the plunger plug into the front end of the barrel, using pressure and forcing a fluid medium into the barrel via the nozzle part, whereby the fluid medium pushes the plunger plug in the direction of the plunger stop element, and sealing the sealing element of the nozzle part by plastic deformation after the barrel and the nozzle part are filled.

Abstract: An apparatus for obtaining liquid samples from a fluid flow path is disclosed. The apparatus includes a housing having an access site communicating with the flow path and carrying a piercing member at a location spaced from the access site. The housing allows for translational movement of the piercing member toward the access site and into the flow path from where the sample is removed.

Abstract: A device for withdrawing a liquid from a sealed glass ampoule includes a frame holding the sealed glass ampoule in upright or slightly inclined position, such that a tip of the ampoule points upwardly. An element is provided which will press or knock against the side of the tip or neck of the ampoule in order to break the tip of the ampoule in the region of the neck. The device further includes a withdrawing element which can be introduced into the glass ampoule in an area between the bottom of the ampoule and the surface of the liquid therein, and which includes a cannula for withdrawing the liquid.

Abstract: A connecting device (1) between a first receptacle (2) and a second receptacle (4) comprising a muff joint (4a), the device comprising an apparatus (5) for perforating a stopper, including a faucet (6) and a filtering chamber (7) isolated from outside by a filter (8), two independent channels (9, 10) being provided in the perforating apparatus (5) for communicating the inside of the first receptacle (2) with the faucet (6) and the filtering chamber (7) respectively, the device further comprising an element (11) for displacing with guidance the perforating apparatus (5), an element for fastening (13) the skirt (12) on the neck (2a), a plunger (15) mounted in the internal bore (12a) on which the perforating apparatus (5) are fixed, for sliding by simple pressure, and an element (16) for definitively stopping the plunger (15).

Abstract: A plastic pre-filled syringe which includes an open ended barrel sealed at one end by a moveable stopper and sealed at the other end by a closure frangibly connected to the syringe. The syringe also includes an overcap which can be moved so to engage with the closure whereby removal of the overcap will cause the closure to be separated from the rest of the syringe and reveal the contents for injection.

Abstract: A capsule for storing a fluid, for example helium, under pressure comprises a hollow body from which extends a hollow neck. A stopper engages with the neck in a fluid tight manner. The stopper includes a main hollow portion and a stem extending outwardly from the main hollow portion. The root of the stem where it joins the main hollow portion forms a frangible section which, when broken, will allow fluid in the capsule to escape under pressure.

Abstract: An injection vessel including a glass cartridge; a rubber stopper (front stopper) and a rubber stopper (end stopper) respectively fitted to a front side and a rear side of the glass cartridge slidably in an axial direction of the glass cartridge in close contact with an inner face of the glass cartridge; a luer lock hub attached to the front end side of the glass cartridge in which a nozzle thereof is protruded outwardly; a finger grip attached to the rear end side of the glass cartridge; a plungerrod for pressing the rubber stopper (end stopper); a nozzle cap covering the nozzle; and wherein a collar consisting of a separate member is protruded equivalently or more than the nozzle or a collar portion with an elevated height attached directly to the luer lock hub is provided at a surrounding of the nozzle of the luer lock hub whereby a front end height of the collar portion is equivalent to or higher than a height of the nozzle.

Abstract: A gas delivery system includes a capsule for storing a propellant fluid, e.g. helium under pressure, e.g. between about 60 and 80 bar. The capsule is provided with a stopper having a stem formed with a frangible section. In use, mechanical means is employed to rupture the stem about the frangible section to release the fluid under high pressure.

Abstract: A radial guiding catheter comprising a first straight leg connected to a first curve. The first curve has an angle such that the first curve can be disposed just proximal to the coronary ostium. The first curve is connected to a second straight leg. The second straight leg is connected to a second curve such that the second curve can be disposed within the aortic valve. The second curve has a direction opposite the first curve. The second curve is connected to a third straight leg. The distance between the second straight leg and the third straight leg is sufficient to cause the distal end of the first straight leg to engage the left coronary artery. The third straight leg is connected to a third curve, the third curve having a direction opposite the second curve such that the third curve is disposed along the ridge of the brachial artery.

Abstract: The present invention relates to a puncture method and a puncture system. More specifically, the objective of the present invention is to carry out the aspiration of a sample from a human organ or an animal organ and the inner examination thereof, without the outward leak of the fluid and the like in the organ.The puncture method and puncture system of the present invention is in the following structure; making a parasol part arranged on a reservoir adhere through an adhesive to the site to be punctured, inserting a needle body through a sealing part of the reservoir into the site to be punctured to draw out the inner fluid, the leak of the fluid can be prevented by the reverse operation of the sealing part.

Abstract: The mechanical properties of various angioplastic surgical devices are altered in order to enhance their transportability through the vascular system by changing their operating temperature while situated within the body. Temperature increases are utilized to increase flexibility or cause devices to assume certain configurations while a temperature decrease serves to increase stiffness and rupture strength.

Abstract: A capsule for storing a propellant fluid, for example, helium under pressure comprises a hollow body which includes a frangible area. An anchor member attaches an arm to the frangible area such that when a force is applied to the arm, said force together with the helium under pressure will cause the frangible area to rupture outwardly of the hollow body thereby to release the helium.

Abstract: A catheter introducing system includes an introducer catheter comprising a flexible sheath having a hemostasis valve and an obturator having a steering mechanism operated by a proximal actuator handle. The catheter introducer system will usually be introduced with the obturator inside of the flexible sheath so that the obturator can effect steering by laterally deflecting the distal end of the combined sheath and obturator. Such catheter introducing systems are particularly useful for large diameter sheaths which are not readily introduced over guide wires. A first exemplary hemostasis valve comprises a compressed foam insert having an axial lumen therein. A second exemplary hemostasis valve comprises an elastomeric insert which receives and seals over the catheter.

Abstract: A container for delivery of flowable material has a plastic, deformable container body which can be compressed in its longitudinal direction and a neck of smaller diameter attached to one body end with formation of a projection. The delivery through the neck projection corresponds to the volume diminution obtained by the length reduction of the body, for quantitative regulation of the material delivered through the neck. A cup-shaped bushing has its floor engaged on a shoulder projection of the body. The bushing floor has a passage opening for the neck. A piston is slidable in the bushing until it contacts the bushing floor. An indicator arrangement makes a visible indication of the movement path of the piston in the bushing.

Abstract: A catheter with several independent lumens extending longitudinally through the catheter for accepting probes and for introducing fluid through the catheter and into a body cavity is disclosed. The catheter outer body has a cross-sectional maximum outer dimension. The first lumen is circular in cross-section, and has a cross-sectional dimension of approximately half the maximum outer dimension of the catheter body. The first lumen is capable of accepting various probes, as well as allowing simultaneous fluid flow through the lumen. The second lumen is crescent-shaped in cross-section and occupies at least a quarter of an arc around the cross-section of the catheter body. The large cross-section of the second lumen allows for a high fluid flow rate through the lumen. The third lumen allows for inflation of an inflation balloon (when present), and the fourth lumen allows for the passing of a portion of an instrument along the length of the lumen.

Abstract: An aspiration needle apparatus for collecting cell samples by withdrawing aspirate from tissue in a living body. An aspiration needle is provided which has a flow passage extending from its proximal extremity to its distal extremity. The proximal extremity has a hub end a cell collection chamber therein in communication with the flow passage. A vacuum container is provided which has an enclosed evacuated space evacuated to a subambient pressure to provide a predetermined volume of evacuated space devoid of a solid or a liquid and devoted solely to providing the desired vacuum. The vacuum container is sealed by a penetrable diaphragm providing access to the evacuated space. An adapter mounted on the hub and making a fluid-tight connection therewith is formed to receive the vacuum container. The adapter includes a needle having a flow passage in communication with the flow passage in the aspiration needle. A spring is carried by the adapter.

Abstract: A plastic top for adapting to a chosen syringe (14) a standard cartridge (8) of the kind having a neck (9) with a flange (10) and being closed by a rubber membrane (11) sealingly secured against the flange (10) by a metal cover (12) having its edge beaded behind the flange. This plastic top has a bore (2) for receiving the neck part (9) of the cartridge (8), which bore (2) has a diameter making it fit over the metal cover (12) and is provided with protrusions (3;9) gripping behind the edge of the metal cover (12) when the neck part (9) is inserted in the bore. The outer contour of the plastic top is adapted to the syringe type in which the cartridge is going to be used.The plastic top is provided with a thread (5;18) coaxial with the bore to receive a needle hub (13) in a way making its needle (15) penetrate the membrane (11) of the cartridge (8) when the hub (13) is mounted on the thread (5) of the plastic top.

Abstract: A cartridge-type syringe in which a cartridge, having liquid medicine or the like sealed therein, is inserted in a holder having a discharge needle at its distal end, and the cartridge is advanced to cause the discharge needle to pierce it, thereby injecting the liquid medicine or the like into an object, and when a piston rod of the cartridge is pushed to cause the discharge needle to pierce, the liquid medicine or the like will not be discharged in error in a large amount. In particular, there is provided a releaseable lock mechanism by which when a piston rod 15 is pushed, the piston rod 15 advances together with a tubular body 11 of a cartridge 10 without moving a piston 14 within the tubular body 11.

Abstract: A dispenser for dispensing a dosage or a powdery or fluid drug from a cartridge having a tubular chamber the ends of which are sealed by breakable membranes. The dispenser comprises a housing forming a cylinder which is at one end closed by an end wall through which an outlet pipe communicates with the interior of the cylinder. The other end of the cylinder is closed by a plunger which may be displaced into the cylinder. The drug cartridge is placed in a piston mounted axially displaceable in the cylinder between the end wall and the plunger, and the tubular chamber extends from one side of the piston to the other. Penetrators for breaking the membranes are provided at the inner end of the outlet pipe and the inner end of the plunger.

Abstract: An ampule filling device having an ampule for jet injection attached to a transfer apparatus having a housing, a barrier within the housing, and a push rod attached to the housing to drive the medication from a medication vial. Further, the ampule filling device is advantageously bulk sterilized during assembly, and, assembled and packaged in an aseptic manufacturing environment.

Abstract: A parenteral device having a body slidably supporting a hollow needle. The needle is slidable between a first position in which it is completely retracted within the body and a second position wherein a portion of the needle projects outside of the body. The body further houses a chamber isolated from the needle when the needle is in the first position. Movement of the needle into the second position causes an end of the needle to pierce a wall of the chamber thereby establishing communication between the chamber and needle.

Abstract: A prefilled syringe comprising a syringe body of glass; a sealing member with a through-hole extending in the axial direction of said syringe body; a tip member including a top wall, a skirt portion extending therefrom and a tubular projection passing through said top wall, said tubular projection including an outwardly extending projection and an inwardly extending projection; a covering means for closing the outwardly extending projection of said tip member; and a holding member for holding said covering member along with said tip member in place on the mouth portion of said syringe body, said tip member being liquid-tightly fixed to the mouth portion of the syringe body by said holding member.

Abstract: A blood-taking device has a comparatively flexible inner tubule and an outer tubule. There is an annular gap between both tubules. The front end of the inner tubule is provided with an end wall pressing against the annular protrusion of an end wall of the outer tubule. In order to fix the inner and outer tubules with respect to each other, the edge of the inner tubule end wall has a locking profile interlocking with a counter profile of the outer tubule. During centrifugation the inwardly directed protrusion sinks into the soft material of the end wall of the inner tubule. Thus, liquid is prevented from entering the annular gap during centrifugation.

Abstract: A prefilled syringe for one or two component medicaments is based upon the use of a vial containing a medicament or one component of a medicament, the vial having an open bottom closed by a piston. When a flexible extension of the piston is coupled with a tubular plunger, and an adaptor cap having an internal needle and an external connection for a needle is placed over a cap of the vial, the latter is converted into a prefilled syringe. The open bottom of the vial is configured so as not to interfere with handling of the vials by conventional vial sterilizing, filling and capping machinery, and may be formed so as to provide an internal shoulder which will secure a piston retention member.

Abstract: The invention relates to disposable devices for introducing substances into body cavities of a patient. The device comprises a container for holding a substance which is connected to a tube ending in an opening which is inserted into a body cavity. The opening is sealed by a frangible seal located inside the opening. An actuating rod ruptures and removes the seal upon actuation. The actuating rod is provided with supporting rods extending to the container which are connected to the container by frangible connections. The supporting rod serves as a safe-guard against accidental rupture of the seal and as a guide for a controlled movement of said the actuating rod. The supporting rod also defines and protects an area to be kept sterile. The invention also relates to a moulding apparatus and to a method for making said device.

Abstract: A cartridge-type syringe in which a cartridge, having liquid medicine or the like sealed therein, is inserted in a holder having a discharge needle at its distal end, and the cartridge is advanced to cause the discharge needle to pierce it, thereby injecting the liquid medicine or the like into an object, and when a piston rod of the cartridge is pushed to cause the discharge needle to pierce, the liquid medicine or the like will not be discharged in error in a large amount.In particular there is provided a releaseable lock mechanism by which when a piston rod 15 is pushed, the piston rod 15 advances together with a tubular body 11 of a cartridge 10 without moving a piston 14 within the tubular body 11.

Abstract: An apparatus is provided for removing a small area of epidermis from the skin to expose an intact area of dermis and subsequently deliver a liquid in contact with the exposed dermis. This method of delivery allows the rate of absorption of substances into the body to be enhanced by removal of the epidermis. A preferred embodiment removes the epidermis by forming a suction blister, the apparatus having a housing attached to the skin adhesively to define a chamber in which suction is applied. Suction is applied to the chamber without connection to an external source of suction by means of an evacuated cell separated from the chamber by a disruptable membrane. A tubular member is actuated to rupture the membrane, disrupt the blister and deliver liquid to the chamber in successive stages of operation of the apparatus.

Abstract: A syringe assembly is comprised of a plunger, a syringe barrel having a cannula collar at one end of the barrel and an interior chamber within the barrel, a hollow cannula secured within the syringe barrel collar with the cannula extending axially from the collar to its distal end, a bore extending axially through the cannula and the syringe barrel collar, a segment of the bore decreasing (e.g., tapering) in diameter as it extends in a direction from the distal end of the cannula toward the barrel interior chamber, and a sheath removably attached to the syringe barrel and covering the cannula, the sheath being affixed to a center rod extending axially from the sheath into the bore at the cannula distal end and then seating in a sealing engagement with said segment of the interior bore.

Abstract: A parenteral device having a body slidably supporting a hollow needle. The needle is slidable between a first position in which it is completely retracted within the body and a second position wherein a portion of the needle projects outside of the body. The body further houses a chamber isolated from the needle when the needle is in the first position. Movement of the needle into the second position causes an end of the needle to pierce a wall of the chamber thereby establishing communication between the chamber and needle.

Abstract: Apparatus for administering dialysis, including a separable tubing coupling (32). The tubing coupling (32) consists of a hollow cylindrical element (42, 44) insertable into the lumens of the distal and proximal regions of the fluid delivery tube (16), and has a scored circumference at which the coupling can be broken-off by application of an adequate bending force. The device allows rapid and reliable disconnecting of the patient from the dialysis apparatus, without the need for scissors or a knife to be employed.

Abstract: A positive displacement ampule for storing a fluid therein and dispensing the fluid therefrom. The ampule includes an elongate vessel for storing the fluid having a large diameter base portion at one end thereof joined to a small diameter stem portion at the other end thereof, a piston disposed in the vessel at the base end thereof for forcing the fluid from the vessel, a fracture probe for fracturing the base end of the vessel and a needle for inserting into the fractured base end of the vessel and for piercing the piston such that one end of the needle protrudes outwardly from the vessel and the other end of the needle communicates with the fluid in the vessel. In this manner, the fluid is pumped from the vessel through the needle by pushing the piston in the direction of the fluid.

Abstract: A self-sealing valve device for an angiographic catheter includes a housing having a first end adapted to form a luer lock connection with the proximal end of the angiographic catheter. A central bore extends between the first end of the housing and an opposing second end, and a deformable elastomeric slit seal is supported across the central bore to selectively seal the proximal end of the catheter. The slit seal is adapted to permit a guidewire to be passed therethrough and advanced into the catheter while sealingly engaging the walls of the guidewire to prevent blood loss through the catheter. The second end of the housing is provided with a female luer lock connection fitting for receiving the conical tip of a syringe, stopcock, or the like, and forming a pressure-tight connection therebetween.

Abstract: The monomer transfer device of this invention includes a syringe adapted to receive an ampule and adapted for connection to a vacuum source such that with the ampule open within the syringe body, the monomer is vacuumed out of the ampule and into the mixing container. Alternative embodiments accept an unbroken ampule and include an offset designed to break the ampule at its predetermined break point to permit the contents of the ampule to be vacuumed from the ampule and transferred to the mixing container. A small mesh filter or screen may be included to any of the ampule before it reaches the mixing container. Once the ampule is inserted into the syringe, an end cap is connected to close the syringe and maintain any fumes within the syringe. In the alternative embodiments, the end cap acts to force the ampule against the offset so as to cause the ampule to break.

Abstract: A syringe assembly having a syringe has an outlet opening and a tube having an inner end hermetically sealed over the outlet opening and an outer end. Thus any contents of the syringe can flow unimpeded via the outlet into the tube and vice versa. A seal hermetically closes the outer end of the tube. Such a syringe assembly is filled from a medical-liquid-holding container also having an outlet opening provided with a respective such tube whose outer end is similarly sealed. The syringe is filled by first unsealing and joining the outer ends of the tubes to each other in a sterile docking procedure, then aspirating the medicament through the unsealed and joined ends and resealing the tubes together, and finally cutting the tubes apart where they are sealed together to form two new seals on the tube outer ends.

Abstract: An improved injection port (1) for a single-use syringe is described. One embodiment of the injection port has a one-way valve system for making it more difficult to reuse the syringe (2). The one-way valve system has a flap or diaphragm valve (6) housed in a valve chamber (11) at the proximal end of port cylinder (45). When the valve (6) is seated against valve seat (51) on valve cap (5), refilling of the syringe is blocked. During injection, the valve (6) unseats and moves toward radial ribs (7), allowing flow of medicament into the proximal end of a needle (2). Another embodiment of the injection port (1) includes longitudinal grooves (8) on the interior surface of the chamber (12) at the distal end of cylinder (45). The grooves (8) vent pressure from a Luer syringe inserted in the distal end of the cylinder (45).

Abstract: A method and apparatus for administering dialysis including a breakable tubing coupling is provided wherein the tubing coupling is a hollow cylindrical element insertable into the lumens of distal and proximal sections of a fluid delivery tubing system, the breakable tubing coupling having a scored circumference on which the coupling can be broken and separated by application of a bending force. The breakable tubing coupling is suitable for medical applications including peritoneal dialysis tubing administration set utilization for administering fluid from fluid containers into a patient's peritoneal cavity through a peritoneal catheter and out of the peritoneal cavity and into a drain container wherein the tubing administration set having a tubing supply leg and a tubing drain leg requires means for separating the peritoneal catheter following dialysis at a predetermined location along the tubing path.

Abstract: A liquid container comprises a container body (2) having an opening (12) and a liquid-containing portion (2a), the container body containing liquid (W) therein; a cap (3) integrally formed with or fixedly connected to the opening after the liquid is charged in the container body, the cap having a base portion (3a) continuous to the opening, a thin-wall portion (3b) continuous to the base portion, a top portion (3c) continuous to the thin-wall portion, and at least one horn plate portion (13) continuous to the top portion, the horn portion radially outwardly extending beyond the diameter of the top portion; a cap opener (5) provided around the cap to be rotatable with respect to the cap, the cap opener having at least one craw plate (15) radially inwardly extending from inner wall of the cap opener to be in contact with the horn plate when the cap opener is rotated, an opening (5d) being made in the cap opener so as to exhaust the liquid (W) therethrough after the thin-wall portion is cut by twisting the cap o

Abstract: A positive displacement ampule for storing a fluid therein and dispensing the fluid therefrom. The ampule includes an elongate vessel for storing the fluid having a large diameter base portion at one end thereof joined to a small diameter stem portion at the other end thereof, a piston disposed in the vessel at the base end thereof for forcing the fluid from the vessel, a fracture probe for fracturing the base end of the vessel and a needle for inserting into the fractured base end of the vessel and for piercing the piston such that one end of the needle protrudes outwardly from the vessel and the other end of the needle communicates with the fluid in the vessel. In this manner, the fluid is pumped from the vessel through the needle by pushing the piston in the direction of the fluid.

Abstract: A medical syringe has a plunger bore (1 and 2) that is flexible. A hermetically-sealed glass ampule (3) containing a drug in the form of a liquid referred to generally as a sterile preparation (4) is placed in the plunger bore (1 and 2). When the plunger (1) is pulled outwardly a select distance to expose the flexible plunger bore (2), the glass ampule (3) is broken by hand-squeezing the plunger bore (2) against it. Liquid preparation (4) from the glass ampule (3) is directed through a check-valved orifice (16) at a tip of a resilient piston section (21) of the plunger (1). At the check-valved orifice (16), the preparation (4) enters into a syringe bore (6). There the preparation (4) can be injected through a conventional luer (38-40) and hypodermic needle (37) by the standard practice of depressing the plunger (1) into the syringe (7). Variations are provided for storing ampules of preparation either in or separately from the syringe. Embodiments are described for various adaptations.

Abstract: The invention relates to a flexible sealing member for an injection device, comprising a neck which encloses a channel which is open at one end and is closed at the other end by a diaphragm and has an annular flange at its closed end for a clamping connection of the sealing member in the injection device. The diaphragm is at least substantially in the shape of a spherical cap, its convex outer surface being remote from the open end of the channel in the neck. The invention further relates to an injection device comprising this sealing member.

Abstract: The invention relates to a plural-compartment dispenser for storing and mixing several components at least one of them a liquid, and in particular to a dispenser comprising a barrel, a plunger, a needle or means to connect same, finger grip or means to connect same, a stopper placed in the barrel between the needle and the plunger, said stopper having a hollow dilated central cavity open proximally and distally by apertures, said proximal aperture being releasably sealed by a bounded or fitted pressure activated blow plug.

Abstract: An injection apparatus has a jacket having a front end and a cartridge for containing a liquid having a rubber membrane closing a front end of the cartridge at the front end of the jacket. A double-ended needle is held in a needle holder such that both ends thereof are exposed and oriented, one end at the membrane for piercing the membrane to obtain the liquid from the cartridge, and the opposite end for injecting the liquid. First cooperative threads on a cap and the jacket are for screwing the cap onto the jacket and unscrewing the cap therefrom, the first cooperative threads having a first pitch and a first rotational hand.

Abstract: An ampul comprising a container having a reduced neck which supports an integral closure part that is removable by tearing away frangible portions. The neck can be sealingly applied over the seating cone of a hypodermic syringe whereby the syringe and ampul are firmly joined as one unit. The ampul is preferably produced as a single piece of a thermoplastic synthetic such as polypropylene whereby the ampul neck has sufficient elastic ductility to be elastically expanded by applying it to the seating cone of the syringe, thereby to assure a firm coherence. To permit air to enter to container when suctioning off the ampul contents, the ampul neck has on its inside an axial ventilating means.

Abstract: The invention describes an ampoule-syringe comprising a single, substantially cylindrical body, divided by a central narrow neck portion in two compartments, constituting the ampoule and the syringe respectively, the narrow neck portion forming the housing for the needle. In order to detach the syringe from the ampoule it is sufficient to break the cylindrical shell at the narrow neck portion.

Abstract: The rectal-stomal insert apparatus is used for occluding an opening in a patient's colon and preventing uncontrolled leakage during examination with a colonoscope. The apparatus includes an insertion member having an outer end, an inner end, and an exterior surface. The insertion member has an instrument channel and a separate and distinct suction channel each of which extends between the outer end and the inner end. The instrument channel is large enough to receive a colonoscope tube and is provided with a seal to seal around the colonoscope tube. An expandable occlusion member is coupled to the insertion member exterior surface. The occlusion member is made of a relatively soft material to sealingly engage and occlude the opening of the colon as the occlusion member is expanded. At the outer end of the suction channel is a longitudinal flange for receiving suction apparatus. A handle is provided at the outer end of the insertion member.

Abstract: The present invention relates to a prefilled syringe comprising a reservoir containing a single dose of medicine to be injected.The principle elements of this syringe are the reservoir (10), a blocking element (12), a capsule (13) integral with this element, a needle (14), a needle-protector (15) and a cap (16). The cap (16), in place on the reservoir, makes it possible for the operator, by pressing on this cap to make the blocking element penetrate towards the interior of the reservoir a sufficient distance to cause the precise bubble removal of the syringe. To this end, the cap is connected to the capsule (13) by a base (36) comprising a zone of reduced resistance.

Abstract: A one-piece sealed disposable enema unit with a lubricated rectal tip is disclosed. The rectal tip of the unit is sealed with a break-off tab. Attached to the tab is a sleeve which covers the exterior of the rectal tip and prevents contamination of the lubricant. Before use, the break-off tab must be twisted off and the tab with the attached sleeve removed. Therefore, the unit is tamper proof and security of the contents is insured.

Abstract: A combination mixing and discharge capsule for storing separate ingredients which are to be mixed together prior to use and including a container body for one ingredient closed at one end by a slidable piston and the opposite end being displaceably received in a cup-shaped cap which forms a second compartment with a perforated wall of the container body opposite the end containing the piston for receiving a frangible pillow containing a liquid second ingredient to be mixed with the ingredient in the body. The cap has a discharge nozzle extending axially therefrom and when the cap is displaced farther onto the body the innermost wall of the pillow is burst to cause the discharge of the liquid ingredient through the perforated wall end into the container body for mixing with the ingredient therein.