Septum Pierced By Conduit To Permit Flow Patents (Class 604/201)
  • Patent number: 10940085
    Abstract: A cartridge, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a body at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus. The body may also at least partially define first and second openings to the interior of the body, wherein the first and second openings are respectively proximate opposite first and second ends of the body. The cartridge may also include a self-sealing member at least partially closing the first opening, and a movable member at least partially closing the second opening, wherein at least a portion of the movable member is for being urged into the interior of the body for increasing pressure within the interior of the body.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: March 9, 2021
    Assignee: SORRENTO THERAPEUTICS, INC.
    Inventors: Andrew T. Baker, Elizabeth Deibler Gadsby, Russell F. Ross, Luke Hagan
  • Patent number: 10781959
    Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: September 22, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Plumptre, Christopher Nigel Langley, Richard James Vincent Avery, Joseph Butler
  • Patent number: 10661066
    Abstract: A system and method is provided for an injectable substance delivery pen comprising a microneedle hub assembly removably engaged with a pen device body which includes a cartridge, a plunger, and a drive mechanism. The hub assembly includes at least one microneedle for intradermal or shallow subcutaneous injection of the contents of the cartridge. The cartridge, plunger and drive mechanism components of the pen body are fabricated of non-compliant and non-compressible materials to allow effective communication of the cartridge contents via the microneedle patient interface.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: May 26, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Ronald J. Pettis, Frank E. Martin, Scott A. Kaestner
  • Patent number: 10653833
    Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: May 19, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, Larry B. Gray, Eric Yeaton
  • Patent number: 10625021
    Abstract: An apparatus for transdermal injection includes a collet configured to transition between first and second states. In the first state, the collet receives a cartridge with a predetermined elongate shape. In the second state, an inner surface of the collet substantially conforms to the predetermined elongate shape of the cartridge such that expansion of the cartridge, when the cartridge is pressurized, is substantially uniformly opposed.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: April 21, 2020
    Assignee: Portal Instruments, Inc.
    Inventors: Robert J. Dyer, Andrew Coats, Nikolay Lapin
  • Patent number: 10251813
    Abstract: An alignment assembly for a cartridge interface of a drug delivery device is disclosed. The assembly optionally includes a coupling for opening fluid communication between the cartridge and the delivery device. For example, the coupling optionally includes a cannula insertable through a septum of the cartridge. The assembly may include a guide for positioning the cartridge and/or an access channel thereof within a first precision of a loaded position. The assembly optionally includes a cartridge engagement fitting (for example a gripping expander sleeve collar) attached to the coupling. Optionally when the cartridge is engaged to the fitting, the coupling is retained in connection with the access channel to within a second precision. The second precision is optionally higher than the first precision. In some embodiments one or more compliant supports movably retain the fitting oriented to engage the cartridge when the access channel is in the loaded position.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: April 9, 2019
    Assignee: West Pharma. Services IL, Ltd.
    Inventors: Yossi Bar-El, Tomer Solomon, Reuven Y. Filman
  • Patent number: 10207053
    Abstract: In one aspect of the subject invention, a drug delivery device is provided which includes a reservoir for containing a medicament and has a proximal end and a distal end, the medicament including a suspension of solids in a liquid carrier. Further, the drug delivery device includes a needle in fluid communication with the reservoir and having a distal end for injection into a patient, and a proximal end in the reservoir. An accumulation surface is defined at least partially about the needle, distally of the proximal end of the needle. The accumulation surface defines a distally-extending indentation which is sized and shaped to collect, during use, solids that come out of suspension. Advantageously, with the subject invention, the accumulation surface allows for solids to accumulate at a location spaced from the proximal end of the needle, thereby minimizing the possibility of clogging the needle.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: February 19, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Roger W. Groskopf, Lionel Vedrine
  • Patent number: 10111807
    Abstract: A cartridge, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a body at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus. The body may also at least partially define first and second openings to the interior of the body, wherein the first and second openings are respectively proximate opposite first and second ends of the body. The cartridge may also include a self-sealing member at least partially closing the first opening, and a movable member at least partially closing the second opening, wherein at least a portion of the movable member is for being urged into the interior of the body for increasing pressure within the interior of the body.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: October 30, 2018
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Andrew T. Baker, Elizabeth Deibler Gadsby, Russell F. Ross, Luke Hagan
  • Patent number: 10071211
    Abstract: Devices for delivery of dry powder formulations are also provided. Devices can be single-use devices. Formulations and methods of manufacture are provided for dry powder compositions suitable for intranasal administration. Also provided are methods of use for preventing or controlling emesis and other diseases and disorders and devices, compositions, and methods for nasal delivery of therapeutic formulations.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: September 11, 2018
    Assignee: SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.
    Inventor: Tatsuo Tsutsui
  • Patent number: 10047387
    Abstract: Apparatus for automated venting and/or sampling of a specimen container having a closure sealing the interior of the specimen container from the environment is disclosed. The apparatus includes a rack holding the specimen container; a venting and/or sampling device having a needle, a chamber in fluid communication with the needle and a port in fluid communication with the chamber; a robotic transfer mechanism moveable relative to the rack; a sample removal apparatus attached to the robotic transfer mechanism having gripping features for gripping the venting device.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: August 14, 2018
    Assignee: BIOMERIEUX, INC.
    Inventors: Christopher S. Ronsick, Mark S. Wilson, Ronnie J. Robinson
  • Patent number: 9849246
    Abstract: A housing for a drug delivery device is disclosed having a first housing component adapted to receive a cartridge at least partially filled with a medicament, and a second housing component adapted to receive a drive mechanism to operably engage with the cartridge for dispensing of a dose of the medicament, wherein the first housing component comprises an insert portion to be inserted in an axial direction into a corresponding receptacle of the second housing component, and wherein the insert portion comprises at least one radially outwardly extending first interlock member to positively engage and to rotationally lock with a correspondingly shaped second interlock member of the receptacle of the second housing component.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: December 26, 2017
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Michael Jugl, Axel Teucher
  • Patent number: 9835279
    Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: December 5, 2017
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: David Plumptre, Christopher Nigel Langley, Richard James Vincent Avery, Joseph Butler
  • Patent number: 9750879
    Abstract: The bioinjection device has a housing including a pistol grip and an elongated barrel. A trigger is pivotally mounted to the housing. An inner shaft having a distal end is slidable between a first position in which the distal end of the inner shaft is disposed in the barrel and a second position in which the distal end of the inner shaft extends past an opening in the end of the barrel. A tip containing a medicament is disposed about the opening of the elongated barrel. The tip includes at least one aperture for dispensing the medicament. One can inject the medicament from the tip into a bone fracture or degenerative bone tissue during surgery by actuating the trigger of the bioinjection device. A configurable tip may be employed to control the amount and direction of dispersion of such medicament.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: September 5, 2017
    Inventors: Clifford T. Solomon, Theodore C. Solomon
  • Patent number: 9700682
    Abstract: A device for retaining and storing a liquid medium, such as medication, includes a syringe body, a retention and/or storage container, consisting essentially of a glass material, a closure element for the retention and/or storage container consisting essentially of a rubber elastic material, and at least one needle. The retention and/or storage container is a vial having a solid bottom and a pushing device is provided to move the vial in a substantially axial direction in the syringe body, the pushing device acting upon the solid bottom of the vial.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: July 11, 2017
    Assignee: Schott AG
    Inventors: Andreas Langsdorf, Inka Henze, Wolfram Beier, Axel Ohlinger
  • Patent number: 9675765
    Abstract: The syringe comprises a body containing the liquid and having fitted thereto an endpiece for fastening a needle carrier. The safety device comprises a protective sheath and a syringe support that is received inside the sheath. The sheath and the support are axially movable relative to each other between two positions, namely an uncovered position of the needle, and a retracted position of said needle. The support includes anti-rotation means for constraining it in rotation about its axis and comprising at least one pawl urged resiliently into a position in which the pawl is designed to co-operate with complementary anti-rotation means of the fastener endpiece. The sheath and the support include complementary anti-rotation means for constraining them in rotation relative to each other about their axes and activated at least when the sheath and the support are in their uncovered position of the needle.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: June 13, 2017
    Assignee: REXAM PHARMA LA VERPILLIERE
    Inventors: Julien Brand, Pascal Dugand, Sylvain Lanzi, Thierry Rimlinger
  • Patent number: 9636451
    Abstract: Fluid delivery and measurement systems and methods are disclosed.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: May 2, 2017
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
  • Patent number: 9440048
    Abstract: A catheter assembly includes a catheter having an elongate tubular body defining a lumen extending from an open proximal end to an open distal end. A cuff deployment device is concentrically supported on the elongate tubular body and is movable along a longitudinal axis of the elongate tubular body. The cuff deployment device includes a deployment mechanism having an actuated position and a non-actuated position. A cuff has a hollow cylindrical body defining an internal catheter engagement surface. The catheter assembly has a first configuration in which the deployment mechanism is in the non-actuated position and the cuff is supported by and movable with the cuff deployment device, and a second configuration in which the deployment mechanism is in the actuated position and the cuff is concentrically mounted at a fixed axial location of the elongate tubular body and is free of contact with the cuff deployment device.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 13, 2016
    Assignee: Cook Medical Technologies LLC
    Inventor: Connor Cunnane
  • Patent number: 9428327
    Abstract: A luminous syringe comprises a syringe main body with a hollow chamber formed inside. A mezzanine space is formed between an outer wall of the syringe main body and the hollow chamber, and a light emitting agent and at least one catalyst tube are received within the mezzanine space. A cap is used to close the opening formed on the mezzanine space, and a plunger is provided within the hollow chamber. When in use, a force is applied to press a locating rib on the outside wall of the syringe main body to break the catalyst tube, so that a catalyst came out from the tube is mixed up with the light emitting agent to emit fluorescent light. Then, the syringe is used to draw beverage like coke, cocktail into the hollow chamber and the plunger is pushed by hand to inject the beverage out for drinking.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: August 30, 2016
    Assignee: Guan Dai Technology Company, Ltd.
    Inventors: Ke-Chuan Liu, Jeremy Thompson, Jessica Thompson
  • Patent number: 9352138
    Abstract: An access port for introduction of a needle cannula tip into an IV tube set includes a rigid tubular housing and a resilient member disposed within an inlet of the housing. The resilient member includes a proximal face exposed to an exterior of the rigid housing and a distal face disposed within the rigid housing. An axial perforation extends through the resilient member, and is normally closed by a resilient character of the resilient member. A depression is defined in the proximal face of the resilient member, and includes sidewalls extending between the proximal face and the axial perforation to guide the needle cannula tip toward the axial perforation as a needle cannula associated with the needle cannula tip is introduced into the access port.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: May 31, 2016
    Assignee: Covidien LP
    Inventors: Eugene E Weilbacher, Gregory A Steube
  • Patent number: 9078992
    Abstract: Systems, methods, and articles for providing an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition on surface a cap element transfers antimicrobial to the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: July 14, 2015
    Assignee: Pursuit Vascular, Inc.
    Inventors: Robert J. Ziebol, Keith J. Modert
  • Patent number: 9039664
    Abstract: In a prefilled syringe including an elastic seal member to be pierced with a needle for use to eject a protein pharmaceutical preparation therefrom, the elastic seal member ensures smooth and reliable piercing thereof with the needle while reliably preventing an active substance of the protein pharmaceutical preparation from being adsorbed thereon. When a protective film (3) is laminated to a top surface of a seal body (2) of an elastic material, the protective film (3) is stretched to a greater extent by a recess (4) provided in the top surface. Further, the piercing portion to be pierced with the needle is provided in a bottom of the recess (4). Thus, the protective film (3) is formed as locally having a smaller thickness in the piercing portion.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: May 26, 2015
    Assignee: Taisei Kako Co., Ltd.
    Inventors: Yukihiro Ogawa, Yasuyuki Shiraishi, Taiji Horita, Ichiro Suzuki
  • Patent number: 8968257
    Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Uwe Dasbach, Steffen Raab, Michael Harms, Udo Stauder, Volker Korger
  • Patent number: 8900206
    Abstract: Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: December 2, 2014
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Edgardo C. Halili, Eric M. Lorenzen, Matthew William Yavorsky
  • Publication number: 20140336586
    Abstract: A drug delivery assembly comprises a housing (110), a piston (120) axially displaceable in the housing, and a variable volume reservoir (105) formed by the housing and the piston and containing a fluid first drug. The assembly further comprises an exterior fluid inlet (150) arranged in or configured to be arranged in fluid communication with the reservoir, a fluid outlet (145) arranged in or configured to be arranged in fluid communication with the reservoir, biasing means (130) configured for moving the piston forwards, and releasable retaining means (113) configured for retaining the piston in an initial position, whereby the biasing means is allowed to move the piston forwards to expel fluid drug from the reservoir when the retaining means is released.
    Type: Application
    Filed: November 30, 2012
    Publication date: November 13, 2014
    Applicant: NOVO NORDISK A/S
    Inventors: Henrik Bengtsson, Jonas K. Pedersen, Rikke B. Andersen, Jeppe Sturis, Kezia A. Juul, Lars Eilertsen, Ulla Ribel-Madsen
  • Patent number: 8870829
    Abstract: Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: October 28, 2014
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Edgardo C. Halili, Eric M. Lorenzen, Matthew William Yavorsky
  • Patent number: 8864719
    Abstract: A needle and receiver assembly for use with a syringe cartridge filled with medicine includes a cartridge receiver having a hollow interior, an open end sized for receiving at least part of the syringe cartridge, and a closed end opposite the open end. The assembly includes a needle mounted on the receiver having a fluid passage extending between a sharp delivery tip at a distal end of the needle and a sharp access tip at a proximal end of the needle opposite the delivery tip positioned inside the hollow interior of the receiver. The assembly includes a cutter movably mounted in the hollow interior of the receiver for movement relative to the receiver and the needle to cut the diaphragm of the cartridge when received in the hollow interior of the receiver.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: October 21, 2014
    Assignee: Covidien LP
    Inventors: David M. Selvitelli, Melvin A. Finke, Kathleen Tremblay
  • Patent number: 8864740
    Abstract: A needle assembly comprises a body configured for attachment to a drug delivery device. The body defines a cavity. A septum is positioned within the cavity and a stopper positioned within the cavity such that the cavity, septum, and stopper define a reservoir. A double ended needle is positioned in the stopper and septum, the needle comprising a proximal end and a distal end. A release mechanism is positioned near a distal end of the body. A biasing element is positioned to drive the stopper. During a dose dispensing step, the release mechanism drives the proximal end of the needle out of the septum so that the proximal end resides in said reservoir. The biasing element may also drive the stopper proximally.
    Type: Grant
    Filed: September 28, 2011
    Date of Patent: October 21, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Schabbach, Daniel Wagner, Houda Mihad
  • Patent number: 8858511
    Abstract: Fluid delivery and measurement systems and methods are disclosed.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: October 14, 2014
    Assignee: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
  • Patent number: 8801673
    Abstract: A safety pen needle assembly is provided herein which includes a hub; a needle fixed to the hub having a distal end, formed for insertion into a patient, and a proximal end; a shield; a biasing means disposed to urge the shield from a first position to a second position; and, at least one adjustable tab or locking finger on the hub, the tab or finger being adjustable from a first state to a second state. With the tab or finger being in a first state, the tab or finger interferingly engages the shield so as to restrict movement thereof. The tab or finger in the first state retains the shield in its first position with the proximal end of the needle being exposed. With the tab or finger being in the second state, the tab or finger does not interferingly engage with the shield. As such, the shield is permitted to be urged proximally to the second position by the biasing means. In the second position, the shield covers the proximal end of the needle.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: August 12, 2014
    Assignee: Becton Dickinson & Company
    Inventors: Eliot Zaiken, Stephen Richards, Joseph Alu, Michael Vincent Quinn
  • Publication number: 20140221916
    Abstract: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: ANTARES PHARMA, INC.
    Inventors: Thomas E. KRAMER, Peter L. SADOWSKI
  • Publication number: 20140207104
    Abstract: A fluid dispensing device is provided for dispensing a measured amount of fluid into a living organism. The device has a needle having a first end and a second end. The needle is adapted for interfacing, on the first end, with a septum of a flexible hollow membrane, and at a second end thereof, for subcutaneously inserting into a living organism. The needle is guided by a guide to permit an injection into the living organism at a substantially non-orthogonal angle with respect to a surface of the living organism. The first and second ends of the needle pierce their respective piercing surface while translating together in a common direction. In other embodiments, the dispensing device includes a main housing, a flexible fluid reservoir, an injection assembly and a trigger mechanism. The main housing houses the operative components of the device.
    Type: Application
    Filed: July 25, 2012
    Publication date: July 24, 2014
    Inventors: Lucien Vouillamoz, Melissa Rosen, Judy L. Walish, Daniel Yasevac, Michel Bruehwiler
  • Patent number: 8764723
    Abstract: Various embodiments of the present invention are directed to equalizing pressure in a reservoir containing fluidic media, possibly due to imperfect installation of the reservoir or an external influence such as an altitude or a temperature change. In various embodiments, fluidic media may be expelled from the reservoir through a needle and contained in an interior volume of a pierceable member before the needle pierces the pierceable member to establish a flow path to a user. In other embodiments, fluidic media may be expelled through a port of the reservoir into a chamber. In further embodiments, fluidic media may be expelled through a channel in a plunger head and out a passage in the reservoir when the channel and passage are aligned. In other embodiments, fluidic media may be expelled through a valve, and the valve may be pierceable by a needle to establish a flow path to the user.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: July 1, 2014
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Colin A. Chong, Julian D. Kavazov, Eric M. Lorenzen
  • Publication number: 20140180244
    Abstract: A locking assembly for a medication dispensing device including a housing, a drive member, a medication cartridge having a barrel holding medication between a movable plunger and a septum, and a dose delivery mechanism for controlling the advancement of the drive member. The locking assembly, in one form, includes a lock member, biased to move from a first position to a second position, with a first actuating element. The locking assembly also includes a second actuating element disposed on the drive member and cooperatively configured with the first actuating element. If the drive member of the device moves rearward from the shipped position due to a freezing of the medication, the second actuating element engages the first actuating element such that the lock member moves from the first position to the second position to lock the medication dispensing device from further dose dispensing.
    Type: Application
    Filed: December 17, 2013
    Publication date: June 26, 2014
    Applicant: Eli Lilly and Company
    Inventor: Jaime Ray Arnett
  • Patent number: 8753326
    Abstract: Various embodiments of the present invention are directed to equalizing pressure in a reservoir containing fluidic media, possibly due to imperfect installation of the reservoir or an external influence such as an altitude or a temperature change. In various embodiments, fluidic media may be expelled from the reservoir through a needle and contained in an interior volume of a pierceable member before the needle pierces the pierceable member to establish a flow path to a user. In other embodiments, fluidic media may be expelled through a port of the reservoir into a chamber. In further embodiments, fluidic media may be expelled through a channel in a plunger head and out a passage in the reservoir when the channel and passage are aligned. In other embodiments, fluidic media may be expelled through a valve, and the valve may be pierceable by a needle to establish a flow path to the user.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: June 17, 2014
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Colin A. Chong, Julian D. Kavazov, Eric M. Lorenzen
  • Patent number: 8728042
    Abstract: An injection syringe, having a syringe cylinder, a plunger rod inserted therein and connected to a stopper by way of a coupling part, and a module that is provided in the proximal end of the syringe cylinder and having a cannula, mounted in a cannula holder received in a guided sleeve, and a sealing insert for the fluid-tight closure of the proximal end of the syringe cylinder and a protection cap for protecting the cannula, wherein the protective cap on the inner circumference has ribs extending in an axial direction, which engage in corresponding grooves of the driving part for a rotary drive thereof, and wherein in the sealing insert a hollow space is formed, which is closed on the proximal side and on the distal side transitions into an opening, by way of which a tip of the coupling part can be coupled to the hollow space.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: May 20, 2014
    Assignee: Pharma Consult GES.m.b.H.
    Inventor: Brigitte Pickhard
  • Patent number: 8715248
    Abstract: A vascular access device for communicating with the vascular system of a patient may include a status indicator. The status indicator may detect and signal that a period of time has elapsed in relation to the use of the vascular access device.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: May 6, 2014
    Assignee: Becton, Dickinson and Company
    Inventor: Austin Jason McKinnon
  • Publication number: 20140088514
    Abstract: The present invention inter-alia relates to an apparatus comprising a needle guide configured to at last partially receive a needle of a needle assembly in a longitudinal opening and to center the needle of the needle assembly in the longitudinal opening, wherein the needle guide is longitudinally compressible.
    Type: Application
    Filed: May 4, 2012
    Publication date: March 27, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: Philippe Nzike
  • Publication number: 20140081239
    Abstract: An injection device (100), including a base (104), a sliding body (116) slidably connected to the base (104), a double-ended needle (120) fixed to the sliding body (116), a biasing member (124) for proximally biasing the sliding body (116) with respect to the base (104), and for retracting the needle (120) into the device (100) subsequent to activation of the device (100), a medicament cartridge (128) for holding a medicament, slidably connected to the sliding body (116), and a stopper (132) slidably disposed within the medicament cartridge (128). The base (104) has a proximal end (108) and a surface (164) disposed at a distal end (112) thereof for contacting a patient's skin. The base (104) also has a first locking mechanism. The sliding body (116) has a locking feature and a second locking mechanism. The second locking mechanism locks the medicament cartridge (128) relative to the sliding body (116) upon completion of displacement of the medicament cartridge (128) relative to the sliding body,(116).
    Type: Application
    Filed: May 18, 2011
    Publication date: March 20, 2014
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventor: Richard Cronenberg
  • Patent number: 8672894
    Abstract: The invention relates to a protection device (10) for a needle of an assembly or of an injection device having a hub portion provided with a needle, the said protection device (10) comprising: an outer casing (20) formed of a first material; and an inner casing (30) formed of a second material different from the said first material and defining a cavity (32) for receiving in a sealing way at least the hub portion, said cavity (32) having an inner wall (34); attachment means (40) defined in the said cavity (32) to removably engage and secure said protection device (10) at least along a sealing line to the injection device; the protection device being characterized in that it further comprises aspiration limiting means (40, 50) for limiting the deformation of said cavity (32) when said protection device (10) is separated from the assembly or the injection device.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: March 18, 2014
    Assignee: Becton Dickinson France S.A.S.
    Inventor: St├ęphane Bonnet
  • Publication number: 20140066859
    Abstract: In a prefilled syringe including an elastic seal member to be pierced with a needle for use to eject a protein pharmaceutical preparation therefrom, the elastic seal member ensures smooth and reliable piercing thereof with the needle while reliably preventing an active substance of the protein pharmaceutical preparation from being adsorbed thereon. When a protective film (3) is laminated to a top surface of a seal body (2) of an elastic material, the protective film (3) is stretched to a greater extent by a recess (4) provided in the top surface. Further, the piercing portion to be pierced with the needle is provided in a bottom of the recess (4). Thus, the protective film (3) is formed as locally having a smaller thickness in the piercing portion.
    Type: Application
    Filed: April 16, 2012
    Publication date: March 6, 2014
    Inventors: Yukihiro Ogawa, Yasuyuki Shiraishi, Taiji Horita, Ichiro Suzuki
  • Patent number: 8632504
    Abstract: A device for storing and administering drug includes a housing, a sealing element (3) and a separate low friction plunger (4) which is substantially-permeable to gas over time. The sealing element (3) is typically broken to allow delivery of the drug. The housing (2) may be filled with the drug through an opening other than the opening through which the pusher (13) enters the housing to move the plunger so as to expel the drug during administration to a patient.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: January 21, 2014
    Assignee: Oval Medical Technologies Limited
    Inventor: Matthew Young
  • Publication number: 20140012207
    Abstract: An auto-injector confines all functional components inside an enclosed housing, to keep its needle out-of-sight, at all times. Within the housing, a needle holder positions a needle at a location. A drive mechanism then simultaneously engages the needle with a fluid source and accelerates it with a predetermined momentum for insertion into a patient. After fluid delivery, the withdrawn needle is moved to storage within the housing for subsequent disposal.
    Type: Application
    Filed: September 9, 2013
    Publication date: January 9, 2014
    Applicant: Avant Medical Corp.
    Inventors: John B. Slate, Andrew C. Barnes, Corey M. Magers
  • Patent number: 8617108
    Abstract: A lifter assembly for actuating a needle of an automatic medication delivery device, includes a motor, a speed reduction device driven by the motor, an output shaft driven by the speed reduction device via a rigid transmission device, a driving lever configured to move the needle, the driving lever being connected to and driven by the output shaft, and a sensing device configured to sense the rotation position of the output shaft. The speed reduction device comprises a worm in mesh with a worm gear. The output shaft, the worm gear and the rigid transmission device cooperatively constitute a four-bar linkage mechanism.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: December 31, 2013
    Assignee: Johnson Electric S.A.
    Inventors: Mohanlal Ramadoss, Wai To Li, Yue Fu Zhu, Xiang Dong Jiang
  • Publication number: 20130274679
    Abstract: The present invention relates A needle assembly for a drug delivery device comprising: a cup-shaped receptacle of non-circular cross section having a bottom section supporting a needle element being adapted to penetrate a pierceable seal of a cartridge to be disposed in a cartridge holder of the drug delivery device, wherein the receptacle comprises fastening means adapted to engage with fastening means of a support section of the cartridge holder for releasably fastening the needle assembly, wherein the fastening means are convertible into a release configuration by changing the radial distance of mutually corresponding fastening means through twisting the receptacle with respect to the support section.
    Type: Application
    Filed: December 8, 2011
    Publication date: October 17, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Michael Jugl, Axel Teucher
  • Publication number: 20130261560
    Abstract: The present invention relates to a cartridge holder assembly for a drug delivery device comprising of a cartridge holder adapted to receive a cartridge filled with a medicament to be dispensed by the drug delivery device, wherein the cartridge holder comprises a first through opening at a distal end section to receive a piercing element adapted to penetrate a sealing member of the cartridge, a support structure adjacently arranged to the first through opening; and a constriction member arranged between the support structure and a distal end face of the cartridge and having a second through opening smaller than the first through opening.
    Type: Application
    Filed: December 20, 2011
    Publication date: October 3, 2013
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Jugl, Torsten Kraft
  • Publication number: 20130226096
    Abstract: The present invention relates to a cartridge for a drug delivery device comprising of a container at least partially filled with an injectable medicament, at least one sealing member disposed at a distal end of the container, the sealing member being pierceable by a piercing element for expelling a dose of the medicament, and at least one fixing cap of circular or cylindrical geometry comprising a centric through opening at a distal end face giving access to the sealing member disposed underneath, and comprising at least in sections a structurally strengthened surface structure to keep the sealing member in position and/or to counteract a pressure-induced mechanical deformation of the sealing member, and wherein the distal end face of the fixing cap comprises at least one radially extending corrugation or bead.
    Type: Application
    Filed: November 14, 2011
    Publication date: August 29, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: MIchael Jugl, Turhan Ergel
  • Publication number: 20130184541
    Abstract: An infusion set component of a fluid infusion device and/or a fluid infusion port component for delivery of fluid to a patient is compatible with a cooperating fluid channel module. The fluid channel module includes a body section having coupling features to mate with a base of the component. The fluid channel module also includes an interior fluid flow channel formed within the body section to receive fluid from the fluid infusion device and/or from a syringe or pen delivery device. The fluid channel module also includes a conduit having a first end in fluid communication with the interior fluid flow channel, and having a second end to deliver the fluid to the patient.
    Type: Application
    Filed: May 3, 2012
    Publication date: July 18, 2013
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: David Christopher Antonio, Sumona Nag Adhya, Jose J. Ruelas, Eric Allan Larson
  • Patent number: 8480651
    Abstract: The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: July 9, 2013
    Assignee: Covidien LP
    Inventors: Ferass Abuzaina, Ahmad Robert Hadba
  • Publication number: 20130110053
    Abstract: A drug injection apparatus includes a drug container, a needle tube having a first needle tip and a second needle tip, a needle-holding portion which holds the central portion of the needle tube, and a drug container mount from which the second needle tip projects. The drug container has a container body, having a contact portion to be penetrated by the second needle tip and a pressing portion that faces the contact portion, wherein the pressing portion is to be pressed toward the contact portion side so as to deform; a seal member attached to a portion of the contact portion to be penetrated by the second needle tip, and adapted to be brought into close contact with the circumferential surface of the needle tube in liquid-tight manner; and a protective plate adapted to avoid the pressing portion from being penetrated by second needle tip inserted into the container body.
    Type: Application
    Filed: June 20, 2011
    Publication date: May 2, 2013
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Keisuke Yoshino, Miyuki Koyama
  • Patent number: RE47614
    Abstract: The present invention relates to drug delivery device and a and method of manufacturing a drug delivery device with a housing having a proximal end and a distal end, a cartridge adapted to accommodate a drug, a cartridge retaining member adapted to retain the cartridge, the cartridge retaining member being secured to the housing, and a spring washer being arranged within the housing so as to exerting a force on the cartridge and securing the cartridge against movement with respect to the cartridge retaining member and against movement with respect to the housing.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: September 24, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Harms, Steffen Raab